How does raspberry ketone affect hair growth and skin elasticity. Can raspberry ketone stimulate dermal production of insulin-like growth factor-I. What are the effects of topical application of raspberry ketone on mice and humans. Does raspberry ketone cause hair loss or promote hair growth.

The Science Behind Raspberry Ketone and Hair Growth

Raspberry ketone (RK), a compound found in red raspberries, has garnered attention for its potential effects on hair growth and skin elasticity. A study conducted by Harada et al. explored the impact of topical application of raspberry ketone on dermal production of insulin-like growth factor-I (IGF-I) in mice and its effects on hair growth and skin elasticity in humans. The findings suggest that raspberry ketone may have promising benefits for hair growth and skin health.

The Role of Calcitonin Gene-Related Peptide (CGRP)

Calcitonin gene-related peptide (CGRP) plays a crucial role in the mechanism by which raspberry ketone affects hair growth and skin elasticity. How does CGRP contribute to these effects? CGRP is released by sensory neurons upon activation. The study revealed that raspberry ketone, at concentrations higher than 1 microM, significantly increased CGRP release from dorsal root ganglion (DRG) neurons isolated from wild-type mice. This increase was completely reversed by capsazepine, an inhibitor of vanilloid receptor-1 activation.

Raspberry Ketone’s Impact on Dermal IGF-I Production

The research conducted by Harada et al. demonstrated that topical application of 0.01% raspberry ketone increased dermal IGF-I levels in wild-type mice 30 minutes after application. Why is this significant? IGF-I, or insulin-like growth factor-I, is known to play a vital role in hair growth and skin health. The increase in dermal IGF-I levels suggests that raspberry ketone may stimulate the production of this important growth factor.

Comparison with CGRP-Knockout Mice

Interestingly, the increase in dermal IGF-I levels was not observed in CGRP-knockout mice. This finding underscores the importance of CGRP in mediating the effects of raspberry ketone on IGF-I production. How does this information contribute to our understanding of raspberry ketone’s mechanism of action? It suggests that raspberry ketone’s effects on hair growth and skin elasticity are likely mediated through the activation of sensory neurons and subsequent release of CGRP.

Effects of Raspberry Ketone on Hair Growth in Mice

The study revealed promising results regarding the effects of raspberry ketone on hair growth in mice. Topical application of 0.01% raspberry ketone increased immunohistochemical expression of IGF-I at dermal papillae in hair follicles. What does this mean for hair growth? The dermal papilla is a critical component of the hair follicle, and increased IGF-I expression in this area suggests a stimulatory effect on hair growth.

Promoting Hair Re-growth

Perhaps the most exciting finding was that topical application of 0.01% raspberry ketone promoted hair re-growth in wild-type mice at 4 weeks after application. How significant is this result? It provides strong evidence that raspberry ketone may have potential as a hair growth stimulant, at least in mice models.

Human Studies: Raspberry Ketone’s Effects on Hair Growth and Skin Elasticity

The researchers also conducted human studies to investigate the effects of raspberry ketone on hair growth and skin elasticity. When applied topically to the scalp and facial skin, 0.01% raspberry ketone showed promising results. How effective was raspberry ketone in promoting hair growth in humans? The study reported that raspberry ketone promoted hair growth in 50% of humans with alopecia (n=10) at 5 months after application.

Improvements in Skin Elasticity

In addition to its effects on hair growth, raspberry ketone also demonstrated benefits for skin elasticity. The study found that topical application of 0.01% raspberry ketone increased cheek skin elasticity at 2 weeks after application in 5 females (p<0.04). How does this contribute to our understanding of raspberry ketone’s potential cosmetic applications? It suggests that raspberry ketone may have multiple benefits for skin health, potentially improving both hair growth and skin elasticity.

Comparing Raspberry Ketone to Other Compounds

The researchers noted that raspberry ketone has a structure similar to that of capsaicin, a compound known to increase facial skin elasticity and promote hair growth through increased dermal IGF-I production. How does this structural similarity inform our understanding of raspberry ketone’s effects? It suggests that raspberry ketone may work through similar mechanisms as capsaicin, activating sensory neurons and stimulating IGF-I production.

Potential Advantages of Raspberry Ketone

While capsaicin has shown promise in promoting hair growth and skin elasticity, it can cause irritation in some individuals due to its pungent nature. How might raspberry ketone compare in this regard? As a naturally occurring compound in raspberries, raspberry ketone may potentially offer similar benefits with less likelihood of irritation, although further research is needed to confirm this hypothesis.

