Side effects of calcium and vitamin d. Calcium and Vitamin D Combination: Benefits, Side Effects, and Usage Guide

11.07.202310.06.2023 by alexxlab

What are the key benefits of calcium and vitamin D combination supplements. How do these supplements promote bone health and prevent osteoporosis. What are the potential side effects and precautions to consider when taking calcium and vitamin D supplements.

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Understanding Calcium and Vitamin D Combination Supplements

Calcium and vitamin D combination supplements, such as Calcium 500+D, are widely used to promote bone health, treat calcium deficiencies, and protect against osteoporosis. These supplements combine two essential nutrients that work synergistically to support skeletal strength and overall well-being.

Calcium, a natural mineral, plays a crucial role in bone formation and maintenance. Vitamin D, on the other hand, enhances the body’s ability to absorb calcium effectively. Together, these nutrients form a powerful duo that helps maintain optimal bone density and strength throughout life.

Key Components of Calcium and Vitamin D Supplements

Calcium: A vital mineral for bone health and various bodily functions
Vitamin D: Essential for calcium absorption and bone mineralization
Additional ingredients: May include other minerals or substances to enhance absorption

The Importance of Calcium and Vitamin D for Bone Health

Maintaining strong and healthy bones is crucial for overall health and mobility. Calcium and vitamin D play pivotal roles in this process. But how exactly do these nutrients contribute to bone health?

Calcium is the primary building block of bones and teeth. It provides structural support and strength to the skeletal system. Without adequate calcium, bones can become weak and brittle, increasing the risk of fractures and osteoporosis.

Vitamin D acts as a facilitator in this process. It enhances the body’s ability to absorb calcium from the digestive tract and helps deposit calcium into the bones. Without sufficient vitamin D, even a calcium-rich diet may not provide optimal bone health benefits.

Benefits of Calcium and Vitamin D for Bone Health

Increased bone density and strength
Reduced risk of osteoporosis and fractures
Improved muscle function and balance
Support for proper nerve signaling
Maintenance of healthy teeth

Medical Uses of Calcium and Vitamin D Combination Supplements

Calcium and vitamin D combination supplements are prescribed or recommended for various medical purposes. These supplements can address specific health concerns and support overall well-being. But what are the primary medical uses of these supplements?

Common Medical Uses

Treatment of osteoporosis
Prevention of calcium deficiency
Management of hyperparathyroidism
Support during pregnancy and breastfeeding
Treatment of rickets in children

For individuals with osteoporosis, these supplements can help slow bone loss and reduce the risk of fractures. In cases of calcium deficiency, they can quickly replenish calcium levels and prevent associated symptoms. Pregnant and breastfeeding women often require additional calcium and vitamin D to support fetal development and maintain their own bone health.

Potential Side Effects and Precautions

While calcium and vitamin D supplements are generally safe for most people, they can cause side effects in some individuals. It’s important to be aware of potential adverse reactions and take necessary precautions. What are the most common side effects associated with these supplements?

Common Side Effects

Constipation
Nausea
Stomach discomfort
Headache
Dry mouth

In rare cases, more serious side effects may occur, such as kidney stones or hypercalcemia (excessive calcium in the blood). It’s crucial to follow recommended dosages and consult a healthcare professional before starting any new supplement regimen.

Precautions and Contraindications

Certain individuals should exercise caution or avoid calcium and vitamin D supplements altogether. These include people with:

Kidney disease or a history of kidney stones
High blood calcium levels
Certain heart conditions
Sarcoidosis or other granulomatous diseases

Always consult with a healthcare provider before starting these supplements, especially if you have any pre-existing medical conditions or are taking other medications.

Proper Dosage and Administration

Determining the right dosage of calcium and vitamin D supplements is crucial for maximizing benefits while minimizing potential risks. How much should you take, and what factors influence the appropriate dosage?

The recommended daily intake of calcium varies depending on age, sex, and individual health factors. For most adults, the recommended dietary allowance (RDA) ranges from 1000 to 1200 mg per day. Vitamin D requirements typically range from 600 to 800 IU daily for adults.

Factors Affecting Dosage

Age and sex
Pregnancy or breastfeeding status
Existing medical conditions
Dietary intake of calcium and vitamin D
Sun exposure (for vitamin D)

It’s important to note that more is not always better when it comes to these supplements. Excessive intake can lead to adverse effects. Always follow the dosage instructions provided by your healthcare provider or on the product label.

Interactions with Other Medications and Supplements

Calcium and vitamin D supplements can interact with various medications and other supplements, potentially affecting their efficacy or increasing the risk of side effects. What are some common interactions to be aware of?

Medications That May Interact with Calcium and Vitamin D

Antibiotics (e.g., tetracyclines, fluoroquinolones)
Bisphosphonates (used to treat osteoporosis)
Thiazide diuretics
Corticosteroids
Anticonvulsants

To avoid potential interactions, it’s crucial to inform your healthcare provider about all medications and supplements you’re taking before starting calcium and vitamin D supplementation. They can advise on proper timing and dosage to minimize interaction risks.

Dietary Sources of Calcium and Vitamin D

While supplements can be beneficial, obtaining calcium and vitamin D through dietary sources is often preferable. What are some natural food sources rich in these nutrients?

Calcium-Rich Foods

Dairy products (milk, yogurt, cheese)
Leafy green vegetables (kale, collard greens, spinach)
Fortified plant-based milk alternatives
Sardines and canned salmon (with bones)
Tofu (made with calcium sulfate)

Vitamin D Sources

Fatty fish (salmon, mackerel, tuna)
Egg yolks
Fortified foods (cereals, orange juice)
Mushrooms exposed to UV light
Sunlight exposure (promotes vitamin D synthesis in the skin)

Incorporating these foods into your diet can help ensure adequate intake of calcium and vitamin D. However, for individuals with dietary restrictions or increased needs, supplements may still be necessary to meet recommended levels.

Special Considerations for Different Age Groups

The need for calcium and vitamin D varies throughout life, with certain age groups requiring special attention. How do requirements change across different life stages?

Children and Adolescents

Growing children and teenagers have increased calcium needs to support rapid bone development. Adequate vitamin D is crucial during this period to ensure proper calcium absorption and bone mineralization. The recommended daily intake for calcium ranges from 700 to 1300 mg, depending on age, while vitamin D requirements are typically 600 IU per day.

Adults

For most adults, the recommended daily intake of calcium is 1000 mg, increasing to 1200 mg for women over 50 and men over 70. Vitamin D requirements remain at 600 IU per day for adults up to age 70, after which they increase to 800 IU daily.

Pregnant and Breastfeeding Women

During pregnancy and lactation, calcium and vitamin D needs increase to support fetal development and maintain maternal bone health. Pregnant and breastfeeding women typically require 1000 mg of calcium and 600 IU of vitamin D daily.

Older Adults

As we age, the risk of osteoporosis increases, particularly in postmenopausal women. Older adults may require higher doses of calcium and vitamin D to maintain bone density and reduce fracture risk. Many healthcare providers recommend 1200 mg of calcium and 800-1000 IU of vitamin D daily for individuals over 70.

It’s important to note that these are general guidelines, and individual needs may vary. Consulting with a healthcare provider can help determine the most appropriate supplementation strategy based on age, health status, and other factors.

Choosing the Right Calcium and Vitamin D Supplement

With numerous calcium and vitamin D supplements available on the market, selecting the right one can be challenging. What factors should you consider when choosing a supplement?

Key Considerations

Form of calcium (e.g., calcium carbonate, calcium citrate)
Type of vitamin D (D2 or D3)
Dosage and serving size
Additional ingredients or fillers
Third-party testing and quality certifications
Brand reputation and customer reviews

Calcium citrate is often recommended for individuals with low stomach acid or those taking acid-reducing medications, as it’s more easily absorbed. Vitamin D3 (cholecalciferol) is generally preferred over D2 (ergocalciferol) due to its higher potency and better absorption.

Look for supplements that have been third-party tested for purity and potency. Organizations like USP (United States Pharmacopeia) and NSF International provide quality certifications for dietary supplements.

Common Formulations

Tablets
Chewable tablets
Gummies
Liquid formulations
Powders

Consider your personal preferences and any difficulty swallowing pills when choosing a formulation. Some individuals find chewable tablets or gummies more palatable and easier to take regularly.

Remember that the best supplement is one that you’ll consistently take as directed. If you have any doubts or questions about choosing the right calcium and vitamin D supplement, consult with a healthcare provider or registered dietitian for personalized recommendations.

Calcium and Vitamin D Combination (Calcium 500+D)

Brand Names:Calcarb with D, Calcet, Calcet Petites, Calcio Del Mar, Calcitrate with D, Calcium 500+D

By Julie Lynn MarksMedically Reviewed by Sanjai Sinha, MD

Reviewed: November 17, 2020

Calcium and vitamin D combination is a supplement that helps promote bone health, treat a calcium deficiency, and protect against osteoporosis.

Calcium is a natural mineral that plays a role in the body’s bone formation process. Vitamin D helps your body absorb calcium.

This supplement is sold under many different brands and is available as an over-the-counter (OTC) product.

uses

What is Calcium And Vitamin D Combination (Calcium 500+D) used for?

Osteoporosis
Dietary Supplement

warnings

What is the most important information I should know about Calcium And Vitamin D Combination (Calcium 500+D)?

Ask a doctor or pharmacist if this medicine is safe to use if you have:

kidney disease;
kidney stones;
heart disease;
cancer;
high levels of calcium in your blood;
circulation problems; or
a parathyroid gland disorder.

Ask a doctor before using this product if you are pregnant or breast-feeding. Your dose needs may be different during pregnancy or while you are nursing.

Side Effects

What are the side effects of Calcium And Vitamin D Combination (Calcium 500+D)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have signs of too much calcium in your body, such as:

nausea, vomiting, constipation;
increased thirst or urination;
muscle weakness, bone pain; or
confusion, lack of energy, or feeling tired.

Common side effects may include:

an irregular heartbeat;
weakness, drowsiness, headache;
dry mouth, or a metallic taste in your mouth; or
muscle or bone pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I take Calcium And Vitamin D Combination (Calcium 500+D) if I’m pregnant or breastfeeding?

Risk cannot be ruled out

Based on FDA pregnancy categories

Ask a doctor before using this product if you are pregnant or breast-feeding. Your dose needs may be different during pregnancy or while you are nursing.

Interactions

What drugs and food should I avoid while taking Calcium And Vitamin D Combination (Calcium 500+D)?

Ask a doctor or pharmacist before taking any multivitamins, mineral supplements, or antacids while you are taking calcium and vitamin D combination.

Dosage Guidelines & Tips

How to take Calcium And Vitamin D Combination (Calcium 500+D)?

Use Calcium And Vitamin D Combination (Calcium 500+D) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

What should I do if I missed a dose of Calcium And Vitamin D Combination (Calcium 500+D)?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

Overdose Signs

What happens if I overdose on Calcium And Vitamin D Combination (Calcium 500+D)?

If you think you or someone else may have overdosed on: Calcium And Vitamin D Combination (Calcium 500+D), call your doctor or the Poison Control center

(800) 222-1222

If someone collapses or isn’t breathing after taking Calcium And Vitamin D Combination (Calcium 500+D), call 911

911

What to Expect

You may experience mild side effects, such as minor gas or constipation, when taking calcium and vitamin D combination. If this occurs, try increasing your fluid intake or switching to a different brand.

Secondary Uses

Calcium and vitamin D combination may be used for purposes that aren’t listed in this guide.

Images

CALCET, MPC

Color: yellow

Shape: rectangular

Form: film coated

Imprint: CALCET, MPC

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Medical Disclaimer

Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. Cerner Multum™ provides the data within some of the Overview, Uses, Warnings, Side Effects, Pregnancy, Interactions, Dosage, Overdose, and Images sections. The information within all other sections is proprietary to Everyday Health.

Calcium and vitamin D combination Uses, Side Effects & Warnings

Generic name: calcium and vitamin D combination [ KAL-see-um-and-VYE-ta-min-D ]
Brand names: Calcitrate with D, Caltrate 600+D Soft Chews, Citracal + D, Os-Cal Extra D3, Oystercal-D,
… show all 50 brands
UpCal D, Os-Cal 250 with D, Oysco D, Dical-D, Calcet, Oyster Shell Calcium with Vitamin D, O-Cal-D, Oyster-D, Oyst-Cal-D, Caltro with Vitamin D, Oysco 500 with D, Oysco D with Calcium, Os-Cal with D, Calcarb with D, Posture-D H/P, Dical Captabs, Dicalphos plus D, Os-Cal 500 with D, Caltrate 600 with D Plus Soy, Caltrate Colon Health, Calvite P/D, Sedecal D, Chewable Calcium with Vitamin D, Osteocit D Plus, Os-Cal 500 + D, Citracal Petites, Citracal Creamy Bites, Citracal 250 mg + D, Calcio Del Mar, Citrus Calcium with Vitamin D, Calcium 600+D, Risacal-D, Liquid Calcium with Vitamin D, Citracal Maximum + D, Citracal Calcium + D Slow Release 1200, Citracal Calcium Gummies, Caltrate Gummy Bites, Super Calcium 600 + D3 400, Os-Cal Calcium+D3, Caltrate 600 + D, Citracal Regular, Calcet Petites, Calcium 500+D, D3 with Calcium, Calcium Plus Vitamin D3

