Hdl ldl ratio chart. HDL vs LDL Cholesterol: Understanding Ratios, Levels, and Health Implications
What is the difference between HDL and LDL cholesterol. How do cholesterol ratios affect heart health. What are optimal cholesterol levels for adults and children. How does age and gender influence cholesterol levels. What lifestyle changes can improve cholesterol profile.
The Basics of Cholesterol: HDL vs LDL
Cholesterol is a fatty substance produced by the liver and found in certain foods. While the body requires some cholesterol to function properly, an excess of the wrong type can lead to serious health issues. Understanding the difference between HDL (high-density lipoprotein) and LDL (low-density lipoprotein) cholesterol is crucial for maintaining good heart health.
HDL cholesterol is often referred to as “good” cholesterol because it helps remove other forms of cholesterol from the bloodstream. In contrast, LDL cholesterol is known as “bad” cholesterol because it can build up in the arteries, increasing the risk of heart disease and stroke.
What are triglycerides?
Triglycerides are another type of fat in the blood that contribute to total cholesterol levels. High triglyceride levels, combined with high LDL and low HDL cholesterol, can significantly increase the risk of heart disease.
Decoding Cholesterol Levels: What the Numbers Mean
To interpret cholesterol test results, it’s essential to understand the ideal ranges for different components:
- Total cholesterol: Less than 200 mg/dL is considered good
- HDL cholesterol: 60 mg/dL or higher is ideal
- LDL cholesterol: Less than 100 mg/dL is optimal
- Triglycerides: Less than 150 mg/dL is desirable
These values can vary slightly depending on age, gender, and individual risk factors. Regular cholesterol checks are recommended for adults every 4 to 6 years, starting at age 20.
The HDL/LDL Ratio: A Key Indicator of Heart Health
While individual cholesterol numbers are important, the ratio of HDL to LDL cholesterol provides valuable insight into overall heart health. A higher ratio of HDL to LDL is generally associated with better cardiovascular health.
How is the HDL/LDL ratio calculated?
The HDL/LDL ratio is calculated by dividing the HDL cholesterol level by the LDL cholesterol level. For example, if someone has an HDL of 50 mg/dL and an LDL of 100 mg/dL, their HDL/LDL ratio would be 0.5.
A ratio above 0.3 is considered good, with higher ratios indicating better cardiovascular health. However, it’s important to note that this ratio should be considered alongside individual cholesterol levels and other risk factors.
Age and Gender: How They Influence Cholesterol Levels
Cholesterol levels naturally tend to rise with age, but the impact can differ between men and women. Men generally have a higher risk of elevated cholesterol levels throughout their lives. However, women’s risk increases significantly after menopause due to hormonal changes.
Do women need different cholesterol levels than men?
Yes, there are slight differences in ideal cholesterol levels for men and women. Women typically need higher levels of HDL cholesterol than men for optimal heart health. The recommended minimum HDL level for women is 50 mg/dL, while for men it’s 40 mg/dL.
Cholesterol in Children: When to Start Monitoring
Contrary to popular belief, high cholesterol isn’t just an adult concern. Children can also develop unhealthy cholesterol levels, especially if they have risk factors such as obesity, diabetes, or a family history of high cholesterol.
Current guidelines recommend cholesterol screening for all children between ages 9-11 and again between 17-21. For children with additional risk factors, earlier and more frequent testing may be advised.
What are healthy cholesterol levels for children?
Ideal cholesterol levels for children are slightly different from those for adults:
- Total cholesterol: Less than 170 mg/dL
- HDL cholesterol: Greater than 45 mg/dL
- LDL cholesterol: Less than 110 mg/dL
- Triglycerides: Less than 75-90 mg/dL, depending on age
Lifestyle Factors Affecting Cholesterol Levels
While some factors influencing cholesterol levels, such as age and genetics, are beyond our control, many lifestyle choices can significantly impact cholesterol profiles.
How does diet affect cholesterol levels?
Diet plays a crucial role in managing cholesterol. Foods high in saturated and trans fats can increase LDL cholesterol, while foods rich in omega-3 fatty acids and soluble fiber can help lower it. Incorporating more fruits, vegetables, whole grains, and lean proteins into your diet can positively affect your cholesterol levels.
