Does Valtrex cause diarrhea. What are the common side effects of Valtrex. How does Valtrex work to treat viral infections. When should you start taking Valtrex for best effectiveness. What precautions should be taken while using Valtrex.

Understanding Valtrex: Uses and Mechanism of Action

Valtrex, also known by its generic name valacyclovir, is an antiviral medication used to treat various viral infections. It belongs to a class of drugs called antivirals, which work by interfering with the reproduction of viruses in the body.

How does Valtrex function in the body? Valtrex works by stopping the virus from multiplying and spreading to nearby healthy cells. This mechanism helps to shorten the duration of outbreaks and reduce the severity of symptoms associated with viral infections.

Primary Uses of Valtrex

• Treatment of shingles (herpes zoster)
• Management of cold sores
• Treatment and prevention of genital herpes recurrences

It’s important to note that while Valtrex is effective in managing these conditions, it does not cure shingles, cold sores, or genital herpes. Instead, it helps to accelerate the healing process of sores and alleviates pain and discomfort associated with these viral infections.

Valtrex Dosage and Administration Guidelines

The dosage of Valtrex varies depending on the condition being treated. Healthcare providers determine the appropriate dose based on factors such as the specific viral infection, severity of symptoms, and individual patient characteristics.

Recommended Dosages for Different Conditions

1. Shingles: 1,000 mg taken 3 times daily for 7 days
2. First episode of genital herpes: 1,000 mg twice daily for 10 days
3. Recurrent genital herpes: 500 mg twice daily for 3 days
4. Prevention of genital herpes recurrences: 1,000 mg once daily (or 500 mg once daily for those with 9 or fewer recurrences per year)
5. Cold sores: 2,000 mg at the first sign of symptoms, followed by another 2,000 mg 12 hours later

When should treatment with Valtrex be initiated for optimal results? For shingles and first episodes of genital herpes, treatment should ideally begin within 72 hours of symptom onset. In the case of cold sores, starting treatment at the first sign of symptoms (such as tingling, itching, or burning sensations) yields the best effectiveness.

Potential Side Effects of Valtrex: Addressing Diarrhea Concerns

While Valtrex is generally well-tolerated, like all medications, it can cause side effects in some individuals. One common concern among patients is whether Valtrex causes diarrhea.

Can Valtrex lead to diarrhea as a side effect? While diarrhea is not listed as one of the most common side effects of Valtrex, it has been reported in some patients. However, it’s important to note that the occurrence of diarrhea may vary from person to person and may not necessarily be directly caused by the medication.

Common Side Effects of Valtrex

• Headache
• Nausea
• Abdominal pain
• Dizziness
• Fatigue

If you experience persistent or severe diarrhea while taking Valtrex, it’s advisable to consult your healthcare provider. They can assess whether the symptom is related to the medication or if there may be other underlying causes.

Precautions and Considerations When Using Valtrex

To ensure safe and effective use of Valtrex, there are several precautions and considerations that patients should be aware of.

Important Precautions

• Kidney function: Patients with impaired kidney function may require dose adjustments.
• Hydration: Adequate fluid intake is essential while taking Valtrex to prevent dehydration.
• Drug interactions: Inform your healthcare provider about all medications you’re currently taking.
• Pregnancy and breastfeeding: Discuss the risks and benefits with your doctor if you’re pregnant or nursing.

How should Valtrex be stored and handled? Store Valtrex at room temperature, protected from light and moisture. Keep it out of reach of children and dispose of unused medication properly as directed by your pharmacist.

Valtrex in the Management of Genital Herpes

Valtrex plays a significant role in the management of genital herpes, both in treating active outbreaks and preventing recurrences.

How does Valtrex help in managing genital herpes? By suppressing viral replication, Valtrex can reduce the frequency and severity of genital herpes outbreaks. Additionally, when used as a suppressive therapy, it can lower the risk of transmitting the infection to sexual partners.

Benefits of Valtrex in Genital Herpes Management

• Faster healing of sores during active outbreaks
• Reduction in pain and discomfort associated with outbreaks
• Decreased frequency of recurrences when used as suppressive therapy
• Lowered risk of viral transmission to sexual partners

For individuals with frequent recurrences, daily suppressive therapy with Valtrex can significantly improve quality of life by reducing the burden of outbreaks and associated anxiety.

