Abreva Topical: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Uses

Docosanol is used to treat “cold sores/fever blisters” (herpes labialis). It can speed up healing of the sores and decrease symptoms (such as tingling, pain, burning, itching). It works by blocking the virus that causes the cold sores (herpes simplex) from entering the healthy skin cells and growing in number. This medication does not cure herpes and does not prevent passing the infection to someone else. It does not prevent a future occurrence.Do not use this medication to treat canker sores (sores found commonly in the mouth), shingles, or genital herpes.

How to use Abreva Cream

Follow all directions on the product package, or use as directed by your doctor. Use this medication at the first signs of a cold sore (such as tingling, burning, redness, or a bump). Wash and dry your hands before applying the medication. Clean and dry the affected areas. Apply a thin layer of medication to completely cover the area of the cold sore or the area of tingling/itching/redness/swelling and rub in gently, usually 5 times a day every 3-4 hours, or as directed by your doctor. Wash your hands with soap and water after applying. If you have any questions, ask your doctor or pharmacist.

Apply to skin only. Do not apply this medication in or near the eyes since this medication can irritate the eyes. If you do get medication in your eyes, flush with plenty of water. Do not apply inside the mouth or nose.

Remove any cosmetics from the affected area before applying. You may apply cosmetics after applying but use a separate applicator (such as a disposable cotton swab) on infected areas to prevent spreading the infection. If you accidentally wipe off the medication, reapply as soon as possible.

Dosage is based on your medical condition, type of infection, and response to treatment. Do not use this drug more often or for longer than directed.

Use this medication regularly to get the most benefit from it. This medication works best when the amount of drug absorbed by the skin stays at a constant level. Use this drug at evenly spaced intervals. To help you remember, use it at the same times each day.

Cold sores (herpes) can spread easily. Docosanol does not prevent the spread of herpes. Avoid close physical contact with others (such as kissing) during an outbreak until the cold sores have completely healed. Also, try not to touch the cold sore, and wash your hands if you do touch the cold sore.

Stop using this medication and tell your doctor if your cold sores get worse or last for more than 10 days.

Side Effects

Redness or swelling may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US –

In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before using docosanol, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

Does Abreva Cream interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose

This medicine may be harmful if swallowed. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Do not share this medication with others. Doing so may spread the infection.

Cold sore outbreaks can be caused by many factors such as stress, hormonal changes (such as pregnancy, menstrual period), injury/surgery on the mouth (such as dental work), tiredness, sunlight, cold weather, or fever/cold/flu.

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.

Store at room temperature. Protect from freezing. If you have any questions about storage, ask your pharmacist. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Images

Abreva 10 % topical cream

Color: whiteShape: Imprint:

This medicine is a white, cream

Abreva 10 % topical cream

Color: whiteShape: Imprint:

This medicine is a white, cream

Abreva 10 % topical cream

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This medicine is a white, cream

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

6 of the best cold sore creams

We include products we think are useful for our readers. If you buy through links on this page, we may earn a small commission Here’s our process.

Medical News Today only shows you brands and products that we stand behind.

Our team thoroughly researches and evaluates the recommendations we make on our site. To establish that the product manufacturers addressed safety and efficacy standards, we:

• Evaluate ingredients and composition: Do they have the potential to cause harm?
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Cold sores are blisters that usually appear on the lips or around the mouth. The herpes simplex virus causes cold sores, and while there is no cure, cold sore creams can ease symptoms and slightly speed up healing.

Quick links

• Best cold sore patch: Compeed Cold Sore Patches
• Best cold sore cream: Abreva Cold Sore Cream
• Best for early relief: Zilactin Cold Sore Gel
• Best for kids: Cold Sores BeGone Stick
• Best menthol treatment: Quantum Health Lip Clear Lysine+ Ointment
• Best for reducing redness and scabs: Orajel Moisturelock Cold Sore Symptom Treatment

This article looks at how to identify a cold sore, some of the best cold sore creams, and other remedies that can reduce the symptoms. It also explores ways to prevent cold sores.

Cold sores are a symptom of herpes, a viral infection.

The herpes virus can lie dormant for long periods. When it is active, it can cause cold sores in response to certain triggers, such as stress or exposure to sunlight.

People may confuse cold sores with other lesions, such as canker sores. Canker sores are ulcers that form inside the mouth and may look like white circles with reddish halos.

Cold sores are fluid-filled blisters that usually appear on the lips or around the mouth. They go through the following stages:

1. The affected area tingles, itches, or burns.
2. A hard spot appears.
3. The spot develops fluid-filled blisters.
4. The blisters may leak or ooze liquid.
5. They burst and crust over.

Cold sores can resemble other skin lesions, so it is a good idea for people to get a diagnosis from a doctor, nurse, or pharmacist before considering a treatment.

Learn more about the differences between canker sores and cold sores.

Medical News Today chooses cold sore creams according to the following criteria where possible:

• Active ingredients: MNT selects products with active ingredients that can help soothe cold sore symptoms.
• Age suitability: MNT chooses products that are also suitable for children.
• Cost: MNT selects products that fit a range of budgets.

Below are some of the best cold sore creams available to purchase online.

Please note that the writer of this article has not tried these products. All information presented is purely research-based and correct at the time of publication.

Medical News Today follows a strict product selection and vetting process. Learn more here.

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Best cold sore patch: Compeed Cold Sore Patches

• List price: around $23 for 15 patches
• Active ingredients: salicylic acid and hydrocolloid-075 gel
• Dose: wear for 24 hours a day until the cold sore disappears
• Pro: patches are invisible and discreet
• Con: some reviewers state the new design of this product is not as efficient as the old design

Each small patch covers a cold sore and contains hydrocolloid-075 gel. According to research from 2014, hydrocolloids can absorb excess liquid from the skin.

The manufacturers of these patches recommend applying a patch at the first symptom of a cold sore.

The patches are invisible, and reviewers report that they can reduce the appearance of cold sores. In addition, each patch acts like a shield to help prevent the virus from spreading.

A 2008 study comparing antiviral creams with a Compeed product concluded that the latter immediately provided wound protection and was a safe alternative for people who cannot use antiviral creams.

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Best cold sore cream:

Abreva Cold Sore Cream

• List price: around $26
• Active ingredients: docosanol 10% and benzyl alcohol
• Dose: apply 5 times per day until the cold sore disappears
• Pro: docosanol has Food and Drug Administration (FDA) approval for the treatment of cold sores
• Con: people must apply this product 5 times per day for best results

This antiviral cream has FDA approval and contains 10% docosanol. This helps treat recurrent cold sores by stopping the herpes virus from entering surrounding cells. This helps protect the healthy area around the cold sore.

The manufacturer claims that if a person uses the cream at the first sign of a cold sore, the cream can heal the sore in as few as 2.5 days. However, the company acknowledges that the average healing time for someone using their product is 4.1 days.

The company says this white cream penetrates deep into the skin, is tasteless, and has no smell.

A person should not use the product if they are pregnant or nursing unless their doctor says it is safe.

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Best for early relief: Zilactin Cold Sore Gel

• List price: around $11
• Active ingredients: benzyl alcohol
• Dose: apply no more than 3–4 times per day
• Pro: this product has a more affordable price than some options
• Con: some reviewers mention difficulty removing the protective layer

This gel dries, forming an invisible protective layer over a cold sore. According to the manufacturers, the patented bioadhesive formula promotes healing.

People should not remove the film layer before they apply more product, as doing so may cause skin irritation.

The gel contains 10% benzyl alcohol, which may help relieve the pain of a cold sore for 6 hours.

As with the other products, a person should use this when they first notice symptoms of a cold sore.

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Best for kids: Cold Sores BeGone Stick

• List price: $12.99
• Active ingredients: lemon balm, grapefruit seed extract, and L-lysine
• Dose: apply as needed
• Pro: the company claims it is safe for both children and adults
• Con: does not contain any medicated ingredients

The company states that while it has designed this product for children, it is also suitable for adults. It is in chapstick form, so a person can easily carry it around and apply it as necessary.

The product does not contain medicated ingredients making it suitable for children. Most of the ingredients are certified organic. However, it contains beeswax, so it is not suitable for vegans.

The company recommends applying the product during early symptoms. The formula may tingle after application.

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Best menthol treatment: Quantum Health Lip Clear Lysine+ Ointment

• List price: $9.99
• Active ingredients: menthol 0.1% and L-lysine
• Dose: apply every 2 hours
• Pro: can moisturize lips as well as relieve pain from cold sores
• Con: contains beeswax, so not suitable for vegans

This ointment helps moisturize the lips as well as provide relief from cold sore symptoms.

It contains menthol to help soothe pain as well as L-lysine, calendula, olive oil, and propolis. These ingredients may help reduce dry skin.

The company recommends a person applies every 2 hours for best results.

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Best for reducing redness and scabs: Orajel Moisturelock Cold Sore Symptom Treatment

• List price: $12
• Active ingredients: menthol, allantoin, benzocaine, and white petrolatum
• Dose: apply no more than 3–4 times per day
• Pro: can mask redness and soften scabs from cold sores
• Con: the manufacturers display a warning about the formula potentially causing methemoglobinemia

This treatment can help reduce the redness, scabs, itching, and dryness due to cold sores. In addition, it can help to heal chapped lips.

The company recommends blending the product into the lips until the green tint disappears. A person should not apply this cream more than 3–4 times per day.

