What are the common causes of burning sensations in legs. How can burning leg pain be effectively treated. What symptoms often accompany a burning feeling in the legs. When should you see a doctor for leg burning.

Recognizing Burning Leg Sensations: Symptoms and Associated Conditions

A burning sensation in the legs can be an alarming and uncomfortable experience. This symptom may manifest in various ways and can be accompanied by other sensations that signal underlying health issues. Understanding these symptoms is crucial for proper diagnosis and treatment.

Common Symptoms Accompanying Burning Legs

• Paresthesia (tingling sensations)
• Numbness in affected areas
• Discoloration of the skin
• Itching or irritation
• Pain or discomfort during movement

Do these symptoms always indicate a serious condition? Not necessarily. While some cases of burning legs can be attributed to temporary factors like intense exercise or minor injuries, persistent or severe symptoms may point to more complex health issues that require medical attention.

Unraveling the Causes: From Simple Explanations to Complex Conditions

The etiology of burning leg sensations can range from everyday occurrences to serious medical conditions. Identifying the root cause is essential for determining the appropriate course of treatment.

Common Causes of Burning Legs

1. Exposure to extreme temperatures
2. Overexertion during physical activities
3. Minor injuries or trauma
4. Contact with irritants or toxic substances

Can more serious conditions cause burning sensations in the legs? Indeed, several medical conditions can lead to this symptom:

Medical Conditions Associated with Burning Legs

• Meralgia paresthetica
• Venous reflux (venous insufficiency)
• Peripheral neuropathy
• Multiple sclerosis (MS)

Understanding these conditions can help patients and healthcare providers pinpoint the underlying cause of burning leg sensations and develop an appropriate treatment plan.

Meralgia Paresthetica: When Nerves Become Compressed

Meralgia paresthetica is a condition characterized by compression of the lateral femoral cutaneous nerve, which provides sensation to the outer thigh. This compression can lead to a burning sensation, numbness, and tingling in the affected area.

Identifying Meralgia Paresthetica

How can you recognize meralgia paresthetica? The primary symptom is a burning pain on the surface of the outer thigh, often accompanied by:

• Tingling sensations
• Numbness in the affected area
• Increased sensitivity to touch
• Pain that worsens with prolonged standing or walking

Is meralgia paresthetica a chronic condition? In most cases, it’s not. Many people experience full recovery within four to six weeks with appropriate treatment and lifestyle modifications.

Venous Reflux: When Blood Flow Goes Awry

Venous reflux, also known as venous insufficiency, occurs when the veins in the legs fail to properly circulate blood back to the heart. This condition can lead to a variety of symptoms, including a burning sensation in the legs.

Understanding Venous Reflux Symptoms

What are the telltale signs of venous reflux? Besides a hot or burning sensation, patients may experience:

• Swelling in the legs and ankles
• Skin discoloration, particularly around the ankles
• Itching or irritation of the skin
• Leg pain that worsens when standing
• Visible varicose veins

Can venous reflux lead to more serious complications? If left untreated, venous reflux can progress and lead to skin ulcers, deep vein thrombosis, and other vascular issues. Early diagnosis and treatment are crucial for preventing these complications.

Peripheral Neuropathy: When Nerves Misfire

Peripheral neuropathy refers to damage or dysfunction of the peripheral nerves, which can result in a range of symptoms, including burning sensations in the legs. This condition can be caused by various factors, including diabetes, alcohol use disorder, and certain medications.

Recognizing Peripheral Neuropathy Symptoms

How does peripheral neuropathy manifest in the legs? Common symptoms include:

• Burning or tingling sensations
• Numbness or reduced sensation
• Shooting or stabbing pain
• Muscle weakness
• Changes in skin texture or temperature

Is peripheral neuropathy always painful? While pain is a common symptom, some individuals may experience only numbness or tingling. The severity and type of symptoms can vary depending on the underlying cause and the nerves affected.

Multiple Sclerosis: When the Nervous System is Under Attack

Multiple sclerosis (MS) is an autoimmune condition that affects the central nervous system. Among its many symptoms, MS can cause sensory disturbances, including burning sensations in the legs.

MS-Related Burning Sensations

Why do some MS patients experience burning legs? This symptom is often the result of faulty nerve signals caused by MS lesions in the spinal cord and brain. Other sensory symptoms associated with MS include:

• Numbness or tingling in the extremities
• Electric shock-like sensations, especially when bending the neck (Lhermitte’s sign)
• Hypersensitivity to touch or temperature
• Muscle spasms or stiffness

Are burning sensations in MS constant? The intensity and frequency of these symptoms can vary greatly among individuals and may fluctuate over time. Some people experience intermittent episodes, while others may have more persistent symptoms.

Diagnosing the Cause: When to Seek Medical Attention

Given the wide range of potential causes for burning leg sensations, it’s important to know when to consult a healthcare professional. While some cases may resolve on their own, persistent or severe symptoms warrant medical evaluation.

Red Flags: When to See a Doctor

What symptoms indicate the need for immediate medical attention? Consider seeking help if you experience:

• Severe or persistent burning sensations
• Weakness or loss of function in the legs
• Burning accompanied by swelling or skin changes
• Symptoms that interfere with daily activities
• Burning sensations associated with other neurological symptoms

How will a doctor diagnose the cause of burning legs? The diagnostic process may include:

1. A thorough medical history and physical examination
2. Blood tests to check for underlying conditions like diabetes
3. Nerve conduction studies and electromyography (EMG)
4. Imaging tests such as MRI or CT scans
5. Vascular studies for suspected venous insufficiency

By identifying the root cause, healthcare providers can develop an appropriate treatment plan tailored to the individual’s needs.

Treatment Approaches: Tailoring Solutions to the Cause

The treatment of burning leg sensations varies depending on the underlying cause. From conservative measures to more invasive interventions, a range of options is available to address this symptom and its associated conditions.

Conservative Treatment Options

What are some initial treatment approaches for burning legs? Conservative measures often include:

• Over-the-counter pain relievers (e.g., acetaminophen, ibuprofen)
• Lifestyle modifications (e.g., weight loss, avoiding prolonged standing)
• Physical therapy and exercise programs
• Compression stockings for venous insufficiency
• Topical treatments like capsaicin cream

Are these treatments effective for all cases of burning legs? While conservative approaches can provide relief for many individuals, more severe or persistent cases may require additional interventions.

Advanced Treatment Options

What treatments are available for more complex cases? Advanced treatment options may include:

• Prescription medications (e.g., antidepressants, anticonvulsants)
• Corticosteroid injections
• Sclerotherapy or endovenous thermal ablation for venous reflux
• Surgical decompression for severe meralgia paresthetica
• Disease-modifying therapies for multiple sclerosis

How long does it take to see improvement with these treatments? The timeline for improvement can vary widely depending on the underlying condition and the chosen treatment approach. Some patients may experience relief within weeks, while others may require longer-term management.

Living with Burning Leg Sensations: Coping Strategies and Lifestyle Modifications

While medical treatments play a crucial role in managing burning leg sensations, lifestyle modifications and coping strategies can significantly improve quality of life for those affected by this symptom.

Lifestyle Adjustments for Symptom Management

What daily habits can help alleviate burning leg sensations? Consider incorporating these strategies:

• Regular exercise to improve circulation and nerve health
• Stress reduction techniques like meditation or yoga
• Dietary modifications to support overall health
• Proper foot care and wearing comfortable, supportive footwear
• Using cold or heat therapy as recommended by a healthcare provider

Can dietary changes impact burning leg sensations? In some cases, yes. A balanced diet rich in vitamins and minerals, particularly B vitamins, can support nerve health. Additionally, limiting alcohol intake and maintaining good blood sugar control can be beneficial for those with neuropathy.

Emotional and Psychological Support

How does chronic pain impact mental health? Living with persistent burning leg sensations can take an emotional toll. It’s important to address the psychological aspects of chronic pain, which may include:

• Seeking support from mental health professionals
• Joining support groups for individuals with similar conditions
• Practicing mindfulness and relaxation techniques
• Engaging in hobbies and activities that bring joy and distraction

By addressing both the physical and emotional aspects of burning leg sensations, individuals can develop a comprehensive approach to managing their symptoms and improving their overall well-being.

Preventing Burning Leg Sensations: Proactive Measures for Long-Term Health

While not all cases of burning leg sensations can be prevented, there are steps individuals can take to reduce their risk and maintain optimal leg health.

Lifestyle Choices for Leg Health

What preventive measures can help maintain healthy legs? Consider incorporating these habits:

• Regular exercise to promote circulation and maintain a healthy weight
• Avoiding prolonged periods of sitting or standing
• Wearing properly fitting shoes and avoiding high heels
• Maintaining good posture to reduce pressure on nerves
• Staying hydrated to support overall vascular health

Can certain exercises specifically benefit leg health? Yes, exercises that promote circulation and strengthen the legs can be particularly beneficial. These may include:

1. Walking or jogging
2. Swimming or water aerobics
3. Cycling
4. Yoga or stretching routines
5. Leg-specific strength training exercises

By incorporating these preventive measures and maintaining a healthy lifestyle, individuals can take proactive steps to reduce their risk of developing conditions that lead to burning leg sensations.

The Future of Treatment: Emerging Therapies and Research

As medical science advances, new treatments and therapies for conditions causing burning leg sensations are continually being developed and studied. These emerging approaches offer hope for improved symptom management and potentially even cures for underlying conditions.

Promising Areas of Research

What new treatments are on the horizon for burning leg sensations? Some promising areas of research include:

• Gene therapy for neuropathic conditions
• Stem cell treatments for nerve regeneration
• Advanced neuromodulation techniques
• Targeted drug delivery systems
• Novel pharmacological agents for pain management

How might these emerging therapies change the landscape of treatment? As research progresses, we may see more personalized and effective treatments that address the root causes of burning leg sensations, rather than just managing symptoms. This could lead to improved outcomes and quality of life for those affected by these conditions.

While burning leg sensations can be a challenging and sometimes debilitating symptom, understanding the underlying causes and available treatment options is crucial for effective management. By working closely with healthcare providers, adopting healthy lifestyle habits, and staying informed about emerging therapies, individuals experiencing burning leg sensations can take steps towards relief and improved overall well-being. As research continues to advance, the future holds promise for even better solutions to this complex symptom.

Burning Legs: Symptoms, Causes, and Treatments

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A feeling of burning in your legs can happen with exposure to extreme temperatures or another health condition, including some that affect the nerves. You may experience additional symptoms.

A burning sensation in your legs may have an obvious explanation, like a leg injury or during or after intense exercise. It could also be the result of damage or exposure to extreme heat, cold, or a toxic substance.

A burning feeling in your legs can often be accompanied by:

• paresthesia (tingling)
• numbness

Some reasons for a burning feeling in your legs aren’t as obvious and need a doctor’s diagnosis. These conditions include:

Meralgia paresthetica

Meralgia paresthetica occurs when the nerve that provides sensation to the skin on your thigh is compressed. It’s also referred to as Bernhardt-Roth syndrome.

The condition often presents as a burning pain on the surface of your outer thigh. The outer thigh may also tingle or feel numb.

Venous reflux

Venous reflux occurs when the veins in the leg aren’t properly circulating blood to the heart. It’s also referred to as venous insufficiency.

If a leg vein fails, the blood can back up, pool, and leak into the leg tissue. This leads to a hot or burning sensation often accompanied by discoloration and itching.

Peripheral neuropathy

Peripheral neuropathy is a loss of function of the nerves that relay signals from the body to the spinal cord and brain. It’s often associated with:

• diabetes
• alcohol use disorder
• Guillain-Barré syndrome

Multiple sclerosis (MS)

Symptoms of MS include sensory disturbances that can lead to burning pain as well as numbness and tingling in the legs. These symptoms are often the result of faulty nerve signals due to MS lesions in the spinal cord and brain.

Treatment of burning legs depends on the underlying cause.

Meralgia paresthetica

Most people can expect a full recovery from meralgia paresthetica in four to six weeks. First-line treatments can include the following:

• Drugs like aspirin, acetaminophen (Tylenol), naproxen (Aleve), or ibuprofen (Advil) can relieve pain. Shop online for acetaminophen, naproxen, or ibuprofen.
• Lose weight if you’re overweight.
• Wear loose-fitting clothing.
• Physical therapy can build leg strength.

If your pain is severe or symptoms continue for more than eight weeks, your doctor might recommend the following to reduce pain:

• corticosteroid injections
• tricyclic antidepressants
• antiseizure medications, such as gabapentin (Neurontin), phenytoin (Dilantin), or pregabalin (Lyrica)

Surgery to decompress the nerve might be recommended if you’re pain is very severe and persistent, but this is rare.

Venous reflux

Your doctor may recommend the following when venous reflux is diagnosed early:

• Compression stockings put pressure on your legs to help move blood. Find compression stockings online.
• Get moving. Avoid standing or sitting for long periods to reduce pressure on your legs. Exercise also helps pump blood.
• Blood thinners can prevent the formation of blood clots.

If the condition has progressed, your doctor might recommend a procedure to close a problem vein. Doing so forces blood to flow through healthier veins. These procedures include:

• Sclerotherapy. Your doctor injects a scarring solution to close the affected vein.
• Endovenous thermal ablation. A laser or high-frequency radio waves are focused on the problem vein and closes it.
• Ligation. Your doctor cuts and ties off the affected vein.

Peripheral neuropathy

Treatments for peripheral neuropathy can include:

• Pain relief. Over-the-counter pain medications, such as nonsteroidal anti-inflammatory drugs, can ease mild symptoms. Stronger painkillers might be prescribed for more severe symptoms.
• Antiseizure medications. Developed to treat epilepsy, antiseizure medications such as gabapentin (Neurontin) and pregabalin (Lyrica) may relieve nerve pain.
• Topical treatments. Capsaicin cream may relieve your symptoms if you’re looking for a natural option. Purchase capsaicin cream online.
• Lidocaine patches. These patches are applied to your skin and may offer pain relief. Shop for lidocaine patches here.

If your case of peripheral neuropathy is more serious, your doctor may recommend the following treatments:

• Transcutaneous electrical nerve stimulation. Electrodes are placed on the skin to deliver a gentle electric current to relieve symptoms.
• Physical therapy. Exercises can strengthen muscles and improve movements.
• Plasma exchange. A machine removes the plasma from your blood as well as antibodies that are attacking your immune system. The affected plasma is treated or replaced with a substitute and then returned to your body.

Multiple sclerosis

There’s no cure for MS yet, but treatment can manage symptoms in most cases. Treatment focuses on slowing MS progression and minimizing recovery time following flare-ups. Medications to treat MS include:

• alemtuzumab (Lemtrada)
• dimethyl fumarate (Tecfidera)
• fingolimod (Gilenya)
• glatiramer acetate (Copaxone)
• natalizumab (Tysabri)
• ocrelizumab (Ocrevus)
• teriflunomide (Aubagio)

Call 911 or your local emergency services if a burning sensation in your leg suddenly appears and is accompanied by:

• weakness or numbness on one side of your body
• headache
• a change in your level of consciousness

These can be signs that you’re experiencing a stroke. It’s vital to seek immediate medical attention for a good outcome and quicker recovery.

Burning in Knee: Causes and Treatments

Burning in Knee: Causes and Treatments

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Medically reviewed by William Morrison, M. D. — By Scott Frothingham — Updated on May 30, 2018

Burning knee pain

Because the knee one of the most actively used joints in the human body, pain in this joint isn’t an uncommon complaint. Although knee pain can take many forms, burning pain in the knee can be an indicator of a variety of problems.

You can have a burning sensation that seems to encompass the full knee, but often it’s felt in a specific area — most commonly behind the knee and in front of the knee (kneecap). For some, the burning sensation is focused along the sides of the knee.

There are several causes for burning in the knee. Where you feel the burning sensation has a lot to do with what’s causing the problem.

Burning behind the knee is often caused by:

• ligament tear
• cartilage tear
• overuse injury
• osteoarthritis

Burning in the front of the knee is often caused by an overuse injury known as runner’s knee – also referred to as chondromalacia or patellofemoral pain syndrome (PFS). As well, it could be tendonitis caused by the inflammation of the patellar tendon.

Burning on the outside of the knee is often caused by iliotibial band syndrome (ITBS).

Some people experience increased knee pain at night. This could be caused by a number of reasons:

• Blood vessels increase in diameter during sleep, putting pressure on nerves.
• Thinking about your physical pain without the distractions of the day results in an increase that’s psychologically driven.
• Hormone signals are reduced while you sleep, allowing more pain signals to get through to the brain.

Treatment for a burning knee depends on the cause.

Knee ligament tear

If a knee ligament tear is diagnosed as partial, treatment might include:

• muscle-strengthening exercises
• protective knee brace, to be used when exercising
• limits to activity that might cause further damage

A complete knee ligament tear might have to be surgically repaired.

Knee cartilage tear (damage to the joint surface)

The first stage of cartilage tear treatment is nonsurgical and could include:

• muscle-strengthening exercises like monitored physical therapy or a program of home exercise
• pain relief, typically nonsteroidal anti-inflammatory drugs (NSAIDs)
• steroid injections in the knee

For those whose situation doesn’t improve with more conservative treatment, the next stage is surgery. There are a number of surgical options including:

• Knee chondroplasty. The damaged cartilage is smoothed to reduce joint friction.
• Knee debridement. Loose pieces of cartilage are removed, and the joint is flushed with a saline solution (lavage).
• Osteochondral autograft transplantation (OATS). Undamaged cartilage is taken from a non-weight-bearing area and moved to the damaged area.
• Autologous chondrocyte implantation. A piece of cartilage is removed, cultivated in a lab, and put back into the knee, where it grows into healthy replacement cartilage.

Osteoarthritis in the knee

Osteoarthritis can’t be reversed, so the best that can be done is symptom management, which can include:

• pain management with over-the-counter (OTC) medication such as acetaminophen (Tylenol), ibuprofen (Advil, Motrin IB) and naproxen sodium (Aleve)
• physical and occupational therapy
• cortisone injections

Eventually, joint replacement surgery (arthroplasty) might be necessary.

Chondromalacia

Also known as runner’s knee, chondromalacia is the deterioration of the cartilage under the patella (kneecap). The initial treatment for chondromalacia includes:

• ice to reduce swelling following exercise
• pain relief with OTC medication
• rest for the knee joint, which includes avoiding squatting and kneeling
• alignment of the patella with a brace, tape, or a patellar-tracking sleeve

If the initial nonsurgical treatments fail, your doctor could suggest arthroscopic surgery to smooth unstable cartilage flaps and the trochlear groove (a groove on top of the femur).

Patellofemoral pain syndrome (PFS)

For mild cases, PFS is treated with:

• rest for the knee, which includes avoiding climbing stairs and kneeling
• OTC pain medications
• rehabilitation exercises, including those for quadriceps, hamstrings, and hip abductors
• supportive braces

For more severe cases, your doctor might recommend arthroscopy, a surgical procedure to remove fragments of damaged cartilage.

Patellar tendinitis

Patellar tendinitis is a common overuse injury to the tendon that connects your kneecap (patella) to your shinbone. It’s usually treated with:

• rest, especially avoiding running and jumping
• ice to reduce swelling
• pain management via OTC pain relievers
• exercise focused on the leg and thigh muscles
• stretching to lengthen the knee muscle-tendon unit
• patellar tendon strap to distribute force from the tendon to the strap

If conservative, noninvasive treatments aren’t effective, your doctor might recommend:

• platelet-rich plasma injection
• oscillating needle procedure

ITBS

ITBS is a repetitive knee strain injury experienced primarily by runners. Although at this time there is no definitive treatment for it, runners are usually advised to adhere to the following four-step program:

1. Stop running.
2. Cross-train with no-impact exercise like cycling and pool running.
3. Massage the quads, glutes, hamstrings, and iliotibial band.
4. Strengthen your core, the glutes, and the hip area.

Burning knee pain can indicate a problem with the joint or the soft tissues around the knee such as ligaments and tendons. If a burning pain in your knee seems to be associated with a specific area of the knee — front, back, or sides — you may be able to narrow down the potential causes of the pain.

If the pain persists or interferes with your daily activities or sleep, you should consult with your doctor.

Last medically reviewed on May 29, 2018

How we reviewed this article:

Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.

• Chondromalacia. (2013).
  health.harvard.edu/pain/chondromalacia-
• Knee ligament repair. (n.d.).
  hopkinsmedicine.org/healthlibrary/test_procedures/orthopaedic/knee_ligament_repair_92,P07675
• Mayo Clinic Staff. (2017). Patellofemoral pain syndrome.
  mayoclinic.org/diseases-conditions/patellofemoral-pain-syndrome/diagnosis-treatment/drc-20350797
• Mayo Clinic Staff. (2018). Osteoarthritis.
  mayoclinic.org/diseases-conditions/osteoarthritis/diagnosis-treatment/drc-20351930
• Mayo Clinic Staff. (2018). Patellar tendinitis.
  mayoclinic.org/diseases-conditions/patellar-tendinitis/diagnosis-treatment/drc-20376118
• Tiu T, et al. (2017). Knee overuse disorders.
  now.aapmr.org/knee-overuse-disorders/

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Medically reviewed by William Morrison, M. D. — By Scott Frothingham — Updated on May 30, 2018

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hot flashes during menopause, heat in the feet, general sensation of heat

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Heat is an influx of heat to any part of our body. We feel heat when the subcutaneous vessels expand, dramatically increasing blood flow to the surface of the skin. The autonomic nervous system is responsible for the activity of the vessels, so the feeling of heat can be a symptom of serious diseases.

Hot flashes during menopause

The resulting feeling of heat, covering the face, neck, chest, and accompanied by sweating, a feeling of lack of air, and often dizziness, is a common symptom in menopause. This rolling sensation of heat is called hot flashes. Hot flashes during menopause are associated with a violation of the general thermoregulation of the body caused by hormonal changes.

Unfortunately, it is rare that a woman does not experience hot flashes during menopause. However, the frequency of hot flashes can be reduced several times if you follow fairly simple rules: you should avoid overheating, do not wear excessively warm clothes, refrain from hot food and foods that increase the metabolic rate, and this is tea, pepper, coffee, energy-based caffeine.

Heat in the feet

Complaints of heat in the feet are quite common. They say that “the feet are on fire.” This may be a sign of a serious violation of microcirculation – blood supply in the small vessels of the legs, which is especially dangerous for people who are obese or have diabetes. In this case, you must definitely consult a doctor. An in-depth instrumental examination of the vessels of the legs may be required.

Another common cause of burning in the feet is a fungal infection of the skin. To exclude this option, it is necessary to pass tests for the fungal flora.

General sensation of heat

A feeling of heat throughout the body may be the result of a systemic metabolic disorder caused by a hormonal disease. In this case, it is possible to suspect a disease of the thyroid gland, gonads or adrenal glands. If you are worried about feeling hot, you should definitely visit an endocrinologist. For an accurate diagnosis, a laboratory blood test is required.

Fever accompanied by chills is a sure sign of illness. As a rule, fever and chills indicate an infection in the body, but it is also possible that this is a symptom of a more serious autoimmune disease (rheumatism, systemic lupus erythematosus). In case of fever, accompanied by chills, it is necessary to immediately consult a general practitioner, as well as conduct an examination to determine the exact cause.

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The reason for burning legs – articles Lab4u.RU

• February 13, 2023
• Author: Anna Fedortsova

Painfully burning legs, as a symptom, may be accompanied by numbness and paresthesia – a tingling sensation. Burning pain may be intermittent or constant. Vary from mild to severe. It partly intensifies at night.

Fatigue, walking, running, sitting in one position for a long time, or a skin infection can cause temporary burning or inflammation of the feet.

Most often, burning legs are a sign of peripheral neuropathy – nerve damage. They become hyperactive and send pain signals to the brain even if there is no wound or damage.

Treatment for burning feet will depend on the underlying cause:

Hypothyroidism

This is an underactive thyroid gland. It changes the balance of hormones in the body. Because of this, fluid accumulates in the tissues, especially in the limbs, and presses on the nerves. Other symptoms may include fatigue, constipation, dry skin, cold sensitivity, forgetfulness, and decreased libido.

Diabetes mellitus

Excess blood sugar damages the nerves in the arms and legs and causes a constant or intermittent burning sensation. Also, high glucose damages the capillaries that feed the nerves. Blood flow to the extremities is impaired, which reduces sensitivity and increases the risk of infections. Other symptoms of diabetes include constant thirst, frequent urination, dry mouth and lips, belching, cramps, vomiting, constipation, blurred vision.

Vitamin B deficiencies and vitamin deficiency anemia

They are needed for the formation of cells, the transport of oxygen to every cell of the body, the rapid transmission of nerve signals. With their deficiency, the transmission of nerve signals to the brain is disrupted. This results in numbness and tingling.
Vitamin B9 and B12 deficiencies can lead to anemia, a low level of red blood cells. Without them, oxygen does not reach the cells and they die, including nerve cells.
Weakness, fatigue, shortness of breath and palpitations, pallor or slight jaundice, an inflamed or “varnished” tongue, and an intoxicated gait are other symptoms of B vitamin deficiency.

Kidney diseases

Up to 10% of people with kidney disease experience swelling and tenderness in the lower legs with burning pain in the feet. Firstly, the removal of fluid from the body is disturbed and it puts pressure on the nerves. Secondly, the kidneys work as filters and help waste products leave our body. With various kidney diseases, they can accumulate and damage the nerves. In addition to burning feet and swelling, symptoms of kidney disease can include fatigue, blood in the urine, shortness of breath, itchy skin, and frequent urination.