Valtrex in the Treatment of Shingles (Herpes Zoster)

Shingles, caused by the reactivation of the varicella-zoster virus, can be a painful and debilitating condition. Valtrex offers an effective treatment option for managing shingles outbreaks.

How does Valtrex impact the course of a shingles outbreak? When started early in the course of the infection, Valtrex can help reduce the severity and duration of the shingles rash. It may also help alleviate associated pain and lower the risk of developing post-herpetic neuralgia, a chronic pain condition that can persist after the rash has healed.

Key Points in Shingles Treatment with Valtrex

• Early initiation: Treatment should start within 72 hours of rash onset for best results
• Dosage: 1,000 mg three times daily for 7 days
• Pain management: Valtrex may help reduce acute pain associated with shingles
• Prevention of complications: May lower the risk of post-herpetic neuralgia

While Valtrex is effective in managing shingles, it’s important to note that it does not prevent the development of shingles in individuals who have had chickenpox. For prevention of shingles, vaccination is recommended for eligible individuals.

Valtrex in the Treatment of Cold Sores

Cold sores, caused by the herpes simplex virus, can be bothersome and sometimes painful. Valtrex offers a treatment option that can help manage these outbreaks effectively.

How does Valtrex work to treat cold sores? By inhibiting viral replication, Valtrex can help shorten the duration of a cold sore outbreak and may even prevent the formation of blisters if taken at the earliest signs of an outbreak.

Valtrex Treatment for Cold Sores

• Dosage: 2,000 mg at the first sign of symptoms, followed by another 2,000 mg 12 hours later
• Timing: Most effective when started at the first sign of tingling, itching, or burning
• Duration: Can shorten healing time by 1-2 days compared to no treatment
• Frequency: Can be used to treat each cold sore outbreak as it occurs

For individuals who experience frequent cold sore outbreaks, discussing a suppressive therapy regimen with a healthcare provider might be beneficial.

Drug Interactions and Contraindications of Valtrex

While Valtrex is generally safe and well-tolerated, it’s important to be aware of potential drug interactions and contraindications to ensure safe use of the medication.

What are some important drug interactions to be aware of with Valtrex? Valtrex may interact with certain medications, potentially affecting their effectiveness or increasing the risk of side effects. Some notable interactions include:

• Nephrotoxic drugs: Medications that can affect kidney function may increase the risk of side effects from Valtrex
• Probenecid: May increase blood levels of Valtrex
• Cimetidine: May slightly increase valacyclovir levels in the blood

Contraindications

Valtrex should not be used in certain situations or by certain individuals. These contraindications include:

• Hypersensitivity to valacyclovir, acyclovir, or any components of the formulation
• Severe immunodeficiency (in some cases, as determined by a healthcare provider)
• Severe kidney disease (may require dosage adjustment or alternative treatment)

It’s crucial to provide your healthcare provider with a complete list of all medications, supplements, and medical conditions to ensure safe use of Valtrex and minimize the risk of adverse effects or interactions.

Valtrex – Uses, Side Effects, Interactions

How does this medication work? What will it do for me?

Valacyclovir belongs to the class of medications known as antivirals. It is used to treat a viral infection affecting the skin known as shingles (herpes zoster). It is also used to treat cold sores, and to treat and prevent recurrences of genital herpes. It works by interfering with the way the virus reproduces. Valacyclovir works by stopping the virus from multiplying and spreading to nearby healthy cells.

It does not cure shingles, cold sores, or genital herpes, but it does help the sores to heal more quickly, and it relieves pain and discomfort. When used to prevent recurrences of herpes, it also reduces the risk of transmission (spreading) of the infection to others.

This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

What form(s) does this medication come in?

500 mg
Each blue, film-coated, capsule-shaped tablet (caplet) printed with edible white ink with “VALTREX 500 mg” contains valacyclovir HCl equivalent to 500 mg valacyclovir. Nonmedicinal ingredients: carnauba wax, cellulose, crospovidone, hydroxypropyl methylcellulose, Indigotine Aluminum Lake, magnesium stearate, polyethylene glycol, polysorbate 80, povidone, silicon dioxide, and titanium dioxide.

1,000 mg
Each white, film-coated, capsule-shaped tablet (caplet) printed with edible blue ink with “GX CF2” contains valacyclovir HCl equivalent to 1,000 mg valacyclovir. Nonmedicinal ingredients: carnauba wax, cellulose, crospovidone, hydroxypropyl methylcellulose, magnesium stearate, polyethylene glycol, polysorbate 80, povidone, silicon dioxide, and titanium dioxide.