Mechanism of Action: How Raspberry Ketone Stimulates Hair Growth

Based on the findings of this study, the researchers proposed a mechanism by which raspberry ketone promotes hair growth and increases skin elasticity. How does raspberry ketone exert its effects? The proposed mechanism involves the following steps:

1. Raspberry ketone activates sensory neurons
2. Activated neurons release calcitonin gene-related peptide (CGRP)
3. CGRP stimulates dermal production of insulin-like growth factor-I (IGF-I)
4. Increased IGF-I levels in the dermal papillae promote hair growth
5. Elevated IGF-I levels also contribute to improved skin elasticity

This proposed mechanism provides a plausible explanation for the observed effects of raspberry ketone on hair growth and skin elasticity. However, it’s important to note that further research is needed to fully elucidate the precise molecular pathways involved.

Potential Applications and Future Research Directions

The findings of this study open up exciting possibilities for the use of raspberry ketone in hair care and skin care products. What potential applications might emerge from this research? Some possibilities include:

• Development of topical treatments for hair loss
• Incorporation of raspberry ketone into anti-aging skin care formulations
• Creation of natural alternatives to synthetic hair growth stimulants
• Exploration of raspberry ketone’s effects on other aspects of skin health

Future research directions may include larger-scale human trials to confirm the efficacy and safety of raspberry ketone for hair growth and skin elasticity. Additionally, studies investigating the optimal concentration and formulation of raspberry ketone for topical application could help maximize its potential benefits.

Addressing Safety Concerns

While the study reported promising results, it’s important to address potential safety concerns. Are there any known side effects or contraindications for topical use of raspberry ketone? The study did not report any adverse effects, but as with any new treatment, long-term safety studies and larger clinical trials would be necessary to establish a comprehensive safety profile.

Raspberry Ketone vs. Other Hair Growth Treatments

How does raspberry ketone compare to other established treatments for hair loss and skin aging? While this study provides promising initial results, it’s important to consider raspberry ketone in the context of existing treatments. Let’s compare raspberry ketone to some common hair growth treatments:

Minoxidil

Minoxidil is a widely used topical treatment for hair loss. How does raspberry ketone compare to minoxidil? While both compounds appear to promote hair growth, they likely work through different mechanisms. Minoxidil is thought to increase blood flow to the scalp and prolong the anagen (growth) phase of hair follicles. Raspberry ketone, on the other hand, appears to work by stimulating IGF-I production. Further research is needed to directly compare their efficacy.

Finasteride

Finasteride is an oral medication used to treat male pattern baldness. Unlike raspberry ketone, finasteride works by inhibiting the conversion of testosterone to dihydrotestosterone (DHT), a hormone linked to hair loss. Can raspberry ketone offer an alternative to finasteride? While raspberry ketone’s topical application may be appealing to those who prefer to avoid oral medications, more research is needed to compare its long-term efficacy to that of finasteride.

Natural Alternatives

How does raspberry ketone compare to other natural hair growth remedies? Many natural treatments, such as saw palmetto and pumpkin seed oil, have shown promise in promoting hair growth. Raspberry ketone’s mechanism of action through IGF-I stimulation sets it apart from many of these alternatives. However, comparative studies would be necessary to determine its relative efficacy.

Integrating Raspberry Ketone into Hair Care Routines

Given the potential benefits of raspberry ketone for hair growth and skin elasticity, how might it be incorporated into existing hair care routines? While more research is needed to establish optimal usage guidelines, here are some potential ways raspberry ketone could be integrated:

• As a pre-shampoo scalp treatment
• In leave-in conditioners or hair serums
• As an ingredient in scalp massage oils
• In combination with other known hair growth-promoting ingredients

It’s important to note that the study used a 0.01% concentration of raspberry ketone. Any products or home remedies should aim to replicate this concentration for potential efficacy. However, individuals should consult with a healthcare professional before starting any new hair growth regimen.

Potential Synergistic Effects

Could raspberry ketone work synergistically with other hair growth treatments? This is an intriguing possibility that warrants further investigation. For example, combining raspberry ketone with ingredients that improve scalp circulation or provide essential nutrients for hair growth could potentially enhance its effects. However, such combinations should be approached cautiously and ideally under the guidance of a dermatologist or trichologist.

Limitations and Considerations of the Study

While the results of this study are promising, it’s important to consider its limitations and areas for further research. What aspects of the study should be taken into account when interpreting its findings?

