Major Docusate Sodium 100 mg

Now:

$5.99

UPC:

309046998600

Generic Equivalent:

Colace Regular Strength Stool Softener

Expiration Date:

10-2024

Current Stock:
16

Quantity:

Adding to cart… The item has been added

Product Overview

Major Docusate Sodium 100 mg – 100 Softgels (Colace Regular Strength Stool Softener)

• Compare to the active ingredient in Colace Regular Strength Stool Softener
• Stool softener laxative

Expiration Date: 10-2024

Ingredients

• Active: Docusate Sodium 100mg – Stool softener laxative
• Inactive: Edible Ink, FD&C Red #40, FD&C Yellow #6, Gelatin, Glycerin, Polyethylene Glycol, Propylene Glycol, Purified Water Sorbitan, Sorbitol 

Uses

• Relieves occasional constipation (irregularity)
• Generally produces bowel movement in 12 to 72 hours 

FULL DESCRIPTION

Drug Facts

Active Ingredients (in each softgel)

• Docusate Sodium – 100 mg
• Purpose: Stool softener laxative 

Uses

• Relieves occasional constipation (irregularity)
• Generally produces bowel movement in 12 to 72 hours 

Warnings

• Do Not Use
• If you are presently taking mineral oil, unless told to do so by a doctor

• Ask a Doctor Before Use if You Have
• Stomach pain
• Nausea
• Vomiting
• Noticed a sudden change in bowel habits that last over 2 weeks

• Stop Use and Ask a Doctor If
• You have rectal bleeding or fail to have a bowel movement after use of a laxative
• These could be signs of a serious condition
• You need to use a laxative for more than 1 week

• If Pregnant or Breast-Feeding
• Ask a health professional before use

• Keep Out of Reach of Children
• In case of overdose, get medical help or contact a Poison Control Center right away

Directions

• Take only by mouth
• Doses may be taken as a single daily dose or in divided doses
• Adults and children 12 years and over 
• Take 1 to 3 softgels daily

• Children 2 to under 12 years of age
• Take 1 softgel daily

• Children under 2 years
• Ask a doctor

Other Information

• Each softgel contains: Sodium 5mg
• Store at 25ºC (77ºF)
• Excursions permitted between 15º-30ºC (59º-86ºF)

Inactive 

• Edible Ink, FD&C Red #40, FD&C Yellow #6, Gelatin, Glycerin, Polyethylene Glycol, Propylene Glycol, Purified Water Sorbitan, Sorbitol

Colace: Side Effects, Uses, & Dosage

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Generic name: docusate [ DOK-ue-sate ]
Drug class: Laxatives

Medically reviewed by Philip Thornton, DipPharm. Last updated on Mar 3, 2022.

What is Colace?

Colace is a stool softener. It makes bowel movements softer and easier to pass.

Colace is used to treat or prevent occasional constipation, and to reduce pain or rectal damage caused by hard stools or by straining during bowel movements.

Colace may also be used for purposes not listed in this medication guide.

Warnings

You should not use Colace if you have a blockage in your intestines.

Do not use Colace while you are sick with nausea, vomiting, or severe stomach pain.

You should not use docusate if you also use mineral oil, unless your doctor tells you to.

Before taking this medicine

You should not use Colace if you are allergic to docusate.

Ask a doctor or pharmacist if this medicine is safe to use if you have:

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

Do not give this medicine to a child without medical advice.

How should I use Colace?

Use Colace exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Take this medicine with a full glass of water. Drink plenty of liquids while you are taking this medicine.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Colace generally produces bowel movement in 12 to 72 hours. Call your doctor if your symptoms do not improve after 72 hours.

You should not use this medicine for longer than 1 week, unless your doctor tells you to. Call your doctor if your symptoms do not improve, or if you have not had a bowel movement within 1 to 3 days. Overuse of a stool softener can lead to serious medical problems.

Store at room temperature away from moisture, light, and heat. Do not freeze liquid medicine.

Dosing information

Usual Adult Dose for Constipation:

50 to 300 mg daily divided in 1 to 4 doses each day.

Usual Pediatric Dose for Constipation:

Less than 2 years: Check with your doctor.

2 to 12 years: 50 to 150 mg daily divided in 1 to 4 doses each day.

What happens if I miss a dose?

Since Colace is used when needed, you may not be on a dosing schedule. Skip any missed dose if it’s almost time for your next dose. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Colace?

Avoid using mineral oil, unless told to do so by a doctor.

Colace side effects

Get emergency medical help if you have signs of an allergic reaction to Colace : hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if:

• you have rectal bleeding;

• no bowel movement occurs after using a laxative;

• you need to use a stool softener for more than 1 week; or

• if a rash occurs.

Less serious Colace side effects may be more likely, and you may have none at all.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Colace?

Other drugs may interact with docusate, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Popular FAQ

Any drug that is classified as an “opioid” can cause constipation. Examples of commonly prescribed opioids that may cause this side effect include morphine, tramadol, fentanyl, methadone, hydrocodone, codeine and oxycodone. Continue reading

More FAQ

• What is the maximum dosage for Colace stool softener at one time?

References

1. Colace Product Label

More about Colace (docusate)

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• During pregnancy
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• Drug class: laxatives
• Breastfeeding
• En español

Patient resources

• Patient Information
• Colace (Docusate Liquid and Syrup)

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Professional resources

• Prescribing Information

Other formulations

• Peri-Colace
• Colace Microenema

Related treatment guides

• Constipation

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Colace only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Copyright 1996-2023 Cerner Multum, Inc. Version: 5.01.

E952 – Sodium cyclamate | Additives no

Other additive names (synonyms)

sodium cyclamate, sodium cyclamate, cyclamic acid and its sodium, potassium and calcium salts, sodium cyclamate, cyclamic acid and Ca salts

Additive E952, better known as sodium cyclamate, is used in the food industry as a sweetener. This chemical is ten times sweeter than sugar. Some people find foods with sodium cyclamate unpleasant to the taste.

Chemically speaking, E952 is cyclamic acid and its sodium, potassium and calcium salts. The chemical formula of sodium cyclamate is C ₆ H ₁₂ S ₃ NNaO.

Additive E952 is prepared by sulfonation from cyclohexylamine. The cyclamate formation reaction is achieved by reacting cyclohexylamine with sulfamic acid or sulfur trioxide.

Cyclamate was discovered in 1937 at the University of Illinois by graduate student Michael Sveda. The graduate student worked in the laboratory for the synthesis of an antipyretic agent. He accidentally dipped a cigarette into the preparation, and when he took it back into his mouth, he discovered the sweet taste of cyclamate.

The patent for cyclamate was acquired by DuPont but later sold to Abbott Laboratories, which did the necessary research and introduced the new drug in 1950. Initially, Abbott intended to use cyclamate to mask the bitterness of certain drugs, such as antibiotics and pentobarbital. In 1958, cyclamate was recognized as a safe food supplement in the United States. Cyclamate was sold in tablet form for use by diabetic patients as an alternative to sugar.

However, at 1966 studies have shown that some intestinal bacteria can break down cyclamate to form cyclohexylamine, which in turn can be toxic to some living organisms. Further studies in rats in 1969 showed that cyclamate promotes the development of bladder cancer. Following these studies, the FDA banned the use of cyclamate in the US. Since then, Abbott has repeatedly petitioned the FDA to lift the ban on cyclamate, arguing that it is safe. However, to date, the addition of E952 remains banned for use in the US food industry.

Most experts now believe that the E952 supplement does not directly cause cancer, but may increase the effect of other carcinogens.

Additive E952 is not absorbed by the body of most people and animals and is excreted in the urine. The safe daily dose of sodium cyclamate is 10 mg per 1 kg of body weight. At the same time, a number of people in the intestines have bacteria that process sodium cyclamate with the formation of conditionally teratogenic metabolites. Therefore, the use of products with the addition of E9 is not recommended.52 pregnant women.

The most commonly used mixture in food products is 10 parts cyclamate and 1 part saccharin. Often cyclamate is used in low-calorie drinks, diabetic products. Sweetener E952 is stable when heated, which allows it to be used in confectionery and hot instant drinks.

Despite the potential health risks, E952 is now approved for use as a sweetener in more than 55 countries. Cyclamate is included in the list of permitted food additives in Ukraine. In the Russian Federation, sodium cyclamate was excluded from the list of approved food additives on December 23, 2010.

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