Side effects of calcium with vitamin d. Calcium and Vitamin D Combination: Uses, Side Effects, and Important Information

08.11.202019.07.2023 by alexxlab

What are the primary uses of calcium and vitamin D combination supplements. How can this supplement benefit bone health. What are the potential side effects of taking calcium with vitamin D. When should you consult a doctor before using these supplements.

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Understanding Calcium and Vitamin D Combination Supplements

Calcium and vitamin D combination supplements, such as Calcium 500+D, are widely used to support bone health and prevent various calcium-related conditions. These supplements combine two essential nutrients that work synergistically to maintain strong bones and overall health.

How do calcium and vitamin D work together? Calcium is a vital mineral for bone formation and strength, while vitamin D enhances the body’s ability to absorb calcium efficiently. This combination makes these supplements particularly effective in promoting skeletal health.

Common Brand Names

Calcarb with D
Calcet
Calcet Petites
Calcio Del Mar
Calcitrate with D
Calcium 500+D

These supplements are available over-the-counter, making them easily accessible for those looking to boost their calcium and vitamin D intake.

Primary Uses and Benefits of Calcium and Vitamin D Supplements

Why are calcium and vitamin D supplements recommended? These combinations serve several important purposes:

Promoting bone health
Treating calcium deficiency
Protecting against osteoporosis
Supporting overall skeletal strength

Do calcium and vitamin D supplements help with conditions other than bone health? While primarily known for their role in bone health, these supplements may also contribute to overall wellbeing. Some studies suggest potential benefits for heart health, muscle function, and immune system support, though more research is needed in these areas.

Important Considerations Before Taking Calcium and Vitamin D Supplements

Before incorporating calcium and vitamin D supplements into your routine, it’s crucial to consider certain factors. Are there any conditions that may make these supplements unsafe?

Consult a healthcare provider if you have:

Kidney disease
Kidney stones
Heart disease
Cancer
High levels of calcium in your blood
Circulation problems
Parathyroid gland disorders

Is it safe to take calcium and vitamin D supplements during pregnancy or while breastfeeding? While these nutrients are important during pregnancy and lactation, dosage needs may differ. Always consult with a healthcare provider to determine the appropriate intake for your specific situation.

Potential Side Effects of Calcium and Vitamin D Combination

As with any supplement, calcium and vitamin D combinations can cause side effects in some individuals. What are the most common side effects to watch out for?

Nausea
Vomiting
Constipation
Increased thirst or urination
Muscle weakness
Bone pain
Confusion
Fatigue

In rare cases, more severe side effects may occur. Seek immediate medical attention if you experience signs of an allergic reaction, such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat.

Less Common Side Effects

Some individuals may experience:

Irregular heartbeat
Drowsiness
Headache
Dry mouth
Metallic taste in the mouth

Are these side effects a cause for concern? While most side effects are mild and temporary, it’s important to monitor your body’s response to the supplement. If side effects persist or worsen, consult your healthcare provider.

Proper Dosage and Administration Guidelines

To maximize the benefits and minimize potential side effects, it’s crucial to follow proper dosage guidelines. How should you take calcium and vitamin D supplements?

Always follow the instructions on the product label or as prescribed by your healthcare provider. Typical recommendations include:

Taking the supplement with food to enhance absorption
Spreading doses throughout the day for better absorption
Avoiding taking large doses at once
Staying hydrated to prevent constipation

What should you do if you miss a dose? Take the missed dose as soon as you remember, unless it’s almost time for your next scheduled dose. In that case, skip the missed dose and resume your regular schedule. Never double up on doses to make up for a missed one.

Interactions with Other Medications and Supplements

Calcium and vitamin D supplements can interact with various medications and other supplements. Which interactions should you be aware of?

Antibiotics: Calcium may reduce the absorption of certain antibiotics
Bisphosphonates: Calcium can interfere with the absorption of these osteoporosis medications
Thyroid medications: Calcium may reduce their effectiveness
Iron supplements: Calcium can hinder iron absorption
Diuretics: Some diuretics can increase calcium levels in the blood

How can you minimize potential interactions? Always inform your healthcare provider about all medications and supplements you’re taking. They may recommend adjusting dosages or timing of administration to avoid interactions.

Special Precautions for Specific Groups

Certain groups may need to take special precautions when using calcium and vitamin D supplements. Who should be particularly cautious?

Elderly Individuals

Older adults may have different calcium and vitamin D requirements and may be more susceptible to side effects. Regular monitoring of calcium levels and kidney function may be necessary.

People with Absorption Issues

Individuals with conditions that affect nutrient absorption, such as Crohn’s disease or celiac disease, may need specialized formulations or adjusted dosages.

Those with a History of Kidney Stones

People prone to kidney stones should consult their healthcare provider before taking calcium supplements, as high doses may increase the risk of stone formation in some cases.

How can these groups safely incorporate calcium and vitamin D supplements? Work closely with a healthcare provider to determine the appropriate dosage and formulation based on individual health status and needs.

Alternatives to Calcium and Vitamin D Supplements

While supplements can be beneficial, obtaining nutrients from natural sources is often preferable. What are some alternatives to calcium and vitamin D supplements?

Calcium-Rich Foods

Dairy products (milk, yogurt, cheese)
Leafy green vegetables (kale, collard greens, spinach)
Fish with soft, edible bones (sardines, canned salmon)
Fortified plant-based milk alternatives
Tofu processed with calcium sulfate

Vitamin D Sources

Sunlight exposure (with proper sun protection)
Fatty fish (salmon, mackerel, tuna)
Egg yolks
Fortified foods (cereals, orange juice)
Mushrooms exposed to UV light

Can dietary sources provide sufficient calcium and vitamin D? For many people, a balanced diet can meet their calcium and vitamin D needs. However, some individuals may require supplements due to dietary restrictions, absorption issues, or increased needs.

Long-Term Considerations and Monitoring

When taking calcium and vitamin D supplements long-term, regular monitoring is essential. What should be monitored?

Blood calcium levels
Vitamin D levels
Kidney function
Bone density

How often should these factors be checked? The frequency of monitoring depends on individual health status and risk factors. Typically, annual check-ups are recommended, but some individuals may require more frequent monitoring.

Are there any long-term risks associated with calcium and vitamin D supplementation? While generally safe when taken as directed, excessive long-term use may increase the risk of kidney stones or cardiovascular issues in some individuals. Regular medical supervision can help mitigate these risks.

Emerging Research and Future Directions

The field of calcium and vitamin D supplementation continues to evolve as new research emerges. What are some recent developments and areas of ongoing study?

Personalized Dosing

Researchers are exploring ways to tailor calcium and vitamin D supplementation based on individual genetic profiles and health status. This personalized approach may optimize benefits while minimizing risks.

Bone Health Beyond Osteoporosis

Studies are investigating the potential role of calcium and vitamin D in preventing and managing other bone-related conditions, such as osteoarthritis and fracture healing.

Non-Skeletal Benefits

Ongoing research is examining the potential effects of calcium and vitamin D on various health aspects, including:

Cardiovascular health
Immune function
Metabolic health
Cancer prevention

How might these research directions impact future recommendations? As our understanding of calcium and vitamin D’s roles in the body expands, guidelines for supplementation may become more nuanced and tailored to individual health profiles and goals.

Making Informed Decisions About Calcium and Vitamin D Supplementation

Given the complexity surrounding calcium and vitamin D supplementation, how can individuals make informed decisions about their use?

Assess your dietary intake of calcium and vitamin D
Consider your risk factors for deficiency or related health conditions
Consult with a healthcare provider for personalized recommendations
Stay informed about current research and guidelines
Monitor your body’s response to supplementation
Regularly review and adjust your supplementation plan with your healthcare provider

By taking a thoughtful and informed approach, individuals can maximize the benefits of calcium and vitamin D supplementation while minimizing potential risks. Remember that supplements are meant to complement, not replace, a healthy diet and lifestyle.

As research continues to unfold, our understanding of calcium and vitamin D’s roles in health will undoubtedly evolve. Staying informed and maintaining open communication with healthcare providers will help ensure that supplementation strategies remain safe, effective, and tailored to individual needs.

Calcium and Vitamin D Combination (Calcium 500+D)

Brand Names:Calcarb with D, Calcet, Calcet Petites, Calcio Del Mar, Calcitrate with D, Calcium 500+D

By Julie Lynn MarksMedically Reviewed by Sanjai Sinha, MD

Reviewed: November 17, 2020

Calcium and vitamin D combination is a supplement that helps promote bone health, treat a calcium deficiency, and protect against osteoporosis.

Calcium is a natural mineral that plays a role in the body’s bone formation process. Vitamin D helps your body absorb calcium.

This supplement is sold under many different brands and is available as an over-the-counter (OTC) product.

uses

What is Calcium And Vitamin D Combination (Calcium 500+D) used for?

