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Trilafon side effects: Perphenazine (Trilafon) – Side Effects, Interactions, Uses, Dosage, Warnings

Trilafon Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Warnings:

There may be a slightly increased risk of serious, possibly fatal side effects (such as heart failure, fast/irregular heartbeat, pneumonia) when this medication is used by older adults with dementia. This medication is not approved for the treatment of dementia-related behavior problems. Discuss the risks and benefits of this medication, as well as other effective and possibly safer treatments for dementia-related behavior problems, with the doctor.

Warnings:

There may be a slightly increased risk of serious, possibly fatal side effects (such as heart failure, fast/irregular heartbeat, pneumonia) when this medication is used by older adults with dementia. This medication is not approved for the treatment of dementia-related behavior problems. Discuss the risks and benefits of this medication, as well as other effective and possibly safer treatments for dementia-related behavior problems, with the doctor.

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Uses

This medication is used to treat certain mental/mood disorders (such as schizophrenia, manic phase of bipolar disorder, schizoaffective disorder). This medicine helps you to think more clearly, feel less nervous, and take part in everyday life. It can reduce aggressive behavior and the desire to hurt yourself/others. It may also help to decrease hallucinations (such as hearing/seeing things that are not there). Perphenazine is a psychiatric medication (antipsychotic-type) that works by helping to restore the balance of certain natural substances (such as dopamine) in the brain.

How to use Trilafon Tablet

Take this medication by mouth with or without food as directed by your doctor, usually 1 to 3 times a day.

The dosage is based on your medical condition and response to treatment. Your doctor may direct you to take a low dose at first, gradually increasing the dose to lower the chance of side effects (such as muscle spasms). Follow your doctor’s directions carefully.

Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.

Although you may notice some medication effects soon after starting, it may take as much as 4-6 weeks of regular use to see the full benefit. Do not stop taking this medication without consulting your doctor. Your condition may become worse when the drug is suddenly stopped. Your dose may need to be gradually decreased.

Tell your doctor if your condition does not improve or if it worsens.

Side Effects

Drowsiness, constipation, dry mouth, dizziness, lightheadedness, blurred vision, tiredness, or unexplained weight gain may occur. If any of these effects last or get worse, notify your doctor or pharmacist promptly.

Dizziness and lightheadedness can increase the risk of falling. Get up slowly when rising from a sitting or lying position.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

This drug may cause muscle/nervous system problems (extrapyramidal symptoms-EPS). Your doctor may prescribe another medication to decrease these side effects. Tell your doctor right away if you notice any of the following side effects: increased anxiety, drooling/trouble swallowing, restlessness/constant need to move, shaking (tremor), shuffling walk, stiff muscles.

This medication may cause a condition known as tardive dyskinesia. In some cases, this condition may be permanent. Tell your doctor right away if you develop any involuntary/repetitive muscle movements such as lip smacking/puckering, tongue thrusting, chewing, or finger/toe movements.

In rare cases, perphenazine may increase your level of a certain chemical made by the body (prolactin). For females, this increase in prolactin may result in unwanted breast milk, missed/stopped periods, or difficulty becoming pregnant. For males, it may result in decreased sexual ability, inability to produce sperm, or enlarged breasts. If you develop any of these symptoms, tell your doctor right away.

Tell your doctor right away if you have any serious side effects, including: nausea that doesn’t stop, difficulty urinating, easy bruising/bleeding, slow heartbeat, signs of infection (such as sore throat), severe muscle spasm/cramping (such as twisting neck, arching back, eyes rolling up), seizures, stomach/abdominal pain, yellowing eyes/skin.

Get medical help right away if you have any very serious side effects, including: fast/irregular heartbeat, severe dizziness, fainting.

This medication may rarely cause a very serious condition called neuroleptic malignant syndrome (NMS). Get medical help right away if you have any of the following symptoms: fever, muscle stiffness/pain/tenderness/weakness, severe tiredness, severe confusion, sweating, fast/irregular heartbeat, dark urine, signs of kidney problems (such as change in the amount of urine).

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking perphenazine, tell your doctor or pharmacist if you are allergic to it, or to other phenothiazines (such as chlorpromazine, fluphenazine), or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: decreased bone marrow function, serious head injury, liver problems, nervous system problem (such as coma, drug/alcohol overdose, shock), Parkinson’s disease, history of alcohol/substance abuse, low blood pressure, breathing problems (such as asthma, emphysema), breast cancer, fast/irregular heartbeat, heart valve problems, a certain adrenal gland tumor (pheochromocytoma), restless legs syndrome, seizure disorder, a certain severe reaction to other medications (neuroleptic malignant syndrome), difficulty urinating (such as due to prostate problems).

