Dicloxacillin Brand Names: A Comprehensive Guide to Combination Medications
What are the common brand names for Dicloxacillin combination medications. How many brands are currently available in the market. What are the different forms and dosages of Dicloxacillin combinations. Which pharmaceutical companies manufacture Dicloxacillin brand name products.
Understanding Dicloxacillin and Its Combination Medications
Dicloxacillin is a widely used antibiotic that belongs to the penicillin class of drugs. It’s often combined with other antibiotics to create more potent medications for treating various bacterial infections. This article explores the numerous brand names under which Dicloxacillin combinations are marketed, their manufacturers, and the different forms in which they’re available.
What is Dicloxacillin?
Dicloxacillin is a narrow-spectrum antibiotic primarily used to treat infections caused by penicillinase-producing staphylococci. It’s particularly effective against gram-positive bacteria and is commonly prescribed for skin and soft tissue infections.
Why are Dicloxacillin combinations used?
Combining Dicloxacillin with other antibiotics like Amoxicillin or Ampicillin can broaden the spectrum of bacterial coverage, making the medication effective against a wider range of pathogens. This combination approach can be particularly useful in treating complex infections or when the causative organism is unknown.
Overview of Dicloxacillin Brand Names in the Market
According to the data provided, there are currently 62 brand names for Dicloxacillin combination medications available in the market. These brands are produced by various pharmaceutical companies and come in different forms and dosages.
How many Dicloxacillin combination brands are available?
The drug directory on Medindia lists 62 brands that market generic versions of Dicloxacillin combinations under various brand names. This extensive list offers healthcare providers and patients a wide range of options when it comes to choosing a suitable medication.
What forms do Dicloxacillin combinations come in?
Dicloxacillin combinations are available in various forms to suit different patient needs and treatment requirements. These include:
- Tablets
- Capsules
- Syrups
- Creams
- Gels
- Ointments
- Liquids
- Injections
The diversity in formulations allows for flexibility in administration, catering to different age groups and specific medical conditions.
Popular Dicloxacillin Combination Brand Names
Let’s explore some of the popular brand names under which Dicloxacillin combinations are marketed:
1. Abcloxx
Manufactured by Centaur Pharmaceuticals Pvt Ltd, Abcloxx combines Amoxycillin (250mg) with Dicloxacillin (250mg). This combination provides broad-spectrum antibiotic coverage, making it effective against a wide range of bacterial infections.
2. ADC (250mg/250mg)
Produced by Rass Health Care, ADC combines Ampicillin (250mg) with Dicloxacillin (250mg). This combination is particularly useful in treating infections caused by both penicillin-sensitive and penicillinase-producing organisms.
3. Alnaclox LB
Manufactured by Alna Biotech, Alnaclox LB is a unique combination of Dicloxacillin, Amoxycillin, and Lactobacillus Sporegens. The addition of probiotics (Lactobacillus) may help in maintaining gut health while undergoing antibiotic treatment.
4. Baxin-D-LB+
Hetero Healthcare Ltd. produces Baxin-D-LB+, which contains Amoxicillin (250mg), Dicloxacillin (250mg), and Lactobacillus Sporogenes (250 Million cells). This combination not only provides broad-spectrum antibiotic coverage but also supports gut health with the inclusion of probiotics.
Pharmaceutical Companies Manufacturing Dicloxacillin Combinations
Several pharmaceutical companies are involved in the production of Dicloxacillin combination medications. Some of the prominent manufacturers include:
- Centaur Pharmaceuticals Pvt Ltd
- Rass Health Care
- Alna Biotech
- Active HC
- Vensat Bio
- Piramal Healthcare
- Hetero Healthcare Ltd.
- Kee Pharma Ltd.
These companies play a crucial role in ensuring the availability of diverse Dicloxacillin combination products in the market, catering to different patient needs and preferences.
Dosage and Administration of Dicloxacillin Combinations
The dosage and administration of Dicloxacillin combinations can vary depending on the specific brand, formulation, and the condition being treated. However, some general guidelines can be observed:
What are common dosages for Dicloxacillin combinations?
Many Dicloxacillin combinations come in dosages of 250mg/250mg, meaning they contain 250mg of Dicloxacillin and 250mg of another antibiotic (usually Amoxicillin or Ampicillin). For example, brands like Amclox-DL, Amsat, and Baxin-D all follow this dosage pattern.
