How does Dulcolax work to relieve constipation. What are the common side effects of Bisacodyl. When should you avoid taking Dulcolax. How long does it take for Dulcolax to cause a bowel movement. What precautions should be taken when using Bisacodyl.

Understanding Dulcolax: A Powerful Constipation Relief Medication

Dulcolax, also known by its generic name Bisacodyl, is a widely used medication for treating constipation. This stimulant laxative works by increasing intestinal movement, facilitating the passage of stool. While it’s an effective solution for many, it’s crucial to understand its proper use, potential side effects, and precautions.

What is Dulcolax used for?

Dulcolax serves two primary purposes:

• Treatment of constipation
• Bowel preparation before medical examinations or surgeries

Its mechanism of action involves stimulating the intestines to increase peristalsis, the wave-like muscle contractions that move food through the digestive tract.

Proper Administration of Dulcolax: Dosage and Timing

Correct administration of Dulcolax is crucial for its effectiveness and to minimize potential side effects. Here are some key points to remember:

• Take the medication orally as directed by your healthcare provider
• If self-treating, carefully follow the instructions on the product package
• Swallow the tablet whole without crushing, chewing, or breaking it
• Avoid taking Dulcolax within an hour of consuming antacids, milk, or milk products

Is there a specific time frame for Dulcolax to take effect. Typically, it takes 6 to 12 hours for Dulcolax to cause a bowel movement. However, individual responses may vary.

Dosage Considerations

The appropriate dosage of Dulcolax depends on several factors:

• Age of the patient
• Medical condition being treated
• Individual response to the medication

It’s important not to exceed the recommended dose or use the medication for more than 7 days without medical supervision. Overuse can lead to serious side effects and potential health complications.

Potential Side Effects of Dulcolax: What to Watch For

While Dulcolax is generally well-tolerated, it can cause various side effects. Some common ones include:

• Stomach or abdominal pain and cramping
• Nausea
• Diarrhea
• Weakness

These effects are usually mild and transient. However, if they persist or worsen, it’s advisable to consult a healthcare professional.

Serious Side Effects Requiring Immediate Attention

In rare cases, Dulcolax may cause more severe side effects that require prompt medical attention:

• Persistent nausea, vomiting, or diarrhea
• Muscle cramps or weakness
• Irregular heartbeat
• Dizziness or fainting
• Decreased urination
• Mental or mood changes, such as confusion

Do these side effects indicate a serious problem. While not common, these symptoms could signify a more severe reaction to the medication and should be evaluated by a healthcare provider immediately.

Precautions and Interactions: Ensuring Safe Use of Dulcolax

Before starting Dulcolax, it’s crucial to inform your healthcare provider about any allergies, medical conditions, or medications you’re currently taking. This information helps prevent potential complications and adverse interactions.

Medical Conditions to Disclose

Be sure to inform your doctor if you have a history of:

• Appendicitis or symptoms suggesting appendicitis
• Sudden changes in bowel habits lasting more than two weeks
• Rectal bleeding
• Intestinal blockage

Pregnancy and Breastfeeding Considerations

If you’re pregnant or breastfeeding, consult your healthcare provider before using Dulcolax. Long-term use during pregnancy is not recommended, and it’s unclear whether the medication passes into breast milk.

Potential Drug Interactions

Dulcolax may interact with certain medications, potentially altering their effectiveness or increasing the risk of side effects. Notable interactions include:

• Medications that decrease stomach acid (e.g., H2 blockers like ranitidine, proton pump inhibitors like omeprazole)
• Antacids
• Milk and milk products

To avoid potential interactions, maintain an up-to-date list of all medications, including over-the-counter drugs and herbal supplements, and share it with your healthcare providers.

When to Seek Medical Attention: Recognizing Serious Symptoms

While Dulcolax is generally safe when used as directed, certain symptoms may indicate a need for immediate medical attention:

• Severe or persistent abdominal pain
• Rectal bleeding
• No bowel movement within 12 hours of taking the medication
• Signs of dehydration (e.g., excessive thirst, dry mouth, decreased urination)
• Symptoms of an allergic reaction (e.g., rash, itching, swelling, severe dizziness, difficulty breathing)

Can these symptoms be managed at home. While mild discomfort might be normal, these more severe symptoms require professional medical evaluation and should not be self-treated.

