Can biotin supplements be taken during breastfeeding. How does pregnancy affect biotin metabolism. What are the potential risks of biotin supplementation for nursing mothers. Are there effective alternatives for postpartum hair health.

Understanding Biotin and Its Role in Pregnancy and Lactation

Biotin, also known as vitamin B7, plays a crucial role in various bodily functions, including metabolism and hair health. During pregnancy and lactation, women’s bodies undergo significant changes that can affect biotin metabolism. Recent studies have shown that pregnancy and breastfeeding may alter biomarkers of biotin metabolism in women, even when consuming a controlled diet.

Why does this matter for new mothers? Postpartum hair loss is a common concern, and many turn to biotin supplements in hopes of maintaining their pregnancy-induced luscious locks. However, the relationship between biotin supplementation and breastfeeding is more complex than it may seem at first glance.

The Safety of Biotin Supplementation During Breastfeeding

Is it safe to take biotin while breastfeeding? Theoretically, yes, but the answer isn’t as straightforward as one might hope. Dr. Muneeb Shah, a dermatologist with a significant social media following, explains, “Biotin itself is safe in pregnancy. However, supplements are often unregulated and taking unnecessary supplements that could be contaminated is really not a good idea.”

The key takeaway here is that while biotin is not inherently harmful, the lack of regulation in the supplement industry poses potential risks. Additionally, Dr. Shah points out that “Biotin has not been proven to promote hair growth in anyone unless you are truly biotin deficient, which is very unlikely!”

Recommended Dosage for Breastfeeding Women

For those considering biotin supplementation, it’s crucial to be aware of the recommended dosage. Krystal Nicole Duhaney, a registered nurse and lactation consultant, advises that “the recommended dietary allowance of biotin for breastfeeding women is 35 micrograms.” This relatively low dosage highlights the importance of consulting with a healthcare provider before starting any new supplement regimen.

Potential Side Effects and Risks of Biotin Supplementation

While biotin is generally considered safe, there are potential side effects and risks associated with its use, especially during breastfeeding. Dr. Shah warns of a recent FDA caution regarding biotin supplementation: “Biotin has been shown to interfere with lab tests, including thyroid labs, pregnancy tests, and laboratory markers of cardiac damage.”

This interference with lab results can have serious implications. For instance, it could potentially lead to missed diagnoses of heart attacks due to falsely low cardiac damage markers. Given the frequency of lab tests during pregnancy and postpartum, it’s crucial to disclose any biotin supplementation to healthcare providers.

Common Side Effects

• Nausea and upset stomach
• Increased breakouts
• Potential changes in breast milk taste

Dr. Alexis Parcells notes that the most common complaints when taking biotin are nausea and an upset stomach. Some individuals have also reported increased acne breakouts. Interestingly, Duhaney mentions that biotin supplementation might alter the taste of breast milk, which in rare cases could lead to a baby rejecting it.

The Efficacy of Biotin for Hair Growth in Healthy Individuals

Despite its popularity as a hair growth supplement, the efficacy of biotin for this purpose in healthy individuals is questionable. Dr. Taraneh Shirazian, an OB/GYN and founder of Mommy Matters, states, “There is little evidence that biotin helps hair growth in healthy individuals. Biotin is not very effective as a supplement.”

This lack of evidence for biotin’s effectiveness in promoting hair growth in non-deficient individuals raises questions about its widespread use. Why, then, is biotin often included in prenatal and postnatal vitamins?

Biotin in Prenatal and Postnatal Vitamins

The inclusion of biotin in prenatal and postnatal vitamins is not aimed at promoting fetal hair growth. Instead, it’s based on studies suggesting that pregnant women break down biotin at a more rapid rate, potentially leading to biotin deficiency in pregnant or lactating individuals. However, true biotin deficiency is rare in well-nourished populations.

Understanding Postpartum Hair Loss

To comprehend why many new mothers seek biotin supplementation, it’s essential to understand the phenomenon of postpartum hair loss. During pregnancy, elevated estrogen levels cause hair to shed at a much slower rate, resulting in fuller, thicker hair. However, as hormones return to pre-pregnancy levels postpartum, a significant amount of hair shedding occurs.