The label warns that using this product risks a person developing methemoglobinemia, a condition where too little oxygen is in the body’s cells. The company states people should seek immediate medical attention if they experience skin discoloration, headaches, increased heart rate, shortness of breath, dizziness, and fatigue.

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The following table compares the cold sore treatments in this article.

There is no cure for herpes and, therefore, no cure for cold sores. However, common cold sore treatments can reduce the symptoms and slightly speed up healing.

Effective cold sore creams may include:

• Antiviral ingredients: Some examples are acyclovir, penciclovir, and docosanol, but these medications may only work marginally better than a placebo at reducing the pain of a cold sore within 24 hours.
• Zinc oxide: Participants in an older study applied a zinc oxide cream or a placebo to their cold sores every 2 hours. Those who used the cream within 24 hours of the cold sore developing had faster healing times and less severe symptoms than those who used the placebo.
• Anesthetic: A cream containing an anesthetic can numb a cold sore, reducing pain, itching, and burning. This does not speed up the healing time.

A cold sore cream works best if a person applies it as soon as they notice any symptoms.

Beyond patches, creams, and gels, other over-the-counter (OTC) medications and home remedies may help reduce cold sore symptoms. These include:

• OTC pain medications: Drugs such as acetaminophen (Tylenol) or ibuprofen (Advil, Motrin) may help reduce the pain and swelling of a cold sore.
• Cold compresses: These may also help with pain or discoloration. A person can make a compress by covering an ice pack in a cloth and holding it against the affected area.
• Kanuka honey: A 2019 study suggests that Kanuka honey may be as effective as antiviral medication for treating cold sores.

Cold sores can have many different triggers, including stress and long periods of sun exposure. Noticing and managing these triggers, when possible, may help reduce the frequency of cold sores.

If sun exposure is a trigger, using a lip balm that contains SPF and sunscreen on the face may help.

Learn more about sunscreens here.

Cold sores are highly contagious. To prevent the spread, a person should refrain from:

• sharing personal items, such as face and body towels, toothbrushes, and lipsticks or lip balms
• touching the cold sore, unless they are applying medication or a remedy
• kissing or having oral sex, as the virus can spread during these activities

After touching a cold sore, wash the hands thoroughly with soap and water.

A person can typically treat their cold sore at home with OTC medication or home remedies. However, people should consider consulting a doctor if a cold sore:

• is large or very painful
• is not healing on its own
• keeps coming back

People with weakened immune systems should also speak with a doctor about the need for prescription antiviral medications.

Here, we look at some common questions about cold sore creams.

Do cold sore creams work for canker sores?

Most cold sore creams are for external use only. Canker sores form inside the mouth, so people should not use cold sore creams as treatment. Always follow the manufacturer’s instructions and the advice of a pharmacist, nurse, or doctor.

Can you use cold sore cream while pregnant?

Most cold sore creams are safe to use during pregnancy, but a person should discuss this first with a doctor or healthcare professional.

How long does it take for cold sore cream to work?

A person may start to notice improvements within 2 days of using medication, but a cold sore can still take up to 2 weeks to fully heal.

Does hemorrhoid cream work on cold sores?

Hemorrhoid cream may help reduce itchiness and redness, but healthcare professionals typically do not recommend applying this cream to the mouth or lips. Always follow the manufacturer’s instructions for use.

Can I use cold sore cream on genital herpes?

People should not use cold sore creams to treat genital herpes.

Does cold sore cream work?

Cold sore cream does not cure herpes or clear the virus from the body. It may help reduce symptoms of a cold sore and slightly speed up healing.

Cold sores are a symptom of herpes. They are fluid-filled blisters that can develop in response to certain triggers, such as sunlight exposure or stress.

Cold sore creams can help relieve symptoms and may speed up healing slightly. Anyone with severe or persistent cold sores should receive medical advice.

drug treatment, causes, development of the virus

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Contents

• What causes herpes in the mouth
• What can cause disease
• How a virus develops in a patient’s body
• What medicines can be used to treat herpes
• Conclusion

Some viral diseases are not dangerous, but can negatively affect the appearance of the person who has become a victim. One of these disease-causing processes is herpes, known to the general public as a cold on the lips. It manifests itself in the form of ulcers that provoke painful sensations of the patient on the lips and skin of nearby areas. However, there are times when a person develops herpes on the gums.

This virus is harmless to those in relatively good health. The risk group consists of those people who have a weakened immune system, patients with diseases such as AIDS, HIV, leukemia. Doctors also include people who have recently undergone transplantation, the elderly, and infants in this group.

