What is Flausiver and how does it work. What are the potential side effects of Flausiver. How should Flausiver be taken for optimal results. What precautions should be considered when using Flausiver. How does Flausiver interact with other medications. What is the recommended dosage for Flausiver. What do user reviews say about Flausiver effectiveness.

Understanding Flausiver: A Powerful Bioflavonoid

Flausiver, also known as hesperidin, is a plant-derived chemical classified as a bioflavonoid. Primarily found in citrus fruits, this compound has garnered attention for its potential medicinal properties. Researchers have been exploring its effects on various health conditions, particularly those related to blood vessel function and inflammation.

How does Flausiver work in the body? Flausiver is believed to enhance blood vessel function and reduce inflammation. These properties make it a subject of interest for treating conditions like hemorrhoids, varicose veins, and poor circulation. Its ability to influence vascular health has led to its use in both preventive and therapeutic contexts.

The Natural Sources of Flausiver

While Flausiver is available as a supplement, it’s naturally present in several foods. Which fruits contain the highest concentrations of Flausiver? Citrus fruits are the primary natural sources, including:

• Oranges
• Lemons
• Limes
• Grapefruits

Incorporating these fruits into your diet can provide a natural boost of Flausiver, along with other beneficial nutrients and antioxidants.

Potential Health Benefits of Flausiver

Research into Flausiver has revealed several potential health benefits, particularly in the realm of vascular health. What conditions might Flausiver help alleviate? Let’s explore some of the most promising applications:

Chronic Venous Insufficiency (CVI)

Chronic venous insufficiency is a condition characterized by poor circulation in the legs, often leading to swelling and discomfort. How effective is Flausiver in treating CVI? Studies suggest that taking a product containing Flausiver (hesperidin methyl chalcone), butcher’s broom, and vitamin C can significantly relieve CVI symptoms. Additionally, a combination of Flausiver and diosmin taken for 2-6 months has shown improvements in CVI symptoms, although some research indicates that the drug Venoruton might be more effective.

Hemorrhoids

Hemorrhoids can be a painful and uncomfortable condition affecting many individuals. Can Flausiver provide relief for hemorrhoid sufferers? Research indicates that a combination of Flausiver and diosmin may improve symptoms of anal hemorrhoids. Furthermore, this combination might help prevent recurrence after healing and could be beneficial during acute flare-ups.

Venous Leg Ulcers

Venous leg ulcers, often caused by poor circulation, can be challenging to treat. How does Flausiver contribute to the healing process? Studies show that taking a specific product containing Flausiver and diosmin orally for two months can enhance the healing of small venous stasis ulcers when used in conjunction with compression dressings.

Potential Side Effects and Safety Considerations

While Flausiver shows promise in treating various conditions, it’s essential to be aware of potential side effects and safety concerns. What should users know about the safety profile of Flausiver?

Flausiver is considered possibly safe for most people when taken orally for up to six months. However, there’s insufficient data on its long-term safety beyond this period. Users should be aware of potential side effects, which may include:

• Stomach pain and upset
• Diarrhea
• Headache

It’s crucial to consult with a healthcare provider before starting any new supplement regimen, especially if you have pre-existing health conditions or are taking other medications.

Special Precautions for Specific Groups

Certain groups should exercise additional caution when considering Flausiver supplementation. Who should be particularly careful with Flausiver use?

1. Pregnant and breastfeeding women: While Flausiver is possibly safe when taken with diosmin, consult a healthcare provider before use.
2. Individuals with bleeding disorders: Flausiver might slow blood clotting, potentially exacerbating bleeding issues.
3. People with low blood pressure: Flausiver may lower blood pressure further, requiring careful monitoring.
4. Those undergoing surgery: Due to its potential effects on blood clotting, it’s advisable to stop taking Flausiver at least two weeks before scheduled surgery.

Flausiver Interactions: What You Need to Know

Understanding how Flausiver interacts with other medications is crucial for safe and effective use. What are the most important drug interactions to be aware of?

Moderate Interactions

Several medications have been identified as having moderate interactions with Flausiver:

• Celiprolol: Flausiver may reduce absorption, potentially decreasing its effectiveness.
• Diltiazem: Similar to celiprolol, Flausiver might reduce absorption and efficacy.
• Blood pressure medications: Combining Flausiver with antihypertensive drugs could lead to excessively low blood pressure.
• Medications metabolized by cellular pumps: Flausiver might affect the activity of these pumps, potentially altering the absorption of certain drugs.

Always inform your healthcare provider about all medications and supplements you’re taking to avoid potential interactions.

Dosing Guidelines for Flausiver

Determining the right dosage of Flausiver is essential for maximizing benefits while minimizing risks. How should Flausiver be taken for optimal results?

The appropriate dosage of Flausiver can vary depending on the specific condition being treated and individual factors. Some general guidelines include:

• For chronic venous insufficiency: 500-600 mg of hesperidin combined with 900-1000 mg of diosmin daily, divided into 2-3 doses.
• For hemorrhoids: A typical dose might involve 500 mg of hesperidin with 900 mg of diosmin, taken twice daily for 4 days, followed by once daily for 3 days.

It’s important to note that these are general recommendations, and individual needs may vary. Always consult with a healthcare professional to determine the most appropriate dosage for your specific situation.

User Reviews and Experiences with Flausiver

Understanding real-world experiences can provide valuable insights into the effectiveness of Flausiver. What do users say about their experiences with this supplement?

User reviews of Flausiver have been mixed, with many reporting positive outcomes for vascular health issues:

• Some users with chronic venous insufficiency report reduced leg swelling and discomfort.
• Individuals using Flausiver for hemorrhoids often note faster relief and reduced recurrence.
• Some users with varicose veins have reported improved appearance and reduced discomfort.

However, it’s important to remember that individual experiences can vary, and not all users may experience the same benefits. Some users report minimal or no noticeable effects, while others may experience side effects.

Factors Influencing User Experiences

Several factors can influence an individual’s experience with Flausiver:

1. Dosage and duration of use
2. Specific health condition being treated
3. Individual metabolism and body chemistry
4. Concurrent use of other medications or supplements
5. Overall health and lifestyle factors

When considering user reviews, it’s essential to keep these factors in mind and consult with a healthcare professional for personalized advice.

The Future of Flausiver Research

As interest in natural compounds for health applications continues to grow, what does the future hold for Flausiver research? Scientists are exploring several promising avenues:

Expanding Applications

Researchers are investigating the potential of Flausiver in treating additional health conditions. Areas of interest include:

• Cardiovascular health: Exploring Flausiver’s effects on heart health and blood pressure regulation.
• Metabolic disorders: Investigating potential benefits for conditions like diabetes and metabolic syndrome.
• Cognitive function: Examining Flausiver’s antioxidant properties and their potential impact on brain health.

Improved Formulations

Scientists are working on developing more bioavailable forms of Flausiver to enhance its absorption and efficacy. This could lead to lower required doses and potentially fewer side effects.

Combination Therapies

Research is ongoing into how Flausiver might synergize with other compounds or treatments to provide enhanced benefits for various health conditions.

As research progresses, our understanding of Flausiver’s potential benefits and optimal use is likely to evolve, potentially opening up new therapeutic possibilities.

Integrating Flausiver into a Healthy Lifestyle

While Flausiver shows promise in addressing specific health concerns, it’s important to consider it as part of a broader approach to health and wellness. How can Flausiver be integrated into a healthy lifestyle?

Dietary Considerations

Incorporating Flausiver-rich foods into your diet can be a natural way to increase intake. Consider the following tips:

• Add citrus fruits to your daily meal plan
• Try using citrus zest in cooking for an extra flavor and nutrient boost
• Experiment with citrus-based salad dressings or marinades

Complementary Lifestyle Practices

To maximize the potential benefits of Flausiver, consider combining it with other healthy lifestyle practices:

1. Regular exercise: Particularly beneficial for improving circulation and vascular health
2. Adequate hydration: Supports overall circulatory function
3. Balanced diet: Rich in fruits, vegetables, and whole grains to support overall health
4. Stress management: Practices like meditation or yoga can complement vascular health efforts

Remember, while Flausiver may offer specific health benefits, it’s most effective when used as part of a comprehensive approach to health and wellness.

Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews

Overview

Hesperidin is a plant chemical that is classified as a “bioflavonoid.” It is most commonly found in citrus fruits. People use it as medicine.

Hesperidin, alone or in combination with other citrus bioflavonoids (such as diosmin), is most commonly used for blood vessel conditions such as hemorrhoids, varicose veins, and poor circulation (venous stasis).

Hesperidin may help blood vessels function better. It may also reduce inflammation.

Uses & Effectiveness ?

Possibly Effective for

• Poor circulation that can cause the legs to swell (chronic venous insufficiency or CVI). Taking a particular product containing hesperidin methyl chalcone, butcher’s broom, and vitamin C by mouth seems to relieve the symptoms of poor circulation in the legs. Also, taking a different product containing hesperidin and diosmin by mouth for 2-6 months seems to improve CVI symptoms, although taking the drug Venoruton might be more effective for treating this condition.
• Hemorrhoids. Some research suggests that taking hesperidin and diosmin improves symptoms of anal hemorrhoids. It may also prevent hemorrhoids from coming back after they have healed and may help in an emergency worsening of hemorrhoids.
• Leg sores caused by weak blood circulation (venous leg ulcer). Taking a specific product containing hesperidin and diosmin by mouth for 2 months seems to improve the healing of small venous stasis ulcers when used along with compression dressings.

Possibly Ineffective for

• High cholesterol. Most research shows that taking hesperidin doesn’t improve cholesterol levels.
• Obesity. Some research shows that taking glucosyl hesperidin for 12 weeks doesn’t reduce body weight in people that are slightly overweight.

Side Effects

When taken by mouth: Hesperidin is POSSIBLY SAFE for most people when taken by mouth for up to 6 months. There isn’t enough information to know if hesperidin is safe when taken for longer than 6 months. Side effects include stomach pain and upset, diarrhea, and headache.

Special Precautions and Warnings

When taken by mouth: Hesperidin is POSSIBLY SAFE for most people when taken by mouth for up to 6 months. There isn’t enough information to know if hesperidin is safe when taken for longer than 6 months. Side effects include stomach pain and upset, diarrhea, and headache. Pregnancy and breast-feeding: Hesperidin is POSSIBLY SAFE for pregnant or breast-feeding women when taken by mouth with diosmin.

Bleeding disorder: Hesperidin might slow blood clotting and increase the risk of bleeding. In theory, hesperidin might make bleeding disorders worse.

Low blood pressure: Hesperidin might lower blood pressure. In theory, taking hesperidin might make blood pressure become too low in people who already have low blood pressure.

Surgery: Hesperidin might prolong bleeding. There is concern that hesperidin might increase the risk of bleeding during and after surgical procedures. Stop taking hesperidin at least 2 weeks before a scheduled surgery.

Interactions ?

Moderate Interaction

Be cautious with this combination

• Hesperidin may reduce how much celiprolol the body absorbs. This might decrease how well celiprolol works. Do not take hesperidin with celiprolol.

• Hesperidin may reduce how much diltiazem the body absorbs. This might decrease how well diltiazem works. Do not take diltiazem with hesperidin.

• Hesperidin might decrease blood pressure. Taking hesperidin along with medications used to lower high blood pressure might cause your blood pressure to go too low.

  Some medications for high blood pressure include nifedipine (Adalat, Procardia), verapamil (Calan, Isoptin, Verelan), diltiazem (Cardizem), isradipine (DynaCirc), felodipine (Plendil), amlodipine (Norvasc), and others.

• Some medications are moved by pumps in cells. Hesperidin might make these pumps less active and increase the amount of some medications that get absorbed by the body. This might increase the amount of some medications in the body, which could lead to more side effects. But there is not enough information to know if this is a big concern.

  Some medications that are moved by these pumps include etoposide, paclitaxel, vinblastine, vincristine, vindesine, ketoconazole, itraconazole, amprenavir, indinavir, nelfinavir, saquinavir, cimetidine, ranitidine, diltiazem, verapamil, corticosteroids, erythromycin, cisapride (Propulsid), fexofenadine (Allegra), cyclosporine, loperamide (Imodium), quinidine, and others.

• Hesperidin might slow blood clotting. Taking hesperidin along with medications that also slow blood clotting might increase the risk of bruising and bleeding and others.

• Hesperidin might cause sleepiness and drowsiness. Medications that cause sleepiness are called sedatives. Taking hesperidin along with sedative medications might cause too much sleepiness. Taking hesperidin along with sedative medications used in surgery might cause prolonged sedation.

  Some sedative medications include pentobarbital (Nembutal), phenobarbital (Luminal), secobarbital (Seconal), thiopental (Pentothal), fentanyl (Duragesic, Sublimaze), morphine, propofol (Diprivan), and others.

• Hesperidin may increase how much verapamil the body absorbs. This might increase the effects and side effects of verapamil. Do not take verapamil with hesperidin.

Dosing

The following doses have been studied in scientific research:

ADULTS

BY MOUTH:

• For poor circulation that can cause the legs to swell (chronic venous insufficiency or CVI): A specific combination product containing hesperidin methyl chalcone 150 mg, butcher’s broom root extract 150 mg, and ascorbic acid 100 mg has been used. Also, a combination of 100-150 mg of hesperidin with 900-1350 mg of diosmin taken daily for 2-6 months has been used.
• For hemorrhoids: A combination of 150 mg of hesperidin plus 1350 mg of diosmin twice daily for 4 days, followed by 100 mg of hesperidin and 900 mg of diosmin twice daily for 3 days has been used. Also, a combination of 50 mg of hesperidin plus 450 mg of diosmin twice daily for 3 months has been used to prevent the return of hemorrhoids.
• For sores caused by weak blood circulation (venous leg ulcer): A combination of 100 mg of hesperidin and 900 mg of diosmin daily for up to 2 months has been used.

View References

CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2020.

Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews

Overview

Diosmin is a chemical in some plants. It’s found mainly in citrus fruits.

Diosmin is most often used for hemorrhoids and leg sores caused by poor blood flow. It’s also used for other conditions, but there’s no strong evidence to support these uses.

Diosmin is often taken with hesperidin. Hesperidin is another plant chemical.

Diosmin might work by reducing swelling (inflammation) and restoring normal vein function. Diosmin also seems to have antioxidant effects.

Uses & Effectiveness ?

Possibly Effective for

• Hemorrhoids. Taking diosmin in high doses along with hesperidin seems to reduce symptoms of hemorrhoids. Taking diosmin in lower doses along with hesperidin plus troxerutin also seems to help. Taking diosmin in lower doses along with hesperidin seems to help prevent hemorrhoids from coming back.
• Leg sore caused by weak blood circulation (venous leg ulcer). Taking diosmin with hesperidin and using compression dressing seems to help heal leg ulcers caused by poor circulation.

Insufficient Evidence for

• Back pain. Early research shows that taking diosmin for at least 8 weeks decreases pain and might reduce the need to use rescue pain medicine similarly to receiving the standard medications mannitol and dexamethasone.
• Poor circulation that can cause the legs to swell (chronic venous insufficiency or CVI). Some research shows that taking diosmin may help to reduce pain by a small amount in people with CVI. But not all research agrees.
• Swelling in the arms or legs caused by damage to the lymph system (lymphedema). Taking diosmin with hesperidin might not reduce swelling of the arms following surgery for breast cancer.
• Minor bleeding.
• Bleeding gums.
• Bleeding (hemorrhage) in the eye.
• Preventing damage to the liver.
• Varicose veins.
• Other conditions.

More evidence is needed to rate the effectiveness of diosmin for these uses.

Side Effects

When taken by mouth: Diosmin is POSSIBLY SAFE for most people when used by mouth short-term. It can cause some side effects such as stomach pain, diarrhea, dizziness, headache, skin redness and hives, muscle pain, blood problems, and altered heart rate.

Special Precautions and Warnings

When taken by mouth: Diosmin is POSSIBLY SAFE for most people when used by mouth short-term. It can cause some side effects such as stomach pain, diarrhea, dizziness, headache, skin redness and hives, muscle pain, blood problems, and altered heart rate. Pregnancy and breast-feeding: Not enough is known about the use of diosmin during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Bleeding disorders: Diosmin might make bleeding disorders worse. If you have a bleeding disorder, don’t use diosmin.

Interactions ?

Moderate Interaction

Be cautious with this combination

• The body breaks down chlorzoxazone (Parafon Forte, Paraflex) to get rid of it. Diosmin might decrease how quickly the body breaks down chlorzoxazone (Parafon Forte, Paraflex). Taking diosmin along with chlorzoxazone (Parafon Forte, Paraflex) might increase the effects and side effects of chlorzoxazone (Parafon Forte, Paraflex).

• The body breaks down diclofenac (Voltaren, others) to get rid of it. Diosmin might decrease how quickly the body breaks down diclofenac (Voltaren, others). Taking diosmin along with diclofenac (Voltaren, others) might increase the effects and side effects of diclofenac (Voltaren, others).

