What are the primary uses of Larpose 2 MG Tablet. How does lorazepam work in the body. What are the most common side effects of Larpose. Is Larpose safe during pregnancy and breastfeeding. How does Larpose interact with other medications.

Understanding Larpose 2 MG Tablet: Composition and Mechanism of Action

Larpose 2 MG Tablet is a medication containing lorazepam, a benzodiazepine class drug. This pharmaceutical agent operates by influencing the central nervous system, specifically targeting neurotransmitters in the brain. But how exactly does it work?

Lorazepam, the active ingredient in Larpose, binds to gamma-aminobutyric acid (GABA) receptors in the brain. This binding action enhances the inhibitory effects of GABA, a neurotransmitter responsible for reducing neuronal excitability. The result? A calming effect on the brain and nervous system, leading to sedation and anxiety reduction.

The Science Behind Lorazepam’s Action

When lorazepam attaches to GABA receptors, it increases the neuron’s sensitivity to chloride ions. This heightened sensitivity causes hyperpolarization of the neuronal membrane, effectively stabilizing it and reducing its excitability. This mechanism underlies the anxiolytic, sedative, and anticonvulsant properties of Larpose.

Primary Uses of Larpose 2 MG Tablet: From Anxiety to Epilepsy

Larpose 2 MG Tablet has a wide range of therapeutic applications, making it a versatile medication in the field of psychiatry and neurology. What conditions does it treat?

• Insomnia
• Anxiety disorders
• Status epilepticus
• Panic attacks and disorders
• Pre-surgical anxiety
• Premenstrual syndrome
• Phobias
• Alcohol Withdrawal Syndrome

Its ability to induce calmness and reduce excessive brain activity makes it particularly useful in managing acute anxiety episodes and seizures. Additionally, its sedative properties contribute to its effectiveness in treating insomnia and pre-operative anxiety.

Side Effects of Larpose: What Patients Should Know

While Larpose can be highly effective in treating various conditions, it’s crucial to be aware of potential side effects. What are the most common adverse reactions associated with Larpose 2 MG Tablet?

• Sedation and drowsiness
• Dizziness and lightheadedness
• Headaches
• Difficulty concentrating
• Memory impairment
• Blurred vision
• Nausea and vomiting
• Low blood pressure
• Increased salivation
• Nasal congestion

It’s important to note that these side effects can vary in severity and frequency among individuals. Patients should report any persistent or severe side effects to their healthcare provider promptly.

Rare but Serious Side Effects

While less common, some patients may experience more severe side effects. These can include:

• Severe allergic reactions
• Paradoxical reactions (increased anxiety or agitation)
• Respiratory depression
• Suicidal thoughts

Immediate medical attention is necessary if any of these rare but serious side effects occur.

Contraindications and Precautions: When to Avoid Larpose

Not everyone can safely use Larpose 2 MG Tablet. Several conditions and factors may contraindicate its use. When should Larpose be avoided?

• Known allergy to lorazepam or other benzodiazepines
• Severe liver problems
• Respiratory depression
• Glaucoma
• Concurrent use with opioids
• Chronic alcoholism
• Sleep apnea
• Myasthenia gravis
• History of drug dependency or abuse
• Severe kidney disease
• Chronic Obstructive Pulmonary Disease (COPD)

Patients with any of these conditions should consult their healthcare provider before considering Larpose as a treatment option. Alternative medications or therapies may be more appropriate in these cases.

Larpose and Pregnancy: Understanding the Risks

The use of Larpose during pregnancy is a topic of significant concern. Is it safe to take Larpose while pregnant?

Medical professionals generally advise against using Larpose during pregnancy. It’s classified as a category D medication, indicating potential risks to the fetus. The active ingredient, lorazepam, contains teratogenic substances that could harm fetal development.

If a benzodiazepine is deemed necessary during pregnancy, healthcare providers may consider alternative medications with a better safety profile. It’s crucial for pregnant women to consult with their obstetrician or gynecologist before starting or continuing any benzodiazepine treatment.

Larpose and Breastfeeding

Similar concerns exist regarding the use of Larpose during breastfeeding. Can nursing mothers safely take Larpose?

Lorazepam is known to be excreted in breast milk, potentially causing withdrawal symptoms in infants. For this reason, Larpose is not recommended for use by breastfeeding mothers. If a benzodiazepine is necessary, healthcare providers may suggest alternatives with lower risks to nursing infants.

As always, breastfeeding women should consult their healthcare provider before starting or continuing any medication, including Larpose.

Interactions with Other Medications: What to Watch Out For

Larpose can interact with various other medications, potentially altering its effectiveness or increasing the risk of side effects. What are some key drug interactions to be aware of?

• Opioids (e.g., fentanyl, morphine): Can increase the risk of severe sedation and respiratory depression
• Alcohol: May enhance sedative effects and increase the risk of respiratory depression
• Other CNS depressants: Can potentiate the sedative effects of Larpose
• Certain antidepressants: May alter the metabolism of lorazepam
• Antipsychotics: Can increase the risk of sedation and cognitive impairment

It’s crucial for patients to inform their healthcare provider about all medications, including over-the-counter drugs and herbal supplements, they are taking before starting Larpose.

Larpose and Alcohol: A Dangerous Combination

The interaction between Larpose and alcohol deserves special attention. Why is this combination particularly risky?

Consuming alcohol while taking Larpose can lead to severe sedation, impaired cognition, and dangerous respiratory depression. In extreme cases, it may even result in coma. For these reasons, patients are strongly advised to avoid alcohol completely while using Larpose.

Proper Usage and Dosage Guidelines for Larpose 2 MG Tablet

Correct administration of Larpose is crucial for its safety and effectiveness. How should patients take this medication?

• Follow your physician’s instructions precisely
• Take the tablet orally, swallowing it whole
• Can be taken with or without food
• Do not crush, chew, or break the tablet
• For faster absorption, the tablet can be placed under the tongue (sublingual administration)
• Never share your medication with others

Dosage typically varies based on the condition being treated, the patient’s age, and other individual factors. Always adhere to the prescribed dosage and never adjust it without consulting your healthcare provider.

Special Considerations for Elderly Patients

Older adults may be more sensitive to the effects of Larpose. How does this affect dosing for elderly patients?

Healthcare providers often start elderly patients on lower doses of Larpose and adjust gradually as needed. This approach helps minimize the risk of side effects such as excessive sedation or falls. Close monitoring is essential in this population.

Long-term Use of Larpose: Benefits and Risks

While Larpose can be highly effective for short-term use, long-term administration requires careful consideration. What are the potential benefits and risks of prolonged Larpose use?

Benefits of long-term use may include sustained anxiety relief and improved quality of life for those with chronic anxiety disorders. However, extended use also carries risks, including:

• Development of tolerance, requiring higher doses for the same effect
• Physical dependence and withdrawal symptoms upon discontinuation
• Cognitive impairment, particularly in older adults
• Increased risk of falls and accidents

Healthcare providers carefully weigh these factors when considering long-term Larpose therapy. Regular reassessment of the need for continued treatment is crucial.

Tapering Off Larpose

If long-term use of Larpose is no longer necessary, how should patients discontinue the medication?

Abrupt discontinuation of Larpose can lead to withdrawal symptoms, including rebound anxiety and seizures. To avoid these effects, healthcare providers typically recommend a gradual tapering of the dose over several weeks or months. This process should always be supervised by a medical professional.

Alternatives to Larpose: Exploring Other Treatment Options

While Larpose can be effective for many patients, it’s not the only option for treating anxiety, insomnia, or seizures. What alternatives might healthcare providers consider?

• Other benzodiazepines with different durations of action
• Non-benzodiazepine anxiolytics (e.g., buspirone)
• Antidepressants with anxiolytic properties (e.g., SSRIs)
• Cognitive-behavioral therapy for anxiety and insomnia
• Mindfulness and relaxation techniques
• Alternative anticonvulsants for seizure disorders

The choice of treatment depends on various factors, including the specific condition, patient preferences, and potential side effects. A comprehensive discussion with a healthcare provider can help determine the most appropriate treatment approach.

Combining Larpose with Non-Pharmacological Therapies

In many cases, the most effective treatment approach combines medication like Larpose with non-pharmacological interventions. How can this combination therapy enhance outcomes?

Pairing Larpose with therapies such as cognitive-behavioral therapy (CBT) or relaxation techniques can provide more comprehensive management of anxiety or insomnia. This approach may allow for lower medication doses and potentially reduce the risk of dependence. Additionally, learning coping strategies through therapy can provide long-term benefits that extend beyond the duration of medication use.

Monitoring and Follow-up: Ensuring Safe and Effective Treatment with Larpose

Regular monitoring is crucial for patients taking Larpose, especially those on long-term therapy. What should this monitoring entail?

• Regular check-ups to assess the medication’s effectiveness
• Monitoring for side effects and adjusting dosage if necessary
• Periodic liver and kidney function tests
• Assessment of cognitive function, particularly in older adults
• Evaluation of the ongoing need for treatment

Healthcare providers may also recommend periodic “drug holidays” to assess the continued need for Larpose and to minimize the risk of dependence.

Patient Education and Empowerment

Effective use of Larpose relies heavily on patient understanding and engagement. How can healthcare providers ensure patients are well-informed about their treatment?

Comprehensive patient education should cover:
– Proper usage and dosing instructions
– Potential side effects and when to seek medical attention
– Risks of drug interactions, particularly with alcohol
– Signs of dependence or tolerance
– The importance of not abruptly discontinuing the medication

Empowering patients with this knowledge enhances treatment adherence and safety.

Future Directions in Anxiety and Seizure Management: Beyond Larpose

As medical research advances, new treatment options for anxiety disorders and seizures continue to emerge. What future developments might impact the use of medications like Larpose?

Ongoing research is exploring:
– Novel anxiolytic compounds with fewer side effects
– Targeted therapies based on individual genetic profiles
– Advanced brain stimulation techniques for anxiety and seizure management
– Refinement of existing medications to reduce side effects and dependence potential

These advancements may eventually provide alternatives to traditional benzodiazepines like Larpose, offering more personalized and potentially safer treatment options.

The Role of Telemedicine in Anxiety Management

The rise of telemedicine has implications for the management of conditions typically treated with Larpose. How might remote healthcare delivery impact anxiety treatment?

Telemedicine offers potential benefits such as:
– Improved access to mental health professionals
– More frequent check-ins and medication adjustments
– Integration of digital tools for anxiety management
– Enhanced monitoring of medication effects and side effects

However, it also presents challenges, particularly in initial assessment and ongoing monitoring of medications like Larpose. Striking a balance between convenience and comprehensive care remains a key consideration in the evolving landscape of anxiety treatment.

Larpose 2 MG Tablet (10): Uses, Side Effects, Price & Dosage

HomeLarpose 2mg Tablet

By CIPLA LIMITED

10 Tablet(s) in Strip

All the Products are packed and stored Safely

Larpose 2 MG Description

Larpose Tablet contains an active ingredient called lorazepam which belongs to a class of medications known as benzodiazepines. This medicine acts on the brain and nerves (central nervous system). It

is an intermediate-acting tranquilliser that interferes with the natural state of certain neurotransmitters called gamma-aminobutyric (GABA). Lorazepam binds to these GABA receptors and enhances the GABA enhanced synaptic inhibition, responsible for its calmness and sedation effects.

Product Summary

Check more medicines with composition as Lorazepam(2. 0 Mg)

Uses of Larpose 2 MG

• Insomnia

• Anxiety disorders

• Status epilepticus

• Panic attacks and disorders

• Before surgery

• Premenstrual syndrome

• Phobias

• Alcohol Withdrawal Syndrome

Contraindications of Larpose 2 MG

If you are allergic to lorazepam
If you have liver problems
If you have respiratory depression
If you have glaucoma (optic nerve damage)
If you are using it with opioids
If you are a chronic alcoholic
If you have sleep apnoea
If you have chronic respiratory illness
If you have myasthenia gravis (neuromuscular disease)
If you have medicine dependency or medicine abuse
If you have kidney disease
If you have Chronic Obstructive Pulmonary Disease (COPD)…

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Side effects of Larpose 2 MG

• Sedation

• Drowsiness

• Headaches

• Dizziness

• Lightheadedness

• Irritability

• Difficulty concentration

• Memory loss

• Impaired judgement

• Constipation

• Depression

• Blurred vision

• Talkativeness

• Nausea

• Vomiting

• Low blood pressure

• Increased salivation

• Nasal congestion

Precautions and Warnings of Larpose 2 MG

Pregnancy

Q:

Can I take Larpose Tablet during pregnancy?

A:

No, avoid taking Larpose Tablet during pregnancy since it is a category D medicine. There are certain teratogenic or foetus-harming substances in the medicine. Therefore the use of this medicine during pregnancy is not recommended. If a benzodiazepine is required, a medicine other than Larpose can be preferred. Consult a doctor or a gynaecologist before starting any benzodiazepine during pregnancy. Never self prescribe, or self medicate.

Breast Feeding

Q:

Can I take Larpose Tablet while breastfeeding?

A:

No, Larpose Tablet is not recommended during breastfeeding as lorazepam is secreted in breast milk. It may cause withdrawal symptoms in the baby. If a benzodiazepine is required, a medicine other than Larpose can be preferred. Consult a doctor or a gynaecologist before starting any benzodiazepine during pregnancy. Never self prescribe, or self medicate.

Driving

Q:

Can I drive if I have taken Larpose Tablet?

A:

Avoid driving if you have taken tablet Larpose Tablet as it will cause sedation, drowsiness, dizziness, impaired judgement, and fainting.

Alcohol

Q:

Can I consume alcohol with Larpose Tablet?

A:

No, avoid consuming alcohol while taking Larpose Tablet as it will cause sedation, drowsiness, respiratory depression, slow and shallow breathing. Serious drinking of alcohol while taking Larpose Tablet may result in a coma.

Other General Warnings

Talk to your doctor if

• You are allergic to lorazepam.

• You have liver disease.

• You have kidney disease.

