What are the primary uses of Coreg (carvedilol). How does carvedilol work to treat heart conditions. What are the common side effects of Coreg 25mg. How should patients take Coreg for optimal results. What precautions should be considered before starting carvedilol treatment.

Understanding Carvedilol: A Powerful Cardiovascular Medication

Carvedilol, commonly known by its brand name Coreg, is a versatile medication used in the treatment of various cardiovascular conditions. This alpha and beta blocker plays a crucial role in managing high blood pressure, heart failure, and improving survival rates after heart attacks. But how exactly does this drug work, and what should patients know about its effects?

The Mechanism of Action: How Carvedilol Works

Carvedilol’s effectiveness stems from its unique dual-action mechanism. It blocks the effects of certain natural substances in the body, such as epinephrine, on the heart and blood vessels. This action results in several beneficial outcomes:

• Lowering heart rate
• Reducing blood pressure
• Decreasing strain on the heart

By modulating these cardiovascular parameters, carvedilol helps to alleviate symptoms and improve overall heart function in patients with various cardiac conditions.

Primary Uses of Coreg: Addressing Multiple Cardiovascular Concerns

Carvedilol’s versatility makes it a valuable tool in the treatment of several heart-related issues. What are the main conditions that Coreg is prescribed for?

1. Hypertension (High Blood Pressure): Coreg effectively lowers blood pressure, reducing the risk of strokes, heart attacks, and kidney problems.
2. Heart Failure: The medication helps manage symptoms and improve heart function in patients with chronic heart failure.
3. Post-Heart Attack Care: Carvedilol is used to enhance survival rates in patients whose hearts are not pumping efficiently after a heart attack.

This wide range of applications underscores the importance of carvedilol in modern cardiovascular medicine.

Proper Administration: How to Take Coreg for Optimal Results

To maximize the benefits of carvedilol while minimizing potential side effects, it’s crucial to follow the prescribed dosage and administration guidelines. How should patients take Coreg?

• Take the medication orally with food, typically twice daily
• Follow your doctor’s instructions regarding dosage, which is based on your medical condition and response to treatment
• Start with a low dose, gradually increasing as directed by your healthcare provider
• Maintain a consistent schedule, taking the medication at the same times each day

It’s important to note that the full benefits of carvedilol may take 1 to 2 weeks to manifest, particularly in the treatment of high blood pressure. Patients should continue taking the medication as prescribed, even if they feel well.

Common Side Effects of Coreg 25mg: What to Expect

While carvedilol is generally well-tolerated, like all medications, it can cause side effects. What are the most common side effects associated with Coreg 25mg?

• Dizziness
• Lightheadedness
• Drowsiness
• Diarrhea
• Impotence
• Fatigue

These side effects are typically mild and often subside as the body adjusts to the medication. However, if these effects persist or worsen, it’s important to consult with a healthcare provider promptly.

Managing Side Effects: Practical Tips

To minimize the risk of dizziness and lightheadedness, patients should:

• Rise slowly from sitting or lying positions
• Be particularly cautious within the first hour after taking the medication
• Take Coreg with food as prescribed
• Follow the gradual dose increase schedule set by their doctor

Additionally, carvedilol may reduce blood flow to the extremities, causing cold hands and feet. Patients are advised to dress warmly and avoid tobacco use, which can exacerbate this effect.

Serious Side Effects: When to Seek Medical Attention

While most side effects of carvedilol are mild, some can be more serious and require immediate medical attention. What are the signs that warrant contacting a healthcare provider?

• Very slow heartbeat
• Severe dizziness or fainting
• Unusual weakness
• Signs of kidney problems (changes in urine output)
• Numbness or tingling in hands or feet
• Blue discoloration of fingers or toes
• Easy bruising or bleeding
• Mental or mood changes (confusion, depression)
• Seizures

In rare cases, some patients may experience new or worsening symptoms of heart failure, particularly when starting carvedilol treatment. It’s crucial to report any of the following symptoms to a doctor immediately:

• Shortness of breath
• Swelling in ankles or feet
• Unusual tiredness
• Sudden weight gain

Precautions and Considerations: Ensuring Safe Use of Carvedilol

Before starting carvedilol treatment, it’s essential to provide a comprehensive medical history to your healthcare provider. What factors should be considered before taking Coreg?

