Can you combine Pepto-Bismol and alcohol safely. What are the potential risks of mixing Pepto-Bismol with alcohol. How does Pepto-Bismol work to relieve stomach issues. What are alternative remedies for hangover symptoms.

Understanding Pepto-Bismol: Composition and Mechanism of Action

Pepto-Bismol, a widely recognized over-the-counter medication, is renowned for its distinctive pink color and efficacy in treating various gastrointestinal issues. The active ingredient in Pepto-Bismol is bismuth subsalicylate, a compound that possesses multiple beneficial properties for digestive health.

How does Pepto-Bismol work to alleviate stomach discomfort? The mechanism of action is multifaceted:

• Anti-inflammatory effects: Bismuth subsalicylate reduces irritation in the gastrointestinal tract.
• Protective coating: It forms a barrier on the stomach lining, shielding it from irritants like stomach acid.
• Antimicrobial properties: Pepto-Bismol can combat certain bacterial infections, including H. pylori.

These combined actions make Pepto-Bismol effective in treating symptoms such as upset stomach, diarrhea, and indigestion. However, its interaction with alcohol raises important considerations for consumers.

The Effects of Alcohol on the Digestive System

Alcohol consumption can have significant impacts on the digestive system, particularly when consumed in excess. Understanding these effects is crucial when considering the use of medications like Pepto-Bismol in conjunction with alcohol.

What happens to your stomach when you drink alcohol? Alcohol can irritate the stomach lining, leading to a condition known as gastritis. This irritation can manifest in several symptoms:

• Bloating and discomfort
• Diarrhea
• Nausea and vomiting
• Upper abdominal pain
• Food regurgitation

While occasional alcohol-induced gastritis may not be severe, chronic alcohol abuse can lead to more serious complications. These include stomach ulcers and gastrointestinal bleeding, which can have long-term health consequences.

Potential Interactions Between Pepto-Bismol and Alcohol

The combination of Pepto-Bismol and alcohol is a topic of concern for many healthcare professionals. While there is limited recent research on this specific interaction, several theoretical risks have been identified.

Why should you be cautious about mixing Pepto-Bismol and alcohol? The primary concerns include:

1. Liver metabolism interference: Both substances are processed by the liver, potentially leading to slower metabolism of each.
2. Extended presence in the body: This slower metabolism may result in both Pepto-Bismol and alcohol remaining in the system longer than usual.
3. Increased risk of gastrointestinal bleeding: Particularly in individuals with existing ulcers or sensitive stomach linings.
4. Potential liver strain: The liver may be overworked trying to process both substances simultaneously.

It’s important to note that while these risks are theoretical, the lack of extensive modern studies on the safety of this combination leads many medical professionals to advise against it.

Historical Studies on Pepto-Bismol and Alcohol Interaction

While current medical advice generally cautions against combining Pepto-Bismol and alcohol, it’s worth examining some historical studies that have explored this interaction. These studies, primarily from the 1990s, provide an interesting perspective on the topic.

One notable study, published in the Journal of International Medical Research in 1990, involved 132 volunteers who consumed alcohol to excess and were then given either Pepto-Bismol or a placebo. The results of this study were intriguing:

• No significant side effects were reported from the combination of Pepto-Bismol and alcohol.
• Participants who took Pepto-Bismol reported better symptom relief compared to those who received the placebo.

However, it’s crucial to approach these findings with caution. The study is over three decades old, and medical understanding and research methodologies have advanced significantly since then. Moreover, this is one of the few studies that directly examined the interaction between Pepto-Bismol and alcohol, leaving a gap in more recent, comprehensive research on the topic.

Recognizing the Signs of Gastrointestinal Bleeding

If you do decide to use Pepto-Bismol while drinking or shortly after alcohol consumption, it’s crucial to be aware of potential signs of gastrointestinal bleeding. This awareness can help you identify any serious complications that may arise.

What should you look out for if you’ve combined Pepto-Bismol and alcohol? Key indicators of gastrointestinal bleeding include:

• Bright red blood in the stool
• Dark, tarry stools (melena)
• Abdominal pain or cramping
• Weakness or dizziness
• Shortness of breath

It’s important to note that Pepto-Bismol can naturally turn stools black, which doesn’t necessarily indicate bleeding. However, if you experience any of the above symptoms, especially in combination with severe abdominal pain or dizziness, it’s crucial to seek medical attention immediately.

Differentiating Between Normal Pepto-Bismol Effects and Bleeding

How can you tell if black stools are from Pepto-Bismol or potential bleeding? Here are some key differences:

• Pepto-Bismol effect: Stools are typically dark but not tarry; no other symptoms present.
• Potential bleeding: Stools are very dark and sticky; often accompanied by other symptoms like abdominal pain or dizziness.

When in doubt, it’s always safest to consult a healthcare professional for proper evaluation.

Safe Alternatives for Hangover Relief

Given the potential risks associated with combining Pepto-Bismol and alcohol, it’s wise to consider safer alternatives for managing hangover symptoms. While there’s no scientifically proven cure for hangovers, several strategies can help alleviate discomfort.

What are some safe methods to manage hangover symptoms? Consider the following approaches:

1. Hydration: Drink plenty of water or electrolyte-rich beverages to combat dehydration.
2. Rest: Allow your body time to recover by getting adequate sleep.
3. Gentle nutrition: Consume easily digestible foods like bananas, toast, or broth.
4. Over-the-counter pain relievers: Use with caution and as directed, avoiding those containing acetaminophen if you’ve consumed alcohol recently.
5. Time: Remember that the most effective cure for a hangover is simply allowing your body time to process the alcohol.

It’s important to note that while these methods can help manage symptoms, they don’t accelerate the body’s process of metabolizing alcohol. The only truly effective way to avoid a hangover is to drink in moderation or abstain from alcohol altogether.

Myths About Hangover Cures

Many popular hangover remedies lack scientific backing. Some common myths include:

• “Hair of the dog” (drinking more alcohol): This only delays the inevitable hangover.
• Greasy food: While it might be satisfying, it doesn’t specifically treat hangover symptoms.
• Coffee: While it may increase alertness, it can also contribute to dehydration.

Understanding these myths can help you focus on more effective and healthier ways to manage hangover symptoms.

Long-Term Health Considerations of Alcohol Consumption

While the immediate effects of alcohol, such as hangovers, are often the primary concern for many drinkers, it’s crucial to consider the long-term health implications of regular alcohol consumption. Understanding these risks can provide valuable perspective on overall health and wellness.

What are the potential long-term health risks associated with regular alcohol consumption? Key concerns include:

• Liver damage: Chronic alcohol use can lead to fatty liver disease, alcoholic hepatitis, and cirrhosis.
• Cardiovascular issues: Increased risk of high blood pressure, heart disease, and stroke.
• Digestive problems: Chronic gastritis, ulcers, and increased risk of certain cancers.
• Neurological effects: Cognitive impairment, memory problems, and increased risk of dementia.
• Mental health impacts: Higher rates of depression, anxiety, and other mental health disorders.

These long-term risks underscore the importance of moderate alcohol consumption and seeking help if you find it difficult to control your drinking habits.

Defining Moderate Alcohol Consumption

What constitutes moderate drinking? According to health guidelines:

• For men: Up to 2 drinks per day
• For women: Up to 1 drink per day

It’s important to note that these are general guidelines and individual tolerance can vary based on factors like body weight, metabolism, and overall health.

When to Seek Medical Attention for Alcohol-Related Issues

Understanding when to seek professional medical help for alcohol-related issues is crucial for maintaining health and preventing serious complications. While occasional overindulgence might not require medical intervention, certain situations call for immediate attention.

When should you consider seeking medical help for alcohol-related issues? Key situations include:

1. Severe hangover symptoms lasting more than 24 hours
2. Signs of alcohol poisoning (confusion, vomiting, seizures, slow breathing)
3. Symptoms of withdrawal when attempting to stop or reduce alcohol consumption
4. Persistent digestive issues or unexplained pain after drinking
5. Difficulty controlling alcohol intake or feeling dependent on alcohol

It’s always better to err on the side of caution when it comes to your health. If you’re unsure whether your symptoms warrant medical attention, consulting with a healthcare professional can provide peace of mind and ensure you receive appropriate care if needed.