Osteoporosis
Dietary Supplement

warnings

What is the most important information I should know about Calcium And Vitamin D Combination (Calcium 500+D)?

Ask a doctor or pharmacist if this medicine is safe to use if you have:

kidney disease;
kidney stones;
heart disease;
cancer;
high levels of calcium in your blood;
circulation problems; or
a parathyroid gland disorder.

Ask a doctor before using this product if you are pregnant or breast-feeding. Your dose needs may be different during pregnancy or while you are nursing.

Side Effects

What are the side effects of Calcium And Vitamin D Combination (Calcium 500+D)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have signs of too much calcium in your body, such as:

nausea, vomiting, constipation;
increased thirst or urination;
muscle weakness, bone pain; or
confusion, lack of energy, or feeling tired.

Common side effects may include:

an irregular heartbeat;
weakness, drowsiness, headache;
dry mouth, or a metallic taste in your mouth; or
muscle or bone pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I take Calcium And Vitamin D Combination (Calcium 500+D) if I’m pregnant or breastfeeding?

Risk cannot be ruled out

Based on FDA pregnancy categories

Ask a doctor before using this product if you are pregnant or breast-feeding. Your dose needs may be different during pregnancy or while you are nursing.

Interactions

What drugs and food should I avoid while taking Calcium And Vitamin D Combination (Calcium 500+D)?

Ask a doctor or pharmacist before taking any multivitamins, mineral supplements, or antacids while you are taking calcium and vitamin D combination.

Dosage Guidelines & Tips

How to take Calcium And Vitamin D Combination (Calcium 500+D)?

Use Calcium And Vitamin D Combination (Calcium 500+D) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

What should I do if I missed a dose of Calcium And Vitamin D Combination (Calcium 500+D)?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

Overdose Signs

What happens if I overdose on Calcium And Vitamin D Combination (Calcium 500+D)?

If you think you or someone else may have overdosed on: Calcium And Vitamin D Combination (Calcium 500+D), call your doctor or the Poison Control center

(800) 222-1222

If someone collapses or isn’t breathing after taking Calcium And Vitamin D Combination (Calcium 500+D), call 911

911

What to Expect

You may experience mild side effects, such as minor gas or constipation, when taking calcium and vitamin D combination. If this occurs, try increasing your fluid intake or switching to a different brand.

Secondary Uses

Calcium and vitamin D combination may be used for purposes that aren’t listed in this guide.

Images

CALCET, MPC

Color: yellow

Shape: rectangular

Form: film coated

Imprint: CALCET, MPC

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Medical Disclaimer

Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. Cerner Multum™ provides the data within some of the Overview, Uses, Warnings, Side Effects, Pregnancy, Interactions, Dosage, Overdose, and Images sections. The information within all other sections is proprietary to Everyday Health.

Calcium and vitamin D combination Uses, Side Effects & Warnings

Generic name: calcium and vitamin D combination [ KAL-see-um-and-VYE-ta-min-D ]
Brand names: Calcitrate with D, Caltrate 600+D Soft Chews, Citracal + D, Os-Cal Extra D3, Oystercal-D,
… show all 50 brands
UpCal D, Os-Cal 250 with D, Oysco D, Dical-D, Calcet, Oyster Shell Calcium with Vitamin D, O-Cal-D, Oyster-D, Oyst-Cal-D, Caltro with Vitamin D, Oysco 500 with D, Oysco D with Calcium, Os-Cal with D, Calcarb with D, Posture-D H/P, Dical Captabs, Dicalphos plus D, Os-Cal 500 with D, Caltrate 600 with D Plus Soy, Caltrate Colon Health, Calvite P/D, Sedecal D, Chewable Calcium with Vitamin D, Osteocit D Plus, Os-Cal 500 + D, Citracal Petites, Citracal Creamy Bites, Citracal 250 mg + D, Calcio Del Mar, Citrus Calcium with Vitamin D, Calcium 600+D, Risacal-D, Liquid Calcium with Vitamin D, Citracal Maximum + D, Citracal Calcium + D Slow Release 1200, Citracal Calcium Gummies, Caltrate Gummy Bites, Super Calcium 600 + D3 400, Os-Cal Calcium+D3, Caltrate 600 + D, Citracal Regular, Calcet Petites, Calcium 500+D, D3 with Calcium, Calcium Plus Vitamin D3