• Allergies to carvedilol or other medications
• History of certain heart rhythm problems
• Breathing issues (asthma, chronic bronchitis, emphysema)
• Severe heart failure requiring hospitalization
• Liver or kidney disease
• Blood circulation problems
• Thyroid disorders
• Diabetes
• Planned surgeries

Patients should also inform their doctor about all current medications, including over-the-counter drugs and supplements, to avoid potential interactions.

Special Considerations for Specific Patient Groups

Certain patient populations require extra caution when using carvedilol:

• Pregnant women: Carvedilol should only be used during pregnancy if clearly needed, as it may harm an unborn baby.
• Breastfeeding mothers: It’s unknown if carvedilol passes into breast milk. Consult with a healthcare provider before breastfeeding.
• Elderly patients: Older adults may be more sensitive to the side effects of carvedilol, particularly dizziness and lightheadedness.
• Children: The safety and effectiveness of carvedilol in children have not been established.

Drug Interactions: Medications to Watch Out For

Carvedilol can interact with various medications, potentially affecting its efficacy or increasing the risk of side effects. What are some common drug interactions to be aware of?

• Other blood pressure medications
• Certain antidepressants
• Drugs used to treat diabetes
• Medications for heart rhythm problems
• NSAIDs (non-steroidal anti-inflammatory drugs)
• Certain antifungal medications

It’s crucial to inform your healthcare provider about all medications you’re taking to avoid potential interactions and ensure safe, effective treatment with carvedilol.

Long-Term Use of Carvedilol: What to Expect

For many patients, carvedilol is a long-term medication used to manage chronic cardiovascular conditions. What should patients know about the extended use of Coreg?

• Regular monitoring: Your doctor will likely schedule regular check-ups to assess your response to the medication and adjust the dosage if necessary.
• Consistent use: It’s important to take carvedilol regularly as prescribed, even if you feel well, to maintain its beneficial effects.
• Gradual discontinuation: If you need to stop taking carvedilol, your doctor will likely recommend a gradual reduction in dosage to avoid potential withdrawal effects.
• Lifestyle modifications: Carvedilol is often most effective when combined with heart-healthy lifestyle changes, such as a balanced diet, regular exercise, and stress management.

Patients should communicate openly with their healthcare providers about any concerns or changes in their condition during long-term carvedilol treatment.

Monitoring Blood Pressure and Heart Rate

Regular monitoring of blood pressure and heart rate is crucial for patients taking carvedilol. This helps ensure that the medication is working effectively and allows for timely adjustments to the treatment plan if needed. Patients may be advised to:

• Keep a log of their blood pressure readings
• Use a home blood pressure monitor as directed by their healthcare provider
• Report any significant changes in blood pressure or heart rate to their doctor

Alternatives to Carvedilol: Exploring Other Treatment Options

While carvedilol is an effective medication for many patients, it may not be suitable for everyone. What are some alternative treatments for cardiovascular conditions?

• Other beta-blockers (e.g., metoprolol, atenolol)
• ACE inhibitors (e.g., lisinopril, enalapril)
• Angiotensin receptor blockers (ARBs) (e.g., losartan, valsartan)
• Calcium channel blockers (e.g., amlodipine, diltiazem)
• Diuretics (e.g., furosemide, hydrochlorothiazide)

The choice of medication depends on various factors, including the specific condition being treated, individual patient characteristics, and potential side effects. Healthcare providers will work with patients to determine the most appropriate treatment plan.

Complementary Therapies and Lifestyle Changes

In addition to medication, various lifestyle modifications and complementary therapies can support cardiovascular health:

• Regular physical activity
• Heart-healthy diet (e.g., Mediterranean diet)
• Stress reduction techniques (e.g., meditation, yoga)
• Smoking cessation
• Limiting alcohol consumption
• Maintaining a healthy weight

These approaches can complement the effects of carvedilol and other medications, contributing to overall cardiovascular well-being.

Coreg Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Uses

Carvedilol is used to treat high blood pressure and heart failure. It is also used after a heart attack to improve the chance of survival if your heart is not pumping well. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.This drug works by blocking the action of certain natural substances in your body, such as epinephrine, on the heart and blood vessels. This effect lowers your heart rate, blood pressure, and strain on your heart. Carvedilol belongs to a class of drugs known as alpha and beta blockers.

