What is nystatin cream used for in treating eczema. How does nystatin cream work against fungal skin infections. What are the potential side effects of using nystatin cream. How should nystatin cream be applied for optimal results.

Understanding Nystatin Cream and Its Antifungal Properties

Nystatin cream is a topical antifungal medication used to treat various fungal infections of the skin. It belongs to a class of drugs called polyene antifungals and works by killing sensitive fungi and yeasts. The cream is particularly effective against infections caused by Candida species, especially Candida albicans.

How does nystatin cream combat fungal infections? Nystatin binds to ergosterol, a component of fungal cell membranes, creating pores that lead to cell death. This mechanism allows nystatin to target fungi while generally sparing human cells, which lack ergosterol.

Primary Uses of Nystatin Cream

• Treating cutaneous candidiasis
• Managing yeast infections in skin folds
• Addressing fungal infections around nails
• Combating athlete’s foot caused by yeast

Is nystatin cream effective for all types of fungal infections? While highly effective against Candida species, nystatin cream is not suitable for all fungal infections. It is specifically designed for topical use and is not effective for systemic or internal fungal infections.

Nystatin Cream in the Management of Eczema Complications

While nystatin cream is not a primary treatment for eczema itself, it plays a crucial role in managing certain complications associated with the condition. Eczema can create an environment conducive to fungal growth, particularly in warm, moist areas of the body.

How does eczema increase the risk of fungal infections? Eczema compromises the skin barrier function, making it more susceptible to colonization by opportunistic fungi like Candida. Additionally, the scratching associated with eczema can create micro-abrasions, providing entry points for fungi.

Scenarios Where Nystatin Cream May Benefit Eczema Patients

1. Secondary fungal infections in eczematous areas
2. Intertrigo in skin folds affected by eczema
3. Prevention of fungal overgrowth during wet wrap therapy
4. Management of napkin (diaper) dermatitis with fungal component

Can nystatin cream be used alongside other eczema treatments? In many cases, nystatin cream can be used in conjunction with other eczema treatments, including topical corticosteroids. However, it’s essential to consult a healthcare provider for personalized advice on combining treatments.

Proper Application Techniques for Nystatin Cream

Correct application of nystatin cream is crucial for its effectiveness in treating fungal infections associated with eczema. Generally, the cream should be applied to clean, dry skin in a thin layer, covering the affected area and a small margin of surrounding healthy skin.

How often should nystatin cream be applied? Typically, nystatin cream is applied 2-4 times daily, depending on the severity of the infection and the healthcare provider’s instructions. Consistency in application is key to achieving optimal results.

Steps for Applying Nystatin Cream

1. Wash hands thoroughly before application
2. Clean and dry the affected area
3. Apply a thin layer of cream to the affected area
4. Gently massage the cream into the skin
5. Wash hands after application unless treating hand infections

Should nystatin cream be covered with a bandage? In most cases, nystatin cream does not need to be covered. However, for certain areas or to prevent the cream from rubbing off, a healthcare provider might recommend using a light, breathable covering.

Potential Side Effects and Precautions When Using Nystatin Cream

While nystatin cream is generally well-tolerated, some individuals may experience side effects. It’s important to be aware of potential adverse reactions and take necessary precautions when using the medication.

What are the most common side effects of nystatin cream? The most frequently reported side effects include mild skin irritation, redness, or itching at the application site. These symptoms are usually temporary and subside as treatment continues.

Less Common but Serious Side Effects

• Severe allergic reactions (rare)
• Persistent irritation or worsening of symptoms
• Development of new skin lesions
• Signs of systemic absorption (extremely rare)

When should you stop using nystatin cream and seek medical attention? If you experience severe irritation, signs of an allergic reaction (such as difficulty breathing, severe itching, or swelling), or if your symptoms worsen despite consistent use, discontinue the cream and consult your healthcare provider immediately.

Nystatin Cream in Pediatric Patients with Eczema

Nystatin cream can be a valuable tool in managing fungal complications in children with eczema. However, its use in pediatric patients requires special considerations and careful monitoring.

Is nystatin cream safe for use in infants and young children? Nystatin cream is generally considered safe for use in pediatric patients, including infants, when prescribed by a healthcare provider. However, the dosage and application frequency may differ from adult recommendations.