Dr. Joshua Zeichner explains, “We know that hair thinning after delivery is common, a condition known as telogen effluvium. The hairs are shocked into a resting phase and rapidly fall out.” This sudden hair loss can be distressing for new mothers, prompting the search for solutions like biotin supplementation.

The Temporary Nature of Postpartum Hair Loss

It’s crucial for new mothers to understand that postpartum hair loss is typically a temporary condition. Dr. Zeichner reassures, “The good news is that this condition itself is limited and corrects itself within a year.” This natural resolution occurs as hormones stabilize and the hair growth cycle returns to its pre-pregnancy state.

Alternatives to Biotin for Postpartum Hair Health

Given the limited evidence supporting biotin’s efficacy for hair growth in healthy individuals, what alternatives can new mothers consider for maintaining postpartum hair health? While patience is key, there are several strategies that may help support hair health during this transitional period:

1. Balanced nutrition: Ensure a diet rich in vitamins and minerals essential for hair health, including iron, zinc, and vitamin D.
2. Stress management: High stress levels can exacerbate hair loss, so implementing stress-reduction techniques may be beneficial.
3. Gentle hair care: Avoid harsh treatments and excessive heat styling, which can further damage fragile postpartum hair.
4. Scalp care: Maintaining a healthy scalp environment can support hair growth and retention.
5. Consult a dermatologist: For persistent concerns, a dermatologist can provide personalized advice and treatments.

The Importance of Consulting Healthcare Providers

Throughout this discussion, one theme remains constant: the importance of consulting healthcare providers before starting any new supplement regimen, especially during pregnancy and breastfeeding. This is crucial for several reasons:

• Individual health needs vary, and what’s safe for one person may not be for another.
• Healthcare providers can assess for true biotin deficiency, which is rare but possible.
• They can advise on potential interactions with medications or other supplements.
• Providers can offer evidence-based alternatives for addressing postpartum hair concerns.

By working closely with healthcare providers, new mothers can ensure they’re making informed decisions about their postpartum health and hair care routines.

The Role of Diet in Biotin Intake and Hair Health

While the efficacy of biotin supplements for hair growth in healthy individuals is questionable, obtaining adequate biotin through diet remains important for overall health. Biotin is naturally present in a variety of foods, and a balanced diet can typically provide sufficient amounts for most people, including breastfeeding mothers.

Biotin-Rich Foods

Incorporating biotin-rich foods into your diet can help ensure adequate intake without the need for supplements. Some excellent sources of biotin include:

• Egg yolks
• Nuts (especially almonds and peanuts)
• Seeds (such as sunflower seeds)
• Sweet potatoes
• Spinach and other leafy greens
• Broccoli
• Salmon and other fatty fish
• Avocados
• Whole grains

By focusing on a diverse, nutrient-rich diet, breastfeeding mothers can support their overall health and potentially their hair health without relying on supplements.

Understanding the Limitations of Supplement Regulation

One of the key concerns raised by experts regarding biotin supplementation is the lack of regulation in the supplement industry. This issue extends beyond biotin and affects many dietary supplements available on the market.

In the United States, dietary supplements are regulated differently from prescription and over-the-counter drugs. The FDA does not review dietary supplement products for safety and effectiveness before they are marketed. This means that the quality and content of supplements can vary widely between brands and even between batches of the same product.

Implications for Breastfeeding Mothers

For breastfeeding mothers, this lack of stringent regulation raises several concerns:

• Potential contamination: Without strict oversight, supplements may contain contaminants not listed on the label.
• Dosage accuracy: The actual amount of biotin in a supplement may differ from what’s stated on the packaging.
• Interactions with medications: Unregulated supplements may interact with medications in unexpected ways.
• Transfer to breast milk: The effects of supplement ingredients on breast milk composition are not always well-studied.