Perphenazine may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.

The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using perphenazine, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).

Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics “water pills”) or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using perphenazine safely.

This drug may make you dizzy or drowsy or blur your vision. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).

This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. Tell your doctor right away if you get sunburned or have skin blisters/redness.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Caution is advised during hot weather because perphenazine can reduce sweating, increasing your risk for a severe reaction to too much heat (heatstroke). Drink plenty of fluids. Avoid strenuous exercise in hot weather. If you become overheated, promptly seek cooler shelter and/or stop exercising. Get medical help right away if your body temperature is above normal or if you have mental/mood changes, headache, or dizziness.

Children may be more sensitive to the side effects of this drug, especially uncontrolled movements.

Older adults may be more sensitive to the side effects of this drug, especially dizziness, lightheadedness, drowsiness, extrapyramidal symptoms, tardive dyskinesia, and QT prolongation (see above). Drowsiness, dizziness, and lightheadedness can increase the risk of falling.

During pregnancy, this medication should be used only when clearly needed. Babies born to mothers who have used this drug during the last 3 months of pregnancy may rarely develop symptoms including muscle stiffness or shakiness, drowsiness, feeding/breathing difficulties, or constant crying. If you notice any of these symptoms in your newborn especially during their first month, tell the doctor right away.

Since untreated mental/mood problems (such as schizophrenia, bipolar disorder, schizoaffective disorder) can be a serious condition, do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy.

Perphenazine passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

Some products that may interact with this drug are: certain drugs used for Parkinson’s (such as bromocriptine, levodopa, pergolide), certain anticholinergic medications (such as dicyclomine, scopolamine), drugs affecting liver enzymes that remove perphenazine from your body (such as amiodarone, duloxetine, fluoxetine, paroxetine, ritonavir).

Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana (cannabis), drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine).

Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

Does Trilafon Tablet interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: slow/shallow breathing, inability to wake up (coma).

Do not share this medication with others.

Lab and/or medical tests (such as complete blood count, liver function, eye exams) should be done while you are taking this medication. Keep all medical and lab appointments. Consult your doctor for more details.

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

Trilafon (Perphenazine) Patient Information | HealthyPlace

Find out why Trilafon is prescribed, side effects of Trilafon, Trilafon warnings, effects of Trilafon during pregnancy, more – in plain English.

Pronounced: TRILL-ah-fon

Full Trilafon Prescription Information

Why is Trilafon prescribed?

Trilafon is used to treat schizophrenia and to control severe nausea and vomiting in adults. It is a member of the phenothiazine family of antipsychotic medications, which includes such drugs as Mellaril, Stelazine, and Thorazine.

Most important fact about Trilafon

Trilafon can cause tardive dyskinesia, a condition marked by involuntary muscle spasms and twitches in the face and body, including chewing movements, puckering, puffing the cheeks, and sticking out the tongue. This condition may be permanent and appears to be most common among older adults, especially older women. Ask your doctor for more information about this possible risk.

How should you take Trilafon?

Trilafon should be taken exactly according to physician instructions and for no longer than necessary.

–If you miss a dose…

If it is within an hour or so after the scheduled time, take the forgotten dose as soon as you remember. If you do not remember until later, skip the dose and go back to your regular schedule. Never take 2 doses at once.

 

–Storage instructions…

Trilafon should be stored at room temperature.

What side effects may occur with Trilafon?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe to continue taking Trilafon.


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  • Trilafon side effects may include: Allergic reactions, asthma, bizarre dreams, blood disorders, blurred vision, body spasms, breast enlargement in males and females, breast milk production, cardiac arrest, changes in sex drive, confusion, constipation and intestinal problems, diarrhea, difficulty swallowing, dizziness, drowsiness, dry mouth, exaggerated reflexes, eye changes and disorders, faintness, false-positive pregnancy test results, fast or slow heartbeat, fever, fixed stare, headaches, high or low blood pressure, high or low blood sugar, high pressure in the eyes, hives, hyperactivity, inappropriate excitement, increased appetite and weight, inhibition of ejaculation, insomnia, irregular heartbeat, itching, large or small pupils, lethargy, light sensitivity, limb aches, liver problems, lockjaw, loss of appetite, loss of coordination, lupus-like symptoms, menstrual irregularities, muscle weakness, nasal congestion, nausea, numbness, pallor, paranoia, Parkinsonism (rigidity and tremors), protruding or aching tongue, restlessness, salivation, seizures, skin rash or redness, slurred speech, stupor, sweating, swelling of the arms and legs, swelling of the ear, swelling of the face or throat, tardive dyskinesia (see Most important fact), tics, throat tightness, twisting or spasms of the neck and mouth muscles, urinary problems, yellow skin or eyes, vomiting
Why should Trilafon not be prescribed?

