What are the ingredients in BENADRYL®? What is the active ingredient in BENADRYL®? Find out all the details about the ingredients in BENADRYL® and how they work.

The Active Ingredient in BENADRYL®

The active ingredient in BENADRYL® is an antihistamine called diphenhydramine HCl. Antihistamines are used to provide relief from symptoms related to hay fever, upper respiratory allergies, or the common cold.

Other Ingredients in BENADRYL®

In addition to the active ingredient, BENADRYL® contains several other ingredients that serve various purposes:

• Carnauba Wax: Gives the tablets their shiny appearance.
• Croscarmellose Sodium NF: Helps break down the tablet in your stomach.
• D&C Red No. 27 Aluminum Lake: Provides the nice color.
• Dibasic Calcium Phosphate: Helps hold the tablet together.
• Hypromellose: Helps mask the bitter taste.
• Magnesium Stearate: Coats the ingredients and prevents them from sticking to each other and to other things.
• Microcrystalline Cellulose NF (Avicel PH-102): Helps hold the tablet together.
• Polyethylene Glycol: Helps maintain the flexibility and structure of the tablet coating.
• Polysorbate 80: Helps incorporate the coating ingredients to make them uniform.
• Titanium dioxide: Creates a bright white coating.

Ingredients in Children’s BENADRYL®

The children’s formulation of BENADRYL® contains some additional ingredients to improve the taste and consistency of the product:

• Anhydrous citric acid: Helps keep the product stable and improves flavor.
• Carboxymethylcellulose Sodium: Thickens to improve the consistency of the product.
• Edetate disodium: Helps keep the product stable.
• D&C red no. 33, FD&C Blue no. 1, FD&C Red no. 40: Provide kid-friendly color.
• Flavors (Bubble Gum, Cherry): Improve the flavor of the product.
• Glycerin: Used to sweeten and help dissolve the active ingredient in the medicine.
• Monoammonium Glycyrrhizinate MM 100P: Used to improve flavor by blocking bitterness.
• Poloxamer 407 NF: Thickens to improve the consistency of the product.
• Saccharin Sodium: Provides sweetness to improve taste and flavor.
• Sodium Chloride USP: Helps keep the product stable and improves flavor.
• Sodium Citrate, Sodium Citrate Dihydrate: Help keep the product stable.
• Sodium Benzoate: Helps keep the product stable.
• Sorbitol Solution: Provides hydration and sweetness to improve the flavor.
• Sucralose: Provides sweetness and blocks bitterness of the active ingredient to improve the flavor.
• Sucrose: Provides sweetness to improve the flavor.

Topical BENADRYL® Ingredients

The topical formulation of BENADRYL® contains a different set of ingredients to provide skin relief:

• Alcohol
• Camphor
• Cetyl alcohol
• Citric acid
• Diazolidinyl urea
• Glycerin
• Methylparaben
• Polyethylene glycol monostearate 1000
• Povidone
• Propylene glycol
• Propylparaben
• SD alcohol 38-B
• Sodium citrate
• Tromethamines

Related BENADRYL® Products

In addition to the standard BENADRYL® formulation, there are also some related BENADRYL® products available:

• BENADRYL® Extra Strength Allergy Relief Antihistamine Tablets: Contains 50 mg of diphenhydramine HCl.
• BENADRYL® Allergy ULTRATABS® Tablets: Contains 25 mg of diphenhydramine HCl.
• BENADRYL® Itch Stopping Cream: A topical analgesic for skin relief.

How BENADRYL® Works

Diphenhydramine, the active ingredient in BENADRYL®, works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction. Its drying effects on symptoms like watery eyes and runny nose are caused by blocking another natural substance made by your body (acetylcholine).

BENADRYL® can be used to relieve symptoms of allergy, hay fever, and the common cold, including rash, itching, watery eyes, itchy eyes/nose/throat, cough, runny nose, and sneezing. It can also be used to prevent and treat nausea, vomiting, and dizziness caused by motion sickness. Diphenhydramine can also help you relax and fall asleep.

It’s important to follow all dosage directions carefully, as cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. These products do not cure or shorten the length of the common cold and may cause serious side effects.

Conclusion

BENADRYL® contains a variety of ingredients, both active and inactive, that work together to provide relief from allergy, cold, and other symptoms. Understanding the different components and how they function can help you use BENADRYL® products effectively and safely.

BENADRYL® Ingredients List | BENADRYL®

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Active Ingredient: Diphenhydramine HCl

The active ingredient in BENADRYL® is an antihistamine called diphenhydramine HCl. Antihistamines are used for relief from symptoms related to hay fever, upper respiratory allergy, or the common cold .

MORE ABOUT DIPHENHYDRAMINE HCL

BENADRYL® Ingredients

Carnauba Wax

Gives the tablets their shine

Croscarmellose Sodium NF

Helps break down the tablet in your stomach

D&C Red No. 27 Aluminum Lake

Provides nice color

Dibasic Calcium Phosphate

Helps hold the tablet together

Hypromellose

Helps mask bitter taste

Magnesium stearate

Coats ingredients and helps prevent them from sticking to each other and to other things

Microcrystalline Cellulose NF (Avicel PH-102)

Helps hold the tablet together

Polyethylene Glycol

Helps maintain the flexibility and structure of the tablet coating

Polysorbate 80

Helps incorporate the coating ingredients to make them uniform

Titanium dioxide

Creates a bright white coating

Children’s BENADRYL® Ingredients

Anhydrous citric acid

Helps keep the product stable and improves flavor

Carboxymethylcellulose Sodium

Thickens to improve the consistency of the product

Edetate disodium

Helps keep the product stable

D&C red no.

33

Provides kid friendly color

FD&C Blue no.1

Provides kid friendly color

FD&C Red no. 40

Provides kid friendly color

Flavors (Bubble Gum)

Improves the flavor of the product

Flavors (Cherry)

Improves the flavor of the product

Glycerin

Used to sweeten and help dissolve the active ingredient in medicine

Monoammonium Glycyrrhizinate MM 100P

Used to improve flavor by blocking bitterness

Poloxamer 407 NF

Thickens to improve the consistency of the product

Purified water

Acts as a base for our products

Saccharin Sodium

Provides sweetness to improve taste and flavor

Sodium Chloride USP

Helps keep product stable and improves flavor

Sodium Citrate

Helps keep product stable

Sodium Citrate Dihydrate

Helps keep product stable

Sodium Benzoate

Helps keep the product stable

Sorbitol Solution

Provides hydration and sweetness to improve the flavor

Sucralose

Provides sweetness and blocks bitterness of the active ingredient to improve the flavor

Sucrose

Provides sweetness to improve the flavor

Other Children’s Benadryl® Ingredients

Crospovidone, D&C red no. 30 aluminum lake, D&C red no.7 calcium lake, dextrose excipient, ethylcellulose, gum arabic, sugar spheres, and tartaric acid

Topical BENADRYL® Ingredients

Alcohol, camphor, cetyl alcohol, citric acid, diazolidinyl urea, glycerin, methylparaben, polyethylene glycol monostearate 1000, povidone, propylene glycol, propylparaben, SD alcohol 38-B, sodium citrate, and tromethamine

Related Products

BENADRYL® Extra Strength Allergy Relief Antihistamine Tablets with 50 mg of Diphenhydramine HCl

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BENADRYL® Allergy ULTRATABS® Tablets with Allergy Relief and Diphenhydramine HCI 25 mg

Ages&nbsp

Original Strength BENADRYL® Itch Stopping Cream Topical Analgesic for Skin Relief

Ages&nbsp

Benadryl Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Uses

Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes/nose/throat, cough, runny nose, and sneezing. It is also used to prevent and treat nausea, vomiting and dizziness caused by motion sickness. Diphenhydramine can also be used to help you relax and fall asleep.This medication works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction. Its drying effects on such symptoms as watery eyes and runny nose are caused by blocking another natural substance made by your body (acetylcholine).Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Do not use this product to treat cold symptoms in children younger than 6 years unless specifically directed by the doctor. Some products (such as long-acting tablets/capsules) are not recommended for use in children younger than 12 years. Ask your doctor or pharmacist for more details about using your product safely.These products do not cure or shorten the length of the common cold and may cause serious side effects. To decrease the risk for serious side effects, carefully follow all dosage directions. Do not use this product to make a child sleepy. Do not give other cough-and-cold medication that might contain the same or similar ingredients (see also Drug Interactions section). Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray).