• Sample size: The human study involved a relatively small number of participants (10 individuals with alopecia and 5 females for skin elasticity measurements). Larger studies would be needed to confirm these results.
• Duration: The hair growth effects in humans were observed after 5 months of application. Longer-term studies would be beneficial to assess the sustainability of these effects.
• Specificity: The study focused on individuals with alopecia. Further research would be needed to determine if raspberry ketone is equally effective for other types of hair loss.
• Mechanism: While the study proposed a mechanism involving CGRP and IGF-I, more detailed molecular studies could help elucidate the precise pathways involved.

These considerations highlight the need for further research to fully understand the potential of raspberry ketone as a hair growth and skin elasticity treatment. Nonetheless, the results provide a promising foundation for future investigations.

The Broader Implications of Raspberry Ketone Research

Beyond its potential applications in hair care and skin care, what broader implications does this research on raspberry ketone have? The study’s findings contribute to our understanding of the complex relationships between sensory neuron activation, growth factor production, and physiological processes like hair growth and skin elasticity. This knowledge could have far-reaching implications:

Insights into Hair Growth Mechanisms

The study’s findings provide valuable insights into the mechanisms of hair growth. How might this knowledge be applied? Understanding the role of sensory neuron activation and IGF-I production in hair growth could potentially lead to the development of new treatments for various forms of hair loss.

Advancements in Skin Care

The observed effects on skin elasticity suggest potential applications in anti-aging skin care. Could raspberry ketone become a new ingredient in wrinkle-reducing formulations? While more research is needed, the study opens up new avenues for investigation in the field of cosmetic dermatology.

Natural Product Research

This study underscores the potential of natural compounds in addressing health and cosmetic concerns. How might this influence future research? It could encourage more investigations into the bioactive compounds found in fruits and other natural sources, potentially leading to the discovery of new therapeutic agents.

In conclusion, while the study by Harada et al. provides exciting initial findings on the effects of raspberry ketone on hair growth and skin elasticity, it’s clear that more research is needed to fully understand its potential. The proposed mechanism involving sensory neuron activation and IGF-I production offers a plausible explanation for the observed effects, but larger, long-term studies in humans will be crucial to confirm these results and establish optimal usage guidelines. As research in this area continues, raspberry ketone may emerge as a promising natural option for those seeking to improve hair growth and skin elasticity.

Effect of topical application of raspberry ketone on dermal production of insulin-like growth factor-I in mice and on hair growth and skin elasticity in humans

Clinical Trial

. 2008 Aug;18(4):335-44.

doi: 10.1016/j.ghir.2008.01.005.

Epub 2008 Mar 5.

Naoaki Harada 
¹
, Kenji Okajima, Noriko Narimatsu, Hiroki Kurihara, Naomi Nakagata

Affiliations

Affiliation

• ¹ Department of Translational Medical Science Research, Nagoya City University Graduate School of Medical Sciences, Kawasumi 1, Mizuho-cho, Mizuho-ku, Nagoya 467-8601, Japan.

• PMID:

  18321745

• DOI:

  10. 1016/j.ghir.2008.01.005

Clinical Trial

Naoaki Harada et al.

Growth Horm IGF Res.

2008 Aug.

. 2008 Aug;18(4):335-44.

doi: 10.1016/j.ghir.2008.01.005.

Epub 2008 Mar 5.

Authors

Naoaki Harada 
¹
, Kenji Okajima, Noriko Narimatsu, Hiroki Kurihara, Naomi Nakagata

Affiliation

• ¹ Department of Translational Medical Science Research, Nagoya City University Graduate School of Medical Sciences, Kawasumi 1, Mizuho-cho, Mizuho-ku, Nagoya 467-8601, Japan.

• PMID:

  18321745

• DOI:

