Alcohol and tylenol pm: Tylenol PM and Alcohol/Food Interactions
Tylenol PM and Alcohol/Food Interactions
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There are 2 alcohol/food/lifestyle interactions with Tylenol PM (acetaminophen / diphenhydramine).
Ask your doctor before using acetaminophen together with ethanol. This can cause serious side effects that affect your liver. Call your doctor immediately if you experience a fever, chills, joint pain or swelling, excessive tiredness or weakness, unusual bleeding or bruising, skin rash or itching, loss of appetite, nausea, vomiting, or yellowing of the skin or the whites of your eyes. If your doctor does prescribe these medications together, you may need a dose adjustment or special tests to safely take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
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Ask your doctor before using diphenhydrAMINE together with ethanol.
Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking diphenhydrAMINE. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
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Tylenol PM drug interactions
There are 500 drug interactions with Tylenol PM (acetaminophen / diphenhydramine).
Tylenol PM disease interactions
There are 11 disease interactions with Tylenol PM (acetaminophen / diphenhydramine) which include:
- alcoholism
- liver disease
- depression
- PKU
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
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More about Tylenol PM (acetaminophen / diphenhydramine)
- Tylenol PM consumer information
- Check interactions
- Compare alternatives
- Reviews (36)
- Drug images
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- Dosage information
- During pregnancy
- Support group
- Drug class: analgesic combinations
- En español
Related treatment guides
- Headache
- Insomnia
- Pain
Drug Interaction Classification
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
|---|---|
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
| Unknown | No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medical Disclaimer
Can You Take Tylenol with Alcohol?
Alcohol and acetaminophen — the active ingredient of Tylenol — can negatively affect the liver when taken on their own. When they are mixed, however, the synergistic effect they have on the liver multiplies the potential damage4 that they can cause.
Alcohol alone can put a significant strain on the liver. Many types of drugs should not be taken with alcohol because of potential negative interactions, many of which affect the liver.
Ultimately, mixing any substance with alcohol is not recommended unless you first consult with your doctor about potential drug interactions and effects.
What Is Tylenol?
Tylenol is a brand name for the generic drug acetaminophen. Acetaminophen is a pain reliever that can also help to reduce fevers. Some types of Tylenol may include other drugs as part of its formulation — for example, Tylenol PM is a combination of acetaminophen and diphenhydramine.
There are also drugs that contain acetaminophen but are not labeled as Tylenol. Regardless, any drug containing acetaminophen should generally not be mixed with alcohol.
Acetaminophen Side Effects
Acetaminophen use can lead to liver damage, even when alcohol is not used. This is rare in healthy individuals who follow acetaminophen dosage instructions. However, it may occur in people who take acetaminophen in excess or have certain underlying health conditions, especially ones affecting the liver.
Side effects with acetaminophen3 are uncommon, but they may include:
- Nausea
- Stomach pain
- Itching
- Dark urine
- Yellowing of the skin
- Decreased appetite
- Headache
If you are having side effects with acetaminophen, it is a good idea to consult with your doctor.
These effects can sometimes indicate liver damage.
Related Topic: Why Does Alcohol Make You Pee?
Tylenol and Alcohol Interaction
Tylenol and alcohol are both foreign chemicals to the body, and the body breaks down both of these chemicals by using the liver. While each substance individually puts some strain on the liver, the strain multiplies when both are used together. This makes it harder for the liver to break down these substances, which causes higher levels of each substance to remain in the liver. This can potentially lead to irreversible liver damage4.
While light drinking paired with normal Tylenol use may not have a large effect, someone who is using too much Tylenol or drinking heavily or frequently may experience more significant liver problems.
Effects of Alcohol and Tylenol
Liver damage is normally permanent, and the only way to cure it is to get a liver transplant. Some of the symptoms of liver damage include:
- Yellowing of the skin or whites of the eyes
- Confusion
- Ulcers
- Changes in stool color
- Bleeding or bruising easily
- Swelling in the legs and feet
- Swelling in the abdomen
- Itchy skin
- Dark urine
- Fatigue
- Nausea and vomiting
If you are having any of these symptoms, especially after using alcohol and Tylenol together, then you should see a doctor.
These can indicate that liver damage from alcohol has occurred and that you will need medical care.
Alternatives to Acetaminophen
Tylenol is one of two common types of over-the-counter (OTC) pain medications. The other major type of OTC pain medication is non-steroidal anti-inflammatory drugs (NSAIDs). This class of drug includes Aleve, ibuprofen and aspirin. These drugs are normally safer to use with alcohol, but they may cause gastrointestinal discomfort or even bleeding in those with a history of gastrointestinal bleeding. There are also prescription pain medications that may be safer to use with alcohol.
Ultimately, you should always consult with your doctor before using any medication at the same time as alcohol.
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FAQs
How long after taking Tylenol can I drink alcohol?
You should consult with a doctor to see what is best in your specific situation, but in most cases, it may be safe to take Tylenol 24 hours or more after using alcohol.
Can you take Tylenol with alcohol?
A healthy person may be able to safely use Tylenol1 while drinking lightly and infrequently, but even then, safety is not guaranteed. Typically, mixing Tylenol and alcohol should be avoided unless instructed by a doctor.
Does Tylenol interact with alcohol?
Tylenol and alcohol do not necessarily interact with each other; instead, they both act on the liver. This is what creates the negative effect of combining the two substances.
Tylenol™ – instructions for use, doses, side effects, reviews of the drug:
0.056 ‰
Analogs
All forms of release, dosages, registration certificates, drug manufacturers, drug characteristics
Product Description Tylenol™ Caplets (caplets), 500 mg) based on the label, approved by the manufacturer in 2000
Approval date: 07/31/2000
Content
- Active substance
- ATX
- Pharmacological group
- Nosological classification (ICD-10)
- Composition and form of release
- pharmachologic effect
- pharmachologic effect
- Indications
- Contraindications
- Use during pregnancy and lactation
- Dosage and administration
- Side effects
- Precautionary measures
- Storage conditions
- Best before date
- Reviews
Active ingredient
Paracetamol* (Paracetamol*)
ATX
N02BE01 Paracetamol
Pharmacological group
Anilides
Nosological classification (ICD-10)
ICD-10 code list
Composition and formulation
1 caplet contains paracetamol 500 mg; in a blister 10 pcs.
, in a box 1 blister or in strips of 2 pcs., in a box 50 strips.
Pharmacological action
Pharmacological action –
analgesic , antipyretic .
Inhibits cyclooxygenase, inhibits the synthesis of PG in the central nervous system and their stimulating effect on the thermoregulatory center of the hypothalamus; increases heat transfer.
Inhibits cyclooxygenase, inhibits the synthesis of PG in the central nervous system and their stimulating effect on the thermoregulatory center of the hypothalamus; increases heat transfer.
Indications
Pain of mild to moderate intensity (including headache, toothache, sore throat and general malaise), fever.
Contraindications
Hypersensitivity, severe impairment of liver and kidney function, deficiency of glucose−6-phosphate dehydrogenase, children’s age (up to 12 years).
Use during pregnancy and lactation
Acceptable, but only on medical prescription.
Dosage and Administration
Information for healthcare professionals only.
Are you a healthcare professional?
Inside, 2 caplets 3-4 times a day, but not more than 8 caplets per day.
Side effects
In rare cases, nausea, abdominal pain, allergic reactions (skin rash, itching, urticaria).
Precautions
Do not use more than 10 days for pain and 3 days as an antipyretic. It should not be taken together with other drugs containing paracetamol.
Storage conditions
At a temperature of 15–30 °C.
Keep out of reach of children.
Expiry date
4 years.
Do not use after the expiry date which is stated on the pack.
Update date: 11/21/2018
Reviews
Read all reviews and leave your own.
Information for healthcare professionals only.
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Tylenol PM | 59 factors
66 points
Tylenol PM
Tylenol PM
Why is Tylenol PM better than others?
- Paracetamol?
500mg vs 175.
77mg - Tablets per pack?
100 vs 44.37 - Dosage period?
14 vs 7.75 - Shelf life?
36months vs 31.6months - Diphenhydramine?
25mg vs 0.48mg
77mg Tylenol PM
vs
Tylenol Extra Strength
Tylenol PM
vs
Tylenol Regular Strength
Tylenol PM
vs
Tylenol Arthritis Pain
Tylenol PM
vs
Tempra Infant Drops
Tylenol PM
vs
Panadol Night
Tylenol PM
vs
Excedrin PM
Tylenol PM
vs
Aleve GelCaps
Tylenol PM
90 002 vs
Tylenol Sinus Congestion & Pain Severe
Tylenol PM
vs
Motrin PM
Tylenol PM
vs
Advil
9001 9 Composition
ibuprofen
Ibuprofen is a non-steroidal anti-inflammatory drug. The analgesic effect of ibuprofen takes effect immediately, however, the anti-inflammatory effects can last up to a week.
paracetamol
Paracetamol (acetaminophen in the US) is classified as a mild analgesic. It suppresses the feeling of pain, but does not treat the cause.
aspirin
Aspirin can be used as an analgesic, antipyretic and anti-inflammatory agent.
caffeine
Studies have shown that caffeine can increase the effectiveness of many analgesics, resulting in better, faster pain relief.
codeine
Codeine is an opiate used to treat mild to moderate pain. Opioids can change mood, sometimes resulting in a feeling of euphoria. It may be helpful in relieving pain, but addiction and withdrawal symptoms may occur.
Has more than one active ingredient
✔Tylenol PM
Product contains more than one active ingredient. These combinations usually complement each other, and sometimes one ingredient can enhance the effectiveness of another.
naproxin
Naproxen is an anti-inflammatory that can be used to treat a variety of pain symptoms.
Effects
Toothache
✔Tylenol PM
Toothache is pain in and around the teeth and jaw, often caused by caries.
Anti-Inflammatory
✖Tylenol PM
Anti-inflammatory drugs are especially good for muscle and joint pain as they not only block the pain, but also treat the cause.
Antipyretic (reduces body temperature)
✔Tylenol PM
Antipyretic drugs help to reduce body temperature. This helps patients feel better, however, this is not always recommended as fever may be a natural defense against infections.
Rheumatic pain
✖Tylenol PM
Rheumatic pain is pain in the joints and connective tissue, most commonly caused by arthritis.
Muscle pain
✔Tylenol PM
Muscle pain can be caused by exercise or other stress, and infections such as the flu.
Migraine
✔ Tylenol PM
Migraine is a very severe headache often accompanied by other symptoms such as flickering light, blind spots, tingling and sensitivity to light.