What are the main uses of ciprofloxacin ear drops. How should ciprofloxacin ear drops be properly administered. What are the potential side effects of using ciprofloxacin ear drops. What precautions should be taken when using ciprofloxacin ear drops. How does ciprofloxacin work to treat bacterial ear infections. What drug interactions may occur with ciprofloxacin ear drops. When should a doctor be consulted about ciprofloxacin ear drop usage.

Understanding Ciprofloxacin Ear Drops: A Powerful Treatment for Bacterial Ear Infections

Ciprofloxacin ear drops are a widely prescribed medication for treating bacterial ear infections, particularly conditions like swimmer’s ear and ear canal infections. This potent antibiotic belongs to the quinolone class of drugs and works by inhibiting bacterial growth, effectively combating the infection at its source.

Are ciprofloxacin ear drops suitable for all types of ear infections? No, they are specifically designed to target bacterial infections. It’s crucial to understand that this medication will not be effective against viral or fungal ear infections. Overuse or misuse of antibiotics like ciprofloxacin can lead to decreased effectiveness over time, highlighting the importance of proper diagnosis and prescription by a healthcare professional.

The Science Behind Ciprofloxacin: How It Fights Bacterial Infections

Ciprofloxacin’s mechanism of action is fascinating and highly effective. It targets bacterial DNA gyrase and topoisomerase IV, enzymes crucial for bacterial DNA replication. By interfering with these processes, ciprofloxacin prevents bacteria from reproducing, ultimately leading to their demise.

Why is ciprofloxacin so effective against a wide range of bacteria? Its broad-spectrum activity allows it to combat various bacterial strains commonly found in ear infections. This versatility makes it a go-to choice for many healthcare providers when treating bacterial ear infections.

Proper Administration of Ciprofloxacin Ear Drops: Ensuring Maximum Efficacy

Correct application of ciprofloxacin ear drops is crucial for optimal results. The typical regimen involves administering the drops twice daily, approximately every 12 hours, for a duration of 7 days. However, it’s essential to follow your doctor’s specific instructions, as dosages may vary based on individual cases.

Step-by-Step Guide to Applying Ciprofloxacin Ear Drops

1. Wash your hands thoroughly before handling the medication.
2. Warm the dropper by holding it in your hand for a few minutes to minimize dizziness.
3. Lie on your side or tilt your head with the affected ear facing upward.
4. Gently pull the earlobe up and back for adults (down and back for children) to straighten the ear canal.
5. Carefully empty the contents of the single-use container into the ear canal.
6. Maintain the tilted head position for at least one minute to allow the medication to penetrate.
7. If prescribed, insert a soft cotton plug into the ear.
8. Discard any unused solution after each application to prevent contamination.

Is it necessary to have someone else administer the drops? While not mandatory, having assistance can improve accuracy and reduce the risk of contamination, especially if you have difficulty reaching your ear or maintaining the proper position.

Potential Side Effects: What to Watch For When Using Ciprofloxacin Ear Drops

While ciprofloxacin ear drops are generally well-tolerated, some users may experience side effects. Common reactions include mild discomfort, pain, or itching in the treated ear. These symptoms are usually temporary and often subside as treatment progresses.

More Serious Side Effects to Monitor

• Persistent or worsening ear pain
• Signs of a new infection, such as increased discharge or fever
• Hearing changes or ringing in the ears
• Dizziness or vertigo
• Allergic reactions (rare but serious)

When should you contact your healthcare provider about side effects? If any symptoms persist, worsen, or new concerning symptoms develop, it’s crucial to seek medical advice promptly. In cases of severe allergic reactions, characterized by rash, swelling, or difficulty breathing, immediate medical attention is necessary.

Precautions and Contraindications: Ensuring Safe Use of Ciprofloxacin Ear Drops

Before starting treatment with ciprofloxacin ear drops, it’s essential to discuss your medical history and any current medications with your healthcare provider. This conversation helps identify potential risks and ensures the treatment is safe and appropriate for your specific situation.