How to use Coreg

See also Warning section.

Read the Patient Information Leaflet if available from your pharmacist before you start taking carvedilol and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with food as directed by your doctor, usually twice daily.

The dosage is based on your medical condition and response to treatment. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor’s instructions carefully.

Take this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.

For the treatment of high blood pressure, it may take 1 to 2 weeks before you get the full benefit of this drug. Keep taking this medication even if you feel well. Most people with high blood pressure do not feel sick.

Tell your doctor if your condition does not improve or if it worsens (for example, your blood pressure readings remain high or increase, or you have worsening symptoms of heart failure like increased shortness of breath).

Side Effects

See also Warning and Precautions sections.

Dizziness, lightheadedness, drowsiness, diarrhea, impotence, or tiredness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. The risk of dizziness is highest within 1 hour after you take your dose. Taking this medication with food and starting treatment with a low dose and slowly increasing your dose as directed by your doctor help to reduce the risk of dizziness.

This drug may reduce blood flow to your hands and feet, causing them to feel cold. Smoking may worsen this effect. Dress warmly and avoid tobacco use.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: very slow heartbeat, severe dizziness, fainting, unusual weakness, signs of kidney problems (such as change in the amount of urine), numbness/tingling of the hands/feet, blue fingers/toes, easy bruising/bleeding, mental/mood changes (such as confusion, depression), seizures.

Although this medication may be used to treat heart failure, some people may rarely develop new or worsening symptoms of heart failure, especially at the start of carvedilol treatment. Tell your doctor right away if you develop any of these serious side effects: shortness of breath, swelling ankles/feet, unusual tiredness, unusual/sudden weight gain.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking carvedilol, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: certain types of heartbeat/heart rhythm problems (such as slow/irregular heartbeat, sick sinus syndrome, second- or third-degree atrioventricular block), breathing problems (such as asthma, chronic bronchitis, emphysema), severe heart failure requiring hospitalization, liver disease, kidney disease, blood circulation problems (such as Raynaud’s disease, peripheral vascular disease), serious allergic reactions including those needing treatment with epinephrine, overactive thyroid disease (hyperthyroidism), a certain type of tumor (pheochromocytoma), other heart problems (such as Prinzmetal’s variant angina), a certain muscle disease (myasthenia gravis), certain eye problems (cataracts, glaucoma).

This drug may make you dizzy or drowsy or cause you to faint. This is most likely to occur within 1 hour after taking your dose, especially when you start carvedilol treatment or any time your doctor increases your dose. During these periods, avoid driving and doing hazardous tasks. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).

People who wear contact lenses may have dry eyes while taking this medication.

Before having surgery (including cataract/glaucoma eye surgery), tell your doctor or dentist if you are taking or have ever taken this medication, and about all the other products you use (including prescription drugs, nonprescription drugs, and herbal products).

This product may prevent the fast/pounding heartbeat you would usually feel when your blood sugar level falls too low (hypoglycemia). The risk is higher if you have diabetes, or are vomiting, fasting, or not eating regularly. Other symptoms of low blood sugar level, such as dizziness and sweating, are not affected by this drug.

If you have diabetes, this product may make it harder to control your blood sugar levels. Check your blood sugar levels regularly as directed by your doctor. Tell your doctor right away if you have symptoms of high blood sugar such as increased thirst/urination. Your doctor may need to adjust your diabetes medication, exercise program, or diet.

Children may be at greater risk for low blood sugar (hypoglycemia) while using this drug, especially if they are vomiting or not eating regularly. To help prevent low blood sugar, make sure children eat regularly. If your child cannot eat regularly, is vomiting, or has symptoms of low blood sugar (such as sweating, shaking), tell the doctor right away.

Older adults may be more sensitive to the side effects of this drug, especially dizziness and lightheadedness.

Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while using carvedilol. Carvedilol may harm an unborn baby. If you become pregnant, talk to your doctor right away about the risks and benefits of this medication.

It is unknown if carvedilol passes into breast milk. However, it is unlikely to pass into breast milk in large amounts. There is a low risk that it may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

One product that may interact with this drug is: fingolimod.

Some products have ingredients that could raise your heart rate or blood pressure or worsen your heart failure. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen).

