Effectiveness, Ease of Use, and Satisfaction

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Most voted positive review

58 People found this comment helpful

I have severe anxiety (Agorophbia) for 41 years from being druged at a party back in 1969, I’m now 58 years old. I’ve tried, hypnosis, books, head doctors, herbs, etc, don’t waste your time or money on these things for many years, like I did. This is a REAL ILLNESS contrary to what people tell you. The doctors will give you some paxel or celexa and send you home to get rid of you. Unless you have…

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Most voted negative review

10 People found this comment helpful

This is one of the most dangerous drugs in the world and I can’t understand how any doctor in good conscience could ever prescribe it for anyone. I am so sorry I ever took that first pill…I began having problems from the start but didn’t think it was the drug and the doctor didn’t seem to know what I was experiencing was coming from the drug either. I would get extremely lightheaded, so much…

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Shared reviews and ratings

SORT BY Condition: Tonic-Clonic Epilepsy

Overall rating 5.0

EffectivenessEase of UseSatisfaction

I’ve used this medication for anxiety disorders for over 20 years and it has saved my life and has never given me any problems. The negative comment person should have told her dr immediately and switched medications. It is a god send for 99% of us with anxiety or panic disorders. I would suggest it to everyone. I’ve been on it OVER 20 YEARS with no problems EVER

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Fill 3Created with Sketch. Condition: Panic Disorder

Overall rating 5.0

EffectivenessEase of UseSatisfaction

I’ve been on every benzo there is and I must say that klonopin has worked the best with little to no side effects. Second most effective was valium. I’m scripted 1mg 3Xs daily and 25% of the time I only need to take two tablets throughout the day. I have severe panic disorder and this medication has greatly improved my quality of life.

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Fill 3Created with Sketch. Condition: Panic Disorder

Overall rating 4.3

EffectivenessEase of UseSatisfaction

I just started taking this medicine yesterday. I have been on Xanax for years and in the past year I was diagnosed with panic disorder, ptsd, depression. I have been on so many medications that nothing has helped period. I have cried and prayed for something to give me relief. I have 2-4 panic attacks a day and atleast 3 times a week. My PCP finally gave me this medication and I can already tell it’s working as to where the Xanax worked for a few hours and here came another attack. The side affects I am learning and I do believe I have a few but man does it feel good not to be panicking every few hours and scared of the unknown. My attack have landed me at the ER several times and also always calling 911 cause of the unknowing of what is happening or afraid you’re dying of a heart attack or stroke when in reality it’s a sever panic attack. These are real and do t be afraid to seek help or get medication to help with them.. Read More Read Less

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Fill 3Created with Sketch. Condition: Panic Disorder

Overall rating 5.0

EffectivenessEase of UseSatisfaction

IF NOT FOR THIS LIL BEAUTY OF A PILL I WOULDNT BE ABLE TO EVEN LEAVE MY HOME. . I CAN DO WAY MORE NOW THEN BEFORE THIS PILL

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Fill 3Created with Sketch. Condition: Panic Disorder

Overall rating 2.3

EffectivenessEase of UseSatisfaction

Being on this pill longer than 6 years has ruined my breathing and sleep. I sleep good taking it but the sleep isn’t natural. It helps relax my muscles but slows down my brain too much and is not recommended for longer than 6 months and definitely not over 6 years like me. It messes up my muscles and it’s hard to relax and I’m restless sometimes. I gain some weight on it and I’m very tired during the day for 2-3 hours after I’m awake.