How should I use this medication?

The recommended adult dose of valacyclovir to treat shingles is 1,000 mg 3 times daily for 7 days. The treatment should be started within 72 hours of the onset of the rash.

To treat the first episode of genital herpes, the dose of valacyclovir is 1,000 mg twice daily for 10 days. Treatment should be started within 72 hours of the onset of symptoms, and ideally within 48 hours for best effectiveness.

To treat recurrent genital herpes, the dose of valacyclovir is 500 mg twice daily for 3 days. The treatment should be started at the first sign or symptom of recurrence.

To prevent recurrences of genital herpes, the recommended dose is 1,000 mg once daily. For people with a history of 9 or fewer recurrences per year, the recommended dosage of valacyclovir is 500 mg orally once daily. This dose helps to reduce the risk of transmitting genital herpes to others.

To treat cold sores, the usual dose of valacyclovir is 2,000 mg at the first sign of symptoms, followed by another 2,000 mg 12 hours later. The treatment should be started at the first sign of a cold sore (tingling, itching, or burning sensations) for best effectiveness.

People with poor kidney function may need lower doses.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way you are using the medication without talking to your doctor.

Valacyclovir can be taken with or without food. If it causes stomach upset, taking it with food may help. Make sure you drink enough water to prevent dehydration while taking valacyclovir.

It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular dosing schedule. If it is almost time for your next dose, skip the missed dose and continue with your usual dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Who should NOT take this medication?

Do not take this medication if you are allergic to valacyclovir, acyclovir, or any ingredients of the medication.

What side effects are possible with this medication?

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

• abdominal pain
• diarrhea
• dizziness
• headache
• increased sensitivity to UV light
• nausea
• skin rash
• vomiting

Although most of the side effects listed below don’t happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• behaviour changes
• confusion
• decreased coordination
• difficulty speaking
• hallucinations
• increased frequency of experiencing infections
• pain in the side between the ribs and hip or kidney area of the back
• signs of anemia caused by red blood cell destruction (e.g., abdominal pain, bloody diarrhea, fatigue, nausea, vomiting, confusion, swelling of hands and feet)
• signs of bleeding (e.g., unusual bruising or bleeding, bleeding gums, unexplained nosebleeds)
• signs of decreased kidney function (e.g., decreased urine production, loss of appetite, nausea)
• tremor
• trouble thinking or making judgements clearly

Stop taking the medication and seek immediate medical attention if any of the following occur:

• seizures
• shortness of breath
• signs of a serious allergic reaction (e. g., abdominal cramps, difficulty breathing, nausea and vomiting, swelling of the face and throat)
• signs of a severe skin reaction (e.g., a rash combined with fever or discomfort, a rash covering a large area of the body, a rash that spreads quickly, blistering, peeling)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.

Are there any other precautions or warnings for this medication?

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Drowsiness/reduced alertness: Valacyclovir may affect the mental or physical abilities needed to drive or operate machinery. Avoid driving, operating machinery, or performing other potentially hazardous tasks until you have determined how you are affected by this medication.

Genital herpes: To reduce the risk of spreading the virus, wash your hands immediately after touching your skin sores. You should avoid intimate contact when live lesions are visible on your skin. The herpes virus can still be spread even when you do not have blisters or sores.

Immunosuppression (weak immune system): People who have a weakened immune system should only use valacyclovir if the benefits outweigh the risks. If you have had an organ transplant, are infected with HIV, or otherwise have a weak immune system, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Kidney disease: Valacyclovir may cause decreased kidney function or kidney failure. People with kidney disease may need a lower dose of this medication. If you have reduced kidney function or kidney disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

If you experience signs of decreased kidney function, such as decreased urine production, nausea, fatigue, or muscle twitches or cramps, contact your doctor as soon as possible.

Safer sex: Valacyclovir, when taken in appropriate doses each day, can reduce the risk of passing genital herpes to sexual partners. It should be used in combination with safer sex practices such as using condoms and dental dams. If you have any questions about practicing safer sex, speak to your doctor.

Systemic infection: The safety and effectiveness of using valacyclovir to treat herpes zoster infection that is inside the body has not been established. This is not an accepted use for this medication.