Does Coreg interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: very slow heartbeat, severe dizziness, fainting, slow/shallow breathing, seizures.

Do not share this medication with others.

Lifestyle changes that may help this medication work better include exercising, stopping smoking, and eating a low-cholesterol/low-fat diet. Consult your doctor for more details.

Have your blood pressure and pulse (heart rate) checked regularly while taking this medication. Learn how to monitor your own blood pressure and pulse at home, and share the results with your doctor.

Lab and/or medical tests (such as kidney/liver function) should be done while you are taking this medication. Keep all medical and lab appointments. Consult your doctor for more details.

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Images

Coreg 6.25 mg tablet

Color: whiteShape: ovalImprint: SB 4140 SB 4140

This medicine is a white, oval, film-coated, tablet imprinted with “SB 4140” and “SB 4140”.

Coreg 12.5 mg tablet

Color: whiteShape: ovalImprint: SB 4141 SB 4141

This medicine is a white, oval, film-coated, tablet imprinted with “SB 4140” and “SB 4140”.

Coreg 3.125 mg tablet

Color: whiteShape: ovalImprint: SB 39

This medicine is a white, oval, film-coated, tablet imprinted with “SB 4140” and “SB 4140”.

Coreg 25 mg tablet

Color: whiteShape: ovalImprint: SB 4142 SB 4142

This medicine is a white, oval, film-coated, tablet imprinted with “SB 4140” and “SB 4140”.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

Side effects, dosage, uses, and more

1. Carvedilol oral tablet is available as a generic drug and a brand-name drug. Brand-name: Coreg.
2. Carvedilol also comes as an oral extended-release capsule.
3. Carvedilol is a beta-blocker. It’s used to treat high blood pressure, heart failure, and heart function problems after a heart attack.

• Sudden drug stoppage warning: Don’t stop taking this drug without talking to your doctor first. Stopping carvedilol suddenly can cause changes in your heart rhythm, worsened chest pain, or a heart attack. If you will be stopping this drug, your doctor will slowly lower your dosage over one to two weeks to help prevent these effects. If your chest pain or heart problems get worse after stopping this drug, your doctor may have you start taking it again for a short time.
• Low heart rate warning: Carvedilol can decrease your heart rate. If your heart rate drops below 55 beats per minute, your doctor may decrease your dosage of this drug.
• Low blood pressure warning: Carvedilol can cause dangerously low blood pressure, which may cause you to lose consciousness. This risk is highest after your first doses and during dosing increases. To decrease the risk of this happening, take carvedilol with food. Your doctor may start you on a low dosage and slowly increase it.
• Diabetes warning: Carvedilol can cause low blood sugar levels (hypoglycemia) and delay how long it takes your blood sugar levels to return to normal. It may also mask the signs of low blood sugar levels. Use this drug with caution if you have diabetes, especially if you take insulin or other diabetes drugs that can cause low blood sugar.

Carvedilol oral tablet is a prescription drug that’s available as the brand-name drug Coreg. It’s also available as a generic drug. Generic drugs usually cost less. In some cases, a generic drug may not be available in every strength or form as a brand-name version.

Carvedilol also comes as an extended-release oral capsule.

Why it’s used

Carvedilol oral tablet is used to treat high blood pressure. It can also improve how well your heart works if you’ve had a heart attack or if you have heart failure.

This drug is approved to treat:

• heart failure
• left ventricular dysfunction (a heart function problem) after a heart attack
• high blood pressure

How it works

Carvedilol belongs to a class of drugs called beta-blockers. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

It isn’t fully understood how carvedilol works to treat high blood pressure or improve heart function. However, it is known that carvedilol improves the workload of your heart, exercise-induced high heart rate, and high heart rate upon standing. It also widens your blood vessels, which helps to decrease your blood pressure.

Carvedilol oral tablet can cause several types of side effects, including drowsiness. Don’t drive, use machinery, or perform activities that require alertness until you know how this drug affects you.

More common side effects

The more common side effects that can occur with carvedilol oral tablet include:

• dizziness
• unusual tiredness
• low blood pressure
• diarrhea
• high blood sugar
• lack of energy or weakness
• slower heart rate
• weight gain
• changes in sex drive or performance
• dry eyes
• dry, itchy skin
• headache
• nausea

If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.

