How does desmopressin work to control urine production. What are the potential side effects of desmopressin. Who should exercise caution when using desmopressin. How is desmopressin administered for different conditions.

Understanding Desmopressin: A Synthetic Vasopressin Analogue

Desmopressin is a synthetic analogue of vasopressin, a naturally occurring hormone that plays a crucial role in regulating the body’s water balance. This medication is primarily used to manage conditions related to excessive urination and fluid imbalance. By mimicking the effects of natural vasopressin, desmopressin helps control urine production and maintain proper hydration levels in the body.

The primary uses of desmopressin include:

• Treatment of central diabetes insipidus
• Management of nocturnal enuresis (bedwetting) in children
• Control of excessive urination following certain types of head injuries or brain surgeries

Can desmopressin effectively replace low levels of natural vasopressin? Yes, desmopressin is designed to mimic the effects of vasopressin in the body, making it an effective treatment for conditions where natural vasopressin production is insufficient.

Mechanism of Action: How Desmopressin Controls Urine Production

Desmopressin works by binding to specific receptors in the kidneys, known as V2 receptors. This interaction triggers a series of cellular responses that ultimately lead to increased water reabsorption in the kidneys. As a result, the volume of urine produced is reduced, and the urine becomes more concentrated.

The key effects of desmopressin on the body include:

1. Increased water reabsorption in the collecting ducts of the kidneys
2. Reduced urine output
3. Increased urine concentration
4. Regulation of blood plasma osmolality

How quickly does desmopressin take effect? The onset of action for desmopressin is relatively rapid, with effects typically observed within 1-2 hours after administration. The duration of action can vary depending on the dosage form and individual patient factors.

Dosage and Administration: Tailoring Treatment to Specific Conditions

The dosage and administration of desmopressin vary depending on the specific condition being treated and the individual patient’s needs. It is crucial to follow the prescribed dosage regimen carefully to ensure optimal efficacy and minimize the risk of side effects.

For Diabetes Insipidus:

Typically, desmopressin is administered orally 2 to 3 times daily for the treatment of diabetes insipidus. The exact dosage is determined by the physician based on the patient’s response to treatment and the severity of the condition.

For Nocturnal Enuresis:

In the management of bedwetting in children, desmopressin is usually taken once daily at bedtime. It is essential to limit fluid intake after dinner, especially in the hour before taking the medication and for at least 8 hours after the dose.

Is fluid restriction necessary when taking desmopressin? Yes, limiting fluid intake is crucial, particularly for children and older adults, to prevent the risk of water intoxication and hyponatremia. Patients should consult their healthcare provider for specific guidelines on fluid restriction.

Potential Side Effects: Recognizing and Managing Adverse Reactions

While desmopressin is generally well-tolerated, it can cause various side effects. It is essential for patients and caregivers to be aware of these potential adverse reactions and report any concerning symptoms to their healthcare provider promptly.

Common side effects of desmopressin may include:

• Headache
• Nausea
• Upset stomach
• Flushing of the face

Are there any serious side effects associated with desmopressin use? Yes, while rare, serious side effects can occur. These may include severe allergic reactions, seizures, and hyponatremia (low sodium levels in the blood). Patients should seek immediate medical attention if they experience symptoms such as difficulty breathing, severe dizziness, or confusion.

Hyponatremia: A Serious Concern with Desmopressin Use

One of the most significant risks associated with desmopressin use is the potential development of hyponatremia, a condition characterized by abnormally low sodium levels in the blood. This complication can be serious and, in rare cases, even fatal.

Factors that may increase the risk of hyponatremia include:

• Excessive fluid intake
• Concurrent use of certain medications (e.g., diuretics, glucocorticoids)
• Advanced age (65 years or older)
• Certain medical conditions

How can the risk of hyponatremia be minimized? Regular monitoring of sodium blood levels and urine output is essential. Patients should adhere strictly to fluid intake guidelines provided by their healthcare provider and report any symptoms of hyponatremia promptly.

