About all

How long does linzess take to work. Linzess: How Long It Takes to Work and Proper Usage for Constipation Treatment

How long does Linzess take to work for constipation relief. What are the proper directions for taking Linzess. How should Linzess be stored and administered. What are the important considerations before starting Linzess treatment.

Содержание

Understanding Linzess: A Prescription Medication for IBS-C and CIC

Linzess (linaclotide) is a prescription medication designed to treat two specific gastrointestinal conditions in adults: irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation (CIC). The term “idiopathic” in CIC indicates that the cause of constipation is unknown. It’s crucial to note that Linzess is not approved for use in children under 18 years of age due to safety concerns.

What is Linzess used for?

Linzess is specifically indicated for:

  • Adults with irritable bowel syndrome with constipation (IBS-C)
  • Adults with chronic idiopathic constipation (CIC)

Important Safety Information

Before considering Linzess as a treatment option, it’s essential to be aware of its safety profile:

  • Linzess should not be given to children under 2 years of age due to potential harm
  • The medication can cause severe diarrhea, which may lead to dehydration
  • Its safety and efficacy in individuals under 18 years old have not been established

The Importance of Taking Linzess as Directed

Once prescribed Linzess, adherence to the treatment regimen is crucial for optimal results. Discontinuing the medication may lead to a recurrence of symptoms within approximately a week. Therefore, it’s imperative to follow your doctor’s recommendations and maintain open communication about your experience with Linzess.

How should Linzess be taken?

To maximize the effectiveness of Linzess, follow these guidelines:

  1. Take Linzess every day, unlike over-the-counter laxatives that are often used as needed
  2. Administer the medication once daily
  3. Take Linzess on an empty stomach, at least 30 minutes before your first meal of the day
  4. If you have difficulty swallowing capsules, you can open the Linzess capsule and sprinkle the beads onto applesauce or mix them with 1 oz (30mL) of water

Can you take two doses of Linzess if you miss one?

No, if you miss a dose of Linzess, do not take a double dose to make up for it. Instead, take your next dose as usual the following day. Consistency in taking the medication is key to its effectiveness.

Timeline for Linzess Effectiveness

Understanding when to expect results from Linzess can help manage expectations and ensure patients stick to their treatment plan.

How long does it take for Linzess to work?

When Linzess is taken daily as prescribed:

  • Constipation relief is typically experienced in about 1 week
  • IBS-C patients may begin to feel relief from belly pain and overall abdominal symptoms (including pain, discomfort, and bloating) in approximately 1 week
  • Symptoms typically continue to improve over a 12-week period

It’s important to note that abdominal symptoms were studied in combination, not individually.

Essential Information Before Starting Linzess Treatment

Before initiating Linzess treatment, patients should be well-informed about what to expect. Dr. Darren Brenner from Northwestern University Feinberg School of Medicine highlights four key points about taking Linzess:

What are the key points to know before starting Linzess?

  1. Proper administration of Linzess
  2. Expected timeline for symptom relief
  3. Common side effects
  4. Importance of consistent daily use

These points can help patients get off to the right start with their Linzess treatment.

Support and Resources for Linzess Patients

To enhance the treatment experience and promote adherence, various support programs and resources are available for Linzess patients.

What is the From the Gut℠ patient support program?

The From the Gut℠ program offers:

  • Wellness tips
  • Helpful tools
  • Daily medication reminders
  • A digital cookbook featuring gut-friendly recipes upon enrollment

This program can be beneficial for both new and existing Linzess users.

How can patients receive daily reminders for taking Linzess?

Patients can sign up for daily SMS text reminders by texting “ENROLL” to 70128. After answering a few quick questions, they will receive reminders at their preferred time.

Proactive Measures for Successful Linzess Treatment

Taking a proactive approach to Linzess treatment can significantly improve outcomes and patient satisfaction.

Why is it important to keep your doctor updated about Linzess treatment?

Regular communication with your healthcare provider is crucial because:

  • It allows your doctor to assess how Linzess is managing your IBS-C or CIC symptoms
  • You can report any side effects you may be experiencing
  • Your doctor can make necessary adjustments to your treatment plan if needed

How can patients ensure they don’t run out of Linzess?

To maintain consistent treatment:

  • Ask your pharmacist about refill reminder services
  • Notify your doctor or pharmacist if you need a refill before you run out
  • Inquire about pharmacy delivery services if you have difficulty getting to the pharmacy

Proper Storage and Handling of Linzess

Correct storage of Linzess is essential to maintain its effectiveness and safety.

What are the proper storage conditions for Linzess?

To ensure the medication remains effective:

  • Store Linzess at room temperature (68°F-77°F)
  • Keep the medication in its original bottle
  • Ensure the bottle is tightly closed and stored in a dry place
  • Do not remove the desiccant (drying agent) from the bottle
  • Keep Linzess out of reach of children

Always refer to the Medication Guide for complete storage instructions.

Financial Assistance and Additional Resources

For patients concerned about the cost of Linzess, there are programs available to help manage expenses.

What financial assistance is available for Linzess patients?

The Linzess Savings Program is designed to help eligible patients reduce their out-of-pocket costs for the medication. Patients should check the official Linzess website or consult with their healthcare provider for more information on eligibility and enrollment in this program.

Where can patients find additional resources about Linzess?

Patients can access additional information and resources through:

  • The official Linzess website
  • The From the Gut℠ program
  • Their healthcare provider
  • Patient support materials provided by the manufacturer

These resources can offer valuable insights into managing IBS-C and CIC with Linzess.

Understanding the proper use, expected timeline for effectiveness, and important considerations for Linzess treatment is crucial for patients dealing with IBS-C or CIC. By following the prescribed regimen, maintaining open communication with healthcare providers, and utilizing available support resources, patients can optimize their treatment experience and potentially improve their quality of life. Remember that while Linzess can be an effective treatment option, it’s important to discuss any concerns or side effects with a healthcare professional to ensure safe and appropriate use.

Constipation Treatment Directions | LINZESS (linaclotide)

CHECK MY SYMPTOMS

TALK TO A DOCTOR ONLINE

CHECK MY SYMPTOMS

WHY TAKING LINZESS AS DIRECTED MATTERS

Once you’ve been prescribed LINZESS, it’s important to stay on top of your treatment: If you stop taking your medication, your symptoms could return in about a week. Take the medication as recommended by your doctor and keep them informed about your experience with LINZESS.

TAKE LINZESS…

… EVERY DAY For LINZESS to work best, take it every day. This is different from over-the-counter laxatives, which are often taken as needed.

When LINZESS is taken daily, constipation relief is typically felt in about 1 week. IBS-C patients may begin to experience relief of belly pain and overall abdominal symptoms* (pain, discomfort, and bloating) in about 1 week, with symptoms typically improving over 12 weeks.

*Abdominal symptoms were studied in combination, not individually.

… ONCE A DAY If you miss a dose, take your dose as usual the following day. Do not take 2 doses at the same time to make up for a missed dose.

… ON AN EMPTY STOMACH Take your pill, as prescribed by your doctor, at least 30 minutes before your first meal of the day.

… WITH APPLESAUCE OR WATER, IF NECESSARY If you have trouble swallowing capsules, carefully open the LINZESS capsule and sprinkle all of the LINZESS beads onto applesauce or into 1 oz. (30mL) of water.

WHAT TO KNOW BEFORE STARTING LINZESS

Want to get off to the right start with LINZESS? Watch this short video where Dr. Darren Brenner shares 4 key points about how to take LINZESS and what to expect in terms of symptom relief and common side effects.

Transcript

“The purpose of this short video is to provide you with some important clinical information that may assist you in achieving a successful outcome when taking LINZESS.

Dr. Darren Brenner,
Northwestern University
Feinberg School of Medicine

View Transcript

GET TREATMENT TIPS, DAILY MEDICATION REMINDERS & MORE

Whether you already take LINZESS or are just starting treatment, get wellness tips, helpful tools, and more by enrolling in our From the Gut patient support program.

SIGN UP FOR SUPPORT

You’ll receive a From the Gut digital cookbook featuring gut-friendly recipes after joining!

SIGN UP

GET DAILY REMINDERS

Text “ENROLL” to 70128* to sign up for your LINZESS reminder. After answering a few quick questions, you’ll receive daily SMS text reminders at the time of your choosing.

TEXT ENROLL TO 70128*

BE PROACTIVE WITH YOUR TREATMENT

UPDATE YOUR DOCTOR

It’s important to keep your doctor informed about how LINZESS is working for you. Let them know how it may be helping to manage your IBS-C or CIC symptoms and if you’re experiencing any side effects.

REFILL ON TIME

Your local pharmacy may offer refill reminders—ask your pharmacist about signing up. Can’t make it to the pharmacy for a while? Notify your doctor or pharmacist to ensure you have enough medication. You may also want to check if your pharmacy offers delivery services.

HOW TO STORE LINZESS

Remember to store LINZESS at room temperature (68°F-77°F). It’s important to keep LINZESS in the bottle it comes in. Keep the LINZESS bottle tightly closed, in a dry place, and leave the desiccant (the drying agent that looks like a small cloth packet) in the bottle. Keep LINZESS out of the reach of children.

 

Please see Medication Guide for full instructions.

*By texting ENROLL to 70128, you consent to receive automated and recurring text messages from From the Gut regarding the From the Gut program, including enrollment instructions, patient support communications and medication reminders, to the mobile number that you used to enroll. You are not required to consent or provide your consent as a condition of receiving any goods or services from From the Gut. Message and data rates may apply. You also agree to the additional Terms and Conditions. Click AbbVie Privacy Policy for additional information about AbbVie’s privacy practices or click Ironwood Privacy Policy for more information about Ironwood Pharmaceuticals’ privacy practices.

FROM THE GUTSM TIPS & RESOURCES

LINZESS SAVINGS PROGRAM

USES

LINZESS® (linaclotide) is a prescription medication used in adults to treat irritable bowel syndrome with constipation (IBS‑C) and chronic idiopathic constipation (CIC). “Idiopathic” means the cause of the constipation is unknown. It is not known if LINZESS is safe and effective in children less than 18 years of age.

IMPORTANT RISK INFORMATION

  • Do not give LINZESS to children who are less than 2 years of age. It may harm them. LINZESS can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).
  • Do not take LINZESS if a doctor has told you that you have a bowel blockage (intestinal obstruction).

Before you take LINZESS, tell your doctor about your medical conditions, including if you are:

  • Pregnant or plan to become pregnant. It is not known if LINZESS will harm your unborn baby.
  • Breastfeeding or plan to breastfeed. You and your doctor should decide if you will take LINZESS and breastfeed.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.


Side Effects

LINZESS can cause serious side effects, including diarrhea, which is the most common side effect and can sometimes be severe. Diarrhea often begins within the first 2 weeks of LINZESS treatment. Stop taking LINZESS and call your doctor right away if you get severe diarrhea during treatment with LINZESS.

Other common side effects of LINZESS include gas, stomach-area (abdominal) pain, swelling, or a feeling of fullness or pressure in your abdomen (distension).  Call your doctor or go to the nearest hospital emergency room right away if you develop unusual or severe stomach-area (abdominal) pain, especially if you also have bright red, bloody stools or black stools that look like tar.

These are not all the possible side effects of LINZESS. For more information, ask your doctor or pharmacist.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

If you are having difficulty paying for your medicine, AbbVie and Ironwood may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.

US-LIN-220018

This information provided on this website is intended for U.S. healthcare professionals only.

I certify that I am a U.S. Healthcare Professional.

For adults with Irritable Bowel Syndrome with Constipation (IBS-C) or Chronic Idiopathic Constipation (CIC)

Answer a few quick questions about your symptoms.

Connect with a doctor online to find out if it could be IBS-C or CIC.

If approved, pick up your prescription from your local pharmacy.

*Third-party website; does not constitute an endorsement or recommendation by AbbVie. A fee will be charged by the telemedicine provider.

Acknowledge and Continue

Cancel

You are now leaving LINZESS.com

By clicking “Acknowledge and Continue” above, you acknowledge and agree that neither AbbVie nor Ironwood does, in any way, endorse or recommend UpScript, a telemedicine provider, the qualifications of any physician associated with UpScript, or the quality of medical care any of those physicians can provide. You also acknowledge and agree that neither AbbVie nor Ironwood makes any guarantees that using UpScript will result in your desired outcome. It is wholly and solely your responsibility to assess the qualifications of a potential physician. AbbVie and Ironwood recommend that you meet and discuss the benefits and risks of all potential treatments with the potential physician. ABBVIE, IRONWOOD, AND THEIR RESPECTIVE AFFILIATES HEREBY DISCLAIM ANY LIABILITY ARISING FROM YOUR USE AND/OR RELIANCE ON THE INFORMATION CONTAINED ON THE UPSCRIPT WEBSITE. If you agree to the above, click “Acknowledge and Continue” to proceed to the UpScript website. If you do not agree to the above, click “Cancel” to remain on LINZESS.com.

Did you know you can talk to a doctor today from the comfort of your home? Connect with a healthcare professional online about your symptoms.

NO THANKS

GET STARTED

Links to other websites are provided as a service to you. AbbVie and Ironwood Pharmaceuticals accept no responsibility for the content of other websites.

Would you like to continue?

Links to third-party content are provided as a convenience for informational purposes only. They are not meant to replace your healthcare provider’s medical advice or treatment. The organizations listed have not endorsed AbbVie and Ironwood or any of their respective products or services. AbbVie and Ironwood have listed these sites only as a convenience and according to the permissions granted by their respective terms of use. Each organization has its own terms and conditions and privacy policy that you should read if you choose to contact any of them.

Would you like to continue?

Transcript

USES

LINZESS® (linaclotide) is a prescription medication used in adults to treat irritable bowel syndrome with constipation (IBS‑C) and chronic idiopathic constipation (CIC). “Idiopathic” means the cause of the constipation is unknown. It is not known if LINZESS is safe and effective in children less than 18 years of age.

IMPORTANT RISK INFORMATION

  • Do not give LINZESS to children who are less than 2 years of age. It may harm them. LINZESS can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).
  • Do not take LINZESS if a doctor has told you that you have a bowel blockage (intestinal obstruction).

Before you take LINZESS, tell your doctor about your medical conditions, including if you are:

USES

LINZESS® (linaclotide) is a prescription medication used in adults to treat irritable bowel syndrome with constipation (IBS‑C) and chronic idiopathic constipation (CIC). “Idiopathic” means the cause of the constipation is unknown. It is not known if LINZESS is safe and effective in children less than 18 years of age.

IMPORTANT RISK INFORMATION

  • Do not give LINZESS to children who are less than 2 years of age. It may harm them. LINZESS can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).

USES

LINZESS® (linaclotide) is a prescription medication used in adults to treat irritable bowel syndrome with constipation (IBS‑C) and chronic idiopathic constipation (CIC). “Idiopathic” means the cause of the constipation is unknown.  It is not known if LINZESS is safe and effective in children less than 18 years of age.

IMPORTANT RISK INFORMATION

  • Do not give LINZESS to children who are less than 2 years of age. It may harm them. LINZESS can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).
  • Do not take LINZESS if a doctor has told you that you have a bowel blockage (intestinal obstruction).