People who are comatose or who are at reduced levels of consciousness or alertness should not take Trilafon. Nor should those who are taking large amounts of any substance that slows brain function, including barbiturates, alcohol, narcotics, pain killers, and antihistamines.

Trilafon should also be avoided by people who have blood disorders, liver problems, or brain damage It cannot be taken by anyone who is hypersensitive to its ingredients or to related drugs.

Special warnings about Trilafon

Drugs such as Trilafon are capable of triggering a potentially fatal condition known as Neuroleptic Malignant Syndrome. Symptoms include high fever, muscle rigidity, altered mental status, unstable blood pressure, a rapid or irregular heartbeat, and excessive sweating. If any of these symptoms develop, see your doctor immediately; Trilafon therapy should be discontinued.

Also report any significant increase in body temperature to the doctor. It could be an early warning that you cannot tolerate the drug.

Alert your physician before taking Trilafon if you are going through alcohol withdrawal, suffer from convulsions or seizures, or have a depressive disorder. You’ll have to use the drug with caution.

Caution is also warranted if you have kidney problems or trouble breathing. The doctor will periodically monitor your kidney and liver function and check your blood count for possible side effects.

Be sure to let the doctor know if you’ve ever had breast cancer. Trilafon stimulates production of a hormone that promotes the growth of certain types of tumors.

Be aware that Trilafon may impair the mental or physical abilities needed to drive a car or operate heavy machinery. Also, avoid prolonged exposure to the sun since Trilafon may increase sensitivity to light.

Stomach inflammation, dizziness, nausea, vomiting, and tremors may result if Trilafon is stopped suddenly. Therapy should be discontinued only under a doctor’s supervision.

Trilafon is not recommended for children under the age of 12 years.

Possible food and drug interactions when taking Trilafon

If Trilafon is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Trilafon with the following:

Antidepressants such as Elavil, Nardil, and Prozac Antihistamines such as Benadryl and Tavist Antipsychotic medications such as Mellaril and Thorazine Antiseizure drugs such as Dilantin Barbiturates such as Nembutal and Seconal Drugs that quell spasms, such as Donnatal and Levsin Narcotic painkillers such as Percodan and Vicodin Phosphorus insecticides Tranquilizers and sleep aids such as Halcion, Valium, and Xanax

Because Trilafon prevents vomiting, it can hide the signs and symptoms of overdose of other drugs.

If you are scheduled for an operation, be sure to tell the surgeon that you are taking Trilafon, since it may change the amount of anesthesia you require.

Special information if you are pregnant or breastfeeding

Safe use of Trilafon during pregnancy and breastfeeding has not been established. The possible benefits of taking Trilafon must be weighed against the possible hazards to mother and child.

Recommended dosage for Trilafon

The dosage of Trilafon is adjusted according to the severity of the condition and the drug’s effect. Doctors aim for the lowest effective dose

SCHIZOPHRENIA

The usual initial dosage of Trilafon tablets is 4 to 8 milligrams 3 times daily, up to a maximum daily dose of 24 milligrams. Hospitalized patients are usually given 8 to 16 milligrams 2 to 4 times daily, up to a maximum daily dose of 64 milligrams.

SEVERE NAUSEA AND VOMITING IN ADULTS

For this problem, the usual dosage of Trilafon tablets is 8 to 16 milligrams daily divided into smaller doses. Up to 24 milligrams daily is occasionally necessary.

Overdosage of Trilafon

Anyone suspected of having taken on overdose of Trilafon should be hospitalized immediately for emergency treatment.

  • Usual symptoms of Trilafon overdose include: Stupor, coma, convulsions (in children)

Victims may also exhibit symptoms such as rigid muscles, twitches and involuntary movements, hair-trigger reflexes, loss of coordination, rolling eyeballs, and slurred speech.

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Full Trilafon Prescription Information

Detailed Info on Signs, Symptoms, Causes, Treatments of Schizophrenia

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APA Reference
Staff, H.
(2009, January 3). Trilafon (Perphenazine) Patient Information, HealthyPlace. Retrieved
on 2023, June 29 from https://www.healthyplace.com/other-info/psychiatric-medications/trilafon-perphenazine-patient-information

Memorial Sloan Kettering Cancer Center

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Provided by Lexicomp ® , this document contains all the information you need to know about this medicine, including indications, directions for use, side effects, and when your healthcare provider should be contacted.

Trade names: Canada

APO-Tryptophan; DOM-Tryptophan; TEVA-Tryptophan; Tryptan

What is this drug used for?

  • Used to treat depression in people with bipolar disorder.
  • This drug may also be used for other indications. Consult your doctor.

What should I tell my doctor BEFORE taking this drug?

  • If you have an allergy to this drug, any of its ingredients, other drugs, foods or substances. Tell your doctor about your allergies and how they have manifested.
  • If you have taken certain drugs in the past 14 days that are indicated for either depression, such as isocarboxazid, phenelzine, or tranylcypromine, or Parkinson’s disease, such as rasagiline. Taking this drug less than 14 days after you last took any of the above drugs can cause high blood pressure.
  • If you are taking any of the following drugs: linezolid or methylene blue.

This list of drugs and conditions that may interact with this drug is not exhaustive.

Tell your doctor and pharmacist about all medicines you take (prescription and over-the-counter, natural products and vitamins) and any health problems you have. You need to make sure that this drug is safe for your conditions and in combination with other drugs you are already taking. Do not start or stop taking any drug or change the dosage without your doctor’s advice.

What do I need to know or do while taking this drug?

  • Tell all your health care workers that you are taking this drug. These are doctors, nurses, pharmacists and dentists.
  • Avoid driving and other activities that require increased attention until you see how this drug affects you.
  • Check with your doctor before using alcohol, marijuana or other forms of cannabis, or prescription or over-the-counter drugs that can slow you down.
  • Take vitamin B6 (pyridoxine) as directed by your doctor.
  • If you have high blood sugar (diabetes), you should check your blood sugar regularly.
  • In rare cases, cataract formation is possible.
  • Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding. The benefits and risks for you and your child will need to be discussed.

What side effects should I report to my doctor immediately?

WARNING. In rare cases, this drug can cause serious and sometimes deadly side effects in some patients. Contact your doctor or seek medical attention right away if you have any of the following signs or symptoms that may be associated with serious side effects:

  • Signs of an allergic reaction such as rash, hives, itching, red and swollen skin with blisters or peeling, possibly in combination with fever, wheezing or wheezing, tightness in the chest or throat, difficulty breathing, swallowing or speaking, unusual hoarseness, swelling in the mouth, face, lips, tongue or throat.
  • Muscle pain.
  • Inflammation.
  • Violation of sexual function.
  • Vision change.
  • When this drug is taken with certain other drugs, a bad and sometimes deadly condition called serotonin syndrome can develop. Call your doctor right away if you experience agitation, balance problems, confusion, hallucinations, high fever, tachycardia or abnormal heart rhythms, flushing, muscle twitching or stiffness, seizures, tremors or tremors, excessive sweating, severe diarrhea, nausea or vomiting , severe headache.

What are some other side effects of this drug?

Any medicine can have side effects. However, for many people, side effects are either minor or non-existent. Contact your doctor or seek medical attention if these or any other side effects bother you or do not go away:

  • Dry mouth.
  • Feeling dizzy or sleepy.
  • Nausea.
  • Decreased appetite.
  • Headache.

This list of possible side effects is not exhaustive. If you have any questions about side effects, please contact your doctor. Talk to your doctor about side effects.

You can report side effects to the National Health Board.

You can report side effects to the FDA at 1-800-332-1088. You can also report side effects at https://www.fda.gov/medwatch.

What is the best way to take this drug?

Use this drug as directed by your doctor. Read all the information provided to you. Strictly follow all instructions.

  • Take with meals or snacks.

What if I miss a dose of a drug?

  • Take the missed dose as soon as you can.
  • If it’s time for your next dose, don’t take the missed dose and then go back to your regular dosing schedule.
  • Do not take 2 doses or an additional dose at the same time.