Dosage forms: oral capsule (600 mg-5 mcg), oral powder for reconstitution (500 mg-12. 5 mcg/5 g), oral tablet ((as carbonate and lactate) 200 mg-6.25 mcg,
… show all 19 dosage forms
117 mg-3.325 mcg, 200 mg-6.25 mcg, 250 mg-3.125 mcg, 250 mg-5 mcg, 315 mg-5 mcg, 315 mg-6.25 mcg, 500 mg-10 mcg, 500 mg-15 mcg, 500 mg-3.125 mcg, 500 mg-5 mcg, 600 mg-10 mcg, 600 mg-20 mcg, 600 mg-3.125 mcg, 600 mg-5 mcg), oral tablet, chewable (250 mg-10 mcg; 250 mg-12.5 mcg; 500 mg-10 mcg; 500 mg-2.5 mcg; 600 mg-20 mcg), oral tablet, extended release (600 mg-12.5 mcg)

Drug class: Vitamin and mineral combinations

Medically reviewed by Drugs.com on May 22, 2023. Written by Cerner Multum.

What is calcium and vitamin D combination?

Calcium is a mineral that is necessary for many functions of the body, especially bone formation and maintenance. Vitamin D helps the body absorb calcium.

Calcium and vitamin D combination is used to treat or prevent a calcium deficiency.

There are many brands and forms of calcium and vitamin D combination available. Not all brands are listed on this leaflet.

Calcium and vitamin D combination may also be used for purposes not listed in this medication guide.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

Ask a doctor or pharmacist if calcium and vitamin D combination is safe to use if you have:

kidney disease;
kidney stones;
heart disease;
cancer;
high levels of calcium in your blood;
circulation problems; or
a parathyroid gland disorder.

Ask a doctor before using this product if you are pregnant or breast-feeding. Your dose needs may be different during pregnancy or while you are nursing.

How should I take calcium and vitamin D combination?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Check the label of your calcium and vitamin D combination product to see if it should be taken with or without food.

Take the regular tablet with a full glass of water.

The chewable tablet must be chewed before you swallow it.

Do not crush, chew, or break an extended-release tablet. Swallow it whole.

Calcium and vitamin D may be only part of a complete program of treatment that also includes dietary changes. Learn about the foods that contain calcium and vitamin D.

Your supplement dose may need to be adjusted as you make changes to your diet. Follow your doctor’s instructions very closely.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking calcium and vitamin D combination?

Ask a doctor or pharmacist before taking any multivitamins, mineral supplements, or antacids while you are taking calcium and vitamin D combination.

Calcium and vitamin D combination side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have signs of too much calcium in your body, such as:

nausea, vomiting, constipation;
increased thirst or urination;
muscle weakness, bone pain; or
confusion, lack of energy, or feeling tired.

Common side effects of calcium and vitamin D combination may include:

an irregular heartbeat;
weakness, drowsiness, headache;
dry mouth, or a metallic taste in your mouth; or
muscle or bone pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Calcium and vitamin D combination dosing information

Usual Adult Dose for Osteoporosis:

Calcium – General Range: 1000 mg to 1300 mg daily

Vitamin D – General Range: 200 international units to 800 international units daily

Note: While much larger vitamin D dosages have been recommended as a single agent, many calcium-vitamin D combination supplements will contain approximately 200 international units to 400 international units of vitamin D per dose.

Usual Adult Dose for Dietary Supplement:

Calcium – General Range: 1000 mg to 1300 mg daily

Vitamin D – General Range: 200 international units to 800 international units daily

What other drugs will affect calcium and vitamin D combination?

Calcium can make it harder for your body to absorb certain medicines, and some medicines can make it harder for your body to absorb vitamin D. If you take other medications, take them at least 2 hours before or 4 to 6 hours after you take calcium and vitamin D combination.

Other drugs may affect calcium and vitamin D combination, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

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Patient resources

Patient Information
Calcium and Vitamin D Chewable Tablets
Calcium and Vitamin D Liquid
Calcium and Vitamin D Powder

Other brands

Caltrate 600+D, Citracal + D, Os-Cal Calcium+D3, Os-Cal 500 Chewable, . .. +4 more

Related treatment guides

Osteoporosis
Dietary Supplementation

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

capsules, 166.7 mg + 66.7 IU
0.001 ‰

Analogs

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All forms of release, dosages, registration certificates, drug manufacturers, drug characteristics

Calcium-D3-MIC (capsules, 166.7 mg + 66.7 IU), instructions for medical use RU No. LSR-000019/09

