Side effects of b12 tablets. Vitamin B-12 Supplements: Essential Benefits and Potential Side Effects
What are the main benefits of vitamin B-12 supplements. How can excessive intake lead to potential side effects. When should you consider taking B-12 supplements. What are the recommended daily allowances for different age groups.
The Crucial Role of Vitamin B-12 in Our Body
Vitamin B-12, also known as cobalamin, is a vital nutrient that plays a crucial role in various bodily functions. This water-soluble vitamin is essential for DNA synthesis, red blood cell formation, and proper neurological function. While most people obtain sufficient B-12 through their diet, some individuals may require supplements to maintain optimal levels.
How does vitamin B-12 work in our body? Once absorbed in the intestines, B-12 is utilized to produce DNA and red blood cells. Any excess vitamin is stored in the liver for future use. This storage capability allows our body to maintain a reserve of B-12, which can be tapped into during periods of low intake.
Common Sources of Vitamin B-12 in Our Diet
Vitamin B-12 is naturally found in various animal-based foods. Some of the richest sources include:
- Eggs
- Cheese
- Fish
- Shellfish
- Liver
- Kidney
- Red meat
For individuals following a plant-based diet, fortified foods and supplements are often necessary to meet B-12 requirements. Is it possible to get enough B-12 from plant sources alone? While some plant foods are fortified with B-12, it’s generally challenging to obtain adequate amounts solely from plant-based sources without supplementation.
Recommended Daily Allowances of Vitamin B-12
The National Institutes of Health has established recommended dietary allowances (RDAs) for vitamin B-12. These guidelines ensure that individuals consume sufficient amounts to maintain optimal health:
- 2.4 micrograms (mcg) daily for ages 14 years or older
- 2.6 mcg daily for pregnant women
- 2.8 mcg daily for breastfeeding women
For adults over 50 years of age, it’s recommended to obtain the RDA through B-12 fortified foods or supplements containing 25 to 100 mcg of B-12. Why is there a higher recommendation for older adults? As we age, our ability to absorb vitamin B-12 from food sources may decrease, making supplementation more necessary.
Potential Side Effects of Vitamin B-12 Supplements
While vitamin B-12 is generally safe when taken at recommended doses, excessive intake, particularly through supplements, can lead to various side effects. These may include:
- Mild diarrhea
- Itching
- Skin rash
- Headache
- Dizziness
- Nausea
- Vomiting
In rare cases, more severe side effects may occur, such as:
- Pulmonary edema and congestive heart failure early in treatment
- Vein thrombosis
- Sensation of swelling
- Polycythemia vera (a rare, slow-growing blood cancer)
Can vitamin B-12 cause allergic reactions? While extremely rare, severe allergic reactions (anaphylaxis) to B-12 supplements have been reported. Symptoms may include swelling of the face, tongue, and throat, as well as difficulty swallowing and breathing. If you experience these symptoms after taking B-12, seek immediate medical attention.
Interactions Between Vitamin B-12 and Other Medications
Certain medications can interfere with the absorption or serum levels of vitamin B-12. If you’re taking any of the following, you may need to consult your healthcare provider about B-12 supplementation:
- Colchicine
- Metformin
- Proton pump inhibitors
- Vitamin C
- Chloramphenicol
- H2 blockers
- Aminosalicylic acid
How should you take B-12 supplements if you’re on these medications? Your doctor may recommend taking B-12 supplements at a different time of day than your other medications to ensure proper absorption. For instance, you might take B-12 in the morning and other medications at night.
Special Considerations for Vitamin B-12 Supplementation
While B-12 supplements are generally safe, there are some special considerations to keep in mind:
- Pregnancy and breastfeeding: B-12 is safe to take in recommended dosages during pregnancy and while breastfeeding.
- Allergies: Avoid B-12 supplements if you have sensitivities or allergies to vitamin B-12, cobalt, or any other ingredients in the supplement.
