How often can you use a suppository. What are the side effects of using laxative suppositories. How do glycerin suppositories work for constipation relief. When should you consult a doctor about suppository use.

Understanding Glycerin Suppositories: A Quick Solution for Constipation

Glycerin suppositories are a common over-the-counter remedy for occasional constipation. These hyperosmotic laxatives work by drawing water into the intestines, typically resulting in a bowel movement within 15 to 60 minutes after insertion. But how do they compare to other constipation remedies, and when should they be used?

Glycerin suppositories offer a quick solution for those experiencing temporary constipation. However, it’s essential to understand that they are not intended for long-term use. For sustained digestive health, experts recommend focusing on lifestyle changes such as increasing fluid intake, consuming a high-fiber diet, and engaging in regular physical activity.

Normal Bowel Movement Frequency

Before reaching for a suppository, it’s crucial to understand what constitutes normal bowel movement frequency:

• Adults: Once daily to 1-2 times weekly
• Preschool-aged children: Once daily to once every other day

Deviations from these patterns don’t always indicate constipation, as individual variations are common. However, if you’re experiencing discomfort or a significant change in your usual pattern, it may be time to consider treatment options.

Proper Usage of Glycerin Suppositories: Step-by-Step Guide

Using a glycerin suppository correctly is crucial for its effectiveness and your comfort. Here’s a detailed guide on how to use adult suppositories:

1. Wash your hands thoroughly before and after use.
2. If the suppository is too soft, chill it in the refrigerator for 30 minutes or run cold water over it before removing the foil wrapper.
3. Remove the foil wrapper if present.
4. You may moisten the suppository with lukewarm water if desired, but avoid using petroleum jelly or mineral oil as these can reduce effectiveness.
5. Lie on your left side with your right knee slightly bent.
6. Gently insert the suppository into the rectum, pointed end first, using your finger.
7. Stay in this position for 15 to 20 minutes if possible, or until you feel a strong urge to have a bowel movement.

For children, the process is similar, but they should lie on their side with the lower leg straightened and the upper leg bent toward the stomach. After insertion, hold the child’s buttocks together for a few seconds to prevent the suppository from coming out.

Frequency of Use: How Often is Too Often?

Are you wondering about the safe frequency of suppository use? Generally, it’s recommended not to use glycerin suppositories more than once daily unless directed by a healthcare professional. Overuse can lead to several problems:

• Loss of normal bowel function
• Laxative dependence
• Dehydration
• Electrolyte imbalances

If you find yourself needing to use suppositories frequently, it’s time to consult with a healthcare provider. They can help identify underlying causes of chronic constipation and suggest more sustainable treatment options.

Potential Side Effects and Precautions

While glycerin suppositories are generally safe when used as directed, they can cause some side effects. Being aware of these potential issues can help you use the product more safely and know when to seek medical attention.

Common Side Effects

Some users may experience:

• Rectal irritation or burning sensation
• Abdominal discomfort or cramps
• Small amounts of mucus in the stool

These effects are usually mild and transient. However, if they persist or worsen, it’s advisable to consult a healthcare provider.

Serious Side Effects Requiring Medical Attention

Seek immediate medical help if you experience:

• Severe or persistent abdominal pain
• Bloody stools
• Rectal bleeding
• Signs of dehydration (unusual decreased urination, dry mouth, fast heartbeat, dizziness)
• Symptoms of a serious allergic reaction (rash, itching/swelling, severe dizziness, trouble breathing)

Precautions Before Use

Before using glycerin suppositories, inform your healthcare provider if you have:

• Allergies to any ingredients in the product
• A history of rectal bleeding
• Intestinal blockage or other bowel problems
• Ulcerative colitis
• Hemorrhoids
• Persistent stomach/abdominal symptoms

Additionally, consult a doctor before use if you’ve experienced a sudden change in bowel habits lasting more than two weeks or if you need to use laxatives for more than one week.

Alternatives to Glycerin Suppositories for Constipation Relief

While glycerin suppositories can provide quick relief, they’re not the only option for managing constipation. Consider these alternatives:

Lifestyle Changes

• Increase fluid intake, especially water
• Add more fiber to your diet through fruits, vegetables, and whole grains
• Engage in regular physical activity
• Establish a regular bathroom routine

Other Over-the-Counter Options

• Stool softeners
• Osmotic laxatives
• Bulk-forming laxatives
• Lubricant laxatives

Each of these options works differently and may be more suitable depending on your specific situation. Consult with a healthcare provider to determine the best approach for your needs.

When to Seek Medical Attention for Constipation

While occasional constipation is common, certain symptoms warrant prompt medical attention. Consult a healthcare provider if you experience:

• Severe abdominal pain
• Blood in your stool
• Unexplained weight loss
• Persistent constipation despite using laxatives
• A significant change in bowel habits lasting more than two weeks

These symptoms could indicate a more serious underlying condition that requires professional evaluation and treatment.

The Role of Diet in Preventing Constipation

A balanced diet plays a crucial role in maintaining regular bowel movements and preventing constipation. Here are some dietary tips to promote digestive health:

Fiber-Rich Foods

Incorporate these high-fiber foods into your daily diet:

• Fresh fruits (e.g., apples, pears, berries)
• Vegetables (e.g., broccoli, carrots, spinach)
• Whole grains (e.g., oatmeal, brown rice, quinoa)
• Legumes (e.g., lentils, beans, chickpeas)
• Nuts and seeds

Aim for 25-30 grams of fiber daily for adults. Increase your fiber intake gradually to avoid gas and bloating.

Hydration

Adequate fluid intake is essential for preventing constipation. Water helps soften stools and promotes regular bowel movements. Aim for:

• 8-10 cups (64-80 ounces) of water daily for most adults
• More if you’re physically active or in hot weather

Other hydrating options include herbal teas, clear broths, and water-rich fruits and vegetables.

Foods to Limit

Some foods may contribute to constipation. Consider reducing your intake of:

• Processed foods high in refined carbohydrates
• Dairy products (for some individuals)
• Red meat
• Fried foods
• Alcohol

Remember, dietary changes take time to show effects. Be patient and consistent with your new eating habits for the best results.

Exercise and Its Impact on Digestive Health

Regular physical activity is a key component in maintaining healthy bowel function and preventing constipation. Here’s how exercise can benefit your digestive system:

Benefits of Exercise for Digestion

• Stimulates intestinal contractions, promoting regular bowel movements
• Reduces transit time of food through the digestive system
• Helps maintain a healthy body weight, reducing the risk of obesity-related digestive issues
• Reduces stress, which can negatively impact digestive function

Recommended Exercise Routine

For optimal digestive health, aim for:

• At least 150 minutes of moderate-intensity aerobic activity per week
• Strength training exercises at least twice a week
• Daily walks or light activities to keep your body moving

Remember to start slowly if you’re new to exercise and gradually increase your activity level. Always consult with a healthcare provider before starting a new exercise regimen, especially if you have any existing health conditions.

Specific Exercises for Digestive Health

While any form of physical activity can benefit your digestive system, some exercises may be particularly helpful:

• Brisk walking
• Jogging or running
• Swimming
• Cycling
• Yoga (especially poses that target the abdominal area)
• Pilates

Incorporating a variety of these activities into your routine can help maintain regular bowel movements and overall digestive health.

The Importance of Proper Hydration for Digestive Health

Adequate hydration is crucial for maintaining healthy bowel function and preventing constipation. Water plays a vital role in softening stools and promoting regular bowel movements. Here’s why hydration matters and how to ensure you’re getting enough fluids:

How Water Affects Digestion

• Softens stool, making it easier to pass
• Helps dissolve nutrients for better absorption
• Supports the mucosal lining of the intestines
• Aids in the transportation of waste products through the digestive system

Signs of Dehydration

Be aware of these indicators that you may not be drinking enough water:

• Dark yellow or amber-colored urine
• Dry mouth and lips
• Fatigue
• Headaches
• Decreased urine output
• Constipation

Tips for Staying Hydrated

To ensure proper hydration:

• Carry a reusable water bottle with you throughout the day
• Set reminders to drink water regularly
• Flavor water with fresh fruits or herbs if you find plain water unappealing
• Eat water-rich foods like cucumbers, watermelon, and zucchini
• Limit caffeine and alcohol intake, as these can contribute to dehydration

Remember, individual hydration needs can vary based on factors such as activity level, climate, and overall health. Listen to your body and adjust your fluid intake accordingly.

Adult Suppositories Rectal: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Uses

This product is used to relieve occasional constipation. Glycerin belongs to a class of drugs known as hyperosmotic laxatives. It works by drawing water into the intestines. This effect usually results in a bowel movement within 15 to 60 minutes.For adults, the normal frequency of bowel movements varies from once daily to 1 to 2 times weekly. For preschool-aged children, the normal frequency of bowel movements varies from once daily to once every other day. Constipation is best treated by drinking plenty of fluids, eating foods high in fiber, and exercising regularly.

How to use Adult Suppositories Suppository

This product is for rectal use only. Read and follow all directions on the product package, or use as directed by your doctor. If you have any questions, ask your doctor or pharmacist. If the suppository is too soft to insert, chill in the refrigerator for 30 minutes or run cold water over it before removing the foil wrapper.

Wash your hands before and after using this product. If the medication is wrapped in foil, remove the foil wrapper. If desired, the suppository may be moistened with lukewarm water. Do not use petroleum jelly or mineral oil. Doing so may cause the product to be less effective.

Lie on your left side with the right knee slightly bent. Using your finger, gently insert the suppository well up into the rectum, pointed end first. After insertion, stay in position for 15 to 20 minutes if possible until you feel a strong urge to have a bowel movement. This product does not need to melt completely to produce an effect. If you are helping a child use this product, have the child lie on their side with the lower leg straightened out and the upper leg bent toward the stomach. Using your finger, gently insert the suppository into the rectum, pointed end first. Hold the buttocks together for a few seconds. Then, have your child stay lying down for 15 to 20 minutes if possible to keep the suppository from coming out.

Do not use this product more than once daily unless otherwise directed by your doctor.

If this product is used too frequently, it may cause loss of normal bowel function and an inability to have a bowel movement without using the product (laxative dependence). If you notice symptoms of overuse, such as diarrhea, abdominal pain, decreased weight, or weakness, contact your doctor promptly.

Consult your doctor promptly if you do not have a bowel movement after using this product or if you think you may have a serious medical problem.

Side Effects

Rectal irritation/burning, abdominal discomfort/cramps, or small amounts of mucus in the stool may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

If your doctor has directed you to use this product, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this product do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: abdominal pain that is severe or doesn’t go away, bloody stools, rectal bleeding.

Diarrhea that doesn’t stop may result in dehydration. Contact your doctor promptly if you notice any symptoms of dehydration, such as unusual decreased urination, unusual dry mouth/thirst, fast heartbeat, or dizziness/lightheadedness.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before using glycerin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: rectal bleeding, intestinal blockage (obstruction), other bowel problems (such as ulcerative colitis, hemorrhoids), current stomach/abdominal symptoms (such as nausea/vomiting that doesn’t stop, pain, cramping).

Consult your doctor before using this product if you have had a sudden change in bowel habits lasting more than 2 weeks or if you need to use a laxative for more than 1 week. These could be symptoms of a serious medical problem.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

Does Adult Suppositories Suppository interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose

This medicine may be harmful if swallowed. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Keep all medical and lab appointments.

Not applicable.

Refer to storage information on the package label. Protect from high heat. Do not store in the bathroom. If you have any questions about storage, ask your pharmacist. Keep all drug products away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

What They Treat and How to Use Them

Written by Stephanie Watson

• Types of Suppositories
• Why Use Them
• How to Insert Them
• Problems You Might Have

Medicine can get into your body in a few different ways. You can swallow a pill, drink a liquid, or get a shot. A suppository is another way to deliver a drug. It’s a small, round or cone-shaped object that you put in your body, often into your bottom. Once it’s inside, it melts or dissolves and releases its medication.

Suppositories may not be the most pleasant product you’ll ever use. But they can make it easier to take medicine that you can’t swallow or that your stomach or intestines wouldn’t absorb well.

Suppositories have a base made from substances like gelatin or cocoa butter that surrounds the drug. As the warmth of your body melts the outside, the drug slowly releases.

Different types of suppositories go into the rectum, vagina, or the duct that empties your bladder, called the urethra. Sometimes they treat the area where you put them in. Or the medicine absorbs into your blood and travels to other parts of your body.

Rectal suppositories go in your bottom. They are about an inch long and have a rounded or bullet-shaped tip. You might take them to treat:

• Allergies
• Anxiety
• Constipation
• Fever
• Hemorrhoids
• Motion sickness
• Nausea
• Pain and itching
• Seizures
• Mental health problems, such as schizophrenia or bipolar disorder

Vaginal suppositories are oval-shaped. You can use them for:

• Bacterial or fungal infections
• Vaginal dryness
• Birth control

Urethral suppositories are rare. There’s only one kind, MUSE, which men with erection problems can use to take the drug alprostadil. The suppository is about the size of a grain of rice.

You might need a suppository if:

• The drug you’re taking would break down too quickly in your digestive tract if you took it as a pill or liquid.
• You can’t swallow medicine.
• You’re vomiting and can’t keep a pill or liquid down.
• The medicine tastes too bad to take by mouth.

To put in a rectal suppository:

• Go to the bathroom first to try to empty your colon.
• Wash your hands with soap and warm water.
• Unwrap the suppository.
• Rub a water-based lubricant over the tip or dip it in water. It will help you slide it in smoothly.
• Get in a comfortable position. You can stand with one leg up on a chair or lie on your side with one leg straight and the other bent in toward your stomach.
• Gently spread your buttocks open.
• Carefully push the suppository, tapered end first, about 1 inch into your bottom.
• Close your legs and sit or lie still for about 15 minutes to let it dissolve.
• Wash your hands again with warm water and soap.

To put a suppository into your vagina:

• Wash your hands with soap and warm water.
• Unwrap the suppository and put it into the applicator.
• Lie on your back with your knees bent toward your chest, or stand with your knees bent and your feet a few inches apart.
• Gently put the applicator into your vagina as far is it will go without feeling uncomfortable.
• Press on the plunger at the end of the applicator to push the suppository in, then remove the applicator.
• Lie down for a few minutes to let the medicine absorb.
• Wash your hands again with soap and warm water.

Vaginal suppositories can be messy, so you may want to wear a pad for a little while after you put one in.

To put in a urethral suppository:

• Go to the bathroom to empty your bladder.
• Remove the cover from the applicator.
• Stretch your penis to its full length to open the urethra, and put the applicator into the hole at the tip.
• Gently push the button at the top of the applicator until it stops. Hold it there for 5 seconds.
• Sway the applicator from side to side to make sure the suppository has gone in.
• Pull out the applicator. Make sure there’s no more medicine in it.
• While your penis is still pulled out, massage it firmly between your hands for at least 10 seconds to help the medicine absorb.

Suppositories are usually safe. Yet there can be some problems when you take medicine this way:

• Some of the medicine might leak back out.
• Sometimes your body doesn’t absorb the drug as well as if you took it by mouth.
• The medicine can irritate the spot where you put it in.

Ask your doctor before you use a suppository if you:

• Have an irregular heartbeat
• Have had recent surgery on your rectum
• Are a man who’s had prostate surgery recently
• Are a woman who’s had surgery or radiation treatment to your vaginal area

Top Picks

Suppositories (candles) Longidaza® 3000 ME

Admission schemes

In urology

In inflammatory diseases of the prostate gland

Dose

1 suppository

Frequency

Every other day

Duration

10 rectal injections

Then

Dose

1 suppository

Frequency

After 2 days

Duration

10 rectal injections

In gynecology

In inflammatory diseases of the pelvic organs

Dose

1 suppository

Frequency

After 2 days

Duration

From 10 injections rectally or vaginally

INSTRUCTIONS FOR USE FOR LONGIDASE

^®
VAGINAL AND RECTAL SUPPOSITORIES 3000 ME

Registration number:

LSR-002940/07

Trade name:

Longidase ^®

International Nonproprietary Name:

Bovhyaluronidase azoximer (bovhyaluronidasum azoximerum)

Chemical name:

Hyaluronidase N-oxide Copolymer Conjugate
1,4-ethylenepiperazine and (N-carboxymethyl)-1,4-ethylenepiperazinium bromide

Dosage form:

Vaginal and rectal suppositories

Description:

Torpedo-shaped suppositories, light yellow
with a slight specific smell of cocoa butter, marbling is allowed.

Pharmacotherapeutic group:

Enzyme

ATX code:

V03AX

Composition per suppository:

Active ingredient:

Bovhyaluronidase azoximer (Longidase ^® ) – 3000 IU

Excipient:

Cocoa butter – to obtain a suppository weighing 1.3 g

PHARMACODYNAMICS

Longidase ^® has hyaluronidase (enzymatic) activity
prolonged action, chelating, antioxidant, immunomodulatory and moderately
pronounced anti-inflammatory properties.

The prolongation of the action of the enzyme is achieved by covalent binding of the enzyme to
physiologically active polymer carrier (azoxymer). Longidase ^® exhibits anti-fibrotic properties,
weakens the course of the acute phase of inflammation, regulates (increases or decreases depending on the initial
level) synthesis of inflammatory mediators (interleukin-1 and tumor necrosis factor-alpha), increases
humoral immune response and body resistance to infection.

Pronounced antifibrotic properties of Longidase ^® provided by hyaluronidase conjugation
with a carrier, which significantly increases the resistance of the enzyme to denaturing effects and action
inhibitors: the enzymatic activity of Longidase ^® is preserved when heated to 37 ° C for 20 days,
while native hyaluronidase under the same conditions loses its activity during the day. IN
Longidase ^® ensures the simultaneous local presence of the hyaluronidase enzyme and the carrier,
capable of binding enzyme inhibitors and stimulants released during hydrolysis of matrix components
collagen synthesis (iron, copper, heparin, etc.). Due to the indicated properties of Longidase ^® has no
only the ability to depolymerize the connective tissue matrix in fibrous-granulomatous formations,
but also to suppress the reverse regulatory reaction aimed at the synthesis of connective tissue components.

Glycosaminoglycans are specific substrates for testicular hyaluronidase
(hyaluronic acid, chondroitin, chondroitin-4-sulfate, chondroitin-6-sulfate), which form the basis of the matrix
connective tissue. As a result of depolymerization (breaking the bond between C ₁ acetylglucosamine and
With ₄ glucuronic or induronic acids) glycosaminoglycans change their basic properties:
viscosity decreases, the ability to bind water, metal ions decreases, temporarily increases
permeability of tissue barriers, facilitates the movement of fluid in the intercellular space, increases
elasticity of the connective tissue, which manifests itself in a decrease in tissue swelling, flattening of scars,
increasing the range of motion of the joints, reducing contractures and preventing their formation, reducing
adhesion process. Biochemical, immunological, histological and electron microscopy
studies have shown that Longidase ^® does not damage normal connective tissue, but causes destruction
changed in composition and structure of the connective tissue in the area of ​​fibrosis.

Longidase ^® is non-mutagenic, embryotoxic, teratogenic and carcinogenic
action.

The drug is well tolerated by patients, no local and general allergic reactions were noted.
reactions.

The use of Longidase ^® at therapeutic doses during or after surgical treatment is not
causes deterioration of the course of the postoperative period or progression of the infectious process; Not
slows down bone regeneration.

PHARMACOKINETICS

An experimental study of pharmacokinetics made it possible to establish
that when administered rectally, Longidaza ^® is characterized by a high rate of distribution in
organism, is well absorbed into the systemic circulation and reaches the maximum concentration in the blood
After 1 hour.

Half-life of about 0.5 hours, elimination half-life of 42 to 84 hours.

Excreted primarily by the kidneys.

The drug penetrates into all organs and tissues, including passing through
blood-brain and blood-ophthalmic barriers. The absence of tissue cumulation was established.

The bioavailability of Longidase ^® when administered rectally is high: about 90%.

Indications for use

Adults and adolescents over 12 years of age as monotherapy and as part of
complex therapy of diseases accompanied by connective tissue hyperplasia, including
against the background of the inflammatory process:

• in urology:
  chronic prostatitis, interstitial cystitis, strictures of the urethra and ureters, Peyronie’s disease,
  the initial stage of benign prostatic hyperplasia, prevention of scarring and
  strictures after surgical interventions on the urethra, bladder, ureters;
• in gynecology:
  adhesive process (prevention and treatment) in the small pelvis in chronic inflammatory diseases
  internal genital organs, after gynecological manipulations, including artificial abortions,
  previous surgical interventions on the pelvic organs; intrauterine synechia,
  tubal-peritoneal infertility, chronic endomyometritis;
• in dermatovenereology:
  limited scleroderma, prevention of fibrotic complications of sexually transmitted infections;
• in surgery:
  prevention and treatment of adhesions after surgical interventions on the abdominal organs;
  long-term non-healing wounds;
• in pulmonology and phthisiology:
  pneumofibrosis, siderosis, tuberculosis (cavernous fibrous, infiltrative, tuberculoma), interstitial
  pneumonia, fibrosing alveolitis, pleurisy;
• to increase the bioavailability of antibiotic therapy
  in urology, gynecology, dermatovenereology, surgery, pulmonology, etc.

CONTRAINDICATIONS

• hypersensitivity to hyaluronidase-based drugs
• pulmonary hemorrhage and hemoptysis
• fresh vitreous hemorrhage
• malignant neoplasms

• acute renal failure
• children under 12 years of age (results of clinical trials
  missing)
• pregnancy and lactation

Use with caution

Use with caution no more than once a week in patients with chronic renal
insufficiency, history of pulmonary bleeding.

PREGNANCY AND BREASTFEEDING

Contraindicated during pregnancy and breastfeeding
(no clinical experience).

Dosage and administration

Longidase ^® suppositories 3000 IU is recommended for rectal or
vaginal application once a day at night with a course of 10 to 20 injections.

Adolescents aged 12 to 18

suppositories are administered rectally only.

Adults and adolescents over 12 years of age rectally:

1 suppository 1 time per day after bowel cleansing.

Adult vaginal:

1 suppository 1 time per day (at night) the suppository is introduced into
vagina in the supine position.

The scheme of administration is adjusted depending on the severity, stage and
disease duration:

Longidaza ^® is administered every other day or with breaks of 2-3 days.

Recommended regimens and doses:

In urology

Dose

1 suppository

Frequency

Every other day

Duration

10 rectal injections

Then

Dose

1 suppository

Frequency

After 2 days

Duration

10 rectal injections

In gynecology

Dose

1 suppository

Frequency

After 2 days

Duration

From 10 injections rectally or vaginally

In pulmonology and phthisiology

Dose

1 suppository

Frequency

After 2-4 days

Duration

10-20 rectal injections

In surgery

Dose

1 suppository

Frequency

After 2-3 days

Duration

10 rectal injections

In dermatovenereology

Dose

1 suppository

Frequency

After 1-2 days

Duration

10-15 rectal injections

If necessary, a second course of the drug is recommended
Longidase ^® not earlier than three months or long-term maintenance therapy 1 each
suppository 1 time in 5-7 days for 3-4 months.

By-effect

The frequency of adverse reactions is presented as follows
classification: very common ≥ 10%; frequent ≥ 1% and < 10%; infrequent ≥ 0.1% and < 1%; rare ≥ 0.01% and < 0.1%; very rare <0.001%.

Very rare:
local reactions in the form of redness, swelling, itching of the perianal zone, vaginal itching due to
individual sensitivity to the components of the drug.

overdose

Overdose symptoms may include chills,
fever, dizziness, hypotension. The drug is stopped and
prescribe symptomatic therapy.

INTERACTION WITH OTHER DRUGS
MEANS

Longidase ^® can be combined with antibiotics
antiviral, antifungal drugs, bronchodilators. When administered in combination
with other drugs (antibiotics, local anesthetics, diuretics) should be
take into account the possibility of increasing bioavailability and enhancing their action.

When combined with high doses of salicylates, cortisone,
adrenocorticotropic hormone (ACTH), estrogens, or antihistamines may be reduced
enzymatic activity of Longidase ^® . Do not use Longidase ^®
simultaneously with drugs containing furosemide, benzodiazepines, phenytoin.

special instructions

When taking the drug, strictly follow the instructions in
instructions instructions. If you have any questions, please contact your
doctor or pharmacist.

• Discontinue use of Longidaza ^® if an allergic reaction develops.
• When used against the background of exacerbation of foci of infection to prevent the spread of infection
  must be prescribed under the cover of antimicrobial agents.
• If an adverse reaction occurs, or if an adverse reaction occurs that is not mentioned in
  instructions for medical use, you must consult your doctor.
• Do not use the drug if there are visual signs of its unsuitability (packaging defect,
  discoloration of the suppository).
• In case of missing the next dose of the drug, continue to use it as usual (do not administer
  double dose).
• If it is necessary to stop taking Longidase ^® , it can be canceled immediately, without
  gradual dose reduction.

IMPACT ON THE ABILITY TO DRIVE TRANSPORT
MEANS, MECHANISMS

The use of Longidase ^® does not affect the ability
driving vehicles, servicing mechanisms and other types of work requiring
increased concentration of attention and speed of psychomotor reactions.

Release form

Vaginal and rectal suppositories 3000 IU.

5 suppositories in a blister pack made of PVC film.
One, two or four blister packs in a carton pack along with instructions for
application.

Storage conditions

In a dry place protected from light at a temperature of 2 to 15 °C.
Keep away from children.

expiration date

2 years. Do not use after the expiry date stated
on the package.

vacation conditions

Released without a prescription.

Legal entity in whose name the registration certificate was issued

Marketing authorization holder and manufacturer:
NPO Petrovax Pharm LLC

Registered address / Consumer claims address:
Russian Federation, 142143, Moscow region, Podolsky district, s. Pokrov, st. Sosnovaya, d. 1,
tel./fax: (495) 926-21-07, E-mail: [email protected]; for claims: tel.: (495)
730-75-45, E-mail: [email protected]

Production / Packaging (primary packaging):
Russian Federation, 115598, Moscow, st. Zagoryevskaya, 10, bldg. 4, tel./fax: (495)
329-17-18.

