What are the common side effects of Desyrel (trazodone)? How can they be managed? Discover the key information you need to know about this antidepressant medication.

Understanding Desyrel (Trazodone): An Overview

Desyrel, the brand name for the medication trazodone, is an antidepressant drug commonly prescribed to treat depression and other mental health conditions. It works by helping to restore the balance of a natural chemical in the brain called serotonin, which can impact mood, appetite, and energy levels. Trazodone is typically taken orally, either once or twice a day, and can be taken with or without food.

Potential Side Effects of Desyrel (Trazodone)

Like any medication, Desyrel can cause a variety of side effects. Some of the more common side effects associated with trazodone include:

• Nausea, vomiting, and diarrhea
• Drowsiness and dizziness
• Tiredness and fatigue
• Blurred vision
• Changes in weight, both gain and loss
• Headache and muscle aches/pains
• Dry mouth and bad taste in the mouth
• Stuffy nose and constipation
• Changes in sexual interest or ability

It’s important to note that not everyone who takes Desyrel will experience these side effects, and the severity can vary from person to person. If any of these side effects persist or worsen, it’s crucial to inform your healthcare provider.

Managing Desyrel Side Effects

If you experience side effects while taking Desyrel, there are a few things you can do to help manage them:

1. Dry mouth: Suck on sugarless hard candy or ice chips, chew sugarless gum, drink water, or use a saliva substitute.
2. Dizziness and lightheadedness: Get up slowly when rising from a sitting or lying position.
3. Nausea and vomiting: Try taking the medication with food or a snack.
4. Drowsiness: If this is a problem, try taking the medication at bedtime.

Remember, it’s essential to follow your healthcare provider’s instructions and not make any changes to your medication regimen without their guidance.

Rare and Serious Side Effects of Desyrel

While the majority of Desyrel side effects are relatively mild, there are a few more serious side effects that can occur, although they are less common. These include:

• Suicidal thoughts or behavior
• Unusual behavior changes
• Worsening depression or other mental health symptoms
• New or worsening anxiety, panic attacks, or trouble sleeping
• Irritability, hostility, impulsive actions, or severe restlessness
• Very rapid speech

If you experience any of these more serious side effects, it’s crucial to contact your healthcare provider immediately.

Dosage and Administration Considerations

The dosage of Desyrel is based on your individual medical condition and response to treatment. Your healthcare provider may start you on a low dose and gradually increase it to reduce the risk of side effects. It’s important to take Desyrel exactly as prescribed, without increasing the dose or frequency on your own. Suddenly stopping Desyrel can also lead to withdrawal symptoms, so it’s crucial to work with your healthcare provider if you need to discontinue the medication.

Factors that May Influence Desyrel Side Effects

Several factors can influence the likelihood and severity of Desyrel side effects, including:

• Age: Younger individuals, especially those under 25, may be at a higher risk of experiencing certain side effects, such as worsening depression or suicidal thoughts.
• Underlying medical conditions: Existing health problems may interact with Desyrel and increase the risk of side effects.
• Dosage and frequency: Higher doses or more frequent administration of Desyrel may lead to a greater risk of side effects.
• Timing of administration: Taking Desyrel at bedtime may help alleviate drowsiness, while taking it with food may reduce gastrointestinal side effects.

Importance of Monitoring and Reporting Side Effects

It’s crucial to monitor for any side effects while taking Desyrel and report them to your healthcare provider promptly. This allows your provider to make informed decisions about your treatment, such as adjusting the dosage or switching to a different medication if necessary. Regular communication with your healthcare team is essential for ensuring the safe and effective use of Desyrel.

Desyrel Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Warnings:

Antidepressant medications are used to treat a variety of conditions, including depression and other mental/mood disorders. These medications can help prevent suicidal thoughts/attempts and provide other important benefits. However, studies have shown that a small number of people (especially people younger than 25) who take antidepressants for any condition may experience worsening depression, other mental/mood symptoms, or suicidal thoughts/attempts. It is very important to talk with the doctor about the risks and benefits of antidepressant medication (especially for people younger than 25), even if treatment is not for a mental/mood condition.

Tell the doctor right away if you notice worsening depression/other psychiatric conditions, unusual behavior changes (including possible suicidal thoughts/attempts), or other mental/mood changes (including new/worsening anxiety, panic attacks, trouble sleeping, irritability, hostile/angry feelings, impulsive actions, severe restlessness, very rapid speech). Be especially watchful for these symptoms when a new antidepressant is started or when the dose is changed.

Warnings:

Antidepressant medications are used to treat a variety of conditions, including depression and other mental/mood disorders. These medications can help prevent suicidal thoughts/attempts and provide other important benefits. However, studies have shown that a small number of people (especially people younger than 25) who take antidepressants for any condition may experience worsening depression, other mental/mood symptoms, or suicidal thoughts/attempts. It is very important to talk with the doctor about the risks and benefits of antidepressant medication (especially for people younger than 25), even if treatment is not for a mental/mood condition.

Tell the doctor right away if you notice worsening depression/other psychiatric conditions, unusual behavior changes (including possible suicidal thoughts/attempts), or other mental/mood changes (including new/worsening anxiety, panic attacks, trouble sleeping, irritability, hostile/angry feelings, impulsive actions, severe restlessness, very rapid speech). Be especially watchful for these symptoms when a new antidepressant is started or when the dose is changed.

… Show More

Uses

This medication is used to treat depression. It may help to improve your mood, appetite, and energy level as well as decrease anxiety and insomnia related to depression. Trazodone works by helping to restore the balance of a certain natural chemical (serotonin) in the brain.

How to use Desyrel Tablet

Read the Medication Guide provided by your pharmacist before you start using trazodone and each time you get a refill. If you have any questions, consult your doctor or pharmacist.

Take this medication by mouth after a meal or snack as directed by your doctor, usually once or twice daily. If drowsiness is a problem and you are taking 1 dose daily, take it at bedtime. If you are taking 2 doses each day, it may help to take 1 of the doses at bedtime. Follow your doctor’s directions carefully.

Dosage is based on your medical condition and response to treatment. To reduce your risk of side effects, your doctor may start you at a low dose and gradually increase your dose.

Take this medication exactly as prescribed. Do not increase your dose or take this medication more often than prescribed. Your condition will not improve any faster, and the risk of serious side effects may be increased.

Keep taking this medication as prescribed even if you feel well. To help you remember, take it at the same time(s) each day. Do not stop taking this medication without consulting your doctor. Anxiety, agitation, and trouble sleeping can occur if the drug is suddenly stopped.

It may take 2 to 4 weeks before you notice the full effects of this medication. Tell your doctor if your condition lasts or gets worse.

Side Effects

See also the Warning section.

Nausea, vomiting, diarrhea, drowsiness, dizziness, tiredness, blurred vision, changes in weight, headache, muscle ache/pain, dry mouth, bad taste in the mouth, stuffy nose, constipation, or change in sexual interest/ability may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

To relieve dry mouth, suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or use a saliva substitute.

To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: shaking (tremors), nightmares, ringing in the ears, problems urinating, blood in urine, signs of infection (such as such as sore throat that doesn’t go away, fever), shortness of breath, stomach/abdominal pain.

Get medical help right away if you have any very serious side effects, including: chest/jaw/left arm pain, fainting, fast/irregular heartbeat, seizures, eye pain/swelling/redness, widened pupils, vision changes (such as seeing rainbows around lights at night).

This medication may increase serotonin and rarely cause a very serious condition called serotonin syndrome/toxicity. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take (see Drug Interactions section). Get medical help right away if you develop some of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, unusual agitation/restlessness.

Rarely, males may have a painful or prolonged erection lasting 4 or more hours. If this occurs, stop using this drug and get medical help right away, or permanent problems could occur.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking trazodone, tell your doctor or pharmacist if you are allergic to it; or to nefazodone; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: personal or family history of bipolar disorder, personal or family history of suicide attempts, heart disease (such as irregular heartbeat, heart attack), liver disease, kidney disease, blood pressure problems, personal or family history of glaucoma (angle-closure type).

This drug may make you dizzy or drowsy or blur your vision. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).

Trazodone may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.

The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using trazodone, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).

Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/”water pills”) or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using trazodone safely.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Older adults may be more sensitive to the side effects of this drug, especially drowsiness, dizziness, and QT prolongation (see above).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

Since untreated mental/mood problems (such as depression) can be a serious condition, do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy.

This medication passes into breast milk. Consult your doctor before breast-feeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

A product that may interact with this drug is: digoxin.

Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before and after treatment with this medication. Ask your doctor when to start or stop taking this medication.

Other medications can affect the removal of trazodone from your body, which may affect how trazodone works. Examples include azole antifungals (such as itraconazole, ketoconazole), HIV protease inhibitors (such as indinavir), macrolide antibiotics (such as erythromycin), ritonavir, drugs used to treat seizures (such as phenytoin), among others.

The risk of serotonin syndrome/toxicity increases if you are also taking other drugs that increase serotonin. Examples include street drugs such as MDMA/”ecstasy,” St. John’s wort, certain antidepressants (including SSRIs such as fluoxetine/paroxetine, SNRIs such as duloxetine/venlafaxine), among others. The risk of serotonin syndrome/toxicity may be more likely when you start or increase the dose of these drugs.

Tell your doctor or pharmacist if you are taking other products that cause drowsiness including alcohol, marijuana (cannabis), antihistamines (such as cetirizine, diphenhydramine), drugs for sleep or anxiety (such as alprazolam, diazepam, zolpidem), muscle relaxants, and opioid pain relievers (such as codeine).

Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

Does Desyrel Tablet interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: painful/prolonged erection, slow/rapid/irregular heartbeat, unusual drowsiness, unusual dizziness, vomiting, trouble breathing, seizures.

Do not share this medication with others.

Lab and/or medical tests should be done while you are taking this medication. Keep all medical and lab appointments. Consult your doctor for more details.

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Images

Next

Save up to 80% on your prescriptions.

Available coupons

Save up to 80% on your prescription with WebMDRx

Drug Survey

Are you currently using Desyrel Tablet?

This survey is being conducted by the WebMD marketing sciences department.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

Desyrel

Drug Class: Antidepressant, Miscellaneous

Table of Contents

• Overview
• How to Take It
• Side Effects
• Warnings & Precautions
• Drug Interactions
• Dosage & Missing a Dose
• Storage
• Pregnancy or Nursing
• More Information

Overview

Desyrel (trazodone) is used to treat all types of depression. It belongs to the SARI (serotonin antagonist and reuptake inhibitor) class. It is also used to treat anxiety and insomnia related to depression. Your doctor may use this medicine to treat other conditions.

This medicine helps relieve depression by increasing the amount of a chemical called serotonin in the brain centers.

This information is for educational purposes only. Not every known side effect, adverse effect, or drug interaction is in this database. If you have questions about your medicines, talk to your health care provider.

How to Take It

This medicine should be taken with food and the tablet can be crushed. If it causes excessive drowsiness or dizziness the larger portion of it should be taken at bedtime and the rest should be divided into two or three doses for the daily usage.

Side Effects

Side effects that may occur while taking this medicine include:

• changes in weight, weight gain
• dry mouth
• constipation
• drowsiness
• confusion
• lightheadedness

Contact your doctor immediately if you experience:

• tremors or shaking
• sore throat
• trouble breathing
• seizures
• irregular or fast heartbeat
• ringing in the ears
• eye swelling or pain
• blood in urine/problems urinating
• nightmares
• fever
• fainting

Warnings & Precautions

• Talk to your doctor before you take this medicine if you have a history of heart disease, epilepsy, alcoholism, liver or kidney disease, or if you are having general anesthesia.
• DO NOT use trazodone if you are allergic to it or if you are being treated with methylene blue injections.
• Alcohol can add to the side effects of this medicine and should be avoided.
• This medicine causes dizziness or drowsiness. DO NOT drive, and restrict activities until you know how this medicine will affect you.
• DO NOT use trazodone if in the past 2 weeks you have taken an MAO inhibitor.
• A rare side effect causing a prolonged painful erection in males (priaprism) has occurred. If you experience this, stop taking the drug and contact your healthcare provider immediately.
• For an overdose, seek medical attention immediately. For non emergencies, contact your local or regional poison control center at 1-800-222-1222.

Drug Interactions

This medicine may increase the affects antihypertensive drugs, drugs with sedative effects, phenytoin (Dilantin) or fosphenytoin (Celebyx) and tramadol (Ultram).

Dosage & Missed Dose

Trazodone is available as an extended-release or regular release oral tablet. The tablets should not be chewed or crushed. They may be broken in half, depending on dose prescribed by your doctor.

Take regular tablets with food 2 or more times / day.

Take extended-release tablets, once / day at bedtime on an empty stomach.

If you miss a dose, take your next dose as soon as you remember. If it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not double doses or take extra medicine to make up for the missed dose.

Storage

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (preferably not in the bathroom). Throw away any medication that is outdated or no longer needed.

Pregnancy/Nursing

Lung problems or other complications in the baby may arise if you are taking this medication while pregnant. There is risk of depression relapse if you stop taking your antidepressant. Tell your doctor right away if you become pregnant while taking Trazodone. Do not start or stop taking this medicine during pregnancy without consulting your doctor.

More Information

For more information, talk to your doctor, pharmacist or health care provider, or you can visit this website, https://www.nlm.nih.gov/medlineplus/druginfo/meds/a681038.html for additional information from the manufacturer of this drug.

instructions for use, dosage, composition, analogues, side effects / Pillintrip

Page reviewed by pharmacist Kovalenko Svetlana Olegovna Last update 1969-12-31

Top 20 medicines with the same ingredients: original language.
Do not use this information for any medical prescription or manipulation under any circumstances.
Be sure to read the original instructions for the medicine from the package.

This description may contain numerous errors due to automatic translation!
Keep this in mind and do not use this description!

more…

Desirel

Therapeutic indications

Description Therapeutic indications Desirel is an automatic translation from the original language.
Do not use this information for any medical prescription or manipulation under any circumstances.
Be sure to read the original instructions for the medicine from the package.
This description may contain numerous errors due to automatic translation!
Keep this in mind and do not use this description!

more…

Indication is a term used for a list of conditions or symptoms or diseases for which a patient prescribes or uses a drug. For example, acetaminophen or paracetamol is used by a patient for a fever, or a doctor prescribes it for a headache or body pain. Currently, fever, headache and body pain are indications for paracetamol. The patient should be aware of the indications of drugs that are used for common diseases, as they can be taken by a doctor without a prescription from a pharmacy or without a prescription.

Desirel is indicated for the treatment of depression. Desirel (Desirel) has been shown to be effective in both inpatient and outpatient settings, as well as for depressed patients with and without celebrities. The depressive illness of the examined patients met the main criteria for depressive episodes of the Diagnostic and Statistical Manual of the American Psychiatric Association, III.

A major depressive episode involves a marked and relatively persistent (nearly every day for at least two weeks) depressive or dysphoric mood that usually affects daily function and includes at least four of the following eight symptoms: change in appetite, change in sleep , Psychomotor agitation or delay, Loss of interest in normal activities or decreased libido, increased fatigue, Feelings of guilt or worthlessness, thinking slower or impaired concentration, and suicidal thoughts or attempts.

Desirel (Desirel) is an antidepressant. It affects chemicals in the brain that can get out of balance in people with depression.

Desirel is used to treat major depressive disorder (MDD).

Desirel may also be used for purposes not listed in this medication guide.

Dosage and Administration

Description Dosage and Administration Desirel is an automatic translation from the original language.
Do not use this information for any medical prescription or manipulation under any circumstances.
Be sure to read the original instructions for the medicine from the package.
This description may contain numerous errors due to automatic translation!
Keep this in mind and do not use this description!

more…

Dose selection

The recommended starting dose of Desirel is 150 mg once daily in adults. The dose may be increased by 75 mg/day every three days (ie, start 225 mg on day 4 of therapy). The maximum daily dose should not exceed 375 mg.

• Desirl tablets should be taken by mouth at the same time each day, in the late evening, preferably at bedtime, on an empty stomach.
• Once an adequate response has been achieved, the dosage may be gradually reduced with subsequent adjustment depending on the therapeutic response.
• Patients should be screened for withdrawal symptoms when Desirel treatment is discontinued. If possible, the dose should be gradually reduced.

Maintenance treatment

The effectiveness of Desirel for maintenance treatment of MDD has not been evaluated. Although there is no evidence to answer the question of how long a patient treated with Desyrel should continue taking the drug, it is generally recommended to continue treatment for several months after the initial response. Patients should be maintained at the lowest effective dose and re-evaluated regularly to determine continued need for maintenance treatment.

Patient switching to or from a monoamine oxidase inhibitor (MAOI) For psychiatric treatment

At least 14 days must elapse between discontinuation of an MAOI for psychiatric treatment and initiation of therapy with Desirel. Conversely, at least 14 days after stopping Desirel before starting an MAOI for the treatment of psychiatric disorders should be allowed.

Using Desirel with other Maori such as Linezolid or Methylene Blue

Do not start Desirel in a patient receiving linezolid or intravenous methylene blue because there is an increased risk of serotonin syndrome. Other procedures, including hospitalization, should be considered in a patient who requires more urgent treatment for a psychiatric condition.

In some cases, a patient already on Desirel therapy may require urgent treatment with linezolid or intravenous methylene blue. If there are no acceptable alternatives to treatment with linezolid or intravenous methylene blue, and the potential benefits of treatment with linezolid or intravenous methylene blue outweigh the risks of serotonin syndrome in an individual patient, Desirel should be discontinued immediately and linezolid or intravenous methylene blue may be administered. The patient should be monitored for symptoms of serotonin syndrome two weeks or up to 24 hours after the last dose of linezolid or intravenous methylene blue, whichever comes first. Desirel therapy may be restarted 24 hours after the last dose of linezolid or intravenous methylene blue.

The risk of administering methylene blue when administered non-intravenously because (eg. oral tablets or local injections) or at intravenous doses that are much lower than 1 mg/kg with Desirel is unclear. However, the clinician should be aware of the potential for symptoms of serotonin syndrome with this use (see WARNINGS AND PRECAUTIONS ).

important instructions for administration

Desirel tablets are designed to provide dosing flexibility.

Desirel may be swallowed whole or administered as half a tablet by breaking the tablet along the finish line. The coating of the tablet does not affect the properties of the controlled release tablet.

To maintain its controlled release properties, Desirel should not be chewed or crushed.

How Delive

Dosage of the forms and strengths of

Desirel tablets are available in the following strengths:

• Desirel Palts, 150 mg of Desirel (yellowish-beige capsule form covered on both sides and printed using it. DDS 080)
• Desirel tablets containing halibut with 300 mg Desirel (beige orange capsule-shaped tablet, coated on both sides and printed with DDS 081)

Storage and handling

Desirel 150 mg yellowish beige tablet shaped capsules coated on both sides and printed with DDS 080. Supplied as follows:

Bottles of 30 tablets NDR 43595-080-03

capsules coated on both sides and printed DDS 081. Supplied as follows:

Bottles of 30 tablets NDR 43595-081-03

Store at room temperature (15 – 30°C) in tight, light-resistant containers.

Angelini Pharma Inc. Gaithersburg, MD 20877 Revised: July 2014

Contraindications

Description Contraindications Desirel is an automatic translation from the original language.
Do not use this information for any medical prescription or manipulation under any circumstances.
Be sure to read the original instructions for the medicine from the package.
This description may contain numerous errors due to automatic translation!
Keep this in mind and do not use this description!

more…

See also:
What is the most important information I should know about Desirel?

Before taking Desirel, tell your doctor if you have bipolar disorder (manic depression), heart disease or “long QT syndrome”, liver or kidney disease, a history of drug abuse or suicidal thoughts, or have recently had a heart attack .

You may have suicidal thoughts when you first take an antidepressant, especially when you are younger than 24 years of age. Your doctor should check on you for regular visits for at least the first 12 weeks of treatment.

Call your doctor right away if you develop new or worsening symptoms, eg. mood or behavior changes, anxiety, panic attacks, sleep disturbances, or if you are impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), feeling more depressed, or having suicidal thoughts or hurting yourself.

do not drink alcohol. Desirel may increase the effects of alcohol, which can be dangerous.

Desirel can make you think or influence your reactions. Be careful when driving or doing something in which you need to be vigilant.

Stop taking Desirel and call your doctor right away if you have a penile erection that is painful or lasts 6 hours or longer. This is a medical emergency that can lead to a serious condition that needs to be corrected with surgery.

Special warnings and precautions

Description Special Warnings and Precautions Desirel is an automatic translation from the original language.
Do not use this information for any medical prescription or manipulation under any circumstances.
Be sure to read the original instructions for the medicine from the package.
This description may contain numerous errors due to automatic translation!
Keep this in mind and do not use this description!

more…

Use Desirel extended-release tablets as directed by your doctor. Check the medication label for detailed dosage instructions.

• Desirel extended-release tablets come with an additional patient information sheet called the Medication Guide. Read it carefully. Read this again every time you receive Desirel Extended release tablets.
• Take Desirel extended-release tablets by mouth on an empty stomach at least 1 hour before or 2 hours after a meal.
• Take Desirel extended-release tablets at bedtime unless your doctor tells you otherwise.
• Swallow Desirel extended release tablets in general. Do not crush or chew before swallowing. If your doctor tells you to halve your Desirel extended release tablets, be sure to break the tablet along the finish line.
• Desirel Extended Release Tablets are best when taken at the same time each day.
• continue taking Desirel extended release tablets even if you feel comfortable. Don’t miss the banks.
• Do not stop taking Desirel extended release tablets. Side effects such as restlessness, restlessness, or sleep disturbances may occur. If you need to stop taking Desirel extended-release tablets or add a new medicine, your doctor will gradually decrease your dose.
• If you miss taking Desirel extended-release tablets, take them as soon as possible. When it’s time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at a time.

Ask your doctor about using Desirel extended-release tablets.

there are specific and general uses for a drug or drug. The drug can be used to prevent a disease, treat a disease for a period of time, or treat a disease. It can also be used to treat a specific symptom of a disease. The use of drugs depends on the form in which the patient takes. It may be more useful in the form of an injection or sometimes in the form of a tablet. The drug may be used for a single alarm symptom or life-threatening condition. Although some medicines may be stopped after a few days, some medicines must be continued for a longer period of time to benefit from them.

Use: tagged ads

Major depression (unipolar): Treatment of unipolar depressive disorder

Off label Used

Aggressive or agitated behavior associated with dementia

Limited data of studied patients indicate that Desirel may be useful in patients with aggression or agitation associated with dementia, if the frequency and severity of symptoms and the use of additional medications are reduced.

The American Academy of Sleep Medicine’s guidelines for the treatment of chronic insomnia suggest that Desirl should not be used for sleep disorders or sleep disorders due to insufficient evidence.

Interaction with other drugs

Description Interaction with other drugs Desirel is an automatic translation from the original language.
Do not use this information for any medical prescription or manipulation under any circumstances.
Be sure to read the original instructions for the medicine from the package.
This description may contain numerous errors due to automatic translation!
Keep this in mind and do not use this description!

more…

See also:
What other drugs affect Desyrel?

Monoamine oxidase inhibitor (MAOI)

Serotonergics

Central nervous system (CNS) depressants

Desirel may increase the response to alcohol, barbiturates and other CNS depressants.

Cytochrome P450-3A4 inhibitors

In vitro drug metabolism studies indicate that there is a potential for drug interactions when administered with Desirel with inhibitors of cytochrome P450 3A4 (CYP3A4). The effect of short-term administration of ritonavir (200 mg twice daily, 4 doses) on the pharmacokinetics of a single dose of Desirel (50 mg) was studied in 10 healthy volunteers. Cmax Desirel increased by 34%, AUC increased by 2.4 times, half-life increased by 2.2 times, and the gap was reduced by 52%. Side effects such as nausea, hypotension and syncope have been observed with concomitant administration of ritonavir and desirel. It is likely that ketoconazole, indinavir, and other CYP3A4 inhibitors such as itraconazole may lead to a significant increase in the desired plasma concentration, with the possibility of side effects. When using Desirel with a potent CYP3A4 inhibitor, the risk of irregular heartbeat may be increased and a lower dose of Desirl may be considered.

Cytochrome P450 inducers (eg., Carbamazepine)

Carbamazepine induces CYP3A4. Following co-administration of carbamazepine 400 mg daily with Desirel 100 to 300 mg daily, carbamazepine reduced plasma concentrations of Desirel and chlorphenlipiperazine (active metabolite) by 76% and. Patients should be closely monitored to determine if an increased dose of Desirel is required while taking both drugs.

Digoxin and phenytoin

Elevated serum levels of digoxin or phenytoin have been reported in patients treated with Desirl concomitantly with one of these drugs. Monitor serum levels and adjust doses as needed.

NSAIDs, aspirin, or other drugs that affect clotting or bleeding

Due to the possible relationship between serotonin-modulating drugs and gastrointestinal bleeding, patients should be monitored and warned of the potential risk of bleeding associated with concomitant use of Desirel and an NSAID , aspirin, or other medicines that affect coagulation or bleeding.

Warfarin

There have been reports of a change (increase or decrease) in prothrombin times with warfarin and Desirel.

Drug Abuse and Dependence

Controlled substance

Desirel is not a controlled substance.

Abuse

Although Desirel has not been systematically studied for its potential for abuse in preclinical or clinical studies, no signs of addiction behavior have been found in clinical studies with Desirel. However, it is difficult to predict the extent of abuse, withdrawal, and abuse of an active CNS drug. As a result, clinicians should take a careful history of drug abuse and monitor these patients closely and watch for signs of abuse or abuse of Desirel (eg, development of tolerance, dose increase, addiction behavior).

Side effects

Description Side effects Desirel is an automatic translation from the original language.
Do not use this information for any medical prescription or manipulation under any circumstances.
Be sure to read the original instructions for the medicine from the package.
This description may contain numerous errors due to automatic translation!
Keep this in mind and do not use this description!

more…

See also:
What are the possible side effects of Desirel?

Refers to Desirel: oral tablet, extended release oral tablet

In addition to the desired effects, some unwanted effects may be caused by Desirel (the active ingredient contained in Desirel). If you experience one of these side effects, you may need medical attention.

Main side effects

You should check with your doctor immediately if any of these side effects occur while taking Desirel:

Maximum

Some of the side effects Desirel may experience may not require medical attention. If your body adjusts to the medication during treatment, these side effects may go away. Your doctor can also tell you how to reduce or prevent some of these side effects. If any of the following side effects persist, are damaging, or have any questions, contact your doctor

more common:

• dry mouth (usually mild)
• muscle or bone pain
• sleep disorders
• memory problems
• bad taste 9005 4

Less common:

• Constipation
• constant ringing or buzzing or other unexplained sound in the ears
• Diarrhea
• Hearing loss
• Muscle pain or pain
• Weight loss

Composition

Description Composition Desirel is an automatic translation from the original language.
Do not use this information for any medical prescription or manipulation under any circumstances.
Be sure to read the original instructions for the medicine from the package.
This description may contain numerous errors due to automatic translation!
Keep this in mind and do not use this description!

more.