Long-term Use of Dulcolax: Risks and Considerations

While Dulcolax can be an effective short-term solution for constipation, long-term use carries potential risks:

• Dependence on laxatives for bowel movements
• Electrolyte imbalances
• Dehydration
• Weakening of the bowel muscles

For chronic constipation, it’s essential to consult a healthcare provider to address underlying causes and develop a comprehensive treatment plan.

Alternatives to Long-term Laxative Use

For those dealing with recurring constipation, consider these lifestyle modifications:

• Increasing dietary fiber intake
• Staying well-hydrated
• Engaging in regular physical activity
• Establishing a consistent bathroom routine
• Managing stress levels

These natural approaches can often help regulate bowel movements without the need for long-term medication use.

Overdose Risks: Recognizing and Responding to Excessive Dulcolax Use

Taking more than the recommended dose of Dulcolax can lead to serious health complications. Symptoms of overdose may include:

• Severe abdominal pain
• Persistent vomiting or diarrhea
• Dehydration
• Electrolyte imbalances
• Muscle weakness or spasms

How should one respond to a suspected overdose. If you suspect an overdose, especially if accompanied by serious symptoms like loss of consciousness or difficulty breathing, call emergency services immediately. For less severe cases, contact a poison control center for guidance.

Preventing Accidental Overdose

To minimize the risk of overdose:

• Always follow the recommended dosage instructions
• Keep medications out of reach of children
• Never share your prescription with others
• Dispose of unused medication properly

By adhering to these precautions, you can help ensure safe and effective use of Dulcolax.

Natural Alternatives to Dulcolax: Exploring Gentler Options

While Dulcolax can be effective for acute constipation, some individuals prefer to explore natural alternatives. Here are some options that may help alleviate constipation without the use of stimulant laxatives:

Dietary Modifications

• Increase fiber intake through fruits, vegetables, and whole grains
• Stay well-hydrated by drinking plenty of water throughout the day
• Incorporate probiotic-rich foods like yogurt and kefir into your diet

Lifestyle Changes

• Engage in regular physical activity to stimulate bowel movements
• Practice stress-reduction techniques like meditation or yoga
• Establish a consistent bathroom routine

Natural Supplements

• Psyllium husk, a natural fiber supplement
• Magnesium citrate, which can help draw water into the intestines
• Aloe vera juice, known for its potential laxative effects

Are these natural alternatives as effective as Dulcolax. While these options may work well for some individuals, their effectiveness can vary. It’s important to consult with a healthcare provider before starting any new treatment regimen, especially if you have chronic constipation or other digestive issues.

By understanding the proper use, potential side effects, and alternatives to Dulcolax, individuals can make informed decisions about managing their constipation. Remember, while over-the-counter medications like Dulcolax can provide relief, persistent digestive issues should always be evaluated by a healthcare professional to ensure appropriate treatment and rule out any underlying conditions.

Dulcolax (Bisacodyl) Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Uses

Bisacodyl is used to treat constipation. It may also be used to clean out the intestines before a bowel examination/surgery. Bisacodyl is known as a stimulant laxative. It works by increasing the movement of the intestines, helping the stool to come out.

How to use Dulcolax

Take this medication by mouth as directed by your doctor. If you are self-treating, follow all directions on the product package. If you have any questions, ask your doctor or pharmacist.

Swallow this medication whole. Do not crush, chew, or break the tablet or take it within 1 hour of antacids, milk, or milk products. Doing so can destroy the coating on the tablet and may increase the risk of stomach upset and nausea.

Dosage is based on your age, medical condition, and response to treatment. Do not increase your dose or take this drug more often than directed. Do not take this medication for more than 7 days unless directed by your doctor. Serious side effects may occur with overuse of this medication (see also Side Effects section).

It may take 6 to 12 hours before this medication causes a bowel movement. Tell your doctor if your condition lasts or gets worse, or if bleeding from the rectum occurs. If you think you may have a serious medical problem, get medical help right away.

