Dicloxacillin brand name. Dicloxacillin Combination Brands: A Comprehensive Guide to 62 Medications
What are the various brand names for Dicloxacillin combination drugs. How many pharmaceutical companies produce generic versions of this medication. Which forms are available for Dicloxacillin combinations. What information is provided about pricing and manufacturers.
Overview of Dicloxacillin Combination Medications
Dicloxacillin is an antibiotic medication that is often combined with other drugs to create more effective treatments. This article examines the various brand names, manufacturers, and formulations of Dicloxacillin combination drugs available on the market. With 62 different brands listed, patients and healthcare providers have numerous options to choose from when selecting the most appropriate medication.
Common Combinations and Formulations
Dicloxacillin is frequently combined with other antibiotics to enhance its effectiveness. Some common combinations include:
- Dicloxacillin + Amoxicillin
- Dicloxacillin + Ampicillin
- Dicloxacillin + Cefixime
These medications are available in various forms to suit different patient needs:
- Tablets
- Capsules
- Syrups
- Creams
- Gels
- Ointments
- Liquids
- Injections
Top Manufacturers of Dicloxacillin Combination Drugs
Several pharmaceutical companies produce generic versions of Dicloxacillin combinations. Some of the notable manufacturers include:
- Centaur Pharmaceuticals Pvt Ltd
- Rass Health Care
- Alna Biotech
- Active HC
- Hetero Healthcare Ltd.
- Piramal Healthcare
- Kee Pharma Ltd.
Pricing and Availability of Dicloxacillin Combinations
The pricing of Dicloxacillin combination drugs varies depending on the brand, formulation, and dosage. To find the most up-to-date pricing information, consumers can click on the “View Price” link associated with each brand name in the drug directory. It’s important to note that prices may fluctuate over time and vary between different pharmacies and regions.
Factors Affecting Pricing
- Brand vs. generic versions
- Dosage strength
- Quantity per package
- Pharmaceutical company
- Geographic location
Popular Dicloxacillin Combination Brands
Among the 62 brands listed, some of the notable Dicloxacillin combination medications include:
- Abcloxx (Amoxycillin 250mg + Dicloxacillin 250mg)
- ADC (Ampicillin 250mg + Diclocillin 250mg)
- Alnaclox LB (Dicloxacillin, Amoxycillin, Lactobacillus Sporegens)
- Amclox-DL (Amoxicillin 250mg + Dicloxacillin 250mg)
- Baxin D LB+ (Dicloxacillin, Amoxycillin, Lacto Bacillus Sporegens)
Unique Formulations and Added Ingredients
Some Dicloxacillin combination drugs incorporate additional ingredients to enhance their effectiveness or provide additional benefits. For example:
- Lactobacillus Sporegens: Found in brands like Alnaclox LB and Baxin D LB+, this probiotic may help maintain gut health during antibiotic treatment.
- Cefixime: Combined with Dicloxacillin in brands like Asert D to provide broader spectrum antibiotic coverage.
Do these added ingredients improve treatment outcomes?
The inclusion of probiotics like Lactobacillus Sporegens may help reduce the risk of antibiotic-associated diarrhea and maintain a healthy gut microbiome. However, more research is needed to definitively prove the benefits of these combination formulations in clinical practice.
Choosing the Right Dicloxacillin Combination
When selecting a Dicloxacillin combination medication, several factors should be considered:
- The specific infection being treated
- Patient’s age and weight
- Allergies or sensitivities to certain antibiotics
- Dosage form preference (e.g., tablet vs. liquid)
- Cost and insurance coverage
- Potential drug interactions
It’s crucial to consult with a healthcare provider to determine the most appropriate Dicloxacillin combination for individual needs.
Potential Side Effects and Precautions
While Dicloxacillin combinations are generally safe and effective when used as directed, they may cause side effects in some patients. Common side effects may include:
- Nausea and vomiting
- Diarrhea
- Stomach pain
- Skin rash
- Allergic reactions (in rare cases)
How can patients minimize the risk of side effects?
To reduce the likelihood of experiencing side effects, patients should:
- Take the medication exactly as prescribed
- Complete the full course of antibiotics, even if symptoms improve
- Inform their healthcare provider of any allergies or previous adverse reactions to antibiotics
- Avoid alcohol consumption during treatment
- Take probiotics or eat probiotic-rich foods to support gut health
The Future of Dicloxacillin Combinations
As antibiotic resistance continues to be a global concern, research into new and improved antibiotic combinations is ongoing. Future developments in Dicloxacillin combinations may include:
- Novel drug combinations to combat resistant bacteria
- Improved formulations for enhanced bioavailability
- Targeted delivery systems for reduced side effects
- Integration of nanotechnology for more effective treatments
Will new Dicloxacillin combinations help address antibiotic resistance?
