How does DMSO work for arthritis. What are the potential benefits and risks of using DMSO. Is DMSO FDA-approved for arthritis treatment. What are the medical applications of DMSO. How should DMSO be used safely.

Understanding DMSO: Origins and Properties

Dimethyl sulfoxide (DMSO) is a colorless, odorless liquid that originates as a byproduct of paper manufacturing. Initially utilized primarily as an industrial solvent, DMSO gained attention in the medical field during the 1960s when scientists discovered its unique ability to penetrate biological membranes rapidly. This property allows DMSO to facilitate the absorption of topical medications through the skin, making it a potentially valuable tool in drug delivery systems.

Beyond its role as a solvent and penetration enhancer, DMSO has been noted for its potential anti-inflammatory and analgesic properties. These characteristics have led to growing interest in DMSO as a potential treatment for various conditions, including arthritis.

Key Properties of DMSO

• High penetration ability through organic membranes
• Potential anti-inflammatory effects
• Possible pain-reducing properties
• Acts as a carrier for other substances

DMSO and Arthritis: Examining the Claims

Despite gaining commercial popularity as a potential arthritis treatment, it’s crucial to understand that the Food and Drug Administration (FDA) has not approved DMSO or any DMSO-derived medications for treating arthritis. The only FDA-approved use for DMSO is in the treatment of interstitial cystitis, a chronic bladder condition.

Why has DMSO gained attention for arthritis treatment? The substance’s purported anti-inflammatory properties have led some to claim that it may help reduce pain and inflammation associated with arthritis. However, it’s important to note that current evidence supporting these claims is largely anecdotal rather than based on rigorous scientific studies.

Current Status of DMSO for Arthritis

• Not FDA-approved for arthritis treatment
• Claims based primarily on anecdotal evidence
• Lacks substantial scientific backing for arthritis use

Potential Risks and Side Effects of DMSO Use

A comprehensive review of 109 studies reporting adverse effects of DMSO in humans revealed that while most negative reactions were either short-term or rare, there are potential risks associated with its use. Understanding these risks is crucial for anyone considering DMSO as a treatment option.

Common Side Effects

• Gastrointestinal symptoms (halitosis, abdominal discomfort, nausea, vomiting, diarrhea)
• Dermatological reactions (rashes, itching, scaling, blistering, pigmentation changes)

Rare Side Effects

• Cardiac reactions (associated with intravenous administration)
• Neurological reactions

Can the administration method affect side effects? Yes, the research indicated that the method of DMSO administration could influence the occurrence of side effects. For instance, cardiac reactions were only observed with intravenous administration, while skin reactions were more common with topical applications.

Is there a correlation between DMSO dosage and side effects? Indeed, the study found a connection between dose size and adverse reactions. Lower doses were associated with no or mild side effects, suggesting that proper dosing is crucial for minimizing risks.

DMSO Interactions with Other Medications

One of the primary concerns with DMSO use is its potential to interact with other medications. Due to its high absorption rate through the skin, DMSO could potentially increase the absorption of other topical medications to dangerous levels. This interaction potential underscores the importance of consulting a healthcare professional before using DMSO, especially for individuals taking other medications.

Precautions When Using DMSO

• Consult a doctor before use, especially if taking other medications
• Avoid combining with other topical treatments unless advised by a healthcare professional
• Be aware of potential increased absorption of other substances

Proper Usage and Administration of DMSO

How should DMSO be used safely? DMSO should only be used under the guidance and prescription of a healthcare professional. The most common and well-studied methods of administration are topical (such as gels or solutions) and intravesical (through the bladder).

Common DMSO Administration Methods

1. Topical application (gels, creams, solutions)
2. Intravesical administration (for bladder conditions)

Are there other methods of DMSO administration? While oral and intravenous methods exist, there is insufficient research to determine their safety and efficacy. These methods should be approached with caution and only under strict medical supervision.

Medical Applications of DMSO: Current and Potential Uses

While DMSO has gained attention for various potential medical applications, it’s crucial to understand its current approved uses and the state of research for other conditions. The only FDA-approved medical use for DMSO is in the treatment of interstitial cystitis, a chronic bladder condition characterized by pain and pressure in the bladder area.

