Lasix water pills side effects. Navigating the Side Effects of Furosemide (Lasix): A Comprehensive Guide
What are the common and serious side effects of furosemide (Lasix) water pills? How can you manage them effectively? Discover the key information you need to know to use this medication safely.
Unraveling the Common Side Effects of Furosemide (Lasix)
Furosemide, commonly known as Lasix, is a potent diuretic medication used to treat various medical conditions, including edema, high blood pressure, and heart failure. While this medication can be highly effective, it can also bring about a range of common side effects that patients should be aware of.
Increased Urination
One of the most prevalent side effects of furosemide is increased urination. This is a natural consequence of the drug’s mechanism of action, as it works by promoting the excretion of excess fluid from the body. While this effect can be inconvenient, it is typically not a cause for concern and should subside within approximately 6 hours after taking the medication. If the frequent urination persists or becomes problematic, consider adjusting the timing of your dosage in consultation with your healthcare provider.
Dehydration and Electrolyte Imbalances
Furosemide can also lead to dehydration and electrolyte imbalances, such as low levels of sodium, potassium, and magnesium. To mitigate these risks, it’s essential to maintain proper hydration by drinking the recommended amount of fluids, as directed by your doctor. Additionally, your healthcare provider may prescribe supplemental electrolytes to help restore the balance and prevent complications.
Gastrointestinal Symptoms
Furosemide can sometimes cause gastrointestinal side effects, such as nausea, vomiting, and diarrhea. To minimize these issues, it’s recommended to take the medication with or immediately after a meal. If the symptoms persist or worsen, consult your healthcare provider, as dehydration can become a concern.
Dizziness and Confusion
Dizziness and confusion are other potential side effects of furosemide. These may be especially prevalent when standing up quickly, as the medication can cause a sudden drop in blood pressure. To mitigate this risk, it’s advised to rise slowly and avoid activities that could lead to falls or injury until the dizziness subsides.
Headaches and Fatigue
Headaches and fatigue are also common side effects associated with furosemide. Ensure adequate rest and hydration, and consider over-the-counter pain relievers if the headaches persist or become severe. If the fatigue or headaches are severe or last more than a week, consult your healthcare provider.
Addressing Serious Side Effects of Furosemide (Lasix)
In addition to the common side effects, furosemide can also lead to more serious adverse reactions that require immediate medical attention. These include:
Unexplained Bruising or Bleeding
If you experience unexplained bruising or bleeding while taking furosemide, it could be a sign of a blood disorder. Immediately contact your healthcare provider or call 111 for further guidance.
Severe Abdominal Pain
Severe abdominal pain that radiates to the back may be a sign of pancreatitis, a potentially serious condition. Seek medical care promptly if you experience this symptom.
Blood in Urine or Severe Kidney Pain
Experiencing blood in your urine or severe pain in your side may indicate inflamed kidneys. Report these symptoms to your healthcare provider immediately.
Hearing Loss or Ringing in the Ears
Furosemide can potentially cause hearing-related side effects, such as tinnitus (ringing in the ears) or hearing loss. If you experience these symptoms, contact your healthcare provider without delay.
Serious Allergic Reactions
In rare cases, furosemide can trigger a severe allergic reaction, known as anaphylaxis. Seek emergency medical care if you experience swelling of the lips, mouth, throat, or tongue, difficulty breathing, or a sudden change in consciousness or skin color.
Remember, while side effects can be concerning, it’s essential to follow your healthcare provider’s instructions and report any persistent or worsening symptoms promptly. With proper monitoring and management, you can safely and effectively use furosemide to address your medical needs.
Side effects of furosemide – NHS
Common side effects
These common side effects of furosemide happen in more than 1 in 100 people. There are things you can do to help cope with them:
Peeing more than normal
This will last for about 6 hours after taking furosemide. It’s nothing to worry about, but if it’s inconvenient for you, change the time you take furosemide to one that suits you better (provided it’s no later than 4pm).
