What is Cozaar used for. How does Losartan work to lower blood pressure. What are the potential side effects of taking Cozaar. When should you consult your doctor while using Losartan. How to properly take Cozaar for maximum effectiveness.

Understanding Cozaar: A Comprehensive Guide to Losartan

Cozaar, also known by its generic name Losartan, is a widely prescribed medication used primarily in the treatment of hypertension (high blood pressure). As an angiotensin receptor blocker (ARB), Cozaar plays a crucial role in managing cardiovascular health and reducing the risk of associated complications. This comprehensive guide will delve into the various aspects of Cozaar, including its uses, mechanism of action, proper administration, potential side effects, and important precautions.

The Primary Uses of Cozaar in Medical Treatment

Cozaar serves multiple purposes in the medical field, addressing various cardiovascular and renal concerns. Its primary applications include:

• Treatment of hypertension (high blood pressure)
• Protection of kidneys from diabetes-related damage
• Reduction of stroke risk in patients with hypertension and enlarged hearts
• Prevention of heart attacks and kidney problems associated with high blood pressure

By effectively managing these conditions, Cozaar contributes significantly to overall cardiovascular health and well-being.

How does Cozaar work to address these medical conditions?

Cozaar belongs to a class of medications known as angiotensin receptor blockers (ARBs). Its mechanism of action involves relaxing blood vessels, which facilitates easier blood flow throughout the body. This relaxation effect helps lower blood pressure and reduces the workload on the heart, ultimately contributing to better cardiovascular health.

Proper Administration and Dosage of Cozaar

To ensure maximum effectiveness and minimize potential side effects, it’s crucial to administer Cozaar correctly. Here are some key points to remember:

1. Read the Patient Information Leaflet provided by your pharmacist before starting treatment.
2. Take Cozaar orally, with or without food, as directed by your healthcare provider.
3. The typical dosage is once daily, but this may vary based on individual medical conditions and treatment responses.
4. If using the liquid form, shake the bottle well and use a special measuring device to ensure accurate dosing.
5. Maintain a consistent schedule, taking the medication at the same time each day.
6. Continue the medication regimen even if you feel well, as hypertension often has no noticeable symptoms.

Can the dosage of Cozaar be adjusted?

Yes, the dosage of Cozaar can be adjusted. Your healthcare provider may modify your dosage based on your medical condition and how you respond to the treatment. It’s important to follow your doctor’s instructions closely and not adjust the dosage on your own.

Potential Side Effects and Adverse Reactions to Cozaar

While Cozaar is generally well-tolerated, like all medications, it can cause side effects in some individuals. Common side effects may include:

• Dizziness or lightheadedness
• Fatigue
• Headache
• Nasal congestion
• Diarrhea

More serious side effects, although rare, can occur. These may include:

• Fainting
• Symptoms of high potassium levels (muscle weakness, slow/irregular heartbeat)
• Changes in kidney function
• Severe allergic reactions (rash, itching/swelling, severe dizziness, trouble breathing)

How should one respond to side effects from Cozaar?

If you experience persistent or worsening side effects, it’s important to contact your healthcare provider promptly. For mild side effects, such as dizziness, rising slowly from a sitting or lying position may help. In case of severe allergic reactions or signs of serious side effects, seek immediate medical attention.

Important Precautions and Contraindications for Cozaar Use

Before starting treatment with Cozaar, it’s crucial to consider certain precautions and potential contraindications:

• Pregnancy: Cozaar can cause serious harm to an unborn baby. Use reliable birth control and inform your doctor immediately if you become pregnant or plan to become pregnant.
• Allergies: Inform your healthcare provider about any allergies, especially to ARBs or ACE inhibitors.
• Medical history: Disclose your complete medical history, particularly regarding liver disease, dehydration, or high potassium levels.
• Drug interactions: Cozaar may interact with other medications, including potassium supplements and certain pain relievers.
• Alcohol and marijuana use: These substances may increase dizziness when combined with Cozaar.

Are there specific conditions that preclude the use of Cozaar?

Yes, certain conditions may contraindicate the use of Cozaar. These include pregnancy, severe liver disease, and a history of angioedema related to previous ARB use. Your healthcare provider will assess your individual case to determine if Cozaar is appropriate for you.

Monitoring and Follow-up Care While Taking Cozaar

Regular monitoring is essential when using Cozaar to ensure its effectiveness and detect any potential issues early. This typically involves:

1. Regular blood pressure checks
2. Periodic blood tests to monitor kidney function and potassium levels
3. Reporting any new or worsening symptoms to your healthcare provider
4. Attending scheduled follow-up appointments
5. Maintaining open communication with your healthcare team about your treatment progress

How often should blood pressure be monitored while on Cozaar?

The frequency of blood pressure monitoring may vary depending on individual circumstances. Initially, more frequent checks may be necessary. As your blood pressure stabilizes, your healthcare provider may recommend less frequent monitoring. Home blood pressure monitoring can be a useful tool in tracking your progress between clinic visits.

Cozaar and Lifestyle Modifications for Optimal Blood Pressure Management

While Cozaar is an effective medication for managing hypertension, combining it with lifestyle modifications can enhance its benefits. Consider incorporating the following strategies:

• Adopting a heart-healthy diet rich in fruits, vegetables, and whole grains
• Reducing sodium intake
• Engaging in regular physical activity as approved by your healthcare provider
• Maintaining a healthy weight
• Limiting alcohol consumption
• Quitting smoking
• Managing stress through relaxation techniques or counseling

How do lifestyle changes complement the effects of Cozaar?

Lifestyle modifications work synergistically with Cozaar to improve overall cardiovascular health. These changes can help lower blood pressure naturally, potentially allowing for lower medication doses and reducing the risk of side effects. Additionally, a healthy lifestyle contributes to better overall health outcomes beyond blood pressure control.

Potential Drug Interactions and Considerations with Cozaar

Cozaar can interact with various medications and substances, potentially affecting its efficacy or increasing the risk of side effects. Some notable interactions include:

• Other blood pressure medications
• Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen
• Potassium supplements or salt substitutes containing potassium
• Lithium
• Certain diuretics

It’s crucial to inform your healthcare provider about all medications, supplements, and herbal products you are taking to avoid potential interactions.

How can patients minimize the risk of drug interactions with Cozaar?

To minimize the risk of drug interactions, patients should:

1. Maintain an up-to-date list of all medications and supplements
2. Inform all healthcare providers about Cozaar use
3. Avoid starting new medications or supplements without consulting a healthcare provider
4. Be cautious with over-the-counter medications, particularly pain relievers and cold remedies
5. Follow dietary recommendations, especially regarding potassium intake

Long-term Considerations and Outcomes of Cozaar Treatment

Long-term use of Cozaar can provide significant benefits in managing hypertension and reducing the risk of associated complications. However, it’s important to consider the following aspects of long-term treatment:

• Regular monitoring of blood pressure and kidney function
• Potential need for dosage adjustments over time
• Ongoing assessment of treatment efficacy and side effects
• Consideration of combination therapy if blood pressure goals are not met with Cozaar alone
• Continuous evaluation of overall cardiovascular risk factors

What are the potential long-term benefits of consistent Cozaar use?

Consistent long-term use of Cozaar, when combined with appropriate lifestyle modifications, can lead to several positive outcomes:

• Sustained blood pressure control
• Reduced risk of heart attacks and strokes
• Protection against kidney damage, particularly in diabetic patients
• Improved overall cardiovascular health
• Potential reduction in the progression of heart failure in certain patients

As with any long-term medication regimen, it’s essential to maintain open communication with your healthcare provider and attend regular check-ups to ensure optimal management of your condition.

Special Considerations for Specific Patient Populations

While Cozaar is widely used, certain patient populations may require special considerations or modifications in their treatment approach:

Elderly Patients

Older adults may be more sensitive to the effects of Cozaar and may require lower initial doses. Careful monitoring of kidney function and blood pressure is crucial in this population.

Patients with Kidney Impairment

Cozaar is often used to protect kidney function, but in patients with existing kidney impairment, dosage adjustments may be necessary. Regular monitoring of kidney function is essential.

Diabetic Patients

Cozaar can be particularly beneficial for diabetic patients with hypertension, as it may help protect against kidney damage. However, close monitoring of blood sugar levels is important, as Cozaar can affect glucose metabolism.

Patients with Liver Disease

In patients with liver impairment, Cozaar may need to be used with caution. Lower doses may be recommended, and liver function should be closely monitored.

How should healthcare providers approach Cozaar treatment in these special populations?

