What are the side effects of acebutolol? How should this medication be used? What special precautions should be followed? Get the answers to these and other questions about acebutolol.

Understanding Acebutolol: What is it and How Does it Work?

Acebutolol is a medication that belongs to a class of drugs known as beta blockers. It is primarily used to treat high blood pressure (hypertension) and irregular heart rhythms (arrhythmia). Acebutolol works by relaxing blood vessels and slowing the heart rate, which ultimately improves blood flow and decreases blood pressure.

Acebutolol: Approved Uses and Off-Label Applications

Acebutolol is approved for the treatment of high blood pressure and irregular heartbeats. However, it may also be used off-label to treat certain types of chest pain (angina). It is important to discuss with your doctor the potential risks and benefits of using acebutolol for your specific condition.

Dosage and Administration of Acebutolol

Acebutolol is available in capsule form and is typically taken once or twice a day, as directed by your healthcare provider. It is essential to follow the instructions on your prescription label carefully and to take the medication as prescribed, without skipping doses or taking more than recommended.

Potential Side Effects of Acebutolol

Like any medication, acebutolol can cause side effects. Some common side effects include dizziness, lightheadedness, fatigue, headache, constipation, diarrhea, and upset stomach. More serious side effects, such as shortness of breath, swelling of the feet and lower legs, and chest pain, should be reported to your doctor immediately.

Precautions and Interactions with Acebutolol

Before taking acebutolol, it is important to inform your doctor and pharmacist about any allergies, medical conditions, or other medications you are currently taking. Certain conditions, such as heart, kidney, or liver disease, as well as asthma or other lung diseases, may require special consideration when using acebutolol.

Storing and Disposing of Acebutolol

Acebutolol should be stored in its original container, kept tightly closed, and out of reach of children. It should be kept at room temperature and away from excessive heat and moisture. Proper disposal of unused or expired medication is important to prevent potential misuse or environmental contamination.

Frequently Asked Questions about Acebutolol

What is the purpose of taking acebutolol?
Acebutolol is primarily used to treat high blood pressure and irregular heartbeats. It can also be used off-label to treat certain types of chest pain (angina).

How often should I take acebutolol?
Acebutolol is typically taken once or twice a day, as directed by your healthcare provider. It is important to take the medication as prescribed and not to skip doses or take more than recommended.

What are the potential side effects of acebutolol?
Common side effects of acebutolol include dizziness, lightheadedness, fatigue, headache, constipation, diarrhea, and upset stomach. More serious side effects, such as shortness of breath, swelling of the feet and lower legs, and chest pain, should be reported to your doctor immediately.

Are there any special precautions I should take when using acebutolol?
Before taking acebutolol, it is important to inform your doctor and pharmacist about any allergies, medical conditions, or other medications you are currently taking. Certain conditions, such as heart, kidney, or liver disease, as well as asthma or other lung diseases, may require special consideration when using acebutolol.

How should I store and dispose of acebutolol?
Acebutolol should be stored in its original container, kept tightly closed, and out of reach of children. It should be kept at room temperature and away from excessive heat and moisture. Proper disposal of unused or expired medication is important to prevent potential misuse or environmental contamination.

Can I drink alcohol while taking acebutolol?
Alcohol can add to the drowsiness caused by acebutolol, so it is generally recommended to avoid or limit alcohol consumption while taking this medication.

What should I do if I forget to take a dose of acebutolol?
If you forget to take a dose of acebutolol, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Acebutolol: MedlinePlus Drug Information

pronounced as (a se byoo’ toe lole)

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Acebutolol is used to treat high blood pressure. Acebutolol also is used to treat an irregular heartbeat. Acebutolol is in a class of medications called beta blockers. It works by relaxing blood vessels and slowing heart rate to improve blood flow and decrease blood pressure.

High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.

Acebutolol comes as a capsule to take by mouth. It usually is taken once or twice a day. To help you remember to take acebutolol, take it around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take acebutolol exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Acebutolol controls your condition but does not cure it. Continue to take acebutolol even if you feel well. Do not stop taking acebutolol without talking to your doctor. If you suddenly stop taking acebutolol, you may experience serious heart problems such as angina (chest pain) or heart attack.