  10. 1016/j.ghir.2008.01.005

Abstract

Sensory neurons release calcitonin gene-related peptide (CGRP) on activation. We recently reported that topical application of capsaicin increases facial skin elasticity and promotes hair growth by increasing dermal insulin-like growth factor-I (IGF-I) production through activation of sensory neurons in mice and humans. Raspberry ketone (RK), a major aromatic compound contained in red raspberries (Rubus idaeus), has a structure similar to that of capsaicin. Thus, it is possible that RK activates sensory neurons, thereby increasing skin elasticity and promoting hair growth by increasing dermal IGF-I production. In the present study, we examined this possibility in mice and humans. RK, at concentrations higher than 1 microM, significantly increased CGRP release from dorsal root ganglion neurons (DRG) isolated from wild-type (WT) mice and this increase was completely reversed by capsazepine, an inhibitor of vanilloid receptor-1 activation. Topical application of 0.01% RK increased dermal IGF-I levels at 30 min after application in WT mice, but not in CGRP-knockout mice. Topical application of 0.01% RK increased immunohistochemical expression of IGF-I at dermal papillae in hair follicles and promoted hair re-growth in WT mice at 4 weeks after the application. When applied topically to the scalp and facial skin, 0.01% RK promoted hair growth in 50.0% of humans with alopecia (n=10) at 5 months after application and increased cheek skin elasticity at 2 weeks after application in 5 females (p<0.04). These observations strongly suggest that RK might increase dermal IGF-I production through sensory neuron activation, thereby promoting hair growth and increasing skin elasticity.

Similar articles

• Administration of capsaicin and isoflavone promotes hair growth by increasing insulin-like growth factor-I production in mice and in humans with alopecia.

  Harada N, Okajima K, Arai M, Kurihara H, Nakagata N.

  Harada N, et al.
  Growth Horm IGF Res. 2007 Oct;17(5):408-15. doi: 10.1016/j.ghir.2007.04.009. Epub 2007 Jun 13.
  Growth Horm IGF Res. 2007.

  PMID: 17569567

• Effects of topical application of alpha-D-glucosylglycerol on dermal levels of insulin-like growth factor-i in mice and on facial skin elasticity in humans.

  Harada N, Zhao J, Kurihara H, Nakagata N, Okajima K.

  Harada N, et al.
  Biosci Biotechnol Biochem. 2010;74(4):759-65. doi: 10.1271/bbb.90797. Epub 2010 Apr 7.
  Biosci Biotechnol Biochem. 2010.

  PMID: 20378988

• Dietary isoflavone increases insulin-like growth factor-I production, thereby promoting hair growth in mice.

  Zhao J, Harada N, Kurihara H, Nakagata N, Okajima K.

  Zhao J, et al.
  J Nutr Biochem. 2011 Mar;22(3):227-33. doi: 10.1016/j.jnutbio.2010.01.008. Epub 2010 Jun 23.
  J Nutr Biochem. 2011.

  PMID: 20576422

• Promotion of insulin-like growth factor-I production by sensory neuron stimulation; molecular mechanism(s) and therapeutic implications.

  Okajima K, Harada N.

  Okajima K, et al.
  Curr Med Chem. 2008;15(29):3095-112. doi: 10.2174/092986708786848604.
  Curr Med Chem. 2008.

  PMID: 19075656

  Review.

• Final report on the safety assessment of capsicum annuum extract, capsicum annuum fruit extract, capsicum annuum resin, capsicum annuum fruit powder, capsicum frutescens fruit, capsicum frutescens fruit extract, capsicum frutescens resin, and capsaicin.

  [No authors listed]

  [No authors listed]
  Int J Toxicol. 2007;26 Suppl 1:3-106. doi: 10.1080/10915810601163939.
  Int J Toxicol. 2007.

  PMID: 17365137

  Review.

See all similar articles

Cited by

• Glucose-Derived Raspberry Ketone Produced via Engineered Escherichia coli Metabolism.

  Masuo S, Saga C, Usui K, Sasakura Y, Kawasaki Y, Takaya N.

  Masuo S, et al.
  Front Bioeng Biotechnol. 2022 Feb 14;10:843843. doi: 10.3389/fbioe.2022.843843. eCollection 2022.
  Front Bioeng Biotechnol. 2022.

  PMID: 35237585
  Free PMC article.

• Potentials of Raspberry Ketone as a Natural Antioxidant.

  Lim SH, Choi CI.

  Lim SH, et al.
  Antioxidants (Basel). 2021 Mar 18;10(3):482. doi: 10.3390/antiox10030482.
  Antioxidants (Basel). 2021.

  PMID: 33803859
  Free PMC article.

• A Systemic Review on Topical Marketed Formulations, Natural Products, and Oral Supplements to Prevent Androgenic Alopecia: A Review.

  Ashique S, Sandhu NK, Haque SN, Koley K.

  Ashique S, et al.
  Nat Prod Bioprospect. 2020 Dec;10(6):345-365. doi: 10.1007/s13659-020-00267-9. Epub 2020 Oct 4.
  Nat Prod Bioprospect. 2020.

  PMID: 33011954
  Free PMC article.

  Review.