Key Precautions to Consider

• Allergies to quinolone antibiotics or other medications
• Pregnancy or breastfeeding status
• History of ear surgeries or perforated eardrums
• Concurrent use of other ear medications or treatments

Can ciprofloxacin ear drops be used during pregnancy? While studies are limited, ciprofloxacin should only be used during pregnancy when the potential benefits outweigh the risks. Consultation with a healthcare provider is crucial to make an informed decision based on individual circumstances.

Drug Interactions: Navigating Potential Complications with Ciprofloxacin Ear Drops

Although ciprofloxacin ear drops are applied locally, it’s important to be aware of potential drug interactions. While systemic absorption is minimal, certain medications or conditions may still pose risks or affect the efficacy of the treatment.

Common Medications to Watch For

• Oral antibiotics, particularly other quinolones
• Corticosteroids
• Blood thinners
• Certain antacids or supplements containing magnesium or aluminum

How can you minimize the risk of drug interactions? Always provide your healthcare provider with a complete list of all medications, supplements, and herbal products you’re currently taking. This information allows for a comprehensive assessment of potential interactions and appropriate adjustments to your treatment plan if necessary.

Long-Term Considerations: Balancing Efficacy and Antibiotic Stewardship

While ciprofloxacin ear drops are highly effective for treating bacterial ear infections, it’s crucial to use them responsibly. Overuse or misuse of antibiotics can lead to antibiotic resistance, a growing concern in the medical community.

Strategies for Responsible Antibiotic Use

• Complete the full course of treatment as prescribed
• Avoid using leftover antibiotics from previous infections
• Do not share antibiotics with others
• Discuss alternative treatments with your healthcare provider for recurrent infections

How can patients contribute to antibiotic stewardship? By following prescription instructions carefully, avoiding unnecessary antibiotic use for viral infections, and engaging in open dialogue with healthcare providers about antibiotic use, patients play a crucial role in preserving the effectiveness of important medications like ciprofloxacin.

Beyond Treatment: Preventing Future Ear Infections

While ciprofloxacin ear drops effectively treat bacterial ear infections, prevention is always preferable. Understanding the risk factors and implementing preventive measures can significantly reduce the likelihood of future infections.

Effective Prevention Strategies

• Keep ears dry after swimming or bathing
• Avoid inserting foreign objects into the ear canal
• Manage allergies and upper respiratory infections promptly
• Consider using ear plugs or swim caps when swimming
• Maintain good overall ear hygiene

Can lifestyle changes significantly reduce the risk of ear infections? Absolutely. Many ear infections, particularly swimmer’s ear, are preventable with proper care and attention to ear health. Implementing these preventive measures can greatly reduce the need for antibiotic treatments in the future.

Special Populations: Considerations for Children and Elderly Patients

While ciprofloxacin ear drops are generally safe for use in adults, special considerations may apply to certain populations, particularly children and elderly patients. These groups may have unique risk factors or require modified treatment approaches.

Pediatric Use of Ciprofloxacin Ear Drops

Children may be more susceptible to ear infections due to their anatomy and developing immune systems. When prescribing ciprofloxacin ear drops for pediatric patients, healthcare providers carefully consider factors such as:

• Age-appropriate dosing
• Potential impact on cartilage development
• Alternative treatment options for recurrent infections

Are there any age restrictions for using ciprofloxacin ear drops in children? While ciprofloxacin is approved for use in children, the specific age range may vary depending on the formulation and local guidelines. Always consult with a pediatrician for the most appropriate treatment option for your child.

Geriatric Considerations

Elderly patients may face unique challenges when using ciprofloxacin ear drops, including:

• Increased risk of dizziness or balance issues
• Potential interactions with multiple medications
• Changes in ear anatomy that may affect drug absorption

How can healthcare providers ensure safe use of ciprofloxacin ear drops in elderly patients? Careful assessment of overall health, medication regimens, and potential risk factors is crucial. Providers may consider lower doses or alternative treatments if concerns arise.