Side Effects

Stomach/abdominal pain or cramping, nausea, diarrhea, or weakness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: nausea/vomiting/diarrhea that doesn’t stop, muscle cramps/weakness, irregular heartbeat, dizziness, fainting, decreased urination, mental/mood changes (such as confusion).

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking bisacodyl, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: appendicitis or symptoms of appendicitis (such as nausea/vomiting, sudden or unexplained stomach/abdominal pain), a sudden change in bowel habits that lasts for longer than 2 weeks, bleeding from the rectum, intestinal blockage.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Tell your doctor if you are pregnant before using this medication. Using it for long periods during pregnancy is not recommended. Consult your doctor for more details.

It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Interactions

See also How To Use section.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

Some products that may interact with this drug are: medications that decrease stomach acid (such as h3 blockers like ranitidine, proton pump inhibitors like omeprazole).

Does Dulcolax interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: nausea/vomiting/diarrhea that doesn’t stop, severe stomach/abdominal pain or cramping.

Keep all medical and lab appointments.

Lifestyle changes that may prevent or relieve constipation include exercising, drinking enough water, and eating a proper diet with fiber-rich foods such as bran, fresh fruits/vegetables. Talk to your doctor or pharmacist about lifestyle changes that might benefit you.

If your doctor has directed you to take this medication on a regular schedule and you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Different brands of this medication have different storage needs. Check the product package for instructions on how to store your brand, or ask your pharmacist. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Images

Dulcolax (bisacodyl) 5 mg tablet,delayed release

Color: orangeShape: roundImprint: BI 12

This medicine is a orange, round, coated, tablet imprinted with “BI” and “12”.

Dulcolax (bisacodyl) 5 mg tablet,delayed release

Color: orangeShape: roundImprint: BI 12

This medicine is a orange, round, coated, tablet imprinted with “BI” and “12”.

Dulcolax (bisacodyl) 5 mg tablet,delayed release

Color: orangeShape: roundImprint: BI 12

This medicine is a orange, round, coated, tablet imprinted with “BI” and “12”.

Next

Save up to 80% on your prescriptions.

Available coupons

Save up to 80% on your prescription with WebMDRx

Drug Survey

Have you ever purchased Dulcolax?

Yes, In the past 3 months

Yes, In the past 6 months

Yes, In the past year

Haven’t purchased but considering

Don’t plan to purchase

This survey is being conducted by the WebMD marketing sciences department.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

Dulcolax – Uses, Side Effects, Interactions

How does this medication work? What will it do for me?

Bisacodyl belongs to the class of medications called stimulant laxatives. It is used for the relief of occasional constipation. It can also be used for the preparation of certain medical tests (e.g., colonoscopy), before and after surgery, and in other situations where a bowel movement to required.
It works by stimulating the bowel muscles and also accumulates water in the intestines. This helps to soften the stool and produce a bowel movement more quickly. The tablets should be taken at bedtime to produce a bowel movement the next morning. The suppositories usually take about 15 minutes to 1 hour to work.

This medication may be available under multiple brand names and/or in several different forms.  Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor or pharmacist has not recommended it.

What form(s) does this medication come in?

Suppositories
Each rectal suppository contains bisacodyl 10 mg (adult formula). Nonmedicinal ingredient: hard fat.

Tablets
Each yellow, enteric-coated tablet contains bisacodyl 5 mg. Nonmedicinal ingredients: acacia, white wax, carnauba wax, corn starch (dried/soluble), methacrylic acid and ethyl acrylate copolymer dispersion, glycerine, lactose monohydrate, magnesium stearate, polyethylene glycol, sucrose, talc, glyceryl monostearate, triethyl citrate, polysorbate 80, D&C Yellow #10 Aluminum Lake, D&C red no. 30, povidone, sodium benzoate, methylparaben, propylparaben and titanium dioxide.

Dulcolax for Women
Each enteric-coated tablet contains bisacodyl 5 mg. Nonmedicinal ingredients: acacia, ammonium hydroxide, carnauba wax, corn starch, D&C Red #27 aluminum lake, FD&C Blue #2 aluminum lake, FD&C Yellow #6 aluminum lake, iron oxide black, glycerin, glyceryl monostearate, lactose monohydrate, magnesium stearate, methacrylic acid and ethyl acrylate copolymer, methylparaben, modified starch, polyethylene glycol, polysorbate 80, povidone, propylene glycol, propylparaben, shellac, sodium benzoate, sucrose, talc, titanium dioxide, triethyl citrate, and white wax.

How should I use this medication?

For constipation, the usual dose for adults and children over 12 years of age is 1 to 2 tablets (5 mg to 10 mg) taken by mouth, or 1 adult suppository (10 mg) inserted rectally. For children 6 to 12 years of age, the usual dose is 1 tablet (5 mg) taken by mouth.

Before a medical test or surgery, the usual dose for adults is 2 to 4 tablets (10 mg to 20 mg) by mouth the night before the procedure, followed by 1 suppository inserted rectally the morning of the procedure.

Take the tablets at night to produce a bowel movement the following morning. Do not take the tablets with milk or antacids as this may dissolve the coating on the tablet. Swallow the tablets whole with liquids. Do not crush or chew the tablets.

To use the suppositories, unwrap and insert high into the rectum with the pointed end first. Then, push the flat end of the suppository sideways so that part of it touches the wall of the rectum. Keep the suppository in the rectum for as long as possible. If inserting the suppository is difficult because you have had anal fissures or hemorrhoids, coat the end of the suppository with a lubricant such as petroleum jelly before inserting. The suppositories will start to work within 15 minutes to 1 hour.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.

Do not take this medication for longer than one week, unless directed by a health care professional. If you use this medication for one week and you do not produce a bowel movement, contact your doctor immediately.

It is important to take this medication exactly as prescribed by your doctor or recommended by your pharmacist. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not administer a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Who should NOT take this medication?

Do not take this medication if you:

• are allergic to bisacodyl or any ingredients of the medication
• are severely dehydrated
• have a rare inherited condition where you cannot take lactose or sucrose (e.g., galactosemia, fructose intolerance)
• have intestinal blockage, appendicitis, acute inflammatory bowel disease (e. g., Crohn’s disease, ulcerative colitis), or severe abdominal pain with nausea and vomiting

What side effects are possible with this medication?

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

• abdominal cramps, pain, or discomfort
• diarrhea
• nausea
• vomiting

Although most of the side effects listed below don’t happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• blood in the stool
• dizziness
• fainting
• rectal discomfort or pain
• symptoms of an allergic reaction (e.g., rash, itching)
• symptoms of dehydration (e.g., dry, sticky mouth; thirst; decreased urine production)
• symptoms of irritation of the intestines (e.g., severe abdominal cramping, diarrhea)

Stop taking the medication and seek immediate medical attention if any of the following occur:

• symptoms of a severe allergic reaction (e.g., hives, swelling of the face or throat)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.

Are there any other precautions or warnings for this medication?

Before you begin taking a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should take this medication.

Abdominal pain, nausea, vomiting, fever: If you have abdominal pain, nausea, fever, or vomiting, do not take this medication. Talk to your doctor or pharmacist for advice.

Dizziness and fainting: People taking this medication have reported experiencing dizziness and fainting. This may be from straining to produce a bowel movement or from the pain that can be associated with constipation. If you feel dizzy or faint while taking this medication, contact your doctor.

Long-term use: This medication should not be taken daily or for long periods of time as this may lead to dehydration and low potassium levels. Long-term use can make your bowels dependent on this medication to function.

Rectal conditions: If you have rectal fissures or ulcerative proctitis, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. People with these conditions may experience pain and irritation when using the suppository form of this medication. If you experience rectal bleeding after using the suppositories, contact your doctor.

Tartrazine: This medication contains tartrazine (a colouring agent) and should not be taken by people who are allergic to tartrazine.

Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.

Breast-feeding: This medication does not pass into breast milk. It is therefore considered safe to use while breast-feeding.

Children: The safety and effectiveness of this medication have not been established for children less than 6 years old. Do not give this medication to children unless recommended by your doctor.