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Fill 3Created with Sketch. Condition: Other

Overall rating 1.0

EffectivenessEase of UseSatisfaction

After over a year on (doctor prescribed) Xanax 1/2 tablet 0. 5 mg at night for insomnia I went into Xanax withdrawal. I learned your brain gets use to benzos and eventually you will start withdrawal until you either take a higher dose or wean off. So basically you’re stuck in a very bad situation. The symptoms were excruciating. I spent seven nights in the hospital. They switched me to longer lasting Clonazepam and the next six months of my life was miserable, slowly withdrawing. Please don’t let this happen to you. Shame on drug makers and physicians for allowing withdrawal to happen to so many unsuspecting people. Read More Read Less

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Fill 3Created with Sketch. Condition: Panic Disorder

Overall rating 3.3

EffectivenessEase of UseSatisfaction

Very good at eliminating anxiety but after a year of use anxiety creeps back in..just worse. Increased anger was the main issue on this drug. Did and said things I’ll always regret. Got off the drug and have been so much better off.

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Overall rating 5.0

EffectivenessEase of UseSatisfaction

Changed my coping with serious breathing due to anxiety and panic attacks. Rather be addicted than having panic attacks

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Fill 3Created with Sketch. Condition: Panic Disorder

Overall rating 5.0

EffectivenessEase of UseSatisfaction

Amazing drug for anxiety, tried going off once didn’t turn out great, helps me till this day, I could not drive not even cut my hair getting a panic attack. am only on 0. 5 a day in the morning.
i recommend looking at the long term do you want to have a anxiety free life that helps you go through your day to day or do you want to live life like you have before taking this drug.
remember there is a reason why you tried this medication in the first place.
Everything is bad for you long term!
You just have to choose if you want to live in fear everyday or have atleast relieve until your time comes.
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Fill 3Created with Sketch. Condition: Panic Disorder

Overall rating 3.3

EffectivenessEase of UseSatisfaction

I’ve been taking drops, supposedly each drop has 0.1 mg of clonazepam, my psychiatrist started me on a too high dose (9 drops taken throughout the day with the highest dose before sleep
) I think for too long, since I’ve read mostly online that you are only supposed to take for weeks, and I’ve been on it for almost 4 months, currently taking 7 drops each day, next month will be 5 drops and so on till i hopefully will be off it in another 3 months.
I haven’t felt that many “depressive” side effects since I am also taking escitalopram, which I will be taking for at lest another 6 months.
A friend of mine told me she took it for only 8 weeks and then switched to another type of medicine which is not benzo, I wish I had known this before, now all I can do is wait patiently and taper slowly.Read More Read Less

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Fill 3Created with Sketch. Condition: Panic Disorder

Overall rating 5.0

EffectivenessEase of UseSatisfaction

I have been suffering from panic disorder for more than 6 years at first I had no idea what has happened to me later I consult with Dr. Than he prescribed me this med. And result was instant and so beneficial but it do have sideeffect on me if I just missed the doses I just felt it and it appear in work, regular work and daily life.

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Fill 3Created with Sketch. Condition: Seizures with Irregular Muscle Contractions

Overall rating 5.0

EffectivenessEase of UseSatisfaction

This medication helps me get through the hard days and I can leave it alone when I am feeling OK. Addiction comes with abuse. You can use this drug how it’s intended and be fine. It’s not intended for continuous long term use. I used it with the passing of my father and then 20yrs later while going through a nasty break up. I still have some left for when I need them. I have 3 refills and my next telehealth appt is in 5 months. I’m not sweating it. It’s all about Balance perception and accountability.Read More Read Less

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Fill 3Created with Sketch. Condition: Panic Disorder

Overall rating 5.0

EffectivenessEase of UseSatisfaction

I started this medication for anxiety. Not only did it work on my anxiety like nothing else had for 30 years of different treatments, it also brought to light that I was so anxious that I had lost my libido. I thought it was due to other factors but, once my anxiety was under control, my libido came back. I wish that doctors would understand that for some people, not all, the benefits outweigh the risks. I am able to take this as needed and not every day and it had changed my life 180 degrees. I believe that because I don’t take it every day, I’m not seeing the withdrawal or addiction issues. Nobody will prescribe it, even on an as needed basis. I finally found something that works after medication roulette for 30+ years and everyone is too scared of the opioid crisis to deal with people on a case by case basis. I really hate Healthcare and the way it is run.
They will pump me full of drugs with terrible side effects that I have to take everyday and say that they take months to work instead of this drug, which works within a hour and I don’t need everyday.Read More Read Less

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Fill 3Created with Sketch. Condition: A Feeling of Restlessness with Inability to Sit Still

Overall rating 5.0

EffectivenessEase of UseSatisfaction

Works very well at anxiety relief.