Emerging Research: The Future of Ear Infection Treatments

While ciprofloxacin ear drops remain a cornerstone in treating bacterial ear infections, ongoing research continues to explore new treatment options and improvements to existing therapies. These advancements aim to enhance efficacy, reduce side effects, and combat the growing concern of antibiotic resistance.

Promising Areas of Research

• Novel antibiotic formulations with improved penetration
• Combination therapies to enhance effectiveness
• Non-antibiotic treatments for certain types of ear infections
• Targeted drug delivery systems for more precise treatment

How might future treatments change the landscape of ear infection management? Emerging research holds the potential to revolutionize treatment approaches, potentially offering more personalized, effective, and resistance-resistant options for patients suffering from ear infections.

Patient Education: Empowering Informed Decision-Making

Effective treatment with ciprofloxacin ear drops relies not only on proper administration but also on patient understanding and compliance. Educating patients about their condition, treatment options, and the importance of following medical advice is crucial for optimal outcomes.

Key Points for Patient Education

• Understanding the difference between bacterial and viral ear infections
• Recognizing signs of improvement or worsening symptoms
• Proper technique for administering ear drops
• Importance of completing the full course of treatment
• Awareness of potential side effects and when to seek medical attention

How can healthcare providers effectively communicate complex medical information to patients? Utilizing a combination of verbal explanations, written materials, and visual aids can help ensure patients fully understand their treatment plan and the importance of adherence.

Alternative Treatments: When Ciprofloxacin Isn’t the Answer

While ciprofloxacin ear drops are highly effective for many bacterial ear infections, they may not be suitable for all patients or situations. Understanding alternative treatment options is essential for comprehensive patient care.

Potential Alternatives to Ciprofloxacin Ear Drops

• Other antibiotic ear drops (e.g., ofloxacin, neomycin)
• Oral antibiotics for more severe or systemic infections
• Antifungal treatments for fungal ear infections
• Pain relief medications for symptom management
• Watchful waiting for mild cases that may resolve on their own

When should alternative treatments be considered? Factors such as allergies, antibiotic resistance, recurrent infections, or specific pathogen types may necessitate exploring alternative treatment options. A thorough evaluation by a healthcare provider is crucial in determining the most appropriate course of action.

The Role of Follow-Up Care in Ear Infection Treatment

Proper follow-up care is an integral part of successful treatment with ciprofloxacin ear drops. It allows healthcare providers to assess treatment efficacy, monitor for potential complications, and make necessary adjustments to the treatment plan.

Key Components of Follow-Up Care

• Scheduled check-ups to evaluate symptom improvement
• Hearing tests to assess any impact on auditory function
• Discussion of any side effects or concerns
• Guidance on preventing future infections
• Consideration of further testing if symptoms persist

How soon after starting treatment should patients schedule a follow-up appointment? While this may vary based on individual cases, a general guideline is to follow up within 7-10 days of starting treatment with ciprofloxacin ear drops. However, patients should seek immediate care if symptoms worsen or new concerns arise during treatment.

Ciprofloxacin Ear Drops in the Context of Antibiotic Resistance

The global concern of antibiotic resistance adds an important dimension to the use of ciprofloxacin ear drops. While these drops remain highly effective for many patients, understanding their place in the broader context of antibiotic stewardship is crucial for both healthcare providers and patients.

Strategies for Mitigating Antibiotic Resistance

• Reserving antibiotic use for confirmed bacterial infections
• Utilizing narrow-spectrum antibiotics when possible
• Emphasizing the importance of completing full treatment courses
• Implementing regular surveillance of local resistance patterns
• Exploring combination therapies to enhance effectiveness

How can patients contribute to the fight against antibiotic resistance? By following prescription instructions carefully, avoiding unnecessary antibiotic use for viral infections, and engaging in open dialogue with healthcare providers about antibiotic use, patients play a crucial role in preserving the effectiveness of important medications like ciprofloxacin.

In conclusion, ciprofloxacin ear drops remain a valuable tool in treating bacterial ear infections. Their effectiveness, when used appropriately, can provide rapid relief and prevent complications. However, responsible use, careful monitoring, and consideration of alternative treatments when necessary are essential components of optimal ear infection management. By staying informed and working closely with healthcare providers, patients can navigate the complexities of ear infection treatment and maintain optimal ear health.

