How much Benadryl is safe to take. What is the correct dosage for adults and children. What are the risks of taking too much Benadryl. How does Benadryl work to relieve allergy symptoms.

Understanding Benadryl and Its Active Ingredient

Benadryl is a widely used over-the-counter medication containing the active ingredient diphenhydramine. This antihistamine is employed to alleviate various symptoms, including those associated with allergic rhinitis, common cold, and skin irritations. Its versatility extends to treating conditions like motion sickness and insomnia.

Diphenhydramine works by blocking the effects of histamine, a substance produced by the body during allergic reactions. This action helps reduce symptoms such as sneezing, runny nose, itchy eyes, and skin irritations.

Available Forms of Benadryl

• Oral forms: tablets, chewable tablets, liquid-filled capsules, liqui-gels, and liquid solutions
• Topical forms: creams, gels, and sprays

Some combination products contain diphenhydramine along with other active ingredients. For instance, Benadryl Allergy Plus Congestion for Sinus Pressure & Nasal Congestion Relief combines diphenhydramine with phenylephrine, a nasal decongestant.

Proper Benadryl Dosage for Adults

The appropriate Benadryl dosage for adults depends on the condition being treated and the form of the medication. Generally, for hay fever, allergies, and common cold symptoms, the recommended dose is 25 mg to 50 mg every 4 to 6 hours.

Can adults take more than 50 mg of Benadryl? It’s not recommended to exceed 50 mg per dose or 300 mg per day unless directed by a healthcare provider. Taking more than the recommended dose can increase the risk of side effects and potential overdose.

Factors Affecting Adult Dosage

• Age and overall health
• Severity of symptoms
• Other medications being taken
• Individual sensitivity to diphenhydramine

Always consult with a healthcare professional before adjusting your Benadryl dosage, especially if you have any underlying health conditions or are taking other medications.

Benadryl Dosage for Children

Determining the correct Benadryl dosage for children requires careful consideration of age, weight, and the specific formulation being used. It’s crucial to follow the dosing instructions provided by a healthcare professional or on the product label.

Age-Based Dosage Guidelines

• Children 12 years and older: 25 mg to 50 mg every 4 to 6 hours
• Children 6-12 years: 12.5 mg to 25 mg every 4 to 6 hours
• Children under 6 years: Should not take oral Benadryl without a doctor’s prescription

Is it safe to give Benadryl to infants? Benadryl is not recommended for infants or children under 2 years old without explicit medical advice. For children between 2 and 6 years, consult a pediatrician before administering any antihistamine.

Weight-Based Dosing Chart

When administering Benadryl to children, always use the measuring device provided with the medication for accurate dosing. Avoid using household spoons, as they can lead to dosing errors.

Benadryl for Topical Use

Topical Benadryl products, such as creams, gels, and sprays, are used to relieve itchy skin from insect bites, stings, hives, and other allergic reactions. These formulations can be used by adults and children 2 years and older, unless otherwise directed by a healthcare provider.

Applying Topical Benadryl Safely

• Clean the affected area before application
• Apply a thin layer to the skin, avoiding broken or irritated areas
• Use up to 3 to 4 times daily, or as directed
• Wash hands after application unless treating the hands

How often can you apply topical Benadryl? Most topical Benadryl products can be applied up to 3 to 4 times daily. However, always follow the specific instructions on the product label or as advised by your healthcare provider.

Risks of Exceeding Recommended Benadryl Dosage

Taking more Benadryl than recommended can lead to various adverse effects and potential health risks. It’s crucial to adhere to the prescribed dosage and consult a healthcare professional if symptoms persist or worsen.

Potential Side Effects of Overdose

• Severe drowsiness and dizziness
• Dry mouth, nose, and throat
• Blurred vision
• Rapid heartbeat
• Difficulty urinating
• Confusion and hallucinations
• Seizures (in severe cases)

What happens if you take too much Benadryl? Taking excessive amounts of Benadryl can lead to a condition known as anticholinergic toxicity, which can be life-threatening. Symptoms may include severe confusion, hallucinations, seizures, and potentially coma. If you suspect an overdose, seek immediate medical attention.

Special Considerations and Precautions

While Benadryl is generally safe when used as directed, certain individuals should exercise caution or avoid its use altogether. Understanding these special considerations is crucial for safe and effective use of the medication.

Groups at Higher Risk

• Elderly individuals
• People with certain medical conditions (e.g., glaucoma, enlarged prostate)
• Pregnant or breastfeeding women
• Those taking other medications that may interact with diphenhydramine

Can Benadryl interact with other medications? Yes, Benadryl can interact with various medications, including other antihistamines, antidepressants, and some antipsychotic drugs. Always inform your healthcare provider about all medications you’re taking, including over-the-counter drugs and supplements.

Alcohol and Benadryl

Combining Benadryl with alcohol can intensify its sedative effects, leading to increased drowsiness and impaired coordination. It’s advisable to avoid alcohol consumption when taking Benadryl or other antihistamines.

Alternatives to Benadryl

While Benadryl is effective for many people, some individuals may seek alternatives due to side effects or personal preferences. Several other antihistamines and allergy relief options are available, both over-the-counter and by prescription.

Other Antihistamine Options

• Cetirizine (Zyrtec)
• Loratadine (Claritin)
• Fexofenadine (Allegra)
• Desloratadine (Clarinex)

These second-generation antihistamines often cause less drowsiness compared to Benadryl and may be suitable for daytime use.

Natural Remedies for Allergy Relief

Some individuals prefer natural approaches to managing allergy symptoms. While these methods may not be as potent as antihistamines, they can provide some relief:

• Nasal irrigation with saline solution
• Using a HEPA air purifier
• Consuming local honey (for seasonal allergies)
• Incorporating certain herbs like butterbur or stinging nettle

Are natural remedies as effective as Benadryl? While some natural remedies may offer relief for mild allergy symptoms, they generally are not as potent or fast-acting as antihistamines like Benadryl. Consult with a healthcare provider before relying solely on natural remedies, especially for severe allergies.

When to Seek Medical Advice

While Benadryl is generally safe when used as directed, there are situations where medical attention may be necessary. Recognizing these scenarios is crucial for maintaining your health and safety.

Signs That Warrant Medical Attention

• Allergic symptoms that worsen or don’t improve with Benadryl use
• Experiencing severe side effects such as rapid heartbeat or difficulty breathing
• Signs of an overdose, including confusion, hallucinations, or seizures
• Persistent symptoms that require long-term use of Benadryl

When should you consult a doctor about your Benadryl use? If you find yourself needing to take Benadryl regularly for more than a few weeks, it’s advisable to consult a healthcare provider. They can assess your symptoms, provide a proper diagnosis, and recommend more appropriate long-term treatment options if necessary.

Allergic Emergencies

It’s important to note that Benadryl is not a substitute for emergency treatment of severe allergic reactions (anaphylaxis). If you experience symptoms of a severe allergic reaction, such as difficulty breathing, swelling of the face or throat, or dizziness, seek immediate medical attention or use an epinephrine auto-injector if prescribed.

By understanding the proper use of Benadryl, its potential risks, and when to seek medical advice, you can effectively manage your allergy symptoms while prioritizing your overall health and safety. Always follow the recommended dosage guidelines and consult with a healthcare professional if you have any concerns about using Benadryl or managing your allergy symptoms.

Diphenhydramine – Benadryl etc – Dosage Table | Health & Wellness Library | University Hospitals Rainbow Babies & Children’s Hospital | Cleveland, OH

Indications:

Treatment of allergic reactions, nasal allergies, hives and itching.

Table Notes:

• AGE LIMITS: For allergies, don’t use under 1 year of age (Reason: it’s a sedative). For colds, not recommended at any age (Reason: no proven benefits) and should be avoided if under 4 years old. Avoid multi-ingredient products in children under 6 years of age (Reason: FDA recommendations 10/2008).
• DOSAGE: Determine by finding child’s weight in the top row of the dosage table
• MEASURING the DOSAGE: Syringes and droppers are more accurate than teaspoons. If possible, use the syringe or dropper that comes with the medication.  If not, medicine syringes are available at pharmacies. If you use a teaspoon, it should be a measuring spoon. Regular spoons are not reliable. Also, remember that 1 level teaspoon equals 5 ml and that ½ teaspoon equals 2.5 ml.
• ADULT DOSAGE: 50 mg
• FREQUENCY: Repeat every six hours as needed
• CHILDREN’S BENADRYL FASTMELTS: Each fastmelt tablet contains the equivalent of 12.5 mg of Diphenhydramine HCL and dosed the same as chewable tablets.

Author and Senior Reviewer: Barton D. Schmitt, M.D.
Content Set: Pediatric HouseCalls Symptom Checker
Pediatric HouseCalls Symptom Checker

How Much Benadryl Can I Take Safely?

Written by
Juhi Modi

Medically reviewed by
HaVy Ngo-Hamilton, Pharm.D.
| May 25, 2022

Benadryl is a common over-the-counter medicine used to relieve symptoms of allergic rhinitis (hay fever) and the common cold, such as runny nose, sneezing, and watery/itchy eyes. It is also used to provide relief from irritated or itchy skin caused by insect bites, hives, eczema, sunburn, and other medical conditions like motion sickness and insomnia. All in all, it has a great variety of uses.

While it is an effective drug, the risk with exemplary over-the-counter medications like Benadryl is that you can easily continue taking it for symptomatic relief without noticing that you are going over the recommended dosage. Doing so can lead to severe side effects. 

This article will discuss the appropriate doses and the risks of taking too much Benadryl.

What is Benadryl?

Brand name Benadryl contains the active ingredient diphenhydramine. It is an over-the-counter antihistamine that helps relieve symptoms of seasonal allergies, the common cold, and itchy skin due to bug bites or allergic reactions. 

Benadryl is available in many different forms, including:

• Oral (to be taken by mouth): tablets, chewable tablets, liquid-filled capsules,liqui-gels, and liquid solution
• Topical (to be applied to the skin): creams, gels, and sprays

Some combination products contain diphenhydramine as the main ingredient along with other ingredients. For example, Benadryl Allergy Plus Congestion for Sinus Pressure & Nasal Congestion Relief contains diphenhydramine, an antihistamine, and phenylephrine, a nasal decongestant.

What is the correct Benadryl dosage?

The correct Benadryl dosage depends on several factors. Among those factors is the condition you’re treating, your age, and the form of Benadryl you’re using. Your physician will advise you to take the lowest effective dose of Benadryl for the shortest possible time as best practice recommends.

Regarding effective Benadryl dosing, commonly used and recommended doses of Benadryl are as follows:

For hay fever, allergies, and common cold symptoms

The recommended dose for adults and children 12 years and older is 25 mg to 50 mg every 4 to 6 hours. 

The recommended dose for children between the ages of 6-12 is 12.5 mg to 25 mg every 4 to 6 hours. 

Children under the age of 6 e should not take oral Benadryl without a doctor’s prescription. 

For itchy skin from insect bites, stings, hives, allergic reactions, or other causes

Adults and children from age 2+ can use the topical form of Benadryl and apply gel, cream, or spray to the affected area up to 4 times daily unless the area is widespread and the oral form is advised by a healthcare professional. Children under 2 years of age should use Benadryl topical products only if advised by a physician.

This is a general dosing guide. Some patients, for example, elderly patients, may need to take lower doses of this medication. If you have any specific questions about Benadryl dosages regarding your age and condition, you should consult your doctor or pharmacist. 

What is the maximum dosage of Benadryl?

The maximum dose of Benadryl for adults and children over 12 years of age is 300 mg per day. The maximum dose of Benadryl for children between the ages of  6 to 12 is 150 mg per day. Do not take more than 6 doses of oral Benadryl in 24 hours. 

Benadryl topical products (creams, gels, sprays) should not be applied to the skin more than 4 times a day.

It is important to check all your other antihistamines and ensure that your other medications don’t contain the same active ingredient, i.e., diphenhydramine. The maximum dose mentioned above is the dose you can safely take from all products and different forms combined.

What are Benadryl’s side effects?

The common side effects of Benadryl include sleepiness, dizziness, headache, dry mouth, dry eyes, and weakness. If these symptoms are severe or do not go away after a few days, talk to your doctor or pharmacist.

Benadryl can also cause more serious side effects, such as problems with cognition (thinking),  memory, fast heartbeat (tachycardia), and seizures. Contact your doctor if you experience these side effects and seek emergency medical care for serious side effects such as seizures. 

What are Benadryl risks and drug interactions?

Benadryl can cause drowsiness, which can impair your ability to drive, operate heavy machinery, or do anything that requires focus. Falling asleep at the wheel can result in accidents, so follow your doctor’s instructions and do not drive while taking Benadryl until you know how this medication affects you.

If you are taking other drugs, talk to a healthcare provider before taking Benadryl to avoid serious drug interactions. For example, taking Benadryl with benzodiazepines (Valium, Xanax, Klonopin) can increase the risk of confusion, drowsiness, and delirium. Mixing Benadryl and alcohol can lead to drowsiness and sedation, increasing the risk of accidents and injuries.

How many days in a row can you take Benadryl?

You should not use over-the-counter (OTC) Benadryl for longer than 7 days as treatment for cold and allergy symptoms. OTC Benadryl is intended for short-term use to provide temporary relief of allergy symptoms. If your symptoms do not improve after a week of Benadryl use, contact your doctor to obtain an accurate diagnosis and discuss alternative treatments.

What happens if you take too much Benadryl?

Scientists do not know a lot about the side effects of taking Benadryl long-term, but it has been linked to conditions such as:

• Constipation
• Weight gain
• Blurred vision
• Hallucinations 
• Memory problems, confusion, dementia
• Restless legs syndrome
• Depression and anxiety
• Tolerance and dependence

Can you overdose on Benadryl?

Yes, you can overdose on Benadryl. Signs and symptoms of a Benadryl overdose may include:

• Confusion
• Blurred vision
• Dry mouth
• Dizziness
• Heart arrhythmia
• Difficulty breathing
• Irritability
• Restlessness
• Confusion
• Hallucinations
• Shock
• Seizures
• Coma
• Death

If you or someone you know may have overdosed on Benadryl, call 911 or seek care at the nearest emergency room without delay.

Wrapping Up: Safe use of over the counter medications like Benadryl

It is not safe to take more than the recommended dosage of over-the-counter medicines like Benadryl. Taking too much Benadryl can cause serious problems, including hallucinations, abnormal heart rhythms, seizures, and even death. Always read the labels on OTC medications carefully and ensure that you take the recommended daily dosage. 

References:

1. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=702f9786-7ce9-43e4-921d-e1db09612127
2. https://medlineplus.