What other conditions are being researched for DMSO treatment? While scientific evidence is still limited, researchers are exploring DMSO’s potential in several areas:

• Pain management
• Inflammatory conditions
• Wound healing
• Certain types of cancer (as an adjunct to treatment)

However, it’s important to note that these potential applications require further rigorous scientific study before any conclusions can be drawn about their safety and efficacy.

DMSO and Cancer: A Complex Relationship

The relationship between DMSO and cancer treatment is complex and still under investigation. Some studies have shown potential benefits, while others have raised concerns about interactions with certain chemotherapy drugs.

Can DMSO interfere with chemotherapy? A 2014 study indicated that DMSO might interfere with platinum-based chemotherapy drugs such as cisplatin, carboplatin, and oxaliplatin. This interaction could potentially reduce the effectiveness of these treatments.

Are there any positive findings regarding DMSO and cancer? Interestingly, a more recent 2020 study suggested that DMSO might have anti-cancer properties, potentially inhibiting the growth of cancer cells and promoting their death. However, these findings are preliminary and require further research to confirm their clinical relevance.

Has DMSO been approved for any cancer treatments? The FDA has approved a combination of trametinib and dimethyl sulfoxide (trametinib dimethyl sulfoxide) for treating certain types of cancer, including anaplastic thyroid cancer, melanoma, and non-small cell lung cancer. However, this treatment is only recommended for patients who meet specific criteria.

DMSO in Cancer Research: Key Points

• Potential interference with certain chemotherapy drugs
• Preliminary evidence of possible anti-cancer properties
• FDA-approved combination treatment for specific cancers under certain conditions
• Need for further research to clarify benefits and risks

The Future of DMSO Research and Potential Applications

While DMSO has been the subject of numerous studies and has gained popularity in certain circles, its full potential in medical applications remains to be fully explored. The unique properties of DMSO, particularly its ability to penetrate biological membranes and potentially reduce inflammation, continue to intrigue researchers and clinicians alike.

What areas of DMSO research show promise? Several fields of study are actively investigating DMSO’s potential:

• Drug delivery systems: Utilizing DMSO’s penetration-enhancing properties to improve the efficacy of topical medications
• Neuroprotection: Exploring DMSO’s potential to protect nerve cells from damage
• Cryopreservation: Using DMSO as a cryoprotectant in the freezing and storage of biological materials
• Anti-inflammatory applications: Further investigating DMSO’s potential in treating various inflammatory conditions

How might future research impact DMSO’s medical use? As more rigorous studies are conducted, we may gain a clearer understanding of DMSO’s efficacy and safety profile for various conditions. This could potentially lead to new FDA-approved applications or, conversely, further restrictions on its use.

Challenges in DMSO Research

1. Standardizing concentrations and formulations for consistent results
2. Addressing potential long-term effects of DMSO use
3. Clarifying interactions with other medications and treatments
4. Developing targeted delivery methods to maximize benefits while minimizing side effects

As research progresses, it’s crucial for both healthcare providers and patients to stay informed about the latest findings regarding DMSO. This will ensure that any potential benefits can be weighed against known risks, leading to more informed decisions about its use in medical treatments.

Navigating DMSO Use: Guidelines for Patients and Healthcare Providers

Given the complex nature of DMSO and its current status in medical use, it’s essential for both patients and healthcare providers to approach its use with caution and informed decision-making. Here are some guidelines to consider:

For Patients

• Always consult with a healthcare professional before using DMSO for any condition
• Be wary of over-the-counter DMSO products, as they may not be regulated or safe for medical use
• Report any side effects or unusual reactions to your healthcare provider immediately
• Do not use DMSO as a substitute for FDA-approved treatments without medical supervision
• Be honest about any other medications or supplements you’re taking to avoid potential interactions

For Healthcare Providers

• Stay informed about the latest research on DMSO and its potential applications
• Consider DMSO’s potential interactions with other medications when prescribing
• Monitor patients closely for any adverse reactions when using DMSO
• Educate patients about the limitations of current research and the importance of using DMSO only as directed
• Report any significant findings or adverse events to appropriate regulatory bodies to contribute to the overall understanding of DMSO’s effects

How can patients and healthcare providers work together to ensure safe DMSO use? Open communication is key. Patients should feel comfortable discussing their interest in DMSO with their healthcare providers, and providers should be prepared to offer evidence-based advice on its potential benefits and risks.