Serious side effects

Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

• Allergic reactions. Symptoms can include:
  • skin rash
  • hives
  • swelling of your face, lips, or tongue
• Changes in your heart rate. Symptoms can include:
  • irregular or slow heart rate
  • feeling dizzy or fainting
• Heart problems. Symptoms can include:
  • breathing problems or shortness of breath
  • weight gain
  • swollen legs, ankles, or arms
  • chest pain
• Liver problems. Symptoms can include:
  • dark-colored urine
  • vomiting
  • yellowing of your skin or the whites of your eyes
• Eye problems. Symptoms can include:
  • change in eyesight
  • changes in how contact lenses feel in your eyes
• Urinary problems. Symptoms can include:
  • being unable to pass urine
  • change in how much urine you pass

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.

Carvedilol oral tablet can interact with other medications, herbs, or vitamins you might be taking. That’s why your doctor should manage all of your medications carefully. If you’re curious about how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

Note: You can reduce your chances of drug interactions by having all of your prescriptions filled at the same pharmacy. That way, a pharmacist can check for possible drug interactions.

Examples of drugs that can cause interactions with carvedilol are listed below.

Heart rhythm drugs

Taking certain heart rhythm drugs with carvedilol can cause more severe side effects. The combination may lower your heart rate or blood pressure, or worsen a heart blockage. Your doctor may watch you closely for side effects or adjust the dosage of carvedilol or your heart rhythm drug.

Examples of these drugs include:

• amiodarone
• bretylium
• quinidine
• digoxin
• disopyramide
• encainide
• flecainide
• propafenone
• procainamide
• sotalol

Blood pressure drug

Using clonidine with carvedilol can lower your blood pressure and heart rate even further. If you’re switching to carvedilol from clonidine, your doctor will slowly take you off clonidine. You’ll start carvedilol several days after stopping clonidine. If you need both drugs, your doctor will watch you for low blood pressure and low heart rate. If you’re on both drugs and both need to be stopped, your doctor will stop your treatment with carvedilol first and clonidine a few days later.

Other beta-blockers

Carvedilol shouldn’t be used with another beta-blocker. This combination may lower your heart rate and blood pressure too much. Examples of other beta-blockers include:

• acebutolol
• atenolol
• bisoprolol
• metoprolol
• propranolol

Calcium channel blockers

If you take a calcium channel blocker with carvedilol, your doctor will monitor your blood pressure and heart rhythm. Examples of these drugs include:

• diltiazem
• verapamil

Diabetes drugs

Using carvedilol with certain diabetes drugs can make these diabetes drugs lower your blood sugar levels further. If you take these diabetes drugs with carvedilol, you’ll need to check your blood sugar regularly. Examples of these drugs include:

• insulin
• oral diabetes drugs

Transplant rejection drug

Taking carvedilol with cyclosporine may increase the levels of cyclosporine in your body. Your doctor may lower your dosage of cyclosporine and monitor you closely.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

This drug comes with several warnings.

Allergy warning

Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal. Symptoms of an allergic reaction include:

• rash or hives
• itching
• blistering or peeling skin
• fever
• problems breathing or chest tightness
• swelling of your mouth, face, lips, tongue or throat

If you have a history of severe, life-threatening allergic reactions to different allergens, you’re at a higher risk of having the same reaction to beta-blockers. Tell your doctor about all of your allergies before starting this medication.

Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).

Alcohol interaction warning

Talk to your doctor before using alcohol while taking this medication. If you drink alcohol while taking carvedilol, your blood pressure may decrease to levels that are lower than normal. This can be dangerous.

Warnings for people with certain health conditions

For people with asthma: If you have asthma or a related condition, you shouldn’t use this drug. A single dose of carvedilol can be fatal in people with asthma.

For people with heart problems:

• Second- or third-degree heart block: Carvedilol can make your heart block worse.
• Heart rhythm problems: If you already have a heart rhythm problem, such as sick sinus syndrome, taking carvedilol can make it worse.
• Very low heart rate: This drug can slow down your heart rate even more, possibly to dangerously low levels. Don’t take carvedilol if you have a very low heart rate unless you have a permanent pacemaker.
• Cardiogenic shock or decompensated heart failure: People with shock or decompensated failure that requires the use of certain medications (inotropic therapy that’s administered into your veins) shouldn’t use this drug. It can make the condition worse.
• Chronic heart failure: Carvedilol can worsen heart failure or fluid retention, especially during dosage increases. Carvedilol can further decrease the force of contraction of your heart and slow down your heart rate. This may make your heart failure worse if your dosage is increased too quickly. Your doctor may need to lower your dosage or temporarily stop carvedilol if this happens.