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Fill 3Created with Sketch. Condition: Panic Disorder

Overall rating 5.0

EffectivenessEase of UseSatisfaction

The only medication that stopped my panic attacks and constant state of terror. Therapy, xanax, antidepressants… Nothing worked.

1

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Overall rating 5.0

EffectivenessEase of UseSatisfaction

I have been taking this medication for years and it has helped me so much with my anxiety disorder, extreme depression and self esteem. It kept me stable and out of the hospital.

2

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Overall rating 5.0

EffectivenessEase of UseSatisfaction

It has been my saving grace. No side effects, not withdrawals. It is going to work if your responsible easy as that

2

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Fill 3Created with Sketch. Condition: Panic Disorder

Overall rating 4.3

EffectivenessEase of UseSatisfaction

I get cold sweats, heart palpolatios and nightmares, my brains goes into over time trying solve problems when I sleep. Clonazepam 1mg .75mg night + .25mg afternoon has reduced this episodes and let me sleep more peacefully some nights are still terrible. I am pretty much hooked now. I would hope I can get off it after 10 yrs.

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Overall rating 5.0

EffectivenessEase of UseSatisfaction

PTSD…severe. Taking this drug saved my life. I know it is habit forming, but better than the consequence of not taking it.

5

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Overall rating 3.0

EffectivenessEase of UseSatisfaction

Getting off this medication is pure hell. When getting on expect that you’re going to be on for a lifetime. Which is not really likely because it stops working. I gave five stars for effectiveness… Because it didn’t really work at some point. But one store for satisfaction because of the withdrawal. I’ve been off for about two months now and I’m starting to feel some relief

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Seizures (Generalized and Partial) Causes

Written by WebMD Editorial Contributors

• What Is a Seizure?
• Types of Seizures
• Seizure Symptoms
• Seizure Causes
• Seizure Diagnosis
• Seizure Treatment and Lifestyle Management
• More

A seizure is abnormal electrical activity in the brain that happens quickly. It may go nearly unnoticed. Or, in serious cases, it may cause unconsciousness and convulsions, when your body shakes uncontrollably.

Seizures usually come on suddenly. How long and serious they are can vary. A seizure can happen to you just once, or over and over. If they keep coming back, that’s epilepsy, or a seizure disorder. Less than 1 in 10 people who have a seizure get epilepsy.

Generalized seizures

Generalized seizures involve your entire brain from the start. Common subtypes include:

• Tonic-clonic. This is the most common subtype. Your arms and legs get stiff, and you may stop breathing for a bit. Then your limbs will jerk around. Your head will move about, as well.
• Absence seizures. You lose awareness briefly when you have one of these. Children get them more often than adults. Typically, they last only a few seconds.
• Febrile seizures. These are convulsions a child may have from a high fever caused by an infection. They can last a few minutes but are usually harmless.
• Infantile spasms. These usually stop by age 4. The child’s body gets stiff suddenly and their head goes forward. Many kids who have these get epilepsy later in life.

Focal seizures

There are two types:

• Focal onset aware seizure. You remain conscious during the seizure, which is very brief (usually less than 2 minutes). You may or may not be able to respond to people while it’s happening.
• Focal onset impaired awareness seizures can cause unconsciousness. You may also do things without knowing it, like lip smacking, chewing, moving your legs, or thrusting your pelvis.

Seizures can have different symptoms depending on the type of seizure, but may include: 

• Uncontrollable, spastic movements of your body, particularly your arms or legs
• Stiffening and then loosening of limbs or muscles
• Loss of consciousness
• Staring into space
• Confusion
• Sudden emotional states that can include a feeling of doom, deja vu, fear, or euphoria
• Sweating and nausea
• Involuntary movements of your tongue or mouth, screaming, or crying
• Rapid blinking
• Incontinence
• Falling

Seizures can happen with no explanation, but there are also conditions and events that can bring them on, including:

• Stroke
• Cancer
• Brain tumors
• Head injuries
• Electrolyte imbalance
• Very low blood sugar
• Repetitive sounds or flashing lights, as in video games
• Some medications, like antipsychotics and some asthma drugs
• Withdrawal or overdose from medications like benzodiazepines, narcotics, or alcohol
• Use of narcotics, such as cocaine and heroin
• Brain infections, like meningitis
• A high fever
• COVID-19
• Developmental brain abnormalities

Your doctor will ask for details about your seizure and do a neurological exam. This will include asking questions about your emotional state and testing your motor skills and mental functioning. Then they may order one or more of the following tests:

• Blood tests or a spinal tap to look for an infection
• Electroencephalography (EEG) during which a technician will attach electrodes to your scalp to monitor the electrical activity inside it
• An imaging test such as an MRI, CT, or PET scan to look for any problems in your brain 

If your seizures are happening frequently, your doctor may give you a more involved test in which electrodes are inserted into your brain through small holes in your skull. 

It’s possible to have only one seizure and not require treatment, but if your seizures continue, there are several ways your doctor may suggest treating them, including:

• Medication. Anti-seizure medications can cause some serious side effects, so you and your doctor will consider all the options and may need to try a few before you find one that’s effective and least likely to cause side effects.  
• Surgery. If your seizures always come from the same place in your brain, it may be possible for a neurosurgeon to remove just that portion of your brain to stop the seizures. 
• Vagus nerve stimulation. Your vagus nerve is the longest nerve in your skull, running all the way from your brain to your stomach. A specialist can implant a medical device under the skin of your chest that will send electrical signals along your vagus nerve to your brain and limit seizures. Usually, you still need to take medication. 
• Responsive nerve stimulation. A device implanted into your brain spots and then stops seizures. 
• Deep brain stimulation. Surgeons put devices into certain brain areas and then implant a pacemaker-like machine in your chest. It can send electrodes to those regions to prevent or stop seizure activity. 

What you can do to help with seizures

• Talk to your doctor about following a ketogenic diet, which is high in fat and protein and very low in carbohydrates. It has been shown to be helpful with reducing how often you have seizures.
• Get good sleep. Lack of sleep can be a trigger for seizures.
• Take any medications as directed. 
• Limit alcohol consumption.
• Pay attention to what things trigger your seizures and try to avoid them. 
• Wear a seizure alert device that can alert your caretakers when you are having a seizure. It does not prevent seizures from happening, but it can allow you to have more freedom and less worry.

Top Picks

Arpimed

Like all medicines, clonazepam can cause side effects, although not everyone gets them.

Important side effects:

Allergic reactions .

If you develop an allergic reaction, call your doctor immediately . Allergic reactions may manifest as the following symptoms:

• Sudden swelling of the larynx, face, lips and mouth. These symptoms can lead to difficulty breathing or swallowing.
• Sudden swelling of hands, feet and ankles.
• Skin rash or itching.

Cardiovascular adverse reactions

If you experience any of these symptoms, you should call your doctor immediately.

These symptoms include:

• Shortness of breath, swelling of the ankles, cough, fatigue and palpitations.
• Pain in the chest, which may radiate to the neck, shoulder and left arm.