While innovative combinations may provide temporary solutions, addressing antibiotic resistance requires a multifaceted approach. This includes responsible antibiotic use, development of new classes of antibiotics, and implementation of antimicrobial stewardship programs in healthcare settings.
Regulatory Landscape and Drug Approval Process
The development and approval of new Dicloxacillin combinations involve rigorous testing and regulatory oversight. Key aspects of this process include:
- Preclinical studies to assess safety and efficacy
- Clinical trials in human subjects
- Review and approval by regulatory agencies (e.g., FDA, EMA)
- Post-marketing surveillance to monitor long-term safety and effectiveness
How long does it typically take for a new Dicloxacillin combination to reach the market?
The drug development and approval process can take several years, often ranging from 7 to 10 years or more. This timeline ensures thorough evaluation of safety and efficacy before a new medication becomes available to patients.
Global Availability and Access to Dicloxacillin Combinations
While Dicloxacillin combinations are widely available in many countries, access to these medications can vary significantly across different regions. Factors affecting global availability include:
- Local regulatory approvals
- Healthcare system infrastructure
- Economic factors and affordability
- Supply chain logistics
- National health policies and guidelines
How can access to Dicloxacillin combinations be improved in underserved regions?
Improving access to essential antibiotics like Dicloxacillin combinations in underserved areas requires multifaceted strategies:
- International collaborations to streamline regulatory processes
- Public-private partnerships to reduce manufacturing and distribution costs
- Implementation of tiered pricing models based on a country’s economic status
- Investment in local pharmaceutical manufacturing capabilities
- Education and training programs for healthcare providers on appropriate antibiotic use
Patient Education and Proper Use of Dicloxacillin Combinations
Ensuring proper use of Dicloxacillin combinations is crucial for maximizing treatment effectiveness and minimizing the risk of antibiotic resistance. Key points for patient education include:
- Understanding the importance of completing the full course of antibiotics
- Proper storage and handling of the medication
- Awareness of potential drug interactions
- Recognition of signs that may indicate an allergic reaction
- The importance of not sharing antibiotics with others
What role do pharmacists play in educating patients about Dicloxacillin combinations?
Pharmacists serve as crucial intermediaries between healthcare providers and patients, offering valuable guidance on medication use. They can:
- Provide detailed instructions on proper dosing and administration
- Explain potential side effects and how to manage them
- Offer advice on drug interactions and contraindications
- Answer patient questions and address concerns
- Reinforce the importance of antibiotic stewardship
Research and Development in Dicloxacillin Combinations
Ongoing research in the field of Dicloxacillin combinations aims to address current challenges and improve treatment outcomes. Some areas of focus include:
- Development of extended-release formulations for improved patient compliance
- Exploration of synergistic effects with novel antibiotic combinations
- Investigation of combination therapies targeting specific bacterial strains
- Utilization of artificial intelligence in drug discovery and development
- Assessment of Dicloxacillin combinations in treating antibiotic-resistant infections
How might emerging technologies impact the future of Dicloxacillin combination research?
Emerging technologies have the potential to revolutionize antibiotic research and development:
- AI and machine learning can accelerate the drug discovery process by predicting effective combinations
- CRISPR gene editing may enable the creation of highly targeted antibiotic therapies
- Nanotechnology could improve drug delivery and enhance the efficacy of existing combinations
- Microfluidic devices may facilitate rapid screening of novel antibiotic combinations
- Big data analytics can help identify patterns in antibiotic resistance and guide treatment strategies
As research in these areas progresses, we may see significant advancements in the development and application of Dicloxacillin combinations, potentially leading to more effective treatments and improved patient outcomes.
| SNo | Brand Name | Combination Generics | Manufacturers | Price | |
| 1 |
| Amoxycillin (250mg) + Dicloxacillin (250mg) | Centaur Pharmaceuticals Pvt Ltd | View Price | |
| 2 |
| Ampicillin 250mg + Diclocillin 250mg | Rass Health Care | View Price | |
| 3 |
| Dicloxacillin, Amoxycillin, Lactobacillus Sporegens | Alna Biotech | View Price | |
| 4 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Active HC | View Price | |
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| 5 |
| Ampicillin 250mg + Diclocillin 250mg | Vensat Bio | View Price | |
| 6 |
| Dicloxacillin, Cefixime | Piramal Healthcare | View Price | |
| 7 |
| Dicloxacillin, Amoxycillin, Lacto Bacillus Sporegens | Hetero Healthcare Ltd. | View Price | |
| 8 |
| Ampicillin 250mg + Diclocillin 250mg | Hetero Healthcare Ltd. | View Price | |
| 9 |
| Ampicillin 250mg + Diclocillin 250mg + Lactobacillus Spogenes 60million cells | Hetero Healthcare Ltd. | View Price | |
| 10 |
| Amoxicillin 250mg + Dicloxacillin 250mg +Lactobacillus Sporogenes 250 Million cells | Hetero Healthcare Ltd. | View Price | |
| 11 |
| Dicloxacillin, Amoxycillin, Lacto Bacillus Sporegens | Kee Pharma Ltd. | View Price | |
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| 12 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Blubell Pharma | View Price | |
| 13 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Blue Cross Laboratories Ltd. | View Price | |
| 14 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Biomiicron Pharma India Pvt. Ltd. | View Price | |
| 15 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Little Greave Pharmaceuticals Pvt. Ltd. | View Price | |
| 16 |
| Cefixime Trihydrate 200mg + Dicloxacillin 500mg | Aden Healthcare | View Price | |
| 17 |
| Dicloxacillin, Cefixime | Iscon Life Sciences | View Price | |
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| 18 |
| Cefixime 200mg + Dicloxacillin 250mg | Talent Healthcare | View Price | |
| 19 |
| Cefixime 200mg + Dicloxacillin 500mg | Talent Healthcare | View Price | |
| 20 |
| Cefixime 200mg + Dicloxacillin 500mg | Elkos Healthcare Pvt. Ltd. | View Price | |
| 21 |
| Dicloxacillin, Cefixime | Welkind Pharma | View Price | |
| 22 |
| Dicloxacillin, Cefixime, Lacto Bacillus Sporegens | Centaur Pharmaceuticals Pvt. Ltd. | View Price | |
| 23 |
| Dicloxacillin, Cefixime | Alna Biotech | View Price | |
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| 24 |
| Cefixime Trihydrate 200mg + Dicloxacillin 500mg | Edward Young Labs | View Price | |
| 25 |
| Dicloxacillin, Amoxicillin Trihydrate, Lactic Acid Bacillus | Bestochem Formulations (India) Ltd. | View Price | |
| 26 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Micro Labs Ltd (Eros) | View Price | |
| 27 |
| Cefixime Trihydarte 200mg + Dicloxacillin 500mg | Pax Healthcare | View Price | |
| 28 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Intra Labs India Pvt. Ltd. (Intra Life) | View Price | |
| 29 |
| Amoxicillin 125mg + Dicloxacillin 125mg | Medopharm | View Price | |
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| 30 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Medopharm | View Price | |
| 31 |
| Ampicillin 250mg + Diclocillin 250mg | Epitome Life Sciences | View Price | |
| 32 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Epitome Life Sciences | View Price | |
| 33 |
| Dicloxacillin, Amoxycillin, Lactobacillus Sporegens | Ethix Health Care | View Price | |
| 34 |
| Amoxicillin 250mg + Dicloxacillin 250mg | FDC Limited | View Price | |
| 35 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Wonder Products (Forrit) | View Price | |
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| 36 |
| Dicloxacillin, Cefixime, Lacto Bacillus Sporegens | Elder Pharmaceuticals Pvt. Ltd. | View Price | |
| 37 |
| Ampicillin Trihydrate 250mg + Diclocillin 250mg | Madhav BiotechPvt. Ltd. | View Price | |
| 38 |
| Dicloxacillin, Cefixime, Lacto Bacillus Sporegens | Hetero Healthcare Ltd. | View Price | |
| 39 |
| Amoxicillin 125mg + Dicloxacillin 125mg | Intra Labs India Pvt. Ltd. | View Price | |
| 40 |
| Amoxicillin 250mg + Dicloxacillin 250mg + Serrapeptase 15mg | Intra Labs India Pvt. Ltd. | View Price | |
| 41 |
| Dicloxacillin 250mg | Hetero Healthcare Ltd. | View Price | |
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| 42 |
| Dicloxacillin 500mg | Hetero Healthcare Ltd. | View Price | |
| 43 |
| Dicloxacillin, Cefixime | Laborate Pharmaceuticals India Ltd. (Multicure) | View Price | |