• You have a history of medicine abuse or dependence.

• You are a chronic alcoholic.

• You have sleep apnea.

• You have lung issues like Chronic Obstructive Pulmonary Disease (COPD).

• You have depression.

• You have narrow-angle glaucoma.

Mode of Action of Larpose 2 MG

How Does It Work?

Lorazepam is a benzodiazepine that binds itself to a Gamma-aminobutyric (GABA) receptor present in the postsynaptic neuron and enhances its inhibitory action. The increased neuronal excitability to chloride ions results in hyperpolarisation of the neuronal membrane and results in stabilisation….

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Directions for Use of Larpose 2 MG

• Take medicine as directed by your physician.

• You can take Larpose Tablet with or without food.

• Take the tablet orally and swallow it whole.

• Do not crush, chew, or break the pill.

• Do not share your medicine with anyone.

• You can also take the tablet sublingually by keeping it below your tongue for faster disintegration.

Interactions of Larpose 2 MG

Interactions with other medicines

• Opioids like fentanyl, morphine, codeine

• CYP3A4 Inhibitors like Ketoconazole, Clarithromycin, Itraconazole, Erythromycin, Ritonavir, Verapamil, Diltiazem

• SSRIs like sertraline, fluoxetine, etc.

• TCA like imipramine

• Antipsychotics like risperidone, clozapine

• Antihistamines and muscle relaxants

Interactions with food items

Storage and disposal of Larpose 2 MG

Store Larpose in a dry, cool place away from heat and humidity. Keep the tablets in the same packing as they came. Keep them out of reach of children and pets. The pills that are not needed anymore should be safely disposed of to avoid accidental usage. They should not be flushed in the toilet….

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Dosage of Larpose 2 MG

Overdose

• Overdose of Larpose Tablet can result in drowsiness, respiratory depression, slowed breathing, sedation, anxiety, depression, panic attacks, insomnia, headache, sweating, delirium, slurred speech, coma, muscle fatigue, ataxia, feeling lightheaded, fainting, and shallow breath. Consult your physician in case of an overdose or rush to emergency medical services….

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Missed a Dose

If one misses a dose, one should take the missed dose as soon as one remembers. If it’s time for the next dose, one should continue with the regular dosage. Do not take a double dose to compensate for the missed dose….

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Frequently Asked Questions (FAQs)

Q: How much time does it take for Larpose Tablet to start showing its effect?

A: It takes around 30 mins to 1 hour for Larpose Tablet or lorazepam to show its effect clinically when taken orally. The onset of action is even faster if lorazepam is taken through the intravenous or intramuscular route. It has a total duration of action of around 11-20 hours.

Q: Can I take Larpose Tablet if I have kidney disease?

• Lorazepam: Worsening of delirium: 3 case reports. React Wkly [Internet]. 2017 [cited 2022 Jan 24];1633(1):468–468.
• Lorazepam (ativan). Med Lett Drugs Ther [Internet]. 1978 [cited 2022 Jan 24];20(6):31–2.
• Lorazepam 2.5mg Tablets [Internet]. Org.uk. [cited 2022 Jan 24].

Product Details

Brand

LARPOSE

Expires on or After

02/10/2023

• LARPOSE 1MG TABLET

Last Updated on: 02 Feb 2022 | 10:57 AM (IST)

Disclaimer

The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner’s medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.

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Larpose 2mg Tablet: View Uses, Side Effects, Price and Substitutes

Product introduction

Larpose 2mg Tablet is a prescription medicine used to treat symptoms of short term anxiety and anxiety disorders. It helps to decrease the abnormal and excessive activity of the nerve cells and calms the brain.

Larpose 2mg Tablet is taken by mouth with or without food. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor as it has a high potential of habit-forming. If you have missed a dose, take it as soon as you remember it and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor as it may increase seizure frequency.

Some common side effects of this medicine include fatigue and balance disorder. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.

Uses of Larpose Tablet

• Treatment of Short term anxiety
• Treatment of Anxiety disorder

Benefits of Larpose Tablet

In Treatment of Short term anxiety

Larpose 2mg Tablet reduces the symptoms of excessive anxiety and worry that may arise in stressful conditions such as an exam or job interview. It can also reduce feelings of restlessness, tiredness, difficulty concentrating and feeling irritable. This will therefore help you go about your daily activities more easily and be more productive. Keep taking this medicine even if you feel well. Stopping suddenly can cause serious problems.

In Treatment of Anxiety disorder

Larpose 2mg Tablet helps relieve symptoms of many anxiety disorders including obsessive-compulsive disorder and generalised anxiety disorder by increasing the level of a chemical called GABA in your brain. This prevents abnormal symptoms of anxiety such as restlessness, tiredness, difficulty concentrating, feeling irritable and sleep problems. It helps you feel calm with a better ability to deal with problems. Exercise and a healthy diet can also improve your mood. Keep taking the medicine until your doctor advises you to stop.