Alternative Treatments for Arthritis: Exploring Options Beyond DMSO

While DMSO has gained attention as a potential arthritis treatment, it’s important to remember that there are numerous FDA-approved and well-studied options available for managing arthritis symptoms. For those seeking alternatives to traditional arthritis treatments, several options exist that have more substantial scientific backing than DMSO.

FDA-Approved Arthritis Treatments

• Nonsteroidal anti-inflammatory drugs (NSAIDs)
• Disease-modifying antirheumatic drugs (DMARDs)
• Corticosteroids
• Biologic response modifiers
• Targeted synthetic DMARDs

Complementary and Alternative Therapies

In addition to conventional treatments, some people find relief from arthritis symptoms through complementary therapies. While these should not replace prescribed treatments, they may offer additional benefits when used in conjunction with standard care:

• Acupuncture
• Massage therapy
• Yoga and tai chi
• Dietary supplements (e.g., glucosamine, chondroitin)
• Heat and cold therapy
• Mind-body techniques (e.g., meditation, relaxation exercises)

What factors should be considered when choosing arthritis treatments? The choice of treatment should be based on several factors, including the type and severity of arthritis, overall health status, potential side effects, and individual preferences. A healthcare provider can help create a personalized treatment plan that addresses these factors.

Lifestyle Modifications for Arthritis Management

Beyond medical treatments, certain lifestyle changes can significantly impact arthritis symptoms and overall quality of life:

1. Regular exercise and physical activity
2. Maintaining a healthy weight
3. Adopting an anti-inflammatory diet
4. Using assistive devices to reduce joint stress
5. Getting adequate rest and managing stress

By exploring these various options and working closely with healthcare providers, individuals with arthritis can develop comprehensive management strategies that go beyond relying on unproven treatments like DMSO.

DMSO benefits, uses, risks, and more

While there are many arthritis treatments available, not all medications that companies market to treat the condition have approval for that purpose. One of these is dimethyl sulfoxide (DMSO).

DMSO is a clear, odorless liquid that easily penetrates the skin and other organic membranes.

It is gaining commercial traction as a potential treatment for arthritis symptoms, mostly due to its ability to reduce pain and inflammation. However, it does not have approval as an arthritis treatment.

Despite anecdotal claims of its benefits, using DMSO for arthritis, especially as an over-the-counter treatment, could be dangerous.

Read more to learn about the medical uses for DMSO, how it works, its risks and benefits, and more.

DMSO is a byproduct of the paper-making process. Originally, manufacturers used it primarily as an industrial solvent.

In the 1960s, scientists realized that DMSO could act as a way to administer topical medications. Because biological membranes can rapidly absorb DMSO, the substance can help the skin absorb medicines. It may also have pain and inflammation-reducing properties.

Probably due to its purported anti-inflammatory properties, DMSO has gained some commercial popularity as a treatment for arthritis. Some people claim that DMSO may help reduce pain and inflammation associated with the condition.

However, the Food and Drug Administration (FDA) has not approved DMSO, or any medication that includes DMSO-derived ingredients, to treat arthritis. It only has FDA approval to treat interstitial cystitis, a condition causing bladder pain.

While some research on DMSO for arthritis management may warrant further investigation, the current evidence is anecdotal rather than scientific.

With this in mind, people interested in trying DMSO for arthritis should speak with a doctor first.

In a 2018 review, researchers looked at 109 studies that reported harmful side effects of DMSO in humans. They found that most negative reactions were either short term or rare.

