What are the potential side effects of DMSO cream. How is dimethyl sulfoxide used medically. What conditions can DMSO potentially treat. Are there risks associated with using DMSO without medical supervision.

What is DMSO and How Does It Work?

Dimethyl sulfoxide (DMSO) is a colorless chemical solvent originally discovered as a byproduct of paper manufacturing in 19th century Germany. Its unique ability to penetrate biological membranes and transport small molecules through the skin caught the attention of scientists in the 1960s. Since then, researchers have investigated DMSO’s potential medical applications and associated risks.

DMSO works by easily absorbing into the skin and other tissues. This property allows it to potentially deliver medications topically and reduce inflammation when applied to the body. However, its mechanism of action is not fully understood for all proposed uses.

Key Properties of DMSO:

• Colorless liquid solvent
• Penetrates skin and biological membranes
• Can transport other small molecules
• Potential anti-inflammatory effects
• Absorbs quickly into tissues

FDA-Approved Uses of DMSO

Currently, the U.S. Food and Drug Administration (FDA) has approved only one medical use for DMSO. It is marketed under the brand name RIMSO-50 for treating interstitial cystitis, a chronic bladder condition.

For patients with interstitial cystitis, DMSO has demonstrated several benefits:

• Reduces pain associated with the condition
• Helps relax the bladder
• Increases bladder capacity

DMSO is administered as a bladder wash or installation for this approved use. A healthcare provider inserts the solution directly into the bladder via catheter.

Potential Off-Label Uses and Benefits of DMSO

While only approved for interstitial cystitis, DMSO has been investigated for various other potential medical applications. These off-label uses are not currently FDA-approved, and more research is needed to establish their safety and efficacy.

Potential off-label uses of DMSO include:

1. Treating arthritis pain and inflammation
2. Managing cancer-related symptoms
3. Alleviating chemotherapy side effects
4. Reducing general pain and inflammation
5. Serving as a vehicle for topical drug administration

Is DMSO effective for pain relief? Some studies suggest DMSO may help reduce inflammation and pain when applied topically. Its ability to penetrate the skin quickly makes it a potential alternative to other pain medications. However, more extensive clinical trials are needed to confirm its effectiveness and safety for widespread use as a pain reliever.

DMSO in Cancer Treatment

Can DMSO help with cancer treatment? Recent research has explored DMSO’s potential role in cancer therapy. A 2020 study published in the Journal of Medical Discovery found evidence suggesting DMSO may inhibit certain cancer cells. Additionally, some researchers have investigated its use in reducing chemotherapy medication leakage during administration.

However, it’s crucial to note that research in this area is still in its early stages. Much more extensive study is required before any definitive conclusions can be drawn about DMSO’s efficacy in cancer treatment or management.

Common Side Effects of DMSO

While many reported side effects of DMSO are relatively mild, the severity of reactions can increase with higher doses. It’s essential to understand these potential adverse effects before considering DMSO use.

What is the most common side effect of DMSO?

The most frequently reported side effect of DMSO use is a garlic-like taste and odor in the mouth and throat. This occurs because DMSO breaks down into dimethyl sulfide, which produces this characteristic smell.

Other potential side effects include:

• Headache
• Nausea
• Vomiting
• Stomach discomfort
• Diarrhea
• Fever or chills
• Decreased heart rate
• Skin reactions (itching, rash, or skin thickening)

The likelihood and severity of these side effects typically correlate with the amount of DMSO used. Therefore, it’s crucial to follow proper dosing guidelines under medical supervision.

Risks and Precautions When Using DMSO

While DMSO is available for purchase online, using it without proper medical guidance can pose significant risks. Understanding these potential dangers is essential for anyone considering DMSO use.

Increased Risk of Medication Interactions

DMSO may enhance the effects of certain medications, potentially leading to serious reactions. Medications that may interact with DMSO include:

• Sedatives
• Blood thinners
• Steroids

Does DMSO interact with other medications? Yes, DMSO can potentially interact with various drugs, either increasing their absorption or altering their effects. This is why it’s crucial to consult with a healthcare provider before using DMSO, especially if you’re taking other medications.

Risk of Overuse

The easy availability of DMSO online may lead to unsupervised use and potential overuse. Without proper medical guidance, individuals may use incorrect dosages or apply DMSO for unapproved purposes, increasing the risk of adverse effects.

Quality Control Concerns

DMSO products purchased online or from unregulated sources may vary in purity and concentration. This inconsistency can lead to unpredictable effects and potential contamination risks.

How is DMSO Administered?

The method of DMSO administration depends on its intended use and formulation. Common routes of administration include:

1. Topical application: DMSO can be applied to the skin as a gel or solution.
2. Bladder instillation: For treating interstitial cystitis, DMSO is administered directly into the bladder via catheter.

What is the proper way to apply DMSO topically? When using DMSO topically, it’s important to clean the application area thoroughly and apply the product as directed by a healthcare professional. The skin should be dry before application, and the area should be allowed to air dry after applying DMSO.

DMSO Research and Future Potential

Despite its limited FDA approval, DMSO continues to be the subject of ongoing research into its potential medical applications. Scientists are exploring its use in various fields, from pain management to cancer treatment.

Current Areas of DMSO Research

• Neuroprotective effects in brain injury
• Anti-inflammatory properties in autoimmune diseases
• Potential antiviral activities
• Role in enhancing drug delivery systems
• Effects on stem cell preservation and differentiation

While these areas show promise, it’s important to note that much of this research is still in preliminary stages. Rigorous clinical trials are needed to establish the safety and efficacy of DMSO for these potential uses.

Challenges in DMSO Research

Why isn’t DMSO more widely used in medicine? Several factors have limited the widespread adoption of DMSO in medical practice:

1. Limited FDA approval: Currently, DMSO is only approved for a single indication, restricting its use in other areas.
2. Variability in formulations: The lack of standardization in DMSO products makes it challenging to conduct consistent research.
3. Side effect profile: The potential for adverse effects, especially with improper use, has led to caution among medical professionals.
4. Need for more extensive clinical trials: Many potential uses of DMSO require further investigation through large-scale, controlled studies.

Safety Considerations and Best Practices

Given the potential risks associated with DMSO use, it’s crucial to follow safety guidelines and best practices. These precautions can help minimize the risk of adverse effects and ensure proper use of DMSO.

Consulting Healthcare Professionals

Before using DMSO for any purpose, it’s essential to consult with a qualified healthcare provider. They can assess your individual health status, consider potential drug interactions, and provide guidance on appropriate use.

Proper Storage and Handling

How should DMSO be stored and handled? DMSO should be stored in a cool, dry place away from direct sunlight. It’s important to use clean, non-reactive containers for storage, as DMSO can dissolve certain plastics and rubbers. Always handle DMSO with care, using gloves to avoid skin contact when necessary.

Monitoring for Side Effects

When using DMSO, it’s important to be vigilant for any potential side effects. If you experience unusual symptoms or severe reactions, discontinue use and seek medical attention immediately.

Quality Assurance

If considering DMSO use, only obtain products from reputable sources. Look for pharmaceutical-grade DMSO that has been tested for purity and is free from contaminants.

By understanding the potential benefits, risks, and proper use of DMSO, individuals can make informed decisions about its use under appropriate medical supervision. As research continues, our understanding of this versatile compound and its applications in medicine may continue to evolve.

Uses, Benefits, Risks, and More

DMSO (Dimethyl Sulfoxide): Uses, Benefits, Risks, and More

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Medically reviewed by Angelica Balingit, MD — By Jessica DiGiacinto and Joe Bowman — Updated on May 16, 2023

DMSO is a colorless chemical solvent that may have many medical uses but is currently only approved by the FDA to treat interstitial cystitis.

The story of dimethyl sulfoxide (DMSO) is an unusual one. This by-product of the paper making process was discovered in Germany in the late 19th century. It’s a colorless liquid that gained notoriety for its ability to penetrate the skin and other biological membranes.

Scientists discovered that they could use DMSO as a transportation device to pass small molecules through skin in the 1960s. Since then, scientists have researched the potential benefits and risks of using DMSO to treat a variety of conditions. This research is ongoing.

DMSO was approved by the Food and Drug Administration (FDA)to treat interstitial cystitis (a chronic bladder issue) under the brand name RIMSO-50.

The compound has no other approved uses, but it’s been purported to be a treatment for:

• arthritis
• cancer
• chemotherapy side effects
• general pain

Because it absorbs easily into the skin, it’s also been studied as a vehicle for administering topical drugs.

In the late 70s, the FDA approved DMSO to help treat interstitial cystitis. It remains the only FDA-approved bladder installation (or bladder wash) for this condition. For individuals living with interstitial cystitis, DMSO has been shown to:

• ease pain due to the condition
• help relax the bladder
• increase bladder capacity

When it comes to off-label uses, DMSO is often employed as an alternative treatment to reduce inflammation and pain.

Because it absorbs easily into the skin, DMSO may be a beneficial alternative to other pain medications. However, further investigation into this area is needed before any conclusions can be drawn.

DMSO has also been touted for its ability to reduce the amount of leakage during chemotherapy administration, but more studies, and real-world usage, need to be done before it can be labeled as a trusted method.

Additionally, there has been some research into DMSO’s benefits when it comes to inhibiting cancer cells. A 2020 study published in the Journal of Medical Discovery found evidence of benefit. However, research is just beginning in this area, so many more studies need to be done before any conclusions can be made.

While many of the reported side effects of taking DMSO are mild, the amount of DMSO someone takes is directly correlated to the severity of the reaction.

One common side effect is the taste of garlic in the mouth and throat.

More severe side effects include:

• headache
• nausea
• vomiting
• stomach ache
• diarrhea
• fever
• chills
• a lowered heart rate
• itching
• rash
• rough or thickened skin

Risks

Because it’s seen as a more alternative treatment, DMSO is easy to find and buy online. However, buying this product and using it without a healthcare professional’s supervision could increase the likelihood of overuse.

DMSO may also increase the effect of a few medications, which could produce serious reactions in some people. A few medications DMSO may affect include:

• sedatives
• blood thinners
• steroids

DMSO can be administered

• topically, via a gel or solution
• as a bladder wash, via a catheter (for interstitial cystitis)

As with any alternative treatment, it’s always advised to talk with a doctor before deciding to purchase any product that contains DMSO. Dosage is directly connected to the severity of possible side effects.

Dimethyl sulfoxide (DMSO) is a chemical solvent that is sometimes used to help reduce inflammation and pain, and may also be beneficial in reducing leakage during chemotherapy treatment.

It has been FDA approved to treat only one condition: interstitial cystitis.

Because of possible interactions with other common medications, and lack of definitive research into its benefits, DMSO should not be used without medical supervision.

Last medically reviewed on February 1, 2022

How we reviewed this article:

Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.

• Capriotti K, et al. (2012). Dimethyl sulfoxide: History, chemistry, and clinical
  utility in dermatology.
  ncbi.nlm.nih.gov/pmc/articles/PMC3460663/
• Dimethylsulfoxide. (2020).
  mskcc.org/cancer-care/integrative-medicine/herbs/dimethylsulfoxide
• DMSO. (2009).
  ichelp.org/wp-content/uploads/2015/06/DMSO-Feb-2009.pdf
• Elisia I, et al. (2016). DMSO represses inflammatory cytokine production from human blood cells and reduces autoimmune arthritis.
  ncbi.nlm.nih.gov/pmc/articles/PMC4816398/
• Madsen BK, et al. (2018). Adverse reactions of dimethyl sulfoxide in humans: A systematic review.
  ncbi.nlm.nih.gov/pmc/articles/PMC6707402/
• Molecule of the week archive: Dimethyl sulfoxide. (2021).
  acs.org/content/acs/en/molecule-of-the-week/archive/d/dimethyl-sulfoxide.html?cid=home_motw
• Tang H, et al. (2020). DMSO inhibits growth and induces apoptosis through extrinsic pathway in human cancer cells.
  https://www.proquest.com/openview/06527232a660b6867effa2ff8f68deed/1?pq-origsite=gscholar&cbl=2050635
• Understanding unapproved use of approved drugs “off-label.” (2018).
  fda.gov/patients/learn-about-expanded-access-and-other-treatment-options/understanding-unapproved-use-approved-drugs-label
• Wengström Y, et al. (2008). European oncology nursing society extravasation guidelines.
  sciencedirect.com/science/article/abs/pii/S1462388908001002
• What is interstitial cystitis(IC)/bladder pain syndrome? (n.d.).
  urologyhealth.org/urology-a-z/i/interstitial-cystitis

Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available.