For people with severe liver problems: You shouldn’t take this medication. It’s broken down by your liver. When your liver isn’t working properly, taking this medication can result in higher amounts of it in your body. This may lead to serious side effects, such as dangerously low blood pressure or slow heart rate.

For people with low blood pressure: Carvedilol can cause dangerously low blood pressure that may cause you to lose consciousness.

For people with chronic bronchitis or emphysema: You shouldn’t take carvedilol or other beta-blockers. This drug can affect not only your heart but also your lungs. Its effects in your lungs can lead to tightened airways, making it difficult for you to breathe.

For people with diabetes: Carvedilol can cause low blood sugar (hypoglycemia) and delay how long it takes for your blood sugar to return to normal. It may also mask the signs of low blood sugar. Use this drug with caution if you have diabetes, especially if you take insulin or other diabetes drugs that can cause low blood sugar. If you have diabetes and are taking this medication for heart failure, it may increase your blood sugar levels. You’ll need to monitor your blood sugar and your doctor will adjust your medications accordingly.

For people with peripheral vascular disease (PVD): Use caution if you have PVD and take carvedilol. This drug can make your symptoms worse.

For people with kidney problems: Carvedilol can worsen your kidney function if you have heart failure. You’re at a higher risk if you have low blood pressure or heart or vascular disease. Your doctor will monitor your kidney function and may lower your dosage or stop your treatment with carvedilol.

For people with hyperactive thyroid: Carvedilol can mask the symptoms of a hyperactive thyroid (hyperthyroidism). If you stop taking carvedilol suddenly and have hyperthyroidism, your symptoms can get worse or you may develop a serious condition called thyroid storm

For people with pheochromocytoma: Take this medication with caution if you have this condition. If you have pheochromocytoma, talk with your doctor. You may need to take another medication before starting carvedilol.

For people with Prinzmetal’s variant angina (chest pain that occurs between midnight and the early morning): Carvedilol may increase your risk of chest pain if you have Prinzmetal’s variant angina. Talk with your doctor before taking carvedilol if you have this condition.

For people with intraoperative floppy iris syndrome: Before receiving any type of cataract surgery, tell your doctor that you’re taking this drug. You’re at an increased risk of getting a condition called small pupil syndrome during surgery.

Warnings for other groups

For pregnant women: Carvedilol is a category C pregnancy drug. That means two things:

1. Research in animals has shown adverse effects to the fetus when the mother takes the drug.
2. There haven’t been enough studies done in humans to be certain how the drug might affect the fetus.

Tell your doctor if you’re pregnant or plan to become pregnant. Carvedilol should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

For women who are breastfeeding: It isn’t known if carvedilol passes into breast milk. If it does, it may cause serious effects in a breastfeeding child. You and your doctor may need to decide if you’ll take carvedilol or breastfeed.

For seniors: Seniors may be more likely to experience dizziness while taking this drug.

For children: It has not been established that carvedilol is safe and effective for use in people under the age of 18 years.

This dosage information is for carvedilol oral tablets. All possible dosages and forms may not be included here. Your dose, form, and how often you take it will depend on:

• your age
• the condition being treated
• the severity your condition
• other medical conditions you have
• how you react to the first dose

Forms and strengths

Generic: Carvedilol

• Form: oral tablet
• Strengths: 3. 125 mg, 6.25 mg, 12.5 mg, and 25 mg

Brand: Coreg

• Form: oral tablet
• Strengths: 3.125 mg, 6.25 mg, 12.5 mg, and 25 mg

Dosage for heart function problems following heart attack

Adult dosage (ages 18 years and older)

• The recommended starting dosage is 6.25 mg taken twice per day.
• It can be increased after 3 to 10 days to 12.5 mg taken twice per day.
• It can be increased up to 25 mg taken twice per day.
• You’ll be kept on a lower dosage if you can’t tolerate higher dosages.

Child dosage (ages 0 to 17 years)

A safe and effective dosage hasn’t been established for this age group.