These factors underscore the importance of caution when considering any supplement during breastfeeding and highlight why healthcare providers often recommend obtaining nutrients through diet whenever possible.

The Science Behind Biotin Metabolism During Pregnancy and Lactation

The original study mentioned in the title, “Pregnancy and Lactation Alter Biomarkers of Biotin Metabolism in Women Consuming a Controlled Diet,” provides valuable insights into how the body’s handling of biotin changes during these crucial periods. Understanding these changes can help contextualize the debate surrounding biotin supplementation for breastfeeding mothers.

Key Findings

While the full details of the study are not provided in the original text, we can infer some important points:

1. Altered biomarkers: Pregnancy and lactation appear to change how the body processes and utilizes biotin, as evidenced by alterations in biotin metabolism biomarkers.
2. Controlled diet: These changes were observed even when women were consuming a controlled diet, suggesting that the alterations are due to physiological changes rather than dietary factors alone.
3. Potential increased need: The altered metabolism might indicate an increased need for biotin during pregnancy and lactation, though this doesn’t necessarily mean that supplementation is required.

These findings highlight the complex interplay between nutritional needs and physiological changes during pregnancy and breastfeeding. They also underscore why blanket recommendations for or against biotin supplementation are challenging to make and why individualized guidance from healthcare providers is so crucial.

Balancing Postpartum Hair Concerns with Breastfeeding Safety

The desire for healthy, full hair after giving birth is understandable, but it’s essential to balance these aesthetic concerns with the safety and well-being of both mother and baby during breastfeeding. This balance requires a nuanced approach that considers multiple factors:

Prioritizing Breast Milk Quality

The primary concern for breastfeeding mothers should be maintaining the quality and safety of their breast milk. Any interventions, including supplements, should be carefully evaluated for their potential impact on breast milk composition and the nursing infant.

Understanding Natural Hair Cycles

Educating new mothers about the natural cycle of hair growth and shedding during and after pregnancy can help alleviate concerns and reduce the urge to seek potentially unnecessary interventions. Knowing that postpartum hair loss is typically temporary can provide reassurance and patience.

Focusing on Overall Health

Rather than targeting hair health in isolation, a holistic approach to postpartum wellness can yield better results. This includes:

• Adequate rest and sleep (as much as possible with a newborn)
• Stress reduction techniques
• Regular, gentle exercise as approved by healthcare providers
• A balanced, nutrient-rich diet
• Staying hydrated

By focusing on overall health, many aspects of postpartum recovery, including hair health, can be positively impacted without resorting to supplements that may pose unnecessary risks.

The Future of Postpartum Hair Care Research

As the conversation around biotin supplementation during breastfeeding highlights, there’s a clear need for more comprehensive research in the area of postpartum hair care and nutrition. Future studies could focus on several key areas:

1. Long-term effects of biotin supplementation during lactation
2. Development of safer, more targeted treatments for postpartum hair loss
3. Exploration of the relationship between overall nutrition and postpartum hair health
4. Investigation of natural, food-based interventions to support hair growth and retention after pregnancy

As research in these areas progresses, it may provide clearer guidance for new mothers and healthcare providers alike, potentially leading to more effective and safer strategies for managing postpartum hair concerns while prioritizing breastfeeding safety.

Empowering New Mothers with Knowledge

The discussion around biotin supplementation during breastfeeding underscores a broader need: empowering new mothers with accurate, evidence-based information to make informed decisions about their health and that of their babies. This empowerment can take several forms:

Education on Postpartum Changes

Comprehensive education on the physical and hormonal changes that occur postpartum can help new mothers understand and anticipate issues like hair loss, reducing anxiety and the impulse to seek quick fixes.

Critical Evaluation of Supplement Claims

Teaching new mothers how to critically evaluate supplement claims and understand the limitations of current regulations can help them make more informed choices about their health care.

Promotion of Evidence-Based Resources

Encouraging the use of reliable, evidence-based resources for information on postpartum health can help combat misinformation and reduce reliance on potentially harmful or ineffective treatments.

