Is clindamycin good for sinus infections. Clindamycin for Sinus Infections: Efficacy, Usage, and Precautions
How effective is clindamycin in treating sinus infections. What are the potential side effects of using clindamycin for sinusitis. How long does it take for clindamycin to work against sinus infections. What precautions should be taken when using clindamycin for sinusitis.
Understanding Clindamycin: An Antibiotic for Sinus Infections
Clindamycin is a powerful antibiotic belonging to the lincosamide family of drugs. It has gained popularity in treating various bacterial infections, including sinusitis. This medication works by inhibiting bacterial protein synthesis, effectively stopping the growth and reproduction of harmful microorganisms.
Sinus infections, or sinusitis, can be a debilitating condition causing severe headaches, facial pressure, and fatigue. When caused by bacteria, antibiotics like clindamycin can provide much-needed relief. But how effective is this medication for sinus infections specifically?
How does clindamycin combat sinus infections?
Clindamycin targets the bacteria responsible for sinus infections by:
- Interfering with bacterial protein production
- Preventing bacterial growth and reproduction
- Allowing the immune system to effectively fight off the infection
- Reducing inflammation in the sinus cavities
This multi-faceted approach makes clindamycin an effective choice for treating bacterial sinusitis, especially in cases where other antibiotics have proven ineffective.
Efficacy of Clindamycin in Treating Sinus Infections
Research has shown that clindamycin can be highly effective in treating acute bacterial sinusitis. Studies indicate that a 10-day course of clindamycin often resolves the infection without the need for additional antibiotics. This makes it an attractive option for both patients and healthcare providers.
What makes clindamycin stand out among other antibiotics?
Clindamycin offers several advantages in treating sinus infections:
- Broad-spectrum activity against various bacteria
- Lower risk of antibiotic resistance
- Reduced likelihood of causing bacterial overgrowth
- Effectiveness against certain antibiotic-resistant strains
These factors contribute to clindamycin’s growing popularity as a treatment option for sinusitis, particularly in cases where other antibiotics have failed to provide relief.
Dosage and Administration of Clindamycin for Sinus Infections
The proper dosage and administration of clindamycin are crucial for its effectiveness in treating sinus infections. While the exact dosage may vary depending on the severity of the infection and individual patient factors, there are general guidelines to follow.
What is the typical dosage of clindamycin for sinus infections?
For adults, the usual dosage of clindamycin for sinus infections is:
- 150-300 mg orally every 6 hours
- 300-450 mg orally every 8 hours
The duration of treatment typically ranges from 7 to 14 days, depending on the severity of the infection and the patient’s response to the medication. It’s crucial to complete the entire course of antibiotics as prescribed, even if symptoms improve before finishing the medication.
Potential Side Effects and Precautions of Using Clindamycin
While clindamycin is generally well-tolerated, like all medications, it can cause side effects in some individuals. Being aware of these potential side effects and taking necessary precautions can help ensure a safe and effective treatment experience.
What are the common side effects of clindamycin?
The most frequently reported side effects of clindamycin include:
- Nausea and vomiting
- Diarrhea
- Abdominal pain or discomfort
- Skin rash or itching
- Yeast infections
While these side effects are usually mild and resolve on their own, it’s important to consult a healthcare provider if they persist or worsen. In rare cases, clindamycin can cause more serious side effects, such as severe allergic reactions or Clostridium difficile-associated diarrhea (CDAD).
What precautions should be taken when using clindamycin?
To minimize the risk of adverse effects and ensure the best possible outcome, consider the following precautions:
- Inform your healthcare provider about any allergies or medical conditions
- Disclose all medications and supplements you’re currently taking
- Avoid alcohol consumption during treatment
- Take probiotics to maintain gut health and reduce the risk of antibiotic-associated diarrhea
- Complete the full course of antibiotics as prescribed
By following these precautions and staying vigilant for any unusual symptoms, patients can maximize the benefits of clindamycin while minimizing potential risks.
Clindamycin vs. Other Antibiotics for Sinus Infections
While clindamycin has proven effective in treating sinus infections, it’s not the only antibiotic option available. Understanding how clindamycin compares to other commonly prescribed antibiotics can help patients and healthcare providers make informed decisions about treatment.
How does clindamycin compare to amoxicillin for sinus infections?