Special Considerations for Pediatric Use

• Use only as directed by a pediatrician
• Monitor for signs of irritation or allergic reactions
• Avoid application near the mouth to prevent accidental ingestion
• Consider potential interactions with other topical treatments

How should nystatin cream be applied in diaper areas? When treating diaper rash with a fungal component, apply a thin layer of nystatin cream at each diaper change, after gently cleaning and drying the area. Avoid using tight-fitting diapers, and allow for periods of diaper-free time when possible.

Combining Nystatin Cream with Other Eczema Treatments

In many cases, nystatin cream is used as part of a comprehensive treatment plan for eczema complicated by fungal infections. Understanding how to integrate nystatin cream with other eczema treatments is crucial for optimal management.

Can nystatin cream be used with topical corticosteroids? Yes, nystatin cream can often be used in conjunction with topical corticosteroids. In some cases, combination products containing both nystatin and a corticosteroid are available. However, it’s essential to follow your healthcare provider’s instructions regarding the order and timing of application.

Strategies for Combining Treatments

1. Apply treatments at different times of day
2. Allow each product to absorb before applying the next
3. Consider using combination products when appropriate
4. Monitor for any adverse interactions or increased side effects

How does nystatin cream interact with moisturizers and emollients? Moisturizers and emollients are crucial in eczema management. Generally, nystatin cream should be applied to clean, dry skin before moisturizers. Allow the nystatin cream to absorb for a few minutes before applying your regular moisturizer.

Alternatives to Nystatin Cream for Fungal Complications in Eczema

While nystatin cream is effective for many fungal infections associated with eczema, it’s not the only option available. Understanding alternative treatments can be beneficial, especially in cases where nystatin cream may not be suitable or effective.

What other antifungal treatments are available for eczema-related fungal infections? Other topical antifungals that may be used include azoles (e.g., clotrimazole, miconazole) and allylamines (e.g., terbinafine). In some cases, oral antifungal medications might be necessary for more severe or resistant infections.

Comparing Nystatin to Other Antifungal Treatments

• Azoles: Broader spectrum of activity, may be effective against some molds
• Allylamines: Particularly effective against dermatophytes
• Ciclopirox: Broad-spectrum antifungal with anti-inflammatory properties
• Natural remedies: Tea tree oil, garlic extract (limited scientific evidence)

How do you choose between nystatin and other antifungal treatments? The choice of antifungal treatment depends on various factors, including the specific fungal species involved, the location and extent of the infection, and individual patient factors. Your healthcare provider will consider these aspects when recommending the most appropriate treatment.

Long-Term Management and Prevention of Fungal Complications in Eczema

While nystatin cream can effectively treat acute fungal infections, long-term management strategies are essential for preventing recurrence and maintaining healthy skin in eczema patients prone to fungal complications.

How can you prevent fungal overgrowth in eczema-prone skin? Maintaining good skin hygiene, keeping skin folds dry, avoiding prolonged moisture exposure, and managing eczema flares promptly can help prevent fungal overgrowth. Additionally, using gentle, pH-balanced cleansers and moisturizers can support a healthy skin microbiome.

Strategies for Long-Term Management

1. Regular use of emollients to maintain skin barrier function
2. Prompt treatment of eczema flares to prevent skin barrier compromise
3. Use of antifungal powders in prone areas (e.g., skin folds) as preventive measure
4. Periodic use of antifungal shampoos or body washes
5. Dietary considerations to support overall skin health

Is maintenance therapy with nystatin cream recommended? In some cases, particularly for individuals with recurrent fungal infections, a healthcare provider might recommend periodic use of nystatin cream as a preventive measure. However, this approach should be carefully monitored to avoid developing resistance or unnecessary medication use.

Managing eczema complicated by fungal infections requires a comprehensive approach. While nystatin cream can be a valuable tool in treating acute fungal infections, it’s important to address the underlying eczema and implement strategies to prevent future complications. Regular follow-ups with a healthcare provider, consistent use of prescribed treatments, and attention to skin care routines are key components of successful long-term management. By understanding the role of nystatin cream and integrating it appropriately into a broader treatment plan, individuals with eczema can effectively manage fungal complications and maintain healthier skin.

Overview, uses, side effects, and more

Nystatin cream is an antifungal, antibiotic treatment for fungal infections of the skin. It can help resolve yeast infections but is only suitable for use on the skin.

