Methyl salicylate topical Uses, Side Effects & Warnings

Generic name: methyl salicylate topical [ METH-il-sa-LISS-il-ate-TOP-ik-al ]
Brand names: BENGAY Arthritis, Boroleum, Castiva Cooling, Eucalyptamint, Exocaine Plus,
… show all 53 brands
Gordogesic, Heet Triple Action, Icy Hot, Salonpas Pain Patch, Satogesic, Thera-Gesic, Absorbine Jr., Wintergreen Oil, BENGAY Ultra, Analgesic Balm, Menthol C, Arthricare Cream, BENGAY Original, Salonpas Pain Gel, Salonpas Pain Spray, Banalg, Heet Analgesic Liniment, Mentholatum Pain Patch, Mentholatum Pain Gel, Penetran Pain Relieving, Satogesic Pad, Satogesic Hot Gel, Deep Down Pain Relief, Nephro-Derm, Cooling Gel, Absorbine Jr. Extra Strength, Ben Gay, Vaporizing Cold Rub, Flex-All 454, Pain Stick Arthritis Formula, Pain Stick Sports Formula, Minit Rub, Thera-P Blue, Analgesic Balm Greaseless, BENGAY Vanishing Scent, Banalg Hospital Strength, Panalgesic Gold, Therapeutic Pain Relief, Cold and Hot Pain Relief, Thera-Gesic Extra Plus, PainZone, duraflex comfort, Salonpas Pain Relief Patch, Salonpas Arthritis Pain, Precise Pain Relieving, Ultra Strength Muscle Rub, Aloe Vera Liniment, Coats Aloe Analgesic Liniment

Dosage forms: topical cream (-), topical film (-), topical gel (-), topical liquid (-), topical lotion (-), topical oil (-), topical ointment (-),
. .. show all 9 dosage forms
topical spray (-), topical stick (-)

Drug class: Topical rubefacient

Medically reviewed by Drugs.com on Dec 15, 2021. Written by Cerner Multum.

What is methyl salicylate topical?

Methyl salicylate topical (for the skin) is used for temporary relief of minor aches and pains caused by strains, sprains, arthritis, bruising, nerve pain, simple backache, or pain in the lower spine.

Methyl salicylate topical may also be used for purposes not listed in this medication guide.

Warnings

Follow all directions on the label and package. Use exactly as directed.

Before taking this medicine

Ask a doctor or pharmacist if methyl salicylate topical is safe to use if you have ever had an allergy (especially to aspirin or other salicylates).

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

If you breastfeed, avoid applying this medicine to your nipple area.

Do not use this medicine on a child without medical advice.

How should I use methyl salicylate topical?

Use exactly as directed on the label, or as prescribed by your doctor.

Do not take by mouth. Topical medicine is for use only on the skin.

Apply only to clean and dry skin. Avoid applying over large areas of skin.

Do not apply to an open wound or to skin that is blistered, sunburned, windburned, otherwise irritated.

Only certain forms of this medicine are for use in young children. Follow all directions when using this medicine on a child.

Apply a thin layer of medicine to the painful area and rub in gently.

Apply the skin patch over the area of pain and press the edges firmly. Remove the patch and apply a new one as directed.

Shake the spray well just before each use.

Wash your hands with soap and water after applying this medicine or handling a skin patch. To keep from getting this medicine on your fingers, apply it using a rubber glove, finger cot, cotton ball, or clean tissue.

If using the medicine to treat an area of your hands or fingers, wait at least 30 minutes before washing your hands.

Do not cover treated skin with a bandage or heating pad.

Stop using this medicine and call your doctor if your pain does not improve after 7 days, or if your symptoms get worse or get better and then come back in a few days.

Store at room temperature away from moisture, heat, and direct sunlight.

What happens if I miss a dose?

Methyl salicylate topical is used when needed. If you are on a dosing schedule, skip any missed dose. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medicine.

What should I avoid while using methyl salicylate topical?

Avoid getting methyl salicylate topical in your eyes. If contact does occur, rinse with water. Also avoid getting the medicine in your nose, mouth, rectum, or vagina.

Also avoid getting the medicine on contact lenses, dentures, and other items that come in contact with sensitive areas of your body.

Avoid using other medications on the same treatment areas without medical advice.

Methyl salicylate topical side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

This medicine may cause serious side effects. Stop using this medicine and call your doctor at once if you have:

• redness or swelling of the treated area;

• increased pain; or

• severe burning or skin irritation such as a rash, itching, pain, or blistering.

Less serious side effects may be more likely, and you may have none at all.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect methyl salicylate topical?

Medicine used on the skin is not likely to be affected by other drugs you use, but many drugs can interact. Tell your doctor about all your current medicines, including prescription and over-the-counter medicines, vitamins, and herbal products.

More about methyl salicylate topical

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• Reviews (143)
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• Drug class: topical rubefacient

Patient resources

• Patient Information

Other brands

Salonpas Pain Patch, Eucalyptamint, Boroleum, Castiva Cooling, … +5 more

Related treatment guides

• Osteoarthritis
• Muscle Pain
• Rheumatoid Arthritis

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Copyright 1996-2023 Cerner Multum, Inc. Version: 3.02.

Methyl Salicylate Topical (Icy Hot)

Brand Names:Absorbine Jr., Absorbine Jr. Extra Strength, Aloe Vera Liniment, Analgesic Balm, Analgesic Balm Greaseless, Arthricare Cream

Reviewed: December 15, 2021

Methyl salicylate topical (for the skin) is used for temporary relief of minor aches and pains caused by strains, sprains, arthritis, bruising, nerve pain, simple backache, or pain in the lower spine.

Methyl salicylate topical may also be used for purposes not listed in this medication guide.

warnings

What is the most important information I should know about Methyl Salicylate Topical (Icy Hot)?

Ask a doctor or pharmacist if this medicine is safe to use if you have ever had an allergy (especially to aspirin or other salicylates).

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

If you breastfeed, avoid applying this medicine to your nipple area.

Do not use this medicine on a child without medical advice.

Side Effects

What are the side effects of Methyl Salicylate Topical (Icy Hot)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

• redness or swelling of the treated area;
• increased pain; or
• severe burning or skin irritation such as a rash, itching, pain, or blistering.

Less serious side effects may be more likely, and you may have none at all.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I take Methyl Salicylate Topical (Icy Hot) if I’m pregnant or breastfeeding?

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

If you breastfeed, avoid applying this medicine to your nipple area.

Interactions

What drugs and food should I avoid while taking Methyl Salicylate Topical (Icy Hot)?

Avoid getting this medicine in your eyes. If contact does occur, rinse with water. Also avoid getting the medicine in your nose, mouth, rectum, or vagina.

Also avoid getting the medicine on contact lenses, dentures, and other items that come in contact with sensitive areas of your body.

Avoid using other medications on the same treatment areas without medical advice.

Dosage Guidelines & Tips

How to take Methyl Salicylate Topical (Icy Hot)?

Use Methyl Salicylate Topical (Icy Hot) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Use exactly as directed on the label, or as prescribed by your doctor.

Do not take by mouth. Topical medicine is for use only on the skin.

Apply only to clean and dry skin. Avoid applying over large areas of skin.

Do not apply to an open wound or to skin that is blistered, sunburned, windburned, otherwise irritated.

Only certain forms of this medicine are for use in young children. Follow all directions when using this medicine on a child.

Apply a thin layer of medicine to the painful area and rub in gently.

Apply the skin patch over the area of pain and press the edges firmly. Remove the patch and apply a new one as directed.

Shake the spray well just before each use.

Wash your hands with soap and water after applying this medicine or handling a skin patch. To keep from getting this medicine on your fingers, apply it using a rubber glove, finger cot, cotton ball, or clean tissue.

If using the medicine to treat an area of your hands or fingers, wait at least 30 minutes before washing your hands.

Do not cover treated skin with a bandage or heating pad.

Stop using this medicine and call your doctor if your pain does not improve after 7 days, or if your symptoms get worse or get better and then come back in a few days.

Store at room temperature away from moisture, heat, and direct sunlight.

What should I do if I missed a dose of Methyl Salicylate Topical (Icy Hot)?

Methyl salicylate topical is used when needed. If you are on a dosing schedule, skip any missed dose. Do not use two doses at one time.

Overdose Signs

What happens if I overdose on Methyl Salicylate Topical (Icy Hot)?

If you think you or someone else may have overdosed on: Methyl Salicylate Topical (Icy Hot),  call your doctor or the Poison Control center

(800) 222-1222

If someone collapses or isn’t breathing after taking Methyl Salicylate Topical (Icy Hot), call 911

911

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Medical Disclaimer

Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. Cerner Multum™ provides the data within some of the Overview, Uses, Warnings, Side Effects, Pregnancy, Interactions, Dosage, Overdose, and Images sections. The information within all other sections is proprietary to Everyday Health. 