Pregnancy: Although valacyclovir does not appear to increase the risk of harm to an unborn baby, the safety of valacyclovir use during pregnancy has not been established. This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.

Breast-feeding: This medication passes into breast milk. If you are breast-feeding and are taking valacyclovir, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using this medication have not been established for children.

Seniors: Seniors are more likely to have decreased kidney function than younger adults. A decreased dose of valacyclovir may be required. It is important for seniors to drink enough water while taking this medication, to stay well-hydrated.

What other drugs could interact with this medication?

There may be an interaction between valacyclovir and any of the following:

• cladribine
• clozapine
• foscarnet
• mycophenolate
• tenofovir
• theophyllines (e.g., aminophylline, theophylline)
• tizanidine
• varicella virus vaccine
• zidovudine
• zoster vaccine

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

All material copyright MediResource Inc. 1996 – 2023. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/drug/getdrug/Valtrex

New: Valtrex uses, side effects, interactions and warnings

Valtrex can slow down the growth and spread of viruses like herpes simplex and herpes zoster, but it can come with some serious side effects.

Valtrex side effects | Headache | Nausea | Serious side effects | Kidney failure | Nervous system problems | Warnings | Interactions | How to avoid side effects

If you’ve ever had shingles or cold sores, you know how uncomfortable these infections can be. Valtrex is an antiviral medication that can help relieve symptoms that come from viral infections like shingles or chickenpox. This article gives an overview of drug information including Valtrex side effects, warnings, and drug interactions that you should be aware of before taking the medication.       

What is Valtrex?

Valtrex belongs to a group of medications called antivirals that work by slowing down the growth and spread of viruses like the herpes simplex, herpes zoster, and varicella-zoster viruses. Valtrex is the brand name for valacyclovir hydrochloride. The brand and generic versions of the medication are chemically the same, work the same way, and are equally effective at treating herpes virus infections.

Herpes virus infections include cold sores, genital herpes, shingles, and chickenpox. Valtrex can’t cure herpes infections, but it can treat symptoms like herpes sores and blisters. Valtrex is not an over-the-counter medication, so if you have a herpes infection, you’ll need a prescription.   

It can take up to seven to 10 days for Valtrex to start working for some people, while others may feel relief from their symptoms after a day or two. The amount of time it takes your symptoms to go away will depend on your age, the severity of your symptoms, and your metabolism.

Valtrex for cold sores

Many people wonder whether Valtrex will stop cold sores from forming. Valtrex should be taken at the first signs of a cold sore (tingling, itching, burning) to prevent them from worsening and keep other cold sores from developing. However, it is not a cure for cold sores. It only treats them as a symptom of a viral infection.

Valtrex for genital herpes

Even if you’re taking Valtrex, it’s still possible to have an outbreak. If you’re taking Valtrex for recurrent genital herpes and have an outbreak, it’s important to avoid sexual contact with your partner to keep the virus from spreading to them. Even if you’re not experiencing an outbreak, using condoms is a good idea to prevent transmission.  

Also, if you’re wondering if your uninfected partner can take Valtrex to avoid becoming affected, the answer is no. Someone without herpes simplex virus shouldn’t take medication for something they don’t have. This could cause serious side effects or health problems. 

Common side effects of Valtrex

Taking Valtrex may cause possible side effects, such as:   

• Headache 
• Nausea
• Stomach pain or abdominal pain 
• Dizziness
• Vomiting 
• Weight gain
• Irritability 
• Tiredness
• Trouble sleeping
• Trouble concentrating
• Loss of appetite
• Skin rash
• Bleeding gums
• Sore throat 
• Diarrhea  
• Joint pain 

Headache

Headache is a common side effect of Valtrex. If you experience a mild headache while taking Valtrex, you can try nonmedicinal measures such as increasing your fluid intake and resting in a cool, dark, quiet room. You can ask your doctor or pharmacist about an appropriate over-the-counter (non-prescription) medication, if needed. If your headache is persistent or very painful, consult your doctor.

Nausea

Nausea is a common side effect of Valtrex. Often, gastrointestinal side effects like nausea tend to resolve within a day or two. If the nausea is severe and/or causes vomiting, consult your doctor. If the nausea is mild, you can try to stick to foods and drinks that help settle your stomach, such as crackers and ginger ale. Avoid spicy, heavy, fatty, and fried foods. You can ask your pharmacist for Emetrol or cola syrup.

