Multivitamins effect. Multivitamin Effects: Understanding Timespan and Safety Concerns
How long do multivitamins take to work. What are the potential side effects of multivitamins. When should you be concerned about taking multivitamins. How do multivitamins affect different age groups.
The Prevalence and Purpose of Multivitamin Supplementation
Multivitamins have become a staple in many households, with approximately one-third of adults in the United States incorporating them into their daily routines. The reasons for this widespread use are varied, but they generally revolve around a desire to enhance or maintain overall health, prevent nutrient deficiencies, or fill potential gaps in dietary intake.
While multivitamins are readily available without a prescription and are often perceived as safe, it’s crucial to understand that they are not entirely risk-free. This article delves into the potential concerns surrounding multivitamin use, exploring their effects, timespan, and when caution may be necessary.

Essential Nutrients and the Role of Multivitamins
The human body requires a minimum of 13 vitamins and 16 minerals to function optimally. Ideally, these nutrients should be obtained through a well-balanced diet. However, for individuals who struggle to meet their nutritional requirements through food alone, multivitamins can serve as a valuable alternative source.
Are all multivitamins created equal? Generally, multivitamins that provide up to 100% of the daily Dietary Reference Intakes (DRIs) are considered safe and unlikely to cause side effects when taken as directed. However, it’s important to note that individual responses can vary, and some people may experience mild side effects even with standard formulations.
Common Side Effects of Multivitamin Supplementation
While multivitamins are generally well-tolerated, some individuals may experience minor side effects, particularly when first starting supplementation. These common side effects include:
- Constipation
- Diarrhea
- Upset stomach
- Nausea
In most cases, these gastrointestinal symptoms are mild and transient, often subsiding as the body adjusts to the supplement. However, if these symptoms persist or worsen, it’s advisable to consult a healthcare provider for guidance.

Rare Side Effects and Potential Risks
While less common, some individuals may experience rarer side effects from multivitamin use, including:
- Headaches
- Nosebleeds
- Insomnia
- Gout
These side effects are typically infrequent, especially when the nutrient dosages in the multivitamin do not exceed the daily safe upper limit (UL). However, certain factors can increase the risk of experiencing these effects.
Can combining supplements increase the risk of side effects? Indeed, individuals who combine multivitamins with other dietary supplements or consume significant amounts of fortified foods may inadvertently exceed the UL for certain nutrients, potentially increasing their risk of adverse effects.
Understanding Fortified Foods
Fortified foods are products to which manufacturers have added nutrients during the production process. While these can be beneficial for addressing specific nutritional needs in the population, they can also contribute to excessive nutrient intake when combined with supplements.

Allergic Reactions and Severe Side Effects
Although extremely rare, some individuals may experience severe allergic reactions to certain components in multivitamins. Symptoms of a severe allergic reaction may include:
- Hives
- Difficulty breathing
- Swelling of the face, tongue, lips, or throat
If any of these symptoms occur after taking a multivitamin, it’s crucial to seek immediate emergency medical attention.
Multivitamin Effects in Infants and Children
The side effects of multivitamins in children are generally similar to those experienced by adults. However, children may be more susceptible to these effects at lower doses due to their smaller body size and developing systems.
Do children face a higher risk of nutrient overdose from multivitamins? Unfortunately, yes. Children who take multivitamins may have an increased risk of consuming excessively high levels of nutrients, which can lead to nutrient overdoses and, in severe cases, even death.
A recent study revealed that up to 65% of multivitamins marketed specifically for infants and children contain nutrient levels above the safe upper limits (UL) for children. This finding is particularly concerning for certain nutrients, including vitamin A, folic acid, and zinc.

The Danger of Iron Overdose in Children
Iron-containing multivitamins pose a particular risk to children who do not require iron supplementation. Iron overdose is considered a leading cause of poisoning in children 6 years old and under. To mitigate these risks, it’s essential to consult a healthcare provider before giving any multivitamin to a child.
Regulatory Considerations and Megadoses
While multivitamins providing nutrient levels within the DRI guidelines are generally considered safe, it’s important to note that the government does not regulate dietary supplements in the same way as medications. This regulatory gap can lead to potential discrepancies between the nutrient levels stated on the label and the actual content of the supplement.