Nervous system side effects

If you have any of these symptoms, you should talk to your doctor. These symptoms include:

• Feelings of aggression, agitation, irritability, nervousness, agitation, anxiety and hostility.
• Sleep disturbance, nightmares and vivid dreams.
• Hallucinations, manias and speech disorder.
• Development of new types of seizures not previously observed

Children and infants

• Special care should be taken when administering clonazepam to children and infants, as clonazepam may cause airway dysfunction, coughing and a feeling of choking. This may be caused by excessive salivation.
• Early puberty possible. After the abolition of clonazepam, this process stops.

Other possible side effects

Taking clonazepam may cause the following symptoms:

• Drowsiness and fatigue
• Dizziness and fatigue.
• Muscle weakness or flexibility, jerky movements (poor coordination)
• Walking instability

Tell your doctor if you have any of these symptoms. Your doctor will prescribe you a low dose, if necessary, by gradually increasing the dose of clonazepam.

The following symptoms may appear at any time during treatment with clonazepam

Mental activity and nervous system

• Impaired concentration, confusion and feeling lost (disorientation)
• Anxiety
• Difficulty in remembering new things
• Headache
• Depression
• Slow or broken speech
• Poor motor coordination, including unsteadiness when walking
• Increased incidence of epileptic seizures

Circulatory, renal and hepatic system

• Liver dysfunction (diagnosed by laboratory liver tests)
• Uncontrolled urination
• Problems with the circulatory system. Symptoms include feeling tired, bruising from minor concussions, shortness of breath, and nosebleeds.

Your healthcare provider should perform periodic blood tests if necessary.

Gastrointestinal tract

• Nausea
• Gastric disorders

Organs of vision

• Diplopia (double vision)
• Involuntary oscillatory movements (nystagmus)

Respiratory system

• Respiratory failure (respiratory depression). The first signs include sudden noisy, labored and irregular breathing. The development of cyanosis of the skin is possible.

Skin and hair

• Skin rash, urticaria and pruritus.
• Skin discoloration
• Hair loss

Reproductive system

• Decreased libido
• Erectile dysfunction

Withdrawal

When taking benzodiazepines such as clonazepam, addiction to the drug may develop. Therefore, with a sudden discontinuation or dose reduction of clonazepam, a withdrawal syndrome may develop.

Withdrawal may lead to the following symptoms:

• Sleep disturbance
• Muscle pain, tremor and restlessness
• Feelings of increased anxiety, tension, feelings of irritability or agitation, or changes in mood
• Increased sweating
• Headache

The following symptoms are less common:

• Hypersensitivity to light, noise and physical contact
• Hallucinations
• Tingling and numbness of hands and feet
• Feeling out of touch with reality

Trauma

Patients taking benzodiazepines are at an excessive risk of falling or breaking bones, especially the elderly, patients taking sedatives, including alcohol.

Reporting side effects

If you notice any side effects, tell your doctor, pharmacist or pharmacist, including any side effects not listed in this package insert. You can also report side effects to Arpimed LLC by going to the website www.arpimed.com and filling out the appropriate form “Report a side effect or ineffectiveness of a drug” and to the Scientific Center for Expertise of Drugs and Medical Technologies named after. Academician E.Gabrielyan, by going to the website www.pharm.am in the section “Report a side effect of a drug” and fill out the form “Map of reporting a side effect of a drug”. Scientific center hotline: +37410200505; +37496220505.

instructions for use, price, analogues, composition, indications

Tell the doctor about all currently or recently used medicines, as well as those that the patient plans to use. Clonazepam, taken concomitantly with other drugs, may change their effect, while other drugs may affect its effect.

The inhibitory effect of clonazepam on the central nervous system is enhanced by opium painkillers, drugs for general anesthesia (anesthetics), psychotropic drugs, antidepressants, antihistamines, drugs that reduce blood pressure of central action.

Disulfiram, cimetidine, erythromycin, ketoconazole, ritonavir, being inhibitors of cytochrome P-450 isoenzymes, inhibit the processes of biotransformation of 1,4-benzodiazepine derivatives and enhance their inhibitory effect on the central nervous system.