Date last modified: 04/29/2021

Active substance
ATX
Nosological classification (ICD-10)
Pharmacological group
Dosage form
Compound
pharmachologic effect
Description of the dosage form
Pharmacokinetics
Indications
Contraindications
Use during pregnancy and lactation
Dosage and administration
Side effects
Interaction
Overdose
special instructions
Release form
Terms of dispensing from pharmacies
Storage conditions
Best before date
Order in Moscow pharmacies
Reviews

Active ingredient

Calcium carbonate + Colecalciferol (Calcium carbonate + Colecalciferol)

ATX

A12AX Calcium preparations in combination with vitamin D and/or other preparations

Nosological classification (ICD-10)

ICD-10 code list

E55 Vitamin D deficiency
E58 Nutritional calcium deficiency
M80. 9 Osteoporosis with pathological fracture, unspecified
M81.9Osteoporosis, unspecified

Pharmacological group

Bone and cartilage metabolism correctors in combinations

Vitamins and vitamin-like products in combinations

Dosage form

Capsules.

Composition

1
capsule contains:

Active ingredients:

Calcium
carbonate – 416.3 mg (in terms of calcium – 166.7 mg),
colecalciferol type 100 CWS – 0.667 mg (in terms of
colecalciferol – 0.001667 mg (66.7 IU)).

Composition
cholecalciferol type 100 CWS: cholecalciferol crystalline, α‑tocopherol,
soybean oil, corn starch, hydrolyzed gelatin, sucrose.

Excipient:

Starch
potato.

Composition of the gelatin capsule shell:

Composition
hard gelatin capsule bodies: gelatin, purified water, titanium dioxide
E171; composition of the cap of a hard gelatin capsule: gelatin, purified water,
titanium dioxide E171, alluring red dye E129, dye
quinoline yellow E104.

Combined
drug, the action of which is due to its constituent components.
Regulates the exchange of calcium and phosphate ions, reduces resorption and increases
bone density, compensates for the lack of calcium ions and vitamin D ₃
in the body, enhances the absorption of calcium ions in the intestine and reabsorption
phosphate in the kidneys, promotes bone mineralization.

Calcium
carbonate is involved in the formation of bone tissue, blood clotting,
in maintaining stable cardiac activity, in the implementation of processes
transmission of nerve impulses. Application of calcium and vitamin D ₃
prevents an increase in the production of parathyroid hormone, which is
stimulator of increased bone resorption.

Description of dosage form

Capsules
hard, gelatinous No. 0 cylindrical shape with hemispherical ends
with white body and orange lid.

Content
capsules – powder of white or almost white color.

Pharmacokinetics

Vitamin D ₃
absorbed in the small intestine. Calcium is absorbed in ionized form
in the proximal small intestine through active
transport mechanism.

Readings

–
Prevention and
treatment and deficiency of calcium and/or vitamin D ₃ .

–
With insufficient
intake of calcium and vitamin D ₃ into the body against the background
malnutrition.

–
With increased
body needs for calcium and vitamin D ₃
during pregnancy and breastfeeding, as well as in children over 12
years during a period of intensive growth.

–
Prevention and
as part of the complex therapy of osteoporosis (menopausal, senile,
“steroid”, idiopathic, etc. ).

Contraindications

–
Hypercalcemia
(increased concentration of calcium in the blood).

–
Hypercalciuria
(increased calcium in the urine).

–
Nephurolithiasis.

–
Hypervitaminosis
vitamin D ₃ .

–
Increased
sensitivity to the components of the drug.

–
severe renal
failure.

–
active form
tuberculosis.

–
Sarcoidosis.

–
Osteoporosis,
caused by immobilization.

–
Urolithiasis
disease.

–
Atherosclerosis.

–
Childhood
up to 12 years old.

With caution

Renal
insufficiency, benign granulomatosis, taking glycosides and thiazide
diuretics, pregnancy, lactation.

Use in pregnancy and lactation

Daily
the dose should not exceed 1500 mg calcium and 600 IU vitamin D ₃.
Hypercalcemia developing against the background of an overdose during pregnancy
can cause defects in the mental and physical development of the child.

Vitamin D ₃
and its metabolites can pass into breast milk, therefore, it is necessary to take into account
intake of calcium and vitamin D ₃ from other sources in the mother
and child. An overdose during pregnancy may lead to
mental and physical development of the child.

Dosage and administration

Information for healthcare professionals only.
Are you a healthcare professional?

Adults and children over 12:
2-3 capsules 2 times a day, morning and evening, mainly
while eating.

Side effects

Allergic
reactions, dysfunction of the gastrointestinal tract (constipation or diarrhea, flatulence,
nausea, abdominal pain), hypercalcemia and hypercalciuria (increased
calcium in blood or urine).