Fostering Open Communication with Healthcare Providers

Creating an environment where new mothers feel comfortable discussing all aspects of their health, including cosmetic concerns like hair loss, with their healthcare providers can lead to more comprehensive and personalized care.

By focusing on these areas, we can help ensure that new mothers are well-equipped to navigate the challenges of postpartum recovery, including concerns about hair health, while prioritizing the safety and well-being of themselves and their nursing infants.

Is Taking Biotin While Breastfeeding Safe? Here’s What The Experts Say

For all the discomfort of pregnancy, for many it’s also the only time that your hair looks like it could be in a shampoo commercial. Hair looks so full while you’re expecting because rising estrogen levels cause it to shed at a much slower rate. But the flipside to holding onto all this hair is that in the postpartum period, it sheds a ton and often the hair loss is around the temples and hairline so when it begins to grow back it looks like horns. Fun.

As your hormones return to their pre-pregnancy levels, postpartum hair loss is common, but that doesn’t mean you love seeing your luscious pregnancy hair stuck in the shower drain. Many of the hair care vitamins that promise longer fuller hair share an ingredient: biotin. If you’re hoping to hold onto thicker hair after giving birth, you may be wondering, is taking biotin while breastfeeding safe?

Can I Take Biotin While Breastfeeding?

Yes, theoretically you can take biotin while breastfeeding, but it may not be a good or helpful addition to your diet. “Biotin itself is safe in pregnancy. However, supplements are often unregulated and taking unnecessary supplements that could be contaminated is really not a good idea,” Dr. Muneeb Shah, MD (who, with over six million followers on TikTok, you may know as @dermdoctor) tells Romper. “Biotin has not been proven to promote hair growth in anyone unless you are truly biotin deficient, which is very unlikely!” Dr. Shah adds.

So biotin, when taken in the correct dosage, is likely safe… but it probably won’t help that much. “There are some inherited or acquired biotin deficiency where supplementation might be helpful but there is little evidence that biotin helps hair growth in healthy individuals. Biotin is not very effective as a supplement,” Dr. Taraneh Shirazian, OB/GYN and founder of Mommy Matters tells Romper. So if you suspect you have a true biotin efficiency (for example, if one of your parents does you may too), it’s a good idea to consult with your doctor.

You may notice that biotin is in your pre or post-natal vitamin, but that shouldn’t be cause for alarm as long as you clear it with your doctor. It’s not in your prenatal so your baby will have flowing hair, though. Rather, some studies show that pregnant women break down biotin at a more rapid rate, which could potentially cause a biotin deficiency in folks who are pregnant or lactating.

Are There Side Effects Of Taking Biotin While Breastfeeding?

Before you reach for the biotin supplement when you’re pregnant or nursing, consider this: “The FDA [issued] a warning recently telling people to be cautious with unnecessary biotin supplementation. Biotin has been shown to interfere with lab tests, including thyroid labs, pregnancy tests, and laboratory markers of cardiac damage,” Dr. Shah tells Romper. “The concern from the FDA was that it could lead people’s heart attacks being missed at the hospital due to troponin levels (cardiac damage markers) coming back falsely low due to interference by biotin.” Considering how many lab tests you’ll receive in pregnancy and after, you’ll want to disclose to your doctor if you’re taking biotin.

In addition to abnormal lab results, “the most common complaint when taking biotin is nausea and an upset stomach,” Dr. Alexis Parcells, M.D., tells Romper. “Others have reported increased breakouts.”

Biotin is part of the B vitamin family, which is water-soluble, meaning the body should pee out any excess (as opposed to fat-soluble vitamins A,D, E, and K, which will get stored in fat). While your body should get rid of any excess, it’s still important to note that, “the recommended dietary allowance of biotin for breastfeeding women is 35 micrograms,” Krystal Nicole Duhaney, RN, IBCLC, tells Romper. She adds that taking a biotin supplement might change the taste of your milk. In some rare cases, a drastic change in breastmilk’s taste can cause a baby to reject it.

FatCamera/E+/Getty Images

How Can I Get Fuller Hair Postpartum?

So taking biotin while breastfeeding probably isn’t your ticket to fuller hair postpartum (sorry). So what can you do? If patience when it comes to your hair isn’t your strong suit, I totally get it, and the good news is that there are products and dietary tweaks you can try.

“We know that hair thinning after delivery is common, a condition known as telogen effluvium. The hairs are shocked into a resting phase and rapidly fall out. The good news is that this condition itself is limited and corrects itself within a year,” Dr. Joshua Zeichner, MD, tells Romper. This coupled with other factors new parents know all too well (such as stress, low levels of sleep, and highly emotional events, as Dr. Parcells notes,) can also contribute to hair loss.

Zeichner recommends thickening shampoos and conditioners, specifically, Dove Breakage Remedy. “Red light therapy helps encourage delivery of oxygen and nutrients to the scalp to promote healthy follicle functioning,” he adds.

“The best advice is to limit harsh chemicals, stress on the hair (tight ponytails and frequent brushing), and keep the hair hydrated. Additionally, a balanced diet high in vitamin B and iron-rich foods can help with hair growth and strength,” Dr. Parcells tells Romper. If you’re not breastfeeding, minoxidil, a vasodilator found in products like Rogaine may help, per Dr. Shah.

However, all the doctors interviewed stressed that time is really the best remedy for thinning hair postpartum. The condition will repair itself eventually, and parenting is all about patience: with your kids and with your hair.

Experts:

Krystal Nicole Duhaney, RN, IBCLC, founder of Milky Mama

Alexis Parcells, MD, board-certified plastic surgeon, owner of Parcells Plastic Surgery and founder of SUNNIE Wrinkle Reducing Studio

Dr. Muneeb Shah, MD, dermatologist

Taraneh Shirazian, OB/GYN and founder or Mommy Matters

Joshua Zeichner, MD, dermatologist in NYC

This article was originally published on April 27, 2020

Breastfeeding While Taking High Dose Vitamins

You are here: Home / Questions / Breastfeeding While Taking High Dose Vitamins

CQ #147 – June 4, 2019

by Anne Eglash MD, IBCLC, FABM

#LACTFACT

High doses of vitamin C, B-2, B-6, B-12, K, biotin and vitamin D are unlikely to be harmful during lactation.

High Dose Vitamins

Breastfeeding Medicine 14(5) 2019

What vitamins, in high doses, are safe during breastfeeding?

High doses of some vitamins has made it into mainstream medical therapy for various health conditions. For example, high dose riboflavin 400mg (vitamin B-2) is recommended by neurologists and primary care physicians alike for migraine headache prevention (usually in combination with coenzyme Q and magnesium). But is this safe during breastfeeding?

First, let’s review the principles of how vitamins get into breastmilk. Vitamins are by definition essential nutrients that our bodies need to function, which must come from the environment usually within food. This means that the human body does not manufacture them. Breastfeeding individuals are often advised to take a multivitamin supplement, given the demand for extra vitamins required by breastmilk.

Vitamins vary in their ability to transfer into breastmilk. Fat soluble vitamins, such as vitamin D and E, easily transfer into breastmilk and reliably increase their levels. Water soluble vitamins, such as B and C are more variable in their transmission into breastmilk. If maternal ingestion of high dose vitamins leads to high levels in breastmilk, it needs to be determined whether that higher dose is safe for the nursing infant.

The author of the article for this week’s CQW reviewed the effect of maternal high dose ingestion of vitamins C, B-2, B-6, B-12, K, biotin and vitamin D on breastmilk vitamin levels. As a reference for the question below, the doses of these vitamins in prenatal vitamins are:

Which statements do you believe are accurate regarding the safety and use of high dose vitamin intake during breastfeeding? Choose 1 or more:

1. Vitamin C 500mg a day is not only safe but when combined with 100 units of vitamin E, improves the milk’s biochemical antioxidant profile.
2. Daily ingestion of 400mg of vitamin B-2 (riboflavin) should be avoided due to safety concerns for the infant.
3. A high dose of vitamin B-6, such as 200mg-600mg daily for many months/years can increase the risk of neuropathy in the mother.
4. A low maternal B-12 level can cause B-12 deficiency in the nursing infant, while maternal vitamin B-12 supplementation will prevent deficiency in the infant.
5. High dose biotin, such as 2500mcg, is likely safe during breastfeeding because it has such a wide safety margin in humans.
6. Maternal vitamin D supplement of 400-2000 units is associated with an average breastmilk level of 50-80 units per Liter. Since infants usually drink less than 1 liter of breastmilk a day, an infant would not ingest the recommended 400 units of vitamin D each day.

See the Answer

Correct Answers: A, C, D, E, F (not B)

High Dose Vitamins

Breastfeeding Medicine 14(5) 2019

Jason B Sauberan

Concentrations of most vitamins in breast milk are dependent on maternal diet. Daily vitamin supplementation to achieve adequate dietary intake is thus a recommended intervention for lactating mothers who are undernourished, or for those with dietary restrictions. Even in mothers with no known dietary deficiency risks, the use of prenatal vitamins during lactation is commonplace and is considered safe for the breastfed infant. Some lactating mothers may elect to consume high-dose or ‘‘megadose’’ vitamin therapy, beyond that required for adequate daily intake. Commonly used vitamins taken in megadoses are listed in Table 2. Depending on the vitamin, dosage, and the mother’s underlying vitamin status, this practice could potentially lead to vitamin concentrations in milk that are harmful to the infant. This column briefly reviews the available published data and provides recommendations for nursing mothers considering vitamin megadosing.

Daily dose of vitamin B-2 (riboflavin) as high as 400mg is considered safe because vitamin B-2 has a wide margin of safety. It turns the urine bright yellow, and may do the same for the infant.

High dose vitamin B-6 increases the level of B-6 in breastmilk, but its high protein binding in the maternal serum limits transmission into breastmilk. Although prolonged high doses can cause neuropathy in the mother, no negative effects have been reported in infants.

Vitamin C has been shown to be safe in high doses, such as 1000mg a day, and does not appear to significantly increase the breastmilk level, unless mom was deficient before taking the supplement.

I periodically receive phone calls from breastfeeding mothers who are taking various vitamin supplements in the form of gummies, shakes and other foods, asking if they are OK to take. Based on what we now know regarding vitamin transmission into breastmilk, if the levels of nutrients in the supplement are considered safe for the mother (according to a knowledgeable health professional) she can be advised that these are likely safe while nursing.

Biotin and breastfeeding. Can Biotin be taken while breastfeeding?

Biotin and breastfeeding. Can Biotin be taken while breastfeeding? | E-lactation

Can Biotin be taken while breastfeeding? What are the alternatives to Biotin?

April 10, 2015 (Very Low Risk)

It is an essential coenzyme for fat metabolism and other metabolic reactions and is classified among the vitamin B group.

The recommended daily dose is 10 to 200 micrograms depending on some organs and 30 to 100 micrograms. (5 at 15 micrograms for infants, 20-30 micrograms for children, 30 micrograms for pregnant women, and 35 micrograms for nursing mothers).

Biotin is found in the non-fat fraction of breast milk in an amount of 5 to 9 µg/L.

Biotin is widely distributed in most foods with very rare deficiency in people who are on an adequate diet, and no case of intoxication is known even at higher doses than recommended for daily intake.

At the date of the last update, no relevant data regarding breastfeeding was found. However, due to the lack of toxicity, a risk due to consumption at the recommended dose is unlikely.

Vitamin supplements are not required if the diet is adequate and complete.

Alternatives

We do not have alternatives for Biotin, as it is relatively safe.

Very low risk

Compatible with breastfeeding. Low risk for the baby.

Low risk

Moderately safe. Read the comment carefully.

High risk

Dangerous. Use a less risky alternative. Read the comment.

Very high risk

Very dangerous. High risk of stopping breastfeeding.

Synonyms

• Coenzyme R
• Vitamin B7 4
• Biotin
• 生物素

Names of drugs (drugs)

• Aminosam™
• Appearex™
• Bio-H-Tin™
• Deacura™
• Gabunat™

9004 3 Hard Nails™

• Hvit™
• Medebiotin™
• Medobiotin ( Medobiotin)™
• Natubiotin™
• Panabiotin™
• Rombellin™
• WOLVIT®
• DEACURA
• MEDOBIOTHIN

90 043 NATUBIOTIN

1. Hampel D, Allen LH. Analyzing B-Vitamins in Human Milk: Methodological Approaches. Crit Rev Food Sci Nutr. 2015 Abstract
2. Ares Segura S, Arena Ansótegui J, Díaz-Gómez NM; en representación del Comité de Lactancia Materna de la Asociación Española de Pediatría. La importancia de la nutrición materna durante la lactancia, ¿necesitan las madres lactantes suplementos nutricionales? [The importance of maternal nutrition during breastfeeding: Do breastfeeding mothers need nutritional supplements?] An Pediatr (Barc). 2015 Abstract Full text (link to source) Full text (link to our server)
3. Perry CA, West AA, Gayle A, Lucas LK, Yan J, Jiang X, Malysheva O, Caudill MA. Pregnancy and lactation alter biomarkers of biotin metabolism in women consuming a controlled diet. J Nutr. 2014 Abstract
4. Mock DM. Adequate intake of biotin in pregnancy: why bother? J Nutr. 2014 Abstract
5. Shibata K, Fukuwatari T, Sasaki S, Sano M, Suzuki K, Hiratsuka C, Aoki A, Nagai C. Urinary excretion levels of water-soluble vitamins in pregnant and lactating women in Japan. J Nutr Sci Vitaminol (Tokyo). 2013 Abstract Full text (link to source) Full text (link to our server)
6. University of Maryland Medical Center. Vitamin H (Biotin). Medical Reference Guide. 2013 Full text (source link) Full text (link on our server)
7. Acofarma. Biotina. Ficha tecnica. 2008 Full text (link on our server)
8. Sakurai T, Furukawa M, Asoh M, Kanno T, Kojima T, Yonekubo A. Fat-soluble and water-soluble vitamin contents of breast milk from Japanese women. J Nutr Sci Vitaminol (Tokyo). 2005 Abstract
9. Zempleni J, Mock DM. Biotin biochemistry and human requirements. J Nutr Biochem. 1999 Abstract
10. Mock DM, Mock NI, Stratton SL. Concentrations of biotin metabolites in human milk. J Pediatr. 1997 Abstract
11. D.M. Mock. Cap. 22. Biotina. EN: E.E. Ziegler, L.J. filer. Conocimientos actuales sobre nutricion. Organización Panamericana de la Salud, 7a ed. Washington, 1997
12. Mock DM, Mock NI, Dankle JA. Secretory patterns of biotin in human milk. J Nutr. 1992 Abstract
13. Mock DM, Mock NI, Langbehn SE. Biotin in human milk: methods, location, and chemical form. J Nutr. 1992 Abstract
14. [No authors listed] Dietary reference values ​​for energy and nutrients for the United Kingdom food. Report of the Panel on Dietary Reference Values ​​of the Committee on Medical Aspects of Food Policy. Rep Health Soc Subj (Lond). 1991 Abstract
15. Livaniou E, Mantagos S, Kakabakos S, Pavlou V, Evangelatos G, Ithakissios DS. Plasma biotin levels in neonates. Biol Neonate. 1991 Abstract
16. Salmenperä L, Perheentupa J, Pispa JP, Siimes MA. Biotin concentrations in maternal plasma and milk during prolonged lactation. Int J Vitam Nutr Res. 1985 Abstract
17. Dostálová L. Vitamin status during puerperium and lactation. Ann Nutr Metab. 1984 Abstract
18. Ford JE, Zechalko A, Murphy J, Brooke OG. Comparison of the B vitamin composition of milk from mothers of preterm and term babies. Arch DisChild. 1983 Abstract Full text (link to source) Full text (link to our server)
19. Roth KS. Biotin in clinical medicine–a review. Am J Clin Nutr. 1981 Abstract

instruction, composition, use in pregnancy

Home : Good to know : Drugs and medicines in pharmacies

Manual

Trade name: Biotin
ATC code: A11HA05

Show more details

Anatomical Therapeutic Chemical (ATC) is an internationally accepted drug classification system developed under the auspices of WHO. Each drug will be assigned a code of 5 levels: action on the anatomical organ (level 1), main therapeutic and pharmacological action (levels 2-4) and chemical structure (level 5)