Before you take LINZESS, tell your doctor about your medical conditions, including if you are:

USES

LINZESS® (linaclotide) is a prescription medication used in adults to treat irritable bowel syndrome with constipation (IBS‑C) and chronic idiopathic constipation (CIC). “Idiopathic” means the cause of the constipation is unknown. It is not known if LINZESS is safe and effective in children less than 18 years of age.

IMPORTANT RISK INFORMATION

  • Do not give LINZESS to children who are less than 2 years of age. It may harm them. LINZESS can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).

USES

LINZESS® (linaclotide) is a prescription medication used in adults to treat irritable bowel syndrome with constipation (IBS‑C) and chronic idiopathic constipation (CIC). “Idiopathic” means the cause of the constipation is unknown. It is not known if LINZESS is safe and effective in children less than 18 years of age.

IMPORTANT RISK INFORMATION

  • Do not give LINZESS to children who are less than 2 years of age. It may harm them. LINZESS can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).
  • Do not take LINZESS if a doctor has told you that you have a bowel blockage (intestinal obstruction).

Before you take LINZESS, tell your doctor about your medical conditions, including if you are:

  • Pregnant or plan to become pregnant. It is not known if LINZESS will harm your unborn baby.
  • Breastfeeding or plan to breastfeed. You and your doctor should decide if you will take LINZESS and breastfeed.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.


Side Effects

LINZESS can cause serious side effects, including diarrhea, which is the most common side effect and can sometimes be severe. Diarrhea often begins within the first 2 weeks of LINZESS treatment. Stop taking LINZESS and call your doctor right away if you get severe diarrhea during treatment with LINZESS.

Other common side effects of LINZESS include gas, stomach-area (abdominal) pain, swelling, or a feeling of fullness or pressure in your abdomen (distension). Call your doctor or go to the nearest hospital emergency room right away if you develop unusual or severe stomach-area (abdominal) pain, especially if you also have bright red, bloody stools or black stools that look like tar.

These are not all the possible side effects of LINZESS. For more information, ask your doctor or pharmacist.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

If you are having difficulty paying for your medicine, AbbVie and Ironwood may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.

US-LIN-220018

Frequently Asked Questions | LINZESS (linaclotide)

CHECK MY SYMPTOMS

TALK TO A DOCTOR ONLINE

CHECK MY SYMPTOMS

FREQUENTLY ASKED QUESTIONS ABOUT IBS-C, CIC & LINZESS

IBS-C, CIC & CHRONIC CONSTIPATION

WHAT LINZESS DOES & HOW IT CAN HELP

GETTING TREATMENT & MORE RESOURCES

YOUR LINZESS PRESCRIPTION

CHECK MY SYMPTOMS

HOW LINZESS CAN HELP

TYPES OF CONSTIPATION

USES

LINZESS® (linaclotide) is a prescription medication used in adults to treat irritable bowel syndrome with constipation (IBS‑C) and chronic idiopathic constipation (CIC). “Idiopathic” means the cause of the constipation is unknown. It is not known if LINZESS is safe and effective in children less than 18 years of age.

IMPORTANT RISK INFORMATION

  • Do not give LINZESS to children who are less than 2 years of age. It may harm them. LINZESS can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).
  • Do not take LINZESS if a doctor has told you that you have a bowel blockage (intestinal obstruction).

Before you take LINZESS, tell your doctor about your medical conditions, including if you are:

  • Pregnant or plan to become pregnant. It is not known if LINZESS will harm your unborn baby.
  • Breastfeeding or plan to breastfeed. You and your doctor should decide if you will take LINZESS and breastfeed.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.


Side Effects

LINZESS can cause serious side effects, including diarrhea, which is the most common side effect and can sometimes be severe. Diarrhea often begins within the first 2 weeks of LINZESS treatment. Stop taking LINZESS and call your doctor right away if you get severe diarrhea during treatment with LINZESS.

Other common side effects of LINZESS include gas, stomach-area (abdominal) pain, swelling, or a feeling of fullness or pressure in your abdomen (distension). Call your doctor or go to the nearest hospital emergency room right away if you develop unusual or severe stomach-area (abdominal) pain, especially if you also have bright red, bloody stools or black stools that look like tar.

These are not all the possible side effects of LINZESS. For more information, ask your doctor or pharmacist.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

If you are having difficulty paying for your medicine, AbbVie and Ironwood may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.

US-LIN-220018

Links to third-party content are provided as a convenience for informational purposes only. They are not meant to replace your healthcare provider’s medical advice or treatment. The organizations listed have not endorsed AbbVie and Ironwood or any of their respective products or services. AbbVie and Ironwood have listed these sites only as a convenience and according to the permissions granted by their respective terms of use. Each organization has its own terms and conditions and privacy policy that you should read if you choose to contact any of them.

Would you like to continue?

Links to third-party content are provided as a convenience for informational purposes only. They are not meant to replace your healthcare provider’s medical advice or treatment. The organizations listed have not endorsed AbbVie and Ironwood or any of their respective products or services. AbbVie and Ironwood have listed these sites only as a convenience and according to the permissions granted by their respective terms of use. Each organization has its own terms and conditions and privacy policy that you should read if you choose to contact any of them.

Would you like to continue?