Healthcare providers should take a personalized approach when prescribing Cozaar to special populations:

1. Conduct a thorough assessment of the patient’s overall health status
2. Consider starting with lower doses and titrating slowly
3. Implement more frequent monitoring of blood pressure, kidney function, and relevant laboratory parameters
4. Be vigilant for potential side effects or complications
5. Adjust treatment plans as needed based on individual patient responses and tolerability

Comparing Cozaar with Other Antihypertensive Medications

Cozaar belongs to the angiotensin receptor blocker (ARB) class of medications, but it’s not the only option for treating hypertension. Understanding how Cozaar compares to other antihypertensive drugs can help patients and healthcare providers make informed decisions about treatment options.

Cozaar vs. ACE Inhibitors

ACE inhibitors, like lisinopril or enalapril, work similarly to ARBs but target a different part of the renin-angiotensin system. While both classes are effective, ARBs like Cozaar tend to have fewer side effects, particularly the dry cough associated with ACE inhibitors.

Cozaar vs. Calcium Channel Blockers

Calcium channel blockers, such as amlodipine, work by a different mechanism to lower blood pressure. They may be preferred in certain populations, like older adults or those with certain heart conditions. Cozaar may be advantageous in patients with diabetes or kidney disease.

Cozaar vs. Diuretics

Diuretics, like hydrochlorothiazide, lower blood pressure by reducing fluid volume in the body. They are often used as first-line treatments or in combination with ARBs like Cozaar for enhanced effect.

What factors influence the choice between Cozaar and other antihypertensive medications?

Several factors can influence the choice of antihypertensive medication:

• Individual patient characteristics (age, race, comorbidities)
• Presence of target organ damage (e.g., kidney disease, heart failure)
• Potential side effects and tolerability
• Cost and insurance coverage
• Presence of contraindications to specific drug classes
• Patient preferences and lifestyle considerations

Ultimately, the choice of antihypertensive medication should be a collaborative decision between the patient and healthcare provider, taking into account all relevant factors to ensure the most effective and well-tolerated treatment approach.

Cozaar Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Warnings:

This drug can cause serious (possibly fatal) harm to an unborn baby if used during pregnancy. It is important to prevent pregnancy while taking this medication. Consult your doctor for more details and to discuss the use of reliable forms of birth control while taking this medication. If you are planning pregnancy, become pregnant, or think you may be pregnant, contact your doctor right away.

Warnings:

This drug can cause serious (possibly fatal) harm to an unborn baby if used during pregnancy. It is important to prevent pregnancy while taking this medication. Consult your doctor for more details and to discuss the use of reliable forms of birth control while taking this medication. If you are planning pregnancy, become pregnant, or think you may be pregnant, contact your doctor right away.

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Uses

Losartan is used to treat high blood pressure (hypertension) and to help protect the kidneys from damage due to diabetes. It is also used to lower the risk of strokes in patients with high blood pressure and an enlarged heart. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Losartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). It works by relaxing blood vessels so that blood can flow more easily.

How to use Cozaar

Read the Patient Information Leaflet if available from your pharmacist before you start taking losartan and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, usually once daily. The dosage is based on your medical condition and response to treatment.

If you are using the liquid form of this medication, shake the bottle well before each dose. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Keep taking this medication even if you feel well. Most people with high blood pressure do not feel sick.

Tell your doctor if your condition does not improve or if it worsens (for example, your blood pressure readings increase).

Side Effects

Dizziness or lightheadedness may occur as your body adjusts to the medication. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: fainting, symptoms of a high potassium blood level (such as muscle weakness, slow/irregular heartbeat).

Although losartan may be used to prevent kidney problems or treat people who have kidney problems, it may also rarely cause serious kidney problems or make them worse. Your doctor will check your kidney function while you are taking losartan. Tell your doctor right away if you have any signs of kidney problems such as a change in the amount of urine.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking losartan, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, dehydration, high level of potassium in the blood.

This drug may make you dizzy. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).

This medication may increase your potassium levels. Before using potassium supplements or salt substitutes that contain potassium, consult your doctor or pharmacist.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while using losartan. Losartan may harm an unborn baby. If you become pregnant, talk to your doctor right away about the risks and benefits of this medication. (See also Warning section.)

It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

Interactions

See also Precautions section.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

Some products that may interact with this drug include: aliskiren, lithium, drugs that may increase the level of potassium in the blood (such as sparsentan, ACE inhibitors including benazepril/lisinopril, birth control pills containing drospirenone).

Some products have ingredients that could raise your blood pressure or worsen your heart failure. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen).