Special considerations

• For people with kidney problems: If you have kidney problems, your doctor will closely monitor you during treatment. They may lower your dose or stop treatment if your kidney function gets worse.
• For people with low blood pressure or heart rate or who are retaining fluid:
  • You may be started at a lower dosage of 3.125 mg taken twice per day. Or, your dosage may be increased at a slower rate.
  • You’ll be kept on a lower dosage if you can’t tolerate higher dosages.

Warnings

Your doctor will monitor you closely during dosage increases.

Dosage for high blood pressure

Adult dosage (ages 18 years and older)

• The recommended starting dose is 6.25 mg taken twice per day.
• It can be increased after 7 to 14 days based on your blood pressure level one hour after your dose.
• Your dosage can be first increased to 12.5 mg taken twice per day. It can be increased again to 25 mg taken twice per day.
• The total dosage shouldn’t go over 50 mg per day.

Child dosage (ages 0 to 17 years)

A safe and effective dosage hasn’t been established for this age group.

Special considerations

• For people with kidney problems: If you have kidney problems, your doctor will closely monitor you during treatment. They may lower your dose or stop treatment if your kidney function gets worse.

Warnings

Your doctor will monitor you closely during dosage increases.

Dosage for heart failure

Adult dosage (ages 18 years and older)

• The recommended starting dosage is 3.125 mg taken twice per day for two weeks.
• It can be increased to 6.25 mg, 12.5 mg, and 25 mg taken twice per day over two-week intervals.
• When you first start the medication and during dosage increases, you might feel dizzy and lightheaded within the first hour of taking your dose. During this time, you shouldn’t drive or do any similar activities that require alertness.

Child dosage (ages 0 to 17 years)

A safe and effective dosage hasn’t been established for this age group.

Special considerations

• For people with kidney problems: If you have kidney problems, your doctor will closely monitor you during treatment. They may lower your dose or stop treatment if your kidney function gets worse.

Warnings

Your doctor will monitor you closely during dosage increases.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always speak with your doctor or pharmacist about dosages that are right for you.

Carvedilol oral tablet is used for long-term treatment. It comes with serious risks if you don’t take it as prescribed.

If you don’t take it at all: Your condition may not improve and it may get worse.

If you skip or miss doses: Your blood pressure or heart condition may not be controlled if you skip or miss doses.

If you take too much: An overdose of this drug could cause your heart to stop. Symptoms of overdose of carvedilol include:

• low blood pressure and heart rate
• vomiting
• loss of consciousness
• seizures
• trouble breathing

If you think you’ve taken too much of this drug, call your doctor or local poison control center. If your symptoms are severe, call 911 or go to the nearest emergency room right away.

What to do if you miss a dose: If you miss a dose, take it as soon as you can. If it’s just a few hours before the time for your next dose, then only take one dose at that time. Never try to catch up by taking two doses at once. This could result in toxic side effects.

How to tell if the drug is working: You may be able to tell this drug is working if your blood pressure decreases or your other symptoms improve.

Keep these considerations in mind if your doctor prescribes carvedilol oral tablet for you.

General

• Take carvedilol with food. Taking it with food reduces your risk of side effects.
• You can crush carvedilol tablets.
• The generic version of this drug is usually stocked at most pharmacies. However, the brand-name version might not be stocked, so call ahead if your doctor prescribes that version.

Storage

• Store in temperatures below 86°F (30°C).
• Don’t store this medication in moist or damp areas, such as bathrooms.

Refills

A prescription for this medication is refillable. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.

Travel

When traveling with your medication:

• Always carry your medication with you. When flying, never put it into a checked bag. Keep it in your carry-on bag.
• Don’t worry about airport X-ray machines. They can’t hurt your medication.
• You may need to show airport staff the pharmacy label for your medication. Always carry the original prescription-labeled box with you.
• Don’t put this medication in your car’s glove compartment or leave it in the car. Be sure to avoid doing this when the weather is very hot or very cold.

Clinical monitoring

During treatment with carvedilol, your doctor may check your:

• blood pressure
• heart rate
• weight
• blood sugar (if you have diabetes)
• liver function
• potassium levels
• cholesterol levels

There are other drugs available to treat your condition. Some may be more suitable for you than others. Talk to your doctor about possible alternatives.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication.