Side effect of sodium chloride. Sodium Chloride Solution: Uses, Side Effects, and Precautions for Intravenous Administration
What are the primary uses of sodium chloride solution. How is it administered intravenously. What are the potential side effects and precautions associated with its use. How should sodium chloride solution be stored and handled.
Understanding Sodium Chloride Solution and Its Medical Applications
Sodium chloride solution, commonly known as saline, is a fundamental component in medical practice. This 0.9% solution plays a crucial role in maintaining proper hydration and electrolyte balance within the body. But what exactly is this solution, and how does it function in medical settings.
Sodium chloride solution is essentially a mixture of salt and water that closely matches the concentration of sodium in human blood. This isotonic solution is primarily used to supply water and electrolytes to the body, making it an essential tool in various medical scenarios.
Key Uses of Sodium Chloride Solution
- Hydration therapy
- Electrolyte replacement
- Delivery vehicle for other medications
- Flushing of intravenous lines
- Treatment of metabolic alkalosis
Why is sodium chloride solution so versatile in medical applications. Its compatibility with human physiology makes it an ideal medium for various treatments. The solution can be used alone or as a diluent for other medications, enhancing its utility in clinical settings.
Administration and Dosage: Ensuring Proper Use of Sodium Chloride Solution
The administration of sodium chloride solution requires careful consideration and medical supervision. How is this solution typically administered to patients.
Sodium chloride solution is most commonly administered intravenously (IV). This method allows for rapid and controlled delivery of the solution directly into the bloodstream. The dosage and rate of administration are determined by several factors:
- Patient’s age
- Body weight
- Medical condition
- Individual response to treatment
Healthcare professionals carefully calculate the appropriate dosage to ensure optimal therapeutic benefit while minimizing potential risks. In some cases, patients may receive sodium chloride solution at home, but this requires proper training and guidance from medical professionals.
Preparing and Administering Sodium Chloride Solution
Before administration, it’s crucial to inspect the solution for any signs of contamination or degradation. What should you look for when examining sodium chloride solution.
- Visible particles
- Discoloration
- Cloudiness
- Leakage from the container
If any of these signs are present, the solution should not be used. Proper aseptic technique must be employed during administration to prevent infection and ensure patient safety.
Potential Side Effects: Recognizing and Managing Adverse Reactions
While sodium chloride solution is generally well-tolerated, it’s important to be aware of potential side effects. What are the most common adverse reactions associated with intravenous sodium chloride administration.
Most side effects are mild and localized to the injection site. These may include:
- Redness
- Pain
- Swelling
However, more serious side effects can occur, particularly if the solution is administered incorrectly or in excessive amounts. These may include:
- Swelling of hands, ankles, or feet
- Muscle cramps
- Unusual weakness
- Headache
- Nausea
- Extreme drowsiness
- Mental or mood changes
- Seizures
It’s crucial to report any persistent or worsening side effects to a healthcare provider promptly. In rare cases, severe allergic reactions may occur, requiring immediate medical attention.
Precautions and Contraindications: Ensuring Safe Use of Sodium Chloride Solution
Before administering sodium chloride solution, healthcare providers must consider various factors to ensure patient safety. What precautions should be taken when using this solution.
Medical history plays a crucial role in determining the appropriateness of sodium chloride solution for a patient. Particular attention should be paid to:
- Kidney problems
- Heart conditions (especially heart failure)
- Pre-existing body water or salt imbalances
- Allergies to any components of the solution
Patients should disclose all medications, including over-the-counter drugs and herbal supplements, to their healthcare provider. This information helps prevent potential drug interactions that could affect the efficacy or safety of the treatment.
Special Considerations for Pregnant and Breastfeeding Women
Is sodium chloride solution safe for use during pregnancy and breastfeeding. When used as directed, sodium chloride solution is generally considered safe for pregnant and breastfeeding women. However, it’s essential to inform healthcare providers of pregnancy or breastfeeding status to ensure appropriate monitoring and dosing.
Drug Interactions: Understanding Potential Complications
While sodium chloride solution is relatively inert, it can still interact with other medications. How can these interactions affect treatment outcomes.