If peeing a lot is still a problem for you, talk to your doctor or pharmacist.
Feeling thirsty
It’s important not to get dehydrated, but how much you drink will depend on why you’re taking furosemide.
Check with your doctor how much liquid you can drink while you’re taking this medicine.
Dry mouth
Chew sugar-free gum or suck sugar-free sweets.
Headaches
Make sure you rest and drink fluids – ask your doctor how much you can drink while taking this medicine. Do not drink too much alcohol.
Ask your pharmacist to recommend a painkiller. Talk to your doctor if the headaches last longer than a week or are severe.
Feeling confused or dizzy
If furosemide makes you feel dizzy when you stand up, try getting up very slowly or stay sitting down until you feel better. If you begin to feel dizzy, lie down so that you do not faint, then sit until you feel better.
Do not drive, ride a bike or use tools or machinery while you’re feeling dizzy.
Feeling or being sick (nausea or vomiting)
Take furosemide with or just after a meal or snack. Take small, regular sips of water or squash so you do not get dehydrated (ask your doctor how much fluid you can drink).
Speak to a pharmacist if you have signs of dehydration, such as peeing less than usual or having dark, strong-smelling pee.
If you take contraceptive pills and you’re being sick, your contraception may not protect you from pregnancy. Check the pill packet for advice.
Speak to a doctor or pharmacist if any of these side effects bother you or last more than a few days.
Serious side effects
Some people have serious side effects after taking furosemide.
Tell your doctor or call 111 now if you get:
- unexplained bruising or bleeding, a high temperature, sore throat and mouth ulcers – these could be signs of a blood disorder
- severe stomach pain which could reach through to your back – this could be a sign of an inflamed pancreas (pancreatitis)
- severe pain in your side or blood in your urine – these could be signs of inflamed kidneys
- ringing in your ears (tinnitus) or loss of hearing
Serious allergic reaction
In rare cases, it’s possible to have a serious allergic reaction (anaphylaxis) to furosemide.
Immediate action required: Call 999 now if:
- your lips, mouth, throat or tongue suddenly become swollen
- you’re breathing very fast or struggling to breathe (you may become very wheezy or feel like you’re choking or gasping for air)
- your throat feels tight or you’re struggling to swallow
- your skin, tongue or lips turn blue, grey or pale (if you have black or brown skin, this may be easier to see on the palms of your hands or soles of your feet)
- you suddenly become very confused, drowsy or dizzy
- someone faints and cannot be woken up
- a child is limp, floppy or not responding like they normally do (their head may fall to the side, backwards or forwards, or they may find it difficult to lift their head or focus on your face)
You or the person who’s unwell may also have a rash that’s swollen, raised, itchy, blistered or peeling.
These can be signs of a serious allergic reaction and may need immediate treatment in hospital.
Other side effects
These are not all the side effects of furosemide. For a full list, see the leaflet inside your medicine packet.
Information:
You can report any suspected side effect using the Yellow Card safety scheme.
Visit Yellow Card for further information.
Page last reviewed: 21 February 2022
Next review due: 21 February 2025
Lasix Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing
Warnings:
Furosemide is a very potent medication. Using too much of this drug can lead to serious water and salt/mineral loss. It is important that you are closely monitored by your doctor while taking this medication.
Tell your doctor right away if you become very thirsty or confused, or develop muscle cramps/weakness. See also Side Effects section.
Warnings:
Furosemide is a very potent medication. Using too much of this drug can lead to serious water and salt/mineral loss. It is important that you are closely monitored by your doctor while taking this medication. Tell your doctor right away if you become very thirsty or confused, or develop muscle cramps/weakness. See also Side Effects section.
… Show More
Uses
Furosemide is used to reduce extra fluid in the body (edema) caused by conditions such as heart failure, liver disease, and kidney disease. This can lessen symptoms such as shortness of breath and swelling in your arms, legs, and abdomen.This drug is also used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.Furosemide is a “water pill” (diuretic) that causes you to make more urine.
This helps your body get rid of extra water and salt.