Are all multivitamins accurately labeled? Unfortunately, there’s a risk that some multivitamins may contain higher levels of nutrients than their labels indicate. In some cases, nutrient levels may even reach or exceed the daily UL.
The Megadose Phenomenon
Some multivitamin formulations intentionally offer megadoses of certain nutrients, exceeding the UL recommendations. This approach capitalizes on the belief held by some consumers that higher nutrient intake correlates with better health outcomes. However, it’s crucial to understand that while megadoses of some nutrients may not be particularly harmful, extremely high doses of certain vitamins and minerals can have serious health consequences.

Nutrients of Concern: Understanding the Risks
Multivitamins typically contain three categories of nutrients, each with its own set of considerations:
1. Water-Soluble Vitamins
Water-soluble vitamins include the B-complex vitamins and vitamin C. These vitamins are generally considered safe, even at high doses, as excess amounts are typically excreted in urine. However, extremely high doses of certain water-soluble vitamins can still cause side effects.
For example, high doses of vitamin B6 may lead to nerve damage, while excessive vitamin C intake can cause diarrhea and increase the risk of kidney stones in susceptible individuals.
2. Fat-Soluble Vitamins
Fat-soluble vitamins (A, D, E, and K) are stored in the body’s fat tissues and can accumulate over time. This accumulation increases the risk of toxicity when consumed in excess. Some potential risks associated with high doses of fat-soluble vitamins include:
- Vitamin A: Liver damage, birth defects, and increased risk of osteoporosis
- Vitamin D: Elevated blood calcium levels, kidney stones, and heart problems
- Vitamin E: Increased risk of bleeding, especially in people taking blood thinners
3. Minerals
Minerals in multivitamins can also pose risks when consumed in excessive amounts. Some minerals of particular concern include:

- Iron: Can cause gastrointestinal distress and, in severe cases, organ damage
- Zinc: May interfere with copper absorption and impair immune function
- Selenium: Excessive intake can lead to hair loss, nail brittleness, and neurological problems
Understanding these potential risks underscores the importance of choosing multivitamins wisely and consulting with healthcare providers, especially for individuals with pre-existing health conditions or those taking medications.
Timespan of Multivitamin Effects
The timeframe in which multivitamins begin to exert their effects can vary depending on several factors, including an individual’s nutritional status, overall health, and the specific nutrients in question.
How quickly do multivitamins start working? For individuals with significant nutrient deficiencies, some effects may be noticeable within a few days to weeks of starting supplementation. These initial effects might include increased energy levels or improvements in mood.
However, for many people who are not severely deficient in any particular nutrient, the effects of multivitamin supplementation may be more subtle and take longer to manifest. Some potential benefits, such as improved immune function or reduced risk of chronic diseases, may only become apparent over months or even years of consistent use.

Factors Influencing Multivitamin Effectiveness
Several factors can influence how quickly and effectively multivitamins work:
- Individual nutrient status: People with pre-existing deficiencies may experience more rapid and noticeable effects.
- Absorption capacity: Factors such as age, digestive health, and medication use can affect nutrient absorption.
- Quality and formulation of the multivitamin: Higher-quality supplements with more bioavailable forms of nutrients may be more effective.
- Consistency of use: Regular, long-term use is typically necessary to experience the full benefits of multivitamin supplementation.
- Overall diet and lifestyle: A healthy diet and lifestyle can enhance the effects of multivitamin supplementation.
When to Be Concerned About Multivitamin Use
While multivitamins are generally safe for most people, there are certain situations where concern may be warranted:
1. Persistent Side Effects
If you experience ongoing gastrointestinal symptoms or other side effects that don’t resolve within a few weeks of starting a multivitamin, it’s advisable to consult a healthcare provider. These persistent symptoms could indicate an intolerance to a specific ingredient or an underlying health issue.

2. Interactions with Medications
Certain vitamins and minerals can interact with medications, potentially altering their effectiveness or increasing the risk of side effects. For example, vitamin K can interfere with blood-thinning medications, while iron and calcium supplements can affect the absorption of some antibiotics.
If you’re taking any medications, it’s crucial to discuss multivitamin use with your healthcare provider to avoid potential interactions.
3. Pre-existing Health Conditions
Some health conditions may necessitate caution when using multivitamins. For instance:
- Individuals with hemochromatosis should avoid iron-containing supplements.