• Hepatoprotective activity of raspberry ketone is mediated via inhibition of the NF-κB/TNF-α/caspase axis and mitochondrial apoptosis in chemically induced acute liver injury.

  Fouad D, Badr A, Attia HA.

  Fouad D, et al.
  Toxicol Res (Camb). 2019 Jul 1;8(5):663-676. doi: 10.1039/c9tx00068b. eCollection 2019 Sep 1.
  Toxicol Res (Camb). 2019.

  PMID: 31588343
  Free PMC article.

• Complementary and Alternative Treatments for Alopecia: A Comprehensive Review.

  Hosking AM, Juhasz M, Atanaskova Mesinkovska N.

  Hosking AM, et al.
  Skin Appendage Disord. 2019 Feb;5(2):72-89. doi: 10.1159/000492035. Epub 2018 Aug 21.
  Skin Appendage Disord. 2019.

  PMID: 30815439
  Free PMC article.

  Review.

See all “Cited by” articles

Publication types

MeSH terms

Substances

Can Raspberry Ketones Regrow Your Hair? Detailed Review Of Research

Update 1/12/20. Raspberry ketones (RK) have been a popular weight loss supplement ever since Dr. Oz called them out on his TV show years ago. I’ve already debunked that weight loss scam, but, is it possible they have other benefits? In this review, I’ll show you the research on raspberry ketones and hair growth.  Can they really help with hair loss? This human research is intriguing. As always I’ll show you both sides of the story. Are raspberry ketones the cure for baldness people have been hoping for or is it a scam? Let’s see what we can discover.

Other Hair Growth Supplement Reviews

1. Viviscal Review
2. Viviscal vs. Nutrafol review
3. My Biotin Pro Clinical Review
4. SeroVital Hair Regeneres review
5. Amplixin Review
6. Hair Essentials Review
7. Castor Oil Hair Growth Review
8. Does Creatine Cause Hair Loss?
9. Rosemary Oil for Balding and Hair loss (video)
10. Can Lavender Oil Help Hair Loss? (video)
11. Can Peppermint Oil Regrow Hair? (video)

What Are Raspberry Ketones?

Raspberry ketones are the natural compounds that allow raspberries to smell like raspberries (Rubus idaeus). It’s as simple as that. Taking raspberry ketone supplements -or eating raspberries – will not cause ketosis or benefit those on a ketogenic diet.

As I pointed out in the raspberry ketone review, this stuff does not burn fat or help people lose weight.

Can Raspberry Ketones Grow Hair?

In 2008, researchers in Japan released a paper detailing how raspberry ketones applied topically to the skin could regrow hair and improve the skin’s elasticity on the face. Here’s a video I created to help you understand this study:

These researchers showed a 0.1% solution of raspberry ketones could regrow hair on the heads of people after 5 months of use. If you watched the video, you saw the before and after pictures of the women who went from bald to having very significant and visible hair growth.

Because this study involved both hair growth and skin elasticity, let’s summarize each segment into two different parts.

Hair Growth Research and Results

Basically, here’s the gist of the research:

• 10 men and women (7 men / 3 women) who were experiencing hair loss (alopecia) were randomly given either a raspberry ketone topical solution – or a placebo solution – which they applied to their scalps once a day for 5 months. They ranged in age from 12 to 45 years.
• 5 people used raspberry ketones and 5 used a placebo solution.
• Before and after pictures were taken.

Results: After 5 months, the people who applied raspberry ketones on their scalps had hair growth. The people using the placebo solution did not. In one case (see video), the improvement in hair growth was dramatically better.

Skin Elasticity Research and Results

10 women (about 38 years of age) with hair used either a 0.01% raspberry ketone solution or a placebo solution for 2 weeks.

• 5 women used the RK solution, and 5 used the placebo solution
• The women applied the solutions to their facial cheek area once per day.
• Skin elasticity was tested before and after the treatment

Results. After 2 weeks of use, women who applied raspberry ketones to their facial cheeks were said to have better elasticity in the skin than those who used the placebo solution.

Problems With The Research

• Each of the 2 parts of the study only had 1o people
• The study has not been replicated with larger clinical trials

It’s been many years since this study was published. Why hasn’t anybody tried to duplicate the results? Oddly, in 2011 these researchers did publish a study noting isoflavones promoted hair growth in mice.

This doesn’t make sense. Why did they study the hair growth properties of isoflavones in mice when they’ve already demonstrated raspberry ketones reverse hair loss in people? Why not just continue investigating RK?

