Can you get high on cyclobenzaprine. Cyclobenzaprine High: Risks, Side Effects, and Addiction Potential of Flexeril Abuse
Can cyclobenzaprine (Flexeril) cause a high. What are the dangers of abusing this muscle relaxant. How does it interact with other substances. What are the signs of cyclobenzaprine addiction and overdose. Where to find treatment for prescription drug abuse.
Understanding Cyclobenzaprine (Flexeril): Uses and Mechanism of Action
Cyclobenzaprine, commonly known by its brand name Flexeril, is a prescription muscle relaxant used to treat muscle-related pain, spasms, and injuries. Despite being classified as a low-risk substance by the DEA, cyclobenzaprine abuse has become increasingly common.
How does cyclobenzaprine work in the body? The medication functions by blocking pain signals sent from nerves to the brain, rather than directly affecting the muscles. This interaction with the central nervous system (CNS) can lead to wide-ranging side effects impacting respiratory, cardiovascular, and gastrointestinal functions.
Key Points About Cyclobenzaprine:
- Onset of effects: 20-40 minutes after ingestion
- Duration: 4-6 hours for immediate-release tablets, up to 24 hours for extended-release
- Intended use: Short-term treatment, typically a few weeks at a time
- Risk factors: Long half-life, potential for habit formation and toxic buildup
The Cyclobenzaprine High: Effects and Dangers
While cyclobenzaprine is considered relatively safe when used as prescribed, misuse can lead to a “high” characterized by sedation and mild euphoria. This recreational use poses significant risks, especially when combined with other substances.
Is it possible to get high on cyclobenzaprine alone? Yes, but the effects are generally mild compared to other drugs of abuse. However, the danger increases substantially when cyclobenzaprine is mixed with other substances, particularly CNS depressants like alcohol, benzodiazepines, or barbiturates.
Potential Consequences of Cyclobenzaprine Abuse:
- Increased risk of overdose
- Development of addiction
- Withdrawal symptoms upon cessation
- Rare but life-threatening complications
Drug Interactions and Heightened Risks
The dangers of cyclobenzaprine abuse escalate dramatically when combined with other substances. These interactions can lead to intensified side effects, increased risk of overdose, and potentially life-threatening conditions.
Dangerous Combinations:
- CNS Depressants: Amplifies sedative effects, increases risk of respiratory depression
- Stimulants: Can lead to unpredictable and dangerous cardiovascular effects
- Antidepressants: Risk of serotonin syndrome, a potentially fatal condition
- Over-the-counter medications: Even common drugs like migraine medication can interact negatively
What is serotonin syndrome? It’s a condition caused by excessive serotonin levels in the body, which can occur when cyclobenzaprine is combined with certain other medications. Symptoms can range from mild to severe and may develop within hours of taking the interacting drugs.
Recognizing the Side Effects of Cyclobenzaprine Abuse
Cyclobenzaprine abuse can lead to a wide range of side effects, varying from common and relatively mild to rare and potentially life-threatening. Understanding these effects is crucial for identifying problematic use and seeking timely intervention.
Common Side Effects:
- Constipation
- Dizziness
- Drowsiness
- Dry mouth
- Extreme fatigue
- Heartburn
- Headache
- Increased heart rate
- Nausea
Uncommon Side Effects:
- Chest pain
- Difficulty breathing
- Fast or irregular heartbeat
- Hives or skin rash
- Swelling of tongue or face
Serious Side Effects:
- Agitation
- Diarrhea
- Fast heartbeat
- Fever
- Hallucinations
- Loss of coordination
- Muscle stiffness
- Slurred speech
- Shivering
- Sweating
- Twitching
- Vomiting
When should you seek medical attention for cyclobenzaprine side effects? If you experience any of the serious side effects listed above, or if common side effects persist or worsen, it’s crucial to consult a healthcare professional immediately.
Cyclobenzaprine Overdose: Symptoms and Emergency Response
While cyclobenzaprine overdose is relatively rare when the medication is used as prescribed, the risk increases significantly with recreational use or when combined with other substances. Recognizing the signs of an overdose can be life-saving.
Symptoms of Cyclobenzaprine Overdose:
- Severe drowsiness or difficulty staying awake
- Confusion or disorientation
- Hallucinations
- Rapid heartbeat or palpitations
- High blood pressure
- Dilated pupils
- Muscle rigidity
- Nausea and vomiting
- Seizures
- Difficulty breathing or shallow breathing
What should you do if you suspect a cyclobenzaprine overdose? Immediately call emergency services or your local poison control center. Do not try to induce vomiting unless specifically instructed to do so by a medical professional. If the person is unconscious, turn them on their side to prevent choking if vomiting occurs.
Cyclobenzaprine Addiction: Signs, Symptoms, and Treatment Options
While cyclobenzaprine is not classified as a controlled substance, it still carries a risk of addiction, especially when misused. Recognizing the signs of addiction is crucial for early intervention and successful treatment.
Signs of Cyclobenzaprine Addiction:
- Taking higher doses than prescribed or using without a prescription
- Using the drug for longer periods than intended
- Unsuccessful attempts to cut down or stop use
- Spending a significant amount of time obtaining, using, or recovering from the drug
- Neglecting work, school, or family responsibilities due to drug use
- Continuing use despite negative consequences
- Experiencing withdrawal symptoms when not using the drug
How is cyclobenzaprine addiction treated? Treatment typically involves a combination of medical detoxification, behavioral therapy, and support groups. In some cases, medication-assisted treatment may be used to manage withdrawal symptoms and cravings.
Treatment Options for Cyclobenzaprine Addiction:
- Medical Detoxification: Supervised withdrawal management to ensure safety and comfort
- Inpatient Rehabilitation: Intensive, residential treatment programs
- Outpatient Programs: Flexible treatment options for those who cannot commit to full-time residential care
- Cognitive Behavioral Therapy (CBT): Helps identify and change drug-related behaviors and thought patterns
- Support Groups: Peer support through organizations like Narcotics Anonymous
- Aftercare Planning: Ongoing support to maintain recovery and prevent relapse
Preventing Cyclobenzaprine Abuse: Safe Use and Alternatives
Preventing cyclobenzaprine abuse starts with understanding the risks and using the medication responsibly. For those prescribed cyclobenzaprine, following medical advice and exploring alternative pain management strategies can help reduce the risk of misuse.
Tips for Safe Cyclobenzaprine Use:
- Take the medication exactly as prescribed
- Do not increase dosage without consulting your doctor
- Avoid alcohol and other CNS depressants while using cyclobenzaprine
- Store the medication securely and out of reach of others
- Dispose of unused medication properly
- Inform your healthcare provider of all other medications you’re taking
What are some alternatives to cyclobenzaprine for muscle pain relief? Depending on the underlying cause of pain, alternatives may include non-steroidal anti-inflammatory drugs (NSAIDs), physical therapy, acupuncture, or other non-pharmacological interventions. Always consult with a healthcare professional before changing your treatment plan.
Non-Pharmacological Alternatives for Muscle Pain:
- Physical Therapy: Targeted exercises and stretches to improve muscle function and reduce pain
- Massage Therapy: Can help relax tense muscles and improve circulation
- Heat and Cold Therapy: Alternating heat and cold can reduce inflammation and promote healing
- Yoga and Stretching: Gentle movements can improve flexibility and reduce muscle tension
- Mindfulness and Relaxation Techniques: Can help manage pain perception and reduce muscle tension
Cyclobenzaprine, while effective for short-term muscle pain relief, carries risks when misused or combined with other substances. Understanding these risks, recognizing the signs of abuse and addiction, and knowing when to seek help are crucial for safe use and overall health. If you or someone you know is struggling with cyclobenzaprine misuse, don’t hesitate to reach out to healthcare professionals or addiction specialists for support and guidance. Remember, early intervention can make a significant difference in preventing the escalation of substance abuse and its potentially life-threatening consequences.
What Does A Cyclobenzaprine High Feel Like? Is It Dangerous?
Cyclobenzaprine, better known as the brand name medication Flexeril, is a muscle relaxant used to treat muscle-related pain such as tenderness and spasms from strains and other types of muscle injuries. Despite being deemed low to no-risk by the DEA (Flexeril is not a controlled substance) cyclobenzaprine abuse is a fairly regular occurrence that is at its most dangerous when it’s combined with other substances be they legal or illicit, depressant or stimulant.
How Does Cyclobenzaprine Work?
Cyclobenzaprine works by blocking the pain signals sent from nerves to the brain (two key components of the central nervous system), rather than impacting the muscles directly. Like any other drug that impacts the CNS, side effects are far-reaching and affect respiratory, cardiovascular, and even gastrointestinal function. Side effects can take place within 20 to 40 minutes of ingestion and last 4-6 hours for immediate-release tablets or up to 24 hours for extended-release tablets.
