What are the primary uses of Fioricet for headache treatment. How does Fioricet interact with other medications. What are the common and rare side effects of Fioricet. How should Fioricet be dosed and what precautions should be taken.

Understanding Fioricet: A Powerful Headache Medication

Fioricet is a combination medication widely prescribed for the treatment of tension headaches and migraines. This potent drug consists of three active ingredients: butalbital (a barbiturate), acetaminophen (a pain reliever), and caffeine. Each component plays a specific role in alleviating headache symptoms, making Fioricet a go-to option for many patients suffering from severe headaches.

Why is Fioricet effective for headaches? The barbiturate component, butalbital, acts as a relaxant for the muscle contractions often associated with tension headaches. Acetaminophen reduces pain and lowers fever, while caffeine enhances the pain-relieving effects of acetaminophen and helps constrict blood vessels in the brain, potentially reducing headache intensity.

Fioricet’s Primary Uses and Benefits

Fioricet is primarily prescribed for tension headaches, which are characterized by a dull, constant pain often described as a tight band around the head. However, its applications extend beyond this primary use:

• Treatment of migraine headaches
• Management of post-dural puncture headaches
• Relief from headaches associated with sinusitis
• Alleviation of dental pain

Can Fioricet be used for other types of pain? While primarily indicated for headaches, some physicians may prescribe Fioricet off-label for other pain conditions. However, it’s crucial to use this medication only as directed by a healthcare professional due to its potential for dependence and side effects.

Understanding Fioricet’s Side Effects: What to Watch For

As with any medication, Fioricet can cause side effects ranging from mild to severe. Understanding these potential reactions is crucial for patients and healthcare providers alike.

Common Side Effects

The most frequently reported side effects of Fioricet include:

• Drowsiness
• Dizziness
• Gastrointestinal irritation
• Insomnia
• Nervousness

Are these side effects typically severe? While common, these side effects are generally considered less severe and often subside as the body adjusts to the medication. However, if they persist or worsen, it’s important to consult a healthcare provider.

Infrequent Side Effects

Less common but potentially more concerning side effects may include:

• Abnormal liver function tests
• Confusion
• Excessive excitement
• Fatigue and weakness
• Nightmares
• Constipation
• Fainting
• Vertigo

Should patients be concerned about these infrequent side effects? While less common, these side effects may indicate a more serious reaction to the medication. Patients experiencing these symptoms should seek medical attention promptly.

Rare but Serious Side Effects

In rare cases, Fioricet may cause severe adverse reactions, including:

• Thrombocytopenia (decreased blood platelets)
• Agranulocytosis (very low levels of granulocytes)
• Leukopenia (low white blood cell count)
• Neutropenia (low neutrophil count)
• Acute liver failure
• Severe skin reactions

How quickly should a patient seek medical attention for these rare side effects? Immediate medical attention is crucial if any of these rare but serious side effects occur. They can be life-threatening and require prompt intervention.

Fioricet Drug Interactions: What Patients Need to Know

Drug interactions can significantly alter the effectiveness of Fioricet or increase the risk of side effects. Understanding these potential interactions is crucial for safe and effective treatment.

Common Drug Interactions

Fioricet may interact with various medications, including:

• Acetazolamide
• Darunavir
• Dichlorphenamide
• Ketorolac
• Lithium
• Methotrexate
• Certain antibiotics (e.g., penicillin, sulfonamides)
• Gout medications (e.g., probenecid, sulfinpyrazone)

Why is it important to inform healthcare providers about all medications? Providing a complete list of all medications, including over-the-counter drugs and herbal supplements, allows healthcare providers to assess potential interactions and adjust treatment plans accordingly.

Interactions Affecting Blood Thinning

Fioricet may increase the risk of bleeding when taken with certain medications, such as:

• Antiplatelet drugs (e.g., clopidogrel)
• Anticoagulants (e.g., dabigatran, enoxaparin, warfarin)

How does Fioricet affect blood thinning medications? The acetaminophen component in Fioricet can potentially enhance the effects of blood thinners, increasing the risk of bleeding. Close monitoring and potential dosage adjustments may be necessary.

Interactions with Liver Enzymes

Fioricet can affect liver enzymes, potentially altering the metabolism of other drugs, including:

• Doxycycline
• Estrogen
• Felodipine
• Quinidine
• Rilpivirine
• Tamoxifen
• Certain beta-blockers and corticosteroids

How does Fioricet’s effect on liver enzymes impact other medications? By speeding up the removal of these drugs from the body, Fioricet may reduce their effectiveness. Healthcare providers may need to adjust dosages or consider alternative treatments.

Proper Dosing and Administration of Fioricet

Correct dosing of Fioricet is crucial for both efficacy and safety. The typical dosage for adults is one or two tablets every four hours as needed, not to exceed six tablets per day.

Factors Affecting Dosage

Several factors may influence the appropriate Fioricet dosage:

• Age
• Weight
• Liver function
• Kidney function
• Other medications being taken
• Severity of headache symptoms

Why is it important not to exceed the recommended dosage? Exceeding the recommended dosage can increase the risk of side effects, particularly liver damage due to the acetaminophen component. It can also lead to dependence on the barbiturate component.

Special Dosing Considerations

Certain populations may require special dosing considerations:

• Elderly patients: May require lower doses due to increased sensitivity
• Patients with liver impairment: May need dose reduction or alternative treatments
• Patients with a history of substance abuse: May require closer monitoring or alternative treatments

How should patients approach Fioricet use if they have special health conditions? Patients with pre-existing health conditions or those in special population groups should consult their healthcare provider for personalized dosing instructions and monitoring plans.

Precautions and Warnings for Fioricet Use

While Fioricet can be an effective treatment for headaches, it comes with several important precautions and warnings that patients and healthcare providers should be aware of.

Risk of Dependence and Withdrawal

The barbiturate component of Fioricet (butalbital) carries a risk of physical and psychological dependence, especially with prolonged use or high doses.

• Signs of dependence may include:
  • Needing increased doses for the same effect
  • Experiencing withdrawal symptoms when stopping the medication
  • Continued use despite negative consequences
• Withdrawal symptoms can include:
  • Anxiety
  • Muscle twitching
  • Tremor
  • Weakness
  • Dizziness
  • Nausea and vomiting

How can patients minimize the risk of dependence on Fioricet? Using the medication exactly as prescribed, avoiding prolonged use, and discussing any concerns about dependence with a healthcare provider are crucial steps in minimizing this risk.

Liver Toxicity Concerns

The acetaminophen component of Fioricet can cause liver damage if taken in high doses or combined with other acetaminophen-containing products.

• Symptoms of liver toxicity may include:
  • Yellowing of the skin or eyes (jaundice)
  • Dark urine
  • Abdominal pain
  • Nausea and vomiting

Why is it crucial to monitor total acetaminophen intake? Patients should be aware of all sources of acetaminophen in their medications and ensure they do not exceed the maximum recommended daily dose of 4000 mg from all sources combined.

Pregnancy and Breastfeeding Considerations

Fioricet use during pregnancy and breastfeeding requires careful consideration:

• Pregnancy: Fioricet is generally not recommended during pregnancy, especially in the first trimester, due to potential risks to the fetus.
• Breastfeeding: The components of Fioricet can pass into breast milk and may affect a nursing infant.

What should pregnant or breastfeeding women do if they require headache treatment? They should consult their healthcare provider to discuss safer alternative treatments or carefully weigh the potential benefits and risks of Fioricet use.

Alternatives to Fioricet for Headache Management

While Fioricet can be effective for many patients, its potential for dependence and side effects may lead some to seek alternatives. Several other options exist for managing headaches and migraines:

Non-Pharmacological Approaches

• Stress management techniques (e.g., meditation, yoga)
• Regular exercise
• Adequate sleep hygiene
• Dietary modifications (identifying and avoiding trigger foods)
• Acupuncture
• Biofeedback

Can non-pharmacological approaches be as effective as medication? For some patients, these methods can be highly effective in reducing the frequency and intensity of headaches, either alone or in combination with medication.

Alternative Medications

Several other medication classes can be used for headache management:

• Triptans (e.g., sumatriptan, rizatriptan) for migraines
• Non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen
• Beta-blockers or calcium channel blockers for prevention
• Antidepressants (e.g., amitriptyline) for chronic headaches
• Anti-epileptic drugs (e.g., topiramate) for migraine prevention

How do healthcare providers determine the best alternative treatment? The choice of alternative treatment depends on the type and frequency of headaches, the patient’s overall health, potential side effects, and individual response to different therapies.

Emerging Therapies

Research into headache management continues to yield new treatment options:

• CGRP antagonists for migraine prevention and treatment
• Neuromodulation devices
• Botulinum toxin injections for chronic migraines

What promise do these emerging therapies hold for headache sufferers? These newer treatments offer hope for patients who haven’t found relief with traditional therapies, potentially providing more targeted and effective headache management with fewer side effects.

In conclusion, while Fioricet remains a valuable tool in the management of certain types of headaches, it’s essential for patients and healthcare providers to weigh its benefits against potential risks and consider the full spectrum of available treatment options. Personalized treatment plans, careful monitoring, and open communication between patients and their healthcare team are key to achieving optimal headache management while minimizing risks.

Butalbital Compound Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

Some products that may interact with this drug include: acetazolamide, darunavir, dichlorphenamide, ketorolac, lithium, 6-mercaptopurine, methotrexate, methoxyflurane, mifepristone, phenytoin, sodium oxybate, certain antibiotics (including penicillin, sulfonamides such as sulfamethoxazole), certain drugs used to treat gout (including uricosuric drugs such as probenecid, sulfinpyrazone).

This medication may increase the risk of bleeding when taken with other drugs that also may cause bleeding. Examples include anti-platelet drugs such as clopidogrel, “blood thinners” such as dabigatran/enoxaparin/warfarin, among others.

This drug can speed up the removal of other drugs from your body by affecting certain liver enzymes. These affected drugs include doxycycline, estrogen, felodipine, lonafarnib, quinidine, rilpivirine, tamoxifen, theophylline, voriconazole, certain beta blockers (such as metoprolol), corticosteroids (such as prednisone), among others.

Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana (cannabis), other drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine).

Check the labels on all your medicines (allergy or cough-and-cold products, other headache medications) because they may contain aspirin, caffeine, or ingredients that cause drowsiness. Also keep in mind that certain beverages (such as coffee, colas, tea) contain caffeine. Ask your pharmacist about using those products safely.

Also, check all prescription and nonprescription medicine labels carefully since many medications contain pain relievers/fever reducers (NSAIDs such as ibuprofen, naproxen, aspirin) that may increase your risk for side effects if taken together with this medication. However, if your doctor has directed you to take low-dose aspirin to prevent heart attack or stroke (usually 81-162 milligrams a day), you should continue taking the aspirin unless your doctor instructs you otherwise. Ask your doctor or pharmacist for more details.

This medication may decrease the effectiveness of hormonal birth control such as pills, patch, or ring. This could cause pregnancy. Discuss with your doctor or pharmacist if you should use additional reliable birth control methods while using this medication. Also tell your doctor if you have any new spotting or breakthrough bleeding, because these may be signs that your birth control is not working well.

This medication may interfere with certain medical/laboratory tests (including fasting blood glucose, cholesterol levels, prothrombin time, urine 5-HIAA levels, urine VMA levels, certain urine glucose tests, dipyridamole-thallium imaging tests), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

Does Butalbital Compound Tablet interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Common and Rare Side Effects for Fioricet

COMMON side effects

If experienced, these tend to have a Severe expression i

Sorry, we have no data available. Please contact your doctor or pharmacist.

If experienced, these tend to have a Less Severe expression i

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

If experienced, these tend to have a Less Severe expression i

RARE side effects

If experienced, these tend to have a Severe expression i

If experienced, these tend to have a Less Severe expression i

Full Drug Information

Free RX Coupon

Save up to 80% on your prescriptions.

Available coupons

Save up to 80% on your prescription with WebMDRx

Related Links

Drug Survey

Are you currently using Fioricet?

This survey is being conducted by the WebMD marketing sciences department.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

Today on WebMD

Butalbital, Acetaminophen, Caffeine, and Codeine

Adult Medication

Share

Provided by Lexicomp ^® , this document contains all the information you need to know about this medicine, including indications, directions for use, side effects, and when your healthcare provider should be contacted.

Trade names: USA

Fioricet/Codeine

Warning

• This medicine contains acetaminophen. During the use of acetaminophen, liver disorders were recorded. In some cases, these disorders have required liver transplantation or have resulted in death. The majority of liver problems occurred in patients taking more than 4,000 milligrams (mg) of acetaminophen per day. Often, patients used not 1, but several drugs containing acetaminophen.
• This drug is a strong pain reliever that can be habit-forming, abused or misused. Misuse or abuse of this drug can lead to overdose and death. Consult with your doctor.
• This drug can cause very bad and sometimes deadly breathing problems. Call your doctor right away if breathing is slow, shallow, or difficult.
• The risk of serious and sometimes deadly respiratory problems may be increased when this drug is started or the dose is increased.
• Even one dose of this drug, taken by another person or by mistake, can be deadly, especially in children. If this drug has been taken by another person or by mistake, get medical help right away.
• Long-term use of this drug during pregnancy may cause withdrawal symptoms in the newborn. This can be life threatening. Consult your doctor.
• This drug contains an opioid. Serious side effects have occurred when using opioids with benzodiazepines, alcohol, marijuana, or other forms of cannabis, as well as prescription or over-the-counter drugs that can cause drowsiness or slow action. These effects include slow or labored breathing and death. Benzodiazepines include drugs such as alprazolam, diazepam, and lorazepam. Benzodiazepines can be used to treat many health conditions such as anxiety, sleep disorders, or seizures. If you have any questions, please consult your doctor.
• Many drugs interact with this drug and may increase the risk of side effects such as life-threatening breathing problems. Check with your doctor and pharmacist to make sure it is safe to use this drug with all your other drugs.
• Do not take with alcohol or products containing alcohol. Dangerous, sometimes deadly, effects may develop.
• Seek immediate medical attention if you feel very drowsy, severely dizzy, or if you lose consciousness. Caregivers or others should seek immediate medical attention if the patient does not respond, does not respond, or does not respond in the usual way, or if he sleeps and does not wake up.
• This drug is not approved for use in children. Severe and sometimes fatal breathing problems have been reported with codeine in children. Most often this occurred after surgery to remove the tonsils or adenoids and in children with an accelerated codeine metabolism. Do not give to children under 12 years of age. Do not give to children under 18 who are severely overweight, have certain health problems such as sleep apnea or other lung or breathing problems, or have had surgery to remove their tonsils or adenoids. If your child has taken this drug, ask your doctor about the benefits and risks.

What is this drug used for?

• It is used to treat tension headache.

What should I tell my doctor BEFORE taking this drug?

• If you have an allergy to this drug, any of its ingredients, other drugs, foods or substances. Tell your doctor about your allergies and how they have manifested.
• If you have any of the following health conditions: Lung or breathing problems such as asthma, shortness of breath, or sleep apnea; high levels of carbon dioxide in the blood; gastrointestinal obstruction or narrowing.
• If you have porphyria.
• If you have taken medications for depression or Parkinson’s disease in the past 14 days. These include isocarboxazid, phenelzine, tranylcypromine, selegiline, or rasagiline. An episode of very high blood pressure may occur.
• If you are taking any of the following drugs: buprenorphine, butorphanol, linezolid, methylene blue, nalbuphine, or pentazocine.
• If your doctor has told you that your body metabolizes certain drugs faster.
• If you are breastfeeding. Do not breastfeed while taking this drug.

This list of drugs and conditions that may interact with this drug is not exhaustive.

Tell your doctor and pharmacist about all medicines you take (prescription and over-the-counter, natural products and vitamins) and any health problems you have. You need to make sure that this drug is safe for your conditions and in combination with other drugs you are already taking. Do not start or stop taking any drug or change the dosage without your doctor’s advice.

What do I need to know or do while taking this drug?

• Tell all your health care workers that you are taking this drug. These are doctors, nurses, pharmacists and dentists.
• Avoid driving and other activities that require increased attention until you see how this drug affects you.
• To reduce the risk of dizziness or loss of consciousness, get up slowly from a lying or sitting position. Walking up and down stairs should be done with care.
• It is not recommended to use other medicines containing acetaminophen. Carefully study the instructions for medicines. Taking acetaminophen in excessive amounts can lead to liver problems.
• Follow the instructions exactly. Do not exceed your daily dose of acetaminophen. If you are not sure what your daily dose of acetaminophen is, ask your doctor or pharmacist for it. Some people may take this drug in doses up to 4,000 milligrams (mg) per day as directed by their doctor. Some patients (eg, those with liver disease and children) require a dose reduction of acetaminophen. If you have exceeded your daily dose of acetaminophen, contact your doctor immediately, even if you do not feel worse.
• This drug may affect the results of some lab tests. Tell all your health care workers and laboratory staff that you are taking this drug.
• Be careful if you have low levels of an enzyme called glucose-6-phosphate dehydrogenase (G6PD). Anemia may occur. Low levels of G6PD are more common in patients of African, South Asian, Middle Eastern, and Mediterranean origin.
• Limit caffeine (such as tea, coffee, and cola) and chocolate. When taken with this drug, it can cause nervousness, tremors, and tachycardia.
• This drug may increase the risk of seizures in some people, including people who have had seizures in the past. Talk to your doctor to find out if your risk of seizures is increased with this drug.
• Long-term use of an opioid medicine can lead to a decrease in the level of sex hormones. If you have a decreased interest in sex, fertility problems, no menstruation, or problems with ejaculation, see your doctor.
• Taking opioids like this can cause a rare but severe adrenal disorder. If you feel very tired or weak, pass out, or have severe dizziness, severe nausea, vomiting, or loss of appetite, call your healthcare provider right away.
• Possible severe skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis). This can lead to severe health problems, which can be permanent, and sometimes death. Seek immediate medical attention if you experience symptoms such as redness, swelling of the skin with blistering or peeling (with or without fever), redness or irritation of the eyes, and sores in the mouth, throat, nose, or eyes.
• If you are 65 years of age or older, use this drug with caution. You may experience more side effects.
• Children may have a higher risk of very serious side effects. This risk may be more likely in children with respiratory failure. Some children have experienced life-threatening respiratory problems when using codeine. Consult your doctor.
• When used during pregnancy, the drug may have a harmful effect on the fetus. If you are pregnant or become pregnant while taking this drug, call your doctor right away.

What side effects should I report to my doctor immediately?

WARNING. In rare cases, this drug can cause serious and sometimes deadly side effects in some patients. Contact your doctor or seek medical attention right away if you have any of the following signs or symptoms that may be associated with serious side effects:

• Signs of an allergic reaction such as rash, hives, itching, red and swollen skin with blisters or peeling with or without fever, wheezing, tightness in the chest or throat, trouble breathing, swallowing or speaking, unusual hoarseness, swelling in the mouth, face, lips, tongue or throat. Some allergic reactions in rare cases have become life-threatening.
• Signs of liver problems such as dark urine, fatigue, lack of appetite, nausea or abdominal pain, light-colored stools, vomiting, yellowing of the skin or eyes.
• Signs of kidney problems, including not passing urine, changes in the volume of urine, blood in the urine, or rapid weight gain.
• Labored, slow or shallow breathing.
• Noisy breathing.
• Breathing disorders during sleep (sleep apnea syndrome).
• Severe dizziness or fainting.
• Confusion of consciousness.
• Severe constipation or abdominal pain. These may be signs of a severe bowel disorder.
• fever, chills, sore throat; the appearance of bruising and bleeding for unexplained reasons; pronounced feeling of tiredness or weakness.
• Mood changes.
• Seizures.
• Pain or pressure in the chest or a fast heartbeat.
• Shiver.
• Lethargy, feeling drunk, or feeling unwell.
• When this drug is taken with certain other drugs, a bad and sometimes deadly condition called serotonin syndrome can develop. Call your doctor right away if you experience agitation, balance problems, confusion, hallucinations, high fever, tachycardia or abnormal heart rhythms, flushing, muscle twitching or stiffness, seizures, tremors or tremors, excessive sweating, severe diarrhea, nausea or vomiting , severe headache.

What are some other side effects of this drug?

Any medicine can have side effects. However, for many people, side effects are either minor or non-existent. Contact your doctor or seek medical attention if these or any other side effects bother you or do not go away:

• Pain in the intestines.
• Nausea or vomiting.
• Constipation.
• Feeling dizzy, drowsy, tired or weak.
• Headache.
• Nervous tension and agitation.

This list of possible side effects is not exhaustive. If you have any questions about side effects, please contact your doctor. Talk to your doctor about side effects.

You can report side effects to the National Health Board.

You can report side effects to the FDA at 1-800-332-1088. You can also report side effects at https://www.fda.gov/medwatch.

What is the best way to take this drug?

Use this drug as directed by your doctor. Read all the information provided to you. Strictly follow all instructions.

• Take with or without food. Take with food if medicine causes nausea.
• Drink plenty of non-caffeinated fluids, unless your doctor has told you to drink less fluids.
• You should keep a diary of headaches.
• Check with your doctor if you frequently drink grapefruit juice or eat grapefruit.
• You will be closely monitored to avoid misuse, abuse, or dependence on this drug.
• If this drug is taken for a long time or at high doses, its effectiveness may be reduced and a higher dose may be needed to achieve the same effect. The so-called tolerance to the drug develops. Talk to your doctor if this drug stops working as you want. Do not take the drug in higher doses than prescribed by your doctor.
• Long-term or regular use of opioid medications like this can lead to addiction. Reducing the dose or stopping this drug suddenly can cause a serious risk of withdrawal reactions or other serious problems. Talk to your doctor before reducing your dose or stopping this drug. You must follow the doctor’s instructions. Tell your doctor if you have severe pain, mood changes, suicidal thoughts, or any other side effects.
• If you are allergic to tartrazine (dye yellow #5), talk to your doctor. Some products contain tartrazine.
• Do not take this drug with other strong pain medications or if you are using a pain patch without talking to your doctor first.

What if I miss a dose of a drug?

• If you take the drug regularly, take the missed dose as soon as you can.
• If it’s time for your next dose, don’t take the missed dose and then go back to your regular dosing schedule.
• Do not take 2 doses or an additional dose at the same time.
• In most cases, this drug is used as needed. Do not take the drug more often than prescribed by your doctor.

How do I store and/or discard this drug?

• Store at room temperature in a dry place. Do not store in the bathroom.
• Keep this medicine in a protected place out of sight and reach of children and out of the reach of other people. A box or room that is locked with a key can act as a secure storage place for the drug. Keep all medicines out of the reach of pets.
• Dispose of unused or expired drugs. Do not empty into a toilet or sewer unless instructed to do so. If you have any questions about disposing of medicines, ask your pharmacist. Drug disposal programs may be in place in your area.

General information about medicines

• If your health does not improve or even worsens, see your doctor.
• Do not give your medicine to anyone and do not take other people’s medicines.
• Some medicines may come with other patient information leaflets. If you have any questions about this drug, talk with your doctor, nurse, pharmacist, or other health care professional.
• A separate instruction for patients is attached to the drug. Please read this information carefully. Reread it each time you refill your supply. If you have any questions about this drug, ask your doctor, pharmacist, or other health care professional.
• An overdose of this drug can be treated with a medicine called naloxone. Your doctor may prescribe naloxone to keep you with you while you are taking this drug. If you have any questions about buying or using naloxone, talk to your doctor or pharmacist. If you think you have overdosed, seek medical attention immediately, even if you have taken naloxone.
• If you think you have overdosed, call a poison control center or get medical help right away. Be prepared to tell or show what drug you took, how much, and when it happened.

Consumer Use of Information and Limitation of Liability

This summary information includes a summary of the diagnosis, treatment, and/or drug product. It is not intended to be a comprehensive source of data and should be used as a tool to help the user understand and/or evaluate potential diagnostic and treatment options. It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a particular patient. It should not be considered medical advice or a substitute for medical advice, diagnosis or treatment provided by a physician based on a medical examination and assessment of the patient’s specific and unique circumstances. Patients should consult with their physician for full information about their health, medical issues, and treatment options, including any risks or benefits regarding the use of medications. This information is not a guarantee that a treatment or drug is safe, effective, or approved for a particular patient. UpToDate, Inc. and its subsidiaries disclaim any warranties or liabilities related to this information or its use. The use of this information is subject to the Terms of Use found at https://www.wolterskluwer.com/en/know/clinical-effectiveness-terms.

Last revision date

2021-03-19

Copyright

© UpToDate, Inc. and its affiliates and/or licensors, 2023. All rights reserved.

Date last updated

Monday, December 12, 2022

Is Fioricet a good option for migraines? – Drink-Drink

07.07.2022 DrinkDrinkAdmin

Contents

• What is Fioriset?
• Why is Fioricet used to treat migraines?
• How does Fioricet work for migraine?
• How do you take Fioriset?
• What are the possible side effects of taking Fioricet?
• Possible drug interactions Fioricet
• Are there any risks of taking Fioricet for migraine?
• Is it possible to overdose with Fioricet?
• What about allergic reactions to Fioriset?
• What is a migraine?
• How is Fioricet different from other migraine remedies?
  • Comparison of other available medicines
• Fioricet Precautions
• Conclusion

Migraine is a complex brain disorder that affects nearly 1 billion people globally. A migraine is more than a severe headache. This can cause debilitating effects that can persist for several days and disrupt daily life.

Fortunately, today there are many ways to relieve migraine symptoms. Medications are one of the tools along with other support options to alleviate the condition.

Fioriset is a combination medication that has been around for many years and is approved for the treatment of tension-type headache symptoms. Although it is sometimes used for migraines, there are other options.

In this article, we will discuss the uses, side effects, and other important information you need to know about Fioricet.

What is Fioriset?

Fioricet is a brand name multi-ingredient medication used to treat certain types of headaches. It is also available in generic form.

Fioriset contains:

• butalbital 50 mg
• acetaminophen 300 mg
• caffeine 40 mg , but is also prescribed off-label for migraine.

  Why is Fioricet used to treat migraines?

  Fioriset is an older drug often prescribed to treat migraine symptoms. However, there is not enough evidence to show that it is effective for migraine attacks, especially when compared to safer products.

  Although Fioricet has been used for many years for migraines, it is not approved for this use and there are more serious risks than benefits from this medication.

  Fioriset may be an option if other migraine treatments have not worked. Your doctor will just want to keep a close eye on you to avoid side effects.

  It is prescribed to relieve immediate headache symptoms, but not to prevent migraine attacks.

  How does Fioricet work to treat migraines?

  Fioricet contains three different active ingredients that work together for tension headaches. The exact mode of action of Fioricet for tension headache relief is not clear.

  Butalbital is a barbiturate that helps with relaxation and anxiety, acetaminophen acts as an analgesic to relieve pain, and caffeine also helps relieve pain.

  How do you take Fioriset?

  Fioricet is available as capsules that you take by mouth. The recommended dose is 1-2 capsules every 4 hours. Do not exceed 6 capsules in 24 hours.

  Fioriset can cause stomach upset, so taking it with food or milk may help.

  Ask your pharmacist about the best way to take Fioricet.

  What are the possible side effects of taking Fioricet?

  Share your medical history with your doctor and ask if it is safe for you to take Fioricet. Fioriset may cause some serious side effects, including:

  • confusion
  • seizure
  • Depression
  • drowsiness, dizziness
  • drunkenness
  • abdominal pain
  • dry mouth
  • heartburn
  • rapid pulse
  • muscle pain
  • rash, itching
  • vomiting

  life-threatening reaction to Fioricet, call 911 immediately.0003

  • MAO inhibitors
  • opioid painkillers
  • alcohol
  • medicines for sleep or anxiety, such as benzodiazepines cough/cold with acetaminophen

  This is not a complete list of all side effects. effects and interactions of Fioricet. Ask your pharmacist for a complete list.

  Are there any risks of taking Fioricet for migraine?

  Fioricet has several risks and may not be suitable for everyone.

  The active ingredient butalbital in Fioricet may be habit-forming. Using higher doses for a long time may lead to dependence on Fioricet. Stopping the medication abruptly after regular use can also cause withdrawal symptoms.

  Drinking alcohol or taking other sedative drugs with Fioricet may be harmful and cause dangerous side effects. Butalbital is excreted from the body for a long time.

  Do not take Fioricet with other products that have the same active ingredients. Taking too many of these ingredients together can increase the risk of overdose, cause liver or kidney damage, and can be life-threatening.

  Talk to your doctor about any medications and over-the-counter products you are taking, including vitamins, herbs, and natural supplements.

  Some examples include:

  • acetaminophen (Tylenol, multi-symptom cough/cold)
  • caffeine (energy drinks, migraine excedrin, caffeine tablets)
  • butalbital (barbiturates)

  Regular use of Fioricet may increase the risk of rebound headaches or medication-related headaches. Migraine Prevalence and Prevention in America The Cabinet found that butalbital use for 5 days per month increases the risk of acute migraine becoming chronic.

  Fioriset may increase blood pressure and heart rate. If you have a history of high blood pressure or heart disease, ask your doctor about the risks of Fioriset.

  Is it possible to overdose with Fioricet?

  Yes, it is possible to overdose Fioricet. Always take your medicine exactly as prescribed by your doctor. Taking too much Fioricet can be dangerous and even life-threatening.

  If you think you’ve taken too much Fioricet, call 911 (or your local emergency number) or go to the emergency room to get help right away.

  Some overdose symptoms may include:

  • drowsiness, dizziness
  • nausea, vomiting
  • confusion
  • slow breathing
  • coma
  • severe drowsiness
  • drop in temperature body
  • problems with coordination and balance

  What about allergic reactions to Fioriset?

  Avoid Fioricet if you are allergic to any of the ingredients of this medicine.

  Symptoms of an allergic reaction may include:

  • rash
  • itching
  • swelling
  • difficulty breathing
  • Difficulty swallowing

  The acetaminophen in Fioricet may cause severe allergic reactions or anaphylaxis in some people. Tell your doctor if you have ever had a reaction to acetaminophen in the past.

  Do not take more than 4000 mg of acetaminophen per day as this may cause liver damage. Seek immediate medical attention if you have taken more than 4000 mg of acetaminophen.

  If you have liver problems, Fioriset may not be right for you. Talk to your doctor about your medical history.

  Abrupt discontinuation of Fioricet after taking high doses for a long time may cause withdrawal symptoms.

  Withdrawal symptoms include:

  • depression, anxiety
  • anxiety
  • Difficulty sleeping
  • hallucinations
  • heart problems
  • fever
  • nausea and vomiting
  • stomach cramps
  • seizures

  when to seek emergency care

  Seek emergency medical attention right away if you experience any – any of these symptoms while taking Fioricet:

  • sudden severe headache
  • fever
  • confusion
  • torticollis
  • seizures
  • difficulty speaking

  This may be a sign of a serious medical problem.

  What is a migraine?

  Migraine affects nearly 30 million Americans and affects more women. Migraine can be inherited.

  They are also different from tension headaches, another common type of headache.

  Symptoms of a migraine attack can sometimes include aura, throbbing pain, sensitivity to light or sound, nausea, vomiting, which usually affects one side of the head but can affect both sides. Symptoms can last from hours to days, interfering with daily life.

  Some possible migraine triggers may include:

  • stress
  • lack of sleep
  • hunger
  • hormonal changes
  • weather changes

  Your doctor diagnoses migraine b Based on your symptoms, medical history, and other diagnostic tests such as an MRI .

  How is Fioricet different from other migraine remedies?

  Migraine prescription drugs fall into two categories: those that help prevent a migraine attack and those that treat acute symptoms.

  There are also over-the-counter medicines that can help relieve headaches.

  Because there are many migraine medications, ask your doctor about your options.

  The cost of drugs depends on whether they are branded or generic, whether you have insurance, which pharmacy you use, and other factors.

  Comparison of other available drugs

  Brand	Fioricet	Ubrelva	Imitrex	Ravoe	Aimovig 9049 7
  Generic name	Butalbital 50 mg/acetaminophen 300 mg/caffeine 40 mg	ubrogepant	sumatriptan	lasmiditan	erenumab
  Total	Yes	no	no
  *Costs (depends on brand or generic and insurance)	generic about $10-12 for 30 capsules	expensive without insurance	generic about 10 -$20 for 9 tablets	expensive without insurance	expensive without insurance
  Authorized use	tension headache	migraine attack	migraine attack	migraine attack and	migraine prophylaxis
  Side effects mouth, nausea, drowsiness, fatigue	chest, neck pain	serotonin syndrome, dizziness, numbness, fatigue, tingling, drowsiness, rebound migraine	constipation, high blood pressure, injection site reactions
  How is it taken?	oral	oral	nasal spray, injection, nasal powder	oral	Injection pens
  Is there a risk of withdrawal while taking the medication?	Yes	No	No	No	No

  0299

  Fioriset is not safe for people with porphyria, skin and nervous system disorders.

  Fioricet may cause drowsiness, dizziness or fatigue, and these effects may last for several hours. Avoid driving or performing any task that requires mental concentration or alertness. Talk to your doctor about the risks of Fioricet and how it may affect your daily activities.

  Drinking alcohol together with Fioricet may increase the sedative side effects. Too much alcohol with Fioricet can also increase the risk of liver damage and toxicity.

  Fioricet may not be right for you if you have certain health problems or conditions.

  • history of depression, psychiatric disorders, suicidal thoughts
  • history of substance use disorder
  • breathing problems such as asthma, lung disease and emphysema
  • kidney, liver or stomach problems 900 06
  • old age
  • pregnant or breastfeeding

  Conclusion

  Migraine can be a serious problem for many because it disrupts daily life. Today, there are many treatment options.