What are the primary uses of methylcellulose. How does methylcellulose work as a laxative. What are the potential side effects of taking methylcellulose. How should methylcellulose be properly dosed and administered. Who should avoid using methylcellulose. What precautions should be taken when using methylcellulose.

Understanding Methylcellulose and Its Functions

Methylcellulose, commonly known by the brand name Citrucel, is a bulk-forming laxative used primarily to treat constipation and maintain regular bowel movements. This medication works by increasing the amount of water in stools, making them softer and easier to pass. By adding bulk to the stool, methylcellulose helps stimulate intestinal movement, promoting more frequent and comfortable bowel movements.

Beyond its primary use as a laxative, methylcellulose has found applications in other areas of medicine and even in food production. Its ability to form gels and act as a thickener has made it a versatile substance in various industries.

How does methylcellulose differ from other laxatives?

Unlike stimulant laxatives that directly trigger intestinal contractions, methylcellulose works more gently by altering the physical properties of the stool. This mechanism of action tends to produce fewer side effects and is generally considered safer for long-term use compared to other types of laxatives.

Medical Uses of Methylcellulose

The primary medical use of methylcellulose is in the treatment of constipation. However, its applications extend beyond this common digestive issue. Here are some of the key uses:

• Treating acute and chronic constipation
• Maintaining regular bowel movements
• Managing symptoms of irritable bowel syndrome (IBS)
• Assisting in the management of hemorrhoids by reducing straining
• Helping to regulate bowel movements in individuals with limited mobility

In some cases, healthcare providers may recommend methylcellulose for off-label uses, such as managing diarrhea by adding bulk to loose stools. However, it’s crucial to consult a healthcare professional before using methylcellulose for any purpose other than its primary indicated use.

Can methylcellulose be used to treat other digestive disorders?

While primarily used for constipation, some studies suggest that methylcellulose may have potential benefits in managing other digestive issues. For instance, its ability to add bulk to stools can sometimes help regulate bowel movements in people with mild diarrhea. However, more research is needed to fully understand its efficacy in treating other digestive disorders.

Proper Administration and Dosage Guidelines

Correct administration of methylcellulose is crucial for its effectiveness and safety. Here are the general guidelines for taking this medication:

1. Always follow the instructions provided by your healthcare provider or on the product label.
2. Take methylcellulose with a full glass of water (8 ounces or 240 milliliters) to prevent choking.
3. If using the powder form, mix it thoroughly in water or another liquid before consuming.
4. For wafer forms, chew thoroughly before swallowing.
5. Avoid taking methylcellulose immediately before bedtime.

The typical dosage for adults and children 12 years and older is 1 to 2 tablespoons of powder or 2 to 4 capsules, taken 1 to 3 times daily. However, dosage may vary based on individual needs and the specific product used.

How long does it take for methylcellulose to work?

Methylcellulose typically takes 12 to 72 hours to produce a bowel movement. This gradual onset of action is due to its mechanism of absorbing water and adding bulk to the stool, which takes time to affect bowel movements. If you don’t experience a bowel movement after 3 days of use, consult your healthcare provider.

Potential Side Effects and Risks

While methylcellulose is generally well-tolerated, like all medications, it can cause side effects in some individuals. Common side effects may include:

• Bloating
• Gas
• Mild stomach discomfort

More severe side effects, though rare, can occur. Seek immediate medical attention if you experience:

• Severe stomach cramps
• Rectal bleeding
• Signs of an allergic reaction (hives, difficulty breathing, swelling of face, lips, tongue, or throat)

It’s important to note that these lists are not exhaustive, and you should consult your healthcare provider about any persistent or concerning symptoms.

Are there any long-term risks associated with methylcellulose use?

When used as directed, methylcellulose is generally considered safe for long-term use. Unlike stimulant laxatives, it doesn’t typically lead to dependence or a loss of normal bowel function over time. However, relying on any laxative long-term without addressing underlying causes of constipation is not recommended. Always consult with a healthcare provider for prolonged use of any medication.

Interactions and Precautions

While methylcellulose is generally safe, it can interact with other medications and may not be suitable for everyone. Here are some important precautions:

• Take methylcellulose at least 2 hours before or after other medications, as it may affect their absorption.
• Inform your doctor if you have any medical conditions, especially irritable bowel syndrome, trouble swallowing, or unexplained stomach pain.
• Some methylcellulose products may contain phenylalanine, which can be problematic for people with phenylketonuria (PKU).
• Consult your doctor before using methylcellulose if you’re pregnant or breastfeeding.

It’s crucial to disclose all medications, supplements, and herbal products you’re taking to your healthcare provider before starting methylcellulose.

Can methylcellulose interact with common medications?

Methylcellulose can potentially interact with various medications by affecting their absorption. Some common medications that may interact include blood thinners, diabetes medications, and certain heart medications. To minimize the risk of interactions, it’s recommended to take methylcellulose at least 2 hours before or after other medications.

Special Considerations for Different Age Groups

The use of methylcellulose can vary depending on age. Here are some specific considerations:

Children

Methylcellulose is generally not recommended for children under 6 years old without medical advice. For older children, dosage should be adjusted based on age and weight.

Elderly

Older adults may be more sensitive to the effects of methylcellulose and may require lower doses. They should also be monitored more closely for side effects.

Pregnant and Breastfeeding Women

While methylcellulose is considered relatively safe during pregnancy and breastfeeding, it’s essential to consult a healthcare provider before use.

How does the efficacy of methylcellulose change with age?

The effectiveness of methylcellulose can vary with age due to changes in digestive function and overall health. Older adults may experience a more pronounced effect due to slower digestion and decreased muscle tone in the intestines. Conversely, children may require different dosages to achieve the desired effect. It’s crucial to follow age-specific dosing guidelines and consult with a healthcare provider for personalized advice.

Alternatives to Methylcellulose

While methylcellulose is an effective laxative for many, it’s not the only option available. Other bulk-forming laxatives and alternative treatments for constipation include:

• Psyllium (Metamucil)
• Polycarbophil (FiberCon)
• Natural dietary fiber sources (e.g., fruits, vegetables, whole grains)
• Stool softeners (e.g., docusate sodium)
• Osmotic laxatives (e.g., polyethylene glycol)

Each of these alternatives has its own set of benefits and potential side effects. The choice of laxative should be based on individual needs, medical history, and healthcare provider recommendations.

How do natural alternatives compare to methylcellulose in effectiveness?

Natural alternatives like dietary fiber from food sources can be as effective as methylcellulose for many people, especially when combined with adequate hydration and regular exercise. However, the onset of action may be slower and less predictable compared to methylcellulose. Some individuals may find that a combination of natural methods and occasional use of methylcellulose or other laxatives provides the best balance for managing constipation.

Lifestyle Changes to Complement Methylcellulose Use

While methylcellulose can be effective in treating constipation, it’s often most beneficial when combined with lifestyle changes. Here are some strategies to enhance the effectiveness of methylcellulose and promote overall digestive health:

1. Increase dietary fiber intake through fruits, vegetables, and whole grains
2. Stay well-hydrated by drinking plenty of water throughout the day
3. Engage in regular physical activity to stimulate bowel movements
4. Establish a regular toilet routine, allowing sufficient time for bowel movements
5. Avoid holding in bowel movements when the urge arises
6. Manage stress through relaxation techniques or counseling if needed

These lifestyle modifications can not only enhance the effectiveness of methylcellulose but may also reduce the need for laxatives over time.

How can diet modifications improve the effectiveness of methylcellulose?

Dietary modifications can significantly enhance the effectiveness of methylcellulose. Increasing fiber intake through whole grains, fruits, and vegetables can work synergistically with methylcellulose to add bulk to stools and promote regular bowel movements. Additionally, staying well-hydrated is crucial, as both methylcellulose and dietary fiber require adequate fluid to function optimally. Avoiding foods that may contribute to constipation, such as processed foods high in fat and sugar, can also improve overall digestive health and the effectiveness of methylcellulose.