Amoxicillin is often considered the first-line treatment for bacterial sinusitis. However, clindamycin may be preferred in certain situations:
- When patients are allergic to penicillin-based antibiotics
- In cases of antibiotic-resistant infections
- When amoxicillin has failed to resolve the infection
Clindamycin’s broader spectrum of activity and effectiveness against certain resistant strains make it a valuable alternative to amoxicillin in these scenarios.
What advantages does clindamycin offer over other antibiotics?
Clindamycin offers several benefits compared to other antibiotics:
- Lower risk of developing antibiotic resistance
- Effective against a wide range of bacteria
- Good penetration into sinus tissues
- Option for patients with penicillin allergies
These advantages make clindamycin a versatile choice for treating sinus infections, particularly in cases where other antibiotics have proven ineffective or unsuitable.
Duration of Treatment and Expected Results
Understanding the typical duration of treatment and expected results when using clindamycin for sinus infections can help patients manage their expectations and adhere to the prescribed regimen.
How long does it take for clindamycin to work on sinus infections?
The timeline for improvement can vary depending on individual factors, but generally:
- Patients may start to feel better within 2-3 days of starting treatment
- Significant improvement is often seen within 5-7 days
- Complete resolution of symptoms typically occurs by the end of the 10-14 day treatment course
It’s important to note that while symptoms may improve relatively quickly, completing the entire course of antibiotics is crucial to prevent the recurrence of infection and the development of antibiotic-resistant bacteria.
What factors can influence the effectiveness of clindamycin treatment?
Several factors can impact how well clindamycin works for sinus infections:
- The specific bacteria causing the infection
- The severity and duration of the infection
- The patient’s immune system function
- Adherence to the prescribed dosage and duration
- Presence of underlying health conditions
By considering these factors and working closely with a healthcare provider, patients can optimize their treatment outcomes and achieve faster relief from sinus infection symptoms.
Complementary Treatments and Lifestyle Modifications
While clindamycin can effectively combat the bacterial cause of sinus infections, complementary treatments and lifestyle modifications can enhance the healing process and provide additional symptom relief.
What additional treatments can support clindamycin therapy for sinus infections?
Consider incorporating the following supportive measures:
- Nasal saline irrigation to flush out mucus and irritants
- Over-the-counter pain relievers for headache and facial pain
- Decongestants to reduce nasal congestion
- Humidifiers to add moisture to the air and soothe irritated sinuses
- Warm compresses applied to the face to alleviate pressure and pain
These complementary treatments can work synergistically with clindamycin to provide faster and more comprehensive relief from sinus infection symptoms.
What lifestyle changes can help prevent future sinus infections?
To reduce the risk of recurrent sinus infections, consider implementing these lifestyle modifications:
- Practice good hand hygiene to prevent the spread of bacteria and viruses
- Avoid known allergens and irritants that can trigger sinus inflammation
- Stay hydrated to keep nasal passages moist and promote mucus drainage
- Use a humidifier in dry environments to prevent sinus irritation
- Quit smoking or avoid exposure to secondhand smoke
- Manage underlying conditions like allergies or asthma effectively
By combining these preventive measures with appropriate antibiotic treatment when necessary, individuals can significantly reduce their risk of developing chronic or recurrent sinus infections.
When to Seek Medical Attention
While clindamycin is often effective in treating sinus infections, there are situations where additional medical attention may be necessary. Recognizing these scenarios can help ensure timely and appropriate care.
What signs indicate that a sinus infection may be worsening despite antibiotic treatment?
Be alert for the following warning signs:
- Persistent or worsening fever after 3-5 days of treatment
- Severe headache or facial pain that doesn’t respond to over-the-counter pain relievers
- Visual disturbances or eye swelling
- Confusion or altered mental state
- Neck stiffness or severe ear pain
If any of these symptoms occur, it’s crucial to seek immediate medical attention, as they may indicate complications or the need for alternative treatment approaches.
When should patients consider alternative treatments for sinus infections?
Alternative treatments or further medical evaluation may be necessary if:
- Symptoms persist or worsen after completing a full course of clindamycin
- Recurrent sinus infections occur despite appropriate antibiotic therapy
- Severe side effects develop from clindamycin use
- Underlying conditions, such as nasal polyps or structural abnormalities, are suspected
In these cases, healthcare providers may recommend additional diagnostic tests, alternative antibiotics, or even surgical interventions to address the underlying causes of persistent or recurrent sinus infections.
By understanding the proper use of clindamycin, recognizing potential side effects, and knowing when to seek additional medical care, patients can effectively manage sinus infections and minimize their impact on daily life. Always consult with a healthcare professional for personalized advice and treatment recommendations tailored to your specific situation.
Can You Use Clindamycin for Sinus Infection?
This article is a comprehensive guide to using clindamycin for sinus infection. Read on to learn helpful information about the potential risks, benefits, dosage instructions, and more so that you can make a knowledgeable decision when deciding whether or not this drug is right for you.
Sinusitis can be a painful and debilitating experience. Not only does the unbearable pressure cause severe headaches, but it can also lead to fatigue and even fever if left untreated.
The best way to relieve sinusitis pain is often through antibiotic therapy like clindamycin. But what exactly is clindamycin, how effective is it for treating sinusitis, and are there any side effects associated with using this drug?
What Is clindamycin?
Clindamycin is an antibiotic drug that belongs to the lincosamide family of drugs. It is widely used to treat infections, such as skin, urinary and respiratory infections, including sinusitis.
This medication is available in both oral and topical forms and works by inhibiting the growth of bacteria by blocking the production of proteins that bacteria need to survive.
Clindamycin has become a popular choice for treating sinusitis because of its efficacy and fewer side effects than other antibiotics.
Studies have shown that clindamycin is very effective in treating acute bacterial sinusitis after 10 days of treatment and usually does not require additional antibiotics.
It is also much less likely to cause an overgrowth of other bacteria or produce antibiotic resistance.
Although clindamycin is generally safe and well-tolerated, some people may experience side effects, such as nausea, vomiting, diarrhea, rash, and yeast infections.
In addition, in rare cases, it can cause a severe allergic reaction, so it is essential to talk to your healthcare professional before starting a course of treatment.
Clindamycin can also interact with certain medications, so it is important to tell your healthcare professional about any other drugs you are taking.
Can You Use Clindamycin For Sinus Infection?
Clindamycin is an antibiotic often prescribed to treat infections caused by bacteria, including sinusitis. It is in the class of medicines known as lincosamides, similar to penicillin but has a broader range of activity against certain infections caused by bacteria.
Clindamycin works by limiting the growth of bacteria and allowing the body’s immune system to fight off the infection.
This can help reduce the pain and discomfort associated with a sinus infection and clear up the condition more quickly.
Clindamycin has become increasingly popular in recent years due to its effectiveness in treating sinusitis.
Studies have found that it has a higher success rate than other antibiotics in curing sinusitis caused by certain bacteria. It is also effective in treating sinusitis resistant to other antibiotics.
In addition, it is generally a well-tolerated drug with few side effects, making it an attractive choice for treating sinusitis.
However, as with all antibiotics, it is essential to take the entire course of the drug as prescribed by your doctor and to make lifestyle changes to reduce the risk of future infection.
How good is clindamycin for sinus infection?
Clindamycin is generally considered a safe and effective acute sinusitis treatment if directed.
Additionally, it’s important to note that clindamycin has potential adverse effects, like with many antibiotics.
The most prevalent side effects include nausea, vomiting, and diarrhea, although severe side effects are rare.
It’s essential to speak to your doctor if you experience any of these side effects, as they may suggest an alternative treatment.
Overall, clindamycin is a safe and effective treatment option for chronic and acute sinusitis as long as it is prescribed.
Following your doctor’s instructions and taking the medication as directed can help reduce your symptoms and relieve chronic sinusitis pain.
How can clindamycin treat acute sinusitis?
Clindamycin is an antibiotic that is often prescribed to treat sinusitis. It works by stopping bacteria from multiplying, thereby reducing the duration and severity of the infection.
Clindamycin is especially effective against acute bacterial conditions caused by Streptococcus, commonly found in the sinuses.
However, it is essential to note that clindamycin does not work against viral infections, so you must seek other treatment options if you have a viral infection.
In conclusion, clindamycin is a popular antibiotic for treating acute and chronic sinusitis. It is generally well tolerated and effective in controlling infections caused by bacteria.
How long does it take for clindamycin to work?
Clindamycin is an antibiotic that is commonly used to treat sinusitis. It eliminates the bacteria that cause the infection.
However, depending on the severity of the infection, it can take several days to a few weeks for the full benefits of the antibiotic to be seen.
Therefore, taking the medication as prescribed is crucial to get optimal treatment and ensure the infection does not return.
In most cases, clindamycin will improve a person’s symptoms within a few days of starting the antibiotic.
However, it is crucial to understand that this does not necessarily imply the infection has been fully cleared.
Instead, it means that the antibiotic has begun to work and that the patient will likely experience some improvements in their symptoms. However, this is not a guarantee.
Therefore, it is essential to continue taking the medication until the entire course is finished to ensure the infection has been fully treated and reduce the chances of the infection returning.
Related: Clindamycin vs Doxycycline: Similarities, Differences, and Uses
What Conditions does clindamycin Treat?
Clindamycin is an antibiotic used to treat a variety of infections. It works by limiting the growth of bacteria, thus stopping the condition from worsening.
Clindamycin is commonly prescribed for sinusitis, both acute and chronic.
It effectively treats the infection-causing bacteria, usually Staphylococcus, Streptococcus, and Haemophilus species.
Clindamycin is also used to treat other bacterial infections, such as soft tissue and skin infections, sore throat, urinary and upper respiratory tract infections, and pneumonia. Additionally, clindamycin is also used to prevent infections caused by bacteria in people undergoing certain types of surgery or who have weakened immune systems.
While clindamycin is generally safe, speaking with a doctor and reporting any side effects that may occur when taking this medication is crucial.
Common side effects of clindamycin include nausea, vomiting, and upset stomach.
Overall, clindamycin is an effective antibiotic for infections caused by bacteria. However, speaking with a medical expert before taking any medication and reporting any side effects is crucial.
What Forms Does clindamycin Come In?
Clindamycin is available in multiple forms, including oral solutions, capsules, tablets, and topical creams.
The most common form of clindamycin for treating sinusitis is an oral solution taken thrice daily.
However, if sinusitis is more severe, a doctor may prescribe a higher clindamycin dosage or suggest a topical cream.
Additionally, before starting any antibiotic treatment, it is crucial to inform the doctor of any other medications being taken, as there may be interactions between the drugs.
Clindamycin is a solid and effective antibiotic that can treat sinus and other infections caused by bacteria. Still, it is crucial to be aware of the potential side effects.
Side Effects Of Clindamycin For Sinusitis
Clindamycin has been an antibiotic used to treat various infections, including sinusitis, for many years.
Clindamycin is generally safe and well-tolerated when taken correctly, but some potential side effects can occur.
These include:
- Nausea,
- Vomiting,
- Diarrhea,
- Abdominal pain
- Changes in appetite
In addition, in rare cases, patients may experience allergic reactions such as hives, difficulty breathing, and swelling of the face and throat.
Clindamycin can also cause a fall in the white blood cell count, escalating the risk of infection. Therefore, you must contact your doctor if you experience these symptoms while taking clindamycin.
It is important to remember that although clindamycin for sinus infection might be effective, it may not be the optimal option for everyone.
Some people may be more prone to side effects and should discuss the risks with their doctor before taking clindamycin.
It is also essential to take the medication exactly as prescribed and finish the entire course of treatment, even if symptoms improve.
This will ensure that the infection is completely eradicated and prevent a recurrence.
Read Also: Sinus Infection in Kids: Causes, Symptoms, Treatment & More
Dosage Of Clindamycin For Sinusitis
The recommended dosage of clindamycin for sinus infection differs from person to person.
It is typically prescribed as a capsule or oral solution and is usually taken twice to four times daily for 7 to 10 days.
However, it is essential to consult with a doctor for the exact dosage as it depends on how severe the infection is and the patient’s medical history. Your doctor might conduct a physical examination or sinus puncture to determine your condition accurately.
Clindamycin is an effective and widely used antibiotic for treating sinusitis.
However, it is essential to consult a doctor to prescribe the correct dosage for each individual.
Doing this allows the patient to get the most effective and safest treatment for their infection.