Drugs that induce the activity of cytochrome P-450 (for example, rifampicin, phenobarbital, phenytoin, primidone, carbamazepine) affect the processes of biotransformation of 1,4-benzodiazepine derivatives and lead to a weakening of their pharmacological action.

The use of alcohol during treatment with clonazepam enhances the inhibitory effect on the central nervous system and can lead to the development of paradoxical reactions, such as psychomotor agitation, aggressive behavior. In addition, alcohol enhances the sedative effect of clonazepam up to impaired coordination of movements and loss of consciousness.

Clonazepam, taken together with skeletal muscle relaxants, prolongs and potentiates the action of the latter.

Co-administration of clonazepam with the class III antiarrhythmic drug amiodarone may increase the toxicity typical of benzodiazepines (eg, central depression, motor coordination disorder).

Clonazepam, used simultaneously with other anticonvulsants, especially hydantoin or phenobarbital, may cause an increase in side effects associated with depression of the functions of the central nervous system.

Clonazepam, used simultaneously with sodium valproate, can induce epileptic seizures in the form of absences.

Tobacco smoking may reduce the effect of clonazepam.

Method of administration and dosage

Clonazepam should always be used as directed by a physician.

In case of doubt, a doctor should be consulted.

The doctor will determine the dose and duration of treatment individually for each patient.

Adults

The initial daily dose should not exceed 1.5 mg. Clonazepam should be used in doses divided into 3 divided doses at regular intervals. The dose should be increased gradually by 0.5-1 mg every 3 days, depending on the patient’s response to the drug, until a maintenance dose is reached, usually 4 mg to 8 mg per day.

The maximum maintenance daily dose, which should be achieved within 2-4 weeks of treatment, should not exceed 20 mg.

The simultaneous use of several antiepileptic drugs can lead to an increase in their inhibitory effect. This should be taken into account before the inclusion of Clonazepam in the treatment regimen with other antiepileptic drugs.

Children

Due to possible negative effects on physical or mental development after years of use, the benefits and risks of long-term use of clonazepam in children treated for epilepsy should be considered.

The initial dose in children aged 6 to 16 years is 0.5 mg / day.

Maintenance dose: 2-4 mg/day.

The daily dose should be divided into 3 or 4 parts and applied at regular intervals.

Patients with impaired renal and/or liver function

Caution should be exercised when using clonazepam in patients with impaired renal and hepatic function. It may be necessary to reduce the dose of the drug.

Elderly patients

Elderly patients are more sensitive to drugs that act on the central nervous system. It is recommended that the initial dose for these patients should not exceed 0.5 mg per day.

Mode of application

Clonazepam tablets should be taken orally with a small amount of water. The doctor will start treatment with the lowest effective dose and, if necessary, will gradually increase it.

If the use of the drug in equal doses is not possible, a larger dose should be taken at bedtime.

After reaching an effective maintenance dose, the drug can be used in a single daily dose at bedtime.

Duration of treatment

No data are available regarding the duration of treatment with Clonazepam. The doctor who prescribes long-term treatment with Clonazepam should periodically monitor the effectiveness of treatment in each patient individually. The duration of treatment is determined by the doctor, depending on the patient’s condition.

You can not abruptly stop taking the drug, it is always necessary to gradually reduce the dose under the supervision of a physician.

The dose should be reduced gradually by 0.125 mg 2 times a day every 3 days until the drug is completely discontinued.

If during treatment the patient feels that the effect of the drug is too strong or weak , he should consult a doctor.

In case of using Clonazepam at a dose of greater than prescribed

Symptoms

As a result of an overdose of clonazepam, the following symptoms may appear: drowsiness, a state of disorientation, slurred speech, and in severe cases, loss of consciousness, coma. Life-threatening poisoning can be caused by the simultaneous use of clonazepam and alcohol, or clonazepam and other drugs that have a depressant effect on the central nervous system.

