Reviews on enbrel: Enbrel Reviews & Ratings – Drugs.com
Enbrel Reviews & Ratings – Drugs.com
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Enbrel
has an average rating of 7.8 out of 10 from a total of 273 reviews
on Drugs.com.
72% of reviewers reported a positive experience, while 14% reported a negative experience.
| Condition | Avg. Rating | Reviews | Compare |
|---|---|---|---|
| Rheumatoid Arthritis | 134 reviews | 366 medications | |
| Psoriatic Arthritis | 55 reviews | 80 medications | |
| Ankylosing Spondylitis | 51 reviews | 151 medications | |
| Plaque Psoriasis | 16 reviews | 48 medications | |
| Juvenile Rheumatoid Arthritis | 11 reviews | 167 medications | |
| Juvenile Idiopathic Arthritis | 6 reviews | 23 medications | |
| Add your review | |||
Reviews for Enbrel
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Frequently asked questions
- What are the new drugs for the treatment of rheumatoid arthritis (RA)?
- What are biosimilar drugs?
- Can Enbrel be taken with antibiotics?
- Can you take Enbrel with a cold?
Are you taking this medicine?
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- Learn more about Enbrel
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- What are the new drugs for the treatment of plaque psoriasis?
- Does perispinal etanercept work for stroke recovery?
- What biosimilars have been approved in the United States?
- How long does it take for Enbrel to work?
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content.
Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.
More about Enbrel (etanercept)
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- Enbrel (Etanercept Prefilled Syringes)
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Other brands
Erelzi, Eticovo
Professional resources
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Related treatment guides
- Rheumatoid Arthritis
- Ankylosing Spondylitis
- Psoriatic Arthritis
- Juvenile Idiopathic Arthritis
- Juvenile Rheumatoid Arthritis
- Plaque Psoriasis
Enbrel User Reviews for Psoriatic Arthritis
Save
Enbrel
has an average rating of 7.
6 out of 10 from a total of 51 reviews
for the
treatment of Psoriatic Arthritis.
73% of reviewers reported a positive experience, while 20% reported a negative experience.
Filter by condition
All conditionsAnkylosing Spondylitis (51)Juvenile Idiopathic Arthritis (6)Juvenile Rheumatoid Arthritis (11)Plaque Psoriasis (16)Psoriatic Arthritis (55)Rheumatoid Arthritis (134)
Enbrel rating summary
7.6/10 average rating
51 ratings from 55 user reviews.
Compare all 69 medications used in the treatment of Psoriatic Arthritis.
| 10 | 37% | |
|---|---|---|
| 9 | 20% | |
| 8 | 16% | |
| 7 | 4% | |
| 6 | 0% | |
| 5 | 4% | |
| 4 | 0% | |
| 3 | 6% | |
| 2 | 10% | |
| 1 | 4% |
Reviews for Enbrel
Search keyword
Frequently asked questions
- What are the new drugs for the treatment of rheumatoid arthritis (RA)?
- What are biosimilar drugs?
- Can Enbrel be taken with antibiotics?
- Can you take Enbrel with a cold?
Are you taking this medicine?
- Add your review
- Learn more about Enbrel
More FAQ
- What are the new drugs for the treatment of plaque psoriasis?
- Does perispinal etanercept work for stroke recovery?
- What biosimilars have been approved in the United States?
- How long does it take for Enbrel to work?
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content.
Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.
Learn more about Psoriatic Arthritis
Symptoms and treatments
- Psoriatic arthritis
More about Enbrel (etanercept)
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (304)
- Drug images
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- FDA approval history
- Drug class: antirheumatics
- Breastfeeding
- En español
Patient resources
- Drug Information
- Enbrel (Etanercept Prefilled Syringes)
- Enbrel (Etanercept Vials)
- Enbrel SureClick
Other brands
Erelzi, Eticovo
Professional resources
- Prescribing Information
Related treatment guides
- Rheumatoid Arthritis
- Ankylosing Spondylitis
- Psoriatic Arthritis
- Juvenile Idiopathic Arthritis
- Juvenile Rheumatoid Arthritis
- Plaque Psoriasis
ENBREL reviews – divorce or truth?
The information provided on this site is for informational purposes only and is not intended for self-treatment! Any appointments are made by a doctor, there are contraindications and adverse reactions!
What is rheumatoid arthritis?
Juvenile idiopathic arthritis is a chronic pathology, severe and progressive disease of the joints and cartilage inflammation in children and adolescents.
There are a lot of reasons for development, but they are all due to disorders of the immune system. The most likely catalyst for the development of arthritis is an infection with pathogenic strains of bacteria.
When an infection is affected, a reaction to the inflammatory process occurs and the destruction of the connective tissue, which is associated with degenerative and dystrophic disorders, is added. And if treatment is not started in a timely manner, then after degenerative destruction of cartilage tissues, there will be a complete deformation of the joints. And this already entails a limitation of the mobility of the joints and bone joints of the lower extremities of the musculoskeletal system.
What exactly causes juvenile arthritis? Most often, doctors call a genetic predisposition, infectious lesions, intoxication, joint reactions to certain drugs, chronic diseases affecting the joint cavity, and so on. With arthritis, if no drugs are used, the following symptoms may appear: painful syndrome in the joint cavity of varying intensity, edematous syndrome, redness at the site of the lesion, body temperature disturbance due to an inflammatory focus in the connective tissue, limited movement, feeling of stiffness, impossibility perform some limb manipulations and the like.
To make an accurate diagnosis and prescribe therapy, the patient must first of all consult a specialist and undergo a full course of examination. This may include: ultrasound of the joint cavity, X-ray, MRI or CT, blood tests and other types of diagnostics. All these examinations will establish a causal relationship between the occurrence of an inflammatory focus in the body, and subsequently the doctor will recommend drug therapy. It is better not to self-medicate, since there is a high probability of developing severe complications up to the complete disability of the patient.
Systemic drug therapy
As a drug therapy, the doctor may prescribe a complex treatment using various groups of drugs. For the treatment of rheumatoid arthritis, the following categories of medicines are most often used (at the discretion of the attending physician): non-steroidal anti-inflammatory drugs (NSAIDs) – are necessary to reduce pain, inflammation, and eliminate symptoms. Basic antirheumatic drugs: they are designed to eliminate inflammatory foci, soften osteoarticular decomposition (destruction of bones and joints).
Glucocorticosteroid preparations can also be recommended, which are designed to normalize metabolic processes, restore normal blood circulation in the joint cavity. Biological active agents to eliminate enzyme deficiency, to prevent decomposition and destruction of nearby tissues and articular joints. Muscle relaxants – drugs in the presence of neurological pain and disorders, substances are designed to relax skeletal muscle tissue, increase the range of motion.
Enbrel and the pharmacological properties of the drug
Enbrel is an immunosuppressive agent. What it is? Immunosuppressants are substances that suppress the human immune system, in other words, weaken it. What is it for? Most often, immunosuppressants are used as a drug in transplantology to prevent rejection of tissues and organs, in the treatment of autoimmune diseases, allergic diseases. Enbrel also falls into this category, since rheumatoid arthritis is most often caused by the causes of an autoimmune disorder.
the active substance here is: Etanercept, available in the form of a 50 mg solution and a 25 mg lyophilisate vial. this drug is an alpha cytokine inhibitor that supports the inflammatory process. By the way, with an increase in the level of alpha cytokines, which always happens with rheumatoid arthritis, it can be found in the synovial fluid in psoriatic arthritis, in the synovial fluid in ankylosing spondylitis. Therefore, the substance etanercept blocks the production of this cytokine and reduces its activity. It improves the patient’s activity, reduces the risk of complications and damage to other joint cavities.
Indications for prescribing
For which disorders is the drug prescribed? Indications are: active and progressive form of psoriatic arthritis, rheumatoid arthritis, rheumatoid arthritis monotherapy, juvenile idiopathic polyarthritis in children and adolescents, ankylosing spondylitis, psoriasis in children and adults, and so on. For full information, read the instructions or consult your doctor.
Contraindications and adverse reactions
However, Enbrel cannot be used as a stand-alone medicine, as it has contraindications and there are risks of complications. Enbrel is not recommended for use in case of hypersensitivity to the active substance, chronic infectious lesions, tuberculosis, sepsis, pregnancy, lactation, children under three years of age. It is necessary to be careful if the patient has heart failure, hepatitis, diabetes mellitus and other chronic pathologies. Most often, among the undesirable reactions from the body are: itching, fever, bleeding, subcutaneous hematoma, soreness, edematous syndrome, convulsions, bronchial asthma, rash, and the like. Be sure to tell your doctor about all the symptoms you have, if the drug brings discomfort, it is likely that either the dosage is incorrect or the drug itself is not suitable at all. Then you should think about replacing it with a similar tool.
Enbrel: how to use the medicine correctly?
The drug must be administered subcutaneously! The treatment regimen, dosage, frequency of administration, duration of the course of treatment is recommended exclusively purely individually based on the clinical data of the patient.
In each case, a personalized therapy regimen is recommended, especially for children and adolescents. The medicine must be injected subcutaneously into certain areas of the body: the anterior part of the abdominal wall, the middle part of the thigh, the outer part of the shoulder. Each time you need to inject into different places, if you inject into the same place, you must take into account the distance between them of 3 centimeters. Do not inject the medicine into scars, scars, stretch marks, red inflamed skin, painful or damaged tissue. Read the instructions for how to properly prepare the solution for use. Do not reuse the same syringe and needle, and do not use other syringes. Enbrel significantly reduces the inflammatory process in autoimmune diseases.
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| in Russian EUGIN CETROTIDE | With you I am your Hedgehog ” Health Diary” 1st administration of ENBREL — ENBREL (Etanercept) | Enbrel educational video (arabic version) | I am your hedgehog with you visao |
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The effectiveness of a new genetically engineered drug in the treatment of back pain the results of which were published in the journal
Annals of Internal Medicine injections of etanercept (a new type of genetically engineered anti-inflammatory drug) are not as effective in reducing severe pain in the back and for sciatica, as are the standard spinal steroid injections currently practiced.
This study was supervised by Dr. Steven P Cohen, Associate Professor of Anesthesiology and Critical Care at Johns Hopkins University in Baltimore, Maryland.
He opined that medical professionals have long been looking for ways to reduce pain that would be safe and reliable alternatives to steroids as a treatment for sciatica. Current treatment, in which steroids are injected into the spine, often has mixed results, and only relieves pain temporarily. The introduction of steroids also has a high potential for the development of “catastrophic complications”.
Etanercept is a genetically engineered tumor necrosis factor (FINO) inhibitor currently used to treat rheumatoid arthritis and other autoimmune disorders where the patient’s own immune system attacks the patient’s healthy tissue, causing damage, pain, and swelling.
Cohen stated that the research interest in etanercept, marketed under the trade name Enbrel, arose from attempts to relieve or reduce the pain caused by compression of a herniated disc on the roots in the lumbar or cervical spine.
The drug works by blocking tumor necrosis factor, which is produced in the body and is involved in the development of the inflammatory response. Unlike steroids, which tend to target inflammation broadly, TNF inhibitors target specific inflammatory molecules that cause pain in sciatica and other conditions. They do this by blocking nerve receptors that cannot bind to TNF molecules and should theoretically completely block pain manifestations.
However, Cohen stated, “While this new drug only offers some promise, at least at the doses that have been given (doses considered safe) the steroids still work better.”
For the blind, placebo In a controlled study, 84 adult patients with sciatica who had received epidural injections for less than 6 months were randomized to receive either 60mg of the steroid, 4mg of etanercept, or 2mL of saline.
The idea of administering epidural injections to patients with sciatica was based on the need to provide pain relief with lower dosage steroids, and thus to achieve fewer side effects compared to oral or parenteral steroids.
, since with an epidural injection there is a direct effect on the focus of inflammation in the region of the compressed root.
A long-term study was conducted at several military and civilian treatment centers. The pharmacists prepared the epidural injection syringes, while neither the doctors nor the nurses who evaluated the results knew which patients were receiving which drugs.
The results showed that one month after receiving the second of two injections, patients who received steroids reported less pain and improved ability to work than patients who received etanercept or saline placebo.
However, Cohen and his colleagues found that while the steroids worked, their effect was temporary.
Cohen notes that in another study published recently, where patients received twice the dose of etanercept, patients noted the effect lasted two weeks longer than with steroids.
These data may suggest that the effect of etanercept is negligible at low doses and that higher doses may be required, which in turn warrants further research into the potential of this new drug.