Ciprofloxacin Otic (Ear): Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Uses

Ciprofloxacin is used to treat bacterial ear infections (swimmer’s ear or ear canal infections). It works by stopping the growth of bacteria. This medication belongs to a class of drugs called quinolone antibiotics.This medication treats only bacterial ear infections. It will not work for other types of ear infections. Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness.

How to use Ciprofloxacin Hcl Dropperette, Single Use Dropper

Learn all preparation and usage instructions before using this medication. For accuracy and to avoid contamination, have another person give the drops if possible. Hold the container in your hand for a few minutes to warm it. This will minimize dizziness. Wash your hands before opening/using the medication. To avoid contamination, do not touch the dropper tip or let it touch your ear or any other surface.

Use this medication in the infected ear as directed by your doctor, usually twice daily (every 12 hours) for 7 days. Use in the ear only. Do not use in the eyes, inject, or inhale the medication.

Lie on your side or tilt your head with the ear to be treated facing upward. Hold the container directly over the ear, and empty the contents of the single-use container into the ear canal. While placing the solution into the ear of an adult, the earlobe should be gently pulled up and back to allow the drops to flow down into the ear canal. For children, gently pull the earlobe down and back. Keep the head tilted with the treated ear upward for at least 1 minute or insert a soft cotton plug if so directed. Discard any unused solution after each application. Do not reuse.

Repeat the above steps for the other ear if so directed.

Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same times each day. Continue using it for the full time prescribed, even if symptoms disappear after a few days. Stopping this medication too early may allow bacteria to continue to grow, which may result in a return of the infection.

Inform your doctor if your condition lasts or gets worse after 7 days of treatment.

Side Effects

Discomfort, pain, or itching in the ear may occur. If any of these effects last or get worse, notify your doctor or pharmacist promptly.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Use of this medication for prolonged or repeated periods may result in a new bacterial/fungal ear infection. Do not use this medication for longer than prescribed. Contact your doctor if you notice new or worsening symptoms.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before using this medication, tell your doctor or pharmacist if you are allergic to it or to other quinolone antibiotics (such as ofloxacin, levofloxacin), or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if ciprofloxacin in this ear drop passes into breast milk. Consult your doctor before breast-feeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

Does Ciprofloxacin Hcl Dropperette, Single Use Dropper interact with other drugs you are taking?

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Overdose

This medicine may be harmful if swallowed. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Do not share this medication with others.

This medication has been prescribed for your current condition only. Throw away the unused medication after treatment is completed. Do not use it later for another infection unless your doctor tells you to.

It is important to keep the infected ear(s) clean and dry. Try not to get the infected ear(s) wet when bathing. Avoid swimming unless your doctor tells you otherwise.

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.

Store at room temperature in the original pouch to protect from light. Do not freeze. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

Ciprofloxacin Otic: MedlinePlus Drug Information

pronounced as (sip roe flox’ a sin)

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Ciprofloxacin otic solution (Cetraxal) and ciprofloxacin otic suspension (Otiprio) are used to treat outer ear infections in adults and children. Ciprofloxacin otic suspension (Otiprio) is also used in children during ear tube placement surgery to prevent infection or ear drainage. Ciprofloxacin otic is in a class of medications called quinolone antibiotics. It works by killing the bacteria that cause infection.

Ciprofloxacin otic (Cetrexal) comes as a solution (liquid) to place into the ear. It is usually used twice a day for 7 days. Use ciprofloxacin otic solution at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use ciprofloxacin otic exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

Ciprofloxacin otic (Otiprio) also comes as a suspension (liquid) to be placed into the ear by a doctor or nurse in a doctor’s office or other medical facility. Ciprofloxacin otic suspension (Otiprio) is usually given as a single dose.

Ciprofloxacin otic is only for use in the ears. Do not use in the eyes.

You should begin to feel better during the first few days of treatment of out ear infections with ciprofloxacin otic. If your symptoms do not improve after one week or get worse, call your doctor. Also, call your doctor if you have ear pain, continuous ear discharge, or fever following use during ear tube surgery.