- Folic acid interactions: Folic acid supplements may interfere with vitamin B-12. Inform your doctor if you’re taking folic acid alongside B-12.
Should you stop taking B-12 supplements if you experience side effects? If you notice any adverse effects after starting B-12 supplements, discontinue use immediately and consult your healthcare provider. They can help determine an appropriate dosage or suggest alternative ways to meet your B-12 needs.
Recognizing and Addressing Vitamin B-12 Deficiency
Vitamin B-12 deficiency can lead to various health issues, including anemia and neurological problems. Some individuals are at higher risk of deficiency, including:
- Older adults
- Vegetarians and vegans
- Individuals with gastrointestinal disorders
- Those who have undergone weight loss surgery
What are the symptoms of B-12 deficiency? Common signs include fatigue, weakness, constipation, loss of appetite, weight loss, and megaloblastic anemia. Neurological changes such as depression, confusion, poor memory, and even dementia can also occur.
How is B-12 deficiency diagnosed and treated? Diagnosis typically involves blood tests to measure B-12 levels and complete blood count. Treatment often includes oral or injectable B-12 supplements, depending on the severity of the deficiency and the individual’s ability to absorb the vitamin.
Injectable Vitamin B-12: Benefits and Risks
For individuals with severe B-12 deficiency or absorption issues, injectable vitamin B-12 may be recommended. While effective, this form of supplementation can carry additional risks and side effects, including:
- Pain or redness at the injection site
- Temporary itching or rash
- Dizziness or headache
- Anxiety or nervousness
Why might a doctor prescribe injectable B-12 over oral supplements? Injectable B-12 bypasses the digestive system, ensuring direct absorption into the bloodstream. This can be particularly beneficial for individuals with conditions that impair B-12 absorption in the gut, such as pernicious anemia or certain gastrointestinal disorders.
The Role of Vitamin B-12 in Cognitive Function and Neurological Health
Vitamin B-12 plays a crucial role in maintaining cognitive function and overall neurological health. Adequate B-12 levels are essential for:
- Myelin formation: B-12 is necessary for the production of myelin, the protective coating around nerves that facilitates proper signal transmission.
- Neurotransmitter synthesis: B-12 is involved in the production of various neurotransmitters, including serotonin and dopamine.
- Brain health: Sufficient B-12 levels may help prevent cognitive decline and reduce the risk of neurodegenerative diseases.
Can B-12 supplementation improve cognitive function in older adults? Some studies suggest that B-12 supplementation may help improve cognitive function in older adults with low B-12 levels. However, more research is needed to fully understand the relationship between B-12 and cognitive health.
B-12 and Mood Disorders
There is growing evidence suggesting a link between vitamin B-12 deficiency and mood disorders, particularly depression. B-12 is involved in the production of S-adenosylmethionine (SAM), a compound that plays a role in the synthesis of neurotransmitters that regulate mood.
How might B-12 supplementation affect individuals with depression? While B-12 supplementation alone is not a cure for depression, addressing B-12 deficiency in individuals with depression may help improve symptoms and enhance the effectiveness of antidepressant medications.
Vitamin B-12 and Cardiovascular Health
Vitamin B-12, along with other B vitamins, plays a role in maintaining cardiovascular health. B-12 is involved in:
- Homocysteine regulation: B-12 helps convert homocysteine, an amino acid associated with increased risk of heart disease when levels are elevated, into methionine.
- Red blood cell production: Adequate B-12 levels ensure proper red blood cell formation, which is crucial for oxygen transport throughout the body.
- Arterial health: Some studies suggest that B-12 may help maintain the health of arterial walls.
Does B-12 supplementation reduce the risk of cardiovascular disease? While maintaining adequate B-12 levels is important for overall health, current evidence doesn’t conclusively show that B-12 supplementation alone reduces the risk of cardiovascular disease in individuals with normal B-12 levels.
B-12 and Anemia Prevention
Vitamin B-12 deficiency can lead to a type of anemia called megaloblastic anemia, characterized by the production of abnormally large, immature red blood cells. Symptoms of this condition include:
- Fatigue and weakness
- Shortness of breath
- Pale or yellowish skin
- Irregular heartbeats
- Weight loss
- Numbness or tingling in hands and feet
How quickly can B-12 supplementation resolve anemia? With proper B-12 supplementation, blood cell counts typically begin to improve within days to weeks. However, full resolution of symptoms may take several months, especially if neurological complications have developed.
The Future of Vitamin B-12 Research and Supplementation
As our understanding of vitamin B-12’s role in human health continues to evolve, researchers are exploring new areas of potential benefit and improved supplementation methods. Some current areas of interest include:
- Nasal gel formulations: Researchers are developing B-12 nasal gels as an alternative to injections for individuals with absorption issues.
- Sublingual supplements: These under-the-tongue supplements may offer improved absorption compared to traditional oral tablets.
- Fortification of plant-based foods: As plant-based diets gain popularity, there’s increased interest in developing more effective methods of fortifying plant foods with B-12.
- Personalized supplementation: Advances in genetic testing may lead to more tailored B-12 supplementation recommendations based on individual needs and absorption capabilities.
What potential benefits of vitamin B-12 are currently being studied? Ongoing research is exploring the potential role of B-12 in areas such as cancer prevention, immune function enhancement, and management of neurodegenerative diseases. However, more studies are needed to confirm these potential benefits.
The Importance of Regular B-12 Monitoring
Given the crucial role of vitamin B-12 in numerous bodily functions and the potential risks associated with both deficiency and excessive intake, regular monitoring of B-12 levels is important, especially for at-risk individuals. This may include:
- Older adults
- Individuals following strict vegetarian or vegan diets
- Those with gastrointestinal disorders or who have undergone gastrointestinal surgeries
- Individuals taking medications that may interfere with B-12 absorption
How often should B-12 levels be checked? The frequency of B-12 testing can vary depending on individual risk factors and health status. For most healthy adults, a B-12 test every 2-3 years may be sufficient, while those at higher risk may require more frequent monitoring. Always consult with your healthcare provider to determine the appropriate testing schedule for your specific needs.
In conclusion, vitamin B-12 is an essential nutrient with wide-ranging effects on our health. While dietary sources are typically sufficient for most individuals, supplementation may be necessary for certain populations. As with any supplement, it’s crucial to be aware of potential side effects and interactions. By understanding the benefits and risks associated with vitamin B-12, individuals can make informed decisions about their nutritional needs and work with healthcare providers to maintain optimal B-12 levels for overall health and well-being.
Vitamin B-12 Side Effects
Vitamin B-12 Side Effects
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Medically reviewed by Jared Meacham, Ph. D., RD, PMP, MBA, CSCS — By Emily Cronkleton — Updated on June 8, 2023
Your doctor will give you the right dosage of vitamin B-12 supplement, especially if you will inject it. Taking too much can cause side effects like nausea, headache, dizziness, and in rarely, blood clots or cancer.
Everyone needs vitamin B-12, and most people get enough through their diet. However, it’s important to know what side effects occur when you take too much.
Vitamin B-12 is water-soluble and absorbed in the intestines. After it’s absorbed, it’s used to make DNA and red blood cells. Vitamin B-12 that isn’t being used is stored in the liver. But if you take supplements, you might ingest more than your body needs.
Oral vitamin B-12 is safe to take at recommended doses for healthy people.
Injectable vitamin B-12, which is used to treat significant deficiencies, can cause the following side effects:
- mild diarrhea
- itching
- skin rash
- headache
- dizziness
- nausea
- vomiting
- pulmonary edema and congestive heart failure early in treatment
- vein thrombosis
- sensation of swelling
- polycythemia vera (rare, slow growing blood cancer)
Vitamin B-12 can cause very rare but serious allergic reactions (anaphylaxis). This includes swelling of the face, tongue, and throat, and difficulty swallowing and breathing. If this occurs after you take vitamin B-12, call 911 or your local emergency services immediately.
Some agents are linked to reduced absorption or serum levels of vitamin B-12. You may need vitamin B-12 supplements if you take any of the following:
- colchicine
- metformin
- proton pump inhibitors
- vitamin C
- chloramphenicol
- h3 blockers
- aminosalicylic acid
Folic acid supplements may interfere with vitamin B-12. Be sure to tell your doctor if you take folic acid.
You may need to take vitamin B-12 separately from the above drugs and supplements — say, one in the morning and one at night — so you can get the full dose of vitamin B-12.
Don’t take vitamin B-12 supplements if you have sensitivities or allergies to vitamin B-12, cobalt, and any other ingredients. Vitamin B-12 is safe to take in recommended dosages if you’re pregnant or breastfeeding.
If you notice any adverse effects after you start taking vitamin B-12 supplements, you should discontinue use immediately. Seek medical attention if your symptoms get worse or are severe.
You can consult your doctor to establish an appropriate dose if it’s determined that you don’t get enough B-12 from food sources.
According to the National Institutes of Health, the recommended dietary amounts (RDAs) are as follows:
- 2.4 micrograms (mcg) daily for ages 14 years or older
- 2.6 mcg daily for pregnant women
- 2.8 mcg daily for breastfeeding women
If you’re over the age of 50, you should try to get your RDA by eating foods with B-12 or by taking a supplement containing 25 to 100 mcg of B-12.
Foods with vitamin B-12 include:
- eggs
- cheese
- fish
- shellfish
- liver
- kidney
- red meat
See your doctor if you have bothersome side effects that don’t go away once you stop taking the supplements. Avoid taking supplements if possible, and try to get B-12 from food sources.
If you develop any side effects from taking vitamin B-12, you can stop taking the supplement and the symptoms should subside.
After this, you’ll need to determine either an appropriate dose or how to get the vitamin B-12 you need from food sources. You can discuss this with your doctor.
Article resources
- Cyanocobalamin – cyanocobalamin injection. (2023). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a66eb3c4-3e1d-4d49-b963-4fa2334cc9b6
- Vitamin B12: Fact sheet for health professionals. (2022). https://ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/
Last medically reviewed on June 8, 2023
How we reviewed this article:
Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available.
Current Version
Jun 8, 2023
Written By
Emily Cronkleton
Edited By
John Bassham
Medically Reviewed By
Jared Meacham, Ph. D., RD, PMP, MBA, CSCS
Copy Edited By
Copy Editors
Feb 15, 2023
Written By
Emily Cronkleton
Edited By
Frank Crooks
VIEW ALL HISTORY
Share this article
Medically reviewed by Jared Meacham, Ph.D., RD, PMP, MBA, CSCS — By Emily Cronkleton — Updated on June 8, 2023
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Vitamin B-12 Side Effects
Vitamin B-12 Side Effects
- Health Conditions
- Featured
- Breast Cancer
- IBD
- Migraine
- Multiple Sclerosis (MS)
- Rheumatoid Arthritis
- Type 2 Diabetes
- Articles
- Acid Reflux
- ADHD
- Allergies
- Alzheimer’s & Dementia
- Bipolar Disorder
- Cancer
- Crohn’s Disease
- Chronic Pain
- Cold & Flu
- COPD
- Depression
- Fibromyalgia
- Heart Disease
- High Cholesterol
- HIV
- Hypertension
- IPF
- Osteoarthritis
- Psoriasis
- Skin Disorders and Care
- STDs
- Featured
- Discover
- Wellness Topics
- Nutrition
- Fitness
- Skin Care
- Sexual Health
- Women’s Health
- Mental Well-Being
- Sleep
- Product Reviews
- Vitamins & Supplements
- Sleep
- Mental Health
- Nutrition
- At-Home Testing
- CBD
- Men’s Health
- Original Series
- Fresh Food Fast
- Diagnosis Diaries
- You’re Not Alone
- Present Tense
- Video Series
- Youth in Focus
- Healthy Harvest
- No More Silence
- Future of Health
- Wellness Topics
- Plan
- Health Challenges
- Mindful Eating
- Sugar Savvy
- Move Your Body
- Gut Health
- Mood Foods
- Align Your Spine
- Find Care
- Primary Care
- Mental Health
- OB-GYN
- Dermatologists
- Neurologists
- Cardiologists
- Orthopedists
- Lifestyle Quizzes
- Weight Management
- Am I Depressed? A Quiz for Teens
- Are You a Workaholic?
- How Well Do You Sleep?
- Tools & Resources
- Health News
- Find a Diet
- Find Healthy Snacks
- Drugs A-Z
- Health A-Z
- Health Challenges
- Connect
- Breast Cancer
- Inflammatory Bowel Disease
- Psoriatic Arthritis
- Migraine
- Multiple Sclerosis
- Psoriasis
Medically reviewed by Jared Meacham, Ph. D., RD, PMP, MBA, CSCS — By Emily Cronkleton — Updated on June 8, 2023
Your doctor will give you the right dosage of vitamin B-12 supplement, especially if you will inject it. Taking too much can cause side effects like nausea, headache, dizziness, and in rarely, blood clots or cancer.
Everyone needs vitamin B-12, and most people get enough through their diet. However, it’s important to know what side effects occur when you take too much.
Vitamin B-12 is water-soluble and absorbed in the intestines. After it’s absorbed, it’s used to make DNA and red blood cells. Vitamin B-12 that isn’t being used is stored in the liver. But if you take supplements, you might ingest more than your body needs.
Oral vitamin B-12 is safe to take at recommended doses for healthy people.
Injectable vitamin B-12, which is used to treat significant deficiencies, can cause the following side effects:
- mild diarrhea
- itching
- skin rash
- headache
- dizziness
- nausea
- vomiting
- pulmonary edema and congestive heart failure early in treatment
- vein thrombosis
- sensation of swelling
- polycythemia vera (rare, slow growing blood cancer)
Vitamin B-12 can cause very rare but serious allergic reactions (anaphylaxis). This includes swelling of the face, tongue, and throat, and difficulty swallowing and breathing. If this occurs after you take vitamin B-12, call 911 or your local emergency services immediately.
Some agents are linked to reduced absorption or serum levels of vitamin B-12. You may need vitamin B-12 supplements if you take any of the following:
- colchicine
- metformin
- proton pump inhibitors
- vitamin C
- chloramphenicol
- h3 blockers
- aminosalicylic acid
Folic acid supplements may interfere with vitamin B-12. Be sure to tell your doctor if you take folic acid.
You may need to take vitamin B-12 separately from the above drugs and supplements — say, one in the morning and one at night — so you can get the full dose of vitamin B-12.
Don’t take vitamin B-12 supplements if you have sensitivities or allergies to vitamin B-12, cobalt, and any other ingredients. Vitamin B-12 is safe to take in recommended dosages if you’re pregnant or breastfeeding.
If you notice any adverse effects after you start taking vitamin B-12 supplements, you should discontinue use immediately. Seek medical attention if your symptoms get worse or are severe.
You can consult your doctor to establish an appropriate dose if it’s determined that you don’t get enough B-12 from food sources.
According to the National Institutes of Health, the recommended dietary amounts (RDAs) are as follows:
- 2.4 micrograms (mcg) daily for ages 14 years or older
- 2.6 mcg daily for pregnant women
- 2.8 mcg daily for breastfeeding women
If you’re over the age of 50, you should try to get your RDA by eating foods with B-12 or by taking a supplement containing 25 to 100 mcg of B-12.
Foods with vitamin B-12 include:
- eggs
- cheese
- fish
- shellfish
- liver
- kidney
- red meat
See your doctor if you have bothersome side effects that don’t go away once you stop taking the supplements. Avoid taking supplements if possible, and try to get B-12 from food sources.
If you develop any side effects from taking vitamin B-12, you can stop taking the supplement and the symptoms should subside.
After this, you’ll need to determine either an appropriate dose or how to get the vitamin B-12 you need from food sources. You can discuss this with your doctor.
Article resources
- Cyanocobalamin – cyanocobalamin injection. (2023). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a66eb3c4-3e1d-4d49-b963-4fa2334cc9b6
- Vitamin B12: Fact sheet for health professionals. (2022). https://ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/
Last medically reviewed on June 8, 2023
How we reviewed this article:
Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available.
Current Version
Jun 8, 2023
Written By
Emily Cronkleton
Edited By
John Bassham
Medically Reviewed By
Jared Meacham, Ph. D., RD, PMP, MBA, CSCS
Copy Edited By
Copy Editors
Feb 15, 2023
Written By
Emily Cronkleton
Edited By
Frank Crooks
VIEW ALL HISTORY
Share this article
Medically reviewed by Jared Meacham, Ph.D., RD, PMP, MBA, CSCS — By Emily Cronkleton — Updated on June 8, 2023
Read this next
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Vitamin B12 deficiency can cause various symptoms, and you may wonder whether weight gain is among them. This article reviews whether a vitamin B12…
READ MORE
- What Is a Vitamin B-12 Test?
Medically reviewed by Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT
A vitamin B-12 test measures the amount of B-12 in your blood. Find out what your B-12 results mean and how to optimize your B-12 intake.
READ MORE
- Vitamin B12 (folate deficiency anemia) Signs and Symptoms
By Jillian Kubala, MS, RD
Vitamin B12 is an important water-soluble vitamin that many people are deficient in. Here are nine signs and symptoms of vitamin B12 deficiency.
READ MORE
- Vitamin B12 Dosage: How Much Should You Take per Day?
By Melissa Groves
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READ MORE
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By Rachael Ajmera, MS, RD
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READ MORE
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READ MORE
Cyanocobalamin (Vitamin B12) – instructions for use, doses, side effects, reviews of the drug:
Description of the drug in 1998
Date of approval: 07/31/1998
Content
- Active substance
- ATX
- Pharmacological group
- Nosological classification (ICD-10)
- Composition and form of release
- pharmachologic effect
- pharmachologic effect
- Indications
- Contraindications
- Dosage and administration
- Side effects
- Interaction
- Precautionary measures
- Storage conditions
- Best before date
- Reviews
Active ingredient
Cyanocobalamin* (Cyanocobalamin*)
ATX
B03BA01 Cyanocobalamin
Pharmacological group
Stimulants of hematopoiesis
Vitamins and vitamin-like products
Nosological classification (ICD-10)
ICD-10 code list
Composition and formulation
1 ml solution for injection contains cyanocobalamin (vitamin B 12 ) 200 or 500 mcg; in ampoules of 1 ml, in a cardboard box 10 pcs.
Pharmacological action
Pharmacological action –
hematopoietic , stimulating cell metabolism .
Participates in the transfer of methyl fragments, the formation of choline, methionine, creatine, nucleic acids, the maturation of erythrocytes, promotes the accumulation of compounds containing sulfhydryl groups in erythrocytes.
Participates in the transfer of methyl fragments, the formation of choline, methionine, creatine, nucleic acids, the maturation of erythrocytes, promotes the accumulation of compounds containing sulfhydryl groups in erythrocytes.
Indications
Anemia (Addison-Birmer, alimentary macrocytic, iron deficiency,
posthemorrhagic, aplastic, caused by toxic substances and drugs), cirrhosis of the liver,
hepatitis, myelosis, polyneuritis, sciatica, trigeminal neuralgia, amyotrophic lateral sclerosis, children
cerebral palsy, multiple sclerosis, Down’s disease, skin diseases, peripheral nerve injuries.
Contraindications
Thromboembolism, angina.
Dosage and administration
Information for healthcare professionals only.
Are you a healthcare professional?
S/C, IM, IV and intralumbar.
Addison-Birmer anemia – 100-200 mcg every other day; with Addison-Birmer anemia with symptoms of funicular myelosis and with macrocytic anemia with disorders of the nervous system – 500 mcg or more per injection (daily for the first week, and then with intervals between injections of up to 5-7 days). Simultaneously appoint folic acid. In the period of remission, in the absence of funicular myelosis phenomena, 100 mcg is administered for maintenance therapy 2 times a month, and in the presence of neurological phenomena, 200-400 mcg 2-4 times a month.
For iron deficiency and posthemorrhagic anemia – 30-100 mcg 2-3 times a week; with aplastic anemia (especially in children) – 100 mcg until the onset of clinical and hematological improvement; with alimentary anemia in children at an early age and in premature babies – 30 mcg / day for 15 days.
In diseases of the central nervous system and neurological diseases with pain syndrome, it is administered in increasing doses from 200 to 500 mcg per injection, and when the condition improves, 100 mcg/day; course – up to 2 weeks.
In traumatic lesions of the peripheral nerves – 200-400 mcg every other day for 40-45 days.
For hepatitis and liver cirrhosis, 30–60 mcg per day or 100 mcg every other day for 25–40 days.
With dystrophies in young children, Down’s disease and cerebral palsy – 15-30 mcg every other day.
In case of funicular myelosis, amyotrophic lateral sclerosis, multiple sclerosis, sometimes 15-30 mcg is injected into the spinal canal (gradually increasing the dose to 200-250 mcg).
Side effects
Excitation, pain in the heart, tachycardia, allergic reactions.
Interactions
Information for healthcare professionals only.
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Incompatible (in one syringe) with thiamine bromide, riboflavin.
Precautions
In angina pectoris, use with caution and in lower doses.
Storage conditions
In a place protected from light.
Keep out of reach of children.
Expiry date
2 years.
Do not use after the expiry date which is stated on the packaging.
Update date: 04/30/2020
Vitamin B12 – instructions for use, doses, side effects, reviews of the drug: instant tablets, 5000 mcg
0.004 ‰
Analogs
Description selection
Lec. form | Dosage |
---|---|
instant tablets | 5000 mcg |
injection | 0. 2 mg/ml |
instant tablets
5000 mcg
injection
0.2 mg/ml
All forms of release, dosages, registration certificates, drug manufacturers, drug characteristics
Product description Vitamin B12 (solution for injection, 0.2 mg/ml) based on the official instructions, approved by the manufacturer in 1998
Date approved: 07/31/1998
Contents
- Active substance
- ATX
- Pharmacological group
- Composition and form of release
- Dosage and administration
- Storage conditions
- Best before date
- Reviews
Active ingredient
Cyanocobalamin* (Cyanocobalamin*)
ATX
B03BA01 Cyanocobalamin
Pharmacological group
Stimulants of hematopoiesis
Vitamins and vitamin-like products
Composition and form of release
1 ampoule with 1 ml solution for injection contains cyanocobalamin 200 or 500 mcg; in a box of 10 pcs. , complete with ampoule knife.
Dosage and administration
Information for healthcare professionals only.
Are you a healthcare professional?
S/C, IM, IV and intralumbar. For Addison-Birmer anemia (in combination with folic acid)
– 100-200 mcg once a day, for 2 days; with Addison-Birmer anemia with symptoms
funicular myelosis and macrocytic anemia with disorders of the nervous system – 500 mcg and
more per injection (in the first week daily, and then at intervals between injections up to 5-7 days). During
remissions – 100 mcg 2 times a month (maintenance therapy), in the presence of neurological phenomena
(funicular myelosis) – 200-400 mcg 2-4 times a month. With iron deficiency and
posthemorrhagic anemia – 30-100 mcg 2-3 times a week; with aplastic anemia
(especially in children) – 100 mcg until the onset of clinical and hematological improvement; with alimentary
anemia in children at an early age and in premature babies – 30 mcg / day for 15 days.