If you use Clonazepam in a dose greater than prescribed, you should immediately contact your doctor or the nearest hospital emergency department. You should take the drug in the original packaging with you so that the staff can carefully check which drug has been used.

Measures taken

In case of poisoning with clonazepam, measures are aimed at the rapid elimination of the still unabsorbed drug from the body or a decrease in its absorption from the digestive tract. Airway patency, pulse, blood pressure should be monitored, and, if necessary, depending on the patient’s condition, appropriate symptomatic treatment should be carried out. The specific antidote is flumazenil.

In the event of missing a dose of the drug Clonazepam

If the patient forgets to take a dose of the drug, he should take the next dose as soon as possible, as soon as he remembers. However, if the time for the next dose is already approaching, you should skip the forgotten dose and take the next one as is. as scheduled. If the patient forgets to take two or more doses, you should consult a doctor.

Do not take a double dose to make up for a missed one.

Interruption of treatment with Clonazepam

You should not interrupt treatment with the drug, unless prescribed by a doctor. Possible recurrence of symptoms of the disease. If the doctor decides that it is necessary to stop using the drug, its dose should be reduced gradually over several days.

Abrupt discontinuation of clonazepam may cause a withdrawal syndrome (see section “Cautions Concerning Use”). Especially dangerous is the abrupt cessation of treatment carried out for a long time, or treatment requiring high doses of the drug. Withdrawal symptoms are then more pronounced. The doctor will determine the gradual withdrawal of the drug individually for each patient.

Side effects

The frequency and severity of side effects depends on the individual sensitivity of the patient and the dose of the drug taken.

Discontinuation of Clonazepam due to side effects is rare.

Blood and lymphatic system disorders: violations of the morphological composition of the blood.

Hypersensitivity reactions:

Immune system disorders: Anaphylactic reactions, vasomotor edema are described very rarely.

Skin and subcutaneous tissue disorders: allergic skin reactions (rash, itching, urticaria).

Metabolic and nutritional disorders: lack of appetite.

mental disorder

Paradoxical reactions – psychomotor anxiety, insomnia, agitation and aggressiveness, irritability, hostility, sleep disturbances, nightmares, personality disorders, muscle tremors, convulsions (new types).

Paradoxical reactions are most often observed after alcohol consumption, in elderly patients and in patients with mental illness.

Physical and psychological dependence may develop during treatment with clonazepam at therapeutic doses. The risk of developing dependence increases as the dose and duration of treatment increase. Patients with a history of alcoholism or other types of addiction are especially predisposed to developing addiction. Abrupt discontinuation of treatment may cause a withdrawal syndrome.

Pre-existing undiagnosed depression may occur during treatment with clonazepam.

Nervous system disorders: drowsiness, slow reaction, headache and dizziness, increased sensitivity to light, confusion and disorientation, ataxia. These effects are most often observed at the beginning of treatment, in elderly patients and, as a rule, disappear during ongoing therapy. In the event of an increase in these reactions, a corresponding dose reduction usually reduces their severity and frequency.

Sometimes, as well as after taking other benzodiazepines, especially in large doses, dysarthria with slurred speech and incorrect pronunciation, memory impairment may develop.

On the part of the organ of vision: visual impairment (blurred vision, diplopia, nystagmus).

Cardiac disorders: bradycardia, chest pain.

Vascular disorders: slight decrease in blood pressure.

Respiratory, thoracic and mediastinal disorders: rarely, respiratory center depression may develop especially when used simultaneously with other drugs that have a depressant effect on the respiratory center. In infants and children, especially if there are mental disorders, clonazepam may increase the production of bronchial secretions and saliva. In such cases, it is recommended to control the airway more often.

Gastrointestinal disorders: nausea, dyspepsia, dry mouth, unpleasant taste are rare.

From the side of the liver and biliary tract: a slight increase in aminotransferase activity, abnormal liver function, accompanied by jaundice.

Skin and subcutaneous tissue disorders: urticaria, rash, hair loss, pigmentation disorders.