Pain medication of any kind has a high potential to be habit-forming, but those with long half-lives such as cyclobenzaprine face a significant risk of doing so and causing toxic levels of medication build-up. As a result, this medication is only intended for short-term use or periods for a few weeks at a time.
Can Cyclobenzaprine Get You High?
On its own, cyclobenzaprine has minimal risks or long-term effects. However, it does have sedative properties, and misusing this drug (taking too much, crushing or chewing a capsule rather than swallowing, using it without a prescription) can result in a cyclobenzaprine high.
A cyclobenzaprine high causes feelings of sedation and mild euphoria. Those effects—and its dangers—are heightened when cyclobenzaprine is combined with other drugs, particularly central nervous system depressants such as alcohol, benzos, and barbiturates.
Wherever there are drug highs to be found, there are adverse effects including the risk of overdosing, developing an addiction, and even withdrawal effects. In rare circumstances, cyclobenzaprine can even cause life-threatening complications.
Risks & Drug Interactions
The risk of adverse side effects becomes more serious in instances when cyclobenzaprine was combined with other drugs. When mixed with depressants, it can amplify the effects of those drugs to cause intense and debilitating consequences that affect cognition, consciousness, and basic bodily functions. It also significantly increases the likelihood of a cyclobenzaprine overdose which can result in extreme drowsiness and CNS depression.
However, cyclobenzaprine can also be harmful when combined with stimulants, antidepressants, or even simple over-the-counter migraine medication. The presence of cyclobenzaprine in the body can cause a condition called serotonin syndrome; when there’s too much serotonin being present in the body. These symptoms can take effect within hours of taking a medication, ranging from mild to severe, and yes, can even result in death.
Side Effects of Cyclobenzaprine Abuse
Common Side Effects
- Constipation
- Dizziness
- Drowsiness
- Dry mouth
- Extreme fatigue
- Heartburn
- Headache
- Increased heart rate
- Nausea
Uncommon Side Effects
- Chest pain
- Difficulty breathing
- Fast or irregular heartbeat
- Hives or skin rash
- Swelling of tongue or face
Serious Side Effects
- Agitation
- Diarrhea
- Fast heartbeat
- Fever
- Hallucinations
- Loss of coordination
- Muscle stiffness
- Slurred speech
- Shivering
- Sweating
- Twitching
- Vomiting
Struggling With Prescription Painkillers?
If you are struggling with prescription painkillers, you’re not alone. These drugs (including opioid analgesics) are the leading cause of addiction and overdose in the nation. Specialized addiction treatment centers can help individuals get through unpleasant withdrawal side effects and safely overcome any compulsive or inappropriate use of pain meds. Call today to learn more.
Sources:
https://www.drugs.com/tips/cyclobenzaprine-patient-tips
https://medlineplus.gov/druginfo/meds/a682514.html
Treatment for Recreational Use of Flexeril
A prescription-based medication, cyclobenzaprine (known by the brand names Flexeril and Amrix) is similar to tricyclic antidepressants and being both diverted and abused, Drug Enforcement Administration (DEA) reports.
Designed for the short-term relief of limited motion and pain that may be caused by muscle spasms, cyclobenzaprine is a central nervous system muscle relaxer that may stop hyperactive nerve firings that can cause muscles to spasm.
The DEA reports that there were more than 25 million prescriptions written for cyclobenzaprine in 2011, which may be a common medication prescribed for back pain. Flexeril comes in tablet form in both immediate- and extended-release formations to be swallowed.
Who Abuses Flexeril and Why?
NIDA reports that young adults between the ages of 18 and 25 (according to 2014 data) abuse prescription drugs at the highest rates of any other age demographic. Young adults may use the Internet to access information on how to abuse Flexeril and the possible desirable effects that may come from the drug’s recreational use. Flexeril may be used to heighten the effects of alcohol or other drugs when used recreationally.
Prescription drugs are abused across almost all age, gender, race, cultural, and socioeconomic demographics, however. For example, the Substance Abuse and Mental Health Services Administration (SAMHSA) reports that prescription drug abuse is increasing for older adults in their 50s, which may be of particular concern due to the range of negative side effects that specifically impact this population group. Flexeril in particular is not even generally prescribed to the elderly population, according to the FDA, because of the high risk factors.
