Butalbital-APAP-Caffeine Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

Some products that may interact with this drug include: acetazolamide, darunavir, dichlorphenamide, ketorolac, lithium, 6-mercaptopurine, methotrexate, methoxyflurane, mifepristone, phenytoin, sodium oxybate, certain antibiotics (including penicillin, sulfonamides such as sulfamethoxazole), certain drugs used to treat gout (including uricosuric drugs such as probenecid, sulfinpyrazone).

This medication may increase the risk of bleeding when taken with other drugs that also may cause bleeding. Examples include anti-platelet drugs such as clopidogrel, “blood thinners” such as dabigatran/enoxaparin/warfarin, among others.

This drug can speed up the removal of other drugs from your body by affecting certain liver enzymes. These affected drugs include doxycycline, estrogen, felodipine, lonafarnib, quinidine, rilpivirine, tamoxifen, theophylline, voriconazole, certain beta blockers (such as metoprolol), corticosteroids (such as prednisone), among others.

Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana (cannabis), other drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine).

Check the labels on all your medicines (allergy or cough-and-cold products, other headache medications) because they may contain aspirin, caffeine, or ingredients that cause drowsiness. Also keep in mind that certain beverages (such as coffee, colas, tea) contain caffeine. Ask your pharmacist about using those products safely.

Also, check all prescription and nonprescription medicine labels carefully since many medications contain pain relievers/fever reducers (NSAIDs such as ibuprofen, naproxen, aspirin) that may increase your risk for side effects if taken together with this medication. However, if your doctor has directed you to take low-dose aspirin to prevent heart attack or stroke (usually 81-162 milligrams a day), you should continue taking the aspirin unless your doctor instructs you otherwise. Ask your doctor or pharmacist for more details.

This medication may decrease the effectiveness of hormonal birth control such as pills, patch, or ring. This could cause pregnancy. Discuss with your doctor or pharmacist if you should use additional reliable birth control methods while using this medication. Also tell your doctor if you have any new spotting or breakthrough bleeding, because these may be signs that your birth control is not working well.

This medication may interfere with certain medical/laboratory tests (including fasting blood glucose, cholesterol levels, prothrombin time, urine 5-HIAA levels, urine VMA levels, certain urine glucose tests, dipyridamole-thallium imaging tests), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

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Acetaminophen, butalbital, and caffeine Uses, Side Effects & Warnings

Generic name: acetaminophen, butalbital, and caffeine [ a-SEET-a-MIN-oh-fen, bue-TAL-bi-tal, and-KAF-een ]
Brand names: Esgic, Fioricet, Zebutal, Esgic-Plus, Arcet,
… show all 37 brands
Isocet, Pharmagesic, Anoquan, Two-Dyne, Tenake, Margesic, Anolor 300, Femcet, Geone, Tencet, Triad, Fiorpap, Repan, Dolmar, Endolor, Ezol, Ide-cet, G-1, Medigesic, Minotal, Mygracet, Pacaps, Alagesic, Americet, Nonbac, Dolgic LQ, Dolgic Plus, Orbivan, Capacet, Vanatol LQ, Vanatol S, Vtol LQ

Dosage forms: oral capsule (300 mg-50 mg-40 mg; 325 mg-50 mg-40 mg), oral liquid (325 mg-50 mg-40 mg/15 mL), oral tablet (325 mg-50 mg-40 mg)
Drug class: Analgesic combinations

Medically reviewed by Drugs. com on Jan 21, 2022. Written by Cerner Multum.

What is acetaminophen, butalbital, and caffeine?

Acetaminophen is a pain reliever and fever reducer.

Butalbital is in a group of drugs called barbiturates. It relaxes muscle contractions involved in a tension headache.

Caffeine is a central nervous system stimulant. It relaxes muscle contractions in blood vessels to improve blood flow.

Acetaminophen, butalbital, and caffeine is a combination medicine used to treat tension headaches that are caused by muscle contractions.

Acetaminophen, butalbital, and caffeine may also be used for purposes not listed in this medication guide.

Warnings

Do not use this medcine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine.

Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death. Call your doctor at once if you have nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of your skin or eyes).

In rare cases, acetaminophen may cause a severe skin reaction. Stop taking acetaminophen, butalbital, and caffeine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.

Before taking this medicine

Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

You should not use acetaminophen, butalbital, and caffeine if you are allergic to it, if you have porphyria, or if you have recently used alcohol, sedatives, tranquilizers, or other opioids.

Tell your doctor if you have ever had:

• liver disease, cirrhosis, a history of alcoholism or drug addiction, or if you drink more than 3 alcoholic beverages per day;

• kidney disease;

• stomach ulcer or bleeding;

• a history of skin rash caused by any medication; or

• a history of mental illness or suicidal thoughts.

It is not known whether this medicine will harm an unborn baby. If you use butalbital while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant.

This medicine can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breastfeeding a baby.

Not approved for use by anyone younger than 12 years old.

How should I take acetaminophen, butalbital, and caffeine?

Follow all directions on your prescription label. Do not take more of this medication than recommended. An overdose can damage your liver or cause death. Tell your doctor if the medicine seems to stop working as well in relieving your pain.

Butalbital may be habit-forming. Never share acetaminophen, butalbital, and caffeine with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it. Selling or giving away this medicine is against the law.

Store at room temperature away from moisture and heat.

Keep track of the amount of medicine used from each new bottle. Butalbital is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

What happens if I miss a dose?

Since this medicine is used when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of acetaminophen, butalbital, and caffeine can be fatal.

The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.

Overdose symptoms may also include insomnia, restlessness, tremor, diarrhea, increased shallow breathing, uneven heartbeats, seizure (convulsions), or fainting.

What should I avoid while taking acetaminophen, butalbital, and caffeine?

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol. It may increase your risk of liver damage while taking acetaminophen.

Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP.

While you are taking this medication, avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor’s advice.

Acetaminophen, butalbital, and caffeine side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

In rare cases, acetaminophen may cause a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen in the past and had no reaction. Stop taking acetaminophen, butalbital, and caffeine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling. If you have this type of reaction, you should never again take any medicine that contains acetaminophen.

This medicine may cause serious side effects. Stop using this medicine and call your doctor at once if you have:

• confusion, a seizure;

• shortness of breath;

• a light-headed feeling, like you might pass out; or

• nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common side effects of acetaminophen, butalbital, and caffeine may include:

• drowsiness, dizziness;

• feeling light-headed;

• nausea, vomiting, stomach pain;

• drunk feeling; or

• shortness of breath.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Acetaminophen, butalbital, and caffeine dosing information

Usual Adult Dose for Headache:

Butalbital 50 mg/acetaminophen 300 mg/caffeine 40 mg: 1 or 2 capsules orally every 4 hours as needed not to exceed 6 capsules per day

Butalbital 50 mg/acetaminophen 325 mg/caffeine 40 mg: 1 or 2 capsules or tablets orally every 4 hours as needed not to exceed 6 capsules or tablets per day

Butalbital 50 mg/acetaminophen 325 mg/caffeine per 15 mL oral liquid: 15 to 30 mL orally every 4 hours as needed not to exceed 90 mL per day

Comments:
-Due to high rate of physical dependence, the extended use of this drug is not recommended.
-The safety and efficacy of treating multiple recurrent headaches with this product is not known.

Uses: For the relief of the symptom complex of tension (or muscle contraction) headache.

Usual Pediatric Dose for Headache:

12 years or older:

Butalbital 50 mg/acetaminophen 300 mg/caffeine 40 mg: 1 or 2 capsules orally every 4 hours as needed not to exceed 6 capsules per day

Butalbital 50 mg/acetaminophen 325 mg/caffeine 40 mg: 1 or 2 capsules or tablets orally every 4 hours as needed not to exceed 6 capsules or tablets per day

Butalbital 50 mg/acetaminophen 325 mg/caffeine per 15 mL oral liquid: 15 to 30 mL orally every 4 hours as needed not to exceed 90 mL per day

Comments:
-Due to high rate of physical dependence, the extended use of this drug is not recommended.
-The safety and efficacy of treating multiple recurrent headaches with this product is not known.

Uses: For the relief of the symptom complex of tension (or muscle contraction) headache.

What other drugs will affect acetaminophen, butalbital, and caffeine?

Taking this medicine with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before taking acetaminophen, butalbital, and caffeine with a sleeping pill, opioid pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.

Other drugs may affect acetaminophen, butalbital, and caffeine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

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Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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The story of one thing: baseball cap –

baseball cap
history

11/26/2015, 11:49

The holistic perception of the image and its charm always consists of many small details, the selection and combination of which is determined by a sense of style and individual taste.

Every modern person, leading an active lifestyle and occupying a certain social niche, strives to have his own image that will reflect his views, help him express himself and promote success. After all, each person is special in his own way, therefore, his style is unique.

Such uniqueness and personal originality is achieved by combining certain things. But the final completeness of the image and additional “zest”, of course, give accessories.

A stylish and practical accessory that almost everyone wears today is the baseball cap. It not only protects from the sun or light cold, but also piquantly complements the image. Recently, a variety of types of baseball caps have appeared: from warm “winter” caps to the most unusual designer models. And once it was an element of only sports ammunition! How did it happen that the bey cap became such a popular headdress and who first put it on their heads?

The history of this headdress can be guessed from its name. In the middle of the 20th century, it was an important element of sportswear for baseball players. The first standard baseball cap was called “59Fifty” and was released by the American company “New Era”. The classic baseball cap was inspired by jockey helmets (they took shape) and work beanie caps (one sewing technique, “petals connected at the top with a button).

It was very comfortable to wear a baseball cap under the scorching sun: it protected the head from overheating, and the visor prevented the sun from blinding the eyes. Plus, each team had their own branded baseball caps, which supported their overall team style. The first lucky ones to have their heads covered with baseball caps were members of the Brooklyn Excelsiors team in Brooklyn, in connection with which, wearing this hat with a long visor has acquired the name “Brooklyn-style”.

Soon, which is quite logical, baseball players were followed by their fans: in the 1970s and 1980s, sports fans began to actively wear baseball caps to emphasize their respect and passion for one or another baseball team. Now this headgear has also become the equipment of fan clubs.

A little later, the baseball cap found its niche as a part of corporate style, becoming part of the branded clothing of employees of many companies (for example, fast food cafes). In this case, the baseball cap also acted as an advertising medium. And soon the baseball cap became very popular among all the inhabitants of Europe.

So, as is always the case with the rise in popularity, the baseball cap began to change. Initially, baseball caps were produced in different sizes, but in the 80s a special clasp was developed, thanks to which buyers could independently adjust the size to fit their head. This made it possible to produce exactly the same baseball caps, which, of course, significantly simplified the process of their manufacture and increased productivity. The baseball cap is no longer a scarce commodity.

In Russia, this headdress appeared at the beginning of 90-s. But often, even now, baseball caps are confused with caps, believing that they are one and the same. Let’s figure out what the difference is.

The cap is a soft headgear with a soft small visor, without fastening at the back.

Baseball cap, on the other hand, has a rigid visor, which can be of different lengths and shapes, and a fastener at the back to adjust the size.

Modern baseball caps have a wide range of models. The following main types of baseball caps can be distinguished:

– “5-panel Cap”. Such a baseball cap is sewn from five parts: one in front, two on top and one part on the sides. The manufacturer’s logo usually flaunts in front, and there is a fastener for adjusting the size at the back. The visor of this model is straight and may differ in color or material from the main part of the baseball cap.

– “Needle Hat” or “needle hat”. In this case, six parts are used in the manufacture – “petals”, which gradually narrow from the base to the top and are connected with a special button. The peak has a curved shape, and it can also, together with the button, have a different color from the main part of the baseball cap. The company logo is printed on the front. This model can be both with a clasp and without it.

– “Bicycle Cap”. This model is designed for cycling and most of all resembles old baseball caps. The number of “petals” that make up a baseball cap can vary from 2 to 6. The main feature of the model is a very small visor, since a long visor can block the view and move under gusts of wind. There are no fasteners for this option and a thin fabric is used for sewing it, because an equally important headgear for a cyclist is a helmet, which should easily fit over a baseball cap.

– “Trucker Hat”, also known as a trucker’s cap. A very common summer version of a baseball cap. Its main feature is the presence of a plastic mesh, which replaces the rear “petals”. Also, this model is supplied with a clasp and has a fairly voluminous front part that covers the forehead.

– “Fitted Hat” or a straight visor. This is a favorite option for ardent fans of hip-hop culture. The main feature of the model is a straight wide visor and the absence of a fastener. Therefore, you need to select such a baseball cap based on the size ruler.

– “Field Cap / Patrol Cap”. This model is for military and hunters. Or for lovers of military style in clothes. It is sewn from four parts: two panels go in a semicircle, and the top and visor are flat. It does not have fasteners to adjust the size and is most often produced in camouflage or khaki colors.

– “Beanie” Perhaps the most unusual baseball cap model. It looks like a cap with a visor, but it is also sewn from “petals”, which are connected at the top of the cap with a button. The visor of this model is very small and there is no fastener to adjust the size.

In the manufacture of many models of baseball caps, special small holes, called eyelets, are used to ventilate the top of the head. The canvas of the eyelets can be metal, plastic or sheathed with threads. Also, fasteners can be made from different materials. All the seams of baseball caps are always hidden, the “petals” are sewn inside and often they are printed with the brand name.

Now the baseball cap is not just a headdress, but also an important part of the style of every fashionista. She became the true leader of headwear among people of all ages and gender.