Methyl salicylate – description of the substance, pharmacology, use, contraindications, formula

Contents

• Structural formula

• Russian name

• English name

• Latin name

• chemical name

• Gross formula

• Pharmacological group of the substance Methyl salicylate

• Nosological classification

• CAS code

• pharmachologic effect

• Characteristic

• Pharmacology

• Application of the substance Methyl salicylate

• Contraindications

• Application restrictions

• Side effects of the substance Methyl salicylate

• Interaction

• Overdose

• Dosage and administration

• Precautionary measures

• Trade names with the active substance Methyl salicylate

Structural formula

Russian name

Methyl salicylate

English name

Methylsalicylate

Latin name

Methylii salicylas ( 9006 1 genus Methylii salicylatis)

Chemical name

Methyl ester of salicylic acid.

Generic formula

C ₈ H ₈ O ₃

Pharmacological group of the substance Methyl salicylate

NSAIDs – Derivatives of salicylic acid

Nosological classification

ICD-10 code list

CAS code

119-36-8

Pharmacological action

Pharmacological action 9 0095-

analgesic , anti-inflammatory .

Characteristics

Colorless or yellowish liquid with a characteristic aromatic odour. Methyl salicylate is very slightly soluble in water, miscible with ethanol and ether in all proportions. Density 1.176–1.184.

Pharmacology

Non-selectively inhibits cyclooxygenase, reduces PG synthesis. Normalizes increased capillary permeability, improves microcirculation, reduces swelling and infiltration of inflamed tissues. With local application, it quickly penetrates into the deep layers of the skin, is absorbed, hydrolyzed and converted into an anion of salicylic acid.

Application of the substance Methyl salicylate

Arthritis (including rheumatic), myalgia, exudative pleurisy.

Contraindications

Hypersensitivity (including to other derivatives of salicylic acid).

Restrictions for use

Pregnancy, children.

Side effects of the substance Methyl salicylate

Irritation at the site of application, allergic skin reactions.

Interaction

Enhances the effect of anticoagulants.

Overdose

Possible in children and when applied to large areas of the skin.

Symptoms: headache, tinnitus, visual disturbances, nausea, vomiting, diarrhea, epigastric pain, respiratory alkalosis or metabolic acidosis, hyperthermia, hypokalemia, hyperglycemia.

Treatment: correction of electrolyte and water balance, forced diuresis, external body cooling; in severe cases – blood transfusion, hemodialysis.

Dosage and administration

Apply topically to the skin over the affected area of ​​the joints and rub in lightly.

Precautions

Do not apply to broken skin. To prevent acute intoxication with salicylates, rubbing large amounts should be avoided (especially for children and pregnant women).

Trade names with active substance Methyl salicylate

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Methyl salicylate | it’s… What is Methyl Salicylate?

Methyl salicylate (Methylii salicylas) is a methyl ester of salicylic acid. Synonyms – Methylis salicylas, Methylium salicylicum.

In this article Methyl salicylate is considered as a drug (it is also the trade name of the drug in Russia and its INN).

General information

Application history

Methyl salicylate has been isolated as the main component from the oil of wintergreen and the essential oil of cherry birch. As part of these oils, the widespread medical use of methyl salicylate was begun.

General properties

A colorless volatile liquid with a strong characteristic odour, the main component of vinaigrette essential oil, currently mainly synthetic methyl salicylate is used. Applied externally as an analgesic and anti-inflammatory agent per se and mixed with chloroform, turpentine oil, fatty oils for rubbing in articular and muscular rheumatism, arthritis, exudative pleurisy.

In addition, the following finished dosage forms containing methyl salicylate are available.

• Linimentum (Balsamum) “Sanitas”]. Contains: methyl salicylate 24 g, eucalyptus oil 1.2 g, purified turpentine oil 3.2 g, camphor 5 g, lard and vaseline 33.3 g each.
• Nayatox ointment
• Bom-Benge ointment (Unguentum Boum-Benge). Contains: menthol 3.9 g (or peppermint oil 7.8 g), methyl salicylate 20.2 g, medical vaseline 68.9 g, medical paraffin 7 g (per 100 g).
• Liniment “Naftalgin” (Linimentum “Naphthalginum”). Contains methyl salicylate, analgin and Naftalan oil 2.5 parts each, a mixture of fatty alcohols of sperm whale oil 3 parts, an emulsifier 13 parts, water up to 100 parts.
• Capsin (Capsinum). Liniment containing methyl salicylate 1 part, bleached oil and tincture of capsicum 2 parts each.
• Methyl salicylate liniment complex (Linimentum methylii salicylatis compositum). Contains methyl salicylate and chloroform 33.3 g each, bleached (or dope) oil 33.4 g (per 100 g).
• Salinimentum (Salinimentum). Contains: methyl salicylate and chloroform 20 g each, bleached (or dope) oil 60 g (per 100 g).