Drug interactions may alter the effectiveness of medications or increase the risk of side effects. Some potential interactions include:
- Changes in the absorption or excretion of certain drugs
- Alterations in the volume of distribution of medications
- Effects on the body’s acid-base balance
To minimize the risk of adverse interactions, healthcare providers should be informed of all medications a patient is taking. This includes prescription drugs, over-the-counter medications, and herbal supplements.
Managing Potential Drug Interactions
What steps can be taken to mitigate the risk of drug interactions with sodium chloride solution. Healthcare providers may adjust dosages, alter administration schedules, or choose alternative treatments to ensure patient safety and treatment efficacy. Regular monitoring and follow-up appointments are crucial for detecting and managing any potential interactions.
Proper Storage and Handling: Maintaining the Integrity of Sodium Chloride Solution
Correct storage and handling of sodium chloride solution are essential for maintaining its effectiveness and safety. How should this solution be stored.
Sodium chloride solution should be:
- Stored at room temperature
- Protected from light and moisture
- Kept away from extreme temperatures
- Stored in its original container
It’s important to check the expiration date regularly and discard any expired solutions. Proper disposal methods should be followed to ensure environmental safety and prevent misuse.
Handling Sodium Chloride Solution in Home Settings
For patients receiving sodium chloride solution at home, what precautions should be taken. Proper training from healthcare professionals is crucial. Patients and caregivers should be instructed on:
- Aseptic technique for administration
- Proper storage conditions
- Signs of solution degradation or contamination
- Emergency procedures in case of adverse reactions
Maintaining a clean and organized storage area for medical supplies is essential for preventing contamination and ensuring easy access when needed.
Monitoring and Follow-up: Ensuring Optimal Treatment Outcomes
Regular monitoring is crucial for patients receiving sodium chloride solution, especially for extended periods. What aspects of patient health should be monitored during treatment.
Healthcare providers typically monitor:
- Fluid balance
- Electrolyte levels
- Kidney function
- Cardiovascular status
- Overall response to treatment
Laboratory tests and clinical assessments are used to evaluate these parameters and guide any necessary adjustments to the treatment plan.
Importance of Adherence to Treatment Schedule
Why is it crucial to maintain a consistent treatment schedule with sodium chloride solution. Adherence to the prescribed dosing schedule ensures that the body receives a steady supply of fluids and electrolytes, maintaining proper hydration and physiological balance. If a dose is missed or treatment is interrupted, patients should contact their healthcare provider immediately for guidance on adjusting the treatment plan.
Regular follow-up appointments allow healthcare providers to assess treatment efficacy, monitor for any developing side effects, and make necessary adjustments to the treatment regimen. These appointments also provide an opportunity for patients to discuss any concerns or questions they may have about their treatment.
Emergency Situations: Recognizing and Responding to Adverse Events
While rare, severe adverse reactions to sodium chloride solution can occur. How can patients and caregivers recognize and respond to these emergencies.
Signs of a severe allergic reaction (anaphylaxis) may include:
- Rash or hives
- Itching or swelling, especially of the face, tongue, or throat
- Severe dizziness
- Difficulty breathing
In the event of these symptoms, immediate medical attention is crucial. Patients or caregivers should call emergency services (911 in the US) without delay.
Handling Overdose Situations
What should be done in case of a suspected overdose of sodium chloride solution. If an overdose is suspected and the patient shows serious symptoms such as loss of consciousness or difficulty breathing, emergency services should be contacted immediately. For less severe cases, the local poison control center can provide guidance on appropriate actions.
It’s important to have emergency contact numbers readily available, including those for healthcare providers, poison control centers, and emergency services. Proper preparation can make a significant difference in managing unexpected adverse events effectively.
Understanding the uses, administration, potential side effects, and proper handling of sodium chloride solution is crucial for both healthcare providers and patients. By following prescribed guidelines and maintaining open communication with healthcare professionals, patients can maximize the benefits of this essential medical solution while minimizing potential risks. Regular monitoring, adherence to treatment schedules, and prompt reporting of any concerns contribute to safe and effective use of sodium chloride solution in various medical contexts.
Sodium Chloride 0.9 % Intravenous: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing
Uses
This solution is used to supply water and salt (sodium chloride) to the body. Sodium chloride solution may also be mixed with other medications given by injection into a vein.
How to use Sodium Chloride Solution, Intravenous
This solution is usually given by injection into a vein as directed by your doctor. It may be given in the hospital, in a clinic, or at home.
If you are using this product at home, learn all preparation and usage instructions from your health care professional. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. If you are mixing this solution with another medication, ask your doctor or pharmacist if it is proper to mix it with the medication. Learn how to store and discard medical supplies safely.
The dosage is based on your age, weight, medical condition, and response to treatment.
Side Effects
Redness, pain, or swelling at the injection site may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including: swelling hands/ankles/feet, muscle cramps, unusual weakness, headache, nausea, extreme drowsiness, mental/mood changes (such as confusion), seizures.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Precautions
Before using this product, tell your doctor or pharmacist if you have any allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this product, tell your doctor or pharmacist your medical history, especially of: kidney problems, heart problems (such as heart failure), body water/salt imbalance.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
This solution is safe to use during pregnancy or while breastfeeding when used as directed.
Interactions
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.
Does Sodium Chloride Solution, Intravenous interact with other drugs you are taking?
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Overdose
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.
Do not share this product with others.
Lab and/or medical tests (such as kidney function) may be done while you are using this medication. Keep all medical and lab appointments. Consult your doctor for more details.
It is important to get each dose of this medication as scheduled. If you miss a dose or if your dose is interrupted or stopped, ask your doctor right away for a new dosing schedule.
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Images
sodium chloride 0.9 % intravenous solution
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sodium chloride 0.9 % intravenous solution
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This medicine is a clear, clear, solution
sodium chloride 0.9 % intravenous solution
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This medicine is a clear, clear, solution
sodium chloride 0. 9 % intravenous solution
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This medicine is a clear, clear, solution
sodium chloride 0.9 % intravenous solution
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This medicine is a clear, clear, solution
sodium chloride 0.9 % intravenous solution
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This medicine is a clear, clear, solution
sodium chloride 0.9 % intravenous solution
Color: clearShape: Imprint:
This medicine is a clear, clear, solution
sodium chloride 0.9 % intravenous solution
Color: clearShape: Imprint:
This medicine is a clear, clear, solution
sodium chloride 0.9 % intravenous solution
Color: clearShape: Imprint:
This medicine is a clear, clear, solution
sodium chloride 0.9 % intravenous solution
Color: clearShape: Imprint:
This medicine is a clear, clear, solution
sodium chloride 0. 9 % intravenous solution
Color: clearShape: Imprint:
This medicine is a clear, clear, solution
sodium chloride 0.9 % intravenous solution
Color: clearShape: Imprint:
This medicine is a clear, clear, solution
sodium chloride 0.9 % intravenous solution
Color: clearShape: Imprint:
This medicine is a clear, clear, solution
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews
Overview
Sodium is a type of metal that is always found as a salt. The most common dietary form is sodium chloride. Sodium chloride is commonly called table salt.
Table salt accounts for 90% of dietary sodium intake in the US. Sodium helps to balance levels of fluids and electrolytes in the body. This balance can affect blood pressure and the health of the kidneys and heart.
People use sodium in the form of inhaled sodium chloride for cystic fibrosis. It is also used for low sodium levels, to prevent kidney toxicity caused by the drug amphotericin B, and for many other conditions, but there is no good scientific evidence to support many of these other uses.
Don’t confuse sodium with the sodium bicarbonate salt. These are not the same.
Uses & Effectiveness ?
Likely Effective for
- Cystic fibrosis. Using a sodium chloride inhalant long-term, along with medicine to dilate airway passages, reduces lung problems and improves quality of life in people with cystic fibrosis.
Possibly Effective for
- Kidney injury caused by an antifungal drug (amphotericin B nephrotoxicity). Giving sodium chloride solution by mouth or by IV to people receiving amphotericin B helps prevent kidney problems cause by this drug. IV products can only be given by a healthcare provider.
There is interest in using sodium for a number of other purposes, but there isn’t enough reliable information to say whether it might be helpful.
Side Effects
When taken by mouth: Sodium is likely safe for most people when used in doses less than 2.3 grams daily. In some people, sodium might increase blood pressure. Sodium is possibly unsafe when taken in doses greater than 2.3 grams daily. Larger doses might cause too much sodium to build up in the body. This might cause serious side effects including high blood pressure and heart disease.
When applied to the skin: There isn’t enough reliable information to know if sodium is safe or what the side effects might be.
When applied into the eye: There isn’t enough reliable information to know if sodium is safe or what the side effects might be.
Special Precautions and Warnings
When taken by mouth: Sodium is likely safe for most people when used in doses less than 2.3 grams daily. In some people, sodium might increase blood pressure. Sodium is possibly unsafe when taken in doses greater than 2.3 grams daily. Larger doses might cause too much sodium to build up in the body. This might cause serious side effects including high blood pressure and heart disease.
When applied to the skin: There isn’t enough reliable information to know if sodium is safe or what the side effects might be.
When applied into the eye: There isn’t enough reliable information to know if sodium is safe or what the side effects might be.
Pregnancy and breast-feeding: Sodium is likely safe to take by mouth in doses of less than 1.5 grams daily while pregnant or breast-feeding. But sodium is possibly unsafe when taken in higher amounts. Larger doses increase the risk of high blood pressure.
Children: Sodium is likely safe for most children when taken by mouth appropriately. Sodium is safe when used in doses less than 1.2 grams daily in children ages 1-3 years, 1.5 grams daily in children 4-8 years, 1.8 grams daily in children 9-13 years, and 2.3 grams daily in adolescents. Sodium is possibly unsafe when taken in higher amounts. Larger doses increase the risk of high blood pressure.
Alcohol use disorder: People who consume excessive amounts of alcohol should consume sodium in moderation. Consuming sodium can increase the risk of high blood pressure.
Heart disease: People with heart disease should consume sodium in moderation. Consuming sodium at levels above 2.3 grams daily can increase the risk of heart disease and death.
High levels of sodium in the body: Taking sodium increases levels of sodium in the body and might make this condition worse.
High blood pressure: Taking large amounts of sodium can increase blood pressure.
Kidney disease: People with kidney disease should limit sodium intake. Consuming large amounts of sodium can worsen kidney disease.
Multiple sclerosis (MS): Consuming too much salt in the diet might worsen MS. People with MS should stay below the maximum recommended amount of 2.3 grams daily.
Obesity: Obese people or those at risk for obesity should consume sodium in moderation. Consuming large amounts of sodium might cause people to gain more weight.
Weak and brittle bones (osteoporosis): Consuming too much salt in the diet might worsen osteoporosis. People with osteoporosis should stay below the maximum recommended amount of 2.3 grams daily.
Interactions ?
Increasing sodium intake might increase how much lithium is removed from the body. But reducing sodium intake might reduce how much lithium is removed from the body. People taking lithium should avoid making large changes to their intake of sodium without first talking with a healthcare professional.
Large amounts of sodium might increase blood pressure. Taking large amounts of sodium might reduce the effects of blood pressure medications. Monitor your blood pressure closely.
Some medications affect salt and water balances in the body. These medications might increase levels of sodium. Taking these medications along with sodium might cause sodium levels to become too high.
Tolvaptan is a medicine used to increase sodium levels in some people. Taking tolvaptan along with sodium might cause sodium levels to become too high.
Taking sodium with medications that contain large amounts of sodium might result in intakes that are possibly unsafe. In some people, this might cause sodium levels in the blood to become too high.
Moderate Interaction
Be cautious with this combination
Dosing
Sodium helps to balance levels of fluids and electrolytes in the body. It’s recommended that adults 19 years and older, including those pregnant and breast-feeding, consume 1.5 grams daily. Adults shouldn’t consume more than 2.3 grams daily. Recommended amounts for children depend on age. Speak with a healthcare provider to find out what dose might be best for a specific condition.
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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.
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💊 Composition of the drug Sodium chloride ✅ Use of the drug Sodium chloride Save to yourself Search for analogues Description of the active ingredients of the preparation Sodium chloride The scientific information provided is general and cannot be used to make decisions. Update date: 2022.03.24 Marketing authorization holder: PROMOMED RUS, OOO Manufactured:BIOCHEMIK JSC (Russia) ATX code: V07AB (Solvents and thinners, including irrigation solutions) Active substance: Ph. Eur. European Pharmacopoeia Dosage form
Release form, packaging and composition |
E86 | Decreased fluid volume (including dehydration, hypovolemia) |
E87. 1 | Hypoosmolarity and hyponatremia |
E87.8 | Other disorders of fluid and salt balance, not elsewhere classified |
Z51.4 | Preparatory procedures for subsequent treatment or examination, not elsewhere classified |
Dosing regimen
The route of administration and dosing regimen of a particular drug depends on its form of release and other factors. The optimal dosage regimen is determined by the doctor. Compliance of the dosage form of a particular drug with indications for use and dosing regimen should be strictly observed.
Individual, depending on the indications, the clinical situation, the therapy regimen and the dosage form used.
Isotonic sodium chloride solution is injected intravenously, s / c and in enemas, and is also used to wash wounds, eyes, nasal mucosa. Depending on the clinical situation, up to 3 l / day is administered intravenously.
Hypertonic sodium chloride solution is administered intravenously. A single dose for intravenous jet administration can be 10-30 ml. In conditions requiring immediate replenishment of sodium and chlorine ions, it is administered intravenously in a dose of 100 ml.
Side effect
Possible: nausea, vomiting, diarrhea, stomach cramps, thirst, watery eyes, sweating, fever, tachycardia, arterial hypertension, impaired renal function, edema, shortness of breath, headache, dizziness, restlessness, weakness, twitching and muscle hypertonicity.
With external and topical application of adverse reactions have not been established to date.
Contraindications for use
Hypersensitivity to sodium chloride; hypernatremia, states of hyperhydration, the threat of pulmonary edema, brain.
Use in pregnancy and lactation
In pregnancy and lactation, use may be indicated when the intended benefit to the mother outweighs the potential risk to the fetus or infant.
Use in impaired renal function
Use caution in large volumes of sodium chloride in patients with impaired renal excretory function.
Use in children
May be used in children according to indications in recommended doses and dosage forms according to age.
Special instructions
Use with caution large volumes of sodium chloride in patients with impaired renal excretory function, with hypokalemia. The introduction of large amounts of solution can lead to chloride acidosis, hyperhydration, increased excretion of potassium from the body.
Do not use hypertonic solution SC and IM.
Long-term use requires monitoring of plasma electrolyte concentrations and daily diuresis.
The temperature of the infusion solution should be 38°C.
Drug interactions
NSAIDs, androgens, estrogens, anabolic hormones, corticotropin, mineralocorticoids, vasodilators, ganglioblockers lead to increased Na retention + .
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Sodium chloride . Description of the drug in the reference book Vidal.
Sodium chloride solution: instructions for use, indications
Clear colorless solution.
Per ampoule:
active substance: sodium chloride – 18 mg;
excipient – water for injection.
Salt solutions.
ATS code: B05CB01.
Sodium and chloride ions are the most important inorganic components of the extracellular fluid, maintaining the appropriate osmotic pressure of blood plasma and extracellular fluid. Isotonic to human plasma.
Dissolution and dilution of drugs.
Before using the drug sodium chloride, a solvent for the preparation of dosage forms for injection for dissolving and diluting drugs, you must read the instructions for use of these drugs. Apply intravenously, intramuscularly, subcutaneously, depending on the method of administration of the main drug. Also applied externally and locally.
In the process of preparing dosage forms using sodium chloride, a solvent for preparing dosage forms for injection, it is necessary to follow the rules of asepsis (opening ampoules, filling a syringe or other containers with drugs).
The amount of sodium chloride, a solvent for the preparation of dosage forms for injection, is selected based on the required concentration of the dissolved / diluted drug or electrolyte concentrate.
Intravenously administered in a volume of 5-10 ml. With intramuscular and subcutaneous administration, the volume of sodium chloride solution varies depending on the drug being dissolved and the route of administration (1-5 ml). Before use, the sodium chloride solution is recommended to be heated to a temperature of 36-38 ° C.
When using isotonic sodium chloride solution as a solvent and diluent for drugs, side effects are rare.
When using the drug may develop acidosis, hyperhydration, hypokalemia. Unwise intravenous administration of sodium chloride solution (for example, to postoperative patients and patients with impaired cardiac or renal function) can lead to hypernatremia, which in turn leads to a decrease in intracellular volume and, as a result, dehydration of internal organs, especially the brain, which can lead to thrombosis and bleeding. Common side effects of excess sodium chloride in the body are: nausea, vomiting, diarrhea, abdominal pain, thirst, decreased secretion of saliva and lacrimal fluid, sweating, fever, arterial hypotension, tachycardia, impaired renal function, peripheral and pulmonary edema, stop breathing, headache, dizziness, restlessness, irritability, weakness, muscle twitching and rigidity, convulsions, coma and death. An increase in chloride levels can lead to loss of bicarbonates with an acidifying effect.
Subcutaneous administration: any addition to isotonic saline can make it hypertonic, which can cause pain at the injection site.
Unwanted action message
Tell your doctor if you have any side effects. This also applies to any side effects that are not listed in this leaflet. You can also report adverse reactions to information database on adverse reactions (actions) to drugs, including reports of ineffectiveness of drugs, identified in the territory of the state (UE Center for Expertise and Testing in Public Health M3 RB, rceth.by ). By reporting adverse reactions, you help to get more information about the safety of the drug.
Incompatibility of the main drug and isotonic sodium chloride solution 9mg / ml, hypernatremia, acidosis, hyperchloremia, hypokalemia, extracellular overhydration; circulatory disorders threatening swelling of the brain and lungs; cerebral edema, pulmonary edema, acute LV insufficiency, concomitant administration of corticosteroids in high doses.
With the introduction of the recommended volumes of sodium chloride solution, an overdose is unlikely. In large quantities, it can lead to the development of chloride acidosis, increased elimination of potassium (hypokalemia), and hyperhydration.
Large volumes of isotonic sodium chloride solution are used with caution in patients with chronic renal failure (oligoanuria), chronic heart failure, and hypokalemia.
Do not use solutions with physical properties that have changed during dissolution.
Before dissolving the drug, it should be checked whether it is possible to use Sodium chloride, solution for injection, isotonic 9 mg / ml, to dissolve / dilute this drug.
Use the drug immediately after opening the ampoule or after preparing ready-to-use dosage forms.
Ampoules for single use only. The remaining unused volumes of the drug are subject to destruction.
Use the solution only if it is clear and the ampoule is not damaged.
From the point of view of microbiological safety, ready-to-use dosage forms obtained by dilution / dilution with sodium chloride, a solvent for the preparation of dosage forms for injection in compliance with aseptic rules, should be used immediately.
The effect on the ability to drive vehicles and mechanisms is determined by the instructions for the drug, for the dissolution / dilution of which sodium chloride is used, a solvent for the preparation of dosage forms for injection.
Use during pregnancy and during breastfeeding is determined by the instructions for the drug, for the dissolution / dilution of which sodium chloride, a solvent for the preparation of dosage forms for injection, will be used.
Use in accordance with the instructions for medical use of the main medicinal product. When mixed with other medicinal products, compatibility must be checked visually (however, invisible and therapeutic incompatibilities are possible).
2 ml in ampoules. 10 ampoules, together with instructions for use, are placed in a box. 5 ampoules are placed in a blister pack, 1 or 2 blister packs, together with instructions for use, are placed in a pack.
Store at a temperature not exceeding 25 °C.