Frequently Asked Questions (FAQs)
Clindamycin User Reviews for Sinusitis
Save
Brand names:
Cleocin,
Cleocin Pediatric,
Cleocin Phosphate,
Cleocin HCl,
Cleocin Phosphate ADD-Vantage
Clindamycin
has an average rating of 6.6 out of 10 from a total of 29 reviews
for the
treatment of Sinusitis.
55% of reviewers reported a positive experience, while 31% reported a negative experience.
Filter by condition
All conditionsAspiration Pneumonia (1)BabesiosisBacteremia (2)Bacterial Endocarditis Prevention (5)Bacterial Infection (506)Bacterial Vaginosis (48)Bone infection (18)Deep Neck Infection (6)Diverticulitis (2)Intraabdominal Infection (2)Joint Infection (1)Lemierre’s SyndromeMalariaPelvic Inflammatory DiseasePeritonitis (11)Pneumocystis PneumoniaPneumonia (4)Prevention of Perinatal Group B Streptococcal Disease (1)Sinusitis (32)Skin or Soft Tissue Infection (105)Surgical Prophylaxis (34)ToxoplasmosisToxoplasmosis, Prophylaxis
Clindamycin rating summary
6.6/10 average rating
29 ratings from 32 user reviews.
Compare all 161 medications used in the treatment of Sinusitis.
10 | 41% | |
---|---|---|
9 | 7% | |
8 | 7% | |
7 | 7% | |
6 | 3% | |
5 | 0% | |
4 | 3% | |
3 | 3% | |
2 | 3% | |
1 | 24% |
Reviews for Clindamycin
Frequently asked questions
- What are the best antibiotics for a tooth infection?
- What is the best antibiotic to treat strep throat?
- Why can’t you lay down after taking clindamycin?
- Is clindamycin a strong antibiotic?
Are you taking this medicine?
- Add your review
- Learn more about Clindamycin
More FAQ
- Can I take clindamycin if I am allergic to penicillin?
- Is clindamycin a penicillin?
- Can clindamycin be used to treat chlamydia?
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.
Learn more about Sinusitis
- Common Side Effects from Antibiotics, and Allergies and Reactions
Care guides
- Sinusitis
Symptoms and treatments
- Acute Sinusitis
Medicine.com guides (external)
- Sinusitis Guide
More about clindamycin
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (791)
- Drug images
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: lincomycin derivatives
- Breastfeeding
- En español
Patient resources
- Drug Information
- Clindamycin (Intramuscular, Intravenous) (Advanced Reading)
- Clindamycin (Oral) (Advanced Reading)
- Clindamycin and sodium chloride (Advanced Reading)
- Clindamycin Capsules
Other brands
Cleocin, Cleocin Pediatric, Cleocin Phosphate, Cleocin HCl
Professional resources
- Prescribing Information
Related treatment guides
- Babesiosis
- Aspiration Pneumonia
- Bacteremia
- Bacterial Endocarditis Prevention
Treatment and prevention of acute sinusitis
In most cases, acute sinusitis does not require treatment, as it is caused by a viral infection (runny nose). As a rule, self-medication is sufficient for a speedy recovery and smoothing out the symptoms.
Treatment to relieve symptoms
Your doctor may recommend medication to relieve the symptoms of sinusitis. For example, drugs such as:
- Nasal saline spray to be injected into the nose several times a day to clear the nasal passages.
- Nasal corticosteroids. Corticosteroid nasal sprays can prevent or reduce inflammation. Examples of drugs: fluticasone (Flonase), mometasone (Nasonex), budesonide (Rinocort Aqua), triamcinolone (Nasacort AQ), beclomethasone (Beconase AQ).
- Decongestants. These preparations are available over the counter without a prescription and include drops, tablets, and nasal sprays. These drugs are used for several days, otherwise they can increase nasal congestion.
- Over-the-counter pain relievers include aspirin, acetaminophen (Tylenol and others) and ibuprofen (Advil, Motrin and others). Children should not be given aspirin.
Antibiotics
- Antibiotics are not usually needed to treat acute sinusitis.
- Antibiotics cannot treat acute sinusitis caused by a viral or fungal infection.
- Most cases of acute bacterial sinusitis can be treated without antibiotics.
- Antibiotics are generally used to treat severe, recurrent, or prolonged cases of bacterial infection.
- Antibiotics for acute sinusitis caused by a bacterial infection: amoxicillin, clarithromycin, etc. If the prescribed drug does not help against the infection, or the sinusitis recurs, the doctor may prescribe a different antibiotic.
- If your doctor has prescribed antibiotics for you, you need to complete the full course of treatment. This means that you need to take them for 10 to 14 days, even if the condition has already improved. If antibiotics are stopped early, symptoms may return.
Antifungals
In rare cases, acute sinusitis is caused by a fungal infection. Then intravenous drugs such as amphotericin B or voriconazole must be used. The dose of the drug, as well as how long you need to take it, depends on the severity of the infection and how quickly the symptoms of the disease are weakened.
Immunotherapy
If your sinusitis is accompanied by allergies, your doctor may prescribe allergen-specific immunotherapy, which will reduce your body’s response to allergens and help improve the condition.
Recommendations for home treatment
The following recommendations will help you weaken the symptoms of sinusitis:
- Observe the bed or home regimen. This will help your body fight infection and get better sooner.
- Drink plenty of fluids, such as water or juice. This will make the mucus thinner, which will help it drain. Avoid drinks containing caffeine or alcohol as they dehydrate the body. In addition, alcohol can worsen swollen sinuses and nose.
- Steam your nose. Breathe the steam over a bowl of hot water, covering your head with a towel, keeping your face directly above the steam. Or take a hot shower (if you don’t have a fever), breathing warm, moist air. This will help relieve pain and help the mucus pass.
- Apply warm compresses to the face. To relieve facial pain, cover your nose, cheeks, and eyes with a towel soaked in warm water.
- Flush nasal passages. Use a specially designed spray bottle (eg Sinus Rinse) to rinse your nasal passages.
- Sleep with your head elevated. This will help improve passage from the sinuses and reduce nasal congestion.
Prevention of acute sinusitis
th ways. Minimize contact with people who have a cold. Wash your hands frequently with soap, especially before eating.
You can get more detailed information about the treatment and prevention of acute sinusitis from the otolaryngologists of the Health 365 clinic in Yekaterinburg.
Otorhinolaryngology (ENT)
Otolaryngologist
ENT for children
ENT for patients over 70
Appointment with endoscopy
Diagnostics
Outpatient
Hospital operations
Diagnosis and treatment of acute sinusitis (sinusitis, frontal sinusitis, ethmoiditis , sphenoiditis) in Yekaterinburg in children and adults:
- st. Forge, 83
- st. Bazhova, 68
- st. Bazhova, 137
- st. Soyuznaya, 2
- st. Stepan Razin, 122
- st. Krestinsky, 2
Clinic “Health 365” – a network of multidisciplinary clinics of an expert class
Making an appointment with a doctor:
+7 (343) 270-17-17
Commercial and administrative issues:
+7 (343 ) 270-17 -20
E-mail:
[email protected]
list of the top 5 best and inexpensive drugs according to KP
Runny nose is one of the most common symptoms of many infectious and inflammatory diseases of the respiratory tract. In most cases, the cause of this disease is a respiratory virus that does not require special treatment. However, sometimes a runny nose can be a symptom of a serious illness caused by bacteria. Then the appointment of antibiotic therapy is a mandatory stage of treatment.
Sinusitis – inflammation of the mucous membrane of the maxillary paranasal sinus. Another name for the disease is maxillary sinusitis 1 . In 90-98% of cases, the cause of sinusitis are viruses. However, in 2-10% of cases, sinusitis is caused by bacteria that require antibiotic therapy.
Important! Selection of therapy should be carried out only by a doctor, taking into account symptoms, anamnesis, laboratory and instrumental data.
Consider the most effective and inexpensive antibiotics for adult sinusitis that are approved by practitioners and prescribed to patients.
List of top 5 antibiotics for sinusitis according to KP
Important! All drugs have side effects and contraindications. Our material is an overview and does not serve as a guide to action. Before buying drugs, consult your doctor.
Patients with sinusitis may be prescribed antibiotics from several pharmacological groups:
- penicillins;
- cephalosporins;
- macrolides;
- fluoroquinolones;
- lincosamides.
Penicillins
Penicillins are the main drugs of choice in the treatment of sinusitis. They are active against a wide range of pathogenic bacteria and can be prescribed from the first days of the disease even before the pathogen is identified. For the treatment of uncomplicated sinusitis, one of the representatives of this group is used – the beta-lactam antibiotic amoxicillin 1 . Perhaps the use of amoxicillin in combination with clavulanic acid, which enhances the effect of the antibiotic.
Contraindications for use: hypersensitivity, lymphocytic leukemia, infectious mononucleosis, severe gastrointestinal infections, allergic diathesis, bronchial asthma, hay fever.
Cephalosporins
II and III generation cephalosporins are used if the causative streptococcus is suspected to be resistant to beta-lactam antibiotics, particularly amoxicillin. Clinical guidelines of the Ministry of Health of the Russian Federation approved the use of cefuroxime, cefixime and cefditoren, which are prescribed in tablets and other forms for oral administration 1 .
Cephalosporins have a bactericidal effect: they contribute to the disruption of the synthesis of the bacterial cell wall, causing their death.
Contraindications for : Hypersensitivity to cephalosporins, penicillins and carbapenems.
Macrolides
Macrolides are alternative drugs for the treatment of sinusitis. They are used if the causative agent of the disease is resistant to beta-lactam antibiotics, or the patient is allergic to them.
Josamycin and clarithromycin in the form of tablets, capsules and other oral forms can be used in therapy. These antibiotics disrupt protein synthesis in the microbial cell, slow down or stop the growth of bacteria, and in high concentrations cause their death. Macrolides are considered one of the least toxic groups of antibiotics and are generally well tolerated.
Contraindications for the use of : hypersensitivity to macrolides, severe liver failure.
Fluoroquinolones
This group of antibiotics is prescribed in extreme cases and only for adult patients. The fact is that fluoroquinolones negatively affect the growing cartilaginous and connective tissue, therefore they are contraindicated in children and adolescents. Fluoroquinolones are recommended for severe sinusitis, for suspected polysinusitis, and for persistent structural changes in the nasal cavity.
Levofloxacin or monofloxacin tablets and other oral dosage forms may be used.
Contraindications for use : hypersensitivity to fluoroquinolones, pregnancy, lactation, age under 18 years, electrolyte disturbances, clinically significant bradycardia, heart failure, abnormal liver function.
Lincosamides
Clindamycin is an antibiotic from the lincosamide group that is active against a wide range of bacteria. Clindamycin disrupts protein synthesis in the bacterial cell, which slows down or completely stops its growth.
Clindamycin for sinusitis is prescribed for allergies to beta-lactam antibiotics and if there is a risk of anaerobic infection. In the latter case, a combination of clindamycin with third-generation cephalosporins can be used. Clindamycin preparations are used for intramuscular injection.
Contraindications for the use of : myasthenia gravis, ulcerative colitis, bronchial asthma, pregnancy, lactation, hypersensitivity to components.
How to choose antibiotics for sinusitis in adults
Independent choice of antibiotic therapy is not allowed! Treatment should be prescribed by a doctor individually, taking into account the clinical picture of the disease, the patient’s history, laboratory and instrumental data. The most important thing is to determine whether antibiotics are needed at all?
Let’s list the main symptoms that will make it possible to suspect a bacterial infection:
- symptoms (nasal congestion, headaches, general weakness) by 4-5 days do not weaken, but only intensify;
- body temperature does not drop below 37. 5 degrees;
- nasal discharge becomes yellow-green and copious;
- in the paranasal sinuses there is a feeling of fullness and pressure;
- soreness around nose and eyes.
The “gold standard” for diagnosing a bacterial infection is nasal culture and sensitivity to antibiotics. Only then can you be sure of the correctness of the prescribed therapy.
The main differences in antibacterial drugs lie in their mechanism of action.
Penicillins and cephalosporins inhibit the formation of proteins necessary for building the cell wall of the microorganism. Macrolides stop the growth and reproduction of bacterial cells. Fluoroquinolones interfere with DNA synthesis in the microbial cell.
Antibiotics are also divided into first-line, second-line and alternative drugs. The appointment of each group is carried out strictly according to indications. It is best to entrust the treatment to a specialist and avoid serious complications in the future!
Popular Questions and Answers
We discussed important issues related to the prescription of antibiotics for sinusitis with Tatiana Pomerantseva .