To quote the Lost in Space Robot, “That does not compute. ”

It’s because of this research some websites say RK is a “proven remedy” to combat hair loss. But, as I’ve pointed out, some problems need to be addressed.

Raspberry Ketone Hair FAQ

1 How Is It Supposed To Work?

It’s complicated, but the idea is that RK stimulates insulin-like growth factor 1 (IGF-1), which plays a role in collagen production. Collagen is important to both skin and hair. The mouse portion of this study also noted RK increased IGF-1 within 30 minutes of applying it to the skin of mice.

Raspberry ketones are also said to ramp up the production of another compound called calcitonin gene-related peptide (CGRP) from brain cells. Again, it’s complicated.

2 What Brand Of Raspberry Ketones Did They Use?

The raspberry ketones were supplied by Kanebo Cosmetics and were said to be 99.9% pure. Interestingly, when I went to the Kanebo website, I did not see a hair-growth raspberry ketone product for sale. It looks like they don’t make any.

If kanebo does not sell an RK hair product, this also makes me suspect the above study’s findings. Think about it; if Kanebo’s raspberry ketones really did cause hair to grow back, don’t you think they would start selling a hair-growth product?

Here’s Kanebo Cosmetics on Amazon too

3 How Long Does It Take To Work?

Growing hair back will take about 5 months of continued use. Your degree of hair loss might also play a role. For skin tightening/skin elasticity, results were seen in just 2 weeks.

4 How Much Do You Use?

This study used a 0.01% raspberry ketone solution. The solution was applied directly to the scalp 1x per day (between 10 PM-11 PM). I don’t think the time of day matters but I appreciated them telling us this tidbit.

5 Raspberry Ketone Hair Growth Products

When I checked, I did not see any hair growth products containing raspberry ketones. This is weird. If topical raspberry ketones are effective at reversing hair loss, why aren’t there shampoos or hair tonics people can purchase?

6 Why Did They Use Raspberry Ketones?

Previously these researchers noted the chili pepper compound capsaicin, increased IGF-1 levels in mice. It turns out raspberry ketones look like capsaicin.

7 Will Raspberry Ketone Supplements Work?

If you do your own research, you will notice the label of RK supplements probably touting their hair growth abilities. Be skeptical when you see this. No study has demonstrated hair growth with orally-taken supplements. If RK is going to work, it looks like it has to be applied directly to the skin.

If you are going to use a supplement, crack open the contents, mix it with water and apply it to the scalp.

8 Do Any Hair Growth Products Contain RK?

I have not been able to find any. Neither Viviscal nor Nutrafol – the two best-selling anti-balding supplements -contain raspberry ketones.

9 Does It Block DHT?

Many hair loss supplements and shampoos contain ingredients that block DHT, a hormone linked to hair loss. There seems to be no evidence raspberry ketones block the DHT hormone. Rather, it’s supposed to work by increasing IGF1 levels.

How To Make A Raspberry Ketone Hair Growth Tonic

The study we are talking about here used a 0.01% RK solution which was applied directly to the scalp. The problem is, nobody seems to sell something like this.

Fortunately, you can make this yourself if you want to.

To make a 0.01% RK solution, crack open a 500 mg capsule of a raspberry ketone supplement and mix it with 1.3 gallons of water.

As you can see, this is a VERY dilute solution.

The Easy Way: Liquid raspberry ketone products are available. These are weight loss supplements. While RK won’t help with weight loss, these products already come with an eyedropper which makes applying it to the skin easy. These products are not expensive either.

While this method isn’t very “scientific,” I’m not convinced the 0.01% solution is optimal. So, why not just try to do it the easy way until we know more?

Raspberry Ketone Side Effects

When applied to the scalp and facial skin, side effects were not reported. If you are going to biohack this and try to do it yourself, it’s probably best to apply to a small area of the scalp /skin at first to see how you react. Also, avoid getting raspberry ketones into your eyes.

The people in this study applied the RK solution just 1x per day and did some before going to bed (10 PM-11 PM). This might be wise in case the RK solution gets messy.

If raspberry ketones are absorbed through the skin, its possible there may be interactions with medicines. So, if you take any medications, talk to your pharmacist first.

Also, play it safe, and don’t try this if you are pregnant or breastfeeding.