Precautions and Contraindications: Ensuring Safe Use of Desmopressin

Before initiating desmopressin therapy, it is crucial to consider various precautions and potential contraindications to ensure the safe and effective use of the medication.

Medical Conditions Requiring Caution:

• History of hyponatremia
• Cardiovascular diseases
• Renal impairment
• Cystic fibrosis
• Conditions associated with fluid or electrolyte imbalance

Should patients with a history of seizures use desmopressin? Patients with a history of seizures should use desmopressin with caution, as the medication can potentially increase the risk of seizure activity, especially if hyponatremia develops.

Drug Interactions:

Desmopressin may interact with various medications, potentially affecting its efficacy or increasing the risk of side effects. Some medications that may interact with desmopressin include:

• Diuretics
• NSAIDs (e.g., ibuprofen, naproxen)
• Selective serotonin reuptake inhibitors (SSRIs)
• Carbamazepine
• Chlorpromazine

Is it safe to use desmopressin during pregnancy or breastfeeding? Limited data is available on the use of desmopressin during pregnancy and lactation. Patients should consult their healthcare provider to weigh the potential risks and benefits before using desmopressin during these periods.

Monitoring and Follow-up: Ensuring Optimal Treatment Outcomes

Regular monitoring and follow-up are essential components of desmopressin therapy to ensure optimal treatment outcomes and minimize the risk of complications. Healthcare providers typically recommend periodic assessments to evaluate the medication’s efficacy and monitor for potential side effects.

Key Monitoring Parameters:

• Serum sodium levels
• Urine output and concentration
• Fluid intake and balance
• Blood pressure
• Symptoms of hyponatremia or other adverse effects

How often should patients undergo laboratory testing while on desmopressin therapy? The frequency of laboratory testing may vary depending on individual patient factors and the specific condition being treated. Generally, more frequent monitoring is required during the initial stages of treatment or when dosage adjustments are made.

Patient Education:

Proper patient education is crucial for the safe and effective use of desmopressin. Healthcare providers should ensure that patients and caregivers understand:

1. The importance of adhering to prescribed dosage regimens
2. Guidelines for fluid restriction
3. Signs and symptoms of hyponatremia and other potential side effects
4. The need for regular follow-up appointments and laboratory tests
5. Proper storage and handling of the medication

Can lifestyle modifications complement desmopressin therapy? Yes, certain lifestyle modifications can enhance the effectiveness of desmopressin treatment. These may include adjusting fluid intake patterns, avoiding alcohol consumption, and managing stress levels, depending on the specific condition being treated.

Alternative Treatments and Complementary Approaches

While desmopressin is a primary treatment option for conditions such as diabetes insipidus and nocturnal enuresis, alternative treatments and complementary approaches may be considered in certain cases or as adjuncts to desmopressin therapy.

For Diabetes Insipidus:

• Thiazide diuretics
• Nonsteroidal anti-inflammatory drugs (NSAIDs)
• Dietary modifications (e.g., low-sodium diet)

For Nocturnal Enuresis:

• Behavioral interventions (e.g., bladder training, reward systems)
• Alarm therapy
• Psychological counseling

Are there any natural alternatives to desmopressin for managing excessive urination? While some natural remedies, such as herbal diuretics or acupuncture, have been suggested for managing urinary issues, their efficacy in treating conditions like diabetes insipidus or nocturnal enuresis is not well-established. Patients should consult their healthcare provider before attempting any alternative treatments.

In conclusion, desmopressin is a valuable medication for managing conditions related to excessive urination and fluid imbalance. Its effectiveness in treating central diabetes insipidus and nocturnal enuresis has been well-documented. However, the potential for serious side effects, particularly hyponatremia, necessitates careful monitoring and patient education. By understanding the mechanism of action, proper dosing, potential risks, and the importance of regular follow-up, healthcare providers and patients can work together to optimize the benefits of desmopressin therapy while minimizing potential complications.

DDAVP Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Warnings:

Desmopressin can rarely cause a low level of sodium in the blood (hyponatremia), which can be serious or even fatal. Drinking too much liquid, using certain medications (such as “water pills”/diuretics including furosemide, glucocorticoids such as prednisone), being 65 years or older, or having certain medical conditions may increase the risk of low sodium in the blood. Lab tests (such as urine tests, sodium blood levels) must be done before you start using this medication and while you are using it. Keep all medical and lab appointments.

Tell your doctor right away if you develop symptoms of low sodium in the blood, such as nausea, vomiting, headache, muscle weakness/cramps, unusual tiredness, unusual drowsiness, dizziness, restlessness, mental/mood changes including confusion/irritability.

Get medical help right away if you have any very serious side effects, including seizure or trouble breathing.

Warnings:

Desmopressin can rarely cause a low level of sodium in the blood (hyponatremia), which can be serious or even fatal. Drinking too much liquid, using certain medications (such as “water pills”/diuretics including furosemide, glucocorticoids such as prednisone), being 65 years or older, or having certain medical conditions may increase the risk of low sodium in the blood. Lab tests (such as urine tests, sodium blood levels) must be done before you start using this medication and while you are using it. Keep all medical and lab appointments.

Tell your doctor right away if you develop symptoms of low sodium in the blood, such as nausea, vomiting, headache, muscle weakness/cramps, unusual tiredness, unusual drowsiness, dizziness, restlessness, mental/mood changes including confusion/irritability.

Get medical help right away if you have any very serious side effects, including seizure or trouble breathing.

… Show More

Uses

Desmopressin is used to control the amount of urine your kidneys make. Normally, the amount of urine you make is controlled by a certain substance in the body called vasopressin. In people who have “water diabetes” (diabetes insipidus) or certain kinds of head injury or brain surgery, the body does not make enough vasopressin. Desmopressin is a man-made form of vasopressin and is used to replace a low level of vasopressin. This medication helps to control increased thirst and too much urination due to these conditions, and helps prevent dehydration.Desmopressin is also used to control nighttime bedwetting in children. It reduces how often your child urinates and decreases the number of bedwetting episodes.

How to use DDAVP

For the treatment of diabetes insipidus, take this medication by mouth, usually 2 to 3 times a day or as directed by your doctor.

For the treatment of bedwetting, take this medication by mouth, usually once a day at bedtime. Children should limit the fluids they drink after dinner, especially 1 hour before the desmopressin dose until the next morning, or at least 8 hours after the dose. If your child wakes up during the night, limit the amount that your child drinks.

All patients taking desmopressin, especially children and older adults, must limit drinking of water and other fluids. Consult your doctor for details. If you find that you are drinking more fluids than directed, tell your doctor right away. Your treatment will need to be adjusted.

Dosage is based on your medical condition and response to treatment. Do not take more desmopressin or take it more often than prescribed.

Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.

Tell your doctor if your condition does not improve or if this medication stops working well.

Side Effects

See also Warning section.

Headache, nausea, upset stomach, or flushing of the face may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking desmopressin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, high blood pressure, heart problems (such as blocked blood vessels, heart failure), conditions that may increase your risk of fluid/mineral imbalance (such as cystic fibrosis), the urge to drink too much water without being thirsty, a low level of sodium in the blood (hyponatremia), bleeding/clotting problems.

If you become dehydrated, your doctor will correct that condition first before starting treatment with desmopressin.

Limit alcohol because it can interfere with how well desmopressin works.

Tell the doctor right away if you develop any illness that can cause water/mineral imbalance (including fever, diarrhea, vomiting, infections such as the flu) or if you experience conditions that require drinking more fluids (for example, exposure to very hot weather, strenuous exercise, heavy sweating). The doctor may need to stop or adjust desmopressin treatment, especially in children and older adults.

Children may be more sensitive to the side effects of this drug, especially water/mineral imbalance and a low level of sodium in the blood.