Ciprofloxacin otic (Cetrexal) ear drops come in single-use containers (small bottles to be used for one dose). Use the liquid from the container immediately after opening, and throw away the container when you are finished. Use ciprofloxacin otic ear drops until you finish the prescription, even if you feel better. If you stop using ciprofloxacin otic too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.

To use the eardrops, follow these steps:

1. Wash your hands thoroughly.
2. Hold the container in your hand for at least 1 minute to warm the solution.
3. Twist off the top of the container.
4. Lie down with the affected ear upward.
5. Place the entire contents of the container into your ear.
6. Remain lying down with the affected ear upward for at least 60 seconds.
7. Repeat steps 1-6 for the opposite ear if necessary.
8. Throw away the empty container(s) in a trash can.

Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before using ciprofloxacin otic,

• tell your doctor and pharmacist if you are allergic to ciprofloxacin (Cipro), gemifloxacin (Factive), levofloxacin (Levaquin), lomefloxacin (Maxaquin), moxifloxacin (Avelox), nalidixic acid (NegGram), norfloxacin (Noroxin), ofloxacin (Floxin), any other medications, or any of the ingredients in ciprofloxacin otic. Ask your doctor or pharmacist for a list of the ingredients.
• tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.
• tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while using ciprofloxacin otic, call your doctor.
• you should know that you must keep your infected ear(s) clean and dry while using ciprofloxacin otic. Avoid getting the infected ear(s) wet while bathing, and avoid swimming unless your doctor has told you otherwise.

Unless your doctor tells you otherwise, continue your normal diet.

Apply the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not use extra eardrops to make up for a missed one.

Ciprofloxacin otic may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• ear discomfort, pain, or itching

Some side effects can be serious. If you experience any of these symptoms, stop using ciprofloxacin otic and call your doctor immediately

• rash
• hives
• swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
• hoarseness
• difficulty swallowing or breathing

Ciprofloxacin otic may cause other side effects. Call your doctor if you have any unusual problems while using this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light, excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA’s Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

• Cetraxal^®
• Otiprio^®

Last Revised – 05/15/2018

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Dosage, side effects, active substance, composition

THERE ARE CONTRAINDICATIONS. POSSIBLE SIDE EFFECTS. A SPECIALIST’S CONSULTATION IS REQUIRED.Antibiotics in tablets SinusitisPyelonephritisProstatitisCystitis

Author of the article

Podoinitsyna Alena Andreevna,

Diploma of pharmaceutical education: 105924 351072 2 reg. number 31917

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Contents of the article

• Ciprofloxacin: active ingredient
• Ciprofloxacin: indications for use
• Ciprofloxacin: dosage
• Ciprofloxacin: side effects
• Ciprofloxacin and alcohol: compatibility
• Ciprofloxacin or Levofloxacin: which is better
• Summary
• Ask an expert on the topic of the article

Sore throat worse when swallowing, fever and chills, body aches – all these are signs of a sore throat or, in other words, acute tonsillitis. In cases where the throat is covered with a yellowish-white purulent coating, and the cervical lymph nodes are enlarged, we can talk about the bacterial nature of the disease. In such a situation, the only possible treatment is antibacterial drugs. One of them will be discussed in the article.

Alena Podoinitsyna, a pharmacist, will tell you about Ciprofloxacin: introduce its active ingredient, indications for use, contraindications, and compare it with its analogue – Levofloxacin.

Ciprofloxacin: active ingredient

Ciprofloxacin is an antimicrobial agent with the active ingredient of the same name. The drug has a bactericidal effect against a number of bacteria. In other words, it causes their death.

According to the State Drug Registry or State Drug Administration: Ciprofloxacin is produced in several dosage forms: tablets, intravenous solution, eye and ear drops. There is no such form as Ciprofloxacin ointment.

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Ciprofloxacin: indications for use

Ciprofloxacin tablets and solution for infusion are used to treat infections caused by susceptible microorganisms. These can be infections of the respiratory tract, middle ear, eyes, kidneys, urinary tract and other organs. If we talk about specific diseases of a bacterial nature, then Ciprofloxacin is prescribed:

Ciprofloxacin has contraindications. For example, hypersensitivity to the components of the drug, simultaneous use with certain drugs and children’s age. In addition, the use of Ciprofloxacin during pregnancy is contraindicated.

Ciprofloxacin: dosage

The daily dose and duration of administration is determined by the doctor based on the type of disease and the severity of its symptoms. For example, for the treatment of uncomplicated respiratory tract infections, ciprofloxacin 500 mg 2 times a day is usually prescribed.

Ciprofloxacin side effects

Ciprofloxacin causes the following side effects:

• Eosinophilia – increased number of eosinophils – blood cells
• Allergic reactions: urticaria, skin rash, angioedema
• Loss of appetite
• Psychomotor hyperactivity
• Headache and dizziness
• Sleep and taste disorders
• Visual disorders
• Tinnitus
• Palpitations
• Respiratory failure
• Nausea and diarrhea
• Increased activity of liver enzymes
• Joint pain
• Renal disorders
• Pain syndrome of non-specific etiology

Ciprofloxacin and alcohol compatibility

Do not take ciprofloxacin and alcohol together. This combination will minimize the effectiveness of the drug, which means that the bacteria will continue to grow and multiply. In addition, it is possible to increase adverse reactions: a detrimental effect on the liver and intestinal microflora or a disruption in the functioning of the nervous system.

Ciprofloxacin or Levofloxacin: which is better

Levofloxacin is a synthetic antimicrobial agent belonging to the same group as Ciprofloxacin. It is produced in the form of tablets, solution for intravenous administration and eye drops.

The spectrum of antimicrobial activity of Levofloxacin is wider. For example, the drug is effective against Staphylococcus aureus and chlamydia. Ciprofloxacin, due to its mechanism of action, causes bacterial resistance or resistance more often than other drugs.

You cannot choose which drug is better: Ciprofloxacin or Levofloxacin. The final decision on the appointment of a particular drug is made by the doctor.

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Summary

• Ciprofloxacin is an antimicrobial agent with the same active ingredient.
• Ciprofloxacin tablets and solution for infusion are used for infections caused by susceptible organisms.
• Daily doses and duration of administration are determined by the doctor based on the type of disease and the severity of its symptoms.
• Do not take ciprofloxacin and alcohol together.
• It is impossible to choose which drug is better: Ciprofloxacin or Levofloxacin.

Ask an expert about the topic of the article

Still have questions? Ask them in the comments below and our experts will answer you. There you can also share your experience with other readers of Megasovets.

Editor-in-chief

Zotina Natalya Igorevna,

Expert pharmacist

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instructions for use, price, analogues, composition, indications

Clear, colorless or slightly greenish solution.

Per vial:

active substance: ciprofloxacin (as ciprofloxacin hydrochloride) – 15.0 mg;

excipients: mannitol (mannitol), benzalkonium chloride, sodium acetate trihydrate, disodium edetate (E 386), glacial acetic acid, water for injection.

Means used in ophthalmology.

Antimicrobial agents.

ATC code: S01AE03.

Antimicrobial drug. Acts bactericidal. While taking ciprofloxacin, there is no parallel development of resistance to aminoglycosides, penicillins, cephalosporins, tetracyclines. Ciprofloxacin has shown high activity in in vitro studies against many gram-negative microorganisms, including Pseudomonas aeruginosa. It is also effective against gram-positive bacteria such as staphylococci and streptococci. Anaerobic bacteria are generally less sensitive.

In vitro and in vivo studies have established the activity of ciprofloxacin against the following microorganisms (MIC ≤ 1 μg / ml):

Gram-positive: Staphylococcus aureus (methicillin-susceptible), Staphylococcus epidermidis (methicillin-susceptible), Streptoc occus pneumoniae, Streptococcus ( group Viridans).

Gram-negative: Acinetobacter sp., Haemophilus sp., Pseudomonas aeruginosa, Serratia marcescens.