Additionally, individuals with a legitimate prescription to Flexeril may develop a tolerance to the drug, requiring them to take higher and more frequent doses to feel its effects. Drug dependence can develop wherein the brain becomes accustomed to the interaction of cyclobenzaprine and begins to rely on it in order to keep functioning the same way.
Dependence on cyclobenzaprine is recognized by the onset of withdrawal symptoms when the drug leaves the bloodstream. These may include fatigue, nausea, headache, and general malaise.
Understanding Drug Dependence and Addiction
The terms drug dependence and addiction are often used interchangeably; however, they are not the same thing. A dependence on a drug can occur independently of addiction. It is a physical reaction to the brain needing a particular drug to remain balanced. Drug dependence can form even when a drug is taken for medical reasons and used exactly as prescribed. Narcotic drugs, like opioids, and sedatives, like benzodiazepines and tricyclic antidepressants (which are similar in structure to cyclobenzaprine), can cause physical dependence.
Medical help is needed to stop taking a drug after a person has become dependent on it, as withdrawal symptoms and drug cravings may be significant. Instead of stopping the drug suddenly, these drugs can be tapered off slowly, or their dosage slowly reduced over a period of time to minimize withdrawal. This should only be done under medical supervision. Significant dependence, often created by the nonmedical use of drugs, is best treated with medical detox where medications may be used and medical supervision is available around the clock.
Addiction is not just physical but also behavioral. Addiction is classified as a disease by the American Society of Addiction Medicine (ASAM) that is related to changes in brain structure and chemical makeup as the result of substance abuse. The main indicator of drug addiction is a loss of control over drug use. An individual battling addiction may make multiple attempts to stop using the drug, may take more than intended at one time, or may take the drug for longer than initially desired. Individuals suffering from addiction may use drugs in situations that could potentially be hazardous and continue abusing them even when negative consequences are clear.
Signs of a Cyclobenzaprine Overdose
A drug overdose occurs when a toxin is unable to be successfully metabolized and removed from the body, and certain bodily functions are negatively affected. In the case of cyclobenzaprine, the Journal of Occupational Medicine and Toxicology reports that more than 100 mg of the drug taken in one dose can cause a toxic overdose.
The FDA publishes the following as potential overdose signs of Flexural:
- Drowsiness
- Rapid heart rate (tachycardia)
- High blood pressure (hypertension)
- Tremors
- Slurred speech
- Agitation
- Confusion
- Dizziness
- Nausea
- Vomiting
- Hallucinations
- Loss of muscle control (ataxia)
- Coma
Less common and more serious symptoms of a Flexeril overdose, according to the drug’s prescription information published by the FDA, include:
- Chest pain
- Seizures
- Extremely low blood pressure (hypotension)
- The heart stops beating (cardiac arrest)
- Irregular heart rate (cardiac dysrhythmia)
- Fever, muscle rigidity, and altered mental state (neuroleptic malignant syndrome)
A toxic overdose necessitates immediate medical attention.
The DEA reported that in 2010, there were over 10,000 mentions of cyclobenzaprine in calls to the American Association of Poison Control Centers. The Drug Abuse Warning Network (DAWN) published that in 2011, more than 11,000 people sought emergency department (ED) treatment for abuse of cyclobenzaprine.
Recovery Is Possible
If an overdose on cyclobenzaprine is suspected, call 911. Immediate medical attention is always needed in cases of overdose.
If you, or someone you love, have been struggling with Flexeril abuse, treatment is needed. With medical detox and comprehensive addiction treatment, you can leave such abuse in your past and embrace a happier, healthier future without substance abuse of any kind.
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antidepressants
Last Updated on Nov 16, 2022
Rec. INN drug interaction Included in preparations: Pharmacological actionCyclobenzaprine is a centrally acting muscle relaxant. Indications of the active substance |
M40-M54 | Dorsopathies (M40-M54) |
M54 | Dorsalgia |
M54.2 | Cervicalgia |
M54.3 | Sciatica |
M54. 4 | Lumbago with sciatica |
M54.6 | Pain in the thoracic spine |
R25.2 | Convulsions and spasm |
Dosing regimen
Int. The recommended dose for adults is 15 mg/day. If necessary, the dose can be increased to 22.5-30 mg / day.
Elderly patients, patients with mild hepatic impairment require dose adjustment. The use of cyclobenzaprine in patients with moderate to severe hepatic impairment is not recommended.