Secondary (consumer) packaging / Release quality control:
Russian Federation, 142143, Moscow region, Podolsky district, s. Pokrov, st. Sosnovaya, d. 1,
tel./fax: (495) 926-21-07.

How to insert candles correctly? – Fitoleum

If you have never used suppositories before or want to be sure that they are used correctly, then this article will help you figure out how to insert candles correctly.

Suppositories (candles) are bullet-shaped medicines for rectal (i.e. through the anus into the rectum) or vaginal administration. Used for local exposure to pathologies of the pelvic organs (hemorrhoids, cystitis, etc.). Unlike the oral method, suppositories bypass the gastrointestinal tract, which allows the drug to have a faster and more effective effect on inflammation.

What do you need to know?

1. Candles melt at body temperature. Store them in a dry place at a temperature not exceeding 18 ° C, preferably in the refrigerator. Open and remove the suppository is immediately before the introduction procedure.
2. A distinction is made between rectal and vaginal suppositories. The possibilities of using suppositories for certain diseases should be studied in the instructions for the drug. For example, our company Fitoleum produces Fitoleum cream sticks and Fitoleum Kyzylmay suppositories, which can be used both rectally and vaginally.
3. Be sure to read the composition and instructions inside the package. Make sure you are not allergic to any of the ingredients. If in any doubt, consult a doctor.

How to use suppositories?

1. Since suppositories melt at body temperature and may leak out soon, be prepared to lie down for at least 20 minutes to be effective. That is why candles are more often used before bedtime. Use a pad or paper towel to avoid staining your laundry.
2. Go to the toilet and do hygiene without the use of soap and other detergents, only water.
3. Manipulation is done by hand, so wash thoroughly or use a fingertip or glove.
4. Tear or cut off one suppository pack.
5. To open the package, from the pointy end of the candle, pull the “lugs” in different directions, as shown in the picture.
6. Depending on the disease, slowly insert the suppository (sharp end) into the anus or into the vagina as far as possible. For some, it is more convenient to do this in the supine position, for others – standing, placing one foot on a chair and crouching slightly.
7. That’s it. Take a lying position. The suppository will melt and be absorbed. After you get up, remove any excess with a tissue or warm water.

Frequently Asked Questions

Does it hurt to insert rectally/vaginally?

No, it shouldn’t hurt. The size of the candle is usually smaller than even the little finger of the hand. In addition, for example, Fitoleum cream stick contains cocoa butter and medicinal herbs, which make the process of drug administration even easier and painless.

Candles are leaking. Is it normal? What good are they if they leak?

The purpose of using suppositories is to ensure that the drug contained in them bypasses the digestive system, retains its properties and concentration, and has a local effect and a therapeutic effect as soon as possible.

It is normal for them to run out and not completely absorb because they contain wax. As a result of the introduction of a candle, the medicine is absorbed, and the wax, which melts at body temperature, is not absorbed by the mucous membrane and comes out. That is why it is recommended to use pads during the procedure, and for the first 20 minutes after the injection, take a horizontal position – so that everything does not immediately leak out and the medicine is absorbed.

Do I need to do a cleansing enema before inserting a suppository?

Before inserting the suppository into the anus, it is necessary to have a bowel movement. If the patient fails to spontaneously empty the intestines, then an enema should be administered.

How long to walk with candles inside? Does it need to be pulled back?

“Walking” is not worth it. It is better to be in the supine position for at least 20 minutes after the administration of the suppository. You can also insert a candle before going to bed and “leave” it inside for the whole night. There is no need to get it back – it will melt, and the excess will flow out.

Can candles be inserted during menstruation?

If there are no contraindications or other comments regarding the use of suppositories during menstruation in the instructions for the drug, then you can.

Can suppositories be used during pregnancy?

Depends on the drug. Read the instructions, it must indicate this point. For example, Fitoleum cream sticks and Fitoleum Kyzylmay suppositories can be taken during pregnancy and lactation.

Can I be allergic to suppositories?

Yes.