How should Dicloxacillin combinations be administered?
The method of administration depends on the formulation:
- Oral formulations (tablets, capsules, syrups) are typically taken by mouth, usually every 6 hours or as directed by a healthcare provider.
- Topical formulations (creams, gels, ointments) are applied directly to the affected area of the skin.
- Injectable forms are administered by a healthcare professional, usually in a clinical setting.
It’s crucial to follow the prescribed dosage and complete the full course of treatment, even if symptoms improve before the medication is finished.
Potential Side Effects and Precautions
While Dicloxacillin combinations are generally well-tolerated, they can cause side effects in some individuals. It’s important to be aware of potential adverse reactions and take necessary precautions.
What are common side effects of Dicloxacillin combinations?
Common side effects may include:
- Nausea and vomiting
- Diarrhea
- Stomach pain
- Skin rash
- Headache
In rare cases, more severe allergic reactions can occur. Patients should seek immediate medical attention if they experience symptoms such as difficulty breathing, severe skin reactions, or signs of anaphylaxis.
What precautions should be taken when using Dicloxacillin combinations?
Consider the following precautions:
- Inform your healthcare provider about any allergies, especially to penicillin or other antibiotics.
- Disclose all medications you’re currently taking to avoid potential drug interactions.
- If you’re pregnant or breastfeeding, consult your doctor before using Dicloxacillin combinations.
- Follow the prescribed dosage and complete the full course of treatment to prevent antibiotic resistance.
The Future of Dicloxacillin Combinations
As antibiotic resistance continues to be a global concern, the development and use of antibiotic combinations like those containing Dicloxacillin remain an important area of focus in the pharmaceutical industry.
How is the market for Dicloxacillin combinations evolving?
The market for Dicloxacillin combinations is dynamic, with new formulations and brands regularly being introduced. As stated in the original text, the drug directory is constantly being updated as new generics and brands receive authorization from drug regulatory authorities and start appearing in pharmacies.
What role do Dicloxacillin combinations play in combating antibiotic resistance?
Antibiotic combinations can help in managing antibiotic resistance by:
- Providing broader spectrum coverage, reducing the likelihood of resistant bacteria surviving treatment
- Allowing for lower doses of individual antibiotics, potentially reducing side effects
- Enabling more targeted treatments when the causative organism is unknown
However, it’s crucial to use these combinations judiciously and only when necessary to prevent further development of antibiotic resistance.
Conclusion: The Importance of Dicloxacillin Combinations in Modern Medicine
Dicloxacillin combinations play a significant role in treating various bacterial infections. With 62 brand names currently available in the market, healthcare providers have a wide array of options to choose from when prescribing these medications. The diversity in formulations, dosages, and combinations allows for personalized treatment approaches, catering to individual patient needs and specific infection types.
As we continue to face challenges with antibiotic resistance, the judicious use of Dicloxacillin combinations, along with ongoing research and development in this field, will remain crucial in our fight against bacterial infections. Patients and healthcare providers alike should stay informed about the available options, potential side effects, and best practices for using these important medications.
Remember, while this article provides a comprehensive overview of Dicloxacillin combination brand names and their uses, it’s always essential to consult with a healthcare professional for personalized medical advice and treatment recommendations.
