Can 8 year old take 500mg tylenol. Comprehensive Guide to TYLENOL® Dosing: Ensuring Safe and Effective Pain Relief
How to properly dose TYLENOL for different age groups and formulations. What are the maximum daily dosages for various TYLENOL products. How to choose the right TYLENOL product for specific needs. When should you consult a healthcare professional about TYLENOL usage.
Understanding TYLENOL® Dosage Guidelines for Various Age Groups
TYLENOL®, containing the active ingredient acetaminophen, is a widely used over-the-counter pain reliever and fever reducer. Proper dosing is crucial for its safe and effective use. This comprehensive guide will help you navigate the dosage recommendations for different TYLENOL® formulations and age groups.
Adult Dosing for Regular Strength TYLENOL®
Regular Strength TYLENOL® products contain 325 mg of acetaminophen per dose. For adults and children 12 years and older, the recommended dosage is:
- 2 tablets or capsules every 4-6 hours while symptoms last
- Do not exceed 10 tablets or capsules in 24 hours, unless directed by a doctor
- Total labeled daily dose: 3250 mg/day
Does Regular Strength TYLENOL® have a different dosing schedule for liquid gels and tablets. No, the dosing recommendations are the same for both formulations.
Adult Dosing for Extra Strength TYLENOL®
Extra Strength TYLENOL® products contain 500 mg of acetaminophen per dose. For adults and children 12 years and older, the recommended dosage is:
- 2 caplets, tablets, or powders every 6 hours while symptoms last
- Do not exceed 6 caplets, tablets, or powders in 24 hours, unless directed by a doctor
- Total labeled daily dose: 3000 mg/day
Is there a difference in dosing between Extra Strength TYLENOL® caplets, coated tablets, and dissolve packs. No, the dosing recommendations are consistent across these formulations.
TYLENOL® Dosing for Children and Infants
Dosing TYLENOL® for children requires special attention to weight and age. The TYLENOL® Family, Children & Adults Oral Suspension is specifically formulated for easier dosing across various age groups.
Weight-Based Dosing Chart for Children’s TYLENOL®
Here’s a quick reference chart for dosing TYLENOL® Oral Suspension (160 mg/5 mL) based on a child’s weight:
- 24-35 lbs (2-3 years): 5 mL
- 36-47 lbs (4-5 years): 7.5 mL
- 48-59 lbs (6-8 years): 10 mL
- 60-71 lbs (9-10 years): 12.5 mL
- 72-95 lbs (11 years): 15 mL
- 96 lbs and over (12 years and older): 20 mL
Why is weight-based dosing preferred over age-based dosing for children. Weight-based dosing provides a more accurate dose based on the child’s body size, which can vary significantly even among children of the same age.
Important Considerations for Children’s TYLENOL® Dosing
When administering TYLENOL® to children, keep these crucial points in mind:
- Always use the dosing device provided with the medication
- Do not exceed 5 doses in 24 hours, unless directed by a doctor
- For children under 24 lbs or under 2 years of age, consult a doctor before use
- Take every 4 hours while symptoms last
Can you use adult TYLENOL® formulations for children under 12. It’s not recommended. Children’s formulations are specifically designed for easier and more accurate dosing based on a child’s weight.
Professional Discretionary Dosing and Safety Considerations
In 2011, the manufacturers of TYLENOL® implemented changes to enhance the safe use of acetaminophen. These changes affected the labeled maximum daily dose for single-ingredient TYLENOL® Extra Strength products sold in the US.
Changes in Maximum Daily Dose
The following adjustments were made to the labeled maximum daily dose:
- Reduced from 8 pills/day (4000 mg) to 6 pills/day (3000 mg)
- Changed dosage interval from 2 pills every 4-6 hours to 2 pills every 6 hours
Why were these changes implemented. The adjustments were made to help encourage the safe use of acetaminophen and reduce the risk of accidental overdose.
Healthcare Professional Discretion
While the labeled daily dose has been reduced, healthcare professionals may exercise their discretion in certain situations:
- If pain or fever persists at the total labeled daily dose, healthcare professionals may recommend up to 4000 mg/day
- The efficacy and safety of TYLENOL® at 4000 mg/day are well established
Should patients increase their TYLENOL® dosage without consulting a healthcare professional. No, patients should always follow the labeled instructions or consult with a healthcare professional before increasing their dosage.