Links to third-party content are provided as a convenience for informational purposes only. They are not meant to replace your healthcare provider’s medical advice or treatment. The organizations listed have not endorsed AbbVie and Ironwood or any of their respective products or services. AbbVie and Ironwood have listed these sites only as a convenience and according to the permissions granted by their respective terms of use. Each organization has its own terms and conditions and privacy policy that you should read if you choose to contact any of them.

Would you like to continue?

Links to third-party content are provided as a convenience for informational purposes only. They are not meant to replace your healthcare provider’s medical advice or treatment. The organizations listed have not endorsed AbbVie and Ironwood or any of their respective products or services. AbbVie and Ironwood have listed these sites only as a convenience and according to the permissions granted by their respective terms of use. Each organization has its own terms and conditions and privacy policy that you should read if you choose to contact any of them. br>
Would you like to continue?

 

Links to third-party content are provided as a convenience for informational purposes only. They are not meant to replace your healthcare provider’s medical advice or treatment. The organizations listed have not endorsed AbbVie and Ironwood or any of their respective products or services. AbbVie and Ironwood have listed these sites only as a convenience and according to the permissions granted by their respective terms of use. Each organization has its own terms and conditions and privacy policy that you should read if you choose to contact any of them.

Would you like to continue?

Links to third-party content are provided as a convenience for informational purposes only. They are not meant to replace your healthcare provider’s medical advice or treatment. The organizations listed have not endorsed AbbVie and Ironwood or any of their respective products or services. AbbVie and Ironwood have listed these sites only as a convenience and according to the permissions granted by their respective terms of use. Each organization has its own terms and conditions and privacy policy that you should read if you choose to contact any of them.

Would you like to continue?

Links to third-party content are provided as a convenience for informational purposes only. They are not meant to replace your healthcare provider’s medical advice or treatment. The organizations listed have not endorsed AbbVie and Ironwood or any of their respective products or services. AbbVie and Ironwood have listed these sites only as a convenience and according to the permissions granted by their respective terms of use. Each organization has its own terms and conditions and privacy policy that you should read if you choose to contact any of them.

Would you like to continue?

Links to third-party content are provided as a convenience for informational purposes only. They are not meant to replace your healthcare provider’s medical advice or treatment. The organizations listed have not endorsed AbbVie and Ironwood or any of their respective products or services. AbbVie and Ironwood have listed these sites only as a convenience and according to the permissions granted by their respective terms of use. Each organization has its own terms and conditions and privacy policy that you should read if you choose to contact any of them.

Would you like to continue?

Links to third-party content are provided as a convenience for informational purposes only. They are not meant to replace your healthcare provider’s medical advice or treatment. The organizations listed have not endorsed AbbVie and Ironwood or any of their respective products or services. AbbVie and Ironwood have listed these sites only as a convenience and according to the permissions granted by their respective terms of use. Each organization has its own terms and conditions and privacy policy that you should read if you choose to contact any of them.

Would you like to continue?

This information provided on this website is intended for U.S. healthcare professionals only.

I certify that I am a U.S. Healthcare Professional.

For adults with Irritable Bowel Syndrome with Constipation (IBS-C) or Chronic Idiopathic Constipation (CIC)

Answer a few quick questions about your symptoms.

Connect with a doctor online to find out if it could be IBS-C or CIC.

If approved, pick up your prescription from your local pharmacy.

*Third-party website; does not constitute an endorsement or recommendation by AbbVie. A fee will be charged by the telemedicine provider.

Acknowledge and Continue

Cancel

You are now leaving LINZESS. com

By clicking “Acknowledge and Continue” above, you acknowledge and agree that neither AbbVie nor Ironwood does, in any way, endorse or recommend UpScript, a telemedicine provider, the qualifications of any physician associated with UpScript, or the quality of medical care any of those physicians can provide. You also acknowledge and agree that neither AbbVie nor Ironwood makes any guarantees that using UpScript will result in your desired outcome. It is wholly and solely your responsibility to assess the qualifications of a potential physician. AbbVie and Ironwood recommend that you meet and discuss the benefits and risks of all potential treatments with the potential physician. ABBVIE, IRONWOOD, AND THEIR RESPECTIVE AFFILIATES HEREBY DISCLAIM ANY LIABILITY ARISING FROM YOUR USE AND/OR RELIANCE ON THE INFORMATION CONTAINED ON THE UPSCRIPT WEBSITE. If you agree to the above, click “Acknowledge and Continue” to proceed to the UpScript website. If you do not agree to the above, click “Cancel” to remain on LINZESS. com.

Did you know you can talk to a doctor today from the comfort of your home? Connect with a healthcare professional online about your symptoms.

NO THANKS

GET STARTED

Links to other websites are provided as a service to you. AbbVie and Ironwood Pharmaceuticals accept no responsibility for the content of other websites.

Would you like to continue?

Links to third-party content are provided as a convenience for informational purposes only. They are not meant to replace your healthcare provider’s medical advice or treatment. The organizations listed have not endorsed AbbVie and Ironwood or any of their respective products or services. AbbVie and Ironwood have listed these sites only as a convenience and according to the permissions granted by their respective terms of use. Each organization has its own terms and conditions and privacy policy that you should read if you choose to contact any of them.

Would you like to continue?

