What are the main uses of Loratadine 10mg. How should you take Loratadine for optimal results. What are the potential side effects of Loratadine 10mg. Is Loratadine safe for children and pregnant women. How does Loratadine work to relieve allergy symptoms. What precautions should be taken when using Loratadine. When should you seek medical attention while taking Loratadine.

Understanding Loratadine: An Effective Antihistamine for Allergy Relief

Loratadine is a widely used antihistamine medication that provides relief from various allergy symptoms. It works by reducing the effects of histamine, a natural chemical in the body responsible for allergic reactions. Available under brand names such as Claritin, Alavert, and Tavist ND, loratadine is commonly prescribed in 10mg doses for adults and children over 6 years old.

Are you wondering how loratadine differs from other antihistamines? Unlike some older antihistamines, loratadine is non-drowsy for most people, making it suitable for daytime use. It’s effective in treating a range of allergy symptoms, including sneezing, runny nose, watery eyes, and skin reactions like hives and rashes.

Key Benefits of Loratadine

• Non-drowsy formula for most users
• Fast-acting relief from allergy symptoms
• Long-lasting effects (typically 24 hours)
• Available over-the-counter in many countries
• Suitable for both seasonal and chronic allergies

Loratadine Dosage: Ensuring Optimal Efficacy and Safety

Proper dosage is crucial for the effectiveness and safety of loratadine. The standard dose for adults and children 6 years and older is 10mg once daily. However, dosage may vary based on age, specific conditions, and the form of loratadine being used.

Does the time of day matter when taking loratadine? While it can be taken at any time, many people find it most effective when taken in the morning to provide all-day relief. It’s important to follow the instructions on the label or as prescribed by your healthcare provider.

Dosage Guidelines for Different Age Groups

1. Adults and children 6 years and older: 10mg once daily
2. Children 2-5 years old: 5mg once daily
3. Children under 2 years: Not recommended without medical advice

Can you take more than the recommended dose of loratadine? It’s not advisable to exceed the recommended dosage, as it doesn’t increase effectiveness and may lead to side effects. Always consult with a healthcare professional before adjusting your dose.

Common Side Effects of Loratadine 10mg

While loratadine is generally well-tolerated, some users may experience side effects. Most side effects are mild and often subside as the body adjusts to the medication. However, it’s important to be aware of potential adverse reactions.

Which side effects are most commonly reported with loratadine use? The most frequent side effects include:

• Headache
• Fatigue or drowsiness
• Dry mouth
• Stomach discomfort
• Nervousness or hyperactivity (especially in children)

Should you stop taking loratadine if you experience side effects? In most cases, these side effects are not severe enough to warrant discontinuation. However, if side effects persist or worsen, it’s advisable to consult your healthcare provider.

Loratadine for Children: Safety and Efficacy Considerations

Loratadine can be an effective treatment for allergy symptoms in children, but special care must be taken regarding dosage and administration. The safety profile of loratadine in children is generally good, but there are important factors to consider.

Is loratadine safe for all children? Loratadine is approved for use in children 2 years and older. However, for children under 6, a lower dose of 5mg is typically recommended. It’s crucial to consult a pediatrician before giving loratadine to young children, especially those under 2 years old.

Tips for Administering Loratadine to Children

• Use the appropriate dosage form (liquid, chewable tablets) based on the child’s age and preference
• Follow dosage instructions carefully, using provided measuring devices for liquid forms
• Monitor for any unusual reactions or side effects
• Avoid giving loratadine with fruit juices, which may affect absorption

How long can children safely take loratadine? For seasonal allergies, loratadine can typically be used throughout the allergy season. For chronic allergies, long-term use should be discussed with a healthcare provider.

Loratadine During Pregnancy and Breastfeeding: What You Need to Know

The use of loratadine during pregnancy and breastfeeding is a topic of concern for many women. While antihistamines are often necessary for managing allergy symptoms, safety considerations are paramount during these sensitive periods.

Can pregnant women safely take loratadine? Current research suggests that loratadine is generally considered safe during pregnancy, with no increased risk of major birth defects observed. However, it’s always best to consult with a healthcare provider before using any medication during pregnancy.

Considerations for Breastfeeding Mothers

• Loratadine does pass into breast milk in small amounts
• It’s considered compatible with breastfeeding by most experts
• Monitor the infant for any unusual drowsiness or irritability
• Consider taking the dose immediately after nursing to minimize exposure

Are there alternative allergy treatments for pregnant or breastfeeding women? Non-medicinal approaches, such as avoiding allergens and using saline nasal sprays, may be preferable. If medication is necessary, your healthcare provider can help weigh the benefits and risks of different options.

Drug Interactions and Precautions with Loratadine

While loratadine is generally safe, it can interact with certain medications and medical conditions. Understanding these interactions and taking necessary precautions is crucial for safe and effective use of the medication.

Which medications should not be taken with loratadine? Loratadine may interact with:

• Certain antifungal medications (e.g., ketoconazole, itraconazole)
• Some antibiotics (e.g., erythromycin, clarithromycin)
• Medications that affect liver enzymes

Do any medical conditions contraindicate the use of loratadine? Individuals with liver or kidney disease should use loratadine with caution and may require dosage adjustments. Those with phenylketonuria (PKU) should be aware that some forms of loratadine contain phenylalanine.

Important Precautions

1. Inform all healthcare providers about your use of loratadine
2. Avoid alcohol consumption while taking loratadine
3. Be cautious when driving or operating machinery until you know how loratadine affects you
4. Do not exceed the recommended dose

How can you minimize the risk of drug interactions? Always provide a complete list of medications, including over-the-counter drugs and supplements, to your healthcare provider and pharmacist. They can help identify potential interactions and adjust your treatment plan if necessary.

Long-term Use of Loratadine: Benefits and Considerations

For individuals with chronic allergies, long-term use of loratadine may be necessary. While loratadine is generally safe for extended use, there are important factors to consider for those taking it regularly over long periods.

Is it safe to take loratadine daily for an extended period? Loratadine is considered safe for long-term use in most adults and children over 2 years old. However, it’s important to periodically reassess the need for continued treatment with your healthcare provider.

Benefits of Long-term Loratadine Use

• Consistent relief from chronic allergy symptoms
• Improved quality of life for allergy sufferers
• Potential reduction in the development of secondary conditions (e.g., sinusitis)
• Minimal risk of tolerance or dependence

Are there any risks associated with long-term loratadine use? While loratadine is generally well-tolerated, some individuals may experience ongoing side effects. Regular check-ups with a healthcare provider can help monitor for any potential long-term effects.

Tips for Safe Long-term Use

1. Schedule regular follow-ups with your allergist or primary care physician
2. Monitor for any changes in effectiveness or side effects
3. Consider periodic “drug holidays” to assess ongoing need, under medical supervision
4. Maintain a healthy lifestyle to support overall immune function

Can long-term use of loratadine lead to dependency? Unlike some medications, loratadine does not cause physical dependence. However, some users may develop a psychological reliance on the medication for symptom relief. Discussing alternative or complementary treatments with your healthcare provider can help manage this concern.

Alternatives to Loratadine: Exploring Other Allergy Treatment Options

While loratadine is an effective antihistamine for many people, it may not be suitable for everyone. Understanding alternative treatment options can help individuals find the most effective allergy management strategy for their specific needs.

What are some alternatives to loratadine for allergy relief? Other options include:

• Other second-generation antihistamines (e.g., cetirizine, fexofenadine)
• First-generation antihistamines (e.g., diphenhydramine) for short-term use
• Nasal corticosteroids for more severe or persistent symptoms
• Decongestants for nasal congestion (use with caution due to potential side effects)
• Leukotriene receptor antagonists (e.g., montelukast) for certain types of allergies

How do these alternatives compare to loratadine in terms of efficacy and side effects? Each medication has its own profile of benefits and potential side effects. For example, some may cause more drowsiness than loratadine, while others may be more effective for certain symptom types.

Non-Pharmacological Approaches to Allergy Management

1. Allergen avoidance strategies (e.g., using air purifiers, dust mite-proof bedding)
2. Nasal irrigation with saline solution
3. Immunotherapy (allergy shots or sublingual tablets) for long-term desensitization
4. Dietary modifications to reduce histamine intake
5. Stress reduction techniques, as stress can exacerbate allergy symptoms

Are natural remedies effective for allergy relief? Some people find relief with natural remedies such as butterbur, quercetin, or local honey. However, the efficacy of these treatments varies, and they should be used with caution and preferably under the guidance of a healthcare professional.

Choosing the right allergy treatment often involves trial and error. Working closely with an allergist or healthcare provider can help identify the most effective approach for your individual needs, whether it involves loratadine, another medication, or a combination of treatments.

Loratadine Uses, Dosage & Side Effects Guide

Generic name: loratadine [ lor-AT-a-deen ]
Brand names: Alavert, Claritin, Claritin Reditab, ohm Allergy Relief, Tavist ND, Wal-itin
Dosage forms: oral capsule (10 mg), oral syrup (5 mg/5 mL), oral tablet (10 mg), oral tablet, chewable (5 mg), oral tablet, disintegrating (10 mg; 5 mg)
Drug class: Antihistamines

Medically reviewed by Sophia Entringer, PharmD. Last updated on Oct 8, 2021.

What is loratadine?

Loratadine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Loratadine is used to treat sneezing, runny nose, watery eyes, hives, skin rash, hay fever, itching, and other cold or allergy symptoms.

Loratadine is also used to treat skin hives and itching in people with chronic skin reactions

Warnings

You should not take this medication if you are allergic to loratadine or to desloratadine (Clarinex).

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Some chewable dosage forms of loratadine may contain phenylalanine. Talk to your doctor before using these forms of loratadine if you have phenylketonuria (PKU).

Ask a doctor or pharmacist before taking this medicine if you have liver or kidney disease.

Before taking this medicine

Ask a doctor or pharmacist if loratadine is safe to use if you have ever had:

• kidney disease; or

• liver disease.

The disintegrating tablet may contain phenylalanine and could be harmful if you have phenylketonuria (PKU).

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

Do not give this medicine to a child younger than 2 years old without medical advice.

How should I take loratadine?

Use loratadine exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Cold or allergy medicine is usually taken only for a short time until your symptoms clear up.

Do not give this medicine to a child younger than 2 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Loratadine is usually taken once per day. Follow your doctor’s instructions.

Do not crush, chew, or break the regular tablet. Swallow the pill whole.

A child’s dose is based on age and some forms of loratadine are not for use in children younger than 6 years old. Carefully follow the dosing instructions provided with this medicine.

Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

The chewable tablet must be chewed before you swallow it.

To take the orally disintegrating tablet (Claritin RediTab, Alavert):

• Keep the tablet in its blister pack until you are ready to take it. Open the package and peel back the foil. Do not push a tablet through the foil or you may damage the tablet.

• Use dry hands to remove the tablet and place it in your mouth.

• Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing. If desired, you may drink liquid to help swallow the dissolved tablet.

Call your doctor if your symptoms do not improve, or if they get worse.

Store at room temperature away from moisture and heat.

Loratadine side effects

Get emergency medical help if you have signs of an allergic reaction to loratadine: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

Common loratadine side effects may include:

• headache;

• feeling tired or drowsy;

• stomach pain, vomiting;

• dry mouth; or

• feeling nervous or hyperactive.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Dosing information

Usual Adult Dose for Allergic Rhinitis:

10 mg orally once a day
-Maximum dose: 10 mg/day

Use: Temporary relief of symptoms associated with hay fever or other upper respiratory allergies (e.g., runny nose, itchy, watery eyes, sneezing, itching of the nose/throat)

Usual Adult Dose for Urticaria:

10 mg orally once a day
-Maximum dose: 10 mg/day

Use: Temporary relief of symptoms associated with hay fever or other upper respiratory allergies (e.g., runny nose, itchy, watery eyes, sneezing, itching of the nose/throat)

Usual Pediatric Dose for Allergic Rhinitis:

2 to 5 years: 5 mg orally once a day
-Maximum dose: 5 mg/day

6 years and older: 10 mg orally once a day
-Maximum dose: 10 mg/day

Use: Temporary relief of symptoms associated with hay fever or other upper respiratory allergies (e. g., runny nose, itchy, watery eyes, sneezing, itching of the nose/throat)

Usual Pediatric Dose for Urticaria:

2 to 5 years: 5 mg orally once a day
-Maximum dose: 5 mg/day

6 years and older: 10 mg orally once a day
-Maximum dose: 10 mg/day

Use: Temporary relief of symptoms associated with hay fever or other upper respiratory allergies (e.g., runny nose, itchy, watery eyes, sneezing, itching of the nose/throat)

What other drugs will affect loratadine?

Other drugs may interact with loratadine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

What happens if I miss a dose?

Loratadine is used when needed. Do not use loratadine more than once in a 24-hour period. Do not use two doses at one time.

What happens if I overdose?

Overdose symptoms may include headache, drowsiness, and fast or pounding heartbeat.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking loratadine?

Follow your doctor’s instructions about any restrictions on food, beverages, or activity.

Popular FAQ

Loratadine does not usually cause drowsiness and is considered a non-sedating antihistamine. However, some people may get sleepy so use caution before driving, operating machinery or performing other hazardous tasks until you know how loratadine affects you.

Loratadine (brand example: Claritin), an over-the-counter (OTC) non-sedating antihistamine, does not usually increase blood pressure when used alone as a single ingredient. Some OTC combination products do contain loratadine plus the decongestant pseudoephedrine (brand example: Claritin-D), which can raise your blood pressure. In the US, Claritin-D and the generic are normally kept behind the pharmacy counter. If you have high blood pressure, are being treated for high blood pressure, or have concerns about your blood pressure, ask your doctor before you use pseudoephedrine in any form.

Loratadine fully works within one hour after you take it and its effect should last for 24 hours. Your symptoms should start to improve in about 20 minutes. You only have to take loratadine once a day. Loratadine is an effective over-the-counter, non-sedating antihistamine used to treat sneezing, runny nose or watery eyes due to a cold or allergy, skin hives and itching.

Yes, you can give loratadine to dogs, it is usually well tolerated and is unlikely to produce side effects such as drowsiness that tend to happen with some of the older antihistamines, such as diphenhydramine (also known as Benadryl). The human form of loratadine is the same as the form administered to dogs and it can be purchased at any drug store or grocery store. Continue reading

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Patient resources

• Advanced Reading
• Loratadine Capsules and Tablets
• Loratadine Chewable Tablets
• Loratadine Orally Disintegrating Tablets
• Loratadine Liquid

Other brands

Claritin, Alavert, Claritin Reditabs, Children’s Claritin Allergy

Professional resources

• Prescribing Information

Related treatment guides

• Urticaria
• Allergic Rhinitis
• Allergies
• Physical Urticaria
• Allergic Reactions

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use loratadine only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Copyright 1996-2023 Cerner Multum, Inc. Version: 10.01.

Dosage, Side Effects, Uses, and More

If you have allergies, your doctor or pharmacist may recommend taking loratadine. It’s a generic drug that you can buy over the counter, which means you don’t need a prescription.

Loratadine is used in adults and certain children to treat upper respiratory allergies, such as hay fever or pet allergies. Loratadine can relieve symptoms of these allergies, such as:

• runny nose
• sneezing
• itchy nose or throat
• itchy, watery eyes

Loratadine basics

Loratadine belongs to a group of drugs called antihistamines.

Loratadine comes as a tablet that you swallow. It’s also available as a capsule, liquid solution, and dissolving tablet, but those are not covered in this article.

Read on to learn more about loratadine’s uses, side effects, and other important information.

Loratadine brand-name versions

Loratadine is a generic drug, which means it’s an exact copy of the active drug in a brand-name medication. The brand-name medication that loratadine is based on is called Claritin.

Generic drugs are thought to be as safe and effective as the brand-name drug they’re based on. In general, generics usually cost less than brand-name drugs do.

If you’d like to know more about taking Claritin instead of loratadine, talk with your doctor. And explore this Healthline article to learn more about the differences between generic and brand-name drugs.

The information below describes the loratadine dosage that’s commonly used or recommended. If you’re unsure about what dosage to take, ask your doctor or pharmacist.

Form

Loratadine comes as a tablet that you swallow.

Strength: 10 mg

The loratadine tablet is available in one strength of 10 milligrams (mg).

Recommended dosages

The usual loratadine dosage for adults is 10 mg taken once per day.

The usual dosage for children ages 6 years and older is 10 mg taken once per day.

The maximum dosage for adults and children taking loratadine is 10 mg in 24 hours.

Questions about loratadine’s dosage

Below are some common questions about loratadine’s dosage.

• Will I need to use loratadine long term? You should take loratadine only when needed to relieve your allergy symptoms. How long you need to take loratadine depends on what causes (or triggers) your allergy symptoms. For example, if you’re allergic to cats, you might take loratadine for a few days while visiting a friend with a cat. But if you’re allergic to grass pollen, you might want to take loratadine throughout the spring and summer.
• How long does loratadine take to work? Loratadine usually starts working about 1 hour after you take a dose.

Like most drugs, loratadine may cause mild or serious side effects. The lists below describe some of the more common side effects that loratadine may cause. These lists don’t include all possible side effects.

Keep in mind that side effects of a drug can depend on:

• your age
• other health conditions you have
• other medications you take

Your doctor or pharmacist can tell you more about the potential side effects of loratadine. They can also suggest ways to help reduce side effects.

Mild side effects

Here’s a short list of some of the mild side effects that loratadine can cause. To learn about other mild side effects, talk with your doctor or pharmacist.

Mild side effects of loratadine that have been reported include:

• headache
• diarrhea
• drowsiness
• dry mouth
• fatigue (low energy)
• mild allergic reaction*

Mild side effects of many drugs go away within a few days to a couple of weeks. But if they become bothersome, talk with your doctor or pharmacist.

* To learn more about this side effect, see the “Allergic reaction” section below.

Serious side effects

Serious side effects from loratadine can occur, but they aren’t common. If you have serious side effects from loratadine, call your doctor right away. But if you think you’re having a medical emergency, you should call 911 or your local emergency number.

Serious side effects of loratadine that have been reported include severe allergic reactions.To learn more about this side effect, see the “Allergic reaction” section below.

Allergic reaction

Some people may have an allergic reaction to loratadine. Although allergic reaction wasn’t reported in studies of loratadine, it can still happen.

Symptoms of a mild allergic reaction can include:

• skin rash
• itchiness
• flushing (temporary warmth, redness, or deepening of skin color)

A more severe allergic reaction is rare but possible. Symptoms of a severe allergic reaction can include swelling under your skin, usually in your eyelids, lips, hands, or feet. They can also include swelling of your tongue, mouth, or throat, which can cause trouble breathing.

Call your doctor right away if you have an allergic reaction to loratadine. But if you think you’re having a medical emergency, call 911 or your local emergency number.

Find answers to some commonly asked questions about loratadine.

How does loratadine compare with other similar drugs, such as cetirizine?

Loratadine belongs to a group of drugs called antihistamines. Other antihistamines available for treating allergies include:

• cetirizine (Zyrtec)
• fexofenadine (Allegra)
• diphenhydramine (Benadryl)
• desloratadine (Clarinex)

Most antihistamines are similarly effective, but you may find that one works better for you than another.

Your doctor or pharmacist may recommend a certain antihistamine depending on the symptoms you have. For example, loratadine is typically recommended for upper respiratory symptoms. Other antihistamines may be suggested for treating itching associated with hives or skin allergies.

Some antihistamines cause drowsiness. For example, diphenhydramine commonly causes drowsiness. When taken as directed, loratadine, fexofenadine, and cetirizine usually cause much less drowsiness.

To learn more about how loratadine compares with other antihistamines, talk with your doctor or pharmacist. They can help you decide which medication may be best for you.

Will loratadine make me drowsy or raise my blood pressure?

No, loratadine doesn’t usually cause these side effects.

Most people don’t feel drowsy or sleepy while taking loratadine as directed. But some people have reported mild drowsiness while taking loratadine.

High blood pressure has been reported with loratadine. It’s unknown how often this occurs, but it’s likely rare.

Can I take a 5-mg or 20-mg dose of loratadine?

No, with loratadine tablets, you should not take a 5-milligram (mg) or 20-mg dose.

The maximum recommended dosage of loratadine is 10 mg in 24 hours. Taking a higher dose of loratadine, such as 20 mg, may cause an antihistamine overdose or increase your risk of side effects.

The usual loratadine dosage is 10 mg taken once per day. A 5-mg dose of loratadine is probably not enough to relieve your allergy symptoms. Also, these tablets only come in a 10-mg strength. They’re not scored and not meant to be split in half.

For children ages 2 to 5 years, other forms of loratadine that are easier to take are available at lower doses. But loratadine tablets should not be used in children younger than 6 years old.

Is loratadine used for dogs?

Yes, veterinarians sometimes prescribe loratadine to treat allergies in dogs. But this is an off-label use for loratadine. (Off-label use refers to using a drug for a purpose that the FDA has not approved.)

You should not give loratadine to your dog unless your veterinarian has prescribed it. Your veterinarian can tell you more about using loratadine in pets.

Does loratadine cause long-term side effects?

No, loratadine isn’t known to cause any long-term side effects. It’s generally considered safe to take this drug long term.

If you’re concerned about long-term side effects with loratadine, talk with your doctor or pharmacist.

Can loratadine be used for cough or hives?

It depends. Loratadine is approved to treat upper respiratory allergies, such as hay fever. But in some cases, it can be used for symptoms of cough or hives.

Some people have a tickly cough with allergies, such as hay fever. The cough is caused by postnasal drip (mucus running down the back of your throat). Loratadine dries up the mucus in your nose, so it can help ease this type of tickly cough. But it’s unlikely to treat other causes of cough.

Loratadine isn’t typically used for skin allergies, such as hives. But antihistamines, such as loratadine, can relieve itching from hives. A brand-name form of loratadine called Claritin Hives Relief is one drug used to treat itching from hives.

Sometimes, doctors will prescribe loratadine with a stronger antihistamine that’s approved to treat hives, such as diphenhydramine (Benadryl). But if you want to take loratadine for hives, always talk with your doctor or pharmacist first.

There are a few things to consider before taking loratadine. The medication may interact with other conditions you have, other medications you take, and certain tests you may have. You should talk with your doctor or pharmacist about your health history and other treatments before taking loratadine.

Some things to consider are discussed below.

Interactions

Taking a medication with certain vaccines, foods, and other things can affect how the medication works. These effects are called interactions.

Before taking loratadine, be sure to tell your doctor or pharmacist about all medications you take (including prescription and over-the-counter types). Also, describe any vitamins, herbs, or supplements you use. Your doctor or pharmacist can tell you about any interactions these items may cause with loratadine.

For information about drug-condition interactions, see the “Warnings” section below.

Interactions with drugs or supplements

Loratadine doesn’t usually interact with other medications. But you may be more likely to feel drowsy or sleepy if you take it with other drugs that make you feel sleepy. Examples of these drugs include:

• sleeping pills
• some anxiety drugs
• sedating antihistamines, such as diphenhydramine (Benadryl)
• certain strong pain relievers

Loratadine should not be taken with other antihistamines unless your doctor prescribes the combination. (Loratadine is an antihistamine.)

This list does not contain all types of drugs that may interact with loratadine. Your doctor or pharmacist can tell you more about these interactions and any others that may occur when taking loratadine.

Other interactions

Loratadine can affect the results of allergy tests, such as skin tests you may have to check for certain allergies.

If you’re planning to have an allergy test done, your doctor will likely recommend that you do not take loratadine for a few days beforehand.

Warnings

Loratadine can sometimes cause harmful effects in people who have certain conditions. This is known as a drug-condition interaction. Other factors may also affect whether loratadine is a good treatment option for you.

Talk with your doctor about your health history before you take loratadine. Factors to consider include those described below.

Liver or kidney problems. Your liver and kidneys help remove loratadine from your body. If your liver or kidneys don’t work well, loratadine could build up in your body. This could raise your risk of side effects. If you have a liver or kidney problem, talk with your doctor before taking loratadine. They may recommend taking a dose every other day instead of every day.

Allergic reaction. If you’ve had an allergic reaction to loratadine or any of its ingredients, your doctor will likely recommend that you do not take loratadine. Ask them what other medications are better options for you.

Loratadine and alcohol

Loratadine isn’t known to interact with alcohol. But alcohol and loratadine can cause some of the same side effects, such as headache and fatigue (low energy). Combining alcohol and loratadine may raise your risk of having these side effects or may make them worse if you experience them.

Although loratadine doesn’t usually cause drowsiness, you may be more likely to feel drowsy if you drink alcohol while taking it.

If you drink alcohol, talk with your doctor about how much is safe to drink with loratadine.

Pregnancy and breastfeeding

It’s not known if loratadine is safe to take during pregnancy. If you’re pregnant or planning to become pregnant, talk with your doctor before taking loratadine.

It’s also not known if loratadine is safe to take while breastfeeding. Loratadine can pass into breast milk. But it’s not known how this drug may affect a breastfed child. If you’re breastfeeding or planning to breastfeed, talk with your doctor before taking loratadine.

Loratadine is used to treat the symptoms of upper respiratory allergies, such as hay fever.

Allergies occur when your immune system overreacts to a harmless substance. For example, your body may react to tiny particles you breathe in from the air, including:

• grass or tree pollen
• mold spores
• pet dander (skin flakes)
• dust mite waste

When this happens, cells in your immune system release histamine. Histamine causes inflammation. This leads to allergy symptoms, such as:

• runny nose
• sneezing
• itchy nose or throat
• itchy, watery eyes

Loratadine is an antihistamine. It relieves allergy symptoms by stopping histamine from acting on cells that cause inflammation.

You should not take more than 10 mg of loratadine in 24 hours. And you should not take loratadine with other antihistamines unless your doctor specifically prescribes them together. (Loratadine is an antihistamine.) Taking too much loratadine or more than one antihistamine at a time when you’re not directed to can cause an antihistamine overdose.

What to do in case you take too much loratadine

Call your doctor if you think you’ve taken too much loratadine. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource. But if you have severe symptoms, immediately call 911 or your local emergency number. Or go to the nearest emergency room.

Your doctor or pharmacist will explain how you should take loratadine. They’ll also explain how much to take and how often. Be sure to follow your doctor or pharmacist’s instructions.

Taking loratadine

Loratadine comes as a tablet that you swallow. You’ll take it once per day as needed to relieve allergy symptoms.

You should not take more than one dose in 24 hours.

Accessible medication containers and labels

If it’s hard for you to read the label on the medication, tell your doctor or pharmacist. Certain pharmacies provide medication labels that:

• have large print
• use braille
• contain a code you can scan with a smartphone to change the text to audio

Your doctor or pharmacist may be able to recommend a pharmacy that offers these options if your current pharmacy doesn’t.

Questions about taking loratadine

Below are some common questions about taking loratadine.

• Can loratadine be chewed, crushed, or split? Loratadine tablets are meant to be swallowed whole. If you have trouble swallowing loratadine tablets, talk with your doctor or pharmacist. Other forms of loratadine are available that may be easier for you to take.
• Should I take loratadine with food? You can take loratadine either with or without food.
• Is there a best time of day to take loratadine? No, you can take loratadine at any time of day. But if you’re taking it for more than 1 day, it’s best to take it around the same time each day. This helps the medication work effectively.

Prescription drug costs can vary depending on many factors. These factors include what your insurance plan covers and which pharmacy you use.

Financial assistance to help you pay for loratadine may be available. Medicine Assistance Tool and NeedyMeds are two websites that provide resources to help reduce the cost of loratadine.

These websites also offer tools to help you find low cost healthcare and certain educational resources. To learn more, visit their websites.

If you have questions about taking loratadine, talk with your doctor or pharmacist. Some examples of questions you may want to ask include:

• How effective is loratadine?
• Can I take loratadine to prevent allergies?
• How long should I take loratadine?
• Can I take loratadine with other allergy treatments?

To get information on different conditions and tips for improving your health, subscribe to any of Healthline’s newsletters. You may also want to check out the online communities at Bezzy. It’s a place where people with certain conditions can find support and connect with others.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

Loratadine – antihistamine drug, instructions for use and prices in pharmacies UA/5404/01/01

Unofficial Russian translation language of the text of the approved instructions for use of the medicinal product from Ukrainian

INSTRUCTION

for the medical use of the medicinal product

LORATADINE (LORATADINE)

Composition:

active ingredient: loratadine;

1 tablet contains loratadine in terms of 100% substance (0. 01 g) 10 mg;

excipients: potato starch, lactose monohydrate, povidone, calcium stearate.

Pharmaceutical form .

Tablets.

Basic physical and chemical properties: white round tablets with a flat surface, beveled and notched or not scored.

Pharmacotherapeutic group

Antihistamines for systemic use. ATX code R06A X13.

Pharmacological properties

Pharmacodinam and ca.

Loratadine is a tricyclic antihistamine with selective activity for peripheral H ₁ receptors.

In the majority of patients, when used at the recommended dose, loratadine does not have a clinically significant sedative and anticholinergic effect. During long-term treatment, there were no clinically significant changes in vital signs, laboratory tests, physical examination, or electrocardiogram. Loratadine has no significant effect on H ₂ histamine receptors. The drug does not inhibit the uptake of norepinephrine and does not actually affect the function of the cardiovascular system or the activity of the pacemaker of the heart.

Histamine skin test studies following a single dose of 10 mg have shown that the antihistamine effect occurs after 1-3 hours, peaks at 8-12 hours, and lasts for more than 24 hours. There was no development of tolerance to the action of the drug after 28 days of loratadine use.

Clinical efficacy and safety.

More than 10,000 patients (over 12 years of age) were treated with loratadine (10 mg tablets) in controlled clinical trials. Loratadine (tablets) 10 mg once daily was more effective than placebo and as effective as clemastine in improving symptoms (nasal and non-nasal) of allergic rhinitis. In these studies, drowsiness occurred at a lower rate with loratadine than with clemastine and at about the same rate as with terfenadine and placebo.

Among the participants in these studies (over 12 years of age), 1000 patients with chronic idiopathic urticaria were enrolled in placebo-controlled studies. Loratadine 10 mg once daily was more effective than placebo in the treatment of chronic idiopathic urticaria, as evidenced by a reduction in pruritus, erythema, and allergic rash. In these studies, the incidence of drowsiness was similar between loratadine and placebo.

Children. Approximately 200 children (6 to 12 years of age) with seasonal allergic rhinitis received loratadine (syrup) at doses up to 10 mg once daily in controlled clinical trials. In another study, 60 children (from 2 to 5 years) received loratadine (syrup) at a dose of 5 mg 1 time per day. Unforeseen adverse reactions were not observed. Efficacy in children was similar to that in adults.

Pharmacokinetics.

Suction. Loratadine is rapidly and well absorbed. The use of the drug during meals may slightly delay the absorption of loratadine, but this does not affect the clinical effect. The bioavailability of loratadine and its active metabolite is dose proportional.

Distribution. Loratadine binds actively (from 97% to 99%) with plasma proteins, and its active metabolite with moderate activity (from 73% to 76%). In healthy volunteers, the plasma half-life of loratadine and its active metabolite is approximately 1 and 2 hours, respectively.

Biotransformation. After oral administration, loratadine is rapidly and well absorbed and extensively metabolized during the first pass through the liver, mainly by CYP3A4 and CYP2D6. The main metabolite of desloratadine is pharmacologically active and is more responsible for the clinical effect. Loratadine and desloratadine reach maximum plasma concentrations (Tmax) after 1-1.5 hours and 1.5-3.7 hours, respectively, after the use of the drug.

Removal. Approximately 40% of the dose is excreted in the urine and 42% in the feces within 10 days, mainly in the form of conjugated metabolites. Approximately 27% of the dose is excreted in the urine during the first 24 hours. Less than 1% of the active substance is excreted in unchanged active form – as loratadine or desloratadine. In healthy adult volunteers, the mean half-life of loratadine was 8.4 hours (range, 3 to 20 hours) and the main active metabolite was 28 hours (range, 8.8 to 9 hours).2 hours).

Renal dysfunction. In patients with chronic renal impairment, the AUC and maximum plasma concentration (Cmax) of loratadine and its active metabolite increased compared to those in patients with normal renal function. The mean half-life of loratadine and its active metabolite did not differ significantly from that in healthy subjects. In patients with chronic hepatic impairment, hemodialysis does not affect the pharmacokinetics of loratadine and its active metabolite.

Liver dysfunction. In patients with chronic alcoholic liver disease, the AUC and Cmax of loratadine were two times higher, and their active metabolite did not change significantly compared with such indicators in patients with normal liver function. The half-life of loratadine and its active metabolite is 24 and 37 hours, respectively, and increases with the severity of liver disease.

Elderly patients. The pharmacokinetics of loratadine and its active metabolite were similar in healthy adult volunteers and healthy elderly volunteers.

Clinical characteristics.

Indications

Symptomatic treatment of chronic idiopathic urticaria and allergic rhinitis.

Contraindications

The drug is contraindicated in patients with hypersensitivity to the active substance or to any other component of the drug.

Interactions with other drugs and other types of interactions .

When used simultaneously with alcohol, the effects of loratadine are not enhanced, which is confirmed by studies of psychomotor function.

Potential interactions may occur with all known inhibitors of CYP3A4 or CYP2D6, leading to increased levels of loratadine, which in turn may lead to an increased incidence of adverse reactions.

An increase in plasma concentrations of loratadine has been reported after simultaneous use with ketoconazole, erythromycin and cimetidine, which was not accompanied by clinically significant changes (including ECG).

D e ti. Interaction studies with other drugs have only been performed in adults.

Application considerations

Loratadine should be used with caution in patients with severe hepatic impairment.

Contains lactose. Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency and glucose-galactose malabsorption should not take this medicine.

Loratadine should be discontinued at least 48 hours prior to skin testing, as antihistamines may neutralize or otherwise reduce a positive skin reactivity index response.

Use during pregnancy or lactation.

Pregnancy. A significant amount of data on use during pregnancy (more than 1000 results) indicates that loratadine does not cause malformations and is not toxic to the fetus and newborn. Animal studies have shown no direct or indirect adverse effects regarding reproductive toxicity. It is advisable, as a safety measure, to avoid the use of Loratadine during pregnancy.

Breastfeeding. Physicochemical data suggest that loratadine/metabolites are excreted in breast milk. Since a risk to the child cannot be ruled out, Loratadine should not be used during breastfeeding.

Fertile o Data on the effect of loratadine on female or male fertility are not available.

Ability to influence at speed response at steering 900 09 motor transport or other mechanisms .

No changes were observed in patients treated with loratadine in clinical studies of driving ability. The drug does not affect or slightly affects the ability to drive vehicles or other mechanisms. However, the patient must be informed that very rarely reported cases of drowsiness, which may affect the ability to drive vehicles or work with other mechanisms.

Method administration and doses

Orally. The tablets can be taken with or without food.

Adults and children over 12 years of age take 1 tablet (10 mg loratadine) once daily.

For children from 2 to 12 years of age, the dosage depends on body weight. With a body weight of more than 30 kg: 10 mg (1 tablet) 1 time per day. For children weighing less than 30 kg, use loratadine syrup.

Elderly patients . Dosage adjustment is not required for the elderly.

Patients with impaired liver function . Patients with severe hepatic impairment should be given a lower initial dose, as they may have decreased clearance of loratadine. For adults and children weighing over 30 kg, the recommended starting dose is 10 mg every other day.

Patients with impaired renal function . There is no need for dose adjustment for patients with impaired renal function.

D e ti .

The safety and efficacy of loratadine in children under 2 years of age has not been established. The drug Loratadin, tablets, is prescribed for children weighing more than 30 kg.

Overdose.

Overdose of loratadine increases the incidence of anticholinergic symptoms. In case of overdose, drowsiness, tachycardia and headache have been reported. In case of overdose, symptomatic and supportive treatment is recommended for the required period of time. It is possible to use activated carbon in the form of an aqueous suspension. You can also do gastric lavage. Loratadine is not excreted from the body during hemodialysis; the effectiveness of peritoneal dialysis in removing the drug is unknown. After an emergency, the patient should remain under medical supervision.

Side reactions

Cr profile characteristic without about n accessories . In clinical studies involving adults and adolescents, when using loratadine at the recommended dose of 10 mg per day for indications including allergic rhinitis and chronic idiopathic urticaria, adverse reactions were reported in 2% of patients (which is higher than in patients who received placebo). Adverse reactions reported more frequently than placebo were drowsiness (1.2%), headache (0.6%), increased appetite (0.5%), and insomnia (0.1%). In clinical studies in children 2 to 12 years of age, adverse events such as headache (2.7%), nervousness (2.3%) or fatigue (1%) were noted.

List of adverse reactions. Adverse reactions reported during the post-marketing period are listed below by organ system class. Frequency defined as: very common (≥1/10), common (≥1/100 to <1/10), rare (≥1/1000 to <1/100), isolated cases (≥1/10 ) 000 to <1/1000), rare cases (<1/10000) and the frequency is unknown (cannot be determined from the available data).

In each frequency group, adverse reactions are listed in decreasing order of severity.

From the immune system: rare cases – hypersensitivity reactions, including anaphylaxis and angioedema.

From the nervous system: rare cases – dizziness, convulsions.

From the side of the heart: rare cases – tachycardia, palpitation.

From the gastrointestinal tract: rare cases – nausea, dry mouth, gastritis.

Hepatobiliary system side s: rare cases – pathological changes in liver function.

From the side of the skin and subcutaneous tissue : rare cases – rash, alopecia.

Violations of the general condition and related to the method of application of the drug: rare cases – fatigue.

Studies : frequency unknown – weight gain.

Expiration date.

4 years.

Do not use after the expiry date which is stated on the pack.

Storage conditions.

Store in the original container at a temperature not exceeding 25 ^o C.

Keep out of the reach of children.

Packaging.

10 tablets in a blister. 1 or 2 blisters in a pack.

Vacation category.

Without a prescription.

Manufacturer.

Farmak JSC.

Manufacturer’s location and address of the place of business.

Ukraine, 04080, Kyiv, st. Kirillovskaya, 74.

Date of last revision. 02/22/2021.

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Loratadine tablets 10mg №30 with free home delivery from VkusVill

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Loratadin is a tricyclic compound with a pronounced antihistamine effect and is a selective blocker of peripheral H1-histamine receptors. Possesses fast and long antiallergic action. The onset of action is within 30 minutes after ingestion.

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Description

Loratadine is a tricyclic compound with a pronounced antihistamine effect and is a selective blocker of peripheral H1-histamine receptors. Possesses fast and long antiallergic action. The onset of action is within 30 minutes after ingestion.