Side effects
Mental disorders: very often – drowsiness; often – irritability, anxiety; infrequently – psychosis, agitation, abnormal thoughts and dreams, hallucinations, disorientation, depression, insomnia.
From the side of the central nervous system: often – headache, dizziness, fatigue; infrequently – fainting, convulsions, ataxia, dysarthria, tremor, convulsions, muscle hypertonicity, serotonin syndrome, paresthesia, tinnitus, diplopia, taste disturbances.
From the immune system: infrequently – severe allergic reactions (anaphylactic reactions, angioedema), swelling of the face, swelling of the tongue, itching, rash, urticaria.
From the urinary system: infrequently – increased frequency of urination, urinary retention.
From the respiratory system: often – pharyngitis, infections of the upper respiratory tract.
From the digestive system: very often – dry mouth; often – abdominal pain, gastroesophageal reflux, constipation, diarrhea, nausea; infrequently – vomiting, anorexia, gastritis, thirst, bloating, jaundice, hepatitis, cholestasis, increased ALT activity.
From the side of the cardiovascular system: infrequently – tachycardia, arrhythmia, palpitations, hypotension, vasodilation.
On the part of the body as a whole: infrequently – increased sweating, weakness in certain muscle groups, malaise.
Contraindications for use
Hypersensitivity to cyclobenzaprine; the simultaneous use of drugs from the group of MAO inhibitors or the end of the course of treatment with MAO inhibitors less than 14 days before the start of therapy with cyclobenzaprine; recovery period after acute myocardial infarction; cardiac arrhythmia and conduction disorders, including blockade of the conduction system of the heart; congestive heart failure; hyperthyroidism; age up to 18 years.
Pregnancy and lactation
Contraindicated during pregnancy and during breastfeeding.
Use in hepatic impairment
Patients with mild hepatic impairment require dose adjustment. The use of cyclobenzaprine in patients with moderate to severe hepatic impairment is not recommended
Use in children
Use is contraindicated in children and adolescents under 18 years of age.
Elderly use
Cyclobenzaprine should be used in elderly patients only if absolutely necessary, dose adjustment is required.
Precautions
Cyclobenzaprine should only be used for a short period (up to 2-3 weeks) as there is insufficient evidence of efficacy over a longer period of time. The use of the drug cyclobenzaprine has not been shown to be effective in the treatment of muscle spasm associated with diseases of the brain or spinal cord, or with cerebral palsy.
In the elderly, the concentration of cyclobenzaprine in blood plasma increases. Also, in elderly patients, the risk of adverse reactions from the central nervous system and from the cardiovascular system, as well as the risk of developing drug interactions and the effect of the drug on concomitant diseases, may be increased. In this regard, cyclobenzaprine should be used in elderly patients only if clearly needed.
The concentration of cyclobenzaprine in patients with impaired liver function is increased. Cyclobenzaprine should be used with caution in patients with mild hepatic impairment. The use of cyclobenzaprine in patients with moderate to severe hepatic impairment is not recommended due to insufficient data on the use.
Sudden discontinuation of the drug after prolonged use may in rare cases cause nausea, headache and malaise. These symptoms do not indicate the development of addiction.
Influence on the ability to drive vehicles and mechanisms
increased concentration of attention and speed of psychomotor reactions.
Drug interactions
The development of a potentially life-threatening condition – serotonin syndrome has been reported with the use of cyclobenzaprine in combination with the following drugs: selective serotonin reuptake inhibitors, selective serotonin and norepinephrine reuptake inhibitors, tricyclic antidepressants, tramadol, buprop ion, meperidine , verapamil or MAO inhibitors. If the development of symptoms of serotonin syndrome is noted, it is necessary to immediately stop taking cyclobenzaprine and any concomitant serotonergic agents and start symptomatic treatment.
If concomitant treatment with cyclobenzaprine and other serotonergic drugs is clinically warranted, careful monitoring of the patient is recommended, especially at the start of treatment or when the dose is increased.
Cyclobenzaprine is structurally similar to tricyclic antidepressants. Against the background of the use of tricyclic antidepressants, cases of arrhythmia, sinus tachycardia, intracardiac conduction disturbances, which can cause the development of myocardial infarction and stroke, have been reported.
Some of the more serious CNS reactions associated with tricyclic antidepressants have been observed in short-term studies with cyclobenzaprine for indications other than skeletal muscle spasm for musculoskeletal disorders, mostly at higher than recommended doses.