How to use Benadryl

Follow all directions on the product package. If your doctor has prescribed this medication, take it as directed. If you have any questions, ask your doctor or pharmacist.

Take the tablet, capsule, or liquid form by mouth with or without food. Measure liquid forms of this medication using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. If you have a single-dose form of this medication (such as a single-use whistle), you do not need to measure the dose.

The rapidly-dissolving tablet or strip should be allowed to dissolve on the tongue and then swallowed, with or without water. The chewable tablets should be chewed thoroughly before being swallowed.

The dosage is based on your age, medical condition, and response to treatment. There are many brands and forms of diphenhydramine available. Read the dosing instructions carefully for each product because the amount of diphenhydramine may be different between products. Do not increase your dose or take this medication more often than directed.

To prevent motion sickness, take your dose 30 minutes before starting activity such as travel. To help you sleep, take your dose about 30 minutes before bedtime. If you continue to have difficulty sleeping for longer than 2 weeks, contact your doctor.

Tell your doctor if your condition does not improve or if it worsens.

Side Effects

Drowsiness, dizziness, constipation, stomach upset, blurred vision, or dry mouth/nose/throat may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

To relieve dry mouth, suck (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or use a saliva substitute.

If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: mental/mood changes (such as restlessness, confusion), difficulty urinating, fast/irregular heartbeat.

Get medical help right away if you have any very serious side effects, including: seizures.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking diphenhydramine, tell your doctor or pharmacist if you are allergic to it; or to dimenhydrinate; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: breathing problems (such as asthma, emphysema), high pressure in the eye (glaucoma), heart problems, high blood pressure, liver disease, seizures, stomach/intestine problems (such as ulcers, blockage), overactive thyroid (hyperthyroidism), difficulty urinating (for example, due to enlarged prostate).

This drug may make you dizzy or drowsy or blur your vision. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Liquid products, chewable tablets, or dissolving tablets/strips may contain sugar and/or aspartame. Liquid products may also contain alcohol. Caution is advised if you have diabetes, liver disease, phenylketonuria (PKU), or any other condition that requires you to limit/avoid these substances in your diet. Ask your doctor or pharmacist about using this product safely.

Children may be more sensitive to the side effects of this drug. This drug can often cause excitement in young children instead of drowsiness.

Older adults may be more sensitive to the side effects of this drug, especially drowsiness, dizziness, confusion, constipation, or trouble urinating. Drowsiness, dizziness, and confusion can increase the risk of falling.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

This drug passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

Some products that may interact with this drug include: antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray).

Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana (cannabis), drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or other antihistamines (such as cetirizine, chlorpheniramine).

Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

This medication may interfere with certain lab tests (such as allergy skin test), possibly causing false test results. Make sure lab personnel and all your doctors know you use this drug.

Does Benadryl interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe drowsiness, seizures, widened pupils. In children, mental/mood changes (such as restlessness, irritability, hallucinations) may occur before drowsiness.

Keep all medical and lab appointments.

If you miss a dose, take it as soon as you remember. If it is near the time of your next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Store at room temperature away from moisture and light. Do not store in the bathroom. Do not freeze liquid forms of this medication. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Images

Benadryl 25 mg capsule

Color: light yellowShape: oblongImprint: Benadryl

This medicine is a light yellow, oblong, translucent, capsule imprinted with “Benadryl”.

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

TikTok challenge will be banned in Russia: all because of a drug

Society kTok. This applies to videos with the hashtag #benadryl. In fact, this inscription is not as harmless as it seems. The authors of the videos urge people to take the drug for allergies in large quantities to cause hallucinations. We talk about the challenge in which you do not need to participate.