Herpes on gums

What causes herpes to appear in the oral cavity

Dentists and other specialists refer to the virus that causes herpes as herpes simplex type 1. It is worth noting that this is one of the 80 species of this virus identified to date. The virus, which causes painful and ugly ulcers on the lips, gums or palate, has a minimal degree of danger to humans. However, it has a common feature along with the rest of the representatives of this class of viruses: when it enters the patient’s body, the infection begins to fight for the opportunity to progress. Often this struggle occurs in a latent, that is, hidden form.

The main type of person-to-person transmission of the virus is oral contact.

If a patient with herpes has active ulcers, there is a chance that the infection will enter the patient’s saliva. In order to prevent the spread of viral cells, it is worth taking the following measures:

• avoid kissing and any tactile contact with healthy people;
• do not allow the sharing of drinks, food and kitchen utensils;
• prevent the use of the patient’s toothbrush and dental floss;
• do not share a towel with healthy people;
• with active ulcers, the patient should not be allowed to come into contact with infants and people who have a weakened immune system.

Following these simple guidelines will help prevent further spread of the infection between people and make it easier to treat the disease, making it faster and more effective.

Herpes lesions on lips, gums, palate and tongue

Before treating herpes that has affected the lips, palate or gums, it is worth consulting with a specialist in order to make sure that herpes is present, and not another disease that has similar clinical manifestations.

What can cause disease

The virus can enter the human body and develop in it, causing various manifestations such as itching, small blisters that turn into ulcers under certain conditions. At the current time, doctors involved in the diagnosis and subsequent treatment of herpes in the oral cavity claim that the following factors and conditions can provoke the appearance of the disease:

• situations causing emotional or physical stress;
• previous surgeries;
• colds;
• the patient has a fever;
• sunny, windy or cold weather;
• lack of sleep;
• period of menstruation in women;
• weakening of the immune system, known as immunosuppression.

The origin and subsequent development of infectious processes can be caused by one or several factors at once. It is worth noting that children are more susceptible to the development of herpes in the oral cavity, according to statistics from world experts.

Herpes in the mouth of a child

Before proceeding with the treatment of this disease, it is worthwhile to clearly understand at what stage of development it is. This will help determine how quickly the patient can get rid of the unpleasant manifestations of the development of herpes virus type 1 cells.

How the virus develops in the patient’s body

Penetrating into the human body, the herpes virus, both in a child and in an adult, moves to the accumulation of cells in the brain along the trigeminal nerve. Having reached the place known in science as the trigeminal ganglion, the viral cells fall into a dormant state until the moment of activation. After that, herpes goes back from the brain to the oral cavity. It is there that the formation of ulcers occurs, which are the main manifestation of the activity of viral cells.

The development of the disease from the appearance to the complete disappearance of ulcerative lesions occurs through six successive stages, namely:

• Harbinger stage. In this phase of development, sensations of tingling, itching and tingling appear.
• During the second stage swelling and redness appear. Painful sensations begin to arise, making it difficult to take food.
• In the third stage, one or more fluid-filled vesicles appear at the site of the lesion.
• After the blisters burst, yellowish ulcers appear in their place.
• The fifth stage is characterized by the formation of a fragmentary hard crust. The formed crust is not solid, it has cracks. There may be minor bleeding at the site of drying of the ulcers.
• During the last stage, the affected areas gradually disappear without leaving scars. The disappearance of ulcers is accompanied by mild swelling and redness.

In total, all six stages of the virus development take from one to two weeks without treatment.

It is worth remembering that herpes, which appeared in the oral cavity, can be confused with stomatitis. Their main difference is that stomatitis initially manifests itself in the form of ulcers in an active form, while herpes develops gradually to the degree of ulcers.

What drugs can be used to treat herpes

It is not at all necessary to treat herpes on the gums if the patient has everything in order with the immune system, and he does not belong to risk groups. You can simply alleviate the symptomatic manifestations of the infection. However, it is still much better to use pharmacy preparations that are easy to use and are available both with a prescription and without it.

Symptoms can be lessened by applying ice to diseased areas, or by moistening with lip balms or alcoholic beverages.

Cold sores on the lips can be stopped or prevented with the help of special creams, which can be purchased at any pharmacy. The most effective agents in the treatment of the herpes virus are docosanol and penciclovir. The first one can be easily bought without presenting a prescription. These drugs can be found on pharmacy shelves under the names “Abreva” and “Denavir”.

Abreva and Denavir for herpes

For those patients who suffer from immunosuppression or who are at risk according to the opinion of the attending physician, medications with antiviral effects can be used to treat this disease process. You can cure herpes with the help of such drugs by taking them orally. This group of medicines is prescribed for those patients who have frequent outbreaks of this virus.

Answering the question of how to treat herpes, doctors also often say that you can use drugs that have a local anesthetic effect, such as lidocaine and kaopektat. They are often used to protect the gums and palate. Painkillers may also help.

Conclusion

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