Some of the most common reported adverse reactions were gastrointestinal symptoms, such as halitosis, abdominal aches, stomach cramps, nausea, vomiting, and diarrhea. Other common reactions included dermatological skin reactions, such as rashes, itching, scaling, blistering, and pigmentation increases. There were also rare side effects that included cardiac and neurological reactions.

Additionally, the research indicated that side effects may have links to its administration method. For example, cardiac reactions only occurred when healthcare professionals administered DMSO intravenously, and skin reactions were more likely to develop following topical applications.

Furthermore, researchers found a connection between the dose size and reactions. People who took low doses reported no or mild side effects.

DMSO may also negatively interact with other medications. For example, because DMSO easily absorbs into the skin, using it with other topical medications could dangerously increase the amount of medication the body receives.

People interested in using DMSO for arthritis should contact a doctor before trying it or starting any new medication.

People should only use DMSO when a doctor prescribes it. The most common ways of use are topical, such as a gel or other solution, or intravesically, which involves going through the bladder.

Other methods include oral and intravenous. However, there is not enough research to determine their safety.

DMSO is also in common use as a chemical solvent in scientific and industrial communities. Medically, the only FDA-approved use for DMSO is as a treatment for interstitial cystitis, a chronic and often painful bladder condition.

There is still insufficient scientific evidence proving DMSO is both a safe and effective alternative treatment for these and other conditions.

Cancer and DMSO

While some people may experience relief from certain chemotherapy side effects, such as skin and tissue damage, using DMSO as an alternative treatment for cancer can carry risks. For example, a 2014 study explains how DMSO can interfere with chemotherapy drugs such as cisplatin, carboplatin, and oxaliplatin.

Conversely, a more recent 2020 study shows DMSO may prevent the growth of and encourage the death of cancer cells.

Furthermore, the FDA has approved trametinib dimethyl sulfoxide — a combination of trametinib and dimethyl sulfoxide — for treating anaplastic thyroid cancer, melanoma, and nonsmall cell lung cancer. However, doctors only recommend the treatment if a person and the cancer they have meet certain criteria.

At present, DMSO only has FDA approval to treat interstitial cystitis. While there is some anecdotal evidence that DMSO may alleviate the pain and inflammation associated with arthritis, there is no scientific evidence proving its efficacy.

A person interested in using DMSO for arthritis should contact a doctor.

DMSO benefits, uses, risks, and more

While there are many arthritis treatments available, not all medications that companies market to treat the condition have approval for that purpose. One of these is dimethyl sulfoxide (DMSO).

DMSO is a clear, odorless liquid that easily penetrates the skin and other organic membranes.

It is gaining commercial traction as a potential treatment for arthritis symptoms, mostly due to its ability to reduce pain and inflammation. However, it does not have approval as an arthritis treatment.

Despite anecdotal claims of its benefits, using DMSO for arthritis, especially as an over-the-counter treatment, could be dangerous.

Read more to learn about the medical uses for DMSO, how it works, its risks and benefits, and more.

DMSO is a byproduct of the paper-making process. Originally, manufacturers used it primarily as an industrial solvent.

In the 1960s, scientists realized that DMSO could act as a way to administer topical medications. Because biological membranes can rapidly absorb DMSO, the substance can help the skin absorb medicines. It may also have pain and inflammation-reducing properties.

Probably due to its purported anti-inflammatory properties, DMSO has gained some commercial popularity as a treatment for arthritis. Some people claim that DMSO may help reduce pain and inflammation associated with the condition.

However, the Food and Drug Administration (FDA) has not approved DMSO, or any medication that includes DMSO-derived ingredients, to treat arthritis. It only has FDA approval to treat interstitial cystitis, a condition causing bladder pain.

While some research on DMSO for arthritis management may warrant further investigation, the current evidence is anecdotal rather than scientific.

With this in mind, people interested in trying DMSO for arthritis should speak with a doctor first.

In a 2018 review, researchers looked at 109 studies that reported harmful side effects of DMSO in humans. They found that most negative reactions were either short term or rare.

Some of the most common reported adverse reactions were gastrointestinal symptoms, such as halitosis, abdominal aches, stomach cramps, nausea, vomiting, and diarrhea. Other common reactions included dermatological skin reactions, such as rashes, itching, scaling, blistering, and pigmentation increases. There were also rare side effects that included cardiac and neurological reactions.