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Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Larpose

• Dizziness
• Sedation
• Injection site pain
• Fatigue
• Muscle weakness
• Drowsiness

How to use Larpose Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Larpose 2mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Larpose Tablet works

Larpose 2mg Tablet is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Larpose 2mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Larpose 2mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Larpose 2mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Larpose 2mg Tablet should be used for short periods and sleepiness of the baby should be watched. The withdrawal of Larpose 2mg Tablet should be gradual.

Driving

UNSAFE

Larpose 2mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Larpose 2mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Larpose 2mg Tablet may be needed. Please consult your doctor.
However, inform your doctor if you have any underlying kidney disease.

Liver

CAUTION

Larpose 2mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Larpose 2mg Tablet may be needed. Please consult your doctor.
Use of Larpose 2mg Tablet is not recommended in patients with severe liver disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

No substitutes found for this medicine

Quick tips

• The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor
• It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
• Avoid consuming alcohol as it may increase dizziness and drowsiness.

• Inform your doctor if you are pregnant, planning to conceive or breastfeeding.

• Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremor, and confusion.

Fact Box

Chemical Class

Benzodiazepines Derivative

Habit Forming

Yes

Therapeutic Class

NEURO CNS

Action Class

Benzodiazepines

Interaction with drugs

Taking Larpose with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Abacavir

Brand(s): Abamune, A-Bec, Virol

Serious

Adefovir

Brand(s): Adesera, Adheb, Adfovir

Serious

Amisulpride

Brand(s): Stozen, Sulpigold, Amisulide

Serious

Amitriptyline

Brand(s): Triptam

Serious

View all interactions

Patient concerns

I feel short term memory loss , anxiety and mood disorder

Dr. Vikas Sharma

Neurology

Do Mri brain and thyroid testing

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I feel fear, anxiety, fast heart beat, ear tinitus Drowsy mind, No activeness, At present im taking liofen xl 20mg, and larpose 2mg, daily night

Dr. Jyoti Kapoor Madan

Psychiatry

Based in your clinical history, your doctor plans the type of medicine and it’s dose and duration. For first episode of anxiety/ depression/ panic, the usual maintenance phase is 6 months of asymptomatic period, after which medicines can be gradually tapered. But treatment may need to continue longer depending on severity and frequency of episodes. To take any decision to change medication or stop them, several factors have to be taken in account for which regular follow up with your psychiatrist is important. For second opinion, seek a proper consultation with another psychiatrist and take along your previous prescriptions.

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My mother she is taking tablets larpose 2mg & trinicalm plus since 20yrs. Both tablet were suggested by doctor at that time now the same tablets are very difficult to get in medical & also substitutes not available. Since that she is suffering from sleeping disorder.

Dr. Jyoti Kapoor Madan

Psychiatry

Sleeping pills are not recommended for more than few weeks, and if they are needed, regular follow up with psychiatrist are recommended. The psychiatrist will need to evaluate the reason for sleep issues and treat accordingly.

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i am suffering from anxiety disorder and i am on anxiety medications does ayurveda has any treatment for anxiety disorder

Dr. Aanchal Maheshwari

Ayurveda

Yes, Panchkarma is the best you should take sitting of sirodhara

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Mixed anxiety depressive disorder

Dr. Jyoti Kapoor Madan

Psychiatry

Depression is a persistent state of sadness that is the result of interaction between one’s inner biological and psychological state and gets triggered of with environmental stressors. Reactive depression is in response to a situation like loss, sickness, trauma etc. Endogenous depression occurs without any noticeable environmental stressors. Psychological symptoms include lack of interest, negative thinking, irritability, frustration, feeling demotivated etc. Somatic symptoms like fatigue/ weakness/ lack of sleep/ lack of appetite and other physical symptoms are common. Anxiety is common. In severe cases one may feel helpless and hopeless enough to wish for death or attempt suicide. Treatment includes physical and psychiatric work up following which medicines can be prescribed. In milder cases, psychotherapy or counselling is recommended.

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Generalized anxiety disorder problem

Dr. Jyoti Kapoor Madan

Psychiatry

Anxiety is the result of a hyperarousal state of nervous system due to a low threshold for threat perception. In simpler words, it’s an ongoing flight or fight response. It can elicit a neuro-hormonal response understood as Flight or Fright reaction kicking in physiological cascade of symptoms ranging from palpitations, tachycardia, breathlessness, increased bowel movement, increase frequency of urination, dizziness, muscle tension or pain, trembling, dizziness, blurring of vision to restlessness, confusion and fainting spells. Chronic stress causes prolonged anxiety response with the consequences of slowed me ration, lack of concentration, headaches, fluctuations in blood pressure and increased wear and tear of body tissues. Identifying your stressors, learning to deal with them, de stressing regularly by doing something that makes one feel good, yoga and meditation are some non pharmacological strategies to deal with it. If the condition is persisting for a long time, it’s better to see a psychiatrist.

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Mental Depression , Anxiety disorder

Dr. Jyoti Kapoor Madan

Psychiatry

Depression is a persistent state of sadness that is the result of interaction between one’s inner biological and psychological state and gets triggered of with environmental stressors. Reactive depression is in response to a situation like loss, sickness, trauma etc. Endogenous depression occurs without any noticeable environmental stressors. Psychological symptoms include lack of interest, negative thinking, irritability, frustration, feeling demotivated etc. Somatic symptoms like fatigue/ weakness/ lack of sleep/ lack of appetite and other physical symptoms are common. Anxiety is common. In severe cases one may feel helpless and hopeless enough to wish for death or attempt suicide. Treatment includes physical and psychiatric work up following which medicines can be prescribed. In milder cases, psychotherapy or counselling is recommended.

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User feedback

Patients taking Larpose 2mg Tablet

Once A Day

83%

Twice A Day

8%

Thrice A week

4%

Thrice A Day

3%

Alternate Day

2%

Four Times A *

1%

*Four Times A Day

What are you using Larpose Tablet for?

Short term an*

73%

Others

18%

Anxiety disor*

9%

*Short term anxiety, Anxiety disorder

How much was the improvement?

Average

44%

Excellent

39%

Poor

17%

What were the side-effects while using Larpose 2mg Tablet?

No Side Effec*

50%

Nail disorder

17%

Balance disor*

17%

Dizziness

17%

*No Side Effect, Balance disorder (loss of balance)

How do you take Larpose Tablet?

With food

67%

With or witho*

33%

*With or without food

Please rate Larpose 2mg Tablet on price

Average

56%

Expensive

22%

Not Expensive

22%

FAQs

Q.

Is Larpose 2mg Tablet an opioid? Is it a habit-forming medicine?

No, Larpose 2mg Tablet is not an opioid. It belongs to the benzodiazepine group of medicines and is used for short-term treatment (2-4 weeks) only. It is a habit-forming medicine and can make a person physically and psychologically dependent.

Q. Can Larpose 2mg Tablet be used as a sleeping pill?

Larpose 2mg Tablet is used for sleeping difficulties caused due to short-term anxiety. One of the very common side effects of Larpose 2mg Tablet is drowsiness and sleepiness. It calms the mind, and therefore, helps a person to sleep.

Q. For how long will Larpose 2mg Tablet stay in my system?

Larpose 2mg Tablet may take around 3 days to get completely removed from the system.

Q. Are there any symptoms that I would experience if I get addicted to Larpose 2mg Tablet?

The most important symptom of addiction is that you may feel unpleasant if you do not take Larpose 2mg Tablet. Another symptom could be that you may increase the dose on your own to feel its effect.

Q. If I suddenly stop taking Larpose 2mg Tablet, will it affect me adversely?

You should reduce the dose of Larpose 2mg Tablet gradually before completely stopping it. Suddenly stopping it may lead to withdrawal symptoms which include loss of the sense of reality, feeling detached from life, and unable to feel emotion. Some patients have also experienced numbness or tingling in the arms or legs, tinnitus (ringing sounds in the ears), uncontrolled or overactive movements, twitching, shaking, feeling sick, being sick, stomach upsets or stomach pain, loss of appetite, agitation and abnormally fast heart beats. It can also cause panic attacks, dizziness or feeling faint, memory loss, hallucinations, feeling stiff and unable to move easily, feeling very warm, convulsions (sudden uncontrolled shaking or jerking of the body) and oversensitivity to light, sound and touch.

Q. Does Larpose 2mg Tablet cause weight gain?

The effect of Larpose 2mg Tablet on weight gain or loss is not known.

Q. Does Larpose 2mg Tablet cause depression?

If you have a history of depression then it may increase the risk of developing depression again. Larpose 2mg Tablet should not be used alone in depressed patients because it may cause suicidal tendencies in such patients.

Q. My old uncle is taking Larpose 2mg Tablet for sleeplessness associated with anxiety. Can it affect his memory?

Though it is rare, but use of Larpose 2mg Tablet can cause memory impairment, which may be more apparent in old age patients.

Q. Are there any harmful effects of taking more than the recommended doses of Larpose 2mg Tablet?

Taking more than the recommended dose of Larpose 2mg Tablet may cause loss of muscle control, low blood pressure, mental confusion, slow breathing and even coma. If you have taken higher than the recommended dose of Larpose 2mg Tablet, seek immediate medical help immediately.