Support for Alcohol Use Disorders

For those struggling with alcohol dependence or addiction, various support systems are available:

• Alcoholics Anonymous (AA) and similar support groups
• Cognitive Behavioral Therapy (CBT)
• Medication-assisted treatment
• Inpatient and outpatient rehabilitation programs

Remember, seeking help for alcohol-related issues is a sign of strength, not weakness. Professional support can be instrumental in managing alcohol use and improving overall health and well-being.

The Role of Preventive Measures in Alcohol Consumption

While understanding how to manage the aftermath of excessive drinking is important, implementing preventive measures can significantly reduce the need for remedies like Pepto-Bismol in the first place. Adopting responsible drinking habits not only minimizes the risk of immediate discomfort but also contributes to long-term health and well-being.

How can you practice responsible alcohol consumption? Consider the following strategies:

1. Set limits: Decide on a maximum number of drinks before you start and stick to it.
2. Pace yourself: Alternate alcoholic beverages with water or non-alcoholic drinks.
3. Eat before and while drinking: Food can slow alcohol absorption and reduce its effects.
4. Know your limits: Understand your personal tolerance and avoid peer pressure to exceed it.
5. Plan ahead: Arrange for safe transportation if you plan to drink.
6. Stay hydrated: Drink water throughout the evening to combat dehydration.

By incorporating these practices into your routine, you can significantly reduce the likelihood of experiencing severe hangover symptoms or needing to rely on medications like Pepto-Bismol after drinking.

The Importance of Alcohol Education

Promoting awareness about responsible alcohol consumption is crucial. This includes:

• Understanding alcohol content in different beverages
• Recognizing the signs of alcohol abuse and dependence
• Learning about the short-term and long-term health effects of alcohol
• Being aware of how alcohol can interact with medications and health conditions

Increased education and awareness can lead to more informed decisions about alcohol consumption, potentially reducing the incidence of alcohol-related health issues and the need for interventions like Pepto-Bismol use after drinking.

What Can Happen If You Combine Pepto-Bismol and Alcohol?

The pink liquid or pink pill of bismuth subsalicylate (commonly known by the brand name Pepto-Bismol) can relieve symptoms like upset stomach and diarrhea. So when you’ve overdone it on the alcohol, it may sound like a great plan for easing your stomach woes.

However, there are some reasons why Pepto-Bismol and alcohol may not mix as well as a Jack and Coke did the night before. Keep reading for some considerations before reaching for the Pepto when your stomach hurts.

Pepto’s active ingredient, bismuth subsalicylate, has anti-inflammatory properties that reduce the irritation that can cause diarrhea and upset stomach.

The medicine also coats the stomach lining, which acts as a barrier between the stomach lining and the substances that could irritate the stomach, such as stomach acid.

Pepto also has antimicrobial effects. For this reason, doctors prescribe it to treat H. pyloriinfections that can cause acid reflux and upset stomach.

Alcohol can irritate the stomach lining and cause a symptom known as gastritis. The condition can cause symptoms such as:

• bloating
• diarrhea
• food regurgitation
• nausea
• upper abdominal pain
• vomiting

Periodic gastritis from a night of overindulging usually isn’t that bad. However, those who have alcohol use disorder or often binge drink can experience damage due to chronic inflammation in the stomach lining. This can result in ulcers and gastrointestinal (GI) bleeding.

The main reason why Pepto and alcohol don’t mix well is that the liver is (at least in part) responsible for metabolizing both alcohol and Pepto-Bismol. While the gastrointestinal tract is mostly responsible for absorbing the active ingredients in Pepto-Bismol, it’s believed the liver breaks some down as well.

The potential problem with this is if the liver is too busy breaking down one drug, it may not break the other down as effectively. This can potentially damage the liver and also extend the amount of time both Pepto-Bismol and alcohol are present in the body.

Doctors also worry about the use of Pepto-Bismol and alcohol if a person has ulcers. These are areas of the stomach that aren’t protected by the stomach’s lining, and can result in pain and bleeding. The combination of alcohol and Pepto-Bismol can increase the risks for GI bleeding.

One sign to look for

If you do use Pepto to try and relieve your upset stomach while drinking or after drinking, watch your stool for symptoms of GI bleeding. This can include bright or dark red blood in your stool.

Pepto can turn your stool black, so this change in color doesn’t necessarily mean you have a problem.

Biggest concerns of combining both

• both staying in your body longer and/or taking longer to process
• overworking the liver and possible liver damage
• increased chance of GI bleeding

Was this helpful?

A lot of the potential interactions between Pepto-Bismol and alcohol are theoretical. There aren’t a lot of medical reports from people who’ve been harmed by the alcohol-and-Pepto combo. But there also aren’t any studies in the past few decades that show taking Pepto after drinking is beneficial or safe.

There are a few studies from the 1990s that didn’t report side effects from using Pepto and drinking. One from 1990 published in the Journal of International Medical Research studied 132 volunteers who drank to excess and took either Pepto or a placebo.

At the end of the study, they didn’t find any side effects from taking the medicine and drinking. The participants who took Pepto did report better symptom relief. Again, this is an older study and one of the few that looked at Pepto and alcohol.

A hangover is the combination of dehydration, irritation to your stomach and your body’s efforts to clear the alcohol from your system. Unfortunately, there’s not a lot you can do other than let time pass and your body clear the alcohol from your system.

Doctors haven’t proven any definitive methods for curing or speeding up a hangover’s symptoms — this even includes studies on giving intravenous (IV) fluids and taking a pain reliever before bed.

Hydrate

You can drink water or other electrolyte-containing beverages in an attempt to re-hydrate. But drinking plenty of fluids is a healthy idea whether you have a hangover or not.

Eat carefully

Until you feel better, you can also eat bland foods that aren’t likely to upset your stomach further. These include:

• applesauce
• bananas
• broth
• plain crackers
• toast

Get checked after a day

If you don’t feel better after about 24 hours, you may want to see your doctor in case your symptoms may be related to another medical condition.

Pepto-Bismol and alcohol have some potential interactions that make most doctors warn against using them at the same time. While you may be able to use both at the same time, Pepto probably won’t help you feel better after drinking or prevent later hangover symptoms. As a result, it’s probably better skipped.

What Can Happen If You Combine Pepto-Bismol and Alcohol?

The pink liquid or pink pill of bismuth subsalicylate (commonly known by the brand name Pepto-Bismol) can relieve symptoms like upset stomach and diarrhea. So when you’ve overdone it on the alcohol, it may sound like a great plan for easing your stomach woes.

However, there are some reasons why Pepto-Bismol and alcohol may not mix as well as a Jack and Coke did the night before. Keep reading for some considerations before reaching for the Pepto when your stomach hurts.

Pepto’s active ingredient, bismuth subsalicylate, has anti-inflammatory properties that reduce the irritation that can cause diarrhea and upset stomach.

The medicine also coats the stomach lining, which acts as a barrier between the stomach lining and the substances that could irritate the stomach, such as stomach acid.

Pepto also has antimicrobial effects. For this reason, doctors prescribe it to treat H. pyloriinfections that can cause acid reflux and upset stomach.

Alcohol can irritate the stomach lining and cause a symptom known as gastritis. The condition can cause symptoms such as:

• bloating
• diarrhea
• food regurgitation
• nausea
• upper abdominal pain
• vomiting

Periodic gastritis from a night of overindulging usually isn’t that bad. However, those who have alcohol use disorder or often binge drink can experience damage due to chronic inflammation in the stomach lining. This can result in ulcers and gastrointestinal (GI) bleeding.

The main reason why Pepto and alcohol don’t mix well is that the liver is (at least in part) responsible for metabolizing both alcohol and Pepto-Bismol. While the gastrointestinal tract is mostly responsible for absorbing the active ingredients in Pepto-Bismol, it’s believed the liver breaks some down as well.

The potential problem with this is if the liver is too busy breaking down one drug, it may not break the other down as effectively. This can potentially damage the liver and also extend the amount of time both Pepto-Bismol and alcohol are present in the body.

Doctors also worry about the use of Pepto-Bismol and alcohol if a person has ulcers. These are areas of the stomach that aren’t protected by the stomach’s lining, and can result in pain and bleeding. The combination of alcohol and Pepto-Bismol can increase the risks for GI bleeding.

One sign to look for

If you do use Pepto to try and relieve your upset stomach while drinking or after drinking, watch your stool for symptoms of GI bleeding. This can include bright or dark red blood in your stool.

Pepto can turn your stool black, so this change in color doesn’t necessarily mean you have a problem.

Biggest concerns of combining both

• both staying in your body longer and/or taking longer to process
• overworking the liver and possible liver damage
• increased chance of GI bleeding

Was this helpful?

A lot of the potential interactions between Pepto-Bismol and alcohol are theoretical. There aren’t a lot of medical reports from people who’ve been harmed by the alcohol-and-Pepto combo. But there also aren’t any studies in the past few decades that show taking Pepto after drinking is beneficial or safe.

There are a few studies from the 1990s that didn’t report side effects from using Pepto and drinking. One from 1990 published in the Journal of International Medical Research studied 132 volunteers who drank to excess and took either Pepto or a placebo.

At the end of the study, they didn’t find any side effects from taking the medicine and drinking. The participants who took Pepto did report better symptom relief. Again, this is an older study and one of the few that looked at Pepto and alcohol.

A hangover is the combination of dehydration, irritation to your stomach and your body’s efforts to clear the alcohol from your system. Unfortunately, there’s not a lot you can do other than let time pass and your body clear the alcohol from your system.

Doctors haven’t proven any definitive methods for curing or speeding up a hangover’s symptoms — this even includes studies on giving intravenous (IV) fluids and taking a pain reliever before bed.

Hydrate

You can drink water or other electrolyte-containing beverages in an attempt to re-hydrate. But drinking plenty of fluids is a healthy idea whether you have a hangover or not.

Eat carefully

Until you feel better, you can also eat bland foods that aren’t likely to upset your stomach further. These include:

• applesauce
• bananas
• broth
• plain crackers
• toast

Get checked after a day

If you don’t feel better after about 24 hours, you may want to see your doctor in case your symptoms may be related to another medical condition.

Pepto-Bismol and alcohol have some potential interactions that make most doctors warn against using them at the same time. While you may be able to use both at the same time, Pepto probably won’t help you feel better after drinking or prevent later hangover symptoms. As a result, it’s probably better skipped.

what you need to know – Drink-Drink

Introduction

Chances are you’ve heard of “pink”. Pepto-Bismol is a well-known over-the-counter medication that is used to treat digestive problems.

If you feel a bit nauseous, read on to find out what to expect when taking Pepto-Bismol and how to use it safely.

What is pepto-bismol?

Pepto-Bismol is used to treat diarrhea and relieve symptoms of indigestion. These symptoms may include:

• heartburn
• nausea
• upset stomach
• gas
• belching
• feeling full

Pepto-Bis active ingredient mole is called bismuth subsalicylate. It belongs to a class of drugs called salicylates.

Pepto-Bismol is available in regular strength capsules, chewable tablets and liquid. It is available in maximum concentration as liquid and capsules. All forms are taken internally.

How does it work?

Pepto-Bismol is said to treat diarrhea by:

• increasing the amount of fluid your intestines absorb
• reducing inflammation and intestinal hyperactivity
• preventing your body from releasing a chemical called prostaglandin that causes inflammation

90 013 blocking toxins, produced by bacteria such as

• kills other bacteria that cause diarrhea

The active ingredient, bismuth subsalicylate, also has antacid properties that help reduce heartburn, indigestion and nausea.

dosage

Adults and children 12 years of age and older may take the following forms of Pepto-Bismol for up to 2 days. The dosages given below apply to all digestive problems that Pepto-Bismol can help solve.

When treating diarrhea, be sure to drink plenty of water to replace lost fluids. Keep drinking liquids even if you are using Pepto Bismol.

If your condition lasts more than 2 days or you have ringing in your ears, stop taking Pepto-Bismol and contact your doctor.

Liquid Suspension

Initial Strength:

• Take 30 milliliters (ml) every 30 minutes or 60 ml every hour as needed.
• Do not exceed eight doses (240 ml) in 24 hours.
• Do not use for more than 2 days. See your doctor if diarrhea lasts longer than this.
• Pepto-Bismol Original Liquid also comes in a cherry flavor, both of which have the same dosing instructions.

Pepto-Bismol Ultra (maximum strength):

• Take 15 ml every 30 minutes or 30 ml every hour as needed.
• Do not exceed eight doses (120 ml) in 24 hours.
• Do not use for more than 2 days. Contact your doctor if symptoms do not improve.
• Pepto-Bismol Ultra also comes in a cherry flavor with identical dosing instructions.

Another liquid version is known as Pepto Cherry Diarrhea. This product is for the treatment of diarrhea only. This is the same product as Pepto-Bismol Original or Ultra cherry flavored. It is also for people 12 years and older.

The following is the recommended dosage for Pepto Cherry Diarrhe:

• Take 10 ml every 30 minutes or 20 ml every hour as needed.
• Do not exceed eight doses (80 ml) in 24 hours.
• Do not use for more than 2 days. See your doctor if diarrhea still persists.

Chewable Tablets

For Pepto Gummies:

• Take two tablets every 30 minutes or four tablets every 60 minutes as needed.
• Chew or dissolve tablets in your mouth.
• Do not exceed eight doses (16 tablets) in 24 hours.
• Stop taking this medicine and call your doctor if diarrhea does not go away after 2 days.

Caplets

Original Caplets:

• Take two capsules (262 milligrams each) every 30 minutes or four capsules every 60 minutes as needed.
• Swallow the capsules whole with water. Don’t chew them.
• Do not exceed eight capsules per day.
• Do not use for more than 2 days.
• Seek medical attention if diarrhea persists.

Ultra Caps:

• Take one capsule (525 mg) every 30 minutes or two capsules every 60 minutes as needed.
• Swallow the capsules with water. Don’t chew them.
• Do not exceed eight capsules in 24 hours. Do not use for more than 2 days.
• Seek medical attention if diarrhea persists for more than 2 days.

Pepto Diarrhea Caplets:

• Take one capsule every 30 minutes or two capsules every 60 minutes as needed.
• Swallow the capsules with water. Don’t chew them.
• Do not exceed eight capsules per day.
• Do not use for more than 2 days. Call your doctor if diarrhea lasts longer than this time.

Pepto Original LiquiCaps or LiquiCaps for diarrhea:

• Take two LiquiCaps (262 mg each) every 30 minutes or four LiquiCaps every 60 minutes as needed.
• Do not exceed 16 LiquiCaps in 24 hours.
• Do not use for more than 2 days. See your doctor if diarrhea lasts longer than this.

Children

The above products and dosages are for people 12 years of age and older. Pepto-Bismol offers a separate product intended for children up to 12 years of age in the form of chewable tablets.

This product is indicated for the treatment of heartburn and indigestion in young children. Please note that dosages are based on weight and age.

Pepto Kids Chewables:

• One tablet for children 24 to 47 pounds and 2 to 5 years. Do not take more than three tablets in 24 hours.
• Two tablets for children 48 to 95 pounds and 6 to 11 years. Do not take more than six tablets in a 24 hour period.
• Do not use in children under 2 years of age or weighing less than 24 pounds unless directed by a physician.
• Call your child’s pediatrician if symptoms do not improve within 2 weeks.

Side effects

Most of the side effects of Pepto-Bismol are minor and disappear soon after the medication is stopped.

More common side effects

More common side effects of pepto-bismol include:

• black stools
• black, hairy tongue

These side effects are harmless. Both effects are temporary and disappear within a few days of stopping Pepto-Bismol.

Q:

Why can Pepto-Bismol give me black stools and a black hairy tongue?

Question asked by a reader

A:

Pepto-Bismol contains a substance called bismuth. When this substance mixes with sulfur (a mineral in your body), it forms another substance called bismuth sulfide. This stuff is black.

When formed in your digestive tract, it mixes with food as you digest it. This makes your chair black. When bismuth sulfide forms in your saliva, it turns your tongue black. It also causes dead skin cells to build up on the surface of your tongue, which can make your tongue look furry.

Drink-Drink Medical Team The answers represent the opinions of our medical experts. All content is for informational purposes only and should not be considered medical advice.

Serious side effect

Tinnitus is an uncommon but serious side effect of Pepto-Bismol. If you have this side effect, stop taking Pepto-Bismol and call your doctor right away.

interaction with other drugs

Pepto-Bismol may interact with any other medicines you may be taking. Talk to your pharmacist or doctor to see if Pepto-Bismol interacts with any medicines you are taking.

Examples of drugs that may interact with Pepto-Bismol include:

• angiotensin-converting enzyme (ACE) inhibitors such as benazepril, captopril, enalapril, fosinopril, lisinopril and trandolapril
• anticonvulsants, such as valproic acid and divalproex
• blood thinners (anticoagulants) such as warfarin
• diabetes drugs such as insulin, metformin, sulfonylurea, dipeptidyl peptidase-4 (DPP-4) inhibitors and sodium glucose cotransporter-2 (SGLT-2) inhibitors
• drugs for gout, such as probenecid
• methotrexate
• non-steroidal anti-inflammatory drugs (NSAIDs), such as aspirin, naproxen, ibuprofen, meloxicam, indomethacin and diclofenac
• other salicylates, such as aspirin
• phenytoin
• tetracycline antibiotics such as demeclocycline, doxycycline, minocycline, and tetracycline

Definition

An interaction is when a substance changes how a drug works. This may harm or interfere with the drug.

Warnings

Pepto-Bismol is generally safe for most people, but avoid it if you have certain medical conditions. Pepto-Bismol may aggravate them.

Do not take Pepto-Bismol if you are:

• allergic to salicylates (including aspirin or NSAIDs such as ibuprofen, naproxen and celecoxib)
• have an active bleeding ulcer who has or is recovering for chickenpox or flu-like symptoms

Bismuth subsalicylate may also cause problems in people with other medical conditions.

Tell your doctor if you have any of the following conditions before taking Pepto-Bismol. They can tell you if Pepto Bismol is safe to use. These conditions include:

• stomach ulcers
• bleeding problems such as hemophilia and von Willebrand disease
• kidney problems
• gout
• diabetes

Stop taking Pepto -Bismol and see a doctor immediately if you are vomiting and severe diarrhea, as well as behavioral changes such as:

• loss of energy
• aggressive behavior
• confusion

These symptoms may be early signs of Reye’s syndrome. This is a rare but serious condition that can affect your brain and liver.

Avoid using Pepto-Bismol for self-treatment of diarrhea if you have a fever or if your stool contains blood or mucus. If you have these symptoms, call your doctor right away. They may be signs of a serious health condition, such as an infection.

In case of overdose

Symptoms of an overdose of Pepto-Bismol may include:

If you think you have taken too much, call your doctor or local poison control center. If you have severe symptoms, call 911 or your local emergency services, or go to the nearest emergency room right away.

Talk to your doctor

For many people, Pepto-Bismol is a safe and easy way to relieve common stomach problems. But if you have any concerns about whether Pepto-Bismol is a safe option for you, be sure to ask your doctor or pharmacist.

Also call your doctor if Pepto-Bismol does not relieve your symptoms after 2 days.

Buy Pepto Bismol.

Dosage Warning

This product should not be used in children under 12 years of age.

Bismuth subsalicylate | is… What is Bismuth Subsalicylate?

Bismuth subsalicylate , empirical formula C ₇ H ₅ BiO ₄ , is a colloidal substance obtained by hydrolysis of bismuth salicylate (Bi{C ₆ H ₄ (OH)CO ₂ } ₃ ). The actual structure is unknown and its formula is approximate. Recent evidence suggests that it consists of a bismuth oxide core with salicylate ions attached to its surface. A structure model has recently been published and has the composition Bi ₃₈ O ₄₄ {C ₆ H ₃ (OH)CO ₂ } ₂₆ . It is a drug used to treat heartburn, indigestion, indigestion, and nausea. Better known as pink bismuth , it is the active ingredient in drugs such as Pepto-Bismol (Pepto-Bismol), and since 2003 Kaopektat. Used as a drug since 1901.

Pharmacology

As a derivative of salicylic acid, bismuth subsalicylate exhibits anti-inflammatory and bactericidal effects, and also acts as an antacid.

It has a pronounced activity against Helicobacter pylori. Forms an insoluble protective coating at the site of the ulcer, increases the resistance of the gastric mucosa to the effects of pepsin, hydrochloric acid and digestive enzymes. Bismuth subsalicylate increases the production of mucus in the stomach and improves its protective properties.

Structure

The prefix “sub” in the name refers to the high oxygen content in the molecule and the presence of Bi-O fragments in the molecule.

Characterization of bismuth subsalicylate is difficult due to its insolubility and partial hydrolysis. Two crystal structures have been studied: 2 O) ₂ ] with Bi core ₃₈ O ₄₄

The last cluster is considered to lead to the previous one.