Specialized TYLENOL® Formulations and Their Dosing Guidelines
TYLENOL® offers several specialized formulations designed to address specific needs. Understanding the proper dosing for these products is essential for their safe and effective use.
TYLENOL® 8HR Arthritis Pain Tablets
This extended-release formulation is designed to provide long-lasting relief for arthritis pain. The dosing guidelines are:
- Active ingredient: Acetaminophen 650 mg (extended-release)
- Dosage: 2 tablets every 8 hours
- Do not exceed 6 tablets in 24 hours
How does the extended-release formulation differ from regular TYLENOL®. The extended-release tablets are designed to provide pain relief for up to 8 hours, reducing the frequency of dosing compared to regular formulations.
TYLENOL® 8HR Muscle Aches & Pain Tablets
Similar to the Arthritis Pain formula, this product offers extended relief for muscle aches and pain. The dosing guidelines are identical to the Arthritis Pain tablets:
- Active ingredient: Acetaminophen 650 mg (extended-release)
- Dosage: 2 tablets every 8 hours
- Do not exceed 6 tablets in 24 hours
TYLENOL® PM Extra Strength Caplets
This nighttime formula combines pain relief with a sleep aid. The dosing guidelines are:
- Active ingredients: Acetaminophen 500 mg, Diphenhydramine HCl 25 mg
- Dosage: 2 caplets at bedtime
- Do not exceed 2 caplets in 24 hours
Is it safe to take TYLENOL® PM for extended periods. TYLENOL® PM should not be used for longer than 2 weeks without consulting a healthcare professional, as prolonged use of sleep aids may lead to dependence.
Importance of Reading Labels and Avoiding Double Dosing
With the variety of TYLENOL® products available, it’s crucial to read labels carefully and avoid unintentional double dosing.
Understanding Active Ingredients
Many over-the-counter and prescription medications contain acetaminophen as an active ingredient. To prevent accidental overdose, follow these guidelines:
- Always read the labels of all medications you’re taking
- Use ONLY one medicine containing acetaminophen at a time
- Be aware of common abbreviations for acetaminophen, such as APAP or paracetamol
Why is it dangerous to take multiple medications containing acetaminophen. Taking multiple acetaminophen-containing products simultaneously can lead to liver damage due to overdose, as you may unknowingly exceed the maximum safe daily limit.
Consulting Healthcare Professionals
In certain situations, it’s essential to consult a healthcare professional before using TYLENOL®:
- If you have liver disease or a history of alcohol abuse
- If you’re taking warfarin or other blood thinners
- If you’re pregnant or breastfeeding
- If symptoms persist or worsen after following the recommended dosage
When should you seek immediate medical attention while taking TYLENOL®. Seek immediate medical help if you experience signs of an allergic reaction (rash, itching, swelling) or symptoms of liver problems (nausea, upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice).
Proper Storage and Disposal of TYLENOL® Products
Ensuring the proper storage and disposal of TYLENOL® products is crucial for maintaining their effectiveness and preventing accidental ingestion or misuse.
Storage Guidelines
To maintain the quality and safety of TYLENOL® products, follow these storage recommendations:
- Store at room temperature, away from moisture and heat
- Keep the product in its original container with the label intact
- Ensure the cap is tightly closed after each use
- Keep out of reach of children and pets
How does improper storage affect TYLENOL® products. Exposure to heat, moisture, or light can degrade the active ingredients, potentially reducing the medication’s effectiveness or causing it to expire prematurely.
Safe Disposal Methods
When it’s time to dispose of expired or unused TYLENOL® products, follow these guidelines to ensure safety and environmental responsibility:
- Check for local medication take-back programs in your area
- If no take-back program is available, mix the medication with an undesirable substance (e.g., used coffee grounds or kitty litter) in a sealed plastic bag before disposing in household trash
- Remove or obscure all personal information on the empty container before disposing
- Do not flush medications down the toilet unless specifically instructed to do so
Why is it important to dispose of medications properly. Proper disposal prevents accidental ingestion by children or pets, reduces the risk of drug misuse, and minimizes environmental contamination.