• Some medications are changed and broken down by the liver. Diosmin might decrease how quickly the liver breaks down some medications. Taking diosmin along with some medications that are broken down by the liver might increase the effects and side effects of these medications. Before taking diosmin, talk to your healthcare provider if you take any medications that are changed by the liver.
  
  
  Some medications that are changed by the liver include celecoxib (Celebrex), diclofenac (Voltaren), fluvastatin (Lescol), glipizide (Glucotrol), ibuprofen (Advil, Motrin), irbesartan (Avapro), losartan (Cozaar), phenytoin (Dilantin), piroxicam (Feldene), tamoxifen (Nolvadex), tolbutamide (Tolinase), torsemide (Demadex), warfarin (Coumadin), and others.

• Some medications are changed and broken down by the liver. Diosmin might decrease how quickly the liver breaks down some medications. Taking diosmin along with some medications that are broken down by the liver may increase the effects and side effects of these medications.
  
  
  Some medications changed by the liver include acetaminophen, chlorzoxazone (Parafon Forte), ethanol, theophylline, and anesthetics such as enflurane (Ethrane), halothane (Fluothane), isoflurane (Forane), and methoxyflurane (Penthrane).

• Some medications are moved by pumps in cells. Diosmin might make these pumps less active and increase the amount of some medications that get absorbed by the body. This might increase the amount of some medications in the body, which could lead to more side effects.
  
  
  Some medications that are moved by these pumps include some chemotherapeutic agents (etoposide, paclitaxel, vinblastine, vincristine, vindesine), antifungals (ketoconazole, itraconazole), protease inhibitors (amprenavir, indinavir, nelfinavir, saquinavir), h3 antagonists (cimetidine, ranitidine), some calcium channel blockers (diltiazem, verapamil), corticosteroids, erythromycin, cisapride (Propulsid), fexofenadine (Allegra), cyclosporine, loperamide (Imodium), quinidine, and others.

• Diosmin might slow blood clotting. Taking diosmin along with medications that also slow blood clotting might increase the chances of bruising and bleeding.
  
  Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.

• The body breaks down carbamazepine (Tegretol) to get rid of it. Diosmin might decrease how quickly the body breaks down carbamazepine (Tegretol). Taking diosmin along with carbamazepine (Tegretol) might increase the effects and side effects of carbamazepine (Tegretol).

• Some medications including fexofenadine (Allegra) are moved by pumps in cells. Diosmin might make these pumps less active and increase how much of some medications get absorbed by the body. This might cause more side effects from some medications.

• Some medications are changed and broken down by the liver. Diosmin may decrease how quickly the liver breaks down some medications. Taking diosmin along with some medications may increase the effects and side effects of these medications. Before taking diosmin, talk to your health care provider if you are taking any medications that are changed by the liver.

  Some medications changed by the liver include lovastatin (Mevacor), ketoconazole (Nizoral), itraconazole (Sporanox), clarithromycin (Biaxin), erythromycin, cyclosporine (Neoral, Sandimmune), amlodipine (Norvasc), verapamil (Calan, Isoptin), diltiazem (Cardizem), estrogens, indinavir (Crixivan), fexofenadine (Allegra), triazolam (Halcion), alprazolam (Xanax), and many others.

Dosing

Diosmin is often taken in combination with hesperidin.

The following doses have been studied in scientific research:

ADULTS

BY MOUTH:

• For hemorrhoids: For treating hemorrhoids, 1350 mg of diosmin plus 150 mg of hesperidin twice daily for 4 days followed by 900 mg of diosmin and 100 mg of hesperidin twice daily for 3 days has been used. Also, 300 mg of diosmin, 300 mg of troxerutin, and 300 mg of hesperidin three times daily for 3 days, followed by two times daily for 2 days, and then once daily for 7 days has been used. Thereafter, 300 mg of diosmin, 300 mg of troxerutin, and 100 mg of hesperidin has been used daily for one month. Some researchers also try 600 mg of diosmin three times daily for 4 days, followed by 300 mg twice daily for 10 days, in combination with 11 grams of psyllium daily. However, this lower diosmin dose does not seem to be as effective.
• For leg ulcers caused by poor circulation (venous stasis ulcers): 900 mg of diosmin plus 100 mg of hesperidin daily has been used for up to 2 months.

View References

CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances.