What are the common side effects of cefprozil 250 mg. How should cefprozil be taken properly. What precautions should be considered when using cefprozil. Who should not take cefprozil.

Understanding Cefprozil: An Antibiotic for Bacterial Infections

Cefprozil is a powerful antibiotic belonging to the cephalosporin family. It’s primarily used to combat various bacterial infections, offering relief to patients suffering from conditions affecting the throat, ear, sinus, skin, and bladder. The medication works by weakening the cell walls of bacteria, effectively eliminating the cause of infection.

Cefprozil is available in different forms and dosages, with the 250 mg option being a common prescription. It’s crucial to understand that while this medication can be highly effective, it should only be used under the guidance of a healthcare professional.

Proper Usage and Dosage Guidelines for Cefprozil

The correct dosage of cefprozil varies depending on the patient’s age, weight, and the specific condition being treated. For adults and adolescents 13 years and older, the typical dose ranges from 250 mg to 500 mg, taken every 12 to 24 hours. Children’s dosages are calculated based on body weight, usually between 7.5 mg to 15 mg per kilogram, administered every 12 hours for most infections.

Can cefprozil be taken with food? Yes, cefprozil can be taken with or without food, providing flexibility for patients. However, it’s essential to complete the entire course of antibiotics, even if symptoms improve, to prevent the recurrence of infection and reduce the risk of antibiotic resistance.

Key Points for Taking Cefprozil:

• Follow your doctor’s prescribed dosage carefully
• Take the medication at regular intervals
• Complete the entire course of antibiotics
• Store liquid forms in the refrigerator
• Keep tablets at room temperature

Common Side Effects of Cefprozil 250 mg

While cefprozil is generally well-tolerated, some patients may experience side effects. It’s important to be aware of these potential reactions and to consult a healthcare provider if they become severe or persistent.

What are the most frequently reported side effects of cefprozil? The most common side effects include:

• Mild diarrhea
• Dizziness
• Drowsiness
• Headache
• Nausea
• Mild stomach cramps
• Vaginal itching or discharge
• Vomiting

These side effects are typically mild and often resolve on their own. However, if they persist or worsen, it’s advisable to seek medical attention.

Serious Side Effects and When to Seek Medical Help

While rare, some patients may experience more severe side effects that require immediate medical attention. These serious side effects can include:

• Confusion
• Severe itchiness
• Intense abdominal or stomach cramps
• Signs of allergic reaction (e.g., rash, swelling, difficulty breathing)

How quickly should you seek medical help if experiencing serious side effects? If you notice any of these severe reactions, it’s crucial to contact your healthcare provider immediately or seek emergency medical attention.

Contraindications: Who Should Avoid Cefprozil?

Cefprozil is not suitable for everyone. Certain individuals should avoid this medication due to potential risks or interactions. You should not take cefprozil if you:

• Are allergic to cefprozil or any of its ingredients
• Have a known allergy to cephalosporin antibiotics

It’s crucial to inform your healthcare provider about any allergies or sensitivities you may have before starting cefprozil treatment. This information helps prevent potentially dangerous reactions and ensures your safety during the course of antibiotics.

Interactions and Precautions with Cefprozil

When taking cefprozil, it’s important to be aware of potential interactions with other medications or substances. Some interactions may affect the efficacy of cefprozil or increase the risk of side effects.

Potential Interactions to Consider:

• Other antibiotics
• Blood thinners
• Probenecid (used to treat gout)
• Certain oral contraceptives

Always inform your healthcare provider about all medications, supplements, and herbal products you’re taking to ensure safe and effective treatment with cefprozil.

Special Considerations for Pregnant and Breastfeeding Women

The safety of cefprozil during pregnancy and breastfeeding is an important consideration. While cefprozil is generally considered safe for use during pregnancy, it’s crucial to discuss the potential risks and benefits with your healthcare provider.

Is cefprozil safe for breastfeeding mothers? Cefprozil can pass into breast milk in small amounts. While it’s unlikely to harm a nursing infant, it’s essential to consult with your doctor before using this medication while breastfeeding. They can provide guidance on whether the benefits outweigh any potential risks.

Proper Storage and Disposal of Cefprozil

Correct storage and disposal of cefprozil are crucial for maintaining its effectiveness and preventing accidental ingestion. Here are some guidelines to follow:

• Store liquid forms in the refrigerator
• Keep tablets at room temperature
• Keep all forms out of reach of children
• Dispose of unused medication after 14 days
• Do not flush medication down the toilet or sink
• Consult your pharmacist for proper disposal methods

How long can you keep cefprozil after opening? For liquid forms, discard any remaining medication after 14 days, even if it hasn’t expired. Always check the expiration date on the packaging and never use expired antibiotics.

Monitoring Your Progress on Cefprozil

While taking cefprozil, it’s important to monitor your progress and be aware of any changes in your condition. Regular check-ins with your healthcare provider can help ensure the medication is working effectively and address any concerns that may arise during treatment.

Signs of Improvement to Look For:

• Reduction in symptoms
• Improved overall feeling of wellness
• Decreased fever or pain
• Clearing of infection site (for skin infections)

If you don’t notice improvement after a few days of treatment, or if your symptoms worsen, contact your healthcare provider. They may need to adjust your treatment plan or consider alternative antibiotics.

Long-term Considerations and Antibiotic Resistance

The responsible use of antibiotics like cefprozil is crucial in combating the growing threat of antibiotic resistance. Overuse or misuse of antibiotics can lead to the development of resistant bacteria, making infections harder to treat in the future.

How can patients help prevent antibiotic resistance? Here are some key practices:

• Only use antibiotics when prescribed by a healthcare professional
• Complete the entire course of antibiotics as directed
• Never share antibiotics with others or use leftover antibiotics
• Practice good hygiene to prevent the spread of infections

By using cefprozil responsibly and following your healthcare provider’s instructions, you can contribute to the fight against antibiotic resistance while effectively treating your infection.

Alternative Treatments and Complementary Approaches

While cefprozil is an effective treatment for many bacterial infections, it’s not always the only option. In some cases, alternative antibiotics or complementary approaches may be considered, especially for patients who cannot tolerate cefprozil or have allergies to cephalosporins.

Potential Alternatives to Consider:

• Other classes of antibiotics (e.g., penicillins, macrolides)
• Topical treatments for certain skin infections
• Supportive care measures to alleviate symptoms
• Probiotics to support gut health during antibiotic treatment

Always consult with your healthcare provider before considering any alternative treatments or complementary approaches. They can provide guidance on the most appropriate options for your specific condition and medical history.

Managing Side Effects and Improving Tolerability

While side effects from cefprozil are often mild, some patients may experience discomfort that affects their quality of life during treatment. Understanding how to manage these side effects can improve the overall experience and increase the likelihood of completing the full course of antibiotics.

Tips for Managing Common Side Effects:

• Take the medication with food to reduce stomach upset
• Stay hydrated to help alleviate diarrhea
• Use probiotic supplements to support gut health
• Get plenty of rest to combat fatigue or drowsiness
• Avoid alcohol and caffeine if experiencing dizziness

If side effects persist or worsen despite these measures, it’s important to consult your healthcare provider. They may be able to adjust your dosage or recommend additional supportive treatments to improve tolerability.

The Role of Cefprozil in Treating Specific Infections

Cefprozil is effective against a wide range of bacterial infections, but it’s particularly useful for certain conditions. Understanding its specific applications can help patients and healthcare providers make informed decisions about treatment options.

Common Infections Treated with Cefprozil:

• Strep throat
• Sinus infections
• Ear infections (otitis media)
• Skin and soft tissue infections
• Uncomplicated urinary tract infections

What makes cefprozil an effective choice for these infections? Its broad-spectrum activity against many common bacteria, combined with its generally good tolerability profile, makes it a versatile option for treating a variety of infections in both adults and children.

Cefprozil and Its Impact on Gut Health

Like all antibiotics, cefprozil can have an impact on the balance of bacteria in the gut microbiome. While this is often a necessary trade-off in treating bacterial infections, it’s important to be aware of the potential effects and take steps to support gut health during and after treatment.

Strategies for Supporting Gut Health:

• Consume probiotic-rich foods or supplements
• Eat a diverse diet with plenty of fiber
• Stay hydrated
• Consider prebiotic foods to support beneficial bacteria
• Avoid unnecessary use of antibiotics

How long does it take for gut flora to recover after antibiotic treatment? While individual experiences may vary, it typically takes several weeks to several months for the gut microbiome to fully recover. Supporting your gut health during this time can help speed up the process and minimize potential digestive issues.

Patient Education and Empowerment

Educating patients about cefprozil and antibiotic use, in general, is crucial for promoting responsible use and improving treatment outcomes. When patients understand their medication and its importance, they’re more likely to adhere to the prescribed regimen and report any concerns to their healthcare provider promptly.

Key Points for Patient Education:

• The importance of completing the full course of antibiotics
• Potential side effects and when to seek medical attention
• Proper storage and disposal of medication
• The role of antibiotics in treating bacterial (not viral) infections
• The importance of follow-up appointments and communication with healthcare providers

By empowering patients with knowledge about cefprozil and antibiotic use, healthcare providers can foster a collaborative approach to treatment and improve overall health outcomes.

Future Developments and Research in Antibiotic Therapy

As antibiotic resistance continues to be a global health concern, ongoing research into new antibiotics and treatment strategies is crucial. While cefprozil remains an effective treatment for many infections, the medical community is always looking for ways to improve antibiotic therapy and combat resistance.

Areas of Current Research and Development:

• New classes of antibiotics
• Combination therapies to enhance effectiveness
• Targeted delivery systems for antibiotics
• Alternative approaches to treating bacterial infections
• Improved diagnostic tools for identifying bacterial infections

What can patients do to support antibiotic research and development? Participating in clinical trials, advocating for increased funding for antibiotic research, and practicing responsible antibiotic use are all ways individuals can contribute to the ongoing effort to improve antibiotic therapy.

As we continue to navigate the challenges of bacterial infections and antibiotic resistance, medications like cefprozil play a crucial role in maintaining public health. By understanding its uses, benefits, and potential side effects, patients and healthcare providers can work together to ensure the most effective and responsible use of this important antibiotic.

RAN-Cefprozil – Uses, Side Effects, Interactions

How does this medication work? What will it do for me?

Cefprozil is an antibiotic that belongs to the family of medications known as cephalosporins. It is used to treat certain types of infections caused by bacteria. It is most commonly used to treat infections of the throat, ear, sinus, skin, and bladder. It works by weakening the cell walls of the bacteria causing the infection, thereby killing the bacteria.

This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor.  Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

What form(s) does this medication come in?

RAN-Cefprozil is no longer being manufactured for sale in Canada. For brands that may still be available, search under cefprozil. This article is being kept available for reference purposes only. If you are using this medication, speak with your doctor or pharmacist for information about your treatment options.

How should I use this medication?

Adults: The recommended dose for adults and adolescents 13 years and older is 250 mg to 500 mg every 12 to 24 hours. The exact dose depends on the condition being treated.

Children: The recommended children’s dose is 7. 5 mg to 15 mg per kilogram of body weight every 12 hours to treat throat, sinus, or ear infections. For skin infections, the recommended dose is 20 mg per kilogram every 24 hours. The exact dose depends on the condition being treated.

Cefprozil can be taken with or without food.

Finish all of this medication, even you start to feel better. This will reduce the chance of the infection returning.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.  Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store liquid forms of this medication in the refrigerator, out of reach and sight of children. Any medication remaining after 14 days should be safely discarded.

Tablets should be stored at room temperature, and kept out of reach and sight of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Who should NOT take this medication?

Do not take cefprozil if you:

• are allergic to cefprozil or any ingredients of the medication
• are allergic to cephalosporin antibiotics

What side effects are possible with this medication?

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

• mild diarrhea
• dizziness
• drowsiness
• headache
• nausea
• stomach cramps (mild)
• vaginal itching or discharge
• vomiting

Although most of these side effects listed below don’t happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• confusion
• itchiness
• severe abdominal or stomach cramps and pain
• signs of liver problems (e.g., nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools)

Stop taking the medication and seek immediate medical attention if any of the following occur:

• diarrhea (watery and severe, which may also be bloody)
• seizures
• signs of a serious allergic reaction (i.e., abdominal cramps, difficulty breathing, nausea and vomiting, or swelling of the face and throat)
• symptoms of a severe skin rash (such as blistering, peeling, a rash covering a large area of the body, a rash that spreads quickly, or a rash combined with fever or discomfort)

Some people may experience side effects other than those listed.  Check with your doctor if you notice any symptom that worries you while you are taking this medication.

Are there any other precautions or warnings for this medication?

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Allergy: Before starting treatment with cefprozil, inform your doctor about any adverse reactions you have had to medications, especially cefprozil, cephalosporins, and penicillins. Some people allergic to penicillin may also be allergic to cephalosporins such as cefprozil. If you have an allergic reaction, contact a doctor.

Antibiotic-associated colitis: Like other antibiotics, this medication may cause a potentially dangerous condition called antibiotic-associated colitis (or pseudomembranous colitis). Symptoms include severe, watery diarrhea that may be bloody. If you notice these symptoms, stop taking cefprozil and contact your doctor as soon as possible.

Bacterial resistance: Misuse of an antibiotic such as cefprozil may lead to the growth of resistant bacteria that will not be killed by the antibiotic. If this happens, the antibiotic may not work for you in the future. Although you may begin to feel better when you first start taking cefprozil, you need to take all of the medication exactly as prescribed by your doctor to finish ridding your body of the infection and to prevent resistant bacteria from taking hold. Do not take cefprozil or other antibiotics to treat a viral infection such as the common cold; antibiotics do not kill viruses, and using them to treat viral infections can lead to the growth of resistant bacteria.

Kidney function: Kidney disease and decreased kidney function may cause this medication to build up in the body, causing side effects. People with kidney disease or reduced kidney function should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Overgrowth of organisms: Prolonged or repeated use of cefprozil may result in an overgrowth of bacteria or fungi and organisms that are not killed by the medication. This can cause problems such as yeast infections.

Skin reactions: Rarely, people taking cefprozil experience a severe skin reaction that can be life-threatening. These reactions may start as a skin rash that blisters, sores on the lips, eyes, or covers a large area of the body. It can develop into an exfoliating skin condition, with peeling, shedding, or scaling of the skin. If you experience any of these symptoms, or any other unusual skin reaction of the skin, contact your doctor immediately.

Pregnancy: It is not known if cefprozil is safe for use by pregnant women. This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.

Breast-feeding: This medication passes into breast milk. If you are breast-feeding and are taking cefprozil, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: It is not known if cefprozil is safe for children under 6 months of age.

What other drugs could interact with this medication?

There may be an interaction between cefprozil and any of the following:

• aminoglycoside antibiotics (e.g., gentamicin, tobramycin)
• BCG vaccine
• cholera vaccine
• furosemide
• monoclonal antibodies (e.g., atezolizumab, nivolumab)
• paromomycin
• probenecid
• sodium picosulfate
• typhoid vaccine
• warfarin

If you are taking any of these medications, speak with your doctor or pharmacist.  Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

All material copyright MediResource Inc. 1996 – 2023. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/drug/getdrug/RAN-Cefprozil

Cefprozil Oral Tablet 250 mg, 500 mg – Health Information Library

For treating bacterial infection.

Generic Name: Cefprozil

Instructions

You may take with food to prevent stomach upset.

This medicine will work best if you take it at about the same time every day.

Store at room temperature away from heat, light, and moisture. Do not keep in the bathroom.

If you forget to take a dose on time, take it as soon as you remember. If it is almost time for the next dose, do not take the missed dose. Return to your normal schedule. Do not take 2 doses at one time.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor if symptoms do not get better or if they get worse.

Keep using this medicine for the full number of days that it is prescribed. Do not stop the medicine even if you start to feel better.

If you have diabetes and use urine glucose tests, this medicine may cause incorrect results. Please check with your doctor before making any changes to your diabetes treatment plan.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Do not use the medication any more than instructed.

Your ability to stay alert or to react quickly may be impaired by this medicine. Do not drive or operate machinery until you know how this medicine will affect you.

Please check with your doctor before drinking alcohol while on this medicine.

Contact your doctor if you notice a change in the amount or darkening of your urine.

Speak with your health care provider before receiving any vaccinations.

Please tell your doctor if you have moderate to severe diarrhea while on this medicine. Do not treat the diarrhea with over-the-counter diarrhea medicine.

Tell the doctor or pharmacist if you are pregnant, planning to be pregnant, or breastfeeding.

Do not share this medicine with anyone who has not been prescribed this medicine.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

• diarrhea
• dizziness
• nausea
• stomach upset or abdominal pain
• yeast infection of mouth
• vaginal itching or yeast infection

Call your doctor or get medical help right away if you notice any of these more serious side effects:

• confusion
• severe, watery or bloody diarrhea
• signs of kidney damage (such as change in urine color or bubbly urine)
• blistering or peeling of the skin
• severe stomach or bowel pain

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.

IMPORTANT NOTE: This document tells you briefly how to take your medicine, but it does not tell you all there is to know about it. Your doctor or pharmacist may give you other documents about your medicine. Please talk to them if you have any questions. Always follow their advice.

There is a more complete description of this medicine available in English. Scan this code on your smartphone or tablet or use the web address below. You can also ask your pharmacist for a printout. If you have any questions, please ask your pharmacist.

The display and use of this drug information is subject to Terms of Use.

https://api.meducation.com/V2.0/fdbpem/4011

Copyright(c) 2023 First Databank, Inc.

Selected from data included with permission and copyright by First DataBank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

Conditions of Use: The information in this database is intended to supplement, not substitute for the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express Terms of Use.

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Health Information Library

instructions for use, price, analogues, composition, indications

Before starting treatment with cephalosporins, it is necessary to exclude the presence of hypersensitivity reactions to cephalosporins, penicillins and other drugs in history.

Up to 10% of patients with a history of penicillin allergy may develop cross-sensitivity to other β-lactam antibiotics.

Treatment with cefprozil should be discontinued if an allergic reaction to cefprozil develops. Serious hypersensitivity reactions may require the use of epinephrine and other emergency measures, including intravenous administration of electrolytes, antihistamines, corticosteroids, pressor amines, airway management, oxygen if indicated.

As with other antibiotics, long-term treatment with cefprozil can lead to superinfection caused by Clostridium difficile, diarrhea, colitis, and even death. The drug is canceled, electrolytes, plasma substitutes, antibiotics for the treatment of Clostridium difficile are prescribed, according to indications, a surgeon’s consultation may be required.

Patients with established or suspected renal insufficiency require clinical evaluation and laboratory testing before and during therapy. The daily dose of the drug should be adjusted. Caution is required when taking cefprozil and a strong diuretic at the same time, as the latter may worsen renal function.

Administration of cefprozil in the absence of proven or suspected bacterial infection or prophylactic administration is unlikely to benefit the patient and increases the risk of developing resistant bacteria.

Cefprozil should be used with caution in patients with a history of gastrointestinal disease, particularly colitis.

Prolonged use of the drug may lead to overgrowth of resistant organisms. Careful monitoring of the patient is necessary. If superinfection develops during therapy, appropriate measures should be taken. Cefprozil should not be used in patients with a history of cephalosporin-induced hemolytic anemia

Possible positive Coombs test during treatment with cephalosporin antibiotics.

Use during pregnancy

Category B.

In reproduction studies in rabbits, mice and rats, administration of oral doses of cefprozil at 0. 8, 8.5 and 18.5 times the maximum daily dose in humans (1000 mg ), showed no harm to the fetus. There are no adequate and well-controlled studies in pregnant women. Since the results of animal studies cannot always be extrapolated to humans, the use of the drug during pregnancy should be limited to cases of emergency.

Nursing mothers

Small amounts of cefprozil are found in breast milk (> 0.3% of the administered dose) after a single 1 g dose in lactating women. The average level in milk is 0.25 to 3.3 mcg/mL. Caution is required when taking cefprozil to nursing mothers, as the effect of cefprozil on nursing infants is not known.

Influence on the ability to control drive a car and potentially dangerous machinery

Care must be taken when driving a car and engaging in other potentially hazardous activities that require increased attention and speed of psychomotor reactions.

Interaction with other drugs media 90 035 tvami

Cases of nephrotoxicity have been reported with the simultaneous use of aminoglycoside antibiotics and cephalosporin antibiotics.

Co-administration of probenecid resulted in a doubling of the AUC of cefprozil.

The bioavailability of cefprozil is not affected by concomitant use of antacids. Interference with laboratory results

Cephalosporin antibiotics may give a false positive reaction for urinary glucose in the copper reduction test (Benedict’s or Felling’s solution), but not in tests based on enzymatic detection of glucosuria.

Storage conditions and shelf life

Store below 25°C in original packaging. Keep away from children.

Procef (Cefprozil) – instructions for use, dosage, composition, analogues, side effects / Pillintrip

Page reviewed by pharmacist Fedorchenko Olga Valerievna Last update 2022-04-04

Attention!
The information on this page is for healthcare professionals only!
The information is collected from open sources and may contain significant errors!
Be careful and double-check all the information on this page!

Top 20 medicines with the same ingredients: prozil)CefnorCefpro

Top 20 drugs with the same use:

BiaxinCepiusSandoz CefprozilZilrozPrefixCefipraProzidilZilcefAuroprozilRadacefeSerozilCefgram (Cefprozil)ErasefNatrofenPricefilTeliomonUltracef ( Cefprozil)Xi NengYinlishuYuanrui

Therapeutic indications

Description Therapeutic indications Procef (Cefprozil) is an automatic translation from the original language.
Do not use this information for any medical prescription or manipulation under any circumstances.
Be sure to read the original instructions for the medicine from the package.
This description may contain numerous errors due to automatic translation!
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Procef (Cefprozil) (cefprozil) is indicated for the treatment of patients with mild to moderate infections caused by susceptible strains of the designated organisms under the conditions listed below:

Upper respiratory tract

Pharyngitis/tonsillitis called Streptococcus pyogenes .

NOTE. A common drug of choice in the treatment and prevention of streptococcal infections, including the prevention of rheumatic fever, is penicillin, which is administered intramuscularly. Cefprozil is generally effective in repaying Streptococcus pyogenes from nasopharynx; however, there are currently no significant data on the effectiveness of cefprozil in the subsequent prevention of rheumatic fever.

Otitis Media is caused by Streptococcus pneumoniae, Haemophilus influenzae (including β-lactamase producing strains) and Moraxella (Branhamella) catarralis (including β-lactamase producing strains). (See CLINICAL STUDIES .)

NOTE: in the treatment of otitis media caused by β-lactamase producing organisms, cefprozil had bacteriological eradication rates that were slightly lower than in the product that contained the specific β-lactamase inhibitor. When considering the use of cefprozil, lower overall eradication rates must be offset by patterns of susceptibility in common microbes in a given geographic area and an increased potential for toxicity for products containing β-lactamase inhibitors.

Acute sinusitis is caused by Streptococcus pneumoniae, Haemophilus influenzae (including β-lactamase producing strains) and Moraxella (Branhamella) catarralis (including β-lactamase producing strains).

Lower respiratory tract

Secondary bacterial infection Acute bronchitis and acute bacterial exacerbation Chronic bronchitis caused by Streptococcus pneumoniae, Haemophilus influenzae (including β-lactamase producing strains) and Moraxella (Branhamella) catarralis (including β-lactamase producing strains).

Skin and skin structure

Uncomplicated skin and skin structure infections caused by Staphylococcus aureus (including penicillinase-producing strains) and Streptococcus pyogenes ABSCESIS usually requires surgical drainage.

To reduce the development of drug-resistant bacteria and maintain the efficacy of Procef (Cefprozil) (cefprozil) and other antibacterial drugs, Procef (Cefprozil) (cefprozil) should only be used to treat or prevent infections that have been shown to be caused by susceptible bacteria. If culture and susceptibility information is available, you should consider choosing or changing antibiotic therapy. In the absence of such data, local epidemiological and susceptibility patterns may contribute to empiric choice of therapy.

Dosage and Administration

Description Procef (Cefprozil) Dosage and Administration is an automatic translation from the original language.
Do not use this information for any medical prescription or manipulation under any circumstances.
Be sure to read the original instructions for the medicine from the package.
This description may contain numerous errors due to automatic translation!
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Procef (Cefprozil) (cefprozil) is administered orally.

maximum 5 mg/kg q12h 10 _a SKIN STRUCTURE and SKIN _b Uncomplicated skin infections and skin structure 20 mg/kg q24h 10 Infants and children (6 months – 12 years) 900 36 TOP MEETING _b Middle ear infection (see INDICATIONS AND USAGE and CLINICAL STUDIES ) 15 mg/kg q12h 10 acute sinusitis (higher dose should be used for moderate to severe infections) 7. 5 mg/kg q12h or 15 mg / kg q12h 10 _a in the treatment of infections Streptococcus pyogenes Procef (Cefprozil) (cefprozil) should be administered for at least 10 days.
_b Do not exceed recommended adult doses.

Renal insufficiency

Cefprozil may be administered to patients with renal insufficiency. The following dosing schedule should be used.

Hepatic insufficiency

Dose adjustment is not required in patients with hepatic insufficiency.

Special warnings and precautions

Description Special Warnings and Precautions Procef (Cefprozil) is an automatic translation from the original language.
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WARning fprozil) ,(cefprozil) , CEPHALOSPORINE, PENICILLIN OR OTHER MEDICINAL PRODUCTS ARE ADMINISTERED IF THE PRODUCT PENICILLINS SHOULD BE ADMINISTRATED, THE PROPOSAL THAT KREIZEMMP’S RESPONSIBILITY IS NECESSARY IN β-LACTAM-ANTIBIOTIKA AND BIS 10% of patients allergic to penicillin may be REPRESENTED in HISTORIES. IF AN ANALLER GOVERNMENT ON PROCEF (Cefprozil) ,(cefprozil) CALL, APPLY MEDICINE. IMPACTS ON LIABILITY FROM SUSPENSION MAY REQUIRE TREATMENT WITH ADRENALINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, CONTINUOUS FLUIDS, INSUFFICIENT ANTHISTAMINS, CORTIXTEROIDS, MOVING FIREPLACES AND ATEMETHERIC CONTROLS AS CL INIC DISPLAY.

Clostridium difficile Associated diarrhea (CADD) has been reported with almost all antibacterial agents, including Procef (Cefprozil) (cefprozil), and can range from mild diarrhea to fatal colitis. Treatment with antibacterial agents alters the normal intestinal flora and leads to overgrowth of C. difficile .

C. difficile produces toxins A and B that contribute to the development of CDAD. Hypertoxin producing strains C. difficile causes increased morbidity and mortality because these infections may be resistant to antimicrobial therapy and may require colectomy. CDAD should be considered in all patients who have diarrhea after antibiotic use. A careful medical history is required as CDAD has been reported to occur two months after antibiotic administration.

If CDAD is suspected or confirmed, continued use of antibiotics that is not against C. difficile sent, subject to cancellation. Adequate fluid and electrolyte management, protein supplementation, antibiotic treatment C. difficile , and surgical evaluation should be initiated clinically.

PRECAUTIONS

general

Prescription Procef (Cefprozil) (cefprozil) in the absence of a proven or strongly suspected bacterial infection or prophylactic indication is unlikely to benefit the patient and increase the risk of developing drug-resistant bacteria.

In patients with known or suspected renal insufficiency (see DOSAGE AND ADMINISTRATION ), close clinical observation and appropriate laboratory tests should be performed before and during therapy. The total daily dose of Procef (Cefprozil) (cefprozil) should be reduced in these patients, as these individuals may experience high and/or prolonged plasma antibiotic concentrations compared to usual doses. Cephalosporins, including Procef (Cefprozil) (cefprozil), should be used with caution in patients receiving strong diuretics, as they are suspected of affecting renal function.

Procef (Cefprozil) (cefprozil) may lead to overgrown non-susceptible organisms. Careful monitoring of the patient is essential. If superinfection occurs during therapy, appropriate measures should be taken.

Cefprozil should be used with caution in people with a history of gastrointestinal disease, especially colitis.

Positive direct ear tests have been reported during treatment with cephalosporin antibiotics.

Carcinogenesis, mutagenesis and impaired fertility

Long-term in vivo – No studies have been conducted to evaluate the carcinogenic potential of cefprozil.

Cefprozil was not in Ames Salmonella – or E. coli WP2 urvA reversion assays are still detected as mutagens in the HGPRT direct gene mutation assay of Chinese Hamster Ovary cells and do not cause chromosomal abnormalities in Chinese Hamster Ovary cells cell or unscheduled DNA synthesis in in rat hepatocytes in vitro Chromosomal aberrations were found in bone marrow cells in rats that were oral, with more than 30 times the recommended human dose as a function of mg/m. ₂ were not met.

Fertility was impaired in male or female rats treated with oral doses of cefprozil 18.5 times the highest recommended human dose based on mg/m ₂ was not observed.

Pregnancy

Teratogenic effects: pregnancy category B

Reproduction studies have been performed in rabbits, mice and rats with oral doses of cefprozil at 0.8, 8.5 and 18.5 times the maximum human daily dose (1000 mg) per mg/m ₂ is carried out and does not harm the fetus. However, there are no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should only be used during pregnancy if clearly needed.

Work and Delivery

Cefprozil has not been studied for use during childbirth. Treatment should only be carried out if clearly needed.

Nursing mothers

Small amounts of cefprozil (<0.3% of dose) have been found in breast milk following a single 1 g dose in women who are breastfeeding. Mean values ​​over 24 hours ranged from 0.25 to 3.3 µg/mL. Caution should be exercised when administering Procef (Cefprozil) (cefprozil) to a nursing woman, as the effect of cefprozil on nursing infants is unknown.

Pediatric use

(See INDICATIONS AND USAGE and DOSAGE AND ADMINISTRATION .)

The safety and efficacy of cefprozil in the treatment of otitis media was determined in the age groups 6 months to 12 years. The use of Procef (Cefprozil) (cefprozil) for the treatment of otitis media is supported by evidence from adequate and well-controlled studies of cefprozil in pediatric patients. (See CLINICAL STUDIES. )

The safety and efficacy of cefprozil in the treatment of pharyngitis/tonsillitis or uncomplicated infections of the skin and skin structure was determined in the age groups of 2 to 12 years. The use of Procef (Cefprozil) (cefprozil) for the treatment of these infections is supported by evidence from adequate and well-controlled studies of cefprozil in pediatric patients.

The safety and efficacy of cefprozil in the treatment of acute sinusitis was determined in the age groups 6 months to 12 years. The use of Procef (Cefprozil) (cefprozil) in these age groups is supported by data from adequate and well-controlled studies of cefprozil in adults.

Safety and efficacy in pediatric patients under 6 months of age have not been demonstrated for the treatment of otitis media or acute sinusitis or under 2 years of age for the treatment of pharyngitis/tonsillitis or uncomplicated infections of the skin and skin structure. However, accumulation of other cephalosporin antibiotics has been reported in neonates (as a result of the drug’s long half-life in this age group).

Geriatric Use

Of more than 4,500 adults who received Procef (Cefprozil) (cefprozil) in clinical trials, 14% were 65 years of age or older, while 5% were 75 years of age or older. When geriatric patients received the usual recommended adult doses, their clinical efficacy and safety were comparable to those in non-geriatric adult patients. Other reported clinical experiences have not found differences in response between older and younger patients, but a greater sensitivity of some older people to the effects of Procef (Cefprozil) cannot be ruled out (see CLINICAL PHARMACOLOGY ).

Procef (cefprozil) (cefprozil) is known to be excreted primarily via the kidney and the risk of toxic reactions to this drug may be higher in patients with renal insufficiency. Because elderly patients are more likely to have reduced renal function, care should be taken in dose selection and this may be useful in monitoring renal function. Please refer to DOSAGE AND ADMINISTRATION for dosage recommendations for patients with renal insufficiency.

Side effects

Description Side effects Procef (Cefprozil) is an automatic translation from the original language.
Do not use this information for any medical prescription or manipulation under any circumstances.
Be sure to read the original instructions for the medicine from the package.
This description may contain numerous errors due to automatic translation!
Keep this in mind and do not use this description!

more…

Side effects of cefprozil are similar to those seen with other oral cephalosporins. Cefprozil has generally been well tolerated in controlled clinical trials. Approximately 2% of patients discontinued cefprozil therapy due to adverse events.

The most common side effects observed in patients treated with cefprozil are:

Gastrointestinal tract: Diarrhea (2.9%), nausea (3.5%), vomiting (1%) and abdominal pain ( 1%).

Hepatobiliary: increased values ​​of AST (SGOT) (2%), ALT (SGPT) (2%), alkaline phosphatase (0.2%) and bilirubin (<0.1%). As with some penicillins and some other cephalosporin antibiotics, cholestatic jaundice has rarely been reported.

Hypersensitivity: Rash (0.9%), urticaria (0.1%). These reactions have been reported more frequently in children than in adults. Signs and symptoms usually appear a few days after the start of therapy and subside within a few days after the end of therapy.

CNS: Dizziness (1%), hyperactivity, headache, nervousness, insomnia, confusion and somnolence have been reported rarely (<1%). All were reversible.

Hematopoietic: Decreased white blood cell count (0.2%), eosinophilia (2.3%).

Kidney: Elevated serum creatinine (0.1%), serum creatinine (0.1%).

Other: Wind deflection and superinfection (1.5%), genital itching and vaginitis (1.6%).

The following side effects, regardless of a proven causal relationship with Procef (Cefprozil) (cefprozil), are rarely reported during post-marketing surveillance: anaphylaxis, angioedema, colitis (including pseudomembranous colitis), erythema multiforme, fever, serum reactions, Stevens -Johnson-.

Sales of cephalosporin class

In addition to the side effects listed above that have been observed in patients treated with cefprozil, the following side effects and altered laboratory tests for cephalosporin class 9 antibiotics have been reported0003

Aplastic anemia, hemolytic anemia, bleeding, renal dysfunction, toxic epidermal necrolysis, toxic nephropathy, prolonged prothrombin time, positive forge test, LDH elevation, pancytopenia, neutropenia, agranulocytosis.

Several cephalosporins have been implicated in convulsions, especially in patients with renal insufficiency, unless the dose was reduced. (See DOSAGE AND ADMINISTRATION and TRANSLATION ) If convulsions occur in connection with drug therapy, the drug should be discontinued. Anticonvulsant therapy may be given if clinically indicated.

Procef (Cefprozil) price

We do not have exact data on the cost of the drug.
However, we will provide data for each active ingredient

The average cost of Cefprozil 500 mg per unit in online pharmacies is from 2$ to 3.