What are the potential side effects of vitamin B-12 supplements. How much vitamin B-12 do you need daily. Can vitamin B-12 interact with other medications. What foods are good natural sources of vitamin B-12.

The Importance of Vitamin B-12 and Its Functions

Vitamin B-12 plays a crucial role in our body’s proper functioning. This essential nutrient is involved in several vital processes:

• DNA synthesis
• Red blood cell production
• Nervous system maintenance
• Energy metabolism

While most people obtain sufficient vitamin B-12 through their diet, some individuals may require supplementation. Understanding the potential side effects of vitamin B-12 supplements is essential for those considering or currently taking them.

Common Side Effects of Vitamin B-12 Supplements

When taken as directed, oral vitamin B-12 supplements are generally safe for healthy individuals. However, some people may experience mild side effects, especially when taking higher doses or injectable forms of the vitamin.

Oral Supplement Side Effects

Common side effects of oral vitamin B-12 supplements may include:

• Headache
• Nausea
• Dizziness
• Mild diarrhea

Injectable Vitamin B-12 Side Effects

Injectable vitamin B-12, often used to treat severe deficiencies, may cause additional side effects such as:

• Itching
• Skin rash
• Vomiting
• Sensation of swelling
• Pulmonary edema (in rare cases)
• Congestive heart failure (early in treatment)
• Vein thrombosis

Are there any serious side effects associated with vitamin B-12 supplementation? While rare, some individuals may experience severe allergic reactions (anaphylaxis) to vitamin B-12. Symptoms of anaphylaxis include swelling of the face, tongue, and throat, as well as difficulty swallowing and breathing. If you experience these symptoms after taking vitamin B-12, seek emergency medical attention immediately.

Interactions Between Vitamin B-12 and Other Medications

Certain medications can interfere with the absorption or effectiveness of vitamin B-12. It’s crucial to inform your healthcare provider about all medications and supplements you’re taking to avoid potential interactions.

Medications That May Affect Vitamin B-12 Absorption

The following medications may reduce the absorption or serum levels of vitamin B-12:

• Colchicine
• Metformin
• Proton pump inhibitors
• Vitamin C
• Chloramphenicol
• H3 blockers
• Aminosalicylic acid

If you’re taking any of these medications, your healthcare provider may recommend vitamin B-12 supplementation or adjusting the timing of your doses to ensure optimal absorption.

Interaction with Folic Acid

Folic acid supplements may interfere with vitamin B-12 absorption. If you’re taking both supplements, consult your doctor about the appropriate timing and dosage to avoid potential interactions.

Recommended Dietary Allowances (RDAs) for Vitamin B-12

The National Institutes of Health has established recommended dietary allowances (RDAs) for vitamin B-12 based on age and specific conditions:

• Ages 14 years and older: 2.4 micrograms (mcg) daily
• Pregnant women: 2.6 mcg daily
• Breastfeeding women: 2.8 mcg daily

For individuals over 50 years of age, it’s recommended to obtain the RDA through fortified foods or supplements containing 25 to 100 mcg of vitamin B-12, as absorption may decrease with age.

Natural Sources of Vitamin B-12

While supplements can be beneficial for some individuals, obtaining nutrients from whole foods is generally preferred. Vitamin B-12 is naturally found in various animal-based products:

• Eggs
• Cheese
• Fish
• Shellfish
• Liver
• Kidney
• Red meat

For vegetarians and vegans, fortified plant-based milk, cereals, and nutritional yeast can be good sources of vitamin B-12.

Managing Side Effects and Proper Supplementation

If you experience side effects from vitamin B-12 supplements, it’s essential to address them promptly. Here are some steps to manage potential issues:

1. Discontinue use if adverse effects occur
2. Consult your healthcare provider about adjusting the dosage
3. Consider alternative forms of supplementation (e.g., sublingual tablets or nasal sprays)
4. Explore natural food sources of vitamin B-12

How can you determine the right vitamin B-12 dosage for your needs? The best approach is to consult with a healthcare professional. They can assess your individual needs, consider any underlying health conditions, and recommend an appropriate dosage or supplementation method.