Acebutolol is also used sometimes to treat chest pain (angina). Talk to your doctor about the possible risks of using this medication for your condition.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking acebutolol,

• tell your doctor and pharmacist if you are allergic to acebutolol, any other medications, or any ingredients in acebutolol capsules. Ask your pharmacist for a list of the ingredients.
• tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: medications for migraine headaches, diabetes, asthma, allergies, colds, or pain; other medications for high blood pressure or heart disease; and reserpine.
• tell your doctor if you have or have ever had heart, kidney, or liver disease; asthma or other lung diseases; diseases of the blood vessels; severe allergies; diabetes; or hyperthyroidism (an overactive thyroid gland).
• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking acebutolol, call your doctor.
• if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking acebutolol.
• you should know that this medication may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.
• remember that alcohol can add to the drowsiness caused by this medication.

Unless your doctor tells you otherwise, continue your normal diet.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Acebutolol may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• dizziness
• lightheadedness
• excessive tiredness
• headache
• constipation
• diarrhea
• upset stomach
• muscle aches

Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately:

• shortness of breath or wheezing
• swelling of the feet and lower legs
• chest pain

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA’s Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can’t be awakened, immediately call emergency services at 911.

• Sectral^®

Last Revised – 10/15/2017

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Acebutolol Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Uses

Acebutolol is used to treat high blood pressure and irregular heartbeat (arrhythmia). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Treating irregular heartbeat helps the heart work better and with less strain. Irregular heartbeats can be serious and may sometimes even lead to a heart attack.This medication belongs to a class of drugs known as beta blockers. It works by blocking the action of certain natural substances in your body, such as epinephrine, on the heart and blood vessels. This effect lowers heart rate, blood pressure, and strain on the heart.

How to use Acebutolol HCL

See also Warning section.

Take this medication by mouth with or without food as directed by your doctor, usually once or twice daily. The dosage is based on your medical condition and response to treatment.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.

For the treatment of high blood pressure, it may take several weeks before you get the full benefit of this drug. Keep taking this medication even if you feel well. Most people with high blood pressure do not feel sick.

Tell your doctor if your condition does not improve or if it worsens (for example, if your routine blood pressure readings remain high or increase).

Side Effects

See also Warning and Precautions sections.

Tiredness, dizziness, lightheadedness, nausea, upset stomach, slow heartbeat, or trouble sleeping may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

This drug may reduce blood flow to your hands and feet, causing them to feel cold. Smoking may worsen this effect. Dress warmly and avoid tobacco use.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: symptoms of asthma (for example, feelings of tightness in the chest, shortness of breath, cough, wheezing), blue fingers/toes, fainting, very slow heartbeat, new or worsening symptoms of heart failure (such as shortness of breath, swelling ankles/feet, unusual tiredness, unusual/sudden weight gain), mental/mood changes (such as confusion, depression, memory problems), vision changes, symptoms of liver disease (such as nausea that doesn’t stop, dark urine, vomiting, stomach/abdominal pain, yellowing eyes/skin).

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking acebutolol, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood circulation problems (such as Raynaud’s disease, peripheral vascular disease), breathing problems (such as asthma, chronic bronchitis, emphysema), heart problems (such as heart failure, previous heart attack, heart rhythm problems), kidney problems, liver problems, mental/mood disorders (such as depression), a certain muscle disease (myasthenia gravis), overactive thyroid disease (hyperthyroidism), serious allergic reactions, including those needing treatment with epinephrine.

This drug may make you dizzy. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

This product may prevent the fast/pounding heartbeat you would usually feel when your blood sugar level falls too low (hypoglycemia). The risk is higher if you have diabetes, or are vomiting, fasting, or not eating regularly. Other symptoms of low blood sugar level, such as dizziness and sweating, are not affected by this drug.

If you have diabetes, this product may make it harder to control your blood sugar levels. Check your blood sugar levels regularly as directed by your doctor. Tell your doctor right away if you have symptoms of high blood sugar such as increased thirst/urination. Your doctor may need to adjust your diabetes medication, exercise program, or diet.

Children may be at greater risk for low blood sugar (hypoglycemia) while using this drug, especially if they are vomiting or not eating regularly. To help prevent low blood sugar, make sure children eat regularly. If your child cannot eat regularly, is vomiting, or has symptoms of low blood sugar (such as sweating, shaking), tell the doctor right away.

During pregnancy, this medication should be used only when clearly needed. Babies born to mothers taking this drug during pregnancy may have a low birth weight and require monitoring for problems such as low blood pressure and slow heartbeat. Discuss the risks and benefits with your doctor.

This drug passes into breast milk. Consult your doctor before breast-feeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

A product that may interact with this drug is: fingolimod.

Some products have ingredients that could raise your heart rate or blood pressure. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen).

Does Acebutolol HCL interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: unusually slow heartbeat, fainting, severe weakness.

Do not share this medication with others.

Lifestyle changes such as stress reduction programs, exercise, and dietary changes may increase the effectiveness of this medicine. Talk to your doctor or pharmacist about lifestyle changes that might benefit you.

Check your blood pressure and pulse (heart rate) regularly while taking this medication. Learn how to check your blood pressure and pulse at home, and share the results with your doctor.

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Images

acebutolol 400 mg capsule

Color: bright orange,lavenderShape: oblongImprint: AMNEAL 670

This medicine is a bright orange lavender, oblong, capsule imprinted with “AMNEAL” and “670”.

acebutolol 400 mg capsule

Color: maroon,greenShape: oblongImprint: ANI 256

This medicine is a bright orange lavender, oblong, capsule imprinted with “AMNEAL” and “670”.

acebutolol 200 mg capsule

Color: red,grayShape: oblongImprint: ANI 255

This medicine is a bright orange lavender, oblong, capsule imprinted with “AMNEAL” and “670”.

acebutolol 200 mg capsule

Color: bright orange,lavenderShape: oblongImprint: Amneal 669

This medicine is a bright orange lavender, oblong, capsule imprinted with “AMNEAL” and “670”.

acebutolol 400 mg capsule

Color: medium orangeShape: oblongImprint: MYLAN 1400 MYLAN 1400

This medicine is a bright orange lavender, oblong, capsule imprinted with “AMNEAL” and “670”.

acebutolol 200 mg capsule

Color: medium orangeShape: oblongImprint: MYLAN 1200 MYLAN 1200

This medicine is a bright orange lavender, oblong, capsule imprinted with “AMNEAL” and “670”.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

Acebutolol – description of the substance, pharmacology, use, contraindications, formula

Contents

• Structural formula

• Russian name

• English name

• Latin name

• chemical name

• Gross formula

• Pharmacological group of the substance Acebutolol

• Nosological classification

• CAS code

• pharmachologic effect

• Characteristic

• Pharmacology

• Application of the substance Acebutolol

• Contraindications

• Application restrictions

• Use during pregnancy and lactation

• Side effects of the substance Acebutolol

• Interaction

• Overdose

• Dosage and administration

• Precautionary measures

• special instructions

Structural formula

Russian name

Acebutolol

English name

Acebutolol

Latin name

Acebutololi)

Chemical name

(±)-N-[3-Acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]butanamide (as hydrochloride)

Gross formula

C ₁₈ H ₂₈ N ₂ O ₄

Pharmacological group of the substance Acebutolol

Beta blockers

Nosological classification

ICD-10 code list

• I10 Essential (primary) hypertension

• I15 Secondary hypertension

• I20 Angina pectoris [angina pectoris]

• I25 Chronic ischemic heart disease

• I47. 1 Supraventricular tachycardia

• I47.2 Ventricular tachycardia

• I48 Atrial fibrillation and flutter

• I49.4 Other and unspecified premature depolarization

• R07. 2 Pain in the region of the heart

CAS code

37517-30-9

Pharmacological action

Pharmacological action –

antianginal , antiarrhythmic , hypotensive .

Characteristics

White or almost white powder. Let’s well dissolve in water, less – in alcohol.

Pharmacology

Blocks beta ₁ -adrenergic receptors, has its own sympathomimetic activity and membrane stabilizing properties. Normalizes increased SBP and diastolic blood pressure while maintaining heart rate and cardiac output. Hypotension develops 1.5 hours after administration, reaches a maximum after 3-8 hours, lasts up to 24-30 hours and stabilizes by the end of 2 weeks of treatment. The antihypertensive effect is due to CNS depression, a decrease in cardiac output, renin synthesis and activity, restoration of baroreceptor sensitivity and, as a result, a decrease in peripheral sympathetic influences. Antiarrhythmic properties are associated with the suppression of the automatism of the sinus node, the lengthening of the duration of the refractory period, and the slowing down of the AV node. Does not have a negative effect on lipid metabolism.

In experimental studies with the introduction of acebutolol in doses up to 300 mg / kg / day (15 MRDA) and diacetolol in doses up to 1800 mg / kg / day, no signs of carcinogenicity were found in rats and mice. The Ames test for mutagenicity was negative. In male and female rats, when using doses of acebutolol up to 240 mg / kg / day and diacetolol 1000 mg / kg / day, no adverse effect on fertility was noted, in rats and rabbits, doses up to 31.5 and 6.8 times, respectively, exceeding the MRDC, teratogenic no action was taken; acebutolol at a dose of 135 mg/kg/day retarded fetal growth, and diacetolol (450 mg/kg/day) increased post-implantation mortality in rabbits.

Almost completely (97%) absorbed from the gastrointestinal tract (food intake slows down absorption). Bioavailability is about 40%, since it undergoes intensive biotransformation during the “first pass” through the liver, where it is partially converted into a more active metabolite – diacetolol. The bioavailability of acebutolol is increased by 2 times in the elderly, due to a decrease in metabolism during the “first pass” through the liver and a weakening of kidney function. max “> C _max acebutolol is reached after 2.5 hours, diacetolol – after 3.5 hours. In the blood, acebutolol (26%), diacetolol (6–9%) are associated with proteins. T _1/2 – 12 hours and 16 hours, respectively (with renal failure 1/2 “> T _1/2 diacetolol lengthens 2-3 times). Acebutolol and diacetolol pass through histohematic barriers, incl. placental, passes into breast milk Excreted by the kidneys – 30-40% (mainly diacetolol) and the gastrointestinal tract – 50-60% (acebutolol)

Use of the substance Acebutolol

ventricular tachyarrhythmia, atrial fibrillation, hypertrophic cardiomyopathy, mitral valve prolapse, vascular headache, tremor, anxiety, thyrotoxicosis.

Contraindications

Chronic heart failure in the stage of decompensation, cardiogenic shock, sick sinus syndrome, II and III degree AV block, severe bradycardia (less than 50 bpm), hypotension (including myocardial infarction) .

Restrictions for use

Bronchial asthma, obstructive airway disease, liver or kidney dysfunction, peripheral vascular disease (Raynaud’s disease or others), heart failure (decompensated stage), pheochromocytoma, diabetes mellitus, hyperthyroidism, depression, myasthenia gravis, psoriasis, pregnancy, breastfeeding, old age and childhood.

Use during pregnancy and lactation

Possible if the expected effect of therapy outweighs the potential risk to the fetus. At the time of treatment should stop breastfeeding.

Side effects of the substance Acebutolol

From the side of the nervous system and sensory organs: sleep disturbance (11%), insomnia (6%), dizziness (6%), headache (6%), drowsiness (3%), nightmares (2%), depression (2%), blurred vision (2%), asthenia, weakness, anxiety, paresthesia, convulsions, decreased production of lacrimal fluid (dryness of the mucous membrane of the eyes), eye pain.

From the side of the cardiovascular system and blood (hematopoiesis, hemostasis): chest pain (2%), deterioration of peripheral circulation, decompensation of heart failure, AV blockade, bradycardia, hypotension.

From the digestive tract: dyspepsia (4%), diarrhea (4%), constipation (4%), nausea (4%), flatulence (3%), anorexia, hyperlipidemia, liver dysfunction (increased LDH, bilirubin, alkaline phosphatases, and other enzymes).

From the respiratory system: shortness of breath (4%), vasomotor rhinitis (2%), cough (1%), bronchospasm, status asthmaticus (rarely).

From the genitourinary system: edema (2%), dysuric disorders, dark urine, nocturia, weakening of libido.

Other: allergic reactions (rash – 2%), arthralgia and myalgia (2%), hypoglycemia.

Interaction

Verapamil, diltiazem, quinidine, halogenated anesthetics, amiodarone increase the negative ino- and/or chronotropic effect. Hypotension is potentiated by other antihypertensive drugs. Accelerates the depletion of catecholamine depots against the background of sympatholytics (reserpine). With the simultaneous use of insulin and oral antidiabetic drugs, it increases the symptoms of hypoglycemia. Incompatible with MAO inhibitors. Increases the likelihood of severe systemic reactions (up to anaphylaxis) against the background of the use of allergens (immunotherapy, skin tests).

Overdose

Symptoms: severe bradycardia, arterial hypotension, bronchospastic reactions, heart failure.

Treatment: symptomatic: atropine (IV 1–3 mg), glucagon, vasopressors (dobutamine, epinephrine, dopamine), isoprenaline, diazepam, bronchodilators (theophylline, aminophylline, terbutaline), cardiac glycosides, diuretics ; performing hemodialysis.

Dosage and Administration

Int. For hypertension – 400 mg in 1-2 doses (morning and evening), maintenance dose – 400-800 mg, for angina pectoris – 200 mg 2 times a day, if ineffective – 300 mg 3 times a day . In case of impaired renal function dose depends on creatinine Cl: with Cl less than 50 ml / min / 1.73 m ² not more than 50% of the usual dose, below 25 ml / min / 1.73 m ² – 25% usual dose; for elderly patients, the maximum allowable dose is 800 mg.

Precautions

Cardiac failure should be compensated before starting treatment, followed by monitoring of heart rate, blood pressure and early detection of symptoms of heart failure. It is necessary to reduce doses in elderly patients, in the presence of obstructive respiratory diseases, bradycardia. With pheochromocytoma, the appointment is possible only in combination with an alpha-blocker. It should be borne in mind that in patients with diabetes during treatment, hypoglycemia is not accompanied by tachycardia. Reception of acebutolol is possible 2 weeks after the abolition of MAO inhibitors. During treatment, it is necessary to exclude the use of alcoholic beverages (risk of developing orthostatic hypotension). When performing surgery using general anesthesia, the anesthetic with the least negative inotropic effect should become the means of choice.

Acebutolol should be discontinued gradually, over a period of at least 2 weeks, as sudden cessation can cause severe arrhythmia, myocardial infarction. Pediatric use should be avoided as the safety and efficacy of its use in children have not been determined. Use with caution during work for drivers of vehicles and people whose profession is associated with increased concentration of attention.

Special instructions

During treatment, changes in the results of tests during laboratory tests (increase in the titer of antinuclear antibodies, etc.) are possible.

Sektral – instructions for use, doses, side effects, reviews of the drug Sektral: – Encyclopedia of drugs RLS

Description of the drug Sektral (coated tablets, 200 mg) is based on official instructions, approved by the manufacturer in 2002

Approval date: 07/31/2002

Content

• Active substance
• ATX
• Pharmacological group
• Nosological classification (ICD-10)
• Composition and form of release
• pharmachologic effect
• pharmachologic effect
• Pharmacodynamics
• Indications
• Contraindications
• Use during pregnancy and lactation
• Dosage and administration
• Side effects
• Interaction
• Precautionary measures
• Storage conditions
• Best before date
• Reviews

Active ingredient

Acebutolol* (Acebutolol*)

ATX

C07AB04 Acebutolol

Pharmacological group

Beta blockers

Nosological classification (ICD-10)

ICD-10 code list

• I10 Essential (primary) hypertension
• I15 Secondary hypertension
• I20 Angina pectoris [angina pectoris]
• I48 Atrial fibrillation and flutter
• I49. 9 Unspecified cardiac arrhythmia

Composition and formulation

1 coated tablet contains acebutolol (as hydrochloride) 200 mg; 10 pcs in a blister, 2 blisters in a cardboard box.

Pharmacological action

Pharmacological action –

antiarrhythmic , antianginal , hypotensive .

Selectively blocks beta-adrenergic receptors of the heart, has internal sympathomimetic activity and membrane stabilizing effect.

Selectively blocks beta-adrenergic receptors of the heart, has internal sympathomimetic activity and membrane stabilizing effect.

Pharmacodynamics

Inhibits excitability and conduction in the myocardium. It has a slight negative inotropic effect, slightly reduces the minute output.

Indications

Arrhythmia, incl. atrial fibrillation, angina pectoris, arterial hypertension.

Contraindications

II and III degree AV blockade, bradycardia, congestive heart failure, bronchial asthma, taken 24-48 hours before anesthesia, simultaneous use of MAO inhibitors, pregnancy (I trimester).

Use during pregnancy and lactation

Contraindicated during pregnancy (I trimester).

Dosage and administration

Information for healthcare professionals only.
Are you a healthcare professional?

Inside. Arterial hypertension: 400 mg once (morning) or in 2 divided doses (morning and evening).

Angina pectoris and arrhythmias: 200 mg 2 times daily, in emergency up to 300 mg 3 times daily, maintenance dose 100 mg 3 times or 200 mg 2 times daily.

Side effects

Heart failure, AV block, bradycardia, hypertension; dyspepsia, hypoglycemia, allergic reactions.

Interactions

Information for healthcare professionals only.
Are you a healthcare professional?

Enhances the hypoglycemic effect of insulin and oral antidiabetic agents.