It’s unknown whether Valtrex causes other adverse effects like hair loss, weight gain, dry mouth, or any other symptoms not listed by the United States Food and Drug Administration (FDA). This is not a complete list of side effects. Other side effects may occur. Consult your healthcare provider if you have questions about the side effects of Valtrex.

A frequently asked question about Valtrex is whether it will make you urinate more often. It won’t necessarily make you pee more, but you should drink plenty of water while taking Valtrex to help the kidneys process it as best they can. Therefore, this extra hydration can result in frequent urination.

Serious side effects of Valtrex

Although it’s rare, Valtrex can cause more serious side effects that may require medical help, including:

• Kidney failure
• Nervous system problems: agitation, hallucinations, confusion, aggressive behavior, seizures, and speech problems
• Confusion
• Speech problems
• Unusual bruising or bleeding
• Depression
• Low blood cell counts
• Painful periods for women

Kidney failure

Before taking Valtrex, tell your doctor if you have any kidney problems or have ever had a kidney transplant. While taking Valtrex, drink plenty of water to help keep your kidneys work properly. Be alert to signs of kidney problems, such as urinating less frequently, tiredness, shortness of breath, and swelling in the feet or ankles.

Nervous system problems

Valtrex can cause nervous system problems. Reactions can include agitation, hallucinations, seizures, confusion, speech problems, and aggressive behavior. Nervous system problems are more likely to occur in older adults and/or people with kidney problems. Contact your healthcare provider or seek emergency medical care if these symptoms occur. Valtrex should be discontinued if nervous system problems occur.

If you’re taking Valtrex and have any of these symptoms, you should contact your doctor for medical advice as soon as possible. 

If you have any signs of an allergic reaction like difficulty breathing, hives, or swelling of the face, mouth, or throat, you should seek immediate emergency medical treatment.  

Other serious side effects that could potentially occur when taking Valtrex include: 

• Inflammation of the liver
• Renal toxicity
• Kidney failure
• A serious blood disorder called thrombotic thrombocytopenic purpura/hemolytic uremic syndrome (TTP/HUS) 

Some patients are more susceptible to these serious side effects than others. Consult your healthcare provider to find out if you’re at risk.

These side effects are very rare. Antiviral medicines are effective at treating viral infections, but after long-term use, they can eventually weaken the immune system by affecting immune cells. This is typically only an issue for seniors and people with weakened immune systems. Even though it’s not typically taken for long periods of time, if your doctor does want you to take it long term, then that’s okay. Some studies have even shown that the long-term use of Valtrex is well-tolerated for healthy individuals.

If you start to have side effects from Valtrex and are thinking about stopping the medication, you should call your doctor before doing so. Abruptly stopping Valtrex can cause new side effects or worsen symptoms. If you stop Valtrex before you’re supposed to, your viral infection may get worse because the medication hasn’t had the opportunity to work properly.

Valtrex warnings

Even though Valtrex is very effective at treating herpes virus infections, it shouldn’t be taken by everyone. You should talk with your doctor before taking Valtrex if you have any of the following medical conditions:

Underlying health conditions

You should talk with your doctor before taking Valtrex if you have any of the following medical conditions:

• HIV: Having HIV suppresses the immune system and increases the probability of getting other medical conditions. People with HIV who take Valtrex significantly increase their risk of getting TTP/HUS, a serious blood disorder.   
• Kidney or bone marrow transplants: If you’re taking Valtrex and are about to have a bone marrow or kidney transplant, you should talk with your doctor. Your risk of getting TTP/HUS will be significantly increased if you take Valtrex during your transplant process.
• Kidney problems or kidney disease: People with kidney problems or kidney disease could experience a worsening of symptoms or kidney failure if they take Valtrex.

Because of its potential to negatively affect the kidneys, some people wonder if Valtrex is also hard on the liver, but studies have shown that it’s rarely associated with mild liver injury that resolves quickly.    

Age restrictions

If you are over the age of 65, it’s best to consult with your doctor before taking Valtrex. Elderly adults may have a higher risk of experiencing side effects and are more likely to have kidney problems because of it. This doesn’t mean that you can’t take Valtrex over the age of 65. Your doctor may simply recommend a lower dose.

Pregnancy and breastfeeding

Pregnant women should talk with a healthcare professional if they’re considering taking Valtrex to learn how it might affect their pregnancy. “Through laboratory testing, Valtrex had no effects on the fetus; nevertheless, Valtrex was not adequately tested with pregnant people,” says Vikram Tarugu, MD, a gastroenterologist and the CEO of Detox of South Florida. “The safety of Valtrex has not been proven in breastfeeding babies. ” Women who are breastfeeding should consult their doctor about other approaches to feeding due to lack of information on the effect of Valtrex on breast milk.

Valtrex interactions

Taking Valtrex at the same time as certain other medications may cause additional side effects or complications. You should talk with your doctor before taking Valtrex if you’re on any of these medications:  

• Foscarnet 
• Acyclovir 
• Famciclovir
• Nephrotoxic agents 
• Bacitracin 
• Methotrexate 
• Cancer medications
• Arthritis medications 
• Medications used to prevent organ transplant rejections 
• Also, talk to your doctor if you’ve recently had a varicella virus vaccine (live) or zoster virus vaccine (live, Zostavax—not Shingrix)

Bring a complete list of all the prescription drugs and supplements you’re taking to your healthcare provider, so he or she can decide if Valtrex is right for you.     

There are currently no known interactions between Valtrex and grapefruit or grapefruit juice, which can sometimes interfere with how much of a drug stays in the body at one time.  

Alcohol, on the other hand, is best avoided while taking Valtrex. This is because when alcohol and Valtrex are combined, they can cause excessive drowsiness and dizziness.  

When it comes to caffeine and Tylenol, two of the things most likely to be consumed while on Valtrex, it’s okay to take them unless told otherwise by a medical professional.

How to avoid Valtrex side effects

1. Take the right dose at the right time of day

This is the best way to avoid Valtrex side effects. Here are the standard doses of Valtrex for adults and children:    

These dosages are only general guidelines. If your doctor prescribes Valtrex differently, then you should follow their instructions. Valtrex is most effective when started as soon as symptoms begin, so see your doctor immediately if you have symptoms. It’s safe to take Valtrex every day as long as you’ve been instructed to do so.

If you miss a dose of Valtrex, you should take the next dose as soon as possible. Taking your missed dose as soon as you remember you’ve missed it will help keep your herpes infection from worsening. Taking two doses at one time can cause serious side effects, so if you’ve missed a dose, only take one dose when you remember. However, if it’s almost time for your next dose, skip the missed dose and resume your normal schedule. 

It’s also important to remember that Valtrex has an expiration date just like any other medication. Look for the expiration date on the prescription label to see how long your particular version of Valtrex is good for. Expired medications can be less effective and risky to take. Some medications are also sensitive to heat, so be sure to store Valtrex at room temperature.

2. Take Valtrex with a full glass of water.

This helps your kidneys process it more efficiently. Once it’s been taken, Valtrex starts working to treat symptoms right away. Even though it starts working right away, it may take several days for you to notice a difference in your symptoms.

3. Switch medications if necessary.

Acyclovir (brand name Zovirax) is another antiviral drug that can be used to treat herpes virus and varicella-zoster virus infections. Neither medication is better than the other, but if someone can’t tolerate Valtrex or has an underlying medical condition that prevents them from taking it, acyclovir is another good option.  You can compare the medications here.

For herpes, side effects, composition

THERE ARE CONTRAINDICATIONS. POSSIBLE SIDE EFFECTS. A SPECIALIST’S CONSULTATION IS NECESSARY. In case of a cold

Author of the article

Khokhrina Kristina Sergeevna, pharmacist

All authors

Contents of the article

• Valtrex: composition
• Valtrex: active ingredient
• Valtrex: side effects
• Valtrex and alcohol: compatibility
• Valtrex or Aciclovir: which is better
• Valtrex or Valaciclovir
• Valtrex or Valvir: which is more effective
• Summary
• Ask an expert on the topic of the article

Many people have experienced a “cold” on the lips. The reason is the herpes simplex virus, which most often affects the skin around the lips, eyelids and genitals. According to statistics, about 3.7 billion people under the age of 50 in the world are infected with the herpes virus. This is almost 67% of the population. In most cases, the infection is asymptomatic. However, it can manifest itself at any unfavorable moment. For example, with a decrease in immunity.

The pharmacist will tell you about the Valtrex preparation: will acquaint you with its composition, active substance and side effects, and also compare it with analogues.

Valtrex: Composition

Valtrex is an antiviral drug based on Valaciclovir. Produced in Spain in the form of tablets of 500 mg. The drug blocks the reproduction of the virus by embedding in its DNA with a further chain break. In addition, the drug reduces the severity and duration of pain in certain diseases. For example, with herpes zoster.

Valtrex is available exclusively in tablet form. Valtrex ointment is not registered in Russia. Tablet excipients: microcrystalline cellulose, crospovidone, magnesium stearate and silicon dioxide, white opadry and carnauba wax.

All products Valtrex

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Valtrex: active ingredient

Valtrex tablets contain valaciclovir as an active ingredient. The drug is active against herpes viruses, cytomegalovirus, Epstein-Barr virus and others. Thus, indications for the use of Valtrex:

• Treatment of infections of the skin and mucous membranes caused by the herpes simplex virus, including genital and labial (affecting the skin around the lips and face) form
• Herpes zoster treatment
• Prevention of recurrence of herpes infections, including in immunocompromised people
• Prevention of cytomegalovirus infection and diseases after organ transplantation

Calculation of the dosage and duration of taking the drug is carried out by the attending physician, based on the indications and the severity of the process. So, for the treatment of herpes simplex virus in adults and children from 12 to 18 years old, Valtrex 500 mg is used 2 times a day.

Valtrex side effects

Valtrex herpes tablets may cause the following side effects:

• Headache and dizziness
• Nausea and vomiting
• Abdominal discomfort and diarrhea
• Confusion
• Shortness of breath
• Skin eruptions including photosensitivity and itching
• Reversible liver dysfunction
• Renal disorders
• Renal failure in patients with severe immune disorders

Valtrex and alcohol: compatibility

Valtrex and alcohol are incompatible. The simultaneous use of the drug and alcoholic beverages increases the risk of side effects. In particular, the detrimental effect on the liver, central nervous system and gastrointestinal tract. Drinking alcohol can provoke the development of hepatitis, gastritis and stomach ulcers, as well as increase the headache.

Valtrex or Aciclovir: which is better

Aciclovir is available from many pharmaceutical companies in the form of tablets, ointment and cream for external use, and powder for solution for intravenous injection.

Valaciclovir is a derivative of acyclovir with the addition of an amino acid called valine. Due to this composition, Valtrex is absorbed faster and can be used to treat cytomegalovirus infection in adults. In addition, Valtrex and Acyclovir have the following differences:

• Acyclovir tablets can be used to treat children from 3 years old, while Valtrex is indicated only from 12 years old. Accordingly, Acyclovir is used to treat chickenpox in children.
• Valtex tablets are more convenient to use. For example, in the treatment of herpes simplex virus, Valtrex is taken 2 times a day, and Acyclovir 5 times a day or every 4 hours.
• Aciclovir is available as an ointment and cream, which allows the drug to be used to treat the skin of the face and lips.
• The cost of Valtrex is several times higher.

Thus, for the treatment of cytomegalovirus infection, the drug of choice is Valtrex, and chickenpox in children is Acyclovir. The final decision on the appointment of the drug remains with the doctor.

All products Aciclovir

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Valtrex or Valaciclovir

Valaciclovir is produced in Russia and India on the basis of the substance of the same name. The drugs are almost identical: they have the same indications for use, contraindications and side effects. Their differences are in the producing countries and price category: Valaciclovir is two times cheaper. Therefore, the choice between Valtrex or Valaciclovir is recommended to be made based on personal preferences and price range.

All products Valaciclovir

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Valtrex or Valvir: which is more effective

Valvir is a drug whose active ingredient is Valaciclovir. The medicine is produced in Bulgaria in the form of tablets. Valtrex and Valvir are similar in all therapeutic parameters. However, Valvir is available in an additional dosage of 1000 mg. This is convenient for use in patients with a need for an increased dosage, since the frequency of taking pills and their number per dose is reduced.