Special Considerations for Vitamin B-12 Supplementation

While vitamin B-12 is generally safe for most people, there are some special considerations to keep in mind:

Pregnancy and Breastfeeding

Vitamin B-12 is considered safe during pregnancy and breastfeeding when taken in recommended dosages. However, it’s essential to consult with your healthcare provider before starting any new supplement regimen during these periods.

Allergies and Sensitivities

Individuals with known sensitivities or allergies to vitamin B-12, cobalt, or other ingredients in B-12 supplements should avoid taking them. Always check the ingredient list and consult with a healthcare professional if you have concerns about potential allergic reactions.

Underlying Health Conditions

Certain health conditions may affect vitamin B-12 absorption or metabolism. These include:

• Pernicious anemia
• Atrophic gastritis
• Crohn’s disease
• Celiac disease
• Surgical removal of parts of the stomach or small intestine

If you have any of these conditions, your healthcare provider may recommend specific forms or doses of vitamin B-12 supplementation.

Monitoring Vitamin B-12 Levels and Adjusting Supplementation

Regular monitoring of vitamin B-12 levels can help ensure that you’re maintaining optimal levels without overdosing. Your healthcare provider may recommend periodic blood tests to assess your vitamin B-12 status.

Signs of Vitamin B-12 Deficiency

Recognizing the signs of vitamin B-12 deficiency can help you determine if supplementation is necessary. Common symptoms include:

• Fatigue
• Weakness
• Constipation
• Loss of appetite
• Weight loss
• Numbness and tingling in the hands and feet
• Difficulty maintaining balance
• Depression
• Confusion
• Poor memory
• Soreness of the mouth or tongue

If you experience any of these symptoms, consult your healthcare provider for proper evaluation and treatment.

Adjusting Supplementation Based on Test Results

Based on your blood test results, your healthcare provider may recommend adjusting your vitamin B-12 supplementation. This could involve:

• Increasing or decreasing the dosage
• Changing the form of supplementation (e.g., from oral to injectable)
• Addressing underlying causes of deficiency
• Recommending dietary changes to increase natural vitamin B-12 intake

How often should you have your vitamin B-12 levels checked? The frequency of testing depends on individual factors such as age, health status, and risk of deficiency. Your healthcare provider can recommend an appropriate testing schedule based on your specific needs.

Alternative Forms of Vitamin B-12 Supplementation

While oral tablets are the most common form of vitamin B-12 supplementation, there are alternative options available for those who may have difficulty with absorption or prefer different methods:

Sublingual Tablets

Sublingual tablets are designed to dissolve under the tongue, potentially improving absorption by bypassing the digestive system. These may be beneficial for individuals with gastrointestinal issues that affect nutrient absorption.

Nasal Sprays

Vitamin B-12 nasal sprays offer another alternative for those who have difficulty swallowing pills or have absorption issues. The vitamin is absorbed directly through the nasal mucosa, potentially improving bioavailability.

Transdermal Patches

Vitamin B-12 patches deliver the nutrient through the skin. While less common, they may be an option for individuals who prefer a steady, continuous delivery of the vitamin.

Intramuscular Injections

For severe deficiencies or conditions that significantly impair absorption, intramuscular injections of vitamin B-12 may be prescribed. These are typically administered by a healthcare professional and can quickly raise B-12 levels in the body.

Which form of vitamin B-12 supplementation is most effective? The effectiveness of different forms can vary depending on individual factors such as age, health status, and the presence of underlying conditions affecting absorption. Consulting with a healthcare provider can help determine the most appropriate form of supplementation for your specific needs.

Long-term Considerations for Vitamin B-12 Supplementation

While vitamin B-12 supplementation can be beneficial, it’s important to consider the long-term implications of continued use:

Potential for Oversupplementation

Although vitamin B-12 is water-soluble and excess amounts are generally excreted in urine, long-term oversupplementation may lead to:

• Acne or rosacea-like symptoms
• Excess blood volume (polycythemia vera)
• Increased risk of lung cancer in men (in combination with high folate intake)

Regular Assessment of Need

As your nutritional needs and health status may change over time, it’s important to regularly assess whether continued supplementation is necessary. Factors to consider include:

• Changes in diet
• Improvements in underlying health conditions
• Age-related changes in absorption
• Development of new health conditions

Lifestyle Factors Affecting Vitamin B-12 Status

Certain lifestyle factors can impact your vitamin B-12 status and the need for supplementation:

• Alcohol consumption: Heavy alcohol use can interfere with B-12 absorption and metabolism
• Smoking: Nicotine can reduce serum B-12 levels
• Stress: Chronic stress may increase the body’s demand for B vitamins
• Exercise: Intense physical activity may increase the need for B-12 and other nutrients

How can you ensure long-term safety and effectiveness of vitamin B-12 supplementation? Regular check-ups with your healthcare provider, periodic blood tests to assess B-12 levels, and open communication about any changes in your health or lifestyle are key to maintaining optimal vitamin B-12 status while minimizing the risk of side effects or oversupplementation.

The Role of Vitamin B-12 in Overall Health and Wellness

Understanding the broader impact of vitamin B-12 on health can help contextualize the importance of maintaining optimal levels:

Neurological Health

Vitamin B-12 plays a crucial role in maintaining the health of the nervous system. Adequate levels are essential for:

• Myelin production (the protective coating around nerves)
• Neurotransmitter synthesis
• Cognitive function and memory
• Mood regulation

Cardiovascular Health

Vitamin B-12, along with other B vitamins, is involved in regulating homocysteine levels in the blood. Maintaining healthy homocysteine levels is associated with:

• Reduced risk of heart disease
• Lower risk of stroke
• Improved overall cardiovascular health

Bone Health

Emerging research suggests that vitamin B-12 may play a role in maintaining bone health, particularly in older adults. Adequate B-12 levels are associated with:

• Improved bone mineral density
• Reduced risk of osteoporosis
• Better overall bone metabolism

Energy Production and Metabolism

Vitamin B-12 is essential for energy production at the cellular level. Maintaining optimal B-12 levels can contribute to:

• Improved energy levels and reduced fatigue
• Enhanced metabolic function
• Better overall physical performance

How does vitamin B-12 contribute to overall wellness beyond its basic functions? By supporting neurological health, cardiovascular function, bone health, and energy production, vitamin B-12 plays a multifaceted role in maintaining overall health and well-being. This underscores the importance of maintaining adequate B-12 levels through diet or supplementation when necessary.

In conclusion, while vitamin B-12 supplementation can be beneficial and even necessary for some individuals, it’s important to approach it with an understanding of potential side effects, proper dosage, and individual needs. Regular consultation with healthcare providers, monitoring of B-12 levels, and awareness of personal health status are key to maximizing the benefits of vitamin B-12 while minimizing potential risks. By taking a holistic approach to vitamin B-12 intake and overall nutrition, individuals can support their health and well-being effectively and safely.

Vitamin B-12 Side Effects

Vitamin B-12 Side Effects

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Medically reviewed by Jared Meacham, Ph. D., RD, PMP, MBA, CSCS — By Emily Cronkleton — Updated on June 8, 2023

Your doctor will give you the right dosage of vitamin B-12 supplement, especially if you will inject it. Taking too much can cause side effects like nausea, headache, dizziness, and in rarely, blood clots or cancer.

Everyone needs vitamin B-12, and most people get enough through their diet. However, it’s important to know what side effects occur when you take too much.

Vitamin B-12 is water-soluble and absorbed in the intestines. After it’s absorbed, it’s used to make DNA and red blood cells. Vitamin B-12 that isn’t being used is stored in the liver. But if you take supplements, you might ingest more than your body needs.

Oral vitamin B-12 is safe to take at recommended doses for healthy people.

Injectable vitamin B-12, which is used to treat significant deficiencies, can cause the following side effects:

• mild diarrhea
• itching
• skin rash
• headache
• dizziness
• nausea
• vomiting
• pulmonary edema and congestive heart failure early in treatment
• vein thrombosis
• sensation of swelling
• polycythemia vera (rare, slow growing blood cancer)

Vitamin B-12 can cause very rare but serious allergic reactions (anaphylaxis). This includes swelling of the face, tongue, and throat, and difficulty swallowing and breathing. If this occurs after you take vitamin B-12, call 911 or your local emergency services immediately.

Some agents are linked to reduced absorption or serum levels of vitamin B-12. You may need vitamin B-12 supplements if you take any of the following:

• colchicine
• metformin
• proton pump inhibitors
• vitamin C
• chloramphenicol
• h3 blockers
• aminosalicylic acid

Folic acid supplements may interfere with vitamin B-12. Be sure to tell your doctor if you take folic acid.

You may need to take vitamin B-12 separately from the above drugs and supplements — say, one in the morning and one at night — so you can get the full dose of vitamin B-12.

Don’t take vitamin B-12 supplements if you have sensitivities or allergies to vitamin B-12, cobalt, and any other ingredients. Vitamin B-12 is safe to take in recommended dosages if you’re pregnant or breastfeeding.

If you notice any adverse effects after you start taking vitamin B-12 supplements, you should discontinue use immediately. Seek medical attention if your symptoms get worse or are severe.

You can consult your doctor to establish an appropriate dose if it’s determined that you don’t get enough B-12 from food sources.

According to the National Institutes of Health, the recommended dietary amounts (RDAs) are as follows:

• 2.4 micrograms (mcg) daily for ages 14 years or older
• 2.6 mcg daily for pregnant women
• 2.8 mcg daily for breastfeeding women

If you’re over the age of 50, you should try to get your RDA by eating foods with B-12 or by taking a supplement containing 25 to 100 mcg of B-12.

Foods with vitamin B-12 include:

• eggs
• cheese
• fish
• shellfish
• liver
• kidney
• red meat

See your doctor if you have bothersome side effects that don’t go away once you stop taking the supplements. Avoid taking supplements if possible, and try to get B-12 from food sources.

If you develop any side effects from taking vitamin B-12, you can stop taking the supplement and the symptoms should subside.

After this, you’ll need to determine either an appropriate dose or how to get the vitamin B-12 you need from food sources. You can discuss this with your doctor.

Article resources

• Cyanocobalamin – cyanocobalamin injection. (2023). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a66eb3c4-3e1d-4d49-b963-4fa2334cc9b6
• Vitamin B12: Fact sheet for health professionals. (2022). https://ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/

Last medically reviewed on June 8, 2023

How we reviewed this article:

Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available.

Current Version

Jun 8, 2023

Written By

Emily Cronkleton

Edited By

John Bassham

Medically Reviewed By

Jared Meacham, Ph. D., RD, PMP, MBA, CSCS

Copy Edited By

Copy Editors

Feb 15, 2023

Written By

Emily Cronkleton

Edited By

Frank Crooks

VIEW ALL HISTORY

Share this article

Medically reviewed by Jared Meacham, Ph.D., RD, PMP, MBA, CSCS — By Emily Cronkleton — Updated on June 8, 2023

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Vitamin B-12 Side Effects

Vitamin B-12 Side Effects

• Health Conditions
  • Featured
    • Breast Cancer
    • IBD
    • Migraine
    • Multiple Sclerosis (MS)
    • Rheumatoid Arthritis
    • Type 2 Diabetes
  • Articles
    • Acid Reflux
    • ADHD
    • Allergies
    • Alzheimer’s & Dementia
    • Bipolar Disorder
    • Cancer
    • Crohn’s Disease
    • Chronic Pain
    • Cold & Flu
    • COPD
    • Depression
    • Fibromyalgia
    • Heart Disease
    • High Cholesterol
    • HIV
    • Hypertension
    • IPF
    • Osteoarthritis
    • Psoriasis
    • Skin Disorders and Care
    • STDs
• Discover
  • Wellness Topics
    • Nutrition
    • Fitness
    • Skin Care
    • Sexual Health
    • Women’s Health
    • Mental Well-Being
    • Sleep
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    • Vitamins & Supplements
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    • Mental Health
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    • At-Home Testing
    • CBD
    • Men’s Health
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    • Diagnosis Diaries
    • You’re Not Alone
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  • Video Series
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    • Healthy Harvest
    • No More Silence
    • Future of Health
• Plan
  • Health Challenges
    • Mindful Eating
    • Sugar Savvy
    • Move Your Body
    • Gut Health
    • Mood Foods
    • Align Your Spine
  • Find Care
    • Primary Care
    • Mental Health
    • OB-GYN
    • Dermatologists
    • Neurologists
    • Cardiologists
    • Orthopedists
  • Lifestyle Quizzes
    • Weight Management
    • Am I Depressed? A Quiz for Teens
    • Are You a Workaholic?
    • How Well Do You Sleep?
  • Tools & Resources
    • Health News
    • Find a Diet
    • Find Healthy Snacks
    • Drugs A-Z
    • Health A-Z
• Connect
  • • Breast Cancer
    • Inflammatory Bowel Disease
    • Psoriatic Arthritis
    • Migraine
    • Multiple Sclerosis
    • Psoriasis

Medically reviewed by Jared Meacham, Ph. D., RD, PMP, MBA, CSCS — By Emily Cronkleton — Updated on June 8, 2023

Your doctor will give you the right dosage of vitamin B-12 supplement, especially if you will inject it. Taking too much can cause side effects like nausea, headache, dizziness, and in rarely, blood clots or cancer.

Everyone needs vitamin B-12, and most people get enough through their diet. However, it’s important to know what side effects occur when you take too much.

Vitamin B-12 is water-soluble and absorbed in the intestines. After it’s absorbed, it’s used to make DNA and red blood cells. Vitamin B-12 that isn’t being used is stored in the liver. But if you take supplements, you might ingest more than your body needs.

Oral vitamin B-12 is safe to take at recommended doses for healthy people.

Injectable vitamin B-12, which is used to treat significant deficiencies, can cause the following side effects:

• mild diarrhea
• itching
• skin rash
• headache
• dizziness
• nausea
• vomiting
• pulmonary edema and congestive heart failure early in treatment
• vein thrombosis
• sensation of swelling
• polycythemia vera (rare, slow growing blood cancer)

Vitamin B-12 can cause very rare but serious allergic reactions (anaphylaxis). This includes swelling of the face, tongue, and throat, and difficulty swallowing and breathing. If this occurs after you take vitamin B-12, call 911 or your local emergency services immediately.

Some agents are linked to reduced absorption or serum levels of vitamin B-12. You may need vitamin B-12 supplements if you take any of the following:

• colchicine
• metformin
• proton pump inhibitors
• vitamin C
• chloramphenicol
• h3 blockers
• aminosalicylic acid

Folic acid supplements may interfere with vitamin B-12. Be sure to tell your doctor if you take folic acid.

You may need to take vitamin B-12 separately from the above drugs and supplements — say, one in the morning and one at night — so you can get the full dose of vitamin B-12.

Don’t take vitamin B-12 supplements if you have sensitivities or allergies to vitamin B-12, cobalt, and any other ingredients. Vitamin B-12 is safe to take in recommended dosages if you’re pregnant or breastfeeding.

If you notice any adverse effects after you start taking vitamin B-12 supplements, you should discontinue use immediately. Seek medical attention if your symptoms get worse or are severe.

You can consult your doctor to establish an appropriate dose if it’s determined that you don’t get enough B-12 from food sources.

According to the National Institutes of Health, the recommended dietary amounts (RDAs) are as follows:

• 2.4 micrograms (mcg) daily for ages 14 years or older
• 2.6 mcg daily for pregnant women
• 2.8 mcg daily for breastfeeding women

If you’re over the age of 50, you should try to get your RDA by eating foods with B-12 or by taking a supplement containing 25 to 100 mcg of B-12.

Foods with vitamin B-12 include:

• eggs
• cheese
• fish
• shellfish
• liver
• kidney
• red meat

See your doctor if you have bothersome side effects that don’t go away once you stop taking the supplements. Avoid taking supplements if possible, and try to get B-12 from food sources.

If you develop any side effects from taking vitamin B-12, you can stop taking the supplement and the symptoms should subside.

After this, you’ll need to determine either an appropriate dose or how to get the vitamin B-12 you need from food sources. You can discuss this with your doctor.

Article resources

• Cyanocobalamin – cyanocobalamin injection. (2023). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a66eb3c4-3e1d-4d49-b963-4fa2334cc9b6
• Vitamin B12: Fact sheet for health professionals. (2022). https://ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/

Last medically reviewed on June 8, 2023

How we reviewed this article:

Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available.

Current Version

Jun 8, 2023

Written By

Emily Cronkleton

Edited By

John Bassham

Medically Reviewed By

Jared Meacham, Ph. D., RD, PMP, MBA, CSCS

Copy Edited By

Copy Editors

Feb 15, 2023

Written By

Emily Cronkleton

Edited By

Frank Crooks

VIEW ALL HISTORY

Share this article

Medically reviewed by Jared Meacham, Ph.D., RD, PMP, MBA, CSCS — By Emily Cronkleton — Updated on June 8, 2023

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• What Is a Vitamin B-12 Test?

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• Vitamin B12 (folate deficiency anemia) Signs and Symptoms

  By Jillian Kubala, MS, RD

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  READ MORE

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  By Ansley Hill, RD, LD

  Pueraria mirifica — or Kwao Krua — has long been used as a rejuvenation therapy in traditional Thai medicine practices. Here are 7 emerging health…

  READ MORE

Cyanocobalamin (Vitamin B12) – instructions for use, doses, side effects, reviews of the drug:

Description of the drug in 1998

Date of approval: 07/31/1998

Content

• Active substance
• ATX
• Pharmacological group
• Nosological classification (ICD-10)
• Composition and form of release
• pharmachologic effect
• pharmachologic effect
• Indications
• Contraindications
• Dosage and administration
• Side effects
• Interaction
• Precautionary measures
• Storage conditions
• Best before date
• Reviews

Active ingredient

Cyanocobalamin* (Cyanocobalamin*)

ATX

B03BA01 Cyanocobalamin

Pharmacological group

Stimulants of hematopoiesis

Vitamins and vitamin-like products

Nosological classification (ICD-10)

ICD-10 code list

Composition and formulation

1 ml solution for injection contains cyanocobalamin (vitamin B ₁₂ ) 200 or 500 mcg; in ampoules of 1 ml, in a cardboard box 10 pcs.

Pharmacological action

Pharmacological action –

hematopoietic , stimulating cell metabolism .

Participates in the transfer of methyl fragments, the formation of choline, methionine, creatine, nucleic acids, the maturation of erythrocytes, promotes the accumulation of compounds containing sulfhydryl groups in erythrocytes.

Participates in the transfer of methyl fragments, the formation of choline, methionine, creatine, nucleic acids, the maturation of erythrocytes, promotes the accumulation of compounds containing sulfhydryl groups in erythrocytes.

Indications

Anemia (Addison-Birmer, alimentary macrocytic, iron deficiency,
posthemorrhagic, aplastic, caused by toxic substances and drugs), cirrhosis of the liver,
hepatitis, myelosis, polyneuritis, sciatica, trigeminal neuralgia, amyotrophic lateral sclerosis, children
cerebral palsy, multiple sclerosis, Down’s disease, skin diseases, peripheral nerve injuries.

Contraindications

Thromboembolism, angina.

Dosage and administration

Information for healthcare professionals only.
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S/C, IM, IV and intralumbar.

Addison-Birmer anemia – 100-200 mcg every other day; with Addison-Birmer anemia with symptoms of funicular myelosis and with macrocytic anemia with disorders of the nervous system – 500 mcg or more per injection (daily for the first week, and then with intervals between injections of up to 5-7 days). Simultaneously appoint folic acid. In the period of remission, in the absence of funicular myelosis phenomena, 100 mcg is administered for maintenance therapy 2 times a month, and in the presence of neurological phenomena, 200-400 mcg 2-4 times a month.

For iron deficiency and posthemorrhagic anemia – 30-100 mcg 2-3 times a week; with aplastic anemia (especially in children) – 100 mcg until the onset of clinical and hematological improvement; with alimentary anemia in children at an early age and in premature babies – 30 mcg / day for 15 days.

In diseases of the central nervous system and neurological diseases with pain syndrome, it is administered in increasing doses from 200 to 500 mcg per injection, and when the condition improves, 100 mcg/day; course – up to 2 weeks.

In traumatic lesions of the peripheral nerves – 200-400 mcg every other day for 40-45 days.

For hepatitis and liver cirrhosis, 30–60 mcg per day or 100 mcg every other day for 25–40 days.

With dystrophies in young children, Down’s disease and cerebral palsy – 15-30 mcg every other day.

In case of funicular myelosis, amyotrophic lateral sclerosis, multiple sclerosis, sometimes 15-30 mcg is injected into the spinal canal (gradually increasing the dose to 200-250 mcg).

Side effects

Excitation, pain in the heart, tachycardia, allergic reactions.

Interactions

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Incompatible (in one syringe) with thiamine bromide, riboflavin.

Precautions

In angina pectoris, use with caution and in lower doses.

Storage conditions

In a place protected from light.

Keep out of reach of children.

Expiry date

2 years.

Do not use after the expiry date which is stated on the packaging.

Update date: 04/30/2020

Vitamin B12 – instructions for use, doses, side effects, reviews of the drug: instant tablets, 5000 mcg

0.004 ‰

Analogs

Description selection

instant tablets

5000 mcg

injection

0.2 mg/ml

All forms of release, dosages, registration certificates, drug manufacturers, drug characteristics

Product description Vitamin B12 (solution for injection, 0.2 mg/ml) based on the official instructions, approved by the manufacturer in 1998

Date approved: 07/31/1998

Contents

• Active substance
• ATX
• Pharmacological group
• Composition and form of release
• Dosage and administration
• Storage conditions
• Best before date
• Reviews

Active ingredient

Cyanocobalamin* (Cyanocobalamin*)

ATX

B03BA01 Cyanocobalamin

Pharmacological group

Stimulants of hematopoiesis

Vitamins and vitamin-like products

Composition and form of release

1 ampoule with 1 ml solution for injection contains cyanocobalamin 200 or 500 mcg; in a box of 10 pcs. , complete with ampoule knife.

Dosage and administration

Information for healthcare professionals only.
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S/C, IM, IV and intralumbar. For Addison-Birmer anemia (in combination with folic acid)
– 100-200 mcg once a day, for 2 days; with Addison-Birmer anemia with symptoms
funicular myelosis and macrocytic anemia with disorders of the nervous system – 500 mcg and
more per injection (in the first week daily, and then at intervals between injections up to 5-7 days). During
remissions – 100 mcg 2 times a month (maintenance therapy), in the presence of neurological phenomena
(funicular myelosis) – 200-400 mcg 2-4 times a month. With iron deficiency and
posthemorrhagic anemia – 30-100 mcg 2-3 times a week; with aplastic anemia
(especially in children) – 100 mcg until the onset of clinical and hematological improvement; with alimentary
anemia in children at an early age and in premature babies – 30 mcg / day for 15 days.