How to use Lasix oral
Read the Patient Information Leaflet if available from your pharmacist before you start taking furosemide and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take this medication by mouth as directed by your doctor, with or without food, usually once or twice daily. It is best to avoid taking this medication within 4 hours of your bedtime to prevent having to get up to urinate.
Dosage is based on your medical condition, age, and response to treatment. For children, the dose is also based on weight. Older adults usually start with a lower dose to decrease the risk of side effects. Do not increase your dose or take it more often than directed.
Take this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time(s) of the day as directed. Keep taking this medication even if you feel well. Most people with high blood pressure do not feel sick.
Sucralfate, cholestyramine, and colestipol can decrease the absorption of furosemide. If you are taking any of these drugs, separate the timing of each dose from furosemide by at least 2 hours.
Tell your doctor if your condition does not improve or if it worsens (for example, your blood pressure readings remain high or increase).
Side Effects
Dizziness, lightheadedness, headache, or blurred vision may occur as your body adjusts to the medication. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.
Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
This medication may cause dehydration and electrolyte imbalance. Tell your doctor right away if you have any of these unlikely but serious side effects: muscle cramps, weakness, unusual tiredness, confusion, severe dizziness, fainting, drowsiness, unusual dry mouth/thirst, nausea, vomiting, fast/irregular heartbeat.
Tell your doctor right away if you have any serious side effects, including: signs of kidney problems (such as change in the amount of urine), numbness/tingling/pain/redness/swelling of the arms/legs, hearing changes (such as ringing in the ears, temporary or permanent decreased hearing/deafness), stomach/abdominal pain, yellowing eyes/skin.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Precautions
Before taking furosemide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, liver problems, inability to make urine, gout, lupus.
If you have diabetes, furosemide may make it harder to control your blood sugar. Check your blood sugar regularly as directed and share the results with your doctor.
Furosemide may reduce the potassium level in your blood. Your doctor may instruct you to add potassium-rich foods to your diet (such as bananas, orange juice) or prescribe potassium supplements to prevent potassium loss. Ask your doctor for more details.
This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps.
Use sunscreen and wear protective clothing when outdoors. Tell your doctor right away if you get sunburned or have skin blisters/redness.
This drug may make you dizzy or blur your vision. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).
Severe sweating, diarrhea, or vomiting can increase the risk of dehydration. Report prolonged diarrhea or vomiting to your doctor. Follow your doctor’s instructions about the amount of fluids you can drink.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Babies born early (premature infants) and children may be more sensitive to certain effects of this drug, such as kidney stones.
Older adults may be more sensitive to the effects of this drug, especially dizziness and water/mineral loss.
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
This drug passes into breast milk and may affect milk production. Consult your doctor before breast-feeding.
Interactions
See also the How to Use section.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.
Some products that may interact with this drug include: desmopressin, ethacrynic acid, lithium.
Some products have ingredients that could raise your blood pressure or worsen your swelling. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen).
This medication may interfere with certain lab tests (such as thyroid hormone levels), possibly causing false test results. Make sure lab personnel and all your doctors know you use this drug.
Does Lasix oral interact with other drugs you are taking?
Enter your medication into the WebMD interaction checker
Overdose
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: fainting, severe weakness, a severe decrease in the amount of urine.
Do not share this medication with others.
Lifestyle changes that may help this medication work better include exercising, stopping smoking, reducing stress, and changing your diet. Consult your doctor for more details.
Lab and/or medical tests (such as kidney function, blood mineral levels such as potassium) should be done while you are taking this medication.
Keep all medical and lab appointments. Consult your doctor for more details.
Check your blood pressure regularly while taking this medication. Learn how to monitor your own blood pressure at home, and share the results with your doctor.
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Images
Lasix 20 mg tablet
Color: whiteShape: ovalImprint: LASIX R
This medicine is a white, oval, tablet imprinted with “LASIX R”.