Recognizing and Responding to Acetaminophen Overdose
While TYLENOL® is generally safe when used as directed, an overdose can occur if too much is taken or if it’s combined with other acetaminophen-containing products. Recognizing the signs of an overdose and knowing how to respond is crucial.
Signs and Symptoms of Acetaminophen Overdose
Be aware of the following potential signs of acetaminophen overdose:
- Nausea and vomiting
- Loss of appetite
- Sweating
- Extreme fatigue
- Abdominal pain, especially in the upper right area
- Yellowing of the skin or whites of the eyes (jaundice)
- Confusion or irritability
How quickly do symptoms of acetaminophen overdose appear. Initial symptoms may occur within hours of ingestion, but liver damage may not become apparent for 24 to 72 hours after the overdose.
Immediate Actions in Case of Suspected Overdose
If you suspect an acetaminophen overdose, take the following steps immediately:
- Call your local poison control center or emergency services immediately
- Do not induce vomiting unless instructed to do so by a medical professional
- Provide information about the amount ingested and the time of ingestion if possible
- Bring the medication container or remaining pills to the hospital
- Seek emergency medical attention even if no symptoms are present, as early treatment is critical
Why is early treatment crucial in cases of acetaminophen overdose. Early treatment with the antidote N-acetylcysteine can prevent or reduce liver damage, but its effectiveness decreases as time passes after the overdose.
Long-Term Effects and Prevention
Understanding the potential long-term effects of acetaminophen overdose can help emphasize the importance of proper usage:
- Severe liver damage or failure
- Need for liver transplantation in extreme cases
- Potential kidney damage
- Long-term health complications related to organ damage
To prevent accidental overdose, always follow these guidelines:
- Carefully read and follow dosing instructions on all medications
- Keep a log of all medications taken, including over-the-counter products
- Avoid alcohol consumption while taking acetaminophen
- Use a medication tracker app or pill organizer to prevent double dosing
- Educate family members about proper medication use and storage
How can healthcare providers help prevent acetaminophen overdose. Healthcare providers can educate patients about safe acetaminophen use, screen for potential drug interactions, and provide clear dosing instructions, especially for patients with chronic pain conditions.
TYLENOL® Dosing Guidelines | TYLENOL® Professional
Use these charts to guide proper dosage for your patients 12 and older
Jump to product:
- TYLENOL® Regular Strength Liquid Gels
- TYLENOL® Regular Strength Tablets
- TYLENOL® Family, Children & Adults Oral Suspension
- TYLENOL® Extra Strength Caplets
- TYLENOL® Extra Strength Coated Tablets
- TYLENOL® Extra Strength Dissolve Packs
- TYLENOL® Rapid Release Gels
- TYLENOL® 8HR Arthritis Pain Tablets
- TYLENOL® 8HR Muscle Aches & Pain Tablets
- TYLENOL® PM Extra Strength Caplets
Patients may have questions about over-the-counter analgesics. Use the information below to help them find the TYLENOL® product that’s right for them. Remember, many medicines contain the same active ingredient, so remind patients to use ONLY 1 medicine containing the same active ingredient at a time.
PROFESSIONAL DISCRETIONARY DOSING: To help encourage the safe use of acetaminophen, in 2011, the makers of TYLENOL® lowered the labeled maximum daily dose for single-ingredient TYLENOL® Extra Strength (acetaminophen) products sold in the US from 8 pills/day (4000 mg) to 6 pills/day (3000 mg). The dosage interval also changed from 2 pills every 4 to 6 hours to 2 pills every 6 hours. If pain or fever persists at the total labeled daily dose, healthcare professionals may exercise their discretion and recommend up to 4000 mg/day.*
*The efficacy and safety of TYLENOL® at 4000 mg/day are well established.