Understanding Constipation and Its Causes

To fully appreciate the role of methylcellulose in treating constipation, it’s important to understand the condition itself. Constipation is generally defined as having fewer than three bowel movements per week, often accompanied by hard, dry stools that are difficult to pass.

Common causes of constipation include:

• Inadequate fiber intake
• Dehydration
• Lack of physical activity
• Certain medications (e.g., opioids, antidepressants)
• Medical conditions (e.g., hypothyroidism, diabetes)
• Changes in routine or travel
• Ignoring the urge to have a bowel movement

Understanding the underlying cause of constipation can help in determining the most appropriate treatment approach, which may or may not include methylcellulose.

When should one consider using methylcellulose for constipation?

Methylcellulose should be considered when lifestyle changes alone are not sufficient to relieve constipation. It’s particularly useful for occasional constipation or when trying to establish a more regular bowel routine. However, if constipation is chronic or accompanied by other symptoms like unexplained weight loss or rectal bleeding, it’s crucial to consult a healthcare provider before starting any laxative regimen, including methylcellulose.

In conclusion, methylcellulose is a valuable tool in managing constipation and maintaining regular bowel movements. Its gentle mechanism of action, coupled with relatively few side effects, makes it a popular choice among both healthcare providers and patients. However, like any medication, it should be used responsibly and in conjunction with lifestyle modifications for optimal results. Always consult with a healthcare professional for personalized advice on using methylcellulose or any other treatment for digestive issues.

Methylcellulose (Citrucel) – Side Effects, Interactions, Uses, Dosage, Warnings

Reviewed: June 23, 2020

Methylcellulose is a bulk-forming laxative that increases the amount of water in your stools to help make them softer and easier to pass.

Methylcellulose is used to treat constipation and to help maintain regular bowel movements.

Methylcellulose may also be used for purposes not listed in this medication guide.

uses

What is Methylcellulose (Citrucel) used for?

• Constipation

warnings

What is the most important information I should know about Methylcellulose (Citrucel)?

You should not take methylcellulose if you are allergic to it.

Ask a doctor or pharmacist if it is safe for you to use this medicine if you have other medical conditions, especially:

• irritable bowel syndrome;
• trouble swallowing;
• stomach pain with nausea or vomiting;
• a sudden change in bowel habits that lasts 2 weeks or longer; or
• if you have been constipated for more than 1 week.

This medicine may contain phenylalanine. Talk to your doctor before using methylcellulose if you have phenylketonuria (PKU).

Ask your doctor before taking methylcellulose if you are pregnant or breast-feeding a baby.

Do not give this medicine to a child younger than 6 years old without medical advice.

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Side Effects

What are the side effects of Methylcellulose (Citrucel)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• severe stomach cramps, rectal bleeding; or
• no bowel movement within 3 days after using methylcellulose.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I take Methylcellulose (Citrucel) if I’m pregnant or breastfeeding?

Ask your doctor before taking methylcellulose if you are pregnant or breast-feeding a baby.

Interactions

What drugs and food should I avoid while taking Methylcellulose (Citrucel)?

Follow your doctor’s instructions about any restrictions on food, beverages, or activity.

Dosage Guidelines & Tips

How to take Methylcellulose (Citrucel)?

Use Methylcellulose (Citrucel) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

What should I do if I missed a dose of Methylcellulose (Citrucel)?

Since methylcellulose is used when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

Overdose Signs

What happens if I overdose on Methylcellulose (Citrucel)?

If you think you or someone else may have overdosed on: Methylcellulose (Citrucel),  call your doctor or the Poison Control center

(800) 222-1222

If someone collapses or isn’t breathing after taking Methylcellulose (Citrucel), call 911

911

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G188

Color: orange

Shape: capsule

Imprint: G188

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Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. Cerner Multum™ provides the data within some of the Overview, Uses, Warnings, Side Effects, Pregnancy, Interactions, Dosage, Overdose, and Images sections. The information within all other sections is proprietary to Everyday Health.  

Methylcellulose (Laxative) Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Uses

This medication is used to treat constipation. It increases the bulk in your stool, an effect that helps to cause movement of the intestines. It also works by increasing the amount of water in the stool, making the stool softer and easier to pass.Psyllium, one type of bulk-forming laxative, has also been used along with a proper diet to treat high cholesterol.

How to use Methylcellulose (Laxative) Oral Powder

Take this medication by mouth as directed by your doctor. If you are self-treating, follow all directions on the product package. If you have any questions, ask your doctor or pharmacist. To prevent choking from this medication, take it with a full glass of water or other liquid (8 ounces/240 milliliters). If you are taking the wafers, chew them thoroughly before swallowing.

For powder forms of this medication, measure each dose according to the directions on the product label. Mix in a full glass of water or other liquid (8 ounces/240 milliliters), stir completely, and drink right away. You may add more liquid to the mixture if it becomes too thick. When preparing the medication, be careful not to breathe in the powder since it may rarely cause an allergic reaction.

Dosage is based on your age, medical condition, and response to treatment. Do not increase your dose or take this drug more often than directed.

This product may decrease the absorption of other medications you may be taking. Take this product at least 2 hours from your other medications. Ask your doctor or pharmacist for more information or if you have any questions.

It may take 1 to 3 days before this medication starts working. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day. Do not take this medication for more than 7 days unless directed by your doctor.

Tell your doctor if your condition lasts or gets worse, or if bleeding from the rectum occurs. If you think you may have a serious medical problem, get medical help right away.

Side Effects

Gas or stomach cramping may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

If your doctor has directed you to use this product, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

This product must be taken with at least a full glass of water or other liquid (8 ounces/240 milliliters) so that it will not swell in the throat, causing choking. Get medical help right away if after taking this product you have symptoms of choking such as: chest pain, vomiting, difficulty swallowing/breathing.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking this bulk-forming laxative, tell your doctor or pharmacist if you are allergic it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: stomach/intestinal blockage, difficulty swallowing, appendicitis or symptoms of appendicitis (such as nausea/vomiting, sudden or unexplained stomach/abdominal pain), a sudden change in bowel habits that lasts for longer than 2 weeks, bleeding from the rectum.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Some products may contain sugar and/or aspartame. Caution is advised if you have diabetes, phenylketonuria (PKU), or any other condition that requires you to limit/avoid these substances in your diet. Ask your doctor or pharmacist about using this product safely.

Tell your doctor if you are pregnant before using this medication.

It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Interactions

See also How To Use section.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

Does Methylcellulose (Laxative) Oral Powder interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Keep all medical and lab appointments.

Lifestyle changes that may prevent or relieve constipation include exercising, drinking enough water, and eating a proper diet with fiber-rich foods such as bran, fresh fruits/vegetables. Talk to your doctor or pharmacist about lifestyle changes that might benefit you.

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Different brands of this medication have different storage needs. Check the product package for instructions on how to store your brand, or ask your pharmacist. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

Leocaine solution 0.3% with methylcellulose

All forms of release, dosages, registration certificates, drug manufacturers, drug characteristics

Description of the drug Leocaine solution 0. 3% with methylcellulose (sterile solution, 0.3%) based on the official instructions, approved by the manufacturer in 1996

Date of approval: 31.07.1996

Contents

• Active substance
• ATX
• Pharmacological group
• Nosological classification (ICD-10)
• Composition and form of release
• pharmachologic effect
• Characteristic
• Indications
• Contraindications
• Dosage and administration
• Side effects
• Storage conditions
• Best before date

Active ingredient

Dimethylaminoethyl ether n-butylaminobenzoic acid hydrochloride

ATX

N01BA03 Tetracaine

Pharmacological group

Local anesthetics

Nosological classification (ICD-10)

ICD-10 code list

Composition and formulation

Solution of leocaine (beta-dimethylaminoethyl ester of parabutylaminobenzoic acid hydrochloride (beta form) 0. 3% with methylcellulose contains leocaine, sodium chloride, methylcellulose, purified water, in vials of 5 ml or 10 m L.

Pharmacological action

Pharmacological action –

local anesthetic .

Characteristics

Clear or slightly opalescent, colorless or slightly colored liquid.

Indications

Terminal anesthesia (in adults and children over 10 years old) for various endoscopic examinations, for pain relief during short-term operations and manipulations in dental, otorhinolaryngological, urological, gynecological practice. Conservative treatment of pain syndrome in superficial pathological processes.

Contraindications

Individual intolerance.

Dosage and Administration

Information for healthcare professionals only.
Are you a healthcare professional?

Local. In endoscopic practice, it is applied to the mucous membranes immediately before the examination at a time from 2 to 20 ml. In dentistry, it is used as an application on the surface to be surgically intervened, or on the affected area of ​​the oral mucosa for 1–1.5 minutes. To stop the pain syndrome in the conservative treatment of dental diseases, an application is made from 2-4 drops to 1-2 ml 3-4 times a day. In otorhinolaryngology – instillations or applications (1-1.5 minutes) immediately before surgery or manipulation in an amount of 2-4 drops to 1-2 ml. In gynecology – in the form of applications on the area of ​​the mucous membrane subject to surgical intervention, from 2-4 drops to 1-2 ml at a time. If necessary, during the surgical intervention, the applications are repeated depending on the duration of the operation and the individual tolerance of the drug to patients. The maximum dose of the drug in all cases should not exceed 30 ml per day.

Side effects

Mild discomfort at the site of application or instillation, allergic reactions.

Storage conditions

In a cool place.

Keep out of reach of children.

Expiration date

2 years.

Do not use after the expiry date which is stated on the packaging.

Updated: 04/23/2019

Information for healthcare professionals only.
Are you a healthcare professional?

Methylcellulose or E461 – the use of a food additive in construction and food industry

Published: 12/10/2016 properties of food additive E 461. Why a builder? It is in this area that the product of chemical synthesis has gained popularity.

You can also find it in sausage and ketchup, fluffy bun and milk dessert. Doctors question the benefits of supplements.

Contents: Show

• Product name
• Substance type
• Properties
• Packaging
• Application
• Benefits and harms
• Main manufacturers 90 021

Product name

Methylcellulose is the official name of the food additive. The international synonym is Methyl cellulose.

Synonyms:

• Methyl cellulose, international;
• E 461 (E-461), European code;
• cellulose methyl ether;
• methylcellulose, water-soluble;
• Cellulose-Methylether, German;
• methylcellulose, French.

Substance type

GOST 33310-2015 includes additive E 461 in the category of food thickeners.

Chemically, the substance is a synthetic polymer, an ether of natural cellulose and methanol.

The industrial method of obtaining the additive is based on high-pressure methylation of α-cellulose swollen in alkali with an ether solution of diazomethane or chloromethane, followed by purification and drying.

Properties

9 0185

9019 0

Index	Standard values ​​
Color	white, yellowish or grayish tint possible
Composition	cellulose polymer, empirical formula [C 6 H 7 O 2 (OH)x(OCH 3 )y]n, number of monomers ranges from 100 to 2000
Appearance	fine granules or fibrous powder
Odor	no
Solubility	good in cold water (up to 50ºC), acids, glycerol, esters; insoluble in mineral oils
Base content	25 to 33% methoxy groups and 5% hydroxyethyl groups
Taste	neutral
Density	1. 290-1.310 g/cm³
Other	Forms a reversible gel in hot water. At a temperature of 220-270 ° C, it melts with decomposition; the aqueous solution is stable at pH values ​​from 2 to 12; high light fastness; resistant to chemicals and temperature extremes

Packaging

Manufacturers package food additive E 461 in unstabilized polyethylene bags. As outer packaging use:

• winding drums;
• Multilayer paper bags;
• polypropylene yarn bags.