Lasix 40 mg tablet
Color: whiteShape: roundImprint: LASIX and logo 40
This medicine is a white, oval, tablet imprinted with “LASIX R”.
Lasix 80 mg tablet
Color: whiteShape: roundImprint: LASIX and logo 80
This medicine is a white, oval, tablet imprinted with “LASIX R”.
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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else.
A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
💊 Composition of Lasix ® ✅ Application of Lasix ® Keep for yourself Search for analogues Interaction Description of the active ingredients of the preparation Lasix ® The scientific information provided is general and cannot be used to make decisions. Update date: 2020.06.15 Marketing authorization holder: SANOFI INDIA Limited ATX code: C03CA01 (Furosemide) Active substance: Rec.INN WHO registered Dosage form
Release form, packaging and composition |
Against the background of course treatment, there is no weakening of the effect.
Reduces the level of atrial natriuretic factor in plasma, causes vasoconstriction.
5-1.5 hours. With anuria, T 1/2 can increase up to 1.5-2.5 hours, with combined renal and hepatic insufficiency – up to 11-20 hours.| E83.5 | Calcium metabolism disorders |
| G93.6 | Cerebral edema |
| I10 | Essential [primary] hypertension |
I50. 0 | Congestive heart failure |
| I50.1 | Left ventricular failure |
| J81 | Pulmonary edema |
| K74 | Fibrosis and cirrhosis of the liver |
| N04 | Nephrotic syndrome |
| O15 | Eclampsia |
Dosing regimen
The method of administration and dosing regimen of a particular drug depends on its form of release and other factors. The optimal dosage regimen is determined by the doctor. Compliance of the dosage form of a particular drug with indications for use and dosing regimen should be strictly observed.
Set individually, depending on the indications, clinical situation, age of the patient.
During treatment, the dosage regimen is adjusted depending on the magnitude of the diuretic response and the dynamics of the patient’s condition.
When taken orally, the initial dose for adults is 20-80 mg / day, then, if necessary, the dose is gradually increased to 600 mg / day. For children, a single dose is 1-2 mg / kg.
The maximum oral dose of for children is 6 mg/kg.
With intravenous (jet) or intramuscular administration, the dose for adults is 20-40 mg 1 time / day, in some cases – 2 times / day. For children, the initial daily dose for parenteral use is 1 mg / kg.
Side effects
From the side of the cardiovascular system: decrease in blood pressure, orthostatic hypotension, collapse, tachycardia, arrhythmias, decrease in BCC.
From the side of the central nervous system and peripheral nervous system: dizziness, headache, myasthenia gravis, cramps of the calf muscles (tetany), paresthesia, apathy, weakness, weakness, lethargy, drowsiness, confusion.
On the part of the senses: visual and hearing impairments.
From the digestive system: decreased appetite, dry mouth, thirst, nausea, vomiting, constipation or diarrhea, cholestatic jaundice, pancreatitis (exacerbation).
From the genitourinary system: oliguria, acute urinary retention (in patients with prostatic hypertrophy), interstitial nephritis, hematuria, decreased potency.
From the side of the hematopoietic system: leukopenia, thrombocytopenia, agranulocytosis, aplastic anemia.
From the side of water and electrolyte metabolism: hypovolemia, dehydration (risk of thrombosis and thromboembolism), hypokalemia, hyponatremia, hypochloremia, hypocalcemia, hypomagnesemia, metabolic alkalosis.
From the side of metabolism: hypovolemia, hypokalemia, hyponatremia, hypochloremia, hypokalemic metabolic alkalosis (as a result of these disorders – arterial hypotension, dizziness, dry mouth, thirst, arrhythmia, muscle weakness, convulsions), hyperuricemia (with possible exacerbation gout), hyperglycemia.
Allergic reactions: purpura, urticaria, exfoliative dermatitis, erythema multiforme exudative, vasculitis, necrotizing angiitis, pruritus, chills, fever, photosensitivity, anaphylactic shock.
Others: with intravenous administration (optional) – thrombophlebitis, kidney calcification in premature babies.