Additionally, the research indicated that side effects may have links to its administration method. For example, cardiac reactions only occurred when healthcare professionals administered DMSO intravenously, and skin reactions were more likely to develop following topical applications.

Furthermore, researchers found a connection between the dose size and reactions. People who took low doses reported no or mild side effects.

DMSO may also negatively interact with other medications. For example, because DMSO easily absorbs into the skin, using it with other topical medications could dangerously increase the amount of medication the body receives.

People interested in using DMSO for arthritis should contact a doctor before trying it or starting any new medication.

People should only use DMSO when a doctor prescribes it. The most common ways of use are topical, such as a gel or other solution, or intravesically, which involves going through the bladder.

Other methods include oral and intravenous. However, there is not enough research to determine their safety.

DMSO is also in common use as a chemical solvent in scientific and industrial communities. Medically, the only FDA-approved use for DMSO is as a treatment for interstitial cystitis, a chronic and often painful bladder condition.

There is still insufficient scientific evidence proving DMSO is both a safe and effective alternative treatment for these and other conditions.

Cancer and DMSO

While some people may experience relief from certain chemotherapy side effects, such as skin and tissue damage, using DMSO as an alternative treatment for cancer can carry risks. For example, a 2014 study explains how DMSO can interfere with chemotherapy drugs such as cisplatin, carboplatin, and oxaliplatin.

Conversely, a more recent 2020 study shows DMSO may prevent the growth of and encourage the death of cancer cells.

Furthermore, the FDA has approved trametinib dimethyl sulfoxide — a combination of trametinib and dimethyl sulfoxide — for treating anaplastic thyroid cancer, melanoma, and nonsmall cell lung cancer. However, doctors only recommend the treatment if a person and the cancer they have meet certain criteria.

At present, DMSO only has FDA approval to treat interstitial cystitis. While there is some anecdotal evidence that DMSO may alleviate the pain and inflammation associated with arthritis, there is no scientific evidence proving its efficacy.

A person interested in using DMSO for arthritis should contact a doctor.

Scientists have found a way to destroy the toxic “eternal chemicals” that flooded the world – Gazeta.Ru

Scientists have found a way to destroy the toxic “eternal chemicals” that flooded the world – Gazeta.Ru | News

August 20, 2022, 19:03

close

100%

Researchers have shown that a mixture of soap and DMSO solvent can break down per- and polyfluoroalkyl compounds (PFAS), known as “timeless chemicals”. Development reported Science .

Two years ago, researchers from the US Environmental Protection Agency placed a sample of PFAS in a common solvent (DMSO) to study toxicity, but the substance began to degrade. The new study builds on this observation. Scientists from Northwestern University studied various mixtures containing DMSO. The mixture of DMSO and sodium hydroxide, a common soap ingredient, showed the greatest effectiveness when heated to boiling point.

This method works with approximately 40% PFAS. Now it has to be tested on large volumes. Those compounds, the destruction of which chemists have studied, are used in fire-fighting foams and the production of non-stick coatings.

PFAS are known as “timeless chemicals” because they can remain in the environment for decades. Recently, they have even been found in rainwater in the Tibetan Plateau in quantities far exceeding safe ones. The new method will cheaply and safely cleanse the planet of potentially toxic and carcinogenic substances.

Subscribe to Gazeta.Ru in News, Zen and Telegram.
To report a bug, highlight the text and press Ctrl+Enter

News

Zen

Telegram

Artur Muradyan

Is it worth vacationing in Turkey and Egypt in the summer of 2023?

About holidays in popular foreign destinations

11:23

Alexander Tikhomirov

How to teach a child financial literacy

Alexander Tikhomirov, Executive Director of SberLife Insurance, on correct pocket spending

18.07.2023, 10:03

Georgy Bovt

Why does Russia need a “grain deal”

Who is pouring water on whose mill in the food exports of the Black Sea region

17.07.2023, 11:06

Alena Solntseva

The Librarian TV Series: Lord of the Battle Reading Rooms

About the new show with Nikita Efremov

16. 07.2023, 16:16

Aram Ter-Ghazaryan

How Internet Cherkizon was destroyed in the “quarrel in the sandbox”

What threatens marketplaces with the new law on online trading

14.07.2023, 11:11

DMSO (dimethyl sulfoxide) in the best quality pharmaceutical premium

DMSO – Universal Solvent (100 ml)

Dimethyl Sulfoxide (DMSO) is a colorless and odorless organic universal solvent used in laboratory and technical applications. Very high purity of 99.9% meets Ph.Eur certification. Depending on the application, it is easily mixed with water in any ratio. It has an amazing amount of good properties and is extremely versatile.

Benefits of using DMSO:

• Pharmaceutical purity according to the European Pharmacopoeia

• Integrated dropper for easy dosing

• TÜV Rheinland tested: 100% EU-compliant

• Filled in break-proof and child-proof HDPE bottle

• is perfect for travel, outdoor or crisis preparedness!

• The original, only from AQUARIUS pro life

Disadvantages compared to other DMSO solutions:

• often no pharmaceutical safety

• No TÜV-tested EU conformity

• Often bottled in fragile glass bottles

• is therefore impractical for travel and outdoor use.

Benefits of using DMSO:

• Pharmaceutical purity according to the European Pharmacopoeia

• Integrated dropper for easy dosing

• TÜV Rheinland tested: 100% EU-compliant

• Filled in break-proof and child-proof HDPE bottle

• is perfect for travel, outdoor or crisis preparedness!

• The original, only from AQUARIUS pro life

Disadvantages compared to other DMSO solutions:

• often no pharmaceutical safety

• No TÜV-tested EU conformity

• Often bottled in fragile glass bottles

• is therefore impractical for travel and outdoor use.

Content:

100ml 99.9% DMSO ultrapure Ph.Eur in HDPE bottle

(CAS no: 67-68-5, EC no: 200-664-3) Taric: 29091990

Storage and shelf life:

Store in a dry place at room temperature, well closed and out of the reach of children!

DMSO becomes crystalline and solid at low temperatures below 18°C, eg during transport or in winter. This is completely normal and harmless. When heated in a warm water bath, it becomes liquid again. Remove residues on fabrics and surfaces immediately with a damp cloth. DMSO is a long-term stable compound and therefore has a very long shelf life.

Areas of use:

Depending on the application, DMSO can be easily mixed with water in any ratio. Dimethyl sulfoxide has an amazing amount of good properties and is extremely versatile, being used in cosmetics, pharmaceuticals, and as a widely used solvent in laboratories and engineering, among others.

Environment protection:

The raw materials for our sustainable packaging and product information sheet come from sustainable forestry (FSC) and are printed in a climate-neutral way. Please recycle them. Our bottles, child-resistant cap and label are made from polyethylene and are recyclable.

Important note:

Use solvents safely! Always read the label and product information before use.

Keep out of reach of children.

“Glass or HDPE bottle – which is better?”.

Many suppliers use amber glass bottles and advertise that they are much safer and better protect the contents from, for example, UV rays or soluble plastic. However, the fact is that this ingredient is not sensitive to either light or UV, and HDPE (High Density Polyethylene) is a legally approved and suitable storage material. Every industrial manufacturer of DMSO produces, bottles and stores it in HDPE cans, drums or containers.

How can quality be improved by pouring into glass bottles?

Conclusion: HDPE is a legal plastic for storing DMSO and does not mix with the filler in any way. Precise drip filling is much easier with our unbreakable HDPE bottle.

That’s why we only use approved HDPE and not glass – for your safety!

Other customers also bought:

In stock!


In stock!


In stock!

Maltesian Mineral Solution

1003

€18.40

CDSplus – Original only from AQUARIUS pro life
✓ Only activates when you need it!✓ CDSplus has a shelf life of 4-5 years if not activated!✓ Tested and safe – 100% EU compliant – made in Germany!✓ Suitable for everyone – optimal for e.