Roskomnadzor will block content on the TikTok social network in Russia. This happened after it became known that in the United States, teenagers launched a challenge, the essence of which is to take large doses of an allergy drug called Benadryl to cause hallucinations. Member of the State Duma Committee on Health Boris Mendelevich appealed to the department with a request, if possible, to remove this kind of content from Runet.

Roskomnadzor responded to Mendelevich’s appeal, found 20 TikTok channels where videos of this kind are posted. If the department finds more videos, it will block them as well.

Not only Mendelevich and Roskomnadzor considered the content dangerous, but also Rosmolodezh. “The videos on the above links pose a threat to the life and health of minors,” the organization’s letter says, RIA Novosti reports.

Crazy Challenge

Tiktokers named the challenge #Benadryl. As part of this competition, users drink the allergy medicine Benadryl in large quantities to induce hallucinations. Videos with the hashtag #Benadryl on TikTok gained about 5.5 million views at the end of July, and by the end of August the number of users interested in this topic had increased to six million.

“I see people in my room after taking Benadryl.”

This challenge does have negative consequences. At least three teenagers were sent to the hospital in May. All ended up at the Cook Children’s Medical Center. The doctors of the institution emphasized that Benadryl is a dangerous drug, an overdose of which is dangerous and can even lead to death. This despite the fact that the drug is sold for some reason without a prescription.

“Excessive amounts of diphenhydramine (the active ingredient in Benadryl — ed. note) can cause heart palpitations and arrhythmias, as well as hallucinations and convulsions. In addition, an overdose can cause urinary retention, so treatment may require a urinary catheter,” said Nurse Amber Jevison.

Among the victims of Benadryl was 14-year-old blogger Rebecca. She took 14 tablets of the drug. The girl began to hallucinate, her speech became abrupt, and her pulse rose to 199 beats per minute (against the norm of 65 to 90).

Someone even thought of giving the drug to a dog. And this effect followed after five minutes.

Benadryl has a whole list of side effects due to a substance called diphenhydramine. In addition to a crazy increase in heart rate, the drug causes difficulty urinating, uncontrolled movement of the tongue, swelling of the face, lips, throat, shortness of breath, confusion, dizziness, drowsiness (due to effects on the central nervous system), loss of coordination, dry mouth, stomach upset, dry eyes, blurred vision, hangover feeling. And this is only a part of those negative phenomena that can occur when taking Benadryl.

Authors:

Boris Lomakin

Medicines

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Benadryl for dogs and cats

9 0049 11/09/2022 Medications507

Information about the drug

• Name of the drug: Benadryl for dogs and cats
• Generic name: Benadryl®
• Type of drug: antihistamine
• Used for: allergies, inhalation allergies, motion sickness in dogs, irritability.
• Species: Dogs, Cats
• Distribution: OTC
• Available forms: 25 mg and 50 mg capsules, 12.5 and 50 mg tablets, oral liquid, injection.

General Description

Benadryl® is an antihistamine commonly used by both humans and pets. It is used to treat many symptoms, including allergies and motion sickness. It does not treat the underlying problems causing these symptoms.

Can I give my cat or dog Benadryl ® ?

Yes, but you should only give this drug to a cat or dog on the advice of a veterinarian.

How much Benadryl can be given to a cat or dog?

Benadryl® osages for dogs and cats vary. You should always check with your veterinarian before giving this medication to your pet for the correct dosage.

How it works

Antihistamines work by counteracting histamine, a chemical that causes inflammation and itching as part of an allergic reaction.

Diphenhydramine works by blocking the H-1 receptors that occur on small blood vessels and smooth muscles.

When histamine attaches to these receptors, it causes these vessels to dilate, causing inflammation and itching, and the muscles around the airways to contract, making breathing difficult.

The anti-motion sickness property of Benadryl® works by blocking impulses to the vomiting center in the brain. It is only effective in dogs.

Storage information

Store in a tightly closed container at room temperature.

What should I do if I miss my medication?

Give the missed dose as soon as possible.