SNo | Brand Name | Combination Generics | Manufacturers | Price | |
1 |
| Amoxycillin (250mg) + Dicloxacillin (250mg) | Centaur Pharmaceuticals Pvt Ltd | View Price | |
2 |
| Ampicillin 250mg + Diclocillin 250mg | Rass Health Care | View Price | |
3 |
| Dicloxacillin, Amoxycillin, Lactobacillus Sporegens | Alna Biotech | View Price | |
4 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Active HC | View Price | |
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5 |
| Ampicillin 250mg + Diclocillin 250mg | Vensat Bio | View Price | |
6 |
| Dicloxacillin, Cefixime | Piramal Healthcare | View Price | |
7 |
| Dicloxacillin, Amoxycillin, Lacto Bacillus Sporegens | Hetero Healthcare Ltd.![]() | View Price | |
8 |
| Ampicillin 250mg + Diclocillin 250mg | Hetero Healthcare Ltd. | View Price | |
9 |
| Ampicillin 250mg + Diclocillin 250mg + Lactobacillus Spogenes 60million cells | Hetero Healthcare Ltd. | View Price | |
10 |
| Amoxicillin 250mg + Dicloxacillin 250mg +Lactobacillus Sporogenes 250 Million cells | Hetero Healthcare Ltd.![]() | View Price | |
11 |
| Dicloxacillin, Amoxycillin, Lacto Bacillus Sporegens | Kee Pharma Ltd. | View Price | |
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12 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Blubell Pharma | View Price | |
13 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Blue Cross Laboratories Ltd.![]() | View Price | |
14 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Biomiicron Pharma India Pvt. Ltd. | View Price | |
15 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Little Greave Pharmaceuticals Pvt. Ltd. | View Price | |
16 |
| Cefixime Trihydrate 200mg + Dicloxacillin 500mg | Aden Healthcare | View Price | |
17 |
| Dicloxacillin, Cefixime | Iscon Life Sciences | View Price | |
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18 |
| Cefixime 200mg + Dicloxacillin 250mg | Talent Healthcare | View Price | |
19 |
| Cefixime 200mg + Dicloxacillin 500mg | Talent Healthcare | View Price | |
20 |
| Cefixime 200mg + Dicloxacillin 500mg | Elkos Healthcare Pvt.![]() | View Price | |
21 |
| Dicloxacillin, Cefixime | Welkind Pharma | View Price | |
22 |
| Dicloxacillin, Cefixime, Lacto Bacillus Sporegens | Centaur Pharmaceuticals Pvt. Ltd. | View Price | |
23 |
| Dicloxacillin, Cefixime | Alna Biotech | View Price | |
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24 |
| Cefixime Trihydrate 200mg + Dicloxacillin 500mg | Edward Young Labs | View Price | |
25 |
| Dicloxacillin, Amoxicillin Trihydrate, Lactic Acid Bacillus | Bestochem Formulations (India) Ltd.![]() | View Price | |
26 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Micro Labs Ltd (Eros) | View Price | |
27 |
| Cefixime Trihydarte 200mg + Dicloxacillin 500mg | Pax Healthcare | View Price | |
28 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Intra Labs India Pvt.![]() | View Price | |
29 |
| Amoxicillin 125mg + Dicloxacillin 125mg | Medopharm | View Price | |
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30 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Medopharm | View Price | |
31 |
| Ampicillin 250mg + Diclocillin 250mg | Epitome Life Sciences | View Price | |
32 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Epitome Life Sciences | View Price | |
33 |
| Dicloxacillin, Amoxycillin, Lactobacillus Sporegens | Ethix Health Care | View Price | |
34 |
| Amoxicillin 250mg + Dicloxacillin 250mg | FDC Limited | View Price | |
35 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Wonder Products (Forrit) | View Price | |
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36 |
| Dicloxacillin, Cefixime, Lacto Bacillus Sporegens | Elder Pharmaceuticals Pvt.![]() | View Price | |
37 |
| Ampicillin Trihydrate 250mg + Diclocillin 250mg | Madhav BiotechPvt. Ltd. | View Price | |
38 |
| Dicloxacillin, Cefixime, Lacto Bacillus Sporegens | Hetero Healthcare Ltd. | View Price | |
39 |
| Amoxicillin 125mg + Dicloxacillin 125mg | Intra Labs India Pvt.![]() | View Price | |
40 |
| Amoxicillin 250mg + Dicloxacillin 250mg + Serrapeptase 15mg | Intra Labs India Pvt. Ltd. | View Price | |
41 |
| Dicloxacillin 250mg | Hetero Healthcare Ltd. | View Price | |
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42 |
| Dicloxacillin 500mg | Hetero Healthcare Ltd.![]() | View Price | |
43 |
| Dicloxacillin, Cefixime | Laborate Pharmaceuticals India Ltd. (Multicure) | View Price | |
44 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Lupin Laboratories Ltd. | View Price | |
45 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Aden Healthcare | View Price | |
46 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Uniflex | View Price | |
47 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Progressive Life Care | View Price | |
48 |
| Cefixime Trihydarte 200mg + Dicloxacillin 500mg | Acinom Healthcare | View Price | |
49 |
| Amoxicillin 125mg + Dicloxacillin 125mg | Cipla Limited | View Price | |
50 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Cipla Limited | View Price | |
51 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Cipla Limited | View Price | |
52 |
| Dicloxacillin, Amoxycillin, Lactic Acid Bacillus | Ankare Pharmaceuticals | View Price | |
53 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Ankare | View Price | |
54 |
| Dicloxacillin, Amoxycillin, Lactobacillus Sporegens | Solitaire Pharmacia Pvt.![]() | View Price | |
55 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Rass Health Care | View Price | |
56 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Rishab Health Care Pvt. Ltd. (Orochem) | View Price | |
57 |
| Dicloxacillin, Amoxycillin, Lactic Acid Bacillus | Monad Pharmaceuticals | View Price | |
58 |
| Amoxicillin 250mg + Dicloxacillin 250mg + Lactobacillus Sporogenes 2.5 Billion Cells | AHPL | View Price | |
59 |
| Cefixime 200mg + Dicloxacillin 500mg + Lactobacillus Sporogenes 60 Million cells | Wockhardt Limited (Orion) | View Price | |
60 |
| Cefpodoxime Proxetil 200mg + Dicloxacillin 500mg | Macleods Pharmaceuticals Ltd.![]() | View Price | |
61 |
| Dicloxacillin, Cefixime, Lactobacillus Sporegens | FDC Limited (Spectra) | View Price | |
62 |
| Dicloxacillin, Cefixime, Lactobacillus Sporegens | FDC Ltd | View Price |
Dicloxacillin
Dicloxacillin
Penicillin (penicillinase-resistant penicillin)
Staphylococcus spp. , Streptococcal spp.
Exerts bactericidal activity via inhibition of bacterial
cell wall synthesis by binding one or more of the penicillin binding proteins (PBPs).
Exerts bacterial autolytic effect by inhibition of certain PBPs related to the
activation of a bacterial autolytic process.
Penicillins
produce time-dependent killing
Cmax: 10-17mcg/ml; Oral bioavailability: 37%; Half-life:
0.8 hours; Table 6
Hematologic: agranulocytosis, eosinophilia, hemolytic
anemia, neutropenia, inhibition of platelet aggregation
Renal: interstitial nephritis
CNS: seizures
Other: Jarisch-Herxheimer Reaction (fever, chills,
sweating, tachycardia, hyperventilation, flushing, and myalgia)
Adults: 125-250 mg po q6h
Pediatric: > 1 month and < 40 kg: 12.5 – 25 mg/kg/day po in 4 divided doses
40 kg: usual adult dose
Staphylococcal osteomyelitis:
50-100 mg/kg/day in 4 divided doses
Disease state based dosing:
Renal failure: not necessary
Contraindications/Warnings/Precautions:
Contraindications: Anaphylaxis to dicloxacillin or other
penicillins
Precautions: Cephalosporin hypersensitivity
Dicloxacillin is an inducer of the cytochrome P450 3A4
isoenzyme. Caution should be exercised and monitoring is suggested when
concomitantly administering dicloxacillin with drugs that have narrow
therapeutic windows and are substrates of the CYP3A4 enzyme.
Contraceptives – decreased contraceptive effectiveness
Live Typhoid
Vaccine – decreased immunological response to the typhoid
vaccine
Probenecid – increased dicloxacillin levels
Warfarin – decreased anticoagulant effectiveness
Pregnancy:
Category B: No evidence of risk in humans
but studies inadequate.
Monitoring Requirements:
Therapeutic:
Culture and sensitivities, signs and symptoms of infection
Toxic: Periodic
CBC, urinalysis, BUN, Creatinine, AST and ALT
Brand names/Manufacturer:
- AMCIDIL (Macrophar –
THAILAND) - AMPICLOX-D (Sanfer –
MEXICO) - AMPIPLUS (Menarini – ITALY)
- BRISPEN (Bristol-Myers
Squibb – MEXICO) - CILPEN (Antibioticos –
MEXICO) - CLOMICIN (IQFA – MEXICO)
- CLOXIL (Ofimex – MEXICO)
- CLOXIPEN (Welfer – MEXICO)
- CLOXYDIN (Biomedis –
THAILAND) - DIAMPLICIL (Pharmacia –
ITALY) - DICHLOR-STAPENOR (Bayer –
GERMANY) - DICIL (Chemil – ITALY)
- DICILLIN (Durascan –
DENMARK) - DICLEX (Meiji – THAILAND)
- DICLOCIL (Bristol-Myers
Squibb SWEDEN, NORWAY, AUSTRALIA, DENMARK, PORTUGAL, THAILAND, FINLAND, NEW
ZEALAND, GREECE, FRANCE, NETHERLANDS, BELGIUM, HONG KONG) - DICLOCILLIN (TO-Chemicals
THAILAND, ITALY) - DICLO (FIRMA – ITALY)
- DICLOSON (Unison –
THAILAND) - DICLO-TECNO (Tecnofarma –
MEXICO) - DICLOXACILLIN (Sandoz –
U.S.)
- DICLOXACILLIN SODIUM (Teva
– USA) - DICLOXAN (IBI – ITALY)
- DICLOX (PP Lab – THAILAND)
- DICLOXIA (Asian Pharm –
THAILAND) - DICLOXIN (Olan-Kemed –
THAILAND) - DICLOXMAN (T Man –
THAILAND) - DICLOXNO (Milano –
THAILAND) - DICLOXSIG (Sigma –
AUSTRALIA) - DIFLOR (Coli – ITALY)
- DILOXIN (Pond’s – THAILAND)
- DIPXAPEN (Liferpal –
MEXICO) - DISTAPH (Alphapharm –
AUSTRALIA) - DITTEROLINA (Fustery –
MEXICO) - DITUM (TNP – THAILAND)
- DIXEN (Maver – MEXICO)
- DIXOCILLIN (Siam Bheasach –
THAILAND) - DOROX (M & H – THAILAND)
- DUPLAMOX (ISF – ITALY)
- DUPLEXCILLINA (Metapharma –
ITALY) - DUPLEXIL (Eurofarmaco –
ITALY) - DYCILL (GlaxoSmithKline –
USA) - DYCILL (SmithKline Beecham
– USA) - DYNAPEN – (Bristol Myers
USA, CANADA) - DYNAPEN (Apothecon – USA)
- DYNEPEN (Bristol Myers –
USA) - INFECTOSTAPH (Infectopharm
– GERMANY) - NOVAPEN (IBP – ITALY)
- PANAC (Bristol-Myers –
MEXICO) - PANAC K (Bristol-Myers –
MEXICO) - PATHOCIL (WYETH – USA)
- PENCLOX (Pisa – MEXICO)
- PENTIDIX (Maver – MEXICO)
- POSIPEN (Sanfer – MEXICO)
- SERVIDICLOX (Biochemie –
THAILAND) - TOTOCILLIN (Bayer GERMANY
– AUSTRIA) - VELAMOX D (GlaxoSmithKline
– ITALY)
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Dicloxacillin – instructions for use
Dicloxacillin
Instruction:
- Pharmacological action
- Indications
- Contraindications
- With care
- Pregnancy and breastfeeding
- Dosage and Administration
- Classification
Pharmacological action
Dicloxacillin is a narrow-spectrum antibiotic belonging to the penicillin class. It is used to treat infections caused by susceptible Gram-positive bacteria. Active against beta-lactamase producing organisms such as Staphylococcus aureus which are resistant to most penicillins.
Indications
Infections of the skin and subcutaneous tissue, pneumonia, osteomyelitis caused by strains of staphylococci that form beta-lactamase.
Contraindications
Hypersensitivity to dicloxacillin and penicillins
Precautions
Lactation.
Pregnancy and breastfeeding
Use in pregnancy
FDA fetal category B.
Adequate and strictly controlled studies on the safety of dicloxacillin during pregnancy have not been conducted.
Animal studies showed no evidence of fetal toxicity.
Dicloxacillin should be used during pregnancy only if the potential benefit to the mother outweighs the potential risk to the fetus.
Use during breastfeeding
It is not known whether dicloxacillin passes into human breast milk.
Side effects are unlikely in infants.
Caution is advised when prescribing to lactating women.
Dosage and administration
Inside.
Children < 40 kg: 12.5–50 mg/kg/day in 4 divided doses; with osteomyelitis - 50-100 mg / kg / day in 4 doses.
Children over 40 kg and adults: 125-500 mg 4 times a day.
Classification
ATX
J01CF01
Pharmacological groups
Antibiotics
Penicillins
FDA pregnancy category
B
(no risk in non-human studies)
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- INN
- Reviews
- Questions
- Latin name
- Chemical formula
Information about the active substance Dicloxacillin is intended for medical and pharmaceutical professionals, for reference purposes only.