Application

Food additive E 461 has interesting properties that allow it to be used in various areas of human activity:

• completely dissolves in cold water to form a homogeneous viscous mass, effectively stabilizing any mixture. Viscosity depends on the concentration of the substance in the product;
• forms a gel at temperatures above 55º C, which breaks down with decreasing temperature. The property has found wide application in the production of durable and environmentally friendly wallpaper adhesives;
• aqueous solutions of methylcellulose are pseudoplastic. This allows them to be used in the manufacture of ketchups, sauces, as well as in the paint and varnish industry;
• has high adhesive properties: the additive is used in the production of building and finishing materials, added to minced meat to improve the binding of products.

The food industry uses the additive E 461 in small quantities: methylcellulose adversely affects the digestive tract.

The thickener is not included in the number of prohibited, in quantities from 0.1 to 10 g / kg it can be found in the composition of the following products: As a result, the yield of the finished product is significantly increased;

meat and sausage products: stabilizes and clarifies water-fat emulsions, protects the product from the formation of fatty smudges, increases product yield due to moisture binding.

The Codex Alimentarius permits the use of E 461 as a thickener and gelling agent in fish products, canned oranges and tangerines, reduced calorie spreads.

The additive is included in the list of approved products in Russia, the countries of the EAEU and the European Union, the USA, Great Britain, Australia, and China. The allowable rate has not been established.

Methylcellulose is widely used in the pharmaceutical industry.

Thickener E 461 is used as a base in degreased protective oil-in-water emulsions for the treatment of burns and wounds.

Cellulose methyl ether is an important component of eye drops (including for the treatment of glaucoma).

As an aid, additive E 461:

• increases the residence time of the drug in the diseased organ;
• reduces the likelihood of allergic reactions, burning and other side effects;
• promotes rapid penetration of the drug into the cornea.

Another area of ​​application of methylcellulose is the manufacture of drugs that improve intestinal motility. Taking more than 5 g of the substance causes a laxative effect. In Russia, an additive for the treatment of constipation is allowed only in combination with other drugs, but in some foreign countries (USA, UK) it acts as an independent medicine.

Benefit of a laxative to harm caused by side effects is below reasonable.

The cosmetics industry uses cellulose methyl ether as a thickener, emulsifier in low fat skin care creams, toothpastes, masks and hair mousses.

Effective bonding action, ability to form films on the surface, high adhesion made it possible to use methylcellulose in the construction industry . The granulated additive is included in the composition of dry building mixtures. A small amount of the substance (up to 0.7% of the total mass) is sufficient to improve elasticity, regulate viscosity, and obtain pseudoplastic frost-resistant solutions.

Additive E 461 is a component of water-based paints and adhesives. It is especially valuable that materials based on methylcellulose can be applied to any substrate.

Benefits and harms

Methylcellulose is not biologically active. The product is not a source of substances valuable for the body.

Once in the stomach, it is excreted naturally without being subjected to enzymatic metabolism. The substance is hypoallergenic, does not irritate mucous membranes and skin.

E 461 supplement cannot be considered completely safe: methylcellulose can provoke the development of dyskinesia. A complex violation of the intestines is manifested by long-term pain in the abdomen, impaired peristalsis. In a severe case, intestinal obstruction is possible.

Particular care should be taken by people suffering from gastrointestinal diseases: methylcellulose almost always causes an exacerbation of ailments.

Side effects have led to very limited use of E 461 in the food industry.

Beta cyclodextrin is a completely safe substance, it is excreted from the human body unchanged.

How does the food additive E402 affect the human body? Learn about it here.

Did you see the antioxidant E320 in your favorite product? Learn more about this substance from our article.

Main producers

Additive E 461 comes to the Russian market from abroad.

The largest manufacturer is the international concern Bayer , which unites more than 350 global companies (headquartered in Germany).

The demand of domestic producers for methylcellulose is met by German companies:

• IMCD Deutschland GmbH & Co. KG;
• Dow Wolf Cellulosics GmbH;
• Mikro-Technik GmbH & Co. KG;
• OXEA GmbH.

Chinese manufacturers try to compete by offering the chemical at a lower price:

• Shanghai Kaidu Industrial Development Co., Ltd.;
• Beijing Cheng Yi Chemical Co.