Regular Strength TYLENOL® Regular Strength Liquid Gels | |||
---|---|---|---|
ACTIVE INGREDIENT ACTIVE INGREDIENT, DOSAGE* & DIRECTIONS | DOSAGE FREQUENCY* | DIRECTIONS | |
Acetaminophen 325 mg (in each capsule) | 2 capsules every 4-6 hours while symptoms last | Not to exceed 10 capsules in 24 hours, unless directed by a doctor Total labeled daily dose: | |
*Consult TYLENOL® Regular Strength liquid gels packaging for dosing children under 12 years.
†The efficacy and safety of TYLENOL® at 4000 mg/day are well established.
Regular Strength TYLENOL® Regular Strength Tablets | |||
---|---|---|---|
ACTIVE INGREDIENT ACTIVE INGREDIENT, DOSAGE* & DIRECTIONS | DOSAGE FREQUENCY* | DIRECTIONS | |
Acetaminophen 325 mg (in each tablet) | 2 tablets every 4-6 hours while symptoms last | Not to exceed 10 tablets in 24 hours, unless directed by a doctor Total labeled daily dose: | |
*Consult TYLENOL® Regular Strength tablet packaging for dosing children under 12 years.
†The efficacy and safety of TYLENOL® at 4000 mg/day are well established.
TYLENOL® Family, Children & Adults Oral Suspension | |||
---|---|---|---|
ACTIVE INGREDIENT | DOSAGE FREQUENCY | DIRECTIONS | |
Acetaminophen 160 mg (in each 5 mL) | Take every 4 hours while symptoms last | Not to exceed 5 doses in 24 hours, unless directed by a doctor | |
IF POSSIBLE, USE WEIGHT TO DOSE; OTHERWISE, USE AGE. | |||
WEIGHT | AGE | DOSE* | |
Under 24 lbs | Under 2 years | Ask a doctor | |
24-35 lbs | 2-3 years | 5 mL | |
36-47 lbs | 4-5 years | 7.5 mL | |
48-59 lbs | 6-8 years | 10 mL | |
60-71 lbs | 9-10 years | 12.5 mL | |
72-95 lbs | 11 years | 15 mL | |
96 lbs and over | Adults and children 12 years and over | 20 mL | |
mL = milliliter
*Or as directed by a doctor.
†The efficacy and safety of TYLENOL® at 4000 mg/day are well established.
Extra Strength TYLENOL® Extra Strength Caplets | |||
---|---|---|---|
ACTIVE INGREDIENT ACTIVE INGREDIENT, DOSAGE* & DIRECTIONS | DOSAGE FREQUENCY* | DIRECTIONS | |
Acetaminophen 500 mg (in each caplet) | 2 caplets every 6 hours while symptoms last | Not to exceed 6 caplets in 24 hours, unless directed by a doctor Total labeled daily dose: | |
*For children under 12 years, at healthcare professional’s discretion.
†The efficacy and safety of TYLENOL® at 4000 mg/day are well established.
Extra Strength TYLENOL® Extra Strength Coated Tablets | |||
---|---|---|---|
ACTIVE INGREDIENT ACTIVE INGREDIENT, DOSAGE* & DIRECTIONS | DOSAGE FREQUENCY* | DIRECTIONS | |
Acetaminophen 500 mg (in each tablet) | 2 tablets every 6 hours while symptoms last | Not to exceed 6 tablets in 24 hours, unless directed by a doctor Total labeled daily dose: | |
*For children under 12 years, at healthcare professional’s discretion.
†The efficacy and safety of TYLENOL® at 4000 mg/day are well established.
Extra Strength TYLENOL® Extra Strength Dissolve Packs | |||
---|---|---|---|
ACTIVE INGREDIENT ACTIVE INGREDIENT, DOSAGE* & DIRECTIONS | DOSAGE FREQUENCY* | DIRECTIONS | |
Acetaminophen 500 mg (in each powder) | 2 powders every 6 hours while symptoms last | Not to exceed 6 powders in 24 hours, unless directed by a doctor Total labeled daily dose: | |
*For children under 12 years, at healthcare professional’s discretion.
†The efficacy and safety of TYLENOL® at 4000 mg/day are well established.