Current Version

May 16, 2023

Written By

Jessica DiGiacinto, Joe Bowman

Edited By

Jessica DiGiacinto

Copy Edited By

Delores Smith-Johnson

Feb 1, 2022

Medically Reviewed By

Angelica Balingit, MD

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Medically reviewed by Angelica Balingit, MD — By Jessica DiGiacinto and Joe Bowman — Updated on May 16, 2023

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DMSO – Health Information Library

Uses

DMSO (dimethyl sulfoxide) is a colorless, slightly oily liquid that is primarily used as an industrial solvent.

What Are Star Ratings?

Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

3 Stars
Reliable and relatively consistent scientific data showing a substantial health benefit.

2 Stars
Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.

1 Star
For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

This supplement has been used in connection with the following health conditions:

How It Works

How to Use It

DMSO is not indicated for healthy people. Those who do use this substance should consult a doctor familiar with its use. Some physicians do not recommend the use of DMSO due to concerns about safety and questions about efficacy. The potential for contamination exists in some DMSO products designed for industrial uses. DMSO used topically is rapidly absorbed through intact skin. Therefore, the area of skin (and the hands applying DMSO) must be clean, because anything on the skin will also be absorbed along with the DMSO.

Where to Find It

DMSO is derived from trees as a manufacturing by-product from the processing of paper. Metabolites (breakdown products) of DMSO, such as the sulfide and sulfone forms, are naturally present in the human body. However, the role of these in the body is not clear.

Possible Deficiencies

DMSO is not an essential nutrient and it is not needed in the functions of a healthy body; therefore, deficiencies do not exist.

Interactions

Interactions with Supplements, Foods, & Other Compounds

At the time of writing, there were no well-known supplement or food interactions with this supplement.

Interactions with Medicines

As of the last update, we found no reported interactions between this supplement and medicines. It is possible that unknown interactions exist. If you take medication, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.

The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a supplement with your doctor or pharmacist.

Side Effects

Side Effects

DMSO frequently causes a garlic-like body odor and taste in the mouth. Other reported side effects include stomach upset, sensitivity to light, visual disturbances, and headache. Skin irritation can develop at the site where DMSO is applied topically. Only highly purified, properly diluted DMSO should be used and the skin site and applying hand should be thoroughly cleaned before application, because the solvent properties of DMSO allow contaminants to be absorbed through the skin and transported into the bloodstream. Improperly diluted DMSO can also burn the skin. Check with a healthcare professional for appropriate use.

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  How It Works

Health Information Library

What helps, active substance, contraindications

Publication date: 06/15/2023

THERE ARE CONTRAINDICATIONS. POSSIBLE SIDE EFFECTS. A SPECIALIST’S CONSULTATION IS NECESSARY.Pain in the jointsPain in the joints and musclesInflammation of the jointsFor joints and ligaments

3 All authors

Article content

• Dolobene: composition
• Dolobene: contraindications
• Dolobene or Heparin ointment: which is better?
• Dolobene or Diclofenac: which is better?
• Dolobene or Voltaren: which is better?
• Dolgit or Dolobene: which is better?
• Dolobene or Fastum gel: which is better?
• Dolobene or Traumeel: which is better?
• Summary
• Ask an expert on the topic of the article

I wonder if there is a person on earth who has escaped such an injury as a bruise? We think not. ..

Bruises are characterized by mechanical damage without breaking the integrity of the skin. They are accompanied by pain, swelling and bruising. All these symptoms occur due to vascular damage and activation of the inflammation process. As a rule, bruises are not dangerous and pass at home in a week. But in case of an injury to the head or internal organs, it is imperative to see a doctor.

At home, Dolobene helps to cope with the consequences of bruises. The pharmacist talks about its composition and contraindications and compares it with other means: Heparin ointment, Diclofenac, Voltaren, Dolgit, Fastum gel and Traumeel.

Dolobene: Composition

Dolobene is a multicomponent gel for external use. The composition of Dolobene includes not one active ingredient, but three:

• Sodium heparin has anti-inflammatory, regenerating and antithrombotic effects.
• Dexpanthenol – in the skin turns into vitamin B5 (pantothenic acid) and improves the processes of regeneration and repair of damaged tissues.
• Dimethyl sulfoxide 90% solution (DMSO) – has a local analgesic, decongestant and anti-inflammatory effect. It penetrates well through the skin, mucous membranes, improves microcirculation in tissues and increases the permeability of biological membranes for drugs.

The assortment of modern pharmacies has taught visitors that the same medicine can be in different dosage forms. But the drug Dolobene gel is available in only one form, you should not look for ointment, cream or tablets in Dolobene pharmacies.

All products Dolobene

5 reviews

Dolobene: contraindications

Dolobene should not be used during pregnancy, as there are no studies on the use of the drug in such patients. In addition, the gel is contraindicated in the following cases:

• hypersensitivity to drug components;
• open skin lesions;
• severe diseases of the liver and kidneys;
• serious diseases of the heart and blood vessels;
• bronchial asthma;
• children under 5 years of age;
• lactation.

Dolobene or Heparin ointment: which is better?

Heparin ointment also contains three active ingredients: sodium heparin, benzocaine, benzyl nicotinate. The common component with Dolobene in the ointment is only Heparin sodium.

Dolobene – what helps? Gel is prescribed for bruises, closed injuries and inflammation of soft tissues, tendons and joints. Dolobene helps with bruises, swelling and pain in acute neuralgia.

Heparin ointment has different indications due to a different composition. The ointment is used for inflammatory diseases of the veins (thrombophlebitis, periphlebitis, phlebitis after injections, hemorrhoids), as well as for superficial mastitis, infiltrates, edema, injuries and bruises.

Dolobene contains 500 IU/g of heparin and Heparin Ointment contains 100 IU/g. According to the instructions in the RLS, the penetration of heparin through healthy skin is dose-dependent and has been confirmed for doses of 300 IU/g. The effectiveness of heparin in Doloben is higher due to the dosage and content of the “conductor” DMSO in the gel composition.

Heparin ointment has its own advantages: it has a pronounced analgesic effect due to the local anesthetic benzocaine. In addition, it can be used for bruises and bruises in children older than 1 year, unlike Dolobene, which is used only after 5 years.

Dolobene or Diclofenac: which is better?

Diclofenac is the “gold standard” of non-steroidal anti-inflammatory drugs (NSAIDs). The active substance of the same name comes in various forms for external use: gel, ointment, cream, transdermal patch. Diclofenac has a strong anti-inflammatory effect, so it is prescribed for diseases of the spine and joints, as well as to relieve pain and inflammation due to sprains, bruises and injuries.

The drugs act differently, for example, Dolobene will not help with osteochondrosis, it has an insufficient anti-inflammatory and analgesic effect. But swelling and hematoma after a bruise will pass with it faster than with Diclofenac ointment or gel.

All products Diclofenac

20 reviews

Dolobene or Voltaren: which is better?

Voltaren is an original drug with the active ingredient diclofenac. The above information about Diclofenac is fully applicable to it: Voltaren topical agents relieve inflammation and pain well, and Dolobene improves microcirculation, relieves swelling, dissolves blood clots and promotes tissue repair.

Voltaren topical preparations can only be used in children from 12 years of age. For pregnant women, they can be prescribed by a doctor only up to the 20th week of pregnancy.

All products Voltaren Emulgel

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Dolgit or Dolobene: which is better?

Dolgit contains another non-steroidal anti-inflammatory drug, ibuprofen. Dolgit is available in the form of a gel and cream. The drug is approved for use in children from 14 years of age, pregnant women are prescribed only Dolgit gel in the I and II trimester according to indications and under the supervision of a doctor, the cream is contraindicated throughout pregnancy.

The property of ibuprofen to reduce pain and inflammation is used to treat arthritis, osteoarthritis, sciatica, etc. Like Dolobene, Dolgit relieves pain after injuries and bruises. But it does not affect the restoration of tissues and the improvement of blood circulation in the damaged area.

All products Dolgit

20 reviews

Dolobene or Fastum gel: which is better?

The next representative of NSAIDs for the treatment of pain and inflammation is Fastum gel with the active ingredient ketoprofen. Like Dolobene, it has one dosage form in the form of a gel for external use.

Ketoprofen has the most powerful analgesic effect among NSAIDs, so it is used for severe pain as a result of injuries, including bruises, sprains and muscles, as well as for lumbago and rheumatic pains. The gel is contraindicated in pregnancy in the third trimester and in children under 12 years of age.

Fastum causes photosensitivity. When using it, you should protect the skin from the sun during treatment and for another two weeks after it. With mild or moderate pain, bruising and swelling, it is better to use Dolobene.

All products Fastum gel

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Dolobene or Traumeel: which is better?

Traumeel S is a homeopathic remedy. Active substances are 12 vegetable and 2 mineral components. Their combination acts in synergy and has an anti-inflammatory and analgesic effect.

Traumeel S is available as an ointment and is approved for use by adults and children from 3 years of age. The ointment eliminates swelling, pain and inflammation in case of damage to muscles, tendons, ligaments; after operations; with bruises, sprains, dislocations.

The ointment can be used in pregnant women if the expected benefit to the mother outweighs the potential risk to the fetus and child. Contraindications for Traumeel S are autoimmune diseases and tuberculosis.

Traumeel S ointment and Dolobene gel are available without a doctor’s prescription. The patient can consult a pharmacy or his doctor and purchase one of the drugs based on his preferences.

All products Traumeel

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Summary

• Dolobene is a multicomponent gel for external use. It contains sodium heparin, dexpanthenol and dimethyl sulfoxide. The gel is prescribed for bruises, closed injuries and inflammation of soft tissues, tendons and joints. Dolobene helps with bruises, swelling and pain in acute neuralgia.
• Dolobene should not be used during pregnancy, as there are no studies on the use of the drug in such patients.
• Heparin ointment also contains three active ingredients: sodium heparin, benzocaine, benzyl nicotinate. The ointment is used for inflammatory diseases of the veins (thrombophlebitis, periphlebitis, phlebitis after injections, hemorrhoids), as well as for superficial mastitis, infiltrates, edema, injuries and bruises.
• Voltaren with Diclofenac, as representatives of NSAIDs, act differently. For example, Dolobene will not help with osteochondrosis, it has an insufficient anti-inflammatory and analgesic effect. But swelling and hematoma after a bruise will pass with it faster than with an ointment or gel with diclofenac.
• Dolgit relieves pain after injuries and bruises. But it does not affect the restoration of tissues and the improvement of blood circulation in the damaged area.
• Ketoprofen has the most powerful analgesic effect among NSAIDs, so it is used for severe pain as a result of trauma, including bruises, sprains and muscles, as well as for lumbago and rheumatic pains.
• Traumeel S is a homeopathic remedy. The ointment eliminates swelling, pain and inflammation in case of damage to muscles, tendons, ligaments; after operations; with bruises, sprains, dislocations. The patient can consult a pharmacy or his doctor and purchase one of the drugs based on his preferences.

Ask an expert about the topic of the article

Still have questions? Ask them in the comments below and our experts will answer you. There you can also share your experience with other Megatips readers.

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Theraflex Chondrocream forte cream 50g with free home delivery from VkusVill

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wadded shade color with the smell of dimethyl sulfoxide.

Theraflex Chondrocream forte cream 50g / Pharmacy

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from the partner “Apteka Dialog Sever”

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Description

Cream from light yellow with a greenish tint to yellow with a greenish tint, with a smell of dimethyl sulfoxide.

Indications for use

The drug is recommended for use as part of complex therapy for degenerative-dystrophic diseases of the musculoskeletal system: osteoarthritis, osteochondrosis of the spine, and other joint diseases accompanied by pain.