Can exercise improve cholesterol?
Regular physical activity can have a significant impact on cholesterol levels. Exercise helps increase HDL cholesterol while lowering LDL cholesterol and triglycerides. Aim for at least 150 minutes of moderate-intensity aerobic activity or 75 minutes of vigorous-intensity aerobic activity per week.
Managing High Cholesterol: Treatment Options
For individuals with high cholesterol, treatment options may include lifestyle changes, medication, or a combination of both. The appropriate approach depends on individual risk factors and overall health status.
What medications are used to treat high cholesterol?
Several types of medications can help lower cholesterol levels:
- Statins: These drugs block a substance your liver needs to make cholesterol.
- Bile acid sequestrants: These medications help remove cholesterol from the bloodstream.
- Cholesterol absorption inhibitors: These drugs reduce the amount of cholesterol absorbed from food.
- PCSK9 inhibitors: These newer injectable medications can dramatically lower LDL cholesterol.
It’s important to consult with a healthcare provider to determine the most appropriate treatment plan based on individual circumstances.
The Future of Cholesterol Management: Emerging Research and Technologies
As our understanding of cholesterol and its impact on health continues to evolve, new approaches to management and treatment are emerging. Researchers are exploring innovative therapies and diagnostic tools to improve cholesterol control and reduce cardiovascular risk.
What new cholesterol treatments are on the horizon?
Several promising developments in cholesterol management are being studied:
- Gene editing techniques to reduce cholesterol production
- Novel drugs targeting specific proteins involved in cholesterol metabolism
- Personalized medicine approaches based on genetic profiles
- Advanced imaging techniques for early detection of arterial plaque
These advancements hold the potential to revolutionize how we approach cholesterol management and cardiovascular disease prevention in the future.
Understanding the intricacies of cholesterol, including the HDL/LDL ratio and its implications for heart health, is crucial for maintaining overall well-being. By staying informed about cholesterol levels, adopting heart-healthy lifestyle habits, and working closely with healthcare providers, individuals can take proactive steps to manage their cholesterol and reduce their risk of cardiovascular disease. As research continues to unveil new insights and treatment options, the future of cholesterol management looks promising, offering hope for improved heart health outcomes across all age groups.
By age, LDL, HDL, and More
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- Evaluate ingredients and composition: Do they have the potential to cause harm?
- Fact-check all health claims: Do they align with the current body of scientific evidence?
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Recommended total cholesterol levels are under 200 milligrams per deciliter (mg/dL) for most adults and under 170 mg/dL for children. Women typically need more HDL (good cholesterol) than men.
Good heart health is like a building block: It’s cumulative. This is particularly true when it comes to high cholesterol.
Cholesterol is a fatty substance your liver makes. It’s also found in certain foods. Your body needs some cholesterol to function properly. But having too much of the bad type of cholesterol — low-density lipoprotein (LDL) — puts you at risk for having a heart attack or stroke.
According to the Centers for Disease Control and Prevention (CDC), having high cholesterol raises your risk for heart disease.
Sex and gender exist on spectrums. This article will use the terms “men,” “women,” or both to refer to sex assigned at birth. Click here to learn more.
Your total cholesterol level is the overall amount of cholesterol found in your blood. It consists of:
- low-density lipoproteins (LDLs)
- high-density lipoproteins (HDLs)
- triglycerides
LDL is also called “bad” cholesterol because it blocks your blood vessels and increases your risk for heart disease. HDL is considered “good” cholesterol because it helps protect you from heart disease. The higher your HDL, the better.
Total cholesterol also includes a triglyceride count. These are another type of fat that can build up in the body and are considered the “building blocks” of cholesterol.
High levels of triglycerides and low levels of HDL raise your risk for heart disease.
The American Heart Association recommends that all adults have their cholesterol checked every 4 to 6 years, starting at age 20, which is when cholesterol levels can start to rise.
As we age, cholesterol levels tend to climb. Men are generally at a higher risk than women for higher cholesterol. However, a woman’s risk goes up after she enters menopause.
For those with high cholesterol and other cardiac risk factors, such as diabetes, more frequent testing is recommended.
Cholesterol chart for adults
According to the 2018 guidelines on the management of blood cholesterol published in the Journal of the American College of Cardiology (JACC), these are the acceptable, borderline, and high measurements for adults.
All values are in mg/dL (milligrams per deciliter) and are based on fasting measurements.
Total cholesterol | HDL cholesterol | LDL cholesterol | Triglycerides | |
---|---|---|---|---|
Good | Less than 200 (but the lower the better) | Ideal is 60 or higher; 40 or higher for men and 50 or higher for women is acceptable | Less than 100; below 70 if coronary artery disease is present | Less than 149; ideal is |
Borderline to moderately elevated | 200–239 | n/a | 130–159 | 150–199 |
High | 240 or higher | 60 or higher | 160 or higher; 190 considered very high | 200 or higher; 500 considered very high |
Low | n/a | less than 40 for men and less than 50 for women | n/a | n/a |
Cholesterol levels in men vs.
women
Generally, guidelines are similar for men and women over the age of 20, though they differ when it comes to HDL cholesterol, as seen above. Women should aim for higher levels of HDL cholesterol.
Children who are physically active, eat a nutrient-dense diet, are not overweight, and do not have a family history of high cholesterol are at a lower risk for having high cholesterol.
Current guidelines recommend that all children have their cholesterol checked between ages 9 and 11 years, and then again between ages 17 and 21 years.
Children with more risk factors, such as having diabetes, obesity, or a family history of high cholesterol, should be checked between ages 2 and 8 years, and again between ages 12 and 16 years.
Cholesterol chart for children
According to the JACC, the following are the recommended cholesterol levels for children:
All values are in mg/dL:
Total cholesterol | HDL cholesterol | LDL cholesterol | Triglycerides | |
---|---|---|---|---|
Good | 170 or less | Greater than 45 | Less than 110 | Less than 75 in children 0–9; less than 90 in children 10–19 |
Borderline | 170–199 | 40-45 | 110–129 | 75–99 in children 0–9; 90–129 in children 10–19 |
High | 200 or higher | n/a | 130 or higher | 100 or more in children 0–9; 130 or more in children 10–19 |
Low | n/a | Less than 40 | n/a | n/a |
Your doctor may recommend a plan of treatment for high cholesterol that includes lifestyle modifications and potentially medication. This will vary based on factors like other medications you may be taking, your age, sex, and general health.
Here are some medications more commonly prescribed for high cholesterol:
- Statins. Statins lower the LDL cholesterol levels by slowing the production of cholesterol by the liver.
- Bile acid sequestrants. Bile acid sequestrants are substances used in digestion. These resins can reduce cholesterol levels in the blood by binding to bile acids and removing them, forcing the body to break down LDL cholesterol to create bile acids instead.
- Cholesterol absorption inhibitors. Cholesterol absorption inhibitors can block the absorption of cholesterol from the diet, sometimes in conjunction with statins.
- Bempedoic acid. Bempedoic acid helps to stop an enzyme in the liver, ATP citrate lyase, from making cholesterol. This drug is often combined with statins for increased benefit for those with familial hypercholesterolemia, an inherited condition that can cause early heart disease.
- PCSK9 inhibitors. Also used frequently with familial hypercholesterolemia, PCSK9 inhibitors, which are injected drugs, help the liver absorb and remove more LDL cholesterol from the blood.
Medications can also be used to treat contributing factors to cholesterol like triglycerides. These may be used in addition to some of the medications above.
“One misconception is that people can have poorly controlled cholesterol for years and then decide to take action. By then the plaque could already have built up,” says Dr. Eugenia Gianos, director of cardiovascular prevention for Northwell Health in New York.
The good news is that lifestyle changes are reasonably effective in helping you reduce cholesterol levels. They’re also fairly straightforward and can be done at any age and within most abilities.
- Exercise if you can. Physical activity can help you lose weight and boost your HDL cholesterol. Aim for 30 to 60 minutes a day of moderate cardiovascular exercise, such as biking, jogging, swimming, and dancing, at least 5 times a week.
- Eat more fiber. Try to add more fiber to your diet, such as replacing white bread and pasta with whole grains.
- Eat healthy fats: Healthy fats include olive oil, avocado, and certain nuts. These are all fats that won’t raise your LDL levels.
- Limit your saturated-fat intake. Reduce the amount of high-saturated fatty foods like cheese, whole milk, and high-fat red meats.
- Limit red and processed meats, sodium and sugar-sweetened foods. A heart healthy diet focuses on fruits, vegetables, whole grains, poultry, fish and nuts, while limiting processed meats, excess sodium, and added sugar.
- If you smoke, consider quitting. Smoking decreases HDL cholesterol. Quitting can help you better manage your cholesterol levels.
- Limit your alcohol intake. The American Heart Association recommends drinking alcohol in moderation, which means, on average, no more than two drinks per day for men and no more than one drink per day for women.
Drinking too much alcohol can raise levels of triglyceride fats in the bloodstream and lead to conditions such as hypertension (high blood pressure) and atrial fibrillation.
- Get to a healthy-for-you weight. Losing excess body weight can help lower your cholesterol levels.
- Check your levels. You can see a doctor or use an at-home test kit to check your cholesterol levels. You can purchase a testing kit online from LetsGetChecked here.
There are few noticeable symptoms of high cholesterol. Emergency symptoms such as a stroke or heart attack may be the only indicator of damage from high cholesterol. This means that regular monitoring by a doctor is essential.
Most people should get their cholesterol checked with a blood test every 4 to 6 years. Your doctor may recommend more frequent screening if you live with any of the following:
- a history of heart conditions
- family history of high cholesterol
- high blood pressure
- if you smoke
- have overweight or obesity
Read this article in Spanish.
By age, LDL, HDL, and More
We include products we think are useful for our readers. If you buy through links on this page, we may earn a small commission Here’s our process.
Healthline only shows you brands and products that we stand behind.
Our team thoroughly researches and evaluates the recommendations we make on our site. To establish that the product manufacturers addressed safety and efficacy standards, we:
- Evaluate ingredients and composition: Do they have the potential to cause harm?
- Fact-check all health claims: Do they align with the current body of scientific evidence?
- Assess the brand: Does it operate with integrity and adhere to industry best practices?
We do the research so you can find trusted products for your health and wellness.
Read more about our vetting process.
Was this helpful?
Recommended total cholesterol levels are under 200 milligrams per deciliter (mg/dL) for most adults and under 170 mg/dL for children. Women typically need more HDL (good cholesterol) than men.
Good heart health is like a building block: It’s cumulative. This is particularly true when it comes to high cholesterol.
Cholesterol is a fatty substance your liver makes. It’s also found in certain foods. Your body needs some cholesterol to function properly. But having too much of the bad type of cholesterol — low-density lipoprotein (LDL) — puts you at risk for having a heart attack or stroke.
According to the Centers for Disease Control and Prevention (CDC), having high cholesterol raises your risk for heart disease.
Sex and gender exist on spectrums. This article will use the terms “men,” “women,” or both to refer to sex assigned at birth. Click here to learn more.
Your total cholesterol level is the overall amount of cholesterol found in your blood. It consists of:
- low-density lipoproteins (LDLs)
- high-density lipoproteins (HDLs)
- triglycerides
LDL is also called “bad” cholesterol because it blocks your blood vessels and increases your risk for heart disease. HDL is considered “good” cholesterol because it helps protect you from heart disease. The higher your HDL, the better.
Total cholesterol also includes a triglyceride count. These are another type of fat that can build up in the body and are considered the “building blocks” of cholesterol.
High levels of triglycerides and low levels of HDL raise your risk for heart disease.
The American Heart Association recommends that all adults have their cholesterol checked every 4 to 6 years, starting at age 20, which is when cholesterol levels can start to rise.
As we age, cholesterol levels tend to climb. Men are generally at a higher risk than women for higher cholesterol. However, a woman’s risk goes up after she enters menopause.
For those with high cholesterol and other cardiac risk factors, such as diabetes, more frequent testing is recommended.
Cholesterol chart for adults
According to the 2018 guidelines on the management of blood cholesterol published in the Journal of the American College of Cardiology (JACC), these are the acceptable, borderline, and high measurements for adults.
All values are in mg/dL (milligrams per deciliter) and are based on fasting measurements.
Total cholesterol | HDL cholesterol | LDL cholesterol | Triglycerides | |
---|---|---|---|---|
Good | Less than 200 (but the lower the better) | Ideal is 60 or higher; 40 or higher for men and 50 or higher for women is acceptable | Less than 100; below 70 if coronary artery disease is present | Less than 149; ideal is |
Borderline to moderately elevated | 200–239 | n/a | 130–159 | 150–199 |
High | 240 or higher | 60 or higher | 160 or higher; 190 considered very high | 200 or higher; 500 considered very high |
Low | n/a | less than 40 for men and less than 50 for women | n/a | n/a |
Cholesterol levels in men vs.
women
Generally, guidelines are similar for men and women over the age of 20, though they differ when it comes to HDL cholesterol, as seen above. Women should aim for higher levels of HDL cholesterol.
Children who are physically active, eat a nutrient-dense diet, are not overweight, and do not have a family history of high cholesterol are at a lower risk for having high cholesterol.
Current guidelines recommend that all children have their cholesterol checked between ages 9 and 11 years, and then again between ages 17 and 21 years.
Children with more risk factors, such as having diabetes, obesity, or a family history of high cholesterol, should be checked between ages 2 and 8 years, and again between ages 12 and 16 years.
Cholesterol chart for children
According to the JACC, the following are the recommended cholesterol levels for children:
All values are in mg/dL:
Total cholesterol | HDL cholesterol | LDL cholesterol | Triglycerides | |
---|---|---|---|---|
Good | 170 or less | Greater than 45 | Less than 110 | Less than 75 in children 0–9; less than 90 in children 10–19 |
Borderline | 170–199 | 40-45 | 110–129 | 75–99 in children 0–9; 90–129 in children 10–19 |
High | 200 or higher | n/a | 130 or higher | 100 or more in children 0–9; 130 or more in children 10–19 |
Low | n/a | Less than 40 | n/a | n/a |
Your doctor may recommend a plan of treatment for high cholesterol that includes lifestyle modifications and potentially medication. This will vary based on factors like other medications you may be taking, your age, sex, and general health.
Here are some medications more commonly prescribed for high cholesterol:
- Statins. Statins lower the LDL cholesterol levels by slowing the production of cholesterol by the liver.
- Bile acid sequestrants. Bile acid sequestrants are substances used in digestion. These resins can reduce cholesterol levels in the blood by binding to bile acids and removing them, forcing the body to break down LDL cholesterol to create bile acids instead.
- Cholesterol absorption inhibitors. Cholesterol absorption inhibitors can block the absorption of cholesterol from the diet, sometimes in conjunction with statins.
- Bempedoic acid. Bempedoic acid helps to stop an enzyme in the liver, ATP citrate lyase, from making cholesterol. This drug is often combined with statins for increased benefit for those with familial hypercholesterolemia, an inherited condition that can cause early heart disease.
- PCSK9 inhibitors. Also used frequently with familial hypercholesterolemia, PCSK9 inhibitors, which are injected drugs, help the liver absorb and remove more LDL cholesterol from the blood.
Medications can also be used to treat contributing factors to cholesterol like triglycerides. These may be used in addition to some of the medications above.
“One misconception is that people can have poorly controlled cholesterol for years and then decide to take action. By then the plaque could already have built up,” says Dr. Eugenia Gianos, director of cardiovascular prevention for Northwell Health in New York.
The good news is that lifestyle changes are reasonably effective in helping you reduce cholesterol levels. They’re also fairly straightforward and can be done at any age and within most abilities.
- Exercise if you can. Physical activity can help you lose weight and boost your HDL cholesterol. Aim for 30 to 60 minutes a day of moderate cardiovascular exercise, such as biking, jogging, swimming, and dancing, at least 5 times a week.
- Eat more fiber. Try to add more fiber to your diet, such as replacing white bread and pasta with whole grains.
- Eat healthy fats: Healthy fats include olive oil, avocado, and certain nuts. These are all fats that won’t raise your LDL levels.
- Limit your saturated-fat intake. Reduce the amount of high-saturated fatty foods like cheese, whole milk, and high-fat red meats.
- Limit red and processed meats, sodium and sugar-sweetened foods. A heart healthy diet focuses on fruits, vegetables, whole grains, poultry, fish and nuts, while limiting processed meats, excess sodium, and added sugar.
- If you smoke, consider quitting. Smoking decreases HDL cholesterol. Quitting can help you better manage your cholesterol levels.
- Limit your alcohol intake. The American Heart Association recommends drinking alcohol in moderation, which means, on average, no more than two drinks per day for men and no more than one drink per day for women.
Drinking too much alcohol can raise levels of triglyceride fats in the bloodstream and lead to conditions such as hypertension (high blood pressure) and atrial fibrillation.
- Get to a healthy-for-you weight. Losing excess body weight can help lower your cholesterol levels.
- Check your levels. You can see a doctor or use an at-home test kit to check your cholesterol levels. You can purchase a testing kit online from LetsGetChecked here.
There are few noticeable symptoms of high cholesterol. Emergency symptoms such as a stroke or heart attack may be the only indicator of damage from high cholesterol. This means that regular monitoring by a doctor is essential.
Most people should get their cholesterol checked with a blood test every 4 to 6 years. Your doctor may recommend more frequent screening if you live with any of the following:
- a history of heart conditions
- family history of high cholesterol
- high blood pressure
- if you smoke
- have overweight or obesity
Read this article in Spanish.
Calculation of the coefficient of atherogenicity – Clinic 1
Coefficient of atherogenicity – an indicator that reflects the degree of risk of developing diseases of the heart and blood vessels.
Atherogenic coefficient – the ratio of “bad” cholesterol to “good”, characterizing the risk of developing cardiovascular diseases.
Cholesterol (CH) is a fat-like substance vital for the body. It is involved in the formation of cell membranes of all organs and tissues of the body. Based on cholesterol, hormones are created, without which growth, development of the body and the implementation of the reproduction function are impossible. Bile acids are formed from it, due to which fats are absorbed in the intestines.
Cholesterol is insoluble in water, therefore, in order to move around the body, it is “packed” into a shell consisting of special proteins – apoproteins. The resulting complex (“cholesterol + apoprotein”) is called lipoprotein. Several types of lipoproteins circulate in the blood, differing in the proportions of their components:
- very low density lipoproteins (VLDL),
- low density lipoproteins (LDL),
- high density lipoproteins (HDL).
LDL and VLDL are considered “bad” types of cholesterol, as they contribute to the formation of plaque in the arteries, which can lead to a heart attack or stroke. HDL, on the other hand, is called “good” cholesterol because it removes excess amounts of low-density cholesterol from vessel walls.
In the development of atherosclerotic plaques in the vessels, not only the increase in the total amount of cholesterol in the blood, but also the ratio between “bad” and “good” cholesterol is important. This is what the coefficient of atherogenicity reflects. It is calculated using the following formula: CA = (total cholesterol – HDL) / HDL.
Thus, in order to determine CA, it is necessary to know the level of total cholesterol and HDL.
The atherogenic coefficient equal to 2-3 is considered optimal.
The atherogenic index is a guide value. For a more accurate assessment of the risk of developing atherosclerosis and diseases of the heart and blood vessels, it is better to use the exact values of total cholesterol, LDL and HDL.
What is research used for?
The atherogenic index test is used to assess the risk of atherosclerosis and heart and vascular problems.
Changes in the levels of “bad” and “good” cholesterol and their ratio in itself, as a rule, do not manifest any symptoms, so their timely determination is very important in the prevention of cardiovascular diseases.
When is the test ordered?
Atherogenic coefficient is usually part of the lipid profile, as are total cholesterol, HDL, LDL, VLDL and triglycerides. A lipid profile may be part of a routine screening routine or more frequently if the person is on a low-fat diet and/or is taking lipid-lowering medications. In these cases, it is checked whether the patient reaches the target level of cholesterol values and, accordingly, whether his risk of cardiovascular diseases is reduced.
In addition, a lipid profile is prescribed more often if there are risk factors for the development of cardiovascular diseases in the patient’s life:
- smoking,
- in men over 45 years of age, in women over 55,
- high blood pressure (140/90 mmHg and above),
- high cholesterol or cardiovascular disease in family members (heart attack or stroke in a male relative under 55 years of age or a woman under 65 years of age),
- ischemic heart disease, myocardial infarction or stroke,
- diabetes,
- overweight,
- alcohol abuse,
- ingestion of large amounts of food containing animal fats,
- low physical activity.
If a child is diagnosed with high cholesterol or heart disease, it is recommended that the first lipid profile or total cholesterol test be done between the ages of 2 and 10 years.
Calculation of the coefficient of atherogenicity
Analysis of the atherogenic index in the medical center “Health”
Biomaterial: Blood serum
Deadline (in the laboratory): 1 w.d.
* The site indicates the maximum possible time for the study. It reflects the time of the study in the laboratory and does not include the time for the delivery of the biomaterial to the laboratory. The information provided is for reference only and is not a public offer. For up-to-date information, contact the Contractor’s medical center or call-center.
Lipids (fats). Substances necessary for a living organism. The main lipid that a person receives from food, and from which their own lipids are then formed, is cholesterol. It is part of cell membranes, maintains their strength. Steroid hormones are synthesized from it: hormones of the adrenal cortex that regulate water-salt and carbohydrate metabolism, sex hormones, bile acids are formed, which are involved in the absorption of fats in the intestine. In the skin under the action of sunlight, vitamin D is synthesized from cholesterol, which is necessary for the absorption of calcium.
Various complexes of lipids with proteins circulating in the blood are formed in the liver from cholesterol: high, low and very low density lipoproteins (HDL, LDL, VLDL), between which total cholesterol is divided. Low and very low density lipoproteins are deposited in plaques and contribute to the progression of atherosclerosis. High-density lipoproteins contribute to the “pulling” of cholesterol from plaques and play a protective role, stop the development of atherosclerosis. Therefore, to assess the risk of atherosclerosis and control, not only the total level of cholesterol, but also the ratio of its fractions is important. Based on these data is calculated.
Atherogenic index. Total blood cholesterol is an important, but still insufficient indicator for judging the violation of cholesterol metabolism, assessing the risk of early development of atherosclerosis, and judging the success of treatment. As part of total cholesterol, several fractions are distinguished, of which two are necessary for establishing the correct diagnosis and prognosis. For a reliable diagnosis of disorders of cholesterol metabolism, it is sufficient to determine total cholesterol (TC) and HDL (high density lipoproteins). Based on these data, the Atherogenic Index is calculated – the main indicator by which one can reliably judge the degree of lipid metabolism disorders and the likelihood of developing atherosclerosis. The value of the atherogenic index can be used to monitor the effectiveness of therapy and diet.
Indications for prescription
To diagnose pathologies of the cardiovascular system, in particular atherosclerosis, doctors prescribe a comprehensive examination. One of its components is the lipid profile. With this study, it seems possible to evaluate lipid metabolism in the human body. The study contains many indicators, one of them is the coefficient of atherogenicity (CA). If this indicator is increased in a person’s blood, a more detailed examination should be performed. Every person who has problems with fat metabolism should know what the atherogenic index is, as well as how to determine and decipher this figure. Indications for the appointment: diagnosis of atherosclerosis and monitoring the effectiveness of the treatment; control of lipid metabolism in overweight people; annual preventive examination in people over 40 years of age.
Interpretation of results/Information for specialists
The norm for a healthy person should not exceed 3-3.5. Values above 3.5-4 indicate an excess of “bad” cholesterol and the risk of developing atherosclerosis. The atherogenic index below the norm (less than 3) has no clinical significance. Along with IA, you need to know other indicators. When calculating the coefficient of atherogenicity, deviations can directly vary both upward and downward. When the atherogenic index does not exceed normal values or its level is below normal, the probability of occurrence of cardiovascular pathology tends to zero. At the level of atherogenic number exceeding 4, the probability of occurrence of ischemic changes in vital organs, thrombosis significantly increases. An atherogenic index of more than 5 indicates the presence of atherosclerotic changes in the vascular bed. In the case when an increase in the coefficient of atherogenicity is detected during the examination, measures must be taken immediately. The primary role for the normalization of the indicator is played by an anti-atherogenic diet. Allocate the main reasons that contribute to the increase in the coefficient: Poor nutrition. Diabetes mellitus with excess body weight or obesity. Bad addictions. Diseases of the liver and thyroid gland.