In vitro studies have established the activity of ciprofloxacin against most strains of the following microorganisms, although the clinical significance of these data has not been established:

Gram-positive: Bacillus cereus, Corynebacterium sp., Enterococcus faecalis (many strains are moderately susceptible), Micrococcus sp., Staphylococcus capitis, Staphylococcus haemolyticus, Staphylococcus hominis, Staphylococcus saprophyticus, Sta phylococcus warneri, Streptococcus pyogenes.

Gram-negative: Aeromonas caviae, Aeromonas hydrophila, Brucella melitensis, Campylobacter coli, Campylobacter jejuni, Citrobacter sp., Edwardsiella tarda, Enterobacter sp., Escherichia coli, Haemophil us parainfluenzae, Klebsiella pneumoniae, Klebsiella oxytoca, Legionella pneumophila, Moraxella sp. , Morganella morganii, Neisseria gonorrhoeae, Neisseria meningitides, Pasteurella multocida, Proteus mirabilis, Proteus vulgaris, Providencia sp., Salmonella enteritidis, Salmonella typhi, Shigella sonneii, Shigella flexneri, Vibrio cholera, Vibrio parahaemolyticus, Vibrio vulnific us, Yersinia enterocolitica.

Other organisms: Chlamydia trachomatis and Mycobacterium only moderately sensitive (MIC > 1 µg/mL, < 9014 4 2 µg/ml) . Most strains of Pseudomonas cepacia and some strains of Pseudomonas maltophilia are resistant to ciprofloxacin, as are most anaerobic bacteria, including Bacteroides fragilis and Clostridium difficile (MIC > 4 µg/ml) .

Controlled clinical trials to study the effectiveness of the drug in chlamydial infection have not been conducted. Therefore, the drug is not suitable for the treatment of chlamydial infection.

Superficial infectious and inflammatory diseases of the eyes, such as conjunctivitis, blepharitis and blepharoconjunctivitis; bacterial corneal ulcers caused by microorganisms susceptible or suspected to be susceptible to ciprofloxacin, in particular Pseudomonas aeruginosa and other gram-negative pathogens resistant to standard treatments.

– wash your hands before instillation;

– tilt your head back;

– lower the edge of the lower eyelid with your finger until a “pocket” is formed between the eyelid and your eye;

– without touching the eye or eyelid, adjacent areas or other surfaces with parts of the dropper, drop the drug into the formed “pocket” in the amount of kazel indicated in the instructions;

– if necessary, repeat the steps for the other eye;

– if you missed the time of instillation, do not use a double dose, just use the drug when the next time comes;

– if you accidentally instill more ciprofloxacin than required according to the instructions, rinse your eyes with warm water.

Adults and children over 1 year:

Superficial bacterial infections of the eye and its appendages (bacterial conjunctivitis/blepharitis):

– 1 – Day 2: 1-2 drops during the day every 2 hours into the conjunctival sac of inflamed eyes;

– 3 – Day 7: every 4 hours, 1-2 drops are instilled into the conjunctival sac of inflamed eyes.

If longer treatment is required, the dose is determined by the doctor.

In case of a bacterial corneal ulcer, 2 drops of the drug are instilled every 15 minutes for 6 hours, then 2 drops every 30 minutes during waking hours on the 1st day; on the 2nd day – 2 drops every hour during waking hours; from 3 to 14 days – 2 drops every 4 hours during waking hours. If after 14 days of therapy epithelialization has not occurred, treatment can be continued.

The maximum duration of treatment for any of the diagnoses is 21 days.

Elderly patients. The efficacy and safety of ciprofloxacin eye drops do not differ between older and younger patients.

Children. For children under 1 year of age, the safety and efficacy of the medicinal product has not been established. Although oral ciprofloxacin and other fluoroquinolones cause arthropathy in young animals, ciprofloxacin does not cause arthropathy when instilled into the eye, and there is no evidence of an effect of ophthalmic doses on the supporting joints of young animals.

Allergic reactions, itching, burning, mild soreness and hyperemia of the conjunctiva, nausea; rarely – swelling of the eyelids, photophobia, lacrimation, sensation of a foreign body in the eyes, an unpleasant aftertaste in the mouth immediately after instillation, decreased visual acuity, the appearance of a white crystalline precipitate in patients with a corneal ulcer, keratitis, keratopathy, the appearance of spots or infiltration of the cornea, the development of superinfection, prolongation of the QT interval on the electrocardiogram.

In case of adverse reactions, including those not listed in this leaflet, you should consult a doctor.

Hypersensitivity to ciprofloxacin or other drugs of the quinolone group, hypersensitivity to the auxiliary components of the drug, viral and fungal eye lesions, glucose-6-phosphate dehydrogenase deficiency, pregnancy and lactation (breastfeeding should be stopped for the period of treatment), children under 1 year of age ( for eye drops).

There are no data on drug overdose.

In case of an overdose of the drug when applied topically, the excess solution should be removed by rinsing the eyes with plenty of warm running water.

After instillation of the solution into the eyes to reduce systemic absorption, it is recommended:

– hold the eyelid closed for 2 minutes;

– squeeze the tear duct with your finger for 2 minutes.

This medicine contains benzalkonium chloride, which may cause eye irritation.

Since hypersensitivity reactions cannot be excluded during treatment, the drug should be discontinued at the first sign of redness or other symptoms of hypersensitivity.

Do not use the drug for infections associated with deeper structures of the eye.

Serious, life-threatening anaphylactic-type hypersensitivity reactions have been reported following systemic administration of quinolones. Reactions are manifested by cardiovascular disorders, loss of consciousness, swelling of the pharynx or face, shortness of breath, urticaria and itching. Only a small proportion of these patients had a history of hypersensitivity reactions. Serious anaphylactic reactions require immediate emergency care with the introduction of adrenaline and other resuscitation measures.

As with other antibacterial agents, long-term use of ciprofloxacin may lead to the development and growth of resistant strains of bacteria or fungi. In case of superinfection, appropriate therapy should be initiated.

When prescribing eye drops containing antimicrobial agents, one should take into account the possible nasopharyngeal passage, which can lead to the development and spread of bacterial resistance.

The drug can only be applied topically; it should not be injected subconjunctivally or directly into the anterior chamber of the eye. When using other ophthalmic drugs, the interval between their administration should be at least 15 minutes.

During treatment with the drug, it is not recommended to wear soft contact lenses. When using hard contact lenses, remove them before instillation and put them back on 15-20 minutes after instillation of the drug.

The bottle must be closed after each use. Do not touch the tip of the pipette to the eye.

The drug should be used with caution in patients with cerebral atherosclerosis, cerebrovascular accident, convulsive syndrome, with known risk factors for prolongation of the QT interval.

Patients should be aware that if conjunctival hyperemia continues or increases after the use of drops for a long time, stop using the drug and consult a doctor.

Use during pregnancy and lactation

The use of the drug during pregnancy and lactation is contraindicated (breastfeeding should be stopped for the period of treatment).

Influence on the ability to drive vehicles and other potentially dangerous mechanisms

Patients who temporarily lose their vision after using ciprofloxacin eye drops should not drive a car or work with complex equipment immediately after instillation of the drug.

Studies on the interaction of ciprofloxacin in the form of eye drops with other drugs have not been conducted. With the systemic administration of some quinolones, an increase in the plasma concentration of theophylline, an effect on the metabolism of caffeine, and an increase in the effects of oral anticoagulants, warfarin and its derivatives were observed. In addition, there was a transient increase in serum creatinine in patients who simultaneously received cyclosporine.

Incompatibilities: ciprofloxacin eye drops are incompatible with alkaline solutions.

Store in a place protected from light at a temperature not exceeding 25 ° C.

Store the opened vial in a place protected from light at a temperature of 15 ° C to 25 ° C for 4 weeks.

Keep out of the reach of children.

Do not use the medicine after the expiration date.

2 years.

5 ml in glass vials. One bottle, complete with a dropper cap and instructions for use, is placed in a cardboard box.