Does Cozaar interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe dizziness, fainting.

Do not share this medication with others.

Lifestyle changes such as stress reduction programs, exercise, and dietary changes may increase the effectiveness of this medicine. Talk to your doctor or pharmacist about lifestyle changes that might benefit you.

Lab and/or medical tests (such as kidney function, potassium levels) should be done while you are taking this medication. Keep all medical and lab appointments. Consult your doctor for more details.

Check your blood pressure regularly while taking this medication. Learn how to monitor your own blood pressure, and share the results with your doctor.

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Store tablets at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Store the suspension in the refrigerator. Do not freeze. Discard any unused suspension after 4 weeks.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Images

Cozaar 100 mg tablet

Color: whiteShape: teardropImprint: 960

This medicine is a white, teardrop, film-coated, tablet imprinted with “960”.

Cozaar 50 mg tablet

Color: whiteShape: ovalImprint: 952

This medicine is a white, teardrop, film-coated, tablet imprinted with “960”.

Cozaar 100 mg tablet

Color: dark greenShape: teardropImprint: 960 MRK

This medicine is a white, teardrop, film-coated, tablet imprinted with “960”.

Cozaar 25 mg tablet

Color: whiteShape: ovalImprint: 951

This medicine is a white, teardrop, film-coated, tablet imprinted with “960”.

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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Cozaar (Losartan potassium) Drug / Medicine Information

NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia.

Losartan potassium

Consumer Medicine Information

What is in this leaflet

This leaflet answers some common questions about COZAAR. It does not contain all
the available information. It does not take the place of talking to your doctor or
pharmacist.

All medicines have risks and benefits. Your doctor has weighed the risks of you taking
COZAAR against the benefits they expect it will have for you.

If you have any concerns about taking this medicine, ask your doctor or pharmacist.

Keep this leaflet with the medicine.

You may need to read it again.

What COZAAR is used for

COZAAR lowers high blood pressure, which doctors call hypertension.

COZAAR is also used to slow the progression of kidney disease in people who have type
2 diabetes mellitus (also known as non-insulin dependent diabetes) with protein in
their urine (which doctors call proteinuria).

Hypertension:

Everyone has blood pressure. This pressure helps get your blood all around your body.
Your blood pressure may be different at different times of the day, depending on how
busy or worried you are. You have hypertension (high blood pressure) when your blood
pressure stays high, even when you are calm and relaxed.

There are usually no symptoms of hypertension. The only way of knowing that you have
hypertension is to have your blood pressure checked on a regular basis. If high blood
pressure is not treated it can lead to serious health problems. You may feel fine
and have no symptoms, but eventually hypertension can cause stroke, heart disease
or kidney failure. COZAAR helps to lower your blood pressure.

Type 2 Diabetes Mellitus:

Type 2 diabetes mellitus is a condition in which the body’s cells do not respond to
the effects of insulin or too little insulin is produced, resulting in an elevated
blood (sugar) level, known as hyperglycaemia.

Insulin maintains the appropriate level of glucose in the blood by transporting it
into the body’s cells so that they can produce energy or store glucose until it’s
needed.

Hyperglycaemia can lead to serious problems with your heart, eyes, circulation or
kidneys. When kidney damage occurs, its ability to filter blood is reduced, and proteins
in the blood are lost in the urine. This may eventually lead to kidney failure.
In people who have type 2 diabetes mellitus with protein in their urine, COZAAR helps
to slow the worsening of kidney disease and reduce the need for dialysis or kidney
transplantation.

How it works

COZAAR belongs to a group of medicines, called angiotensin II receptor antagonists.
It works to lower your blood pressure by relaxing your blood vessels. In addition,
COZAAR slows the progression of kidney disease in people who have type 2 diabetes
mellitus with protein in the urine.

COZAAR is not addictive.

Before you take COZAAR

When you must not take it

Do not take COZAAR if:

you are pregnant or breast-feeding

The use of COZAAR while you are pregnant or breast-feeding is not recommended. Your
baby may absorb this medicine in the womb. COZAAR can cause harm or death to an unborn
baby. Talk to your doctor about other ways to lower your blood pressure if you plan
to become pregnant. If you get pregnant while taking COZAAR tell your doctor right
away. It is not known whether COZAAR passes into breast milk, therefore it is not
recommended to be taken while you are breast-feeding.

you have an allergy to COZAAR or any of the ingredients listed at the end of this
leaflet

you have diabetes and are taking a medicine called aliskiren to reduce blood pressure.

the packaging is torn or shows signs of tampering

the expiry date on the pack has passed.

If you take this medicine after the expiry date has passed, it may not work.

If you are not sure whether you should start taking COZAAR, talk to your doctor.

Do not give COZAAR to a child.

There is no experience with the use of COZAAR in children.

Before you start to take it

Tell your doctor if:

1. you intend to become pregnant or plan to breast-feed

COZAAR should not be used during pregnancy or while breast-feeding.

2. you are taking other medicines that may increase serum potassium (see Taking other
medicines).

3. you have any medical conditions, especially the following:

kidney disease

liver problems or have had these in the past.

4. you have recently had excessive vomiting or diarrhoea

5. you have any allergies to any other medicines or any other substances, such as foods,
preservatives or dyes.

If you have not told your doctor about any of the above, tell them before you take
any COZAAR.

Taking other medicines

Tell your doctor if you are taking any other medicines, including medicines that you
buy without a prescription from your pharmacy, supermarket or health food shop.

Some medicines or substances and COZAAR may interfere with each other. These include:

Other blood pressure medicines

diuretic tablets, also called fluid or water tablets, including potassium-sparing
diuretics

potassium tablets

potassium-containing salt substitutes

other medicines that may increase serum potassium (e.g., trimethoprim-containing products).

medicines used to relieve pain, swelling, and other symptoms of inflammation, for
example, indomethacin.

lithium (a medicine used to treat mood swings and some types of depressions)

grapefruit juice (which should be avoided while taking COZAAR)

These medicines may have an additive effect with COZAAR in lowering your blood pressure,
or may affect how well it works, or may lead to increases in potassium in your blood.
You may need to take different amounts of your medicine, or you may need to take different
medicines.

Your doctor or pharmacist has more information on medicines to be careful with or
avoid while taking COZAAR.

How to take COZAAR

How much to take

Your doctor will tell you how many tablets you need to take each day. This depends
on your condition and whether you are taking other medicines. Take COZAAR only when
prescribed by your doctor.

For high blood pressure:

For most patients, the usual starting dose is one 50 mg tablet taken once a day.
Some patients may need a lower starting dose. The dose may need to be increased depending
on your blood pressure. Most patients take between 25 to 100 mg each day, taken as
a single dose or in divided doses.

For type 2 diabetes mellitus with protein in the urine:

The usual starting dose is one 50 mg tablet taken once a day. The dose may be increased
to 100 mg once a day depending on your blood pressure.

Follow all directions given to you by your doctor carefully. They may differ from
the information contained in this leaflet.

If you do not understand the instructions on the box, ask your doctor or pharmacist
for help.

When to take it

Take your COZAAR at about the same time each day.

Taking your tablet(s) at the same time each day will have the best effect. It will
also help you remember when to take the tablets.

Swallow COZAAR with a glass of water.

It does not matter whether you take COZAAR before or after food.

How long to take it

COZAAR helps control your high blood pressure, but does not cure it. Therefore COZAAR
must be taken every day. Continue taking COZAAR for as long as your doctor prescribes.

If you forget to take it

If it is almost time for your next dose, skip the dose you missed and take your next
dose when you are meant to. Otherwise, take it as soon as you remember, and then
go back to taking your tablet(s) as you would normally.

If you are not sure whether to skip the dose, talk to your doctor or pharmacist.

Do not take a double dose to make up for the dose that you missed.

If you have trouble remembering to take your tablets, ask your pharmacist for some
hints.

If you take too much (overdose)

Immediately telephone your doctor or Poisons Information Centre (telephone 13 11 26),
or go to accident and emergency at your nearest hospital, if you think that you or
anyone else may have taken too much COZAAR. Do this even if there are no signs of
discomfort or poisoning.

If you take too many tablets, you will probably feel light-headed or dizzy.

While you are using COZAAR

Things you must do

If you become pregnant while taking COZAAR, tell your doctor immediately.

Your doctor needs to know immediately so that COZAAR can be replaced by another medicine.

Have your blood pressure checked when your doctor says, to make sure COZAAR is working.

If you are about to be started on any new medicine, tell your doctor and pharmacist
that you are taking COZAAR.

If you feel light-headed, dizzy or faint, get up slowly when getting out of bed or
standing up.

You may feel light-headed or dizzy while taking COZAAR, especially if you are also
taking a diuretic (fluid tablet). This may become worse if you stand up quickly as
your blood pressure may fall. Standing up slowly, especially when you get up from
bed or chairs, will help your body get used to the change in position and blood pressure.
This problem is not common. If it occurs and gets worse or continues, talk to your
doctor.

If you plan to have surgery (even at the dentist) that needs a general anaesthetic,
tell your doctor or dentist that you are taking COZAAR.

Make sure you drink enough water during exercise and hot weather when you are taking
COZAAR, especially if you sweat a lot.

If you do not drink enough water while taking COZAAR, you may faint or feel light-headed
or sick. This is because your body doesn’t have enough fluid and your blood pressure
is low. If you continue to feel unwell, tell your doctor.

If you have excessive vomiting and/or diarrhoea while taking COZAAR, tell your doctor.

This can also mean that you are losing too much water and your blood pressure may
become too low.

If your doctor has prescribed potassium tablets for you, continue taking them.

COZAAR contains a very small amount of potassium, but this does not replace any potassium
tablets that you may be taking.

Go to your doctor regularly for a check-up.

Your doctor may occasionally do a blood test to check your potassium level in the
blood and to see how your kidneys are working.

Things you must not do

Do not give COZAAR to anyone else, even if they have the same condition as you.

Things to be careful of

Be careful driving or operating machinery until you know how COZAAR affects you.

As with many other medicines used to treat high blood pressure, COZAAR may cause dizziness
or light-headedness in some people. Make sure you know how you react to COZAAR before
you drive a car, operate machinery, or do anything else that could be dangerous if
you are dizzy or light-headed. If you drink alcohol, dizziness or light-headedness
may be worse.

Things that would be helpful for your blood pressure

Some self-help measures suggested below may help your condition. Talk to your doctor
or pharmacist about these measures and for more information.

Alcohol –

your doctor may advise you to limit your alcohol intake.

Diet –

eat a healthy diet which includes plenty of fresh vegetables, fruit, bread, cereals
and fish. Also eat less fat and sugar.

Exercise –

regular exercise helps to reduce blood pressure and helps the heart get fitter, but
it is important not to overdo it. Walking is good exercise, but try to find a route
that is fairly flat. Before starting any exercise, ask your doctor about the best
kind of programme for you.

Salt –

your doctor may advise you to watch the amount of salt in your diet. To reduce your
salt intake you should avoid using salt in cooking or at the table.

Smoking –

your doctor may advise you to stop smoking or at least cut down.

Weight –

your doctor may suggest losing some weight to help lower your blood pressure and help
lessen the amount of work your heart has to do. Some people may need a dietician’s
help to lose weight.

Side Effects

Tell your doctor or pharmacist as soon as possible if you do not feel well while you
are taking COZAAR.

COZAAR helps most people with high blood pressure, but it may have unwanted side effects
in a few people. All medicines can have side effects. Sometimes they are serious,
most of the time they are not. You may need medical treatment if you get some of
the side effects.

Ask your doctor or pharmacist to answer any questions you may have.

Tell your doctor if you notice any of the following and they worry you:

dizziness

lightheadedness

tiredness or weakness

spinning sensation

generally feeling unwell

increased sensitivity of the skin to sun

inability to get or maintain an erection

These are the common side effects of COZAAR. For the most part these have been mild.

Also, tell your doctor if you develop cough.

Tell your doctor immediately if you notice any of the following:

skin rash, itchiness

aching muscles, not caused by exercise

signs of anaemia, such as tiredness, being short of breath, and looking pale

bleeding or bruising more easily than normal

These may be serious side effects. Skin rash and itchiness may be symptoms of an
allergic reaction. You may need medical attention. These side effects are not common.

If any of the following happen, stop taking COZAAR and tell your doctor immediately
or go to accident and emergency at your nearest hospital:

swelling of the face, lips, mouth, tongue or throat which may cause difficulty in
swallowing or breathing

severe and sudden onset of pinkish, itchy swellings on the skin, also called hives
or nettlerash

These are serious side effects. If you have them, you may have had a serious allergic
reaction to COZAAR. You may need urgent medical attention or hospitalisation. These
side effects are rare.

Other side effects not listed above may also occur in some patients. Tell your doctor
if you notice any other effects.

Do not be alarmed by this list of possible side effects. You may not experience any
of them.

After using COZAAR

Storage

Keep your tablets in the blister pack until it is time to take them.

If you take the tablets out the blister pack they may not keep well.

Keep it in a cool dry place where the temperature stays below 30°C. Do not store it
or any other medicine in the bathroom or near a sink.

Do not leave it in the car or on window sills.

Heat and dampness can destroy some medicines.

Keep it where children cannot reach it.

A locked cupboard at least one-and-a-half metres above the ground is a good place
to store medicines.

Disposal

If your doctor tells you to stop taking COZAAR or the tablets have passed their expiry
date, ask your pharmacist what to do with any that are left over. 

Product description

What it looks like

COZAAR comes in one type of tablet:

COZAAR 50 mg – white, oval shaped tablet with “952” marked on one side and scored
on the other side.

A pack of COZAAR contains 30 tablets.

Ingredients

Active ingredient:

COZAAR 50 mg – losartan potassium 50 mg per tablet

Inactive ingredients:

microcrystalline cellulose

lactose monohydrate

pregelatinised maize starch

magnesium stearate

hyprolose

hypromellose

titanium dioxide

carnauba wax

COZAAR does not contain gluten, sucrose, tartrazine or any other azo dyes.

Supplier

COZAAR is supplied in Australia by:

Organon Pharma Pty Limited

Building A, 26 Talavera Road,

Macquarie Park, NSW 2113 Australia

This leaflet was prepared in April 2022.

Australian Register Number:

50 mg – AUST R 54809

© 2021 Organon group of companies. All rights reserved.

S-WPPI-OG0954-T-102021

RCN 100000561-AU

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Life and death for two | Evening Dnieper

Rubric: PUBLICATIONS > SOCIETY.
09/13/2017.

Raisa Kozar took care of Svetlana Lashchenko

Svetlana Nikolaevna Lashchenko neatly folded two identical men’s shirts and put them in the closet, on the top shelf. She always dressed her twin sons the same way. And this will be a gift … Then the woman went to the kitchen to drink a daily dose of medicine. When her Maxim and Artem return from the ATO, at first she will not tell anything. Not about how cancer was discovered, nor how she tormented and cried, waiting for news. She promised herself that she would beat the disease by the time they returned.
There are photos of brothers on the kitchen wall: children, graduation, ATO. And next to the icon. Svetlana Nikolaevna thought that she should light a candle. In memory of those two guys – someone’s sons, whom she buried. The flame seemed to stop time. All memories suddenly jumbled up.

Handsome men, activists, heroes
Maxim and Artem Lashchenko are twin brothers, like from movies: who are always together, who are confused, who drive on the same driver’s license. Beautiful, courageous, funny, kind. They even wanted to get married on the same day. Therefore, Maxim was in no hurry to sign with his Anechka, although he considered his wife, and they had a daughter. Waiting for my brother to find a bride.
– These merry fellows constantly played pranks on me, says the aunt of the brothers Raisa Kozar. – But when I accidentally saw them in a photo on a social network, in military uniform, I realized that this was not a joke.
“Hey, where are you? Tell the truth, I know everything … ”, – Raisa Stepanovna Artem put the question point-blank in one of the telephone conversations.
“Yes, aunt, we are at war. But just please, so that mom doesn’t know. She can’t be worried. Don’t worry. Everything is fine, ”Artem reassured.
– Svetlana Nikolaevna did not know anything for another six months. Then she cried and calmed down. The decision of the sons is a sacred thing, – continues Raisa Kozar. “Meanwhile, the twins were sending us funny videos, telling funny stories, as if there had never been a war.

“Hello aunt, my brother and I and the whole battalion wish you a happy birthday. You are the best and most beloved aunt of Paradise on earth, ”Artem’s mischievous voice sounded in the phone on July 25, 2014.
– My next memory is dated August 5, – continues Raisa Kozar. – Svetlana Nikolaevna ran to me at work with teary eyes and, having gathered her last strength, she said: “My boys died.”
– Stop! Who told you? This cannot be, – Raisa Stepanovna hugged her relative.

A moment of silence
Artem and Maxim Lashchenko, together with other fighters, were moving towards Shakhtyorsk in an armored personnel carrier. The smell of smoke, soldier’s humor and adrenaline in the blood – instead of being near their relatives at home, the guys were following orders. Everyone understood that this could be a one-way trip.

This is what was left of the combat vehicle in which the brothers were riding after a shell hit

Media wrote about the explosion of an armored personnel carrier from a direct hit by an enemy shell near the village of Orlovo-Ivanovka. The relatives of the victims were also informed. Svetlana Nikolaevna also received such a call.
– Well, how can you trust someone there, on the other end of the line, – says Raisa Stepanovna. – At first we believed in the best. But then the information was confirmed – they brought two alerts.
Maxim’s body was immediately handed over. But Artyom could not be found in any way.
– We wanted to bury the brothers together, and having dug two graves, we waited for a whole week, – says Raisa Kozar. – And then they said that Artem was missing.
Svetlana Nikolaevna all this time was like in a dream – pills, injections … And suddenly a cemetery, a bunch of young crying people. A closed coffin, a sea of ​​flowers and a moment of silence.
Waking up in the morning, she went out to the balcony. Everything was as before – people hurried to work, poplar leaves rustled in a light breeze, pigeons competed for a place on the ledge. The sun’s rays touched her face, and she smelled the passing summer and loneliness. .. At that moment, more than anything else, I wanted to believe that she was only seeing a terrible dream.

If you dream, then you are alive
– The more time passed, the more we believed that Artem was alive, – says Raisa Kozar. – I took over the investigation, as the mother of the boys was not able to. Gathering information, one day I found out that some guy was in captivity. Having made a bunch of calls, I found the right person and sent him a photo of Artem. I have confirmed the resemblance.
Upon learning this news, Svetlana Nikolaevna simply beamed. She knows for sure that her twins are somewhere among the living. After all, it is not in vain that dreams are dreamed, fortune-tellers and psychics will not deceive. And a mother’s heart never lies. They just can’t express themselves yet.

Maxim Lashchenko has a charming daughter Elina

– Then it turned out that this is not Artem. And people from the front line asked me not to call again, – says Larisa Stepanovna. “A year has already passed since the incident. And I went to the SBU – the last resort. There literally in 3 hours the case was solved. Artem has been found.
The road to Kharkov seemed like an eternity. Raisa Stepanovna didn’t care that her face was swollen with tears. All that was spinning in my head was the name “Artem”. She saw him in front of her: first as a little boy, then as a young man, and then as a happy young man with a charming daughter in his arms. She counted the minutes.
– The bag with Artyom’s body was in the Kharkov morgue for a year. We could not find our boy, because the remains were signed with a different surname, the aunt of the fighters continues. “I recognized him right away. And then the DNA test confirmed the fact.
The mothers said that there is another body that needs to be buried. She tried to understand it. But there are things on earth that are impossible to believe, despite the logic. And there are those in which you firmly believe, no matter what. Maybe that’s why sometimes we can see monuments without names and photos.
“The paratroopers of the 25th airborne brigade are buried here” – this is the inscription on the tombstone of Artyom and Maxim Lashchenko. For their mother, they are alive. Heroes don’t die!

Svetlana Lashchenko raised her sons alone.

Svetlana Nikolaevna felt bad before. And after the funeral, she became even worse: high fever and sugar – she had to go to the hospital. Doctors could not understand for a long time what was the matter, and then they diagnosed an oncological disease. Surgery, chemotherapy, radiation.
She is not afraid of death. Afraid that he won’t be able to see his sons again. “I need to recover in order to look for children,” Svetlana Nikolaevna repeats every day.
– I’m not trying to convince her. It is impossible otherwise, – says Raisa Kozar. – I understood one simple thing: if your loved one cannot come to terms with the loss, come to terms with his decision.
There are photos of brothers on the kitchen wall: children, graduation, ATO. Svetlana Nikolaevna loves to look at them so much. These pictures are a treasure, a part of the soul, they have so much life, I want to talk to them:
“Son, my love… I hear your laughter, I see your amazing smiles. You so often come to me in my dreams. Kiss, hug. And there is no strength, because tears are like stars.
Our information:
Paratroopers of the 25th Airborne Brigade, twin brothers Artem and Maxim Lashchenko, were posthumously awarded the Order For Courage, III degree, and the Order of Bogdan Khmelnitsky. Today their mother Svetlana Nikolaevna Lashchenko (1962 years of birth), who gave the most valuable thing to the country, needs urgent treatment. A woman fights a deadly disease alone. And there is more than one course of chemotherapy ahead. Every day plays a significant role, every penny counts. Only you and I can help her overcome this terrible disease.
PrivatBank card number 5168 7554 0338 1243, Recipient: Raisa Stepanovna Kozar.