Nystatin cream is a topical ointment, which means a person should only use it on their skin and nowhere else.

This article discusses the uses of nystatin cream, potential side effects, and more.

Nystatin treats fungal infections on the skin. In particular, nystatin treats yeast infections of the skin resulting from a type of fungus called Candida.

Candida lives in different parts of the body. Most of the time, it does not cause any issue. However, sometimes too much of the fungus grows, and an infection occurs.

The most common type of Candida that causes infections is Candida albicans.

While yeast infections are most common in the mouth, intestinal tract, and vagina, they can also occur on the skin. When these yeast-like infections develop on the skin, they often occur in warm, moist skin folds such as:

• the armpits
• under the breasts
• around nails
• on the feet, particularly between toes
• around the groin area

Learn more

Find out more about yeast infections.

• What does a yeast infection look like?
• What to know about breast yeast infection
• Diabetes and yeast infections (candidiasis)

When a yeast infection happens on the skin, it can cause uncomfortable symptoms in the affected area. Symptoms can include:

• itchy, red rash
• blisters and scales
• crusting of the skin or rash
• swelling
• pus

Nystatin cream treats yeast and yeast-like infections on the skin. It does not treat fungal infections that occur:

• in the eyes
• in the mouth or throat
• intravaginally
• systemically

Nystatin cream will treat the infection but will not relieve the itching, swelling, and other symptoms associated with the infection until the infection clears.

To treat swelling and itching, the National Institute for Health and Care Excellence (NICE) suggests using a corticosteroid cream in addition to antifungal cream.

Learn more

Find out more about fungal infections, skin infections, and other skin problems.

• What do skin infections look like?
• What you need to know about fungal infections
• What is causing my rash?

Most often, people who use nystatin cream will need to apply it generously to the affected area twice per day until the infection has cleared or as directed by a doctor.

A doctor can inform a person if they should use the cream more or less frequently.

If a person misses a dose, they should apply it as soon as possible unless it is nearly time to apply the next dose. In this case, they should skip the missed dose and continue as normal.

A person should not apply a large amount of cream at once to make up for the missed dose.

Anyone who uses nystatin cream should not let it get in their mouth or eyes and should not swallow it. Nystatin cream is also not suitable for use on or in the vagina.

If a person’s symptoms persist after the prescribed course has finished, they should consult a doctor again.

A person should not allow anyone else to use their prescribed nystatin cream and should keep it out of the reach of children, pets, and anyone else who could consume it.

Before using nystatin cream

Before using nystatin cream, a person should talk with a doctor if they have had a previous reaction to any of the components of the cream.

A person should also consult their doctor before use if they are pregnant or nursing.

People over 65 years should also discuss the use of nystatin cream with a doctor due to the potential for increased sensitivity to the medication.

Nystatin cream is generally safe to use on skin, with side effects occurring in less than 0.1% of people who use the cream.

However, some people using nystatin cream may notice side effects, including skin irritation or redness.

Serious allergic reactions to nystatin cream rarely occur.

Symptoms of a serious allergic reaction include:

• itching
• swelling of the face, tongue, or throat
• trouble breathing
• rash
• dizziness

If a person using the cream notices symptoms of an allergic reaction, they should stop using it and seek prompt medical attention.

Learn more about allergic reactions and rashes.

The body has limited absorption of topical nystatin cream and, therefore, should not interact with other medications a person is taking.

However, a person should always inform a doctor if they are taking any other medications, vitamins, drugs, or herbal supplements whenever they receive a new medication.

The following provides some answers to common questions about nystatin cream.

How long does nystatin cream take to work?

Symptoms of the fungal infection should improve within 24–72 hours after a person starts using nystatin cream.

However, a person should continue to use the cream the whole time the doctor prescribes, even if symptoms improve.

Can you use nystatin cream on babies?

Experts have found that the cream is safe and effective for children from birth.

However, a person should consult with a doctor before using the cream on a baby.

Does nystatin cream stop itching?

Nystatin cream itself does not stop a person’s skin from itching. However, as nystatin cream heals the fungal infection, the symptoms — including itching — will resolve.

To treat itching, NICE suggests using a corticosteroid cream in addition to antifungal cream.

Nystatin cream is an antifungal medication that treats yeast and yeast-like infections on the skin.

A person should only use the medication on their skin and keep it out of their mouth, eyes, and vagina.

The medication is generally safe and effective. A person should follow their doctor’s instructions for taking the medication and consult a doctor if they experience any side effects.

Side effects are rare and may include itching, redness, and swelling of the face, tongue, or mouth.

Overview, uses, side effects, and more

Nystatin cream is an antifungal, antibiotic treatment for fungal infections of the skin. It can help resolve yeast infections but is only suitable for use on the skin.

Nystatin cream is a topical ointment, which means a person should only use it on their skin and nowhere else.

This article discusses the uses of nystatin cream, potential side effects, and more.

Nystatin treats fungal infections on the skin. In particular, nystatin treats yeast infections of the skin resulting from a type of fungus called Candida.

Candida lives in different parts of the body. Most of the time, it does not cause any issue. However, sometimes too much of the fungus grows, and an infection occurs.

The most common type of Candida that causes infections is Candida albicans.

While yeast infections are most common in the mouth, intestinal tract, and vagina, they can also occur on the skin. When these yeast-like infections develop on the skin, they often occur in warm, moist skin folds such as:

• the armpits
• under the breasts
• around nails
• on the feet, particularly between toes
• around the groin area

Learn more

Find out more about yeast infections.

• What does a yeast infection look like?
• What to know about breast yeast infection
• Diabetes and yeast infections (candidiasis)

When a yeast infection happens on the skin, it can cause uncomfortable symptoms in the affected area. Symptoms can include:

• itchy, red rash
• blisters and scales
• crusting of the skin or rash
• swelling
• pus

Nystatin cream treats yeast and yeast-like infections on the skin. It does not treat fungal infections that occur:

• in the eyes
• in the mouth or throat
• intravaginally
• systemically

Nystatin cream will treat the infection but will not relieve the itching, swelling, and other symptoms associated with the infection until the infection clears.

To treat swelling and itching, the National Institute for Health and Care Excellence (NICE) suggests using a corticosteroid cream in addition to antifungal cream.

Learn more

Find out more about fungal infections, skin infections, and other skin problems.

• What do skin infections look like?
• What you need to know about fungal infections
• What is causing my rash?

Most often, people who use nystatin cream will need to apply it generously to the affected area twice per day until the infection has cleared or as directed by a doctor.

A doctor can inform a person if they should use the cream more or less frequently.

If a person misses a dose, they should apply it as soon as possible unless it is nearly time to apply the next dose. In this case, they should skip the missed dose and continue as normal.

A person should not apply a large amount of cream at once to make up for the missed dose.

Anyone who uses nystatin cream should not let it get in their mouth or eyes and should not swallow it. Nystatin cream is also not suitable for use on or in the vagina.

If a person’s symptoms persist after the prescribed course has finished, they should consult a doctor again.

A person should not allow anyone else to use their prescribed nystatin cream and should keep it out of the reach of children, pets, and anyone else who could consume it.

Before using nystatin cream

Before using nystatin cream, a person should talk with a doctor if they have had a previous reaction to any of the components of the cream.

A person should also consult their doctor before use if they are pregnant or nursing.

People over 65 years should also discuss the use of nystatin cream with a doctor due to the potential for increased sensitivity to the medication.

Nystatin cream is generally safe to use on skin, with side effects occurring in less than 0.1% of people who use the cream.

However, some people using nystatin cream may notice side effects, including skin irritation or redness.

Serious allergic reactions to nystatin cream rarely occur.

Symptoms of a serious allergic reaction include:

• itching
• swelling of the face, tongue, or throat
• trouble breathing
• rash
• dizziness

If a person using the cream notices symptoms of an allergic reaction, they should stop using it and seek prompt medical attention.

Learn more about allergic reactions and rashes.

The body has limited absorption of topical nystatin cream and, therefore, should not interact with other medications a person is taking.

However, a person should always inform a doctor if they are taking any other medications, vitamins, drugs, or herbal supplements whenever they receive a new medication.

The following provides some answers to common questions about nystatin cream.

How long does nystatin cream take to work?

Symptoms of the fungal infection should improve within 24–72 hours after a person starts using nystatin cream.

However, a person should continue to use the cream the whole time the doctor prescribes, even if symptoms improve.

Can you use nystatin cream on babies?

Experts have found that the cream is safe and effective for children from birth.

However, a person should consult with a doctor before using the cream on a baby.

Does nystatin cream stop itching?

Nystatin cream itself does not stop a person’s skin from itching. However, as nystatin cream heals the fungal infection, the symptoms — including itching — will resolve.

To treat itching, NICE suggests using a corticosteroid cream in addition to antifungal cream.

Nystatin cream is an antifungal medication that treats yeast and yeast-like infections on the skin.

A person should only use the medication on their skin and keep it out of their mouth, eyes, and vagina.

The medication is generally safe and effective. A person should follow their doctor’s instructions for taking the medication and consult a doctor if they experience any side effects.

Side effects are rare and may include itching, redness, and swelling of the face, tongue, or mouth.

Antifungal ointments and creams: types, effectiveness

Where can I buy?

Encyclopedia

Fungus

Skin fungus (mycosis) are diseases caused by pathogenic fungi, as well as fungi that are part of the normal microflora of human skin, but under certain conditions, can cause a rash and other unpleasant symptoms.

The author of the article

Moshkova Elena Mikhailovna

Dermatovenereologist, head of the KDO for the provision of paid services, St. Petersburg State Budgetary Institution of Health “City Dermatovenerologic Dispensary”, St. Petersburg.

Audio version of the page:

What is a fungus

Various rashes can occur periodically on the skin. As a rule, it is difficult to make a diagnosis on your own, since many skin diseases are similar to each other.

However, a rash in the interdigital spaces of the feet and a change in the color and structure of the nail plates should alert a person, since this may indicate a possible fungal nature of these phenomena.

Which parts of the body are affected by the fungus

Fungal infections of the skin can appear on different parts of the body. Be both an independent disease and a complication of other skin diseases (eczema, diaper rash, inverse psoriasis, atopic dermatitis).

Each pathogen of mycosis has favorite places for parasitizing on human skin.

For example, yeast-like fungi of the genus Malassezia (Malassesia) live on the skin of all people, inhabiting areas rich in sebaceous glands : skin of the scalp, face, behind the ear folds, chest and back. Predisposing factors (non-observance of personal hygiene, malnutrition, environmental pollution, hormonal changes) can provoke a pathological process – seborrheic dermatitis. As a result, redness of the skin, peeling, itching appears. The pathological process can even affect the eyelids. Crusts appear along the ciliary edge, eyelashes can be damaged. Doctors call this condition seborrheic blepharitis. By the way, dandruff is also a manifestation of seborrheic dermatitis.

Mushrooms of the genus Malassezia are also responsible for the occurrence of pityriasis versicolor (pityriasis). It should be recalled that neither seborrheic dermatitis nor versicolor are non-contagious skin diseases. But at the same time delivering serious aesthetic problems.

Patients with onychomycosis (nail fungus) experience no less discomfort and shyness. Changes in the color and structure of the nail can only be masked in the initial stages of the disease. Without treatment, even a single affected nail plate, the fungus can spread to other nails. Enough often nail fungus is combined with mycosis of the skin of the feet .

In the folds of the skin, especially with excessive sweating and diaper rash, you can see signs of skin candidiasis (caused by fungi of the genus Candida): redness and a whitish coating. The same fungi multiply on the mucous membrane of the genital organs and cause thrush in women, as well as candidal balanoposthitis and balanitis in men (rashes, burning and itching in the area of ​​the glans penis and foreskin).

A separate group consists of extremely contagious fungal infections: microsporia (ringworm) and trichophytosis. The causative agents of these diseases can affect both smooth skin and the scalp. With microsporia, the hair breaks off at a height of 5-6 mm from the surface of the scalp, and with trichophytosis – at a distance of 2-3 mm. On the skin of the body, both of these diseases are manifested by spots with peeling, nodules and small bubbles. Only a doctor can accurately diagnose. To do this, it is necessary to conduct an additional examination for the presence of mycelium of the fungus in the scraping, to conduct an examination in the Wood’s lamp. It is possible to determine the type of fungus by sowing on nutrient media.
In most cases, skin mycoses respond well to external antifungal agents.

External agents include:

• Special varnishes (for the treatment of onychomycosis)
• Sprays
• Shampoos
• Solutions
• Creams and ointments

Traditionally, in the treatment of mycosis of the skin, the form of ointment or cream is more often chosen.

Mechanism of action of an antifungal ointment or cream

Antifungal creams and ointments with various active ingredients that have a therapeutic effect are on the pharmaceutical market. Thus, antifungal drugs are selected based on a specific type of mycosis.

There are different active substances with antifungal effect: some have fungistatic effect (stop the growth and reproduction of fungi, reducing their numbers), others – fungicidal (cause the death of pathogens of fungal infection). For example, the modern drug sertaconazole has three actions at the same time ¹⁸ : fungicidal , fungistatic and blocking the transition of fungi into a pathogenic form (only for fungi of the genus Candida).

In addition, a number of studies have demonstrated a high sensitivity of fungi to sertaconazole compared to other azole antifungals ¹⁹ . One explanation for this is that sertaconazole is a more modern drug from the azole group, which may be associated with fewer cases of resistance or addiction of fungi to this therapy.

How to choose an effective antifungal cream

The first step is to confirm the diagnosis of athlete’s foot. This will help consult a dermatologist and additional examinations (scraping for the mycelium of the fungus, examination in the Wood’s lamp, microbiological (cultural) study with the definition of the type of fungus). Moreover, the doctor will determine the severity of the skin process and prescribe therapy, taking into account the indications and contraindications for a particular active substance.

In the treatment of mycoses, the main criteria are the efficacy and safety of antimycotic drugs. Sertaconazole is a drug with a high safety and efficacy profile in the treatment of mycoses. Due to the property of lipophilicity (the ability to dissolve in fatty structures), a good penetration of the cream based on sertaconazole into the skin and its long-term triple antifungal effect are ensured.

Due to the special chemical structure (sertaconazole consists of derivatives of two active molecules – imidazole and benzothiophene), a wide antimicrobial spectrum of the drug against pathogenic fungi (Candida albicans, C. Tropicalis, C. Spp., Pityrosporum orbiculare), dermatophytes (Trichophyton and Microsporum) is explained ) and pathogens of infections of the skin and mucous membranes (gram-positive strains of staphylo- and streptococci) ¹⁰ .

Instruction

Zalain ^® Cream for the treatment of fungal infections

Zalain ^® Cream 2% (active ingredient sertaconazole) is used in the treatment of various fungal processes on the skin of the body, hands, feet, including in the treatment of pityriasis versicolor, seborrheic dermatitis, candidiasis and especially contagious fungal infections: microsporia and trichophytosis. Allowed to use Zalain ^® cream 2% for face and intimate area ¹ .

When using Zalain ^® cream, recovery can be achieved faster than with other drugs (compared to clotrimazole) ⁹ , antipruritic and anti-inflammatory ⁸ .

How to use Zalain

^® Cream?

When sertaconazole is applied topically for 14 days, the components of the drug are not detected in the blood and urine, which indicates a high safety profile of the drug ³ . Therefore, dermatologists can recommend Zalain ^® Cream 2% even to pregnant women, but taking into account that the benefit to the mother outweighs the risk to the fetus, and also taking into account various factors ⁴ .

Has a triple effect: antifungal, antipruritic, anti-inflammatory

Used 1-2 times a day

Where to buy Zalain ^® Cream for the treatment of fungal infections

or

Find the nearest pharmacy

Prevention of fungal diseases

The fundamental rule in the prevention of fungal diseases is the observance of personal hygiene :

Use individual bath and manicure supplies, combs

Do not lean with a naked body against the surfaces of the jumps in common areas, including SPA zones and SPA zones and SPA zones and SPA zones and SPA zones fitness centers

After water procedures, be sure to dry the interdigital spaces

Do not walk barefoot in the bath, swimming pool, sauna

Seek a doctor in a timely manner in case of any skin problems

Choose clothes and shoes according to the season from high-quality materials, avoid excessive sweating

Frequently Asked Questions

Can thrush be treated with Zalain® cream?

Answer: Zalain ^® cream 2% can be prescribed for women with candidal vulvitis (inflammation of the female external genitalia), as well as for men for the treatment of superficial candidiasis of the male genital organs ⁵ .

Thrush, or vulvovaginal candidiasis, is caused by yeast-like fungi of the genus Candida. To treat this disease, antifungal drugs are prescribed. However, given the localization of the process, it is necessary to choose Zalain ^® Vaginal suppositories (suppositories) 300 mg. For treatment a single application of drug is sufficient. Due to the property of lipophilicity (the ability to dissolve in fatty structures), the agent has a long-term effect (7 days) on the vaginal mucosa. If necessary, therapy can be repeated after 1 week ⁶ .

To prevent the development of thrush, as well as during the treatment period, it is advisable to use special products for intimate hygiene. Unlike most cleansers on the pharmaceutical market, Zalagel ^® Intim has a slightly alkaline pH of 8-9, which is harmful to fungi of the genus Candida (causative agents of thrush). And the tea tree oil included in its composition has antifungal ⁷ , antibacterial ⁸ , antiprotozoal ⁹ (detrimental to protozoan unicellular microorganisms), antiviral ¹⁰ action, relieves itching ¹¹ .

Why do doctors sometimes prescribe hormonal creams for fungal infections?

Answer: The specialist makes appointments based on tests, symptoms and individual characteristics. Due to severe inflammation, in order to reduce soreness and itching in the shortest possible time, the doctor may prescribe drugs from this group. But in this case, in the prescribed remedy, along with an anti-inflammatory hormonal substance, an antimycotic is usually present. After removing the severity of the manifestations of a fungal infection, treatment is continued only with an antifungal drug for external use. Cream Zalain ^® based on sertaconazole has an anti-inflammatory effect and has a pronounced antipruritic effect.

Can fungal infections develop resistance to antifungal creams?

Answer: The problem of resistance (resistance) of pathogens of mycoses to antifungal creams today creates a serious problem for achieving positive results of treatment. Therefore, the question of choosing a new generation drug is acute. Cream containing sertaconazole (Zalain ^® cream 2%), due to its pronounced fungicidal action and good penetration into the skin, ⁹ does not cause the development of resistance.

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16. Astani A, Reichling J, Schnitzler P. Comparative study on the antiviral activity of selected monoterpenes derived from essential oils. Python Res 2009; 24(5):673-9.
17. Bassett, I. B., D. L. Pannowitz, and R. S. Barnetson. 1990. A comparative study of tea-tree oil versus benzoylperoxide in the treatment of acne. Med. J. Aust. 153:455-458.
18. Carrillo-Muñoz AJ, Tur-Tur C, Giusiano G, Marcos-Arias C, Eraso E, Jauregizar N, Quindós G. Sertaconazole: an antifungal agent for the topical treatment of superficial candidiasis. Expert Rev Anti Infect Ther. 2013 Apr;11(4):347-58. doi: 10.1586/eri.13.17. PMID: 23566144.
19. Carrillo-Munoz AJ, Guglietta A, Palacin C, et al. In vitro antifungal activity of sertaconazole compared with nine other drugs against 250 clinical isolates of dermatophytes and Scopulariopsis brevicaulis. Chemotherapy 2004 Dec; 50(6):308-13

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Dermatological preparations in Tashkent | XMED.UZ

MR MENOVAZIN solution 50 ml

• Producer country:

  Uzbekistan

• Active substance:

  –

• Category:

  Dermatological

MR NISTATIN ointment 10g 02 Uzbekistan

ADVANTAN 20.0 emulsion 0.1%

• Country of origin:

  Italy

• Active ingredient:

  Methylprednisolone aceponate

• Category:

  Dermatological

ADVANTAN cream 15g 0.1%

• Producer country:

  Italy 9 0003

• Active substance:

  Methylprednisolone aceponate

• Category:

  Dermatological

ADVANTAN cream 20g 0.

1%

• Country of origin:

  Italy 056

  Active ingredient:

  Methylprednisolone aceponate

• Category:

  Dermatological

ADVANTAN ointment 15g 0.1% from LEO Pharma Manufacturing S.r.L.

• Country of origin:

  Italy

• Active substance:

  Methylprednisolone aceponate

• Category:

  Dermatological

ADVANTAN emulsion 057

ACIDERM cream 10g

• Producer country:

  India 057

• Active substance:

  Gentamycin, Beclomethasone, Clotrimazole

• Category:

  Dermatological

AKNEL gel 10g

• Country of manufacture:

  India

• Active substance:

  Aloe extract, Asian centella extract, Madder cordifolia extract, Indian Azadirachta extract, Tulsi extract

• Category:

  Dermatological

ACNESTOP cream 30g 200mg/g

• Producer country:

  Ukraine

• Active ingredient:

  Azelaic acid

• Category:

  Dermatological

AKNEFAST solution 20 ml 10mg/ml

• Country of origin:

  China

• Active substance:

  Metronidazole, Clindamycin

• Category:

  Dermatological

AKNOTIN 10 capsules 10mg N29

• Producer country:

  Thailand

• Active substance:

  –

• Category:

  Dermatological

AKRIDERM GENTA cream 15g from Akrikhin Chemical and Pharmaceutical Plant OJSC

• Country of origin:

  Russia

• Active ingredient:

  Gentamycin, Betamethasone
  Akrikhin

• Category:

  Dermatological Russia

• Active ingredient:

  Gentamycin, Betamethasone

• Category:

  Dermatological

AKRIDERM GENTA cream 30 g manufacturer:

Russia

AKRIDERM GENTA ointment 15g

• Producer country:

  Russia

• Active ingredient:

  Gentamycin, Betamethasone

• Category:

  Dermatological

AKRIDERM GENTA ointment 30g

• Producer country:

  Russia 9 0003

• Active ingredient:

  Gentamycin, Betamethasone

• Category:

  Dermatological

AKRYDERM GK cream 15g 3

AKRIDERM GK ointment 15g 03

AKRYDERM cream 15g 0.

05%

• Country of manufacture:

  Russia

• Active substance:

  Betamethasone

• Category:

  Dermatological

Akriderm SK

• Country of manufacture:

  –

  9005 7

• Active substance:

  Salicylic acid, Betamethasone

• Category:

  Dermatological

AKRIDERM SK ointment 15g 03

AKRYDERM SK ointment 30g

• Country of manufacture:

  Russia

• Active ingredient:

  Salicylic acid, Betamethasone

• Category:

  Dermatological

ACRYSIL cream 10g 1%

• Producer country:

  India 9000 3

• Active ingredient:

  Terbinafine

• Category:

  Dermatological

AXEL CLOBETAZOL ointment 15g 0.

05%

• Producer country:

  90 002 Malaysia

• Active substance:

  Clobetasol

• Category:

  Dermatological

ALOPEXI solution 60 ml 5%

• Country of manufacture:

  France

• Active substance:

  –

• Category:

  Dermatological

ARKALENE ointment 30g 20mg+12.5mg

• Producer country:

  Poland

• Active substance:

  –

• Category:

  Dermatological

• Country of manufacture:

  Ukraine

• Active substance:

  Decamethoxin

• Category:

  Dermatological

AUROBIN ointment 20 g 03

ACYCLOVIR AKRIKHIN ointment 10g 5%

• Country of origin:

  Russia substance:

  Aciclovir

• Category:

  Dermatological

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New medicines

LOKOID KRELO emulsion 30g 0. 1% from Temmler Italia S.r.l

SEDALGIN NEO tablets N19 9 0003

ACC 600 HOT DRINK powder 600mg N5

LIDOCAINE eye drops 5 ml 2%

HUMALOG solution 3 ml 100 IU/ml N4

GLYCERIN 1.24 rectal suppositories N10 from Tula Pharmaceutical Factory

KETOROL 0.01 tablets N19

BROMHEXIN GR INDEX syrup 100 ml 4mg/5 ml

OMIZOL capsules 20mg N9

TERALIGEN VALENTA tablets 5mg N99

PLAVIX tablets 75mg N27

RIBOXIN injection solution 5ml 2% N10 from Novopharma plus,

LIOTON 1000 gel 30g

LOKOYD LIPOCREAM cream 30g 0.1 % of Temmler Italia S.r.l.

ISONIAZID syrup

SERVALOS granules 2g N27

PANCREOZIS 10000 capsules 10000mU N19

X PILES tablets N59 uzi 500 ml 6%

RESTATOR tablets 40mg N29

LOKOYD KRELO emulsion 30g 0.1% Temmler Italia S.r.L

SEDALGIN NEO tablets N19

ACC 600 HOT DRINK powder 6 00mg N5

LIDOCAINE eye drops 5 ml 2%

HUMALOG solution 3 ml 100 IU/ml N4

GLYCERIN 1.