Extra Strength TYLENOL® Rapid Release Gels | |||
---|---|---|---|
ACTIVE INGREDIENT ACTIVE INGREDIENT, DOSAGE* & DIRECTIONS | DOSAGE FREQUENCY* | DIRECTIONS | |
Acetaminophen 500 mg (in each gelcap) | 2 gelcaps every 6 hours while symptoms last | Not to exceed 6 gelcaps in 24 hours, unless directed by a doctor Total labeled daily dose: | |
*For children under 12 years, at healthcare professional’s discretion.
†The efficacy and safety of TYLENOL® at 4000 mg/day are well established.
Extended Release TYLENOL® 8HR Arthritis Pain Tablets | |||
---|---|---|---|
ACTIVE INGREDIENT ACTIVE INGREDIENT, DOSAGE* & DIRECTIONS | DOSAGE FREQUENCY* | DIRECTIONS | |
Acetaminophen 650 mg (in each bi-layer tablet) | 2 bi-layer tablets every 8 hours with water | Not to exceed 6 bi-layer tablets in 24 hours Total labeled daily dose: | |
*For children under 18 years of age, at healthcare professional’s discretion.
Extended Release TYLENOL® 8HR Muscle Aches & Pain Tablets | |||
---|---|---|---|
ACTIVE INGREDIENT ACTIVE INGREDIENT, DOSAGE* & DIRECTIONS | DOSAGE FREQUENCY* | DIRECTIONS | |
Acetaminophen 650 mg (in each bi-layer tablet) | 2 bi-layer tablets every 8 hours with water | Not to exceed 6 bi-layer tablets in 24 hours Total labeled daily dose: | |
*Do not use in children under 12 years of age.
PM Extra Strength TYLENOL® PM Extra Strength Caplets | |||
---|---|---|---|
ACTIVE INGREDIENTS ACTIVE INGREDIENTS, DOSAGE* & DIRECTIONS | DOSAGE FREQUENCY* | DIRECTIONS | |
Acetaminophen 500 mg (in each caplet) | 2 caplets at bedtime | Not to exceed 2 caplets in 24 hours Total labeled daily dose: | |
*Do not use in children under 12 years of age.
This is not a complete list.
Dosage Chart: Acetaminophen (Tylenol)
Dosage Chart: Acetaminophen (Tylenol)
- New to the Area?
- Well Care / Annual Check-Ups
- “Get Acquainted” Visits
- Lab Work
- Recommended Health Maintenance Schedule
- Dosage Chart: Acetaminophen (Tylenol)
- Dosage Chart: Ibuprofen (Motrin/Advil)
- Vaccination Policy
Ped*I*Care
Should my child be seen during Ped*I*Care Hours?
Acetaminophen may be less upsetting to the stomach than ibuprofen. Therefore, in general, use of acetaminophen is preferable to ibuprofen if the patient has stomach upset or is not drinking well.
In case of doubt: First, read the package label. If uncertainty still exists, call the office.
Age | 0-3 mos | 4-11 mos | 12-23 mos | 2-3 yrs | 4-5 yrs | 6-8 yrs | 9-10 yrs | 11-12 yrs | 12+ yrs | |
---|---|---|---|---|---|---|---|---|---|---|
Weight in pounds | 6-11 | 12-17 | 18-23 | 24-35 | 36-47 | 48-59 | 60-71 | 72-95 | 96+ | |
Concentration | ||||||||||
5 ml = 160 mg | Children’s Tylenol Suspension mL | 1. 25 | 2.5 | 3.75 | 5 | 7.5 | 10 | 12.5 | 15 | 20 |
1 tab = 80 mg | Children’s Tylenol Melt-aways # of tabs | – | – | 1 ½ | 2 | 3 | 4 | 5 | 6 | 8 |
1 tab = 160 mg | Junior Tylenol Melt-aways # of tabs | – | – | – | 1 | 1 ½ | 2 | 2 ½ | 3 | 4 |
1 tab = 325 mg | Tylenol (regular adult) # tabs | – | – | – | – | ½ | 1 | 1 | 1 ½ | 2 |
1 tab = 500 mg | Tylenol (extra strength adult) # tabs | – | – | – | – | ½ | ½ | 1 | 1 | 1 ½ |
1 tab = 650 mg | Tylenol (extended release adult) # tabs | – | – | – | – | – | – | – | – | 1 |
- Check dosage form and concentration carefully!