Contraindications
Acute glomerulonephritis, urethral stenosis, urinary tract stone obstruction, acute renal failure with anuria, hypokalemia, alkalosis, precomatous conditions, severe liver failure, hepatic coma and precoma, diabetic coma, hyperglycemic coma , hyperuricemia, gout , decompensated mitral or aortic stenosis, hypertrophic obstructive cardiomyopathy, increased central venous pressure (more than 10 mm Hg), arterial hypotension, acute myocardial infarction, pancreatitis, impaired water and electrolyte metabolism (hypovolemia, hyponatremia, hypokalemia, hypochloremia, hypocalcemia, hypomagnesemia), digitalis intoxication, hypersensitivity to furosemide.
Use in pregnancy and lactation
During pregnancy, furosemide should only be used for a short time and only if the expected benefit to the mother outweighs the potential risk to the fetus.
Since furosemide may be excreted in breast milk and may also suppress lactation, breastfeeding should be discontinued if necessary during lactation.
Use in hepatic dysfunction
Contraindicated in severe hepatic impairment, hepatic coma and precoma.
Use in disorders of kidney function
Contraindicated in acute glomerulonephritis, acute renal failure with anuria.
Use in elderly patients
Use with caution in elderly patients with severe atherosclerosis.
Special instructions
Use with caution in prostatic hyperplasia, SLE, hypoproteinemia (risk of developing ototoxicity), diabetes mellitus (reduced glucose tolerance), with stenosing atherosclerosis of the cerebral arteries, against the background of prolonged therapy with cardiac glycosides, in elderly patients with severe atherosclerosis, pregnancy (especially the first half), lactation.
Electrolyte disturbances should be corrected before starting treatment. During treatment with furosemide, it is necessary to control blood pressure, electrolyte and glucose levels in the blood serum, liver and kidney function.
For the prevention of hypokalemia, it is advisable to combine furosemide with potassium-sparing diuretics. With the simultaneous use of furosemide and hypoglycemic drugs, dose adjustment of the latter may be required.
It is not recommended to mix furosemide solution in the same syringe with any other drugs.
Influence on the ability to drive vehicles and mechanisms
When using furosemide, it is impossible to exclude the possibility of a decrease in the ability to concentrate, which is important for people who drive vehicles and work with mechanisms.
Drug interactions
Simultaneous use with antibiotics of the aminoglycoside group (including gentamicin, tobramycin) may increase the nephro- and ototoxic effect.
Furosemide reduces the clearance of gentamicin and increases plasma concentrations of gentamicin as well as tobramycin.
When used simultaneously with antibiotics of the cephalosporin group, which can cause impaired renal function, there is a risk of increased nephrotoxicity.
With simultaneous use with beta-agonists (including fenoterol, terbutaline, salbutamol) and with GCS, hypokalemia may increase.
When used simultaneously with hypoglycemic agents, insulin may reduce the effectiveness of hypoglycemic agents and insulin, because. furosemide has the ability to increase the content of glucose in the blood plasma.
When used simultaneously with ACE inhibitors, the antihypertensive effect is enhanced. Severe arterial hypotension is possible, especially after taking the first dose of furosemide, apparently due to hypovolemia, which leads to a transient increase in the hypotensive effect of ACE inhibitors. The risk of impaired renal function increases and the development of hypokalemia is not excluded.
When used simultaneously with furosemide, the effects of non-depolarizing muscle relaxants are enhanced.
When used simultaneously with indomethacin, other NSAIDs, a decrease in the diuretic effect is possible, apparently due to inhibition of prostaglandin synthesis in the kidneys and sodium retention in the body under the influence of indomethacin, which is a nonspecific COX inhibitor; decrease in antihypertensive effect.
Furosemide is believed to interact in a similar manner with other NSAIDs.
When used simultaneously with NSAIDs, which are selective COX-2 inhibitors, this interaction is much less pronounced or practically absent.
When used simultaneously with astemizole, the risk of developing arrhythmias increases.