How do I store and/or discard this drug?

  • Store at room temperature, protected from light. Store in a dry place. Do not store in the bathroom.
  • Keep all medicines in a safe place. Keep all medicines out of the reach of children and pets.
  • Dispose of unused or expired drugs. Do not empty into a toilet or sewer unless instructed to do so. If you have any questions about disposing of medicines, ask your pharmacist. Drug disposal programs may be in place in your area.

General information about medicines

  • If your health does not improve or even worsens, see your doctor.
  • Do not give your medicine to anyone and do not take other people’s medicines.
  • Some medicines may come with other patient information leaflets. If you have questions about this drug, talk with your doctor, nurse, pharmacist, or other health care professional.
  • Some medicines may come with other patient information leaflets. Check with your pharmacist. If you have questions about this drug, talk with your doctor, nurse, pharmacist, or other health care professional.
  • If you think you have overdosed, call a poison control center or get medical help right away. Be prepared to tell or show what drug you took, how much, and when it happened.

Consumer Use of Information and Limitation of Liability

This summary information includes a summary of the diagnosis, treatment, and/or drug product. It is not intended to be a comprehensive source of data and should be used as a tool to help the user understand and/or evaluate potential diagnostic and treatment options. It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a particular patient. It should not be considered medical advice or a substitute for medical advice, diagnosis or treatment provided by a physician based on a medical examination and assessment of the patient’s specific and unique circumstances. Patients should consult with their physician for full information about their health, medical issues, and treatment options, including any risks or benefits regarding the use of medications. This information is not a guarantee that a treatment or drug is safe, effective, or approved for a particular patient. UpToDate, Inc. and its subsidiaries disclaim any warranties or liabilities related to this information or its use. The use of this information is subject to the Terms of Use found at https://www. wolterskluwer.com/en/know/clinical-effectiveness-terms.

Last revision date

2021-08-25

Copyright

© UpToDate, Inc. and its affiliates and/or licensors, 2023. All rights reserved.

Date last updated

Monday, December 12, 2022

benefits, harms, sources, rules for taking supplements?

Tryptophan is an essential amino acid involved in protein metabolism and reactions that produce serotonin, melatonin and choline. It is not formed in the body, but enters it with food. Tryptophan deficiency can cause serious health problems, lead to the development of chronic insomnia and have a negative impact on the regulation of cognitive functions, mood and behavior. Therefore, in some cases, doctors prescribe drugs and dietary supplements containing this substance.

Products containing tryptophan

This amino acid is present in the following foods:

  • meat;
  • dairy products;
  • brewer’s yeast;
  • mushrooms;
  • bananas;
  • fish;
  • legumes;
  • cereals;
  • nuts;
  • dates.

    Benefit

    Tryptophan has a positive effect on mood and performance. Its use improves the condition of the skin and hair, and also normalizes sleep.

    Harm

    Not only the lack of tryptophan is harmful, but also its excess. In such a situation, the development of serotonin syndrome or an overdose is possible. Its manifestations are anxiety, dyspepsia and apathy.

    Composition with tryptophan

    Typically, these dietary supplements include cellulose, gelatin, glycerin, water, calcium and sodium salts. The active substance is the isometric L-form of tryptophan.

    Some imported preparations contain l-tryptophan 5-hydroxide (oxytriptan). This is an intermediate substance formed during the synthesis of tryptophan and serotonin. It is prescribed for the treatment of migraines, PMS in women and some eating disorders.

    Who is assigned?

    It is not recommended to take tryptophan without first consulting your doctor. The indications for which it is prescribed are:

    1. Complex therapy for alcohol and drug addiction to relieve withdrawal symptoms. Tryptophan reduces anxiety and improves sleep.
    2. Insomnia. Tryptophan helps to establish the correct biorhythms.
    3. Lack of this substance in the body.

    The latter is usually accompanied by protein-energy malnutrition. In such cases, a complex intake of essential amino acids is required. For this, Cytovir-3 is usually prescribed, containing alpha-glutamyl-tryptophan in combination with bendazole and ascorbic acid. The drug has an immunostimulating and antiviral effect. It is used for the prevention and treatment of SARS and influenza.

    How to take?

    For insomnia, tryptophan is used in an amount of 1-3 grams immediately before bedtime. For those who suffer from withdrawal symptoms, it is prescribed in the amount of 1-4 grams. This dose is taken in 4 divided doses throughout the day.