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Reviews on enbrel. Enbrel for Psoriatic Arthritis: Comprehensive Review and Patient Experiences

What is the average rating of Enbrel for psoriatic arthritis. How many users reported positive experiences with Enbrel. What are the most common side effects of Enbrel. How long does it typically take for Enbrel to show results in psoriatic arthritis patients. What are the alternatives to Enbrel for treating psoriatic arthritis.

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Overview of Enbrel for Psoriatic Arthritis Treatment

Enbrel (etanercept) is a widely used medication for treating psoriatic arthritis, a chronic inflammatory condition that affects both the skin and joints. Based on reviews from Drugs.com, Enbrel has received an average rating of 7.6 out of 10 from 51 reviews specifically for psoriatic arthritis treatment. This rating suggests that a significant number of patients have found Enbrel to be effective in managing their condition.

Breaking down the ratings further:

  • 73% of reviewers reported a positive experience with Enbrel
  • 20% reported a negative experience
  • 37% gave Enbrel a perfect 10/10 rating
  • 20% rated it 9/10
  • 16% rated it 8/10

These statistics indicate that the majority of users have found Enbrel to be beneficial in treating their psoriatic arthritis symptoms.

Mechanism of Action and Effectiveness

Enbrel belongs to a class of drugs known as tumor necrosis factor (TNF) inhibitors. It works by blocking the action of TNF, a protein in the body that causes inflammation. By reducing inflammation, Enbrel helps alleviate the symptoms of psoriatic arthritis, including joint pain, stiffness, and skin lesions.

The high percentage of positive reviews suggests that Enbrel is effective for many patients in managing their psoriatic arthritis symptoms. However, individual responses can vary, and it’s important to note that what works for one person may not work as well for another.

Common Side Effects and Safety Considerations

While Enbrel has proven effective for many patients, it’s crucial to be aware of potential side effects. Common side effects reported by users include:

  • Injection site reactions (redness, itching, pain)
  • Increased risk of infections
  • Headaches
  • Nausea
  • Fatigue

Is Enbrel safe to use with other medications? Caution is advised when combining Enbrel with certain drugs. For instance, can Enbrel be taken with antibiotics? While it’s generally possible, it’s essential to consult with a healthcare provider, as some antibiotics may increase the risk of infections when combined with Enbrel.

Can you take Enbrel with a cold? It’s generally recommended to avoid taking Enbrel during active infections, including colds. Patients should consult their doctor if they develop any signs of infection while on Enbrel.

Enbrel vs. Alternative Treatments for Psoriatic Arthritis

While Enbrel has shown effectiveness in treating psoriatic arthritis, it’s not the only option available. Other treatments include:

  1. Other TNF inhibitors (e.g., Humira, Remicade)
  2. Interleukin inhibitors (e.g., Cosentyx, Taltz)
  3. JAK inhibitors (e.g., Xeljanz)
  4. Traditional disease-modifying antirheumatic drugs (DMARDs) like methotrexate
  5. Nonsteroidal anti-inflammatory drugs (NSAIDs)

How does Enbrel compare to these alternatives? The choice of treatment depends on various factors, including the severity of symptoms, individual patient characteristics, and potential side effects. Some patients may find that Enbrel works better for them than other options, while others might respond better to alternative treatments.

Dosage and Administration of Enbrel

Enbrel is typically administered via subcutaneous injection. The usual dosage for adult patients with psoriatic arthritis is 50 mg once weekly. However, some patients may be prescribed a different dosing regimen based on their individual needs and response to treatment.

How long does it take for Enbrel to work? Many patients report experiencing some improvement in symptoms within 1-2 weeks of starting treatment. However, it can take up to 3 months to see the full effects of Enbrel. Patients are advised to continue treatment as prescribed and communicate regularly with their healthcare provider about their progress.

Long-Term Use and Sustainability of Enbrel Treatment

For many patients with psoriatic arthritis, Enbrel is a long-term treatment option. The high percentage of positive reviews suggests that many users find sustained benefit from Enbrel over time. However, long-term use of any medication comes with considerations:

  • Regular monitoring by a healthcare provider is essential
  • Patients should be vigilant about potential side effects
  • The effectiveness of the medication may change over time for some patients

Is Enbrel a sustainable treatment option for psoriatic arthritis? For many patients, Enbrel provides long-term relief and improved quality of life. However, treatment plans should be regularly reviewed and adjusted as needed based on the individual’s response and any changes in their condition.

Patient Experiences and Quality of Life Improvements

The high percentage of positive reviews for Enbrel in treating psoriatic arthritis suggests that many patients experience significant improvements in their quality of life. Common benefits reported by users include:

  • Reduced joint pain and stiffness
  • Improved mobility and physical function
  • Clearer skin for those with psoriatic plaques
  • Increased ability to perform daily activities
  • Better overall well-being and mental health

How do these improvements impact patients’ daily lives? Many users report being able to return to activities they previously enjoyed but had to give up due to their condition. This can include everything from simple tasks like getting dressed without pain to more demanding activities like sports or travel.

Cost Considerations and Insurance Coverage

Enbrel, like many biologic medications, can be expensive. The cost of treatment is an important consideration for many patients. Some key points to consider:

  • Many insurance plans cover Enbrel, but coverage can vary
  • Co-pay assistance programs are available from the manufacturer
  • Biosimilar versions of Enbrel may offer more cost-effective options

What are biosimilar drugs? Biosimilars are highly similar versions of biologic medications like Enbrel. They undergo rigorous testing to ensure they have no clinically meaningful differences from the original drug in terms of safety and effectiveness. Biosimilars can often provide a more affordable option for patients.

What biosimilars have been approved in the United States for etanercept? As of 2024, the FDA has approved several biosimilars for Enbrel, including Erelzi and Eticovo. These options may provide more affordable alternatives for some patients, depending on their insurance coverage and individual circumstances.

Navigating Insurance and Financial Assistance

Given the potential high cost of Enbrel, it’s crucial for patients to explore all available options for financial assistance. This may include:

  • Discussing coverage options with their insurance provider
  • Exploring patient assistance programs offered by the manufacturer
  • Considering biosimilar alternatives if they are more affordable
  • Consulting with their healthcare provider about potential lower-cost treatment options

How can patients determine the most cost-effective treatment option for their psoriatic arthritis? It’s important to work closely with both healthcare providers and insurance companies to understand all available options and their associated costs. This may involve comparing the costs of different medications, exploring assistance programs, and considering the long-term value of various treatment options in managing the condition effectively.

Emerging Treatments and Future Directions

While Enbrel has been a mainstay in psoriatic arthritis treatment for many years, research into new therapies continues. What are the new drugs for the treatment of psoriatic arthritis? Some emerging treatments and areas of research include:

  • New biologic therapies targeting different inflammatory pathways
  • Oral small molecule inhibitors
  • Combination therapies
  • Personalized medicine approaches based on genetic markers

How might these new treatments compare to Enbrel? While it’s too early to say definitively, these new therapies aim to provide additional options for patients who may not respond well to current treatments or who experience side effects. They may also offer more convenient administration methods or more targeted approaches to treating psoriatic arthritis.

The Role of Lifestyle Modifications

In addition to medication, lifestyle modifications can play a crucial role in managing psoriatic arthritis. Some key areas that patients may focus on include:

  • Maintaining a healthy weight to reduce stress on joints
  • Regular exercise to improve joint flexibility and strength
  • Stress management techniques to help reduce flare-ups
  • Dietary changes to potentially reduce inflammation

How do these lifestyle changes complement Enbrel treatment? Many patients find that combining medication like Enbrel with lifestyle modifications leads to better overall management of their condition. These changes can help reduce the burden on joints, improve overall health, and potentially enhance the effectiveness of medical treatments.

Patient Support and Education

Managing a chronic condition like psoriatic arthritis can be challenging, and patient support and education play crucial roles in successful treatment. Many resources are available to help patients better understand their condition and treatment options:

  • Support groups (both in-person and online)
  • Educational materials from reputable health organizations
  • Patient advocacy organizations
  • Nurse educators and patient navigators provided by some healthcare systems or pharmaceutical companies

Why is patient education important in psoriatic arthritis treatment? Informed patients are better equipped to manage their condition, adhere to treatment plans, and communicate effectively with their healthcare providers. This can lead to better outcomes and improved quality of life.

Communicating with Healthcare Providers

Effective communication with healthcare providers is essential for optimal management of psoriatic arthritis. Patients should be prepared to discuss:

  • Changes in symptoms or new symptoms
  • Side effects of medications
  • Concerns about treatment costs or insurance coverage
  • Questions about alternative or complementary treatments
  • Impact of the condition on daily life and overall well-being

How can patients make the most of their appointments with healthcare providers? Keeping a symptom diary, preparing questions in advance, and being honest about any challenges or concerns can help ensure that patients receive the most appropriate care and support for their individual needs.

The Importance of Ongoing Research

Continued research into psoriatic arthritis and its treatments is crucial for improving patient outcomes. Current areas of focus include:

  • Identifying biomarkers to predict treatment response
  • Developing more targeted therapies
  • Investigating the underlying mechanisms of the disease
  • Exploring potential preventive strategies

How might ongoing research benefit patients with psoriatic arthritis? As our understanding of the condition grows, we may see more personalized treatment approaches, more effective therapies, and potentially even ways to prevent the onset or progression of psoriatic arthritis.

Participating in Clinical Trials

Some patients may have the opportunity to participate in clinical trials for new psoriatic arthritis treatments. While participation in trials carries both potential benefits and risks, it can be an important way for patients to access cutting-edge treatments and contribute to the advancement of medical knowledge.

What should patients consider before participating in a clinical trial? It’s important to thoroughly discuss the potential risks and benefits with healthcare providers, understand the commitments involved, and ensure that participation aligns with personal health goals and values.

Balancing Treatment Benefits and Risks

When considering Enbrel or any treatment for psoriatic arthritis, it’s crucial to balance the potential benefits against the risks. While the high percentage of positive reviews suggests that many patients find significant benefit from Enbrel, it’s important to remember that every individual’s experience is unique.

Factors to consider when evaluating treatment options include:

  • Severity of symptoms and impact on quality of life
  • Potential side effects and risks associated with the treatment
  • Long-term safety and effectiveness data
  • Personal health history and other medical conditions
  • Cost and accessibility of the treatment

How can patients make informed decisions about their psoriatic arthritis treatment? Open and ongoing communication with healthcare providers is key. Patients should feel empowered to ask questions, express concerns, and actively participate in decisions about their treatment plan.

The Role of Shared Decision-Making

Shared decision-making between patients and healthcare providers is increasingly recognized as an important aspect of effective healthcare. This approach involves:

  • Patients being fully informed about their condition and treatment options
  • Healthcare providers understanding patients’ preferences, values, and goals
  • Collaborative discussions to arrive at treatment decisions

Why is shared decision-making important in psoriatic arthritis treatment? This approach can lead to treatment plans that are better aligned with patients’ needs and preferences, potentially improving adherence and outcomes. It also empowers patients to take an active role in managing their health.

Enbrel Reviews & Ratings – Drugs.com

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Enbrel
has an average rating of 7.8 out of 10 from a total of 273 reviews
on Drugs.com.
72% of reviewers reported a positive experience, while 14% reported a negative experience.

Condition Avg. Rating ReviewsCompare
Rheumatoid Arthritis  134 reviews366 medications
Psoriatic Arthritis  55 reviews80 medications
Ankylosing Spondylitis  51 reviews151 medications
Plaque Psoriasis  16 reviews48 medications
Juvenile Rheumatoid Arthritis  11 reviews167 medications
Juvenile Idiopathic Arthritis  6 reviews23 medications
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Reviews for Enbrel

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Frequently asked questions

  • What are the new drugs for the treatment of rheumatoid arthritis (RA)?
  • What are biosimilar drugs?
  • Can Enbrel be taken with antibiotics?
  • Can you take Enbrel with a cold?

Are you taking this medicine?

  • Add your review
  • Learn more about Enbrel

More FAQ

  • What are the new drugs for the treatment of plaque psoriasis?
  • Does perispinal etanercept work for stroke recovery?
  • What biosimilars have been approved in the United States?
  • How long does it take for Enbrel to work?

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

More about Enbrel (etanercept)

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Related treatment guides

  • Rheumatoid Arthritis
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  • Psoriatic Arthritis
  • Juvenile Idiopathic Arthritis
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Enbrel User Reviews for Psoriatic Arthritis

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Enbrel
has an average rating of 7. 6 out of 10 from a total of 51 reviews
for the
treatment of Psoriatic Arthritis.
73% of reviewers reported a positive experience, while 20% reported a negative experience.

Filter by condition
All conditionsAnkylosing Spondylitis (51)Juvenile Idiopathic Arthritis (6)Juvenile Rheumatoid Arthritis (11)Plaque Psoriasis (16)Psoriatic Arthritis (55)Rheumatoid Arthritis (134)

Enbrel rating summary

7.6/10 average rating

51 ratings from 55 user reviews.

Compare all 69 medications used in the treatment of Psoriatic Arthritis.

1037%
920%
816%
74%
60%
54%
40%
36%
210%
14%

Reviews for Enbrel

Search keyword

Frequently asked questions

  • What are the new drugs for the treatment of rheumatoid arthritis (RA)?
  • What are biosimilar drugs?
  • Can Enbrel be taken with antibiotics?
  • Can you take Enbrel with a cold?

Are you taking this medicine?

  • Add your review
  • Learn more about Enbrel

More FAQ

  • What are the new drugs for the treatment of plaque psoriasis?
  • Does perispinal etanercept work for stroke recovery?
  • What biosimilars have been approved in the United States?
  • How long does it take for Enbrel to work?

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Psoriatic Arthritis

Symptoms and treatments
  • Psoriatic arthritis

More about Enbrel (etanercept)

  • Check interactions
  • Compare alternatives
  • Pricing & coupons
  • Reviews (304)
  • Drug images
  • Side effects
  • Dosage information
  • Patient tips
  • During pregnancy
  • Support group
  • FDA approval history
  • Drug class: antirheumatics
  • Breastfeeding
  • En español

Patient resources

  • Drug Information
  • Enbrel (Etanercept Prefilled Syringes)
  • Enbrel (Etanercept Vials)
  • Enbrel SureClick
Other brands

Erelzi, Eticovo

Professional resources

  • Prescribing Information

Related treatment guides

  • Rheumatoid Arthritis
  • Ankylosing Spondylitis
  • Psoriatic Arthritis
  • Juvenile Idiopathic Arthritis
  • Juvenile Rheumatoid Arthritis
  • Plaque Psoriasis

ENBREL reviews – divorce or truth?

The information provided on this site is for informational purposes only and is not intended for self-treatment! Any appointments are made by a doctor, there are contraindications and adverse reactions!

What is rheumatoid arthritis?

Juvenile idiopathic arthritis is a chronic pathology, severe and progressive disease of the joints and cartilage inflammation in children and adolescents. There are a lot of reasons for development, but they are all due to disorders of the immune system. The most likely catalyst for the development of arthritis is an infection with pathogenic strains of bacteria.

When an infection is affected, a reaction to the inflammatory process occurs and the destruction of the connective tissue, which is associated with degenerative and dystrophic disorders, is added. And if treatment is not started in a timely manner, then after degenerative destruction of cartilage tissues, there will be a complete deformation of the joints. And this already entails a limitation of the mobility of the joints and bone joints of the lower extremities of the musculoskeletal system.

What exactly causes juvenile arthritis? Most often, doctors call a genetic predisposition, infectious lesions, intoxication, joint reactions to certain drugs, chronic diseases affecting the joint cavity, and so on. With arthritis, if no drugs are used, the following symptoms may appear: painful syndrome in the joint cavity of varying intensity, edematous syndrome, redness at the site of the lesion, body temperature disturbance due to an inflammatory focus in the connective tissue, limited movement, feeling of stiffness, impossibility perform some limb manipulations and the like.

To make an accurate diagnosis and prescribe therapy, the patient must first of all consult a specialist and undergo a full course of examination. This may include: ultrasound of the joint cavity, X-ray, MRI or CT, blood tests and other types of diagnostics. All these examinations will establish a causal relationship between the occurrence of an inflammatory focus in the body, and subsequently the doctor will recommend drug therapy. It is better not to self-medicate, since there is a high probability of developing severe complications up to the complete disability of the patient.

Systemic drug therapy

As a drug therapy, the doctor may prescribe a complex treatment using various groups of drugs. For the treatment of rheumatoid arthritis, the following categories of medicines are most often used (at the discretion of the attending physician): non-steroidal anti-inflammatory drugs (NSAIDs) – are necessary to reduce pain, inflammation, and eliminate symptoms. Basic antirheumatic drugs: they are designed to eliminate inflammatory foci, soften osteoarticular decomposition (destruction of bones and joints). Glucocorticosteroid preparations can also be recommended, which are designed to normalize metabolic processes, restore normal blood circulation in the joint cavity. Biological active agents to eliminate enzyme deficiency, to prevent decomposition and destruction of nearby tissues and articular joints. Muscle relaxants – drugs in the presence of neurological pain and disorders, substances are designed to relax skeletal muscle tissue, increase the range of motion.

Enbrel and the pharmacological properties of the drug

Enbrel is an immunosuppressive agent. What it is? Immunosuppressants are substances that suppress the human immune system, in other words, weaken it. What is it for? Most often, immunosuppressants are used as a drug in transplantology to prevent rejection of tissues and organs, in the treatment of autoimmune diseases, allergic diseases. Enbrel also falls into this category, since rheumatoid arthritis is most often caused by the causes of an autoimmune disorder. the active substance here is: Etanercept, available in the form of a 50 mg solution and a 25 mg lyophilisate vial. this drug is an alpha cytokine inhibitor that supports the inflammatory process. By the way, with an increase in the level of alpha cytokines, which always happens with rheumatoid arthritis, it can be found in the synovial fluid in psoriatic arthritis, in the synovial fluid in ankylosing spondylitis. Therefore, the substance etanercept blocks the production of this cytokine and reduces its activity. It improves the patient’s activity, reduces the risk of complications and damage to other joint cavities.

Indications for prescribing

For which disorders is the drug prescribed? Indications are: active and progressive form of psoriatic arthritis, rheumatoid arthritis, rheumatoid arthritis monotherapy, juvenile idiopathic polyarthritis in children and adolescents, ankylosing spondylitis, psoriasis in children and adults, and so on. For full information, read the instructions or consult your doctor.

Contraindications and adverse reactions

However, Enbrel cannot be used as a stand-alone medicine, as it has contraindications and there are risks of complications. Enbrel is not recommended for use in case of hypersensitivity to the active substance, chronic infectious lesions, tuberculosis, sepsis, pregnancy, lactation, children under three years of age. It is necessary to be careful if the patient has heart failure, hepatitis, diabetes mellitus and other chronic pathologies. Most often, among the undesirable reactions from the body are: itching, fever, bleeding, subcutaneous hematoma, soreness, edematous syndrome, convulsions, bronchial asthma, rash, and the like. Be sure to tell your doctor about all the symptoms you have, if the drug brings discomfort, it is likely that either the dosage is incorrect or the drug itself is not suitable at all. Then you should think about replacing it with a similar tool.

Enbrel: how to use the medicine correctly?

The drug must be administered subcutaneously! The treatment regimen, dosage, frequency of administration, duration of the course of treatment is recommended exclusively purely individually based on the clinical data of the patient. In each case, a personalized therapy regimen is recommended, especially for children and adolescents. The medicine must be injected subcutaneously into certain areas of the body: the anterior part of the abdominal wall, the middle part of the thigh, the outer part of the shoulder. Each time you need to inject into different places, if you inject into the same place, you must take into account the distance between them of 3 centimeters. Do not inject the medicine into scars, scars, stretch marks, red inflamed skin, painful or damaged tissue. Read the instructions for how to properly prepare the solution for use. Do not reuse the same syringe and needle, and do not use other syringes. Enbrel significantly reduces the inflammatory process in autoimmune diseases.

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The effectiveness of a new genetically engineered drug in the treatment of back pain the results of which were published in the journal

Annals of Internal Medicine injections of etanercept (a new type of genetically engineered anti-inflammatory drug) are not as effective in reducing severe pain in the back and for sciatica, as are the standard spinal steroid injections currently practiced.

This study was supervised by Dr. Steven P Cohen, Associate Professor of Anesthesiology and Critical Care at Johns Hopkins University in Baltimore, Maryland.

He opined that medical professionals have long been looking for ways to reduce pain that would be safe and reliable alternatives to steroids as a treatment for sciatica. Current treatment, in which steroids are injected into the spine, often has mixed results, and only relieves pain temporarily. The introduction of steroids also has a high potential for the development of “catastrophic complications”.

Etanercept is a genetically engineered tumor necrosis factor (FINO) inhibitor currently used to treat rheumatoid arthritis and other autoimmune disorders where the patient’s own immune system attacks the patient’s healthy tissue, causing damage, pain, and swelling.

Cohen stated that the research interest in etanercept, marketed under the trade name Enbrel, arose from attempts to relieve or reduce the pain caused by compression of a herniated disc on the roots in the lumbar or cervical spine.

The drug works by blocking tumor necrosis factor, which is produced in the body and is involved in the development of the inflammatory response. Unlike steroids, which tend to target inflammation broadly, TNF inhibitors target specific inflammatory molecules that cause pain in sciatica and other conditions. They do this by blocking nerve receptors that cannot bind to TNF molecules and should theoretically completely block pain manifestations.

However, Cohen stated, “While this new drug only offers some promise, at least at the doses that have been given (doses considered safe) the steroids still work better.”

For the blind, placebo In a controlled study, 84 adult patients with sciatica who had received epidural injections for less than 6 months were randomized to receive either 60mg of the steroid, 4mg of etanercept, or 2mL of saline.

The idea of ​​administering epidural injections to patients with sciatica was based on the need to provide pain relief with lower dosage steroids, and thus to achieve fewer side effects compared to oral or parenteral steroids. , since with an epidural injection there is a direct effect on the focus of inflammation in the region of the compressed root.

A long-term study was conducted at several military and civilian treatment centers. The pharmacists prepared the epidural injection syringes, while neither the doctors nor the nurses who evaluated the results knew which patients were receiving which drugs.

The results showed that one month after receiving the second of two injections, patients who received steroids reported less pain and improved ability to work than patients who received etanercept or saline placebo.

However, Cohen and his colleagues found that while the steroids worked, their effect was temporary.

Cohen notes that in another study published recently, where patients received twice the dose of etanercept, patients noted the effect lasted two weeks longer than with steroids.

These data may suggest that the effect of etanercept is negligible at low doses and that higher doses may be required, which in turn warrants further research into the potential of this new drug.