Dosage forms: oral capsule (600 mg-5 mcg), oral powder for reconstitution (500 mg-12. 5 mcg/5 g), oral tablet ((as carbonate and lactate) 200 mg-6.25 mcg,
… show all 19 dosage forms
117 mg-3.325 mcg, 200 mg-6.25 mcg, 250 mg-3.125 mcg, 250 mg-5 mcg, 315 mg-5 mcg, 315 mg-6.25 mcg, 500 mg-10 mcg, 500 mg-15 mcg, 500 mg-3.125 mcg, 500 mg-5 mcg, 600 mg-10 mcg, 600 mg-20 mcg, 600 mg-3.125 mcg, 600 mg-5 mcg), oral tablet, chewable (250 mg-10 mcg; 250 mg-12.5 mcg; 500 mg-10 mcg; 500 mg-2.5 mcg; 600 mg-20 mcg), oral tablet, extended release (600 mg-12.5 mcg)

Drug class: Vitamin and mineral combinations

Medically reviewed by Drugs.com on May 22, 2023. Written by Cerner Multum.

What is calcium and vitamin D combination?

Calcium is a mineral that is necessary for many functions of the body, especially bone formation and maintenance. Vitamin D helps the body absorb calcium.

Calcium and vitamin D combination is used to treat or prevent a calcium deficiency.

There are many brands and forms of calcium and vitamin D combination available. Not all brands are listed on this leaflet.

Calcium and vitamin D combination may also be used for purposes not listed in this medication guide.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

Ask a doctor or pharmacist if calcium and vitamin D combination is safe to use if you have:

kidney disease;
kidney stones;
heart disease;
cancer;
high levels of calcium in your blood;
circulation problems; or
a parathyroid gland disorder.

Ask a doctor before using this product if you are pregnant or breast-feeding. Your dose needs may be different during pregnancy or while you are nursing.

How should I take calcium and vitamin D combination?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Check the label of your calcium and vitamin D combination product to see if it should be taken with or without food.

Take the regular tablet with a full glass of water.

The chewable tablet must be chewed before you swallow it.

Do not crush, chew, or break an extended-release tablet. Swallow it whole.

Calcium and vitamin D may be only part of a complete program of treatment that also includes dietary changes. Learn about the foods that contain calcium and vitamin D.

Your supplement dose may need to be adjusted as you make changes to your diet. Follow your doctor’s instructions very closely.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking calcium and vitamin D combination?

Ask a doctor or pharmacist before taking any multivitamins, mineral supplements, or antacids while you are taking calcium and vitamin D combination.

Calcium and vitamin D combination side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have signs of too much calcium in your body, such as:

nausea, vomiting, constipation;
increased thirst or urination;
muscle weakness, bone pain; or
confusion, lack of energy, or feeling tired.

Common side effects of calcium and vitamin D combination may include:

an irregular heartbeat;
weakness, drowsiness, headache;
dry mouth, or a metallic taste in your mouth; or
muscle or bone pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Calcium and vitamin D combination dosing information

Usual Adult Dose for Osteoporosis:

Calcium – General Range: 1000 mg to 1300 mg daily

Vitamin D – General Range: 200 international units to 800 international units daily

Note: While much larger vitamin D dosages have been recommended as a single agent, many calcium-vitamin D combination supplements will contain approximately 200 international units to 400 international units of vitamin D per dose.

Usual Adult Dose for Dietary Supplement:

Calcium – General Range: 1000 mg to 1300 mg daily

Vitamin D – General Range: 200 international units to 800 international units daily

What other drugs will affect calcium and vitamin D combination?

Calcium can make it harder for your body to absorb certain medicines, and some medicines can make it harder for your body to absorb vitamin D. If you take other medications, take them at least 2 hours before or 4 to 6 hours after you take calcium and vitamin D combination.

Other drugs may affect calcium and vitamin D combination, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

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Drug class: vitamin and mineral combinations
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Patient resources

Patient Information
Calcium and Vitamin D Chewable Tablets
Calcium and Vitamin D Liquid
Calcium and Vitamin D Powder

Other brands

Caltrate 600+D, Citracal + D, Oystercal-D, Os-Cal Calcium+D3, . .. +4 more

Related treatment guides

Dietary Supplementation
Osteoporosis

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Calcium-D3-MIC – instructions for use, doses, side effects, reviews of the drug: capsules, 166.7 mg + 66.7 IU

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Calcium-D3-MIK (capsules, 166. 7 mg + 66.7 IU), instructions for medical use RU No. LSR-000019/09