- When choosing dose, weight is more important than age.
- Acetaminophen doses may be repeated every four hours. 5 doses in 24 hours is a reasonable maximum.
- 1 tsp (teaspoon) = 5.0 ml
Tylenol™ – instructions for use, doses, side effects, reviews of the drug:
0.056 ‰
Analogs
All forms of release, dosages, registration certificates, drug manufacturers, drug characteristics
Product Description Tylenol™ Caplets (caplets), 500 mg) based on the label, approved by the manufacturer in 2000
Approval date: 07/31/2000
Content
- Active substance
- ATX
- Pharmacological group
- Nosological classification (ICD-10)
- Composition and form of release
- pharmachologic effect
- pharmachologic effect
- Indications
- Contraindications
- Use during pregnancy and lactation
- Dosage and administration
- Side effects
- Precautionary measures
- Storage conditions
- Best before date
- Reviews
Active ingredient
Paracetamol* (Paracetamol*)
ATX
N02BE01 Paracetamol
Pharmacological group
Anilides
Nosological classification (ICD-10)
ICD-10 code list
Composition and formulation
1 caplet contains paracetamol 500 mg; in a blister 10 pcs. , in a box 1 blister or in strips of 2 pcs., in a box 50 strips.
Pharmacological action
Pharmacological action –
analgesic , antipyretic .
Inhibits cyclooxygenase, inhibits the synthesis of PG in the central nervous system and their stimulating effect on the thermoregulatory center of the hypothalamus; increases heat transfer.
Inhibits cyclooxygenase, inhibits the synthesis of PG in the central nervous system and their stimulating effect on the thermoregulatory center of the hypothalamus; increases heat transfer.
Indications
Pain of mild to moderate intensity (including headache, toothache, sore throat and general malaise), fever.
Contraindications
Hypersensitivity, severe impairment of liver and kidney function, deficiency of glucose−6-phosphate dehydrogenase, children’s age (up to 12 years).
Use during pregnancy and lactation
Acceptable, but only on medical prescription.
Dosage and Administration
Information for healthcare professionals only.
Are you a healthcare professional?
Inside, 2 caplets 3-4 times a day, but not more than 8 caplets per day.
Side effects
In rare cases, nausea, abdominal pain, allergic reactions (skin rash, itching, urticaria).
Precautions
Do not use more than 10 days for pain and 3 days as an antipyretic. It should not be taken together with other drugs containing paracetamol.
Storage conditions
At a temperature of 15–30 °C.
Keep out of reach of children.
Expiry date
4 years.
Do not use after the expiry date which is stated on the pack.
Update date: 11/21/2018
Reviews
Read all reviews and leave your own.
Information for healthcare professionals only.
Are you a healthcare professional?
TYLENOL: instructions, reviews, analogues, price in pharmacies
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- Indications for use
- Side effects
- Contraindications
- Pregnancy
- Storage conditions
- Release form
- Ingredients
9 0023 Overdose
Tylenol used for colds. Tylenol belongs to the group of non-narcotic analgesics. The drug affects the centers of thermoregulation, pain, its active ingredient is paracetamol. Tylenol does not adversely affect the mucous membranes of the gastrointestinal tract, water-salt metabolism. It affects the centers of thermoregulation and pain, thereby reducing body temperature and removing pain. This medicine does not cause retention of sodium and water ions in the body. In addition, it is completely harmless to the digestive tract, the walls of which are usually affected by other similar drugs.
Indications for use
The drug Tylenol is effective in fever associated with infections, helps with toothache, headache, as well as pain caused by arthralgia, migraine, myalgia that occurs with algomenorrhea.