Pharmacotherapeutic group: dietary supplement

Depending on the field of medical application, pharmacological action, as well as on the therapeutic effect, drugs are assigned a pharmacotherapeutic group.

International non-proprietary name: Biotin

The international nonproprietary name (INN) is the name of the drug recommended by the World Health Organization, or, in its absence, the common common name. It must not be used as a trade name for a medicinal product.

Composition of the medicinal product

Dosage form and packaging:

Film-coated tablets, 5 mg in blisters No. 10. In a cardboard package (3 blisters) No. 30.

Composition:

1 tablet contains the active ingredient biotin 5 mg.

Shelf life and storage conditions:

Store at room temperature in a dry place. Shelf life – 5 years.

Dispensing category: OTC

Producer: OOO PTF Farmakom (Ukraine) /

Registration:

Registration period: from 2013-05-15 to 2018-05-15

Applicant: LLC PTF “Farmakom” (Ukraine) /

Where to buy – price in pharmacies in Kiev

See prices in pharmacies ah Kiev

Method of administration and doses

Indications:

Biotin is a vitamin complex used in vitamin H hypovitaminosis. Biotin, or vitamin H, being a vital vitamin of group B, is involved in the synthesis of higher fatty acids, and also plays an important role in metabolic body processes. Participates in carbohydrate metabolism and interacts with insulin, thereby helping to maintain a stable blood sugar level; has a beneficial effect on brittleness and stratification of hair, nails, seborrheic dermatitis, growth and development disorders, controls the metabolism of fats in skin and hair cells. With baldness of non-hormonal etiology, vitamin H stops hair loss. Promotes the absorption of protein, participates in metabolic processes along with other B vitamins, as well as in the decomposition of fatty acids and in fat burning; beneficial effect on the functional state of the gastrointestinal tract and nervous system; required for the synthesis of hemoglobin. Due to Biotin deficiency, seborrheic dermatitis, anemia, hair loss, nausea, depression, insomnia, inflammation or pallor of the skin and mucous membranes, loss of appetite, muscle pain, high blood cholesterol can develop.

Biotin is indicated for insufficient production of vitamin H associated with malnutrition, alcohol consumption, dysbacteriosis, long-term use of anticonvulsants and antibiotics; to maintain normal blood sugar levels; in violation of the function of the sebaceous glands of the scalp – with dandruff, brittleness and hair loss; as an adjuvant therapy for muscle weakness, apathy, loss of appetite, drowsiness, dermatitis, chronic fatigue syndrome.

Dosage and administration:

Biotin Complex is taken in prophylactic doses, 2 tablets per day with meals; for therapeutic and prophylactic purposes, it is recommended to double the dosage of the drug. With malabsorption syndrome, it is recommended to take 10 mg. With a hereditary metabolic disease, accompanied by a deficiency of biotinidase, the dose can be increased to 10 mg, with multiple carboxylase deficiency – up to 20 mg. The duration of the course of treatment is 30 days.

Overdose:

No cases of overdose were observed.

Use in pregnancy and lactation

Biotin is contraindicated in pregnancy and lactation.

Side effects and contraindications

Side effects:

When using Biotin, allergic reactions are possible, manifested by skin rashes, swelling of the mucous membrane of the larynx, urticaria, retrosternal pain, which is due to individual intolerance to vitamin components.

Contraindications:

Biotin is contraindicated only in case of individual intolerance to the components that make up the complex, during pregnancy and lactation.