Active substance
ATX
Nosological classification (ICD-10)
Pharmacological group
Dosage form
Compound
pharmachologic effect
Description of the dosage form
Pharmacokinetics
Indications
Contraindications
Use during pregnancy and lactation
Dosage and administration
Side effects
Interaction
Overdose
special instructions
Release form
Terms of dispensing from pharmacies
Storage conditions
Best before date
Order in Moscow pharmacies
Reviews

Active ingredient

Calcium carbonate + Colecalciferol (Calcium carbonate + Colecalciferol)

ATX

A12AX Calcium preparations in combination with vitamin D and/or other preparations

Nosological classification (ICD-10)

ICD-10 code list

Pharmacological group

Vitamins and vitamin-like products in combinations

Bone and cartilage metabolism correctors in combinations

Dosage form

Capsules.

Composition

1
capsule contains:

Active ingredients:

Calcium
carbonate – 416.3 mg (in terms of calcium – 166.7 mg),
colecalciferol type 100 CWS – 0.667 mg (in terms of
colecalciferol – 0.001667 mg (66.7 IU)).

Composition
cholecalciferol type 100 CWS: cholecalciferol crystalline, α‑tocopherol,
soybean oil, corn starch, hydrolyzed gelatin, sucrose.

Excipient:

Starch
potato.

Composition of the gelatin capsule shell:

Composition
hard gelatin capsule bodies: gelatin, purified water, titanium dioxide
E171; composition of the cap of a hard gelatin capsule: gelatin, purified water,
titanium dioxide E171, alluring red dye E129, dye
quinoline yellow E104.

Combined
drug, the action of which is due to its constituent components.
Regulates the exchange of calcium and phosphate ions, reduces resorption and increases
bone density, compensates for the lack of calcium ions and vitamin D ₃
in the body, enhances the absorption of calcium ions in the intestine and reabsorption
phosphate in the kidneys, promotes bone mineralization.

Calcium
carbonate is involved in the formation of bone tissue, blood clotting,
in maintaining stable cardiac activity, in the implementation of processes
transmission of nerve impulses. The use of calcium and vitamin D ₃
prevents an increase in the production of parathyroid hormone, which is
stimulator of increased bone resorption.

Description of dosage form

Capsules
hard, gelatinous No. 0 cylindrical shape with hemispherical ends
with white body and orange lid.

Content
capsules – powder of white or almost white color.

Pharmacokinetics

Vitamin D ₃
absorbed in the small intestine. Calcium is absorbed in ionized form
in the proximal small intestine through active
transport mechanism.

Readings

–
Prevention and
treatment and deficiency of calcium and/or vitamin D ₃ .

–
With insufficient
intake of calcium and vitamin D ₃ into the body against the background
malnutrition.

–
With increased
body needs for calcium and vitamin D ₃
during pregnancy and breastfeeding, as well as in children over 12
years during a period of intensive growth.

–
Prevention and
as part of the complex therapy of osteoporosis (menopausal, senile,
“steroid”, idiopathic, etc.).

Contraindications

–
Hypercalcemia
(increased concentration of calcium in the blood).

–
Hypercalciuria
(increased calcium in the urine).

–
Nephurolithiasis.

–
Hypervitaminosis
vitamin D ₃ .

–
Increased
sensitivity to the components of the drug.

–
severe renal
failure.

–
active form
tuberculosis.

–
Sarcoidosis.

–
Osteoporosis,
caused by immobilization.

–
Urolithiasis
disease.

–
Atherosclerosis.

–
Childhood
up to 12 years old.

With caution

Renal
insufficiency, benign granulomatosis, taking glycosides and thiazide
diuretics, pregnancy, lactation.

Use in pregnancy and lactation

Daily
the dose should not exceed 1500 mg calcium and 600 IU vitamin D ₃.
Hypercalcemia developing against the background of an overdose during pregnancy
can cause defects in the mental and physical development of the child.

Vitamin D ₃
and its metabolites can pass into breast milk, therefore, it is necessary to take into account
intake of calcium and vitamin D ₃ from other sources in the mother
and child. An overdose during pregnancy may lead to
mental and physical development of the child.

Dosage and administration

Information for healthcare professionals only.
Are you a healthcare professional?

Adults and children over 12:
2-3 capsules 2 times a day, morning and evening, mainly
while eating.

Side effects

Allergic
reactions, dysfunction of the gastrointestinal tract (constipation or diarrhea, flatulence,
nausea, abdominal pain), hypercalcemia and hypercalciuria (increased
calcium in blood or urine).