Other Hair Loss Options

Besides Minoxidil, which is proven to grow hair, natural hair loss solutions include:

• • Pumpkin seed oil (taken as a supplement)
  • Viviscal 
  • Essentials Oils: thyme, rosemary, lavender, and cedarwood applied topically to the scalp

Raspberry Ketones And Hair Growth Pro/Con

Here’s a quick Pro and Con to using raspberry ketones for hair growth

Pro	Con
1 study has shown it works	Study has not been replicated
RK is inexpensive	There don’t seem to be any RK hair growth products
No side effects reported	Finding quality RK products may be an issue
Only needs to be used 1x/day
Just need to apply it to scalp.

Can Raspberry Ketones Regrow Your Hair?

Honestly, I’m not sure, and here’s why. A clinical study has shown that raspberry ketones appear to regrow hair in people with alopecia. But, I can’t get past the investigation that was conducted in 2008. Here we are, many years later, and the study still has not been replicated. Why?

Adding to this is the utter lack of raspberry ketone hair growth products.  If it really worked, why can’t I find any anti-hair loss shampoos, hair tonics, creams, etc., containing this stuff? If you try this, let me know what happens.

Heres the RK liquid on Amazon

Any Questions Or Comments?

Articles » Raspberry ketone properties and uses. | World of Soap Boilers

Good day everyone!

Today our article will be devoted to one of the components for cosmetics – this is RASPBERRY KETONE. Let’s talk about him in more detail!

Raspberry ketone (Raspberry ketone) is a natural phenolic compound, which is the main component of the aroma of raspberries, found in its essential oil. The chemical structure of the ketone is similar to that extracted from ginger zingerone (allowing to reduce obesity), as well as capsaicna , a substance found in chili peppers that also has fat burning properties, and synephrine , a substance found in orange peel and known for its properties to reduce fat and eliminate fluid retention. All these substances (including ketone) act on fat cells and cause fat loss through similar mechanisms – as a result of their hormone-dependent splitting.

INCI: 4-(p-hydroxyphenyl)-2-butanone

Synonyms: hydroxyphenylone, frambinone

PROPERTIES:

– Acceleration and stimulation of hair growth, reduction of hair loss.

– Ideal care for the skin around the eyes – restoration of delicate skin, reduction of wrinkles.

-Improve the condition and appearance of oily, porous skin.

-Gives skin elasticity, smoothness, tones and rejuvenates.

– Allows you to eliminate sagging skin, safely dispose of body fat.

APPLICATION:

– creams and gels for the skin around the eyes

– anti-cellulite products: shower gel, body butters, massage tiles.

– gels and masks to enhance the growth of eyebrows and eyelashes

– shampoos, conditioners, hair masks

– anti-hair loss spray

– tonics and sprays to improve skin elasticity.

HOW TO USE:

Raspberry Ketone dissolves in alcohol or by heating oils and emulsifiers.

If you dilute the ketone in oil, then in the future, before using it, it will be necessary to heat it up each time, since the oil with ketone turns into a gel mass.

It is more convenient to dissolve the ketone in alcohol and use a 2% or 10% solution for the manufacture of cosmetics.

Dissolve *2 g of ketone in 98 g of alcohol (2% solution will be obtained)

Dissolve *10 g of ketone in 90 g of alcohol (10% solution).

If you prepare a 10% solution, then 1 drop of this solution per 50 ml of cream = 0.01%.

Dosage example:

0.01% = 1 drop of solution per 50 ml

0.05% = 5 drops of solution per 50 ml

0.1% = 10 drops of solution per 50 ml

1% = 100 drops (1 tsp) solution per 50 ml

DOSAGE

face creams, lotions – 0.01 – 0.1%

hair products – 0.01-0.5%

anti-cellulite cosmetics – up to 1-2%

perfume compositions – 0.5 – 5%.

And in order not to be unfounded, we will give several recipes using raspberry ketone. You will be able to find them in the recipes section in the near future!

Raspberry Ketone, 10g | HomeArt

Raspberry ketone

INCI: 4-(n-hydroxyphenyl)-2-butanone

Appearance – White needles or granules.

Synonyms: oxyphenylone, frambinone

Description: a natural phenolic compound that is the main component of the aroma of red raspberries (Rubus idaeus). In nature, it is found in its essential oil. This chemical structure is similar to zingerone, which is extracted from ginger and has been shown to reduce obesity. In addition, raspberry ketone is similar to capsaicin (a chemical found in hot chili peppers that has fat-burning properties), synephrine (a compound found in orange peel and known to reduce fat and fluid retention), and evodiamine (another fat-burning ingredient). All of these chemicals, including raspberry ketone, interact with fat cells and cause fat loss through similar mechanisms. In plants, raspberry ketone is synthesized from coumaroyl-CoA. The extraction of pure raspberry ketone is typically 1-4 mg/kg raspberries.