- People with a history of kidney stones may need to be cautious with calcium and vitamin D supplementation.
- Those with certain types of cancer may need to avoid high-dose antioxidant supplements.
4. Pregnancy and Breastfeeding
While prenatal vitamins are often recommended during pregnancy and breastfeeding, it’s essential to use formulations specifically designed for these life stages. Regular multivitamins may not provide adequate amounts of crucial nutrients like folic acid or may contain ingredients that are not recommended during pregnancy.

5. Excessive Nutrient Intake
If you consume a diet rich in fortified foods or use multiple supplements in addition to a multivitamin, you may be at risk of exceeding safe upper limits for certain nutrients. This can be particularly concerning for fat-soluble vitamins and minerals that can accumulate in the body.
Regular blood tests and consultations with a healthcare provider can help ensure that your nutrient levels remain within a healthy range.
Optimizing Multivitamin Use for Maximum Benefit
To maximize the benefits of multivitamin supplementation while minimizing potential risks, consider the following strategies:
1. Choose a Reputable Brand
Look for multivitamins from well-established companies that adhere to Good Manufacturing Practices (GMP) and have their products tested by third-party organizations for quality and purity.
2. Tailor Your Supplement to Your Needs
Consider your age, gender, diet, and lifestyle when selecting a multivitamin. Specialized formulations are available for different life stages and nutritional needs.

3. Be Mindful of Dosages
Opt for multivitamins that provide close to 100% of the Daily Value (DV) for most nutrients, rather than megadose formulations. This approach helps reduce the risk of excessive intake.
4. Consider Your Diet
Assess your dietary intake of vitamins and minerals before starting a multivitamin regimen. If you consume a varied, nutrient-rich diet, you may not need a comprehensive multivitamin and could instead focus on specific nutrients you may be lacking.
5. Timing Matters
Some nutrients are better absorbed when taken with food, while others may be more effective on an empty stomach. Follow the recommendations on the product label or consult with a healthcare provider for optimal timing.
6. Regular Health Check-ups
Periodic health assessments, including blood tests to check nutrient levels, can help ensure that your multivitamin regimen is meeting your needs without causing any adverse effects.
By approaching multivitamin use thoughtfully and in consultation with healthcare professionals, you can harness the potential benefits of these supplements while minimizing the risk of side effects or nutrient imbalances.

The Future of Multivitamin Research and Personalization
As our understanding of nutrition and individual metabolic differences continues to evolve, the future of multivitamin supplementation is likely to become increasingly personalized. Emerging areas of research and development include:
1. Nutrigenomics
This field explores how individual genetic variations affect nutrient metabolism and requirements. Future multivitamins may be tailored based on genetic profiles to optimize effectiveness and minimize risks.
2. Microbiome Considerations
Research into the gut microbiome is revealing its significant role in nutrient absorption and overall health. Future multivitamin formulations may incorporate probiotics or prebiotics to enhance nutrient utilization.
3. Advanced Delivery Systems
Innovations in supplement technology may lead to more effective delivery systems that improve nutrient absorption and reduce side effects. This could include time-release formulations or novel encapsulation techniques.

4. Integration with Digital Health Tools
The rise of wearable devices and health tracking apps may allow for real-time monitoring of nutrient levels and more precise supplementation strategies.
As these advancements continue to unfold, it’s crucial for consumers to stay informed and work closely with healthcare providers to make the most of multivitamin supplementation. By understanding the potential benefits, risks, and individual factors that influence multivitamin effectiveness, we can make more informed decisions about our nutritional health and overall well-being.
Timespan and When to Be Concerned
Multivitamins are one of the most commonly used supplements in the United States — around one-third of adults currently take them (1).
People who take multivitamins often do so to improve or maintain their health, protect themselves against nutrient deficiencies, or simply make up for the odd nutrient gap in their diet (1).
You can purchase multivitamins without a prescription, and most people view them as safe, which might explain their popularity. Despite this, multivitamins are not risk-free.
This article discusses whether you should be concerned about taking multivitamins. It reviews the potential side effects of multivitamins and which ingredients may cause them.
Your body needs to consume at least 13 vitamins and 16 minerals regularly to function properly.
A well-balanced diet is the best way to obtain these nutrients. That said, multivitamins provide a good alternative source for those who are unable to meet their nutrient requirements through diet alone.
Multivitamins that provide up to 100% of the daily Dietary Reference Intakes (DRIs) are generally considered safe and often free of side effects, as long as you take them as directed.
Nonetheless, some people may still experience a few side effects when taking multivitamins. Some side effects are more common than others (2, 3).
Common side effects
Certain side effects are more likely to occur than others when you’re taking multivitamins. These include (2, 3):
- constipation
- diarrhea
- upset stomach
- nausea
These gut-related side effects are generally minor and often temporary. They tend to disappear as your body gets used to taking the multivitamin.
Nevertheless, contact your healthcare provider for further assistance if your symptoms persist.
Rare side effects
Rarer side effects of multivitamins include (2, 3):
- headaches
- nosebleeds
- insomnia
- gout
These typically occur very infrequently, especially if the dosage of nutrients in your multivitamin does not exceed the daily safe upper limit (UL).
However, people who combine multivitamins with other supplements or eat significant amounts of fortified foods may exceed the UL for certain nutrients. This may increase their risk of side effects (4).
Food companies sometimes add nutrients to foods during the manufacturing process. These are fortified foods.
Some people may also experience severe allergic reactions to certain multivitamins, although this is very rare.
If you notice hives, difficulty breathing, or swelling of the face, tongue, lips, or throat after taking a multivitamin, seek emergency medical help immediately.
Side effects in infants and children
Side effects in children are similar to those that adults may experience. However, children are likely to experience them at much lower doses than adults.
In other words, children who take multivitamins may have a higher risk of consuming extremely high levels of nutrients, which can lead to nutrient overdoses and even death in severe cases.
Companies market many multivitamins specifically for infants and children. However, a recent study suggests that up to 65% of them contain nutrient levels above the safe upper limits (UL) for children (5).
This may explain why experts report that children who consume multivitamins have a high risk of exceeding the UL, particularly for vitamin A, folic acid, and zinc (4).
Giving your child an iron-containing multivitamin when they don’t need it may also cause them to overdose on iron. Scientists consider this to be a lead cause of poisoning in children 6 years old and under (4).
To reduce the risk of side effects or toxic overdoses, make sure to consult your healthcare provider before giving your child a multivitamin.
Summary
Multivitamins are generally safe as long as they provide nutrient levels that fall within the DRI guidelines. Some people experience gut-related side effects when they first start taking a multivitamin, but these usually resolve quickly.
Other side effects are rare.
The National Institutes of Health asserts that multivitamins providing nutrient levels that fall close to their DRI shouldn’t cause serious side effects. However, it’s important to note that the government doesn’t regulate multivitamins in the same way as it does medications (4).
This means there’s a risk that a multivitamin could contain higher levels of nutrients than its label states. Nutrient levels in some multivitamins may sometimes even reach or exceed the daily UL.
Others offer megadoses of certain nutrients that purposefully exceed the UL recommendations, capitalizing on some people’s belief that the more nutrients you ingest, the better the health effects.
Megadoses of some nutrients may not be particularly harmful, but extremely high doses of certain nutrients can seriously harm your health (4).
Nutrients to watch out for
Multivitamins generally contain three categories of nutrients:
- Water-soluble vitamins.
These can dissolve in water and don’t usually accumulate in the body nor cause severe side effects if you take them in excess (e.g., B vitamins, vitamin C). - Fat-soluble vitamins. These dissolve in fat and accumulate in the body, reaching toxic levels and potentially causing havoc if you take them in excess (e.g., vitamins A, D, E, and K).
- Minerals. These are inorganic elements that can accumulate in the body and sometimes cause harmful effects if you take them in excess (e.g., iron, iodine, zinc, copper, and selenium).
Some of these cause more side effects at higher dosages than others. The sections below highlight the nutrients from each category that may be particularly harmful if you take them at high doses.
Water-soluble vitamins
Excess intakes of water-soluble vitamins don’t typically cause severe side effects, even when intakes are close to the UL.
This is because your body tends to flush out excess intakes of these vitamins through your urine.
Still, intakes that are several times over the UL may result in a variety of issues.
For instance, vitamin C intakes that are three times larger than the UL may cause cramps, diarrhea, nausea, vomiting, or migraines (6, 7).
Excess vitamin B3, also known as niacin, starting from intakes three times above the current UL may result in stomach pain, high blood pressure, vision problems, and liver damage (8).
Similarly, taking vitamin B6 at 10 times above the UL over the long term has been linked to skin lesions, light sensitivity, heartburn, and neurological problems (9).
Finally, excess intakes of vitamin B9, also known as folic acid, may weaken the immune system, cause neurological problems, and mask a severe vitamin B12 deficiency (10).
Fat-soluble vitamins
Multivitamins that offer large amounts of fat-soluble vitamins can be harmful, as excess levels of these vitamins can build up in the body.
For instance, excess intakes of vitamin A may cause headaches, liver damage, weaker bones, and birth defects (11).
Smokers and former smokers may especially benefit from avoiding multivitamins containing high amounts of vitamin A or beta carotene, which the body can convert into vitamin A. Getting too much of these nutrients may increase the risk of lung cancer (1, 4, 11).
Similarly, taking too much vitamin D, either due to manufacturing errors or taking an inappropriately high dosage, may result in nausea, vomiting, muscle weakness, cognitive problems, heart problems, kidney failure, and even death in severe cases (12).
Moreover, excess amounts of vitamin E may result in bleeding, diarrhea, weakness, blurred vision, and fertility problems (1, 13).
As for vitamin K, research has not found excessive intakes to cause too many problems. However, this vitamin can interact with various medications, including antibiotics and blood thinners.
People currently taking medications should let their healthcare provider know if they’re taking a multivitamin containing vitamin K (14).
Minerals
Like fat-soluble vitamins, minerals can accumulate in the body if you take them in excess, possibly causing harmful effects.
For instance, overly high intakes of certain minerals, such as iron, copper, magnesium, and zinc, can cause stomach upset, constipation, diarrhea, nausea, vomiting, stomach pain, and headaches (4, 15, 16, 17, 18).
Excess iron intake is particularly harmful because it may also cause liver problems.
For this reason, authorities advise adult men and postmenopausal women to avoid taking multivitamins that contain 18 mg of iron or more unless their healthcare provider advises them to do so (19).
Multivitamins containing high levels of iron, copper, and zinc may also prevent the body from absorbing other nutrients you consume (15, 16, 17).
Multivitamins containing too much iodine can cause thyroid problems. On the other hand, those with too much selenium may cause garlic-like breath, hair loss, brittle nails, or a metallic taste in the mouth (20, 21).
Selenium intakes above the UL may also cause severe neurological symptoms, kidney failure, and heart issues (21).
DRIs and ULs for each nutrient of concern
Most of the side effects mentioned in this article occur after a person consumes nutrient amounts that exceed the current upper levels (ULs).
Every nutrient has a UL at which scientists believe it becomes toxic. Exceeding a nutrient’s UL can lead to an overdose and severe side effects, such as liver damage and even death.
The following chart outlines both the DRI and UL for each nutrient of concern for adults.
Specific recommendations for infants and children vary widely based on their age. You can find more information in these exhaustive nutrient tables (22).
| DRI for adult men | DRI for adult women | UL | |
|---|---|---|---|
| Vitamin A | 900 mcg retinol activity equivalents (RAE) | 700 mcg RAE | 3,000 international units (IU) |
| Vitamin B3 (niacin) | 16 mg niacin equivalents (NE) | 14 mg NE | 35 mg* |
| Vitamin B6 (pyridoxine) | 1. 3 mg | 1.3 mg | 100 mg |
| Vitamin B9 (folate) | 400 mcg dietary folate equivalents (DFE) | 400 mcg DFE | 1,000 mcg* |
| Vitamin C | 90 mg | 75 mg | 2,000 mg |
| Vitamin D | 600 IU | 600 IU | 4,000 IU |
| Vitamin E | 15 mg | 15 mg | 1,000 mg* |
| Vitamin K | 120 mcg | 90 mcg | No UL established |
| Copper | 900 mcg | 900 mcg | 10,000 mcg |
| Iodine | 150 mcg | 150 mcg | 1,100 mcg |
| Iron | 10 mg | 18 mg | 45 mg |
| Magnesium | 420 mg | 320 mg | 350 mg* |
| Selenium | 55 mcg | 55 mcg | 400 mcg |
| Zinc | 11 mg | 8 mg | 40 mg |
*Applies only to synthetic forms from supplements, fortified foods, or a
combination of the two.
It’s important to note that there’s no DRI available for folic acid, the synthetic form of vitamin B9 that you can find in multivitamins.
The form of vitamin B9 in the table above is called folate, and you can get it from natural sources — not multivitamins.
However, studies have found that dosages of the synthetic folic acid of more than 1,000 mcg per day may be associated with a range of negative health consequences in several populations (23, 24, 25).
Currently, researchers don’t fully understand the effects and safety of long-term intakes of vitamin or mineral dosages that fall between the DRI and UL. Therefore, scientists need to do more research on this topic.
Until more is known, it’s likely safest to avoid supplements that offer nutrient levels that exceed their DRIs.
Summary
Consuming multivitamins that contain nutrient levels exceeding the daily UL may result in an array of side effects. Scientists need to conduct more research to evaluate the effects of nutrient intakes that fall between the DRI and UL.
Multivitamins may also become contaminated with harmful compounds, such as arsenic or lead (26, 27).
When you ingest these harmful compounds in large amounts or over a longer period of time, they may cause a variety of health issues, including physical, muscular, and neurological problems, as well as birth defects (26, 28).
It’s impossible to identify whether a multivitamin contains these harmful compounds by looking at its label alone.
However, some manufacturers opt to get their supplements verified by third-party labs, which can confirm whether they’re free of contaminants and that they truly contain what the label states.
Some examples of independent supplement testing companies include ConsumerLab, NSF International, and U.S. Pharmacopeia.
Summary
Multivitamins can become contaminated with harmful compounds, such as arsenic or lead. To minimize this risk, consider choosing multivitamins that a third-party lab has independently tested.
Depending on the nutrient and its dosage, some side effects may occur very quickly, while others may take a longer time to develop (11).
For instance, taking a very high dose of one or multiple nutrients may cause gut symptoms that generally develop shortly after taking the supplement (15, 16, 17).
However, more severe side effects may develop over time as excess amounts of nutrients or unwanted contaminants gradually accumulate in the body. These longer-term side effects may include birth defects and liver, heart, and cognitive issues (11, 20, 21, 27, 28).
If you think you’re experiencing any side effects, make sure to bring them up with your healthcare provider as promptly as possible.
Summary
The speed at which you may experience side effects depends on the type and dosage of nutrient you consumed. Make sure to discuss any side effects with your healthcare provider as soon as you notice them.
Multivitamins can be helpful for those who are unable to reach their daily nutrient needs through diet alone.
However, multivitamins cannot replace a balanced diet, and taking them in high amounts may result in side effects ranging from mild stomach upset to severe liver and heart problems.
Like many supplements, multivitamins are not strictly regulated and may contain much higher levels of nutrients than the label states. Depending on the nutrient, this will influence the speed and severity at which you may experience side effects.
You can minimize your risk by only taking multivitamins when you truly need them. Opt for ones that contain nutrient levels close to the current DRIs and have been tested by a third-party lab.
Is There Really Any Benefit to Multivitamins?
Half of all American adults—including 70 percent of those age 65 and older—take a multivitamin or another vitamin or mineral supplement regularly. The total price tag exceeds $12 billion per year—money that Johns Hopkins nutrition experts say might be better spent on nutrient-packed foods like fruit, vegetables, whole grains and low-fat dairy products.
In an editorial in the journal Annals of Internal Medicine titled “Enough Is Enough: Stop Wasting Money on Vitamin and Mineral Supplements,” Johns Hopkins researchers reviewed evidence about supplements, including three very recent studies:
- An analysis of research involving 450,000 people, which found that multivitamins did not reduce risk for heart disease or cancer.
- A study that tracked the mental functioning and multivitamin use of 5,947 men for 12 years found that multivitamins did not reduce risk for mental declines such as memory loss or slowed-down thinking.
- A study of 1,708 heart attack survivors who took a high-dose multivitamin or placebo for up to 55 months. Rates of later heart attacks, heart surgeries and deaths were similar in the two groups.
Will a Daily Vitamin Help Keep Your Heart Healthy?
youtube.com/embed/E1KgDBkM_Yo?rel=0&showinfo=0″ allowfullscreen=””>
Is a daily vitamin necessary? Get the answer from Johns Hopkins physician Edgar Miller III.
The Vitamin Verdict
The researchers concluded that multivitamins don’t reduce the risk for heart disease, cancer, cognitive decline (such as memory loss and slowed-down thinking) or an early death. They also noted that in prior studies, vitamin E and beta-carotene supplements appear to be harmful, especially at high doses.
“Pills are not a shortcut to better health and the prevention of chronic diseases,” says Larry Appel, M.D., director of the Johns Hopkins Welch Center for Prevention, Epidemiology and Clinical Research. “Other nutrition recommendations have much stronger evidence of benefits—eating a healthy diet, maintaining a healthy weight, and reducing the amount of saturated fat, trans fat, sodium and sugar you eat.”
The exception is supplemental folic acid for women of child-bearing potential, Appel says.
“Folic acid prevents neural tube defects in babies when women take it before and during early pregnancy. That’s why multivitamins are recommended for young women.” The Centers for Disease Control and Prevention recommends that all women of reproductive age get 400 micrograms of folic acid daily. The amount of iron in a multivitamin may also be beneficial for women of child-bearing potential, Appel adds.
“I don’t recommend other supplements,” Appel says. “If you follow a healthy diet, you can get all of the vitamins and minerals you need from food.”
What the Experts Do
Healthy Food Instead of Supplements
“I don’t take any supplements routinely,” says Larry Appel, M.D., director of the Johns Hopkins Welch Center for Prevention, Epidemiology and Clinical Research. “I try to eat three healthy meals a day to get the vitamins, minerals and other nutrients I need.
” How he does it:
- Plenty of produce. “I aim for two or more servings of fruits or vegetables at every meal,” he says. “I enjoy salads and have one for lunch or dinner several times a week.”
- Low-fat dairy and whole grains. “Low-fat or fat-free milk and yogurt provide calcium, magnesium, potassium and other nutrients,” he says. “I have cereal with milk for breakfast a few times a week. And I have yogurt sometimes too.”
- Protein. “At home we usually have fish or chicken for dinner. I am not a vegetarian; rather, I eat minimal meat,” Appel says. Some fish, such as salmon, are a good source of healthful omega-3 fatty acids.
Definitions
Whole grains: Grains such as whole wheat, brown rice and barley still have their fiber-rich outer shell, called the bran, and inner germ. It provides vitamins, minerals and good fats. Choosing whole grain side dishes, cereals, breads and more may lower the risk for heart disease, type 2 diabetes and cancer and improve digestion, too.
Saturated fat: A type of fat found in abundance in butter, whole milk, ice cream, full-fat cheese, fatty meats, poultry skin, and palm and coconut oils. Saturated fat raises levels of heart-threatening LDL cholesterol in your bloodstream. It can also interfere with your body’s ability to absorb blood sugar easily. Limiting saturated fat can help control your risk for heart disease.
Omega-3 fatty acids (oh-may-ga three fah-tee a-sids): Healthy polyunsaturated fats that the body uses to build brain-cell membranes. They’re considered essential fats because our body needs them but can’t make them on its own; we must take them in through food or supplements. A diet rich in omega-3s—found in fatty fish, like salmon, tuna and mackerel, as well as in walnuts, flaxseed and canola oil—and low in saturated fats may help protect against heart disease, stroke, cancer and inflammatory bowel disease.
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Half of American adults and 70% of those over 65 regularly take multivitamin and mineral supplements, spending about $12 billion a year on them.
It would be better to spend it on healthy foods that contain all the vitamins and minerals that a person needs in a natural form, such as vegetables and fruits, whole grains and low-fat dairy products, say Johns Hopkins University experts.
- Why vitamin supplements don’t work and can be deadly
- “Vitamin drips” in schools and hairdressers.
Why are they dangerous? - Scientists: multivitamins are not needed during pregnancy
Multivitamins (or multivitamins) are preparations containing several vitamins, sometimes together with trace elements, in one capsule.
In an editorial in the Annals of Internal Medicine entitled “Enough: Stop Throwing Money on Multivitamin and Mineral Supplements,” they reported on the results of three studies they conducted. Here are the main findings:
- Analysis of 450 thousand people shows that multivitamins do not reduce the risk of heart disease and cancer
- Follow-up of 5947 men over 12 years showed that they do not reduce the risk of cognitive and memory degradation
- Among 1708 people heart attack survivors, of whom one group took high doses of multivitamins for 55 months, and the other placebo, the number of repeated heart attacks, heart operations and deaths was about the same
Researchers have also found that vitamin E and beta-carotene supplements can be harmful, especially at high doses.
“Pills are not a shortcut to health and chronic disease prevention,” says Larry Appel, director of the Center for Prevention, Epidemiology and Clinical Research at Johns Hopkins University. and salt.”
The exception is folic acid supplements for women of childbearing age, he points out. “Folic acid prevents neural tube defects in babies if the mother takes it before and in early pregnancy. Therefore, a multivitamin is recommended for young women.”
The Center for Prevention, Epidemiology and Clinical Research advises all women of reproductive age to take 400 micrograms of folic acid daily. The iron found in multivitamins can also be good for them, adds Larry Appel.
“I don’t recommend anything else,” he says. “If you eat a healthy diet, you’ll get all the vitamins and minerals you need from food.”
M.D. diet
Image copyright, Getty Images
“I don’t take any supplements,” said Larry Appel.
for dinner”.
“Skim milk and yogurt contain calcium, magnesium, potassium, so I have whole grain porridge with milk for breakfast several times a week and often eat yogurt.”
“At home, we usually have fish or chicken for dinner, which contains the necessary proteins. I’m not a vegetarian, I just try to eat less meat. Some types of fish, such as salmon, are rich in healthy omega-3 fatty acids.”
Other advice and what Hopkins University scientists do not advise
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Whole Grains: Wheat, brown rice, and barley grains contain vitamins, minerals, and healthy fats. Whole-grain breads and cereals reduce the risk of heart disease, type 2 diabetes, and cancer, and improve digestion.
Omega-3 fatty acids: They are indispensable for the construction of brain cell membranes. The body does not produce them itself and must receive them from the environment. They are abundant in salmon, tuna, and mackerel, as well as nuts, flaxseed, and rapeseed oil. An appropriate diet reduces the risk of heart disease, stroke, cancer, and intestinal inflammation.
Saturated fat: Found in excess in butter, whole milk, full fat cheese, ice cream, fatty meats, poultry skins, palm oil, and coconut oil. Contribute to the accumulation of cholesterol in the vessels, adversely affect the absorption of sugar in the blood. Reducing the intake of saturated fat is a means of preventing cardiovascular disease.
However, it is possible that not everyone will agree with the recommendations of experts at Johns Hopkins University regarding the optimal diet. The views of some modern nutritionists and their conclusions about the benefits of a number of products, in particular, dairy, low-fat and cereals, differ from traditional recommendations.
Multivitamin complex – instructions for use, doses, side effects, reviews of the drug:
Analogs
All forms of release, dosages, registration certificates, drug manufacturers, drug characteristics
Product description Multivitamin complex (tablets) based on the official instructions, approved by the manufacturer in 2008
Approval date: 12/28/2008
Content
- Active substance
- ATX
- Pharmacological group
- Instruction
- Storage conditions
- Best before date
- Reviews
Active ingredient
Multivitamins (Multivitamins)
ATX
A11JC Vitamins, combinations
Pharmacological group
Vitamins and vitamin-like products
Manual
Pharma action.
Combined preparation, the action of which is due to the effects of the vitamins included in its composition.
Indications. Prevention of hypovitaminosis. Conditions accompanied by an increased need for vitamins: during the period of convalescence after serious illness, during periods of increased physical and mental stress, during pregnancy and lactation, malnutrition or unbalanced nutrition, reduction diets, to improve metabolism and general condition in the elderly and senile age (in part of complex therapy).
Contraindications. Hypersensitivity, hypervitaminosis A and D, children under 10 years of age.
Dosing regimen. Inside, after meals: adults – 1 tab. 3 times a day, children 11-14 years old – 2 tablets. per day. Tablets should be chewed and washed down with a small amount of liquid. The course of treatment is 20 days. If necessary, repeat the course after 2 months.
Side effects. Skin allergic reactions (urticaria).

Other side effects are rare.
These can dissolve in water and don’t usually accumulate in the body nor cause severe side effects if you take them in excess (e.g., B vitamins, vitamin C).
3 mg

Why are they dangerous?