Transcript

USES

LINZESS® (linaclotide) is a prescription medication used in adults to treat irritable bowel syndrome with constipation (IBS‑C) and chronic idiopathic constipation (CIC). “Idiopathic” means the cause of the constipation is unknown. It is not known if LINZESS is safe and effective in children less than 18 years of age.

IMPORTANT RISK INFORMATION

  • Do not give LINZESS to children who are less than 2 years of age. It may harm them. LINZESS can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).
  • Do not take LINZESS if a doctor has told you that you have a bowel blockage (intestinal obstruction).

Before you take LINZESS, tell your doctor about your medical conditions, including if you are:

USES

LINZESS® (linaclotide) is a prescription medication used in adults to treat irritable bowel syndrome with constipation (IBS‑C) and chronic idiopathic constipation (CIC). “Idiopathic” means the cause of the constipation is unknown. It is not known if LINZESS is safe and effective in children less than 18 years of age.

IMPORTANT RISK INFORMATION

  • Do not give LINZESS to children who are less than 2 years of age. It may harm them. LINZESS can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).

USES

LINZESS® (linaclotide) is a prescription medication used in adults to treat irritable bowel syndrome with constipation (IBS‑C) and chronic idiopathic constipation (CIC). “Idiopathic” means the cause of the constipation is unknown. It is not known if LINZESS is safe and effective in children less than 18 years of age.

IMPORTANT RISK INFORMATION

  • Do not give LINZESS to children who are less than 2 years of age. It may harm them. LINZESS can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).
  • Do not take LINZESS if a doctor has told you that you have a bowel blockage (intestinal obstruction).

Before you take LINZESS, tell your doctor about your medical conditions, including if you are:

USES

LINZESS® (linaclotide) is a prescription medication used in adults to treat irritable bowel syndrome with constipation (IBS‑C) and chronic idiopathic constipation (CIC). “Idiopathic” means the cause of the constipation is unknown. It is not known if LINZESS is safe and effective in children less than 18 years of age.

IMPORTANT RISK INFORMATION

  • Do not give LINZESS to children who are less than 2 years of age. It may harm them. LINZESS can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).

USES

LINZESS® (linaclotide) is a prescription medication used in adults to treat irritable bowel syndrome with constipation (IBS‑C) and chronic idiopathic constipation (CIC). “Idiopathic” means the cause of the constipation is unknown.  It is not known if LINZESS is safe and effective in children less than 18 years of age.

IMPORTANT RISK INFORMATION

  • Do not give LINZESS to children who are less than 2 years of age. It may harm them. LINZESS can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).
  • Do not take LINZESS if a doctor has told you that you have a bowel blockage (intestinal obstruction).

Before you take LINZESS, tell your doctor about your medical conditions, including if you are:

  • Pregnant or plan to become pregnant. It is not known if LINZESS will harm your unborn baby.
  • Breastfeeding or plan to breastfeed. You and your doctor should decide if you will take LINZESS and breastfeed.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.


Side Effects

LINZESS can cause serious side effects, including diarrhea, which is the most common side effect and can sometimes be severe.  Diarrhea often begins within the first 2 weeks of LINZESS treatment. Stop taking LINZESS and call your doctor right away if you get severe diarrhea during treatment with LINZESS.

Other common side effects of LINZESS include gas, stomach-area (abdominal) pain, swelling, or a feeling of fullness or pressure in your abdomen (distension). Call your doctor or go to the nearest hospital emergency room right away if you develop unusual or severe stomach-area (abdominal) pain, especially if you also have bright red, bloody stools or black stools that look like tar.

These are not all the possible side effects of LINZESS. For more information, ask your doctor or pharmacist.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

If you are having difficulty paying for your medicine, AbbVie and Ironwood may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.

US-LIN-220018

Linzess side effects and how to avoid them | SingleCare – Product Information

Home >> Product Information >> Linzess Side Effects and How to Avoid Them

Information about the drug

Side effects of Linzess | Serious side effects | How long do side effects last? | Warnings | Interactions | How to avoid side effects

Linzess is a brand name for a generic drug called linaclotide. It is a prescription drug used to treat chronic constipation and works by increasing the secretion in the intestines of two chemical compounds called chloride and bicarbonate. This causes more intestinal fluid to be secreted, which helps make stool easier to pass. Linzess also shortens the time it takes for food to pass through the digestive tract.

Linzess can treat two types of chronic constipation called irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation (CIC). In both cases, constipation persists for three months or longer. Let’s take a look at Linzess’ common side effects, warnings, and drug interactions to better understand the drug and how it works.

RELATED: What is Linzess?

Common side effects Linzess

Linzess can cause side effects like any other medicine, and for many people with IBS-C or CEC, the benefits outweigh any side effects they may experience. Here are the most common side effects of Linzess:

  • Abdominal pain
  • Diarrhea
  • Flatulence (gas)
  • Headaches
  • Gastroenteritis (inflammation of the intestines) 900 32
  • Bloating (bloating)

Because Linzess shortens the time it takes to pass through the gastrointestinal tract, diarrhea is the most common side effect. It is normal for one or more of these side effects to occur while taking Linzess, and while they may be uncomfortable, many people will begin to experience relief from chronic constipation shortly after starting Linzess.

Serious side effects Linzess

Rarely, Linzess may cause more serious side effects that may require medical attention:

Severe diarrhea

If you are taking Linzess and have diarrhea that gets worse or does not go away, especially if you have bloody or black stools, then you should stop taking Linzess and see your doctor to see if continuing is right for you taking medication. Your doctor can advise what to do. In rare cases, severe diarrhea can lead to dizziness or fainting, and hospitalization may be required to replace the loss of electrolytes due to dehydration.

Anaphylaxis

Anaphylaxis is a severe allergic reaction to a drug, food, or poison. It’s very rare for someone to have an allergic reaction to Linzess, but it’s possible, and anaphylaxis can be life-threatening if not treated right away. If you begin to experience difficulty breathing, swelling of the throat, nausea, vomiting, shock, and/or hives after taking Linzess, you should seek immediate medical attention.

Weight Loss

Some people who take Linzess for chronic constipation may lose weight. This may be because the medication can cause diarrhea and loss of water and electrolytes from the body, which can lead to weight loss if not treated right away. Diarrhea often begins within the first two weeks of taking Linzess, and in placebo-controlled studies, about twenty% of people with IBS-C experienced diarrhea compared to placebo groups who did not receive the medication. Some mild diarrhea is common, but if you experience severe diarrhea while taking Linzess, you should stop taking it and call your doctor right away. This is especially important for older people who are more prone to dehydration.

Depression

There is very little research to suggest that Linzess causes depression, but there may be an association between depression, anxiety and IBS-C. This is because the gut is partly controlled by the nervous system, which sends signals to the brain. It is estimated that about fifty% of people with IBS-C will also have symptoms of anxiety and depression. Someone who is taking Linzess for IBS-3 and feels anxious or depressed may feel it because of the anxiety or depression rather than the medication.

If you are taking Linzess and start feeling overwhelmed, it is best to talk to your doctor or health care professional about what might be making you feel the same way. Your doctor can help you figure out if Linzess is making you feel more anxious and depressed.

In addition, if you develop suicidal thoughts or behavior, you should seek immediate medical attention. You can also call the National Suicide Prevention Helpline free of charge at 1-800-273-8255 if you need someone to talk to. Lifeline is available 24 hours a day.

RELATED: Is IBS a concern?

Hair Loss

People with digestive disorders can have many causes of hair loss, such as stress, intestinal inflammation, or inadequate absorption of nutrients from food. Many medications are also known to cause hair loss, but there is not enough evidence that Linzess does this. Hair loss is not on the list of side effects of Linzess. It is certainly possible for someone to experience side effects from a medication that other people are not taking, and if this happens to you, you should tell your doctor about it. You can also report side effects to the Food and Drug Administration (FDA) at 1-800-FDA-1088.

RELATED: Why is my hair falling out?

How long do the side effects of Linzess last?

For the average person taking Linzess, the most common side effect is diarrhea, which usually occurs within the first two weeks of treatment. In clinical trials, diarrhea disappeared within a week in about 33% of people. Although many side effects will disappear in a short period of time, longer-term side effects are possible. Some people have diarrhea for up to a month, so it really depends on the person and how their body processes Linzess. If you’ve been taking lensess for more than two weeks and your side effects persist, it may be worth seeing your doctor to make sure what you’re experiencing is okay.

Note: Lenses is not a laxative and does not work immediately. Most people begin to experience relief from symptoms of chronic constipation about a week after starting treatment at Linzess, and patients with IBS-C usually see improvements in their health over the course of treatment. 12 weeks.

Linzess Contraindications and Warnings

Abuse and Dependence

Linzess belongs to a group of medicines called guanylate cyclase-C agonists, which work by increasing the secretion of intestinal fluid. There is no evidence that these drugs are addictive.

Linzess should only be taken with a doctor’s prescription. Taking lensess more than the recommended daily dose to make it work faster is unsafe and won’t work. Taking medicines that you have not been prescribed can be harmful to your health.

If someone with IBS-C or CIC needs to stop taking Linzess for any reason, they may experience some mild withdrawal symptoms such as changes in bowel movements. Many people will see symptoms of chronic constipation return within a week or by stopping Linzess.

Overdose

The maximum dose of Linzess per day is 290 micrograms, unless otherwise recommended by a physician. An overdose of Linzess is unlikely to be life-threatening, but may cause some symptoms, such as diarrhea.

Restrictions

Although Linzess is an effective treatment for IBS-C and CEC, it should not be taken by anyone with chronic constipation.

Linzess should not be used in pediatric patients under 18 years of age as its safety and efficacy in this age group have not been adequately established. Children under 6 years of age should not use Linzess at all as it can cause severe dehydration.

Linzess should also not be taken by people with known or suspected mechanical ileus (bowel obstruction).

Linzess should be avoided during pregnancy or breastfeeding unless approved by a physician. Linzess has not been well studied in pregnant women. There are no human data to suggest that Linzess will harm a fetus or could be harmful to babies if it passes into breast milk, but it should not be used unless the benefits outweigh the risks.

Elderly patients over 65 years of age should be closely monitored when taking Linzess. The effects of Linzess have not been specifically studied in this population. Dose adjustment is not required, but older patients may have higher rates of liver and kidney problems, requiring more caution when taking this medication.

Linzess Interactions

Laxatives such as sodium phosphate, magnesium citrate and polyethylene glycol should be avoided when starting Linzess as they may increase the chance of diarrhea. If you take certain medications while taking Linzess, you may increase your risk of dehydration, so it’s best to give your doctor a list of all medications (including prescription, over-the-counter medications, and supplements) you are taking so that he or she can tell you if there is anything what you shouldn’t take.

How to avoid the side effects of Linzess

Although it may not be possible to completely avoid the side effects of Linzess, there are a few things you can do to reduce their severity:

1. Take the recommended dose.

The recommended daily dose of Linzess for the treatment of IBS-C is 290 micrograms on an empty stomach, at least 30 minutes before the first meal of the day. The recommended daily dose of Linzess for CIC is 145 mcg taken at least 30 minutes before the first meal of the day. A dosage of 72 mcg taken once a day can also be used for patients with CEC who have poor tolerance to Linzess.

It is very important to be consistent in how and when you take your medications because consistency will help your body digest lensess better and reduce the chance of side effects. Taking the prescribed dose each morning 30 minutes before your first meal of the day will make a big difference in how well Linzess works for you.

If you miss a dose of Linzess, skip the missed dose and take your next dose the next day before your first meal. Refer to the Medication Guide for more information on medications.

Linzess must not be crushed or chewed. If you find it difficult to swallow the tablets, you can open the Linzess capsule and pour the medicine into 1 teaspoon of applesauce or 30 ml of water.

Store Linzess Properly

It is important to know how to properly store your medicines so that they remain as effective as possible. Taking expired or improperly stored medicines can cause the medicine to work incorrectly and even cause unwanted side effects. Linzess should be stored at room temperature in a dry place in the original container. It is also important to leave the drying agent, which is part of the vial, inside the vial so that excess moisture does not affect the medicine, and the vial should be tightly closed.

3. Share your medical history with your doctor.

Giving your doctor a complete medical history is important to help your doctor understand how well Linzess is a good fit for you. If you provide your doctor with a complete list of all medications and supplements you are taking, he can see if what you are already taking will interfere with your Linzess treatment and cause possible side effects. Your doctor will adjust your dose if necessary, or switch you to another medicine, such as Amitiza, if side effects persist.

4. Listen to your body

It is important to listen to your body when taking lenses. If you start experiencing any Linzess side effects, it’s best to let your doctor know as soon as possible so they can help you reduce the severity of these side effects. Many people will be able to take Linzess safely for a long time with minimal side effects if taken correctly, but others may respond differently to it.

According to the FDA, in a long-term study in which 2147 people with IBS-X received 290 mcg lensesse daily for up to 18 months, in 29% of patients the dose was reduced or stopped due to the occurrence of adverse reactions such as diarrhea. These possible side effects should be closely monitored by listening to how your body feels while you are taking Linzess and by keeping in close contact with your doctor.

5 options for treating chronic constipation that must be on prescription

content:
  • What are the prescription drug options?
  • 1. Linaclotide (Linzess)
  • 2. Lubiprostone (Amitiza)
  • 3. Plecanatide (Trulance)
  • 4. Misoprostol (Cytotec)
  • 5. Lactulose (crystalose, cefulac)

When you’re constipated, it definitely doesn’t work because you have difficulty defecation. This condition can usually be resolved immediately by taking free medicines purchased from a pharmacy. In cases of chronic constipation, a doctor may prescribe constipation medicine to help with bowel movements.

Unlike over-the-counter drugs at pharmacies, you can get the following prescription drugs for constipation during a doctor’s examination that indicates that your constipation is already moderate.

1. Linaclotide (Linzess)

Linaclotide is a capsule form to be taken once daily on an empty stomach, at least 30 minutes before meals. This drug works by stimulating the cells lining the intestines to expel fluid to increase bowel movements.

In addition to treating constipation, linaclotide also helps to overcome irritable bowel syndrome (IBS). It is not recommended to drink to children under the age of 17 years.

2. Lubiprostone (Amitiza)

Lubiprostone is a prescription constipation medicine commonly prescribed to treat chronic constipation, constipation associated with IBS, or constipation caused by opioid pain relievers. Rules to drink lubisprostone twice a day with food and water as recommended by your doctor.

This drug works by increasing bowel movements, reducing intestinal tension, and adding fluid to the stool to make the texture easier to remove from the body. Side effects that may appear are nausea, vomiting, headaches and diarrhea.

3. Plecanatide (Trulance)

Plakanatide is an oral medication that is taken once a day. The goal is to help the body produce more fluid in the intestines so that the stool becomes soft and easy to pass out of the body.

This constipation prescription is more specifically for people who experience chronic idiopathic constipation (constipation that is unknown and of long duration). However, doctors may prescribe the drug plecanatide if other types of medication fail to treat constipation. Plecanatide may cause side effects such as diarrhea.

4. Misoprostol (Cytotec)

Misoprostol is actually meant to prevent stomach ulcers from NSAIDs (aspirin, ibuprofen, naproxen). But a number of studies show that this drug can help relieve constipation, reports Web MD.

Because misoprostol can speed up bowel movements and cause stools. However, this drug is believed to be effective only in the short term. Pregnant women should avoid taking misoprostol.