All products Valvir

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Summary

• Valtrex is an antiviral drug based on Valaciclovir.
• The drug is active against herpes viruses, cytomegalovirus, Epstein-Barr virus and others.
• Calculation of the dosage and duration of taking the drug is carried out by the attending physician, based on the indications and the severity of the process.
• Valtrex and alcohol are incompatible.
• For the treatment of cytomegalovirus infection, the drug of choice is Valtrex, and chickenpox in children is Acyclovir.
• The choice between Valtrex or Valaciclovir is recommended based on personal preference and price range.
• Valvir is available in an additional dosage of 1000 mg, which is convenient for use in patients with a need for a higher dosage

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Doctors told what medicines should not be taken with coronavirus

The use of seemingly harmless drugs can be fatal in the case of coronavirus, doctors say. So, some antipyretic drugs can accelerate the onset of pneumonia and lead to liver failure, and antidiarrheal drugs can delay the infection in the body. Other Medications to Avoid with COVID-19, says Gazeta.Ru.

Banned aspirin

When people get sick with coronavirus, people often self-medicate and take drugs that are usually used for simple SARS and are considered safe. However, doctors warn that in the case of COVID-19, such drugs can only do harm.

This primarily applies to antipyretics and non-steroidal anti-inflammatory drugs (NSAIDs). According to Irina Vereyutina, head of the psycho-neurological department of polyclinic No. 4 of the Presidential Administration of the Russian Federation, we are talking about aspirin and analgin.

“Patients with coronavirus infection need to use paracetamol,” she noted, emphasizing that the use of aspirin and analgin in this case is “unacceptable.”

So, aspirin, due to the content of acetylsalicylic acid (a substance that has an antipyretic effect) in it against the background of infectious diseases, can cause Reye’s syndrome – a dangerous condition in which acute liver failure and hyperammonemia occur (an increase in the concentration of ammonia in the body that can cause coma and even death).

In addition, aspirin creates conditions for the penetration of the coronavirus into the lungs, which accelerates the appearance of pneumonia and alveolar lung damage, virologist Nadezhda Zholobak told the Vechernyaya Moskva newspaper in an interview.

Mayo Clinic USA found that non-steroidal anti-inflammatory drugs can lead to heart attack or stroke.

US scientists analyzed data from 56,000 adults with high blood pressure who had taken NSAIDs for a long time. As a result of the observation, it turned out that one in 330 people who used such drugs had a heart attack or stroke within four weeks. They also noticed that the drug celecoxib caused the highest risk of adverse reactions, with a heart attack occurring in 1 in 105 patients.

Given that the coronavirus quite often damages the cardiovascular system, taking NSAIDs can lead to even greater complications.

“Due to covid, blood clotting is disrupted, which leads to the formation of microthrombi, and changes in the stiffness of the vascular wall cause high blood pressure – and these are just some of the consequences of the virus,” a cardiologist, head of the rehabilitation treatment department at the Tyumen Cardiology Research Center, Timofey Semenikhin told Argumenty i Fakty newspaper.

In turn, cardiologist Yuri Kuzmenkov previously reported that long-term use of NSAIDs can also cause the development of gastropathy – damage to the mucous membrane of the stomach and duodenum, leading to the development of erosions and ulcers. In addition, according to him, various dyspeptic disorders often occur with gastropathy (digestive disorders – Gazeta.Ru).

Diarrhea and runny nose are better tolerated

Meanwhile, American physician and infectious disease specialist Joshua Schaffzin says it is dangerous to use antidiarrheal drugs to treat symptoms of COVID-19. He spoke about this to Good Housekeeping magazine.

“Slowing down of the intestines can result in incomplete removal of the infection and elimination of inflammation,” the physician explained. According to him, nausea and diarrhea are indicators that the digestive tract is in the process of destroying bacteria, and this should not be interfered with.

Therefore, all medicines containing the antidiarrheal drug loperamide are contraindicated. “The main thing is to drink water and just let the process take its course,” the expert said.

Some decongestants and inhalers, which should only be used by asthma patients, will also harm a coronavirus patient, Schaffzin said.

The specialist pointed out that all products that contain phenylephrine, the active ingredient in many popular over-the-counter nasal decongestants, can be especially harmful for people with cardiovascular problems.

“These drugs cause small blood vessels in the nose to close. For people with high blood pressure, this can really be a problem because it will cause blood vessels to close in other places as well.”0005

— the expert added.

Antibiotics will not save

The use of antibiotics can also cause considerable harm to the body during a coronavirus infection, said Roman Kozlov, chief microbiologist and specialist in antimicrobial resistance of the Ministry of Health of Russia, Corresponding Member of the Russian Academy of Sciences.