| 44 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Lupin Laboratories Ltd. | View Price | |
| 45 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Aden Healthcare | View Price | |
| 46 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Uniflex | View Price | |
| 47 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Progressive Life Care | View Price | |
| 48 |
| Cefixime Trihydarte 200mg + Dicloxacillin 500mg | Acinom Healthcare | View Price | |
| 49 |
| Amoxicillin 125mg + Dicloxacillin 125mg | Cipla Limited | View Price | |
| 50 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Cipla Limited | View Price | |
| 51 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Cipla Limited | View Price | |
| 52 |
| Dicloxacillin, Amoxycillin, Lactic Acid Bacillus | Ankare Pharmaceuticals | View Price | |
| 53 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Ankare | View Price | |
| 54 |
| Dicloxacillin, Amoxycillin, Lactobacillus Sporegens | Solitaire Pharmacia Pvt. Ltd. (CureMax) | View Price | |
| 55 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Rass Health Care | View Price | |
| 56 |
| Amoxicillin 250mg + Dicloxacillin 250mg | Rishab Health Care Pvt. Ltd. (Orochem) | View Price | |
| 57 |
| Dicloxacillin, Amoxycillin, Lactic Acid Bacillus | Monad Pharmaceuticals | View Price | |
| 58 |
| Amoxicillin 250mg + Dicloxacillin 250mg + Lactobacillus Sporogenes 2.5 Billion Cells | AHPL | View Price | |
| 59 |
| Cefixime 200mg + Dicloxacillin 500mg + Lactobacillus Sporogenes 60 Million cells | Wockhardt Limited (Orion) | View Price | |
| 60 |
| Cefpodoxime Proxetil 200mg + Dicloxacillin 500mg | Macleods Pharmaceuticals Ltd. (Oxalis) | View Price | |
| 61 |
| Dicloxacillin, Cefixime, Lactobacillus Sporegens | FDC Limited (Spectra) | View Price | |
| 62 |
| Dicloxacillin, Cefixime, Lactobacillus Sporegens | FDC Ltd | View Price | |
5 Billion Cells)Dicloxacillin
Dicloxacillin
Penicillin (penicillinase-resistant penicillin)
Staphylococcus spp.
, Streptococcal spp.
Exerts bactericidal activity via inhibition of bacterial
cell wall synthesis by binding one or more of the penicillin binding proteins (PBPs).
Exerts bacterial autolytic effect by inhibition of certain PBPs related to the
activation of a bacterial autolytic process.
Penicillins
produce time-dependent killing
Cmax: 10-17mcg/ml; Oral bioavailability: 37%; Half-life:
0.8 hours; Table 6
Hematologic: agranulocytosis, eosinophilia, hemolytic
anemia, neutropenia, inhibition of platelet aggregation
Renal: interstitial nephritis
CNS: seizures
Other: Jarisch-Herxheimer Reaction (fever, chills,
sweating, tachycardia, hyperventilation, flushing, and myalgia)
Adults: 125-250 mg po q6h
Pediatric: > 1 month and < 40 kg: 12.5 – 25 mg/kg/day po in 4 divided doses
40 kg: usual adult dose
Staphylococcal osteomyelitis:
50-100 mg/kg/day in 4 divided doses
Disease state based dosing:
Renal failure: not necessary
Contraindications/Warnings/Precautions:
Contraindications: Anaphylaxis to dicloxacillin or other
penicillins
Precautions: Cephalosporin hypersensitivity
Dicloxacillin is an inducer of the cytochrome P450 3A4
isoenzyme.
Caution should be exercised and monitoring is suggested when
concomitantly administering dicloxacillin with drugs that have narrow
therapeutic windows and are substrates of the CYP3A4 enzyme.
Contraceptives – decreased contraceptive effectiveness
Live Typhoid
Vaccine – decreased immunological response to the typhoid
vaccine
Probenecid – increased dicloxacillin levels
Warfarin – decreased anticoagulant effectiveness
Pregnancy:
Category B: No evidence of risk in humans
but studies inadequate.
Monitoring Requirements:
Therapeutic:
Culture and sensitivities, signs and symptoms of infection
Toxic: Periodic
CBC, urinalysis, BUN, Creatinine, AST and ALT
Brand names/Manufacturer:
- AMCIDIL (Macrophar –
THAILAND) - AMPICLOX-D (Sanfer –
MEXICO) - AMPIPLUS (Menarini – ITALY)
- BRISPEN (Bristol-Myers
Squibb – MEXICO) - CILPEN (Antibioticos –
MEXICO) - CLOMICIN (IQFA – MEXICO)
- CLOXIL (Ofimex – MEXICO)
- CLOXIPEN (Welfer – MEXICO)
- CLOXYDIN (Biomedis –
THAILAND) - DIAMPLICIL (Pharmacia –
ITALY) - DICHLOR-STAPENOR (Bayer –
GERMANY) - DICIL (Chemil – ITALY)
- DICILLIN (Durascan –
DENMARK) - DICLEX (Meiji – THAILAND)
- DICLOCIL (Bristol-Myers
Squibb SWEDEN, NORWAY, AUSTRALIA, DENMARK, PORTUGAL, THAILAND, FINLAND, NEW
ZEALAND, GREECE, FRANCE, NETHERLANDS, BELGIUM, HONG KONG) - DICLOCILLIN (TO-Chemicals
THAILAND, ITALY) - DICLO (FIRMA – ITALY)
- DICLOSON (Unison –
THAILAND) - DICLO-TECNO (Tecnofarma –
MEXICO) - DICLOXACILLIN (Sandoz –
U.