What other drugs could interact with this medication?

Do not take other medications 2 hours before or 2 hours after taking bisacodyl tablets. Bisacodyl tablets may reduce the effectiveness of other medications.

There may be an interaction between bisacodyl and any of the following:

• antacids (e.g., aluminum hydroxide, calcium carbonate, magnesium hydroxide)
• corticosteroids (e.g., dexamethasone, hydrocortisone, prednisone)
• digoxin
• diuretics (e.g., furosemide, hydrochlorothiazide)
• h3-antagonists (e.g., ranitidine, cimetidine)
• polyethylene glycol (PEG) solution
• proton pump inhibitors (PPIs; e.g., omeprazole, pantoprazole)

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them.  Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

All material copyright MediResource Inc. 1996 – 2023. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/drug/getdrug/Dulcolax

Catalog :: Medicines :: Digestive system :: Laxatives :: Dulcolax® 5mg №30 tab.

Dosage form, dosage

Enteric coated tablets 5 mg

Pharmacotherapeutic group

Digestive tract and metabolism. Drugs for the treatment of constipation. Contact laxatives. Bisacodyl.

ATX code A06AB02

Indications for use

• symptomatic treatment of constipation

Checklist before use

Contraindications

• hypersensitivity to bisacodyl or other components of the drug
• severe dehydration
• acute inflammatory bowel disease, ulcerative colitis, Crohn’s disease
• severe abdominal pain of indeterminate location, including severe pain accompanied by nausea and vomiting, which may indicate a serious illness
• occlusive and subocclusive syndromes
• persons with hereditary fructose intolerance, Lapp-lactase enzyme deficiency, glucose-galactose malabsorption
• children under 6 years of age

9000 3 Necessary precautions for use

Drug therapy for constipation should be be accompanied by the following hygiene and dietary measures:

• diet rich in fiber and fluids
• adherence to recommendations for physical activity and rules for the normalization of bowel movements.

Long-term use (more than 10 days) is not recommended as it may cause:

• severe functional bowel disorder, melanosis, fluid and electrolyte imbalance and hypokalemia.
• drug dependence with regular need for laxatives, the need to increase the dosage and severe constipation upon withdrawal. Addiction varies among patients and can occur without the knowledge of the physician.

In patients suffering from fluid loss, where dehydration can be dangerous (renal failure, elderly patients), the use of the drug should be suspended and resumed only under medical supervision. Loss of fluids can cause dehydration, signs of which may include thirst and oliguria.

The simultaneous use of the drug with drugs that cause bidirectional ventricular tachycardia is not recommended

Patients may experience rectorrhagia (look for blood in the stool), which is usually mild and self-limiting. If you have rectorrhagia, you should contact your doctor.

Cases of dizziness and fainting have been reported, presumably related to defecation.

In children, stimulant laxatives should only be used in exceptional cases, as the risk of impaired defecation reflex function must be taken into account.

Simultaneous use with other laxatives may increase the gastrointestinal side effects of Dulcolax®.

The drug is not recommended for persons with hereditary fructose or galactose intolerance, Lapp-lactase or sucrase-isomaltase deficiency, glucose and/or galactose malabsorption.

The drug Dulcolax® contains castor oil, which can cause gastrointestinal disturbances (mild laxative effect, diarrhoea).

Interactions with other drugs

Undesirable combinations 05

• antiarrhythmics : amiodarone, bretylium, disopyramide, quinidine, sotalol
• not antiarrhythmics preparations : astemizole, bepridil, erythromycin IV, halofantrine, pentamidine, sultropide, terfenadine, vincamine

Non-stimulant laxatives should be used.

Combinations requiring precautions for use

Medicines containing digitalis:

Hypokalemia increases the toxic effect of medicines containing digitalis. The level of potassium in the blood should be monitored and, if necessary, an ECG should be performed. Non-stimulant laxatives should be used.

Other potassium-lowering drugs:

Hypokalemic diuretics (singly or in combination), amphotericin B (intravenously), corticosteroids (glucocorticoids and mineralocorticoids: systemic route of administration), tetracosactide. Increased risk of hypokalemia (additive effect). Monitoring and, if necessary, correction of the level of potassium in the blood is required. Non-stimulant laxatives should be used.

Co-administration of with upper GI deacidifiers, such as alkaline preparations, antacids, proton pump inhibitors, or milk, may reduce tablet shell resistance and lead to dyspepsia and stomach irritation.

Special warnings

Pregnancy

The drug is not recommended during pregnancy, as the available clinical and preclinical data are insufficient.

Lactation

According to data, neither bisacodyl nor its glucuronides pass into the breast milk of lactating women, so Dulcolax ^® can be used during lactation.

Fertility

Human fertility studies have not been conducted.

Features of the effect of the drug on the ability to drive vehicles or potentially dangerous mechanisms

Studies have not been conducted. However, patients should be aware of the possibility of dizziness and/or fainting due to the parasympathetic vascular response to constipation-related abdominal pain.

Directions for use

Dosage regimen

Adults: maximum dose 1-2 tablets (5-10 mg) per day.

Children

Children aged 6 to 12 years 1 tablet (5 mg) 1 time per day for 2 to 10 days.

In children under 12 years of age with chronic or prolonged constipation, the use of the drug is possible only on prescription!

Method and route of administration

Treatment is recommended to start with the lowest dose. Dosage may be adjusted to the maximum recommended daily dose until regular stools are obtained. Exceeding the maximum daily dosage is unacceptable.

Tablets are recommended to be taken at night (effect after 10 hours) for stools the next morning, or in the morning on an empty stomach (effect after 5 hours). The tablets should be swallowed whole with a sufficient amount of liquid.

It is not recommended to take tablets along with products that lower the acidity of the upper gastrointestinal tract, such as milk, antacids or proton pump inhibitors, in order to prevent premature dissolution of the shell of the tablet

Measures, which must be taken in case of an overdose of 9000

Symptoms: diarrhea, dehydration, abdominal cramps, impaired potassium and other electrolyte metabolism.

Chronic overdose of Dulcolax ^® may cause diarrhea, abdominal pain, hypokalemia, which may be associated with muscle weakness.

Cases of renal tubular lesions, metabolic alkalosis, secondary aldosteronism, and urolithiasis have also been described in association with chronic abuse of laxatives.

Treatment: symptomatic. It may be necessary to restore water and electrolyte imbalance, which is especially important for elderly patients and children. It may be useful to take antispasmodics.

Description of adverse reactions that occur with the standard use of drugs and measures to be taken in this case (if necessary)

Adverse events are listed below by system organ class and frequency according to the following classification: very often (≥ 1/10), common (≥ 1/100 to <1/10), uncommon (≥1/1000 to <1/100), rare (≥1/10,000 to <1/1000 ), very rare (<1/10,000), frequency unknown (adverse reactions, the frequency of which is unknown, since it cannot be estimated from the available data).

Common ( ≥ 1/100 to <1/10)

• diarrhea, nausea, abdominal pain and cramps

Uncommon ( ≥1/1000 to <1/100)

• rectorrhagia (blood in the stool), anorectal discomfort (burning and anorectal pain), vomiting
• dizziness*

Rare ( ≥1/10,000 to <1/1000)

• anaphylactic reactions, angioedema
• generalized pruritus

900 21 dehydration

• syncope*
• colitis, including ischemic colitis

*available information suggests that dizziness and syncope are presumably associated with a parasympathetic vascular reaction in abdominal cramps and defecation

Frequency unknown (adverse reactions, the frequency of which is unknown, as it cannot be estimated from the available data)

• hypokalemia

Composition of the medicinal product mg,

excipients: lactose monohydrate, dried corn starch, soluble starch, glycerin 85 %, magnesium stearate,

shell composition: magnesium stearate, sucrose, talc, acacia (powder), titanium dioxide (E 171), copolymer of methacrylic acid and methyl methacrylate (1 : 1) (Eudragit L 100), copolymer of methacrylic acid and methyl methacrylate (1: 2) (Eudragit S 100), castor oil, macrogol 6000, yellow iron oxide (E 172), white wax, carnauba wax, shellac, purified water, anhydrous ethanol, acetone.

Description of appearance, odor, taste

Round, biconvex tablets, sugar/enteric-coated beige-yellow color with a smooth shiny surface. Tablet diameter is from 5.8 mm to 6.2 mm, thickness is from 3.2 mm to 3.8 mm.

Release form and packaging

10 tablets are placed in blisters made of PVC film and aluminum foil.

3 blister packs, together with instructions for medical use in Kazakh and Russian, are put into a cardboard pack.

Shelf life

3 years.

Do not use after the expiration date.

Storage conditions

Store below 25°C.

Keep out of reach of children!

Pharmacy conditions

Without prescription

Producer information

Delpharm Reims, Reims, France

10 rueColonel Charbon neaux, 51100 Reims, France

phone: +330326888110

Active ingredient

Bisacodyl

Dosage form

oral tablets

Need

9002 1

Laxatives

Thermolabile mode

No

Dispensing conditions

OTC

Find Similar

Available Shipping Methods

• Courier “to the door”

Dulcolax pico 30 ml drops

Instructions for medical use

Dulcolax® Pico

Trade name

Dulcolax Pico

International generic name

Sodium picosulfate

Dosage form

Oral drops 7 . 5 mg/ml 15 ml, 30 ml

Composition

100 ml contains

active substance – sodium picosulfate monohydrate 7.5 mg,

excipients: sodium benzoate, liquid sorbitol (not crystallized), sodium citrate dihydrate, citric acid monohydrate, purified water.

Description

Clear, colorless to yellow or light yellow-brown, slightly viscous solution with almost imperceptible odor

Pharmacotherapeutic group

Laxatives. Contact laxatives.

Sodium picosulfate.

ATC code A06AB08

Pharmacological properties

Pharmacokinetics

Absorption. After ingestion, sodium picosulfate reaches the large intestine without being absorbed from the gastrointestinal tract and thus without being exposed to the hepatic circulation.

Biotransformation. Sodium picosulfate is converted to the active compound of the drug bis-(p-hydroxyphenyl)-pyridyl-2-methane in the distal segment of the intestine by cleavage by intestinal bacteria.

Elimination. After conversion, only a small amount of bis-(p-hydroxyphenyl)-pyridyl-2-methane is absorbed and combined in the intestinal wall and liver to form inactive bis-(p-hydroxyphenyl)-pyridyl-2-methane glucuronide. After ingestion of 10 mg sodium picosulfate, 10.4% of the total dose is excreted as bis-(p-hydroxyphenyl)-pyridyl-2-methane glucuronide in the urine after 48 hours. In general, urinary excretion decreases when higher doses of sodium picosulfate are taken.

The time of development of the laxative effect of the drug is determined by the rate of release of the active metabolite and is 6-12 hours. There is no direct or inverse relationship between the laxative effect of the active metabolite and its serum concentration.

Pharmacodynamics

Sodium picosulfate, the active ingredient in Dulcolax Pico, is a locally acting laxative from the triarylmethane group. After bacterial digestion in the colon, it stimulates its mucous membrane, reduces the absorption of electrolytes and water, and enhances intestinal motility.

The active form of the drug, formed by hydrolysis under the influence of intestinal microorganisms, directly excites the nervous structures of the intestinal wall, as a result of which the passage of intestinal contents is accelerated.

As a colonic laxative, sodium picosulfate specifically stimulates the natural bowel movement in the lower gastrointestinal tract. Thus, sodium picosulfate is ineffective in altering digestion or absorption of calories or essential nutrients in the small intestine.

Indications for use

– constipation and conditions requiring assistance in emptying the intestines (atonic constipation, stool regulation (hemorrhoids, proctitis, anal fissures), preparation for surgical operations, instrumental and x-ray studies).

Route of administration and doses

It is recommended to start taking the drug with the minimum sufficient dose. To obtain the desired effect, the dose may be increased to the maximum recommended dose. Do not exceed the maximum recommended dose.

The drug is recommended to be taken at night, before going to bed, to ensure bowel movements the next morning.

1 ml contains 7.5 mg (=15 drops)

Adults: 10-20 drops (5-10 mg) per day

Children over 10 years old: 10-20 drops (5-10 mg) per day

Children aged 4-10 years: 5-10 drops (2.5-5 mg) per day

Children under 4 years of age: the recommended dose is 0.25 mg per kg of body weight per day sodium picosulfate).

Side effects

Side effects are defined as follows:

Very common ≥ 1/10

Common ≥ 1/100 – < 1/10

Uncommon ≥ 1/1,000 – < 1/100 900 05

Rare ≥ 1 /10,000 – < 1/1,000

Very rare < 1/10,000

Unknown frequency cannot be estimated from available data

Immune system disorders:

Unknown:

– hypersensitivity

Nervous system disorders:

Uncommon:

– dizziness and defecation))

Gastrointestinal disorders:

Very common

Diarrhea

Common

Abdominal pain

Abdominal cramps

Abdominal discomfort

5

Uncommon:

– nausea, vomiting

Dermatological disorders:

Unknown:

– skin reactions such as angioedema, drug dermatitis, rash, itching

Contraindications

– ileus or intestinal obstruction

– severe febrile conditions with severe abdominal pain (eg appendicitis) associated with possible nausea and vomiting

– acute inflammatory bowel disease

– severe dehydration

– hypersensitivity to sodium picosulfate or other components of the drug

– hereditary intolerance to fructose and galactose (see “Special instructions”)

Drug interactions

Glucocorticosteroids, diuretics increase the risk of developing electrolyte disturbances with increasing doses. This may increase the sensitivity to cardiac glycosides.

Broad-spectrum antibiotics reduce the laxative effect.

Precautions

As with any laxative, DULCOLAX PIKO should not be taken daily or for long periods without determining the cause of constipation. This can lead to a violation of the water and electrolyte balance, as well as cause hypokalemia.

Cases of dizziness and/or fainting have been observed in patients taking Dulcolax Pico, which may be associated with straining during bowel movements or with a parasympathetic reaction to abdominal pain associated with constipation, and not necessarily with the use of sodium picosulfate.

Not recommended for use in children without first consulting a doctor.

1 ml drops contains 0.45 g of sorbitol, which is equal to 0.6 g of sorbitol per maximum recommended daily dosage for the treatment of adults and children over 10 years of age. Patients with hereditary fructose intolerance should not take this medicine.

Fertility, pregnancy and lactation

Adequate and well-controlled studies of the effects of the drug on the body of pregnant women have not been conducted. However, many years of experience with the use of the drug during pregnancy did not reveal any cases of unwanted or side effects.

However, Dulcolax Pico, like all other medicines, should be used during pregnancy with caution and under medical supervision. If necessary, the use of the drug should evaluate the potential benefit of therapy for the mother and the possible risk to the fetus.

According to clinical data, neither sodium picosulfate nor its glucuronides pass into the breast milk of lactating women, so Dulcolax Pico can be used during breastfeeding.

Studies of the effect of the drug on human fertility have not been conducted.

Features of the effect of the drug on the ability to drive a vehicle or potentially dangerous mechanisms

The effect of the drug on the ability to drive a vehicle or potentially dangerous mechanisms has not been studied. However, patients should be aware that adverse events such as dizziness and/or fainting may occur due to a parasympathetic vascular response (eg, abdominal cramps). In the event of abdominal cramps, patients should avoid potentially hazardous activities, including driving vehicles or using various mechanisms.

Overdose

Symptoms: diarrhea, abdominal pain, dehydration, clinically significant loss of fluid, potassium and other electrolytes.

In chronic overdose, ischemia of the colonic mucosa, chronic diarrhea, abdominal pain, hypokalemia, secondary hyperaldosteronism, and urolithiasis may develop.

Chronic laxative abuse may result in renal tubular damage, metabolic alkalosis, and muscle weakness associated with hypokalemia.

Treatment: induction of vomiting or gastric lavage, infusion therapy and correction of water and electrolyte imbalance, antispasmodics.

Presentation and packaging

15 ml or 30 ml in a plastic bottle sealed with a dropper stopper and a screw cap.