Co-administration with vancomycin may increase oto- and nephrotoxicity.
With simultaneous use with digoxin, digitoxin, an increase in the toxicity of cardiac glycosides is possible, associated with the risk of developing hypokalemia while taking furosemide.
There are reports of the development of hyponatremia with simultaneous use with carbamazepine.
When co-administered with cholestyramine, colestipol, the absorption and diuretic effect of furosemide are reduced.
When used simultaneously with lithium carbonate, it is possible to enhance the effects of lithium due to an increase in its concentration in the blood plasma.
Co-administration with probenecid reduces the renal clearance of furosemide.
With simultaneous use with sotalol, hypokalemia and the development of ventricular arrhythmia of the “pirouette” type are possible.
When used simultaneously with theophylline, the concentration of theophylline in blood plasma may change.
When used simultaneously with phenytoin, the diuretic effect of furosemide is significantly reduced.
After intravenous administration of furosemide during therapy with chloral hydrate, increased sweating, a feeling of heat, instability of blood pressure, tachycardia are possible.
Co-administration with cisapride may increase hypokalemia.
Furosemide has been suggested to reduce the nephrotoxic effects of ciclosporin.
Co-administration with cisplatin may increase the ototoxic effect.
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Lasix ® . Description of the drug in the reference book Vidal.
Lasix instructions, price in pharmacies of Ukraine
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Creation date: 04/27/2021
Update date: 07/15/2023
Stock and delivery form:
- Tablets 40 mg No.
45. - Tablets 40 mg No. 50.
- Injection retail 10 mg per 1 ml, 2 ml ampoule, pack of 10 ampoules.
45.tablets:
- Active speech: furosemide 40 mg
- Additive speech: corn starch, pregelatinized corn starch, lactose , colloidal anhydrous silica, talc, Mg stearate.
Injection ampoules:
- Active speech: furosemide 10 mg per ml
- Additive speech: Na hydroxide, Na chloride, prepared water for injection.
Pharmacological action:
Speech intoxication with lasix – furosemide – shows diuretic action for blockade of intoxication of sodium and chloride ions in vishids part of the loop of Henle. In an insignificant world, Lasix affects the coiled tubules, whose mechanism is not related to antialdosteron activity, but to carbonic anhydrase. Lasix sprays with potassium, magnesium, calcium.
In case of intravenous administration of Lasix, building, it is necessary to reduce the arterial pressure, the pressure at the legenous artery, the preload and the pressure in the left duct.
The diuretic effect is already observed after 5 min.
When taken in the middle, the diuretic effect of lasix begins during the first year, reaching a maximum in 1.5-2 years, the effectiveness of the effective period becomes close to 7 years.
In the body, Lasix is metabolized and excreted, mainly in the presence of glucuronic acid.
Indication before congestion:
2. Forced diuresis.
3. Complex therapy of arterial hypertension.
Method of infusion:
The method of ingestion and the dose of guilt is established individually depending on the degree of damage to the water-electrolyte balance, the value of glomerular filtration. Nadal, dose correction is necessary, depending on the degree of severity of the patient, the magnitude of diuresis.
The drug is prescribed in the form of tablets, but it is not possible, otherwise it is necessary for an urgent camp, the drug is administered intravenously strumenevo, the hour of administration of lasix is not guilty but less than 1.5-2 hvilin.
In the middle stage of the severity of edema syndrome, the initial dose of lasixom should be 20-80 mg orally or 20-40 mg intravenously or intraperitoneally, with insufficient effect, the dose can be increased by 40 mg orally I will take 20 mg, like Lasix to be administered at a visual injection. A higher dose can be done not earlier, lower after 6-8 years, after taking the initial oral dose, not earlier, lower after 2 years, after parenteral administration. Dose adjustment is required until adequate diuresis appears. A one-time dose can be prescribed in this way, but it can be recognized as a one-time or double dose. The maximum effect of lasix is predicted, as the drug is administered 2-4 times a day.