S.) - DICLOXACILLIN SODIUM (Teva
– USA) - DICLOXAN (IBI – ITALY)
- DICLOX (PP Lab – THAILAND)
- DICLOXIA (Asian Pharm –
THAILAND) - DICLOXIN (Olan-Kemed –
THAILAND) - DICLOXMAN (T Man –
THAILAND) - DICLOXNO (Milano –
THAILAND) - DICLOXSIG (Sigma –
AUSTRALIA) - DIFLOR (Coli – ITALY)
- DILOXIN (Pond’s – THAILAND)
- DIPXAPEN (Liferpal –
MEXICO) - DISTAPH (Alphapharm –
AUSTRALIA) - DITTEROLINA (Fustery –
MEXICO) - DITUM (TNP – THAILAND)
- DIXEN (Maver – MEXICO)
- DIXOCILLIN (Siam Bheasach –
THAILAND) - DOROX (M & H – THAILAND)
- DUPLAMOX (ISF – ITALY)
- DUPLEXCILLINA (Metapharma –
ITALY) - DUPLEXIL (Eurofarmaco –
ITALY) - DYCILL (GlaxoSmithKline –
USA) - DYCILL (SmithKline Beecham
– USA) - DYNAPEN – (Bristol Myers
USA, CANADA) - DYNAPEN (Apothecon – USA)
- DYNEPEN (Bristol Myers –
USA) - INFECTOSTAPH (Infectopharm
– GERMANY) - NOVAPEN (IBP – ITALY)
- PANAC (Bristol-Myers –
MEXICO) - PANAC K (Bristol-Myers –
MEXICO) - PATHOCIL (WYETH – USA)
- PENCLOX (Pisa – MEXICO)
- PENTIDIX (Maver – MEXICO)
- POSIPEN (Sanfer – MEXICO)
- SERVIDICLOX (Biochemie –
THAILAND) - TOTOCILLIN (Bayer GERMANY
– AUSTRIA) - VELAMOX D (GlaxoSmithKline
– ITALY)
S.)
|
Dicloxacillin – instructions for use
Dicloxacillin
Instruction:
- Pharmacological action
- Indications
- Contraindications
- With care
- Pregnancy and breastfeeding
- Dosage and Administration
- Classification
Pharmacological action
Dicloxacillin is a narrow-spectrum antibiotic belonging to the penicillin class.
It is used to treat infections caused by susceptible Gram-positive bacteria. Active against beta-lactamase producing organisms such as Staphylococcus aureus which are resistant to most penicillins.
Indications
Infections of the skin and subcutaneous tissue, pneumonia, osteomyelitis caused by strains of staphylococci that form beta-lactamase.
Contraindications
Hypersensitivity to dicloxacillin and penicillins
Precautions
Lactation.
Pregnancy and breastfeeding
Use in pregnancy
FDA fetal category B.
Adequate and strictly controlled studies on the safety of the use of dicloxacillin during pregnancy have not been conducted.
Animal studies showed no evidence of fetal toxicity.
Dicloxacillin should be used during pregnancy only if the potential benefit to the mother outweighs the potential risk to the fetus.
Use during breastfeeding
It is not known whether dicloxacillin passes into human breast milk.
Side effects are unlikely in infants.
Caution is advised when prescribing to lactating women.
Dosage and administration
Inside.
Children < 40 kg: 12.5–50 mg/kg/day in 4 divided doses; with osteomyelitis - 50-100 mg / kg / day in 4 doses.
Children over 40 kg and adults: 125-500 mg 4 times a day.
Classification
ATX
J01CF01
Pharmacological groups
Antibiotics
Penicillins
FDA pregnancy category
B
(no risk in non-human studies)
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Information about the active substance Dicloxacillin is intended for medical and pharmaceutical professionals, for reference purposes only.