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Disclaimer:

Tata 1mg’s sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

1. Stahl SM, editor. Lorazepam. In: Stahl’s Essential Pschopharmacology: Prescriber’s Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 367-71.

2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 819-20.

3. Drugs.com. Lorazepam Pregnancy and Breastfeeding Warnings. [Accessed 25 Mar. 2019] (online) Available from:

4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:

5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:

Manufacturer

Name: Cipla Ltd

Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Country of origin: India

NOT FOR SALE

We do not facilitate sale of this product at present

Memorial Sloan Kettering Cancer Center

Adult Medication

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This document, provided by Lexicomp ^® , contains all the information you need to know about this medicine, including indications, directions for use, side effects, and when your healthcare provider should be contacted.

Trade names: USA

Cytomel; Triostat [DSC]

Trade names: Canada

Cytomel; TEVA-Liothyronine

Warning

• This drug should not be used to reduce body weight. Severe and sometimes deadly side effects can occur when this drug is taken in high doses or with certain other weight loss drugs. If you have any questions, please consult your doctor.

What is this drug used for?

• It is used as a substitute for thyroid hormone.
• Used to treat thyroid cancer.
• Used to diagnose thyroid problems.
• This drug may also be used for other indications. Consult your doctor.

What should I tell my doctor BEFORE taking this drug?

• If you have an allergy to this drug, any of its ingredients, other drugs, foods or substances. Tell your doctor about your allergies and how they have manifested.
• Under the following conditions: increased thyroid function or weakened adrenal glands.

This list of drugs and conditions that may interact with this drug is not exhaustive.

Tell your doctor and pharmacist about all medicines you take (prescription and over-the-counter, natural products and vitamins) and any health problems you have. You need to make sure that this drug is safe for your conditions and in combination with other drugs you are already taking. Do not start or stop taking any drug or change the dosage without your doctor’s advice.

What do I need to know or do while taking this drug?

All forms:

• Tell all your health care workers that you are taking this drug. These are doctors, nurses, pharmacists and dentists.
• Make sure that the drug does not run out.
• It may take several weeks to achieve full effect.
• If you have high blood sugar (diabetes), this drug can sometimes raise your blood sugar even more. Discuss with your doctor how you can keep your blood sugar under control.
• Check your blood sugar as directed by your doctor.
• Perform blood tests as directed by your doctor. Consult with your doctor.
• Taking this drug at excessively high doses can cause broken bones (osteoporosis). The risk may be higher after menopause. If you want to know if you are at increased risk for broken bones, or if you have any questions, check with your doctor.
• If you are 65 years of age or older, use this drug with caution. You may experience more side effects.
• In some cases, the drug may affect the growth rate in children and adolescents. They may need regular growth rate checks. Consult your doctor.
• Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding. The benefits and risks for you and your child will need to be discussed.

Injection:

• This drug is not approved for use in children. Consult your doctor.

What side effects should I report to my doctor immediately?

WARNING. In rare cases, this drug can cause serious and sometimes deadly side effects in some patients. Contact your doctor or seek medical attention right away if you have any of the following signs or symptoms that may be associated with serious side effects:

• Signs of an allergic reaction such as rash, hives, itching, red and swollen skin with blisters or peeling, possibly in combination with fever, wheezing or wheezing, tightness in the chest or throat, difficulty breathing, swallowing or speaking, unusual hoarseness, swelling in the mouth, face, lips, tongue or throat.
• Signs of high blood pressure, such as a very severe headache, or dizziness, or loss of consciousness, or blurred vision.
• Symptoms of too much thyroid hormone production in the body. These include heat intolerance; shiver; fatigue or weakness; anxiety, excitability, or irritability. They also include weight loss; change in appetite; temperature increase; increased sweating; headache; anxiety; emotional ups and downs; sleep disorders; muscle weakness or cramps; rapid or irregular heartbeat; chest pain, angina; shortness of breath, significant weight gain, swelling of the arms or legs; diarrhea vomiting; stomach cramps; hyperemia; bone pain disruption of the menstrual cycle; fertility disorders.

What are some other side effects of this drug?

Any medicine can have side effects. However, for many people, side effects are either minor or non-existent. Contact your doctor or seek medical attention if these or any other side effects bother you or do not go away:

• Some people may experience hair loss during the first few months of taking this drug. As a rule, this process is reversible.

This list of possible side effects is not exhaustive. If you have any questions about side effects, please contact your doctor. Talk to your doctor about side effects.

You can report side effects to the National Health Board.

You can report side effects to the FDA at 1-800-332-1088. You can also report side effects at https://www.fda.gov/medwatch.

What is the best way to take this drug?

Use this drug as directed by your doctor. Read all the information provided to you. Strictly follow all instructions.