For children, the dose is determined according to the type of body mass of the child and the method of administration of lasix.
The initial dose for oral administration should be 2 mg/kg, for injectable administration – 1 mg/kg. Potential for a dose increase of 2 mg/kg for oral administration and 1 mg/kg for parenteral administration. A higher dose can be done not earlier, lower after 6-8 years, after taking the initial oral dose, not earlier, lower after 2 years, after parenteral administration.
In complex treatment of arterial hypertension, the dose of lasix, as a rule, becomes 80 mg / dose, but the additional dose is divided into two doses. Further dose increase is not sufficient, with insufficient effect of varto, add other antihypertensive measures.
In case of congestion of the lungs, 40 mg intravenously inject strumene, with insufficient effect after 20 minutes, another 20-40 mg can be injected.
For forced diuresis, 20-40 mg of lasix is given as an intravenous infusion. Nadal the dose of lasix may change, depending on the water-electrolyte balance and become a patient.
Side effects:
In high doses of lasix, there is a change in BCC (volume of circulating blood), as a result of which blood clots develop and may thrombosis./155141801-56a193fa5f9b58b7d0c0cb5d.jpg)
Part of the side effect is the development of water-electrolytic disorders: alkalosis (including the increase in metabolic alkalosis in circulatory diabetes), deficiency of sodium, chlorine, calcium, potassium; disruption of biochemical blood powers: increase in creatinine, cholesterol, triglycerides, secic acid (from acute gout), glucose (especially in case of cirrhotic diabetes).
Possible allergic reactions, ranging from severe manifestations (purpura, dermatitis, sverbіzh, erythema) and up to anaphylactic shock.
Rarely blame blood side disorders: leukopenia, eosinophilia, hemolytic changes, agranulocytosis, thrombocytopenia.
In low-birth-weight or premature infants, lasix infection in early life can lead to non-closure of the Botallian duct.
Contraindications:
Contraindications: Electrolyte imbalance, intolerance to furosemide or any other component of Lasix, anuria, dehydration, O deficiency CC, hepatic coma, be it a stage, vaginess in terms of up to 12 days and lactation period.
Vagination:
In terms of up to 12 days of exposure to lasix, it is absolutely contraindicated, in more advanced terms, exposure to lasix can only be used for strictly indicated indications, but the building drug has penetrated ati through the placental barrier.
Relationship with other medical problems:
The development of hypokalemia when taken with lasix can lead to an increase in the effects of cardiac glycosides.
In the case of one-hour recognition of Lasix with glucocorticosteroids, carrying with it, more precise control of the electrolyte blood composition is necessary, and the combination of these drugs may lead to a risk of developing hypokalemia.
When Lasix is combined with cephalosporin antibiotics or aminoglycosides, it is possible to increase their level in the blood, and in the event of an increase in side effects.
Probenecid, phenytoin and NSAIDs may reduce the diuretic effect of lasix.
With one-hour recognition of IACF and lasix, the hypotensive effect may worsen, right up to the development of collapse or a decrease in the function of nirok and acute nirkov insufficiency.
Combination of Lasix with anti-diabetic drugs helps to correct the dose of the rest.
Building Lasix has a toxic effect on theophylline, lithium preparations and curariform drugs.
Overdose:
Overdosing with lasix is more likely to cause arterial hypotension, disruption of the balance of electrolytes, confusion, dryness of the mouth, damage to the eyes. Lіkuvannya spryamovane on vіdnovlennya water-electrolyte balance and normalization of bcc.
Wash the safety:
Save in the area protected from falling direct dormouse, at room temperature (17-26 degrees Celsius).
Lasix: instructions
LASIX®
(UA/4871/01/01)
Release form:
tablets 40 mg No.
45 (15×3): 15 tablets per strip, 3 strips per cardboard box
Stock:
1 tablet vengeance furosemide 40 mg
Manufacturer:
India
LASIX® NEO
(UA/13555/01/01)
Release form:
rozchin for іn' dose, 10 mg/ml; No.