Physical:

Appearance: colorless crystals, white crystalline powder

Molecular mass: 164.20

Formula: C10 h22 O2

Density: 1.088 ± 0.06 g/cm3

Refractive index: 1.535 ± 0, 02

Melting point: 83 – 84°C

Boiling point: 161°C

Auto-ignition point: 195°C, may ignite easily if overheated.

Solubility: soluble in alcohol, dipropylene glycol, propylene glycol, oils, slightly soluble in water, insoluble in vaseline oil, isopropyl myristate.

Cosmetic use: Raspberry ketone is chemically similar to capsaicin, a component found in red peppers. But unlike it, it does not irritate the skin, does not cause burning and redness, and can be used even with sensitive skin. It has no documented side effects associated with consumption and may even be more thermogenic than capsaicin.

Raspberry ketones stimulate hormone-dependent fat breakdown in fat cells. As a result, there is a decrease in the volume of subcutaneous adipose tissue, even with a diet high in lipids.

Obesity and cellulite treatment: Japanese scientists have discovered the ability of raspberry ketones to speed up metabolism and allow the body to safely dispose of excess calories and already accumulated fat deposits. The process of fat burning does not affect the muscles, but gives them a beautiful shape, because. in the process of utilization, fat is broken down, which is not only in fat depots on the abdomen and thighs, but also fat accumulated by the body between muscle fibers and internal organs.

Accelerates metabolism by increasing body temperature, both general and local. Increases the production of the main fat-burning hormones – epinephrine and norepinephrine.

Prevents the destruction of fat-burning hormones, allowing them to act in the body permanently. Prevents the stoppage of the work of alpha receptors of fat cells, also stimulating their constant activity. It is the shutdown of the alpha receptors of fat cells that causes the body to accumulate fat, and not expend it on energy production.

One of the main advantages along with fat-burning properties is the elimination of skin laxity. Increases skin tone and elasticity.

In facial cosmetics, it helps to narrow pores, optimizes metabolic processes, and has a rejuvenating effect.

The relevance and value of hair cosmetics is closely related to their ability to have a general strengthening effect on the hair, stimulate its rapid growth and prevent signs of early hair loss.

Properties:

Removes congestion, accelerates the circulation of mucus.

Eliminates sagging skin, speeds up metabolism and allows the body to safely utilize excess calories and already accumulated fat deposits. The process of fat burning does not affect the muscles, but gives them a beautiful shape.

Gives skin smoothness and elasticity, stimulates metabolism, rejuvenates and tones.

Helps cleanse and protect the skin from environmental damage.

Ideal for skin care in the eye area, as it helps to gently restore delicate skin.

Good for oily skin with enlarged pores.

Accelerates hair growth and prevents hair loss.

Application:

– Soap and shower gel with anti-cellulite action

– Soaking washcloths for the same purpose

– Taking raspberry ketone capsules to burn fat before the competition

– Sprays and tonics to combat baldness and improve skin elasticity

– Shampoos and hair masks

– Anti-cellulite creams and gels

– Gels to enhance the growth of eyelashes and eyebrows

– Creams and gels for the skin around the eyes

Recommended dosages:

The cosmetic dosage of adding raspberry ketone to the prescription composition is from min. 0.02% to 5%, or 5% to 10% (in this case, raspberry ketone dissolves exclusively in diethyl phthalate):

• anti-cellulite products (serums, wraps) – up to 1%;
• cosmetics for the skin of the face (including the area around the eyes0 – up to 0.5%;
• anti-baldness products – 0.02%;
• shampoos, other foamy detergents – up to 2%;
• gels to enhance eyelash growth – 0.01%.8 g of alcohol.
• To create 100 g of a 10% Raspberry Ketone solution, it is recommended to dissolve 10 g of this agent in 90 g of alcohol.
• To create 100 g of a 5% raspberry ketone solution, it is recommended to dissolve 2.5 g of this agent in 48 g of alcohol.

Administer in the final phase of the preparation of the cosmetic product.

When introducing raspberry ketone into oils, it is necessary to introduce it at the stage of the fatty phase of preparation (oils + emulsifier) ​​and then heat until completely dissolved.

Application method:

Dissolve in alcohol or in the oil phase when oils and emulsifiers are heated.