Tablets:

• Take this drug at about the same time of day.
• If you are taking colesevelam, colestipol, cholestyramine, kyexalate, or sevelamer, do not take it within 4 hours before or 4 hours after taking this drug.
• Keep taking this drug as instructed by your doctor or other health care professional, even if you feel well.

Injection:

• For intravenous injections.

What if I miss a dose of a drug?

Tablets:

• Take the missed dose as soon as you can.
• If it’s time for your next dose, don’t take the missed dose and then go back to your regular dosing schedule.
• Do not take 2 doses or an additional dose at the same time.

Injection:

• See your doctor for further instructions.

How do I store and/or discard this drug?

Tablets:

• Store at room temperature in a dry place. Do not store in the bathroom.

Injection:

• If you need to store this drug at home, check with your doctor, nurse, or pharmacist for storage conditions.

All forms:

• Keep all medicines in a safe place. Keep all medicines out of the reach of children and pets.
• Dispose of unused or expired drugs. Do not empty into a toilet or sewer unless instructed to do so. If you have any questions about disposing of medicines, ask your pharmacist. Drug disposal programs may be in place in your area.

General information about medicines

• If your health does not improve or even worsens, see your doctor.
• Do not give your medicine to anyone and do not take other people’s medicines.
• Some medicines may come with other patient information leaflets. If you have questions about this drug, talk with your doctor, nurse, pharmacist, or other health care professional.
• Some medicines may come with other patient information leaflets. Check with your pharmacist. If you have questions about this drug, talk with your doctor, nurse, pharmacist, or other health care professional.
• If you think you have overdosed, call a poison control center or get medical help right away. Be prepared to tell or show what drug you took, how much, and when it happened.

Consumer Use of Information and Limitation of Liability

This summary information includes a summary of the diagnosis, treatment, and/or drug product. It is not intended to be a comprehensive source of data and should be used as a tool to help the user understand and/or evaluate potential diagnostic and treatment options. It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a particular patient. It should not be considered medical advice or a substitute for medical advice, diagnosis or treatment provided by a physician based on a medical examination and assessment of the patient’s specific and unique circumstances. Patients should consult with their physician for full information about their health, medical issues, and treatment options, including any risks or benefits regarding the use of medications. This information is not a guarantee that a treatment or drug is safe, effective, or approved for a particular patient. UpToDate, Inc. and its subsidiaries disclaim any warranties or liabilities related to this information or its use. The use of this information is subject to the Terms of Use found at https://www. wolterskluwer.com/en/know/clinical-effectiveness-terms.

Last revision date

2022-10-10

Copyright

© UpToDate, Inc. and its affiliates and/or licensors, 2023. All rights reserved.

Date last updated

Monday, December 12, 2022

What side effect can the Johnson & Johnson vaccine cause? – Kommersant FM

• Radio “Kommersant FM”

Cases of rare illness reported in US following Johnson & Johnson vaccination. But doctors say the effects of COVID-19 are more serious than the side effects of the vaccine. This is the Guillain-Barré syndrome. Because of this disease, the immune system attacks the nerve cells. According to the American regulator, there were only about 100 cases of the syndrome for 13 million injections. However, a side effect warning will be added to the drug label. Details are in the review of the foreign press on Kommersant FM.

Photo: Lucas Landau, Reuters

Photo: Lucas Landau, Reuters

According to The Wall Street Journal , Guillain-Barré syndrome can appear after an injection with adenovirus vaccines. These, in addition to Johnson & Johnson, include the drug from AstraZeneca. For vaccines based on modified RNA (these are Pfizer and Moderna), such effects are not typical. According to the American regulator, the syndrome appeared two weeks after vaccination – mainly in men over 50 years old.

Guillain-Barré syndrome is a very rare autoimmune disease that can cause muscle weakness, tingling in the arms and legs, difficulty walking and speaking, and paralysis. As The New York Times clarifies, most symptoms resolve within a few weeks, but in some cases the nerve damage may be permanent. Every year in the United States, the syndrome is detected in 3-6 thousand patients. Why the disease occurs is unknown. But often Guillain-Barré syndrome appears against the background of infections, such as influenza. There are also cases of illness after suffering COVID-19.

CNN clarifies that the injection rarely causes illness. Only 100 cases out of 13 million vaccinations are known. At the same time, 95 people were hospitalized, one died. US health authorities recommend not delaying vaccination. According to experts, during a large-scale vaccination campaign, rare side effects are always observed. The benefits of the vaccine outweigh the potential harm.

Although the syndrome is rare, this news could hit Johnson & Johnson and US plans to vaccinate as many people as possible, writes The Washington Post . There are high expectations for Janssen because it is one-component and can be easily transported due to the relatively high storage temperature. That is, the vaccine is especially useful for use in poor and hard-to-reach areas.

But information about new side effects may increase skepticism among those who have not yet been vaccinated, especially given Johnson & Johnson’s past problems.