Directions for use
By mouth Tylenol is taken one to two hours after a meal. Children from 12 years old, weighing more than 40 kg and adults are prescribed Tylenol in a single dosage of 500 mg. Take Tylenol about 4 times a day. Therapy lasts 5-7 days. If the patient suffers from a violation of the liver, kidneys or Gilbert’s syndrome, he needs to adjust the dose down. The same applies to older patients. In addition to reducing the dose of Tylenol for such patients, it is practiced to increase the intervals between doses. Children up to six months, weighing up to 7 kg are prescribed 350 mg of Tylenol; children under 1 year old, weighing up to 10 kg are given 500 mg of Tylenol; children under three years old, weighing up to 15 kg give 750 mg; up to 6 liters, weighing up to 22 kg – 1 g; children 9l. , weighing up to 30 kg give 1.5 g of Tylenol; children up to 12 liters – 2 g. Suspension for children 6-12 liters. give 10-20 ml; children 1-6 years old. – 5-10 ml; children from three months to one year are given 2.5-5 ml. For children under 3 months, the dosage of Tylenol is determined individually. Give children a suspension 4 times a day. Without medical supervision, the drug can be given only for 3 days to relieve fever and no more than 5 days for pain relief. Tylenol rectal suppositories are prescribed for adults at a dosage of 500 mg, they are used no more than four times a day. Children 12-15 years old. prescribe 250-300 mg of Tylenol about four times a day; 8-12 years – 250-300 mg no more than three times a day; 6-8 years old – 750-900 mg in three doses; 4-6 years – 150 mg about 3-4 times a day; child 2-4 years old – 300-450 mg in two or three doses; 1-2 years – 80 mg of Tylenol no more than four times a day; from six months to a year – 80 mg no more than three times a day; 3-6 months
– 160 mg per day, in two divided doses.
Side effects
Tylenol side effects may cause skin rash, erythema, angioedema, dizziness, nausea, epigastric pain, agitation, hepatonecrosis, anemia, dyspnea, cyanosis, heart pain, agranulocytosis, thrombocytopenia denia, leukopenia , neutropenia. In large quantities, Tylenol can be nephrotoxic, resulting in renal colic, papillary necrosis, or interstitial nephritis.
Contraindications
:
Tylenol is contraindicated in case of allergy to it, children under one month old. Caution is observed when prescribing Tylenol to patients with renal, hepatic insufficiency, benign hyperbilirubinemia, viral hepatitis, suffering from alcoholism, diabetes, lack of glucose-6-phosphate dehydrogenase, as well as elderly patients, lactating, pregnant women, children under 3 months.
Pregnancy
:
Tylenol should not be taken during pregnancy unless the physician believes that the benefit to the mother at that time is more important than the potential harm to the fetus.
Interaction with other drugs:
Tylenol reduces the effectiveness of uricosuric drugs. The concomitant use of paracetamol in high doses increases the effect of anticoagulant drugs (decrease in the synthesis of procoagulant factors in the liver). Inducers of microsomal oxidation in the liver (phenytoin, ethanol, barbiturates, rifampicin, phenylbutazone, tricyclic antidepressants), ethanol and hepatotoxic drugs increase the production of hydroxylated active metabolites, which makes it possible to develop severe intoxications even with a small overdose. Prolonged use of barbiturates reduces the effectiveness of paracetamol. Ethanol contributes to the development of acute pancreatitis. Microsomal oxidation inhibitors (including cimetidine) reduce the risk of hepatotoxicity. Long-term combined use of paracetamol and other NSAIDs increases the risk of developing “analgesic” nephropathy and renal papillary necrosis, the onset of end-stage renal failure. Simultaneous long-term administration of paracetamol in high doses and salicylates increases the risk of developing kidney or bladder cancer. Diflunisal increases the plasma concentration of paracetamol by 50% – the risk of developing hepatotoxicity. Myelotoxic drugs increase the manifestations of hematotoxicity of the drug.
Overdose
:
Overdose symptoms of Tylenol : in the first 24 hours – pallor, nausea, vomiting and abdominal pain; after 12-48 hours – damage to the kidneys and liver with the development of liver failure (encephalopathy, coma, death), cardiac arrhythmias and pancreatitis. Liver damage is possible when taking 10 g or more (in adults).
Treatment: administration of methionine orally or intravenously with N-acetylcysteine.
Storage conditions
Tylenol Store at 15-30°C.
Formulation
Capsules, effervescent powder for oral solution [children], solution for infusion, oral solution [children], syrup, rectal suppositories, rectal suppositories [children], oral suspension , suspension.