How do suppositories work. What are the different types of suppositories. How long does it take for suppositories to start working. How to use suppositories correctly. What are common side effects of suppositories.

Understanding Suppositories: Types and Uses

Suppositories are solid medications designed to enter the body through specific openings – the rectum, vagina, or urethra. They serve as an alternative method of drug delivery when oral administration is not feasible or effective. These small, often cone-shaped or oval medications are encased in substances like cocoa butter or gelatin, which melt at body temperature to release the active ingredients.

There are three main types of suppositories:

• Rectal suppositories: Inserted into the rectum or anus
• Vaginal suppositories: Placed in the vagina
• Urethral suppositories: Used in the urethra (primarily for men)

Each type serves different medical purposes and requires specific administration techniques.

Why Are Suppositories Used?

Healthcare providers may recommend suppositories in various scenarios:

• When patients are unable to swallow oral medications
• During episodes of vomiting or nausea
• To bypass digestive system issues that might interfere with drug absorption
• For medications with unpleasant tastes
• To deliver drugs that would be destroyed by stomach acid
• To treat local conditions in the rectum or vagina

Research indicates that rectal drug administration provides a relatively stable environment for medication delivery, although absorption rates may be slower compared to oral routes.

The Science Behind Suppository Action

Understanding how suppositories work involves delving into the physiological processes that occur once the medication is inserted. The effectiveness of a suppository depends on several factors:

Melting Point and Body Temperature

Most suppositories are designed to melt at body temperature (around 37°C or 98.6°F). As the suppository base melts, it releases the active drug into the surrounding tissues. This process is crucial for the medication to take effect.

Absorption Mechanisms

Depending on the type of suppository, absorption occurs through different routes:

• Rectal suppositories: Absorbed through the rectal mucosa into the bloodstream
• Vaginal suppositories: Absorbed locally or through vaginal tissue into systemic circulation
• Urethral suppositories: Absorbed through the urethral lining

The rich blood supply in these areas facilitates drug absorption and distribution throughout the body.

First-Pass Metabolism Avoidance

One significant advantage of suppositories is their ability to bypass the first-pass metabolism in the liver. This process can significantly reduce the potency of orally administered drugs. By avoiding this step, suppositories often require lower doses to achieve the same therapeutic effect as oral medications.

Time Frame: How Long Do Suppositories Take to Work?

The onset of action for suppositories can vary depending on several factors:

Rectal Suppositories

Rectal suppositories typically begin to work within 15 to 60 minutes after insertion. However, this can vary based on the specific medication and the individual’s physiology. For instance:

• Laxative suppositories may produce a bowel movement within 15-60 minutes
• Pain relief suppositories might take 30-60 minutes to provide noticeable effects
• Fever-reducing suppositories could start working within 30-45 minutes

Vaginal Suppositories

The timeframe for vaginal suppositories to take effect can range from a few hours to several days, depending on the condition being treated:

• Antifungal suppositories may show improvement in symptoms within 1-3 days
• Hormonal suppositories for vaginal dryness might take several days to weeks for full effect
• Antibacterial suppositories could start combating infections within 24-48 hours

Urethral Suppositories

Urethral suppositories, primarily used for erectile dysfunction, typically start working within 5-10 minutes of insertion. However, individual responses may vary.

Proper Administration Techniques for Optimal Results

To ensure suppositories work effectively and within the expected timeframe, proper administration is crucial. Here’s a step-by-step guide for rectal suppositories, which are the most common type:

1. Wash hands thoroughly with soap and warm water
2. Remove the suppository from its packaging
3. If necessary, moisten the suppository with water or a water-based lubricant
4. Choose a comfortable position (lying on side or standing with one foot elevated)
5. Gently insert the suppository into the rectum, narrow end first, about 1 inch for adults
6. Hold the buttocks together for a few moments to prevent expulsion
7. Remain in position for about 15 minutes if possible
8. Wash hands again after insertion

For vaginal suppositories, the process is similar, but they are typically inserted while lying on the back with knees bent. Urethral suppositories require careful insertion into the urethra and should only be used under medical supervision.

Factors Influencing Suppository Efficacy

Several factors can affect how quickly and effectively suppositories work:

Rectal Contents

The presence of stool in the rectum can interfere with suppository absorption. It’s often recommended to try to have a bowel movement before inserting a rectal suppository.

Body Position

Maintaining a position that keeps the suppository in place (such as lying down) for 15-30 minutes after insertion can improve absorption and efficacy.

Suppository Formulation

The base material of the suppository (e.g., cocoa butter, glycerin) can affect its melting rate and, consequently, the drug release rate.

Individual Physiology

Factors such as body temperature, local pH, and blood flow can influence how quickly the suppository melts and the drug is absorbed.

Medication Properties

The chemical properties of the drug itself, including its solubility and molecular size, play a role in absorption rates.

Potential Side Effects and Precautions

While suppositories are generally safe when used as directed, they can cause some side effects:

Common Side Effects

• Local irritation or discomfort
• Burning sensation
• Rectal bleeding (rarely)
• Diarrhea (with some laxative suppositories)

Precautions

To minimize risks and ensure effective treatment:

• Follow the prescribed dosage and administration schedule
• Do not use suppositories with signs of damage or melting
• Consult a healthcare provider if symptoms persist or worsen
• Inform your doctor of any allergies or sensitivities
• Store suppositories as directed, usually in a cool, dry place

Comparing Suppositories to Other Drug Delivery Methods

Suppositories offer unique advantages and disadvantages compared to other medication forms:

Advantages

• Bypass first-pass metabolism in the liver
• Useful for patients who can’t take oral medications
• Can provide local and systemic effects
• Often require lower doses than oral medications

Disadvantages

• May be uncomfortable or inconvenient for some patients
• Absorption can be inconsistent
• Limited drug options compared to oral medications
• May require specific storage conditions

Understanding these comparisons can help healthcare providers and patients make informed decisions about the most appropriate medication form for specific conditions and individual needs.

Innovations in Suppository Technology

The field of suppository development continues to evolve, with researchers exploring new ways to enhance drug delivery and patient comfort:

Controlled-Release Formulations

Scientists are developing suppositories that can release medications over extended periods, potentially reducing the frequency of administration and improving treatment adherence.

Bioadhesive Suppositories

These innovative formulations adhere to the rectal or vaginal mucosa, increasing contact time and potentially improving drug absorption.

Nanoparticle-Based Suppositories

Incorporating nanoparticles into suppositories may enhance drug solubility and absorption, potentially leading to more effective treatments.

Temperature-Responsive Suppositories

These advanced formulations change their physical properties in response to body temperature, allowing for more precise control over drug release.

As research in this area progresses, we can expect to see suppositories become an even more versatile and effective drug delivery method, potentially expanding their use in various medical conditions.

Understanding the intricacies of how suppositories work, their typical onset of action, and proper administration techniques can significantly improve patient outcomes. While the time frame for suppositories to take effect can vary, most begin working within 15 to 60 minutes, with some requiring longer periods for full efficacy. By following proper administration techniques and being aware of potential factors influencing their effectiveness, patients can maximize the benefits of this unique drug delivery method. As with any medication, it’s crucial to consult with a healthcare provider for personalized advice and to report any unexpected side effects or concerns.

How do suppositories work? Uses, instructions, and pictures

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Medical News Today only shows you brands and products that we stand behind.

Our team thoroughly researches and evaluates the recommendations we make on our site. To establish that the product manufacturers addressed safety and efficacy standards, we:

• Evaluate ingredients and composition: Do they have the potential to cause harm?
• Fact-check all health claims: Do they align with the current body of scientific evidence?
• Assess the brand: Does it operate with integrity and adhere to industry best practices?

We do the research so you can find trusted products for your health and wellness.

Read more about our vetting process.

Was this helpful?

Suppositories are solid medications that enter the body through the rectum, vagina, or urethra. Rectal suppositories are the most common type of suppository.

Doctors recommend the different forms of suppositories for different medical conditions and purposes. People place some in the rectum and others in the vagina. Less commonly, a person will need to use urethral suppositories.

We give step-by-step guidance on how to use suppositories in this article.

We also provide some helpful troubleshooting tips and advice for people who need to use this type of medication.

Share on PinterestPeople use suppositories when they are unable to take drugs orally.

Suppositories are another way to deliver drugs to the body when other routes, such as oral, cannot be used.

A suppository is small and may be round, oval, or cone-shaped. A substance, such as cocoa butter or gelatin, surrounds the medication. The suppository dissolves to release the drug once inside the body.

Suppositories may treat the local area, or the medicine may travel to other parts of the body through the bloodstream.

Why use suppositories?

Suppositories deliver many types of medication, and a person may need to use them if they:

• are having seizures and cannot take medicines by mouth
• are unable to swallow medication for any reason
• are vomiting and cannot keep pills or liquids down
• have a blockage that stops the medication moving through the digestive system

People may also take suppositories if the medication:

• tastes too bad to take by mouth
• would break down too quickly in the gut
• could be destroyed in the gastrointestinal tract

Research also suggests that taking medications through the rectum allows for a relatively constant environment for a drug to be delivered. The rate of absorption may, however, be lower than that of drugs taken by mouth.

There are three types of suppositories:

Rectal suppositories

Rectal suppositories go in the rectum or anus. They are typically an inch long and have a rounded tip.

They treat conditions, such as:

• constipation
• fever
• hemorrhoids
• mental health issues such as anxiety, schizophrenia, or bipolar disorder
• nausea, including motion sickness
• pain

Vaginal suppositories

People may insert vaginal suppositories into the vagina to treat:

• bacterial or fungal infections
• vaginal dryness

Vaginal suppositories are typically oval and come with an applicator.

Urethral suppositories

Men may use a type of urethral suppository to treat erection problems in rare cases.

These suppositories are the size of a grain of rice and deliver a drug called alprostadil.

Anyone using a rectal suppository may want to refer to the following steps for guidance:

1. Get prepared

Share on Pinterest

• Try to pass stool to empty the colon, as suppository medication is most effective when the bowel is empty.
• Wash hands thoroughly with soap and warm water or use a hand sanitizer. Dry the hands thoroughly on a clean towel or paper towel.
• Carefully remove the suppository from its wrapper.
• If it is necessary to cut the suppository, use a clean, single-edge razor blade to slice it lengthwise.
• Use a disposable glove, if desired.

2. Get ready to insert the suppository

Share on Pinterest

• Dip the tip of the suppository in water, or apply a small amount of water-based lubricant, such as K-Y Jelly that is available to buy online. A lubricant helps the suppository more easily slide into the rectum.
• Remove clothing from the lower half of the body.
• Find the correct position. Either stand up with one foot on a chair or lie down on one side with the top leg bent slightly toward the stomach. Caregivers giving the suppository to another person often find it easier if the person is lying down.

3. Insert the suppository

Share on Pinterest

• Relax the muscles of the buttocks and open the cheeks.
• Gently insert the suppository into the anus, narrow end first.
• Push it in about 1 inch for adults, or half an inch for infants.
• In older children, push the suppository in approximately half to one inch, depending on their size.

4. Relax and clean up

Share on Pinterest

• Sit or lie still for 10 minutes after inserting the suppository. Staying still allows time for the suppository to dissolve in the body. Parents may need to hold a child’s buttocks closed during this time.
• Dispose of all materials, including the suppository wrapper and any tissue paper.
• Wash the hands thoroughly with soap and warm water.

Try to avoid passing stool for up to 60 minutes after inserting the suppository, unless it is a laxative. Not passing stool gives the medication enough time to enter the bloodstream and start working.

Share on Pinterest

To place a suppository into the vagina, follow these tips:

1. Get prepared

• Wash hands with soap and warm water, or use a hand sanitizer if these are not available. Dry the hands well on a clean towel or paper towel.
• Unwrap the suppository, and place it in the accompanying applicator.
• Either stand with the knees bent and feet apart or lie down with the knees bent toward the chest.

2. Insert the suppository

Share on Pinterest

• Place the applicator into the vagina, as far as possible, without causing discomfort.
• Press down on the plunger to push in the suppository.
• Remove the applicator from the vagina, and dispose of it.

3. Relax and clean up

• Lie down for 10 minutes to allow the medicine to enter the body.
• Wash the hands once more with soap and warm water.

Consider using a sanitary towel for a few hours, as some of the suppository may leak out onto the underwear.

To place a suppository into the urethra try the following tips:

1. Get prepared

• Empty the bladder.
• Wash the hands with soap and warm water or use a hand sanitizer. Dry the hands thoroughly on a clean towel or paper towel.
• Remove the applicator cover.

2. Insert the suppository

• Stretch out the penis to open the urethra.
• Place the applicator into the hole at the tip.
• Push the button on the applicator and hold for 5 seconds.
• Gently move the applicator from side to side to ensure the suppository has entered the urethra.
• Remove the applicator.

3. Relax and clean up

• Massage the stretched penis firmly for 10 to 15 seconds to allow the medicine to be absorbed.
• Dispose of the applicator and any other materials.
• Wash the hands once more with soap and warm water.

Suppositories are usually safe to use. Sometimes, some of the medication may leak out. To avoid a mess, people may want to wear a sanitary towel or incontinence pad.

Some people may experience irritation around the area where they inserted the suppository. If this is severe or persists, they should see a doctor.

Occasionally, the body may not absorb the medication delivered by a suppository as well as it does oral medications.

The following tips may help people who need to use suppositories:

• Avoid exercise or vigorous movement for 60 minutes after inserting the medication.
• Do not use petroleum jelly, such as Vaseline, to lubricate the suppository. This stops it from melting. Only use water, or a water-based lubricant.
• Store suppositories in the refrigerator or another cool place, so they do not melt. Always follow the storage directions on the label.
• A soft suppository can be difficult to insert. Gently squeeze it to see if it is firm enough. If not, harden the wrapped suppository by holding it under a flow of cold water. Or, place it in the refrigerator for a few minutes.
• Trim fingernails before inserting suppositories. This prevents cuts and scrapes. Alternatively, wear a latex glove.
• Some people may notice the suppository falls out. This can occur because they have not pushed it far enough into the rectum. Push the medication in about 1 inch.
• Those who struggle to use suppositories should consider asking a partner or caregiver for help.
• As with other medicines, avoid missing doses. Missed doses may reduce the effectiveness of the treatment.

Suppositories are helpful for people who cannot take medications by mouth.

People who have difficulty using suppositories should ask their doctor for advice. They should also talk to their doctor before using suppositories if they:

• have had recent rectal surgery, prostate surgery, or vaginal treatment
• have an irregular heartbeat

Although they may be unpleasant to use, rectal, vaginal, and urethral suppositories can be an effective way of delivering medication.

How do suppositories work? Uses, instructions, and pictures

We include products we think are useful for our readers. If you buy through links on this page, we may earn a small commission Here’s our process.

Medical News Today only shows you brands and products that we stand behind.

Our team thoroughly researches and evaluates the recommendations we make on our site. To establish that the product manufacturers addressed safety and efficacy standards, we:

• Evaluate ingredients and composition: Do they have the potential to cause harm?
• Fact-check all health claims: Do they align with the current body of scientific evidence?
• Assess the brand: Does it operate with integrity and adhere to industry best practices?

We do the research so you can find trusted products for your health and wellness.

Read more about our vetting process.

Was this helpful?

Suppositories are solid medications that enter the body through the rectum, vagina, or urethra. Rectal suppositories are the most common type of suppository.

Doctors recommend the different forms of suppositories for different medical conditions and purposes. People place some in the rectum and others in the vagina. Less commonly, a person will need to use urethral suppositories.

We give step-by-step guidance on how to use suppositories in this article.

We also provide some helpful troubleshooting tips and advice for people who need to use this type of medication.

Share on PinterestPeople use suppositories when they are unable to take drugs orally.

Suppositories are another way to deliver drugs to the body when other routes, such as oral, cannot be used.

A suppository is small and may be round, oval, or cone-shaped. A substance, such as cocoa butter or gelatin, surrounds the medication. The suppository dissolves to release the drug once inside the body.

Suppositories may treat the local area, or the medicine may travel to other parts of the body through the bloodstream.

Why use suppositories?

Suppositories deliver many types of medication, and a person may need to use them if they:

• are having seizures and cannot take medicines by mouth
• are unable to swallow medication for any reason
• are vomiting and cannot keep pills or liquids down
• have a blockage that stops the medication moving through the digestive system

People may also take suppositories if the medication:

• tastes too bad to take by mouth
• would break down too quickly in the gut
• could be destroyed in the gastrointestinal tract

Research also suggests that taking medications through the rectum allows for a relatively constant environment for a drug to be delivered. The rate of absorption may, however, be lower than that of drugs taken by mouth.

There are three types of suppositories:

Rectal suppositories

Rectal suppositories go in the rectum or anus. They are typically an inch long and have a rounded tip.

They treat conditions, such as:

• constipation
• fever
• hemorrhoids
• mental health issues such as anxiety, schizophrenia, or bipolar disorder
• nausea, including motion sickness
• pain

Vaginal suppositories

People may insert vaginal suppositories into the vagina to treat:

• bacterial or fungal infections
• vaginal dryness

Vaginal suppositories are typically oval and come with an applicator.

Urethral suppositories

Men may use a type of urethral suppository to treat erection problems in rare cases.

These suppositories are the size of a grain of rice and deliver a drug called alprostadil.

Anyone using a rectal suppository may want to refer to the following steps for guidance:

1.

Get prepared

Share on Pinterest

• Try to pass stool to empty the colon, as suppository medication is most effective when the bowel is empty.
• Wash hands thoroughly with soap and warm water or use a hand sanitizer. Dry the hands thoroughly on a clean towel or paper towel.
• Carefully remove the suppository from its wrapper.
• If it is necessary to cut the suppository, use a clean, single-edge razor blade to slice it lengthwise.
• Use a disposable glove, if desired.

2. Get ready to insert the suppository

Share on Pinterest

• Dip the tip of the suppository in water, or apply a small amount of water-based lubricant, such as K-Y Jelly that is available to buy online. A lubricant helps the suppository more easily slide into the rectum.
• Remove clothing from the lower half of the body.
• Find the correct position. Either stand up with one foot on a chair or lie down on one side with the top leg bent slightly toward the stomach. Caregivers giving the suppository to another person often find it easier if the person is lying down.

3. Insert the suppository

Share on Pinterest

• Relax the muscles of the buttocks and open the cheeks.
• Gently insert the suppository into the anus, narrow end first.
• Push it in about 1 inch for adults, or half an inch for infants.
• In older children, push the suppository in approximately half to one inch, depending on their size.

4. Relax and clean up

Share on Pinterest

• Sit or lie still for 10 minutes after inserting the suppository. Staying still allows time for the suppository to dissolve in the body. Parents may need to hold a child’s buttocks closed during this time.
• Dispose of all materials, including the suppository wrapper and any tissue paper.
• Wash the hands thoroughly with soap and warm water.

Try to avoid passing stool for up to 60 minutes after inserting the suppository, unless it is a laxative. Not passing stool gives the medication enough time to enter the bloodstream and start working.

Share on Pinterest

To place a suppository into the vagina, follow these tips:

1. Get prepared

• Wash hands with soap and warm water, or use a hand sanitizer if these are not available. Dry the hands well on a clean towel or paper towel.
• Unwrap the suppository, and place it in the accompanying applicator.
• Either stand with the knees bent and feet apart or lie down with the knees bent toward the chest.

2. Insert the suppository

Share on Pinterest

• Place the applicator into the vagina, as far as possible, without causing discomfort.
• Press down on the plunger to push in the suppository.
• Remove the applicator from the vagina, and dispose of it.

3. Relax and clean up

• Lie down for 10 minutes to allow the medicine to enter the body.
• Wash the hands once more with soap and warm water.

Consider using a sanitary towel for a few hours, as some of the suppository may leak out onto the underwear.

To place a suppository into the urethra try the following tips:

1. Get prepared

• Empty the bladder.
• Wash the hands with soap and warm water or use a hand sanitizer. Dry the hands thoroughly on a clean towel or paper towel.
• Remove the applicator cover.

2. Insert the suppository

• Stretch out the penis to open the urethra.
• Place the applicator into the hole at the tip.
• Push the button on the applicator and hold for 5 seconds.
• Gently move the applicator from side to side to ensure the suppository has entered the urethra.
• Remove the applicator.

3. Relax and clean up

• Massage the stretched penis firmly for 10 to 15 seconds to allow the medicine to be absorbed.
• Dispose of the applicator and any other materials.
• Wash the hands once more with soap and warm water.

Suppositories are usually safe to use. Sometimes, some of the medication may leak out. To avoid a mess, people may want to wear a sanitary towel or incontinence pad.

Some people may experience irritation around the area where they inserted the suppository. If this is severe or persists, they should see a doctor.

Occasionally, the body may not absorb the medication delivered by a suppository as well as it does oral medications.

The following tips may help people who need to use suppositories:

• Avoid exercise or vigorous movement for 60 minutes after inserting the medication.
• Do not use petroleum jelly, such as Vaseline, to lubricate the suppository. This stops it from melting. Only use water, or a water-based lubricant.
• Store suppositories in the refrigerator or another cool place, so they do not melt. Always follow the storage directions on the label.
• A soft suppository can be difficult to insert. Gently squeeze it to see if it is firm enough. If not, harden the wrapped suppository by holding it under a flow of cold water. Or, place it in the refrigerator for a few minutes.
• Trim fingernails before inserting suppositories. This prevents cuts and scrapes. Alternatively, wear a latex glove.
• Some people may notice the suppository falls out. This can occur because they have not pushed it far enough into the rectum. Push the medication in about 1 inch.
• Those who struggle to use suppositories should consider asking a partner or caregiver for help.
• As with other medicines, avoid missing doses. Missed doses may reduce the effectiveness of the treatment.

Suppositories are helpful for people who cannot take medications by mouth.

People who have difficulty using suppositories should ask their doctor for advice. They should also talk to their doctor before using suppositories if they:

• have had recent rectal surgery, prostate surgery, or vaginal treatment
• have an irregular heartbeat

Although they may be unpleasant to use, rectal, vaginal, and urethral suppositories can be an effective way of delivering medication.

Instructions, after how long they work, dosage, composition

Date of publication: 06.10.2022 POSSIBLE SIDE EFFECTS. A SPECIALIST’S CONSULTATION IS NECESSARY. Antipyretic for adults Antipyretic for children Antipyretic candles s

Article content

• Cefecon: composition
• Cefecon: active substance
• Cefecon suppositories: dosage
• Cefecon: suppositories for newborns
• Cefecon for teething
• Cefecon N: how long does it take to work
• Cefecon D: how long does it take to work
• Summary 9 0016
• Ask an expert about the topic of the article

It is no coincidence that autumn is nicknamed the “season of colds”. The warm summer period is leaving: holidays are ending, the air temperature is dropping, the day is getting shorter, and the workload is increasing. The body is rebuilt to a new mode and becomes vulnerable. It is estimated that annual autumn epidemics of viral diseases lead to 3-5 million cases of severe illness.

Bacteria and viruses attack the weakened immune system, causing a response – fever. It is sometimes difficult to deal with it, especially when it comes to children. Antipyretics come to the rescue, one of which will be discussed in this article.

Pharmacist Kristina Khokhrina will tell you about Cefecon, its composition, dosage, application and how long it takes to start working.

All products Tsefekon

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Tsefekon: composition

There are two types of candles against temperature Tsefekon: Tsefekon N and Tsefekon D (for children). Cefecon H is a combination drug containing caffeine, naproxen and salicylamide. It is used to treat and prevent fever in adults and children over 16 years of age. Cefecon D is paracetamol. It is used in children from 3 months to 12 years.

Cefecon: active ingredient

Both drugs have antipyretic, analgesic and anti-inflammatory effects, but this is achieved through different active ingredients. Cefecon N contains:

• Caffeine is a psychoactive component to eliminate drowsiness and fatigue, as well as increase physical and mental activity.
• Naproxen and salicylamide are anti-inflammatory ingredients that normalize body temperature and relieve pain.

Cefecon for Children contains paracetamol, a safe and well-tolerated antipyretic agent for children. Paracetamol is included in the list of clinical recommendations for the provision of emergency care for acute fever in children.

Cefecon suppositories: dosage

Cefecon is available in the form of suppositories – rectal suppositories. Note that suppositories are a safer dosage form than, for example, tablets. Suppositories cause fewer side effects because they do not enter the stomach, which means that nausea, vomiting and abdominal discomfort will not threaten patients. For the same reason, the effect of candles comes faster.

To use, it is necessary to remove the suppository from the packaging and insert it deep into the rectum, and then lie down for 30-40 minutes.

Cefecon H is used up to 3 times a day, but not more than 3 days in the fight against fever, and not more than 5 days in case of pain. Produced in a single dosage of 10 pieces per pack.

The dose of Cefecon for children is calculated depending on the weight and age of the child. So, for children from 1 to 3 years old weighing 11-16 kg, use 1 suppository of 100 mg. The interval between applications should be at least 6 hours, and the maximum dose should not exceed 60 mg/kg of the child’s weight. Available in 10 suppositories per pack in three dosages: 50, 100 and 250 mg.

Course duration: 3 days for fever and 5 days for pain. Candles are dispensed without a prescription, but it is still worth consulting with a doctor or pharmacist. The drug has contraindications, and an incorrectly calculated dose will lead to an overdose, the consequences of which will be severe.

Cefekon: suppositories for newborns

Newborns are children from the moment of birth until the 28th day of life. The use of Cefecon D during this period is possible, but only once and as directed by a doctor.

Suppositories are used in case of fever due to vaccinations, which are carried out up to 2 months. It is worth inserting a candle into the empty intestine, after warming it up in your hands.

Cefecon for teething

Teething in children begins at the age of 2 to 7 months and is accompanied not only by pain, but also by fever. In this case, Cefecon D will be an effective remedy that eliminates both violations. Candles will not affect the normal body temperature, so you should not be afraid of its excessive decrease.

Cefecon N: how long does it take to start working

Naproxen and salicylamide in Cefecon N allow you to quickly get rid of pain: the effect occurs within 30 minutes after application and lasts up to 8 hours. The anti-inflammatory effect develops within 1-2 weeks.

Cefecon D: how long does it take to act

The maximum effect of paracetamol in the composition of suppositories is achieved 2-3 hours after administration and lasts up to 6 hours.

Summary

• In autumn, the body adjusts to a new regimen and becomes vulnerable
• Cefekon anti-temperature suppositories are of two types: Cefekon N and Cefekon D (for children)
• Cefecon N contains: caffeine, naproxen and salicylamide
• Children’s Cefecon contains paracetamol
• Cefecon is available in the form of suppositories – rectal suppositories
• Cefecon N is used up to 3 times a day, no more than 3 days in the fight against fever, and no more than 5 days – with pain
• The dose of Cefecon for children is calculated depending on the weight and age of the child
• Cefecon D can be used for newborns, but only once and as prescribed by a doctor
• Cefecon D will be an effective remedy for teething in children
• The action of Cefecon N occurs already 30 minutes after application and lasts up to 8 hours
• The maximum effect of Cefecon D is achieved 2-3 hours after administration and lasts up to 6 hours

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Suppositories in gynecology: types and features of use

For the treatment and prevention of many gynecological diseases, local drugs are often prescribed, for example, suppositories. What is the advantage of such medicines?

“Drugs that are injected into the natural cavities of the body are used in complex therapy for the treatment of adnexitis, oophoritis, cervical erosion, colpitis, vaginitis, with polycystic ovaries, endometriosis, to eliminate violations of the vaginal microflora. In addition, suppositories are actively prescribed before and after various surgical interventions, before childbirth or the installation of intrauterine devices.

What explains such a wide range of applications and doctors’ commitment to this dosage form? The fact is that preparations in the form of suppositories have a number of significant advantages: they quickly dissolve and begin to act in the pathological focus, while not only having a therapeutic effect, but also preventing the further spread of the infection. In addition, with this method of treatment, there are practically no side effects that are possible with oral medication. Prescribing drugs in the form of suppositories is especially important if the patient has a history of disorders in the functioning of the liver, kidneys, gastrointestinal tract, cardiovascular system, ”obstetrician-gynecologist, endocrinologist of the GIMed Family Health Clinic Lidia Sheygas draws attention.

Types of suppositories and their mechanism of action

Suppositories are divided into two large groups: vaginal and rectal. According to the form of the introduction of the candle, there are several types. Vaginal are most often round, oval, and also in the form of a cone. Rectal suppositories are produced mainly in the form of a cone.

The composition always contains a solid base (paraffin, gelatin, glycerin), it is she who creates and holds the shape of the suppository, and the active substance. A feature of these drugs is their ability to maintain a solid consistency in the external environment and quickly turn into a liquid inside the body.

The main therapeutic advantage of suppositories is that they not only locally affect the focus of inflammation, but also have a general healing effect. It is known that the area of ​​the vagina and rectum is supplied with a huge number of blood vessels, so the active medicinal components enter the bloodstream very quickly and actively circulate in the pelvic area, while carrying out not only a local therapeutic effect. Biologically available medicinal substances become within 30-60 minutes.

Such therapy quickly relieves the symptoms of the disease, does not affect the menstrual cycle, secretion of gonadotropic hormones, carbohydrate and lipid metabolism. Candles are administered quickly and painlessly, and the use of this group of medicines is rarely accompanied by allergic reactions.

Command staff

As part of a suppository, the active substance can be both synthetic and natural, and also include antibiotics, antiseptics, antifungal and antiviral components, vitamins, probiotics and other substances that help strengthen local immunity. The appointment depends on the pathogenic agent that caused the gynecological disease (viruses, bacteria, fungi or protozoa).

Most suppositories have a complex mechanism of action and can simultaneously relieve the inflammatory process and affect pathogens.

Antibacterial suppositories. The main active ingredient of such drugs are metronidazole, co-trixomazol, penicillins, macrolides. The use of antibacterial drugs always has its own characteristics. If used incorrectly, such drugs can cause allergic reactions, cause oppression of the normal microflora of the vagina and reduce local protective reserves.

Antifungal suppositories . The most famous drugs are fluconazole, clotrimazole, natamycin. The course of treatment depends on many factors, therefore it is determined individually.

Anti-inflammatory suppositories – the main component is non-steroidal anti-inflammatory drugs – diclofenac, ichthyol or indomethacin. They not only relieve inflammation and swelling, but also anesthetize.

Such drugs, from a biological point of view, inhibit the production of prostaglandins, which are produced in large quantities during the inflammatory process and cause pain.

Suppositories with steroidal anti-inflammatory drugs (prednisolone) are less commonly used in gynecological practice.

The therapeutic course of inflammatory diseases lasts up to ten days.

Antiviral suppositories (protiflazid, interferon alfa-2b) are used in clinical practice for the treatment of genital herpes and human papillomavirus (HPV) as part of complex treatment. The therapeutic course is long, the duration of therapy will be determined by the attending physician.

Hormone-based preparations (estriol) – contribute to the restoration of hormonal balance, the pH level in the vagina, suppress the inflammatory process, strengthen the natural barrier, reduce the risk of relapses. The course of treatment is long, determined individually by the doctor.

Candles with natural ingredients , which include sea buckthorn oil, cocoa, eucalyptus, extracts of medicinal herbs, coniferous trees, are prescribed for pregnant women, during lactation, as well as for older people and children.

Suppository Administration: General Rules

It is recommended to administer suppositories at night, preferably before bedtime. Before using rectal suppositories, it is necessary to empty the intestines. The manipulation is carried out lying on its side, bending the legs at the knees and pressing them to the chest. But vaginal suppositories are injected to the maximum depth while lying on your back. Special applicators that are attached to suppositories greatly facilitate the process. After the introduction, you need to be in a horizontal position for at least twenty minutes. This time is enough to dissolve the candle.

The use of the suppository is contraindicated in case of allergic reactions to the components of the preparation.