Older adults may be at greater risk for water/mineral imbalance and a low level of sodium in the blood while using this drug.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

This medication passes into breast milk. Consult your doctor before breast-feeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

Some products that may interact with this drug are: tolvaptan, “water pills”/diuretics (such as furosemide).

Does DDAVP interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: headache that is severe or doesn’t go away, confusion, drowsiness, sudden weight gain.

Do not share this medication with others.

Lab and/or medical tests (such as urine tests, sodium blood level) may be done while you are taking this medication. Keep all medical and lab appointments. Consult your doctor for more details.

If you take 1 dose daily and miss a dose, take it as soon as you remember. If you do not remember until the next day, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

If you take more than 1 dose daily and miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

tolvaptan oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Warnings:

Treatment with this drug should be started or restarted in a hospital for proper monitoring. If your level of sodium in the blood is raised too quickly, it may cause a serious (even fatal) condition called osmotic demyelination syndrome. The risk is higher if you have liver disease, poor nutrition, or if you use/abuse alcohol. Tell your doctor right away if you have symptoms such as trouble speaking/swallowing, mental/mood changes (such as confusion), weakness/involuntary movement in the arms/legs, or seizures.

Do not use this medication to treat a certain kidney problem (autosomal dominant polycystic kidney disease-ADPKD). Due to the risk of serious liver damage, you must be in a special program for you to take this medication to treat ADPKD. Ask your doctor for details.

How to use Tolvaptan 30 Mg Tablet Antidiuretic Hormone Antagonists

Read the Medication Guide provided by your pharmacist before you start using tolvaptan and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, usually once daily. You should not take this medication for longer than 30 days.

To prevent dehydration, always have water ready to drink while taking tolvaptan. Drink when you are thirsty unless otherwise directed by your doctor.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Do not stop and restart this medication on your own. You may need to go back to a hospital to restart this medication. Tell your doctor right away if you stop taking this medication for any reason.

Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely. Grapefruit can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details.

The dosage is based on your medical condition and response to treatment.

Side Effects

See also Warning section.

Thirst, dry mouth, loss of appetite, constipation, or weakness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Dehydration can occur. The risk is increased if you have vomiting or diarrhea that doesn’t stop, and you cannot drink normally. Contact your doctor right away if you notice any symptoms of dehydration, such as fast heartbeat or dizziness/lightheadedness.

People with severe liver disease (cirrhosis) may have increased risk of bleeding from the stomach or intestines while taking this medication. Tell your doctor right away if you have any of the following symptoms: black/bloody stools, vomit that contains blood or looks like coffee grounds.

Tolvaptan may rarely cause serious (possibly fatal) liver disease. Get medical help right away if you have any symptoms of liver damage, such as: nausea/vomiting that doesn’t stop, loss of appetite, stomach/abdominal pain, yellowing eyes/skin, dark urine.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking tolvaptan, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, liver disease, trouble urinating (such as due to enlarged prostate, blockage, inability to make urine), use/abuse of alcohol.

To prevent dehydration while taking this medication, you must be able to replace fluids by drinking. Before taking this medication, tell your doctor if you are not able to drink normally or if you cannot feel if you are thirsty. (See also How to Use section.)

This medication may rarely make your blood sugar rise, which can cause or worsen diabetes. If you have diabetes, check your blood sugar regularly as directed and share the results with your doctor. Your doctor may need to adjust your diabetes medication, exercise program, or diet.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Consult your pharmacist or physician.

Interactions

See also How to Use section.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

A product that may interact with this drug is: desmopressin.

Other medications can affect the removal of tolvaptan from your body, which may affect how tolvaptan works. Examples include azole antifungals (such as ketoconazole, itraconazole), cobicistat, HIV protease inhibitors (such as lopinavir), macrolide antibiotics (such as clarithromycin, erythromycin), ribociclib, rifamycins (such as rifabutin, rifampin), ritonavir, St. John’s wort, drugs used to treat seizures (such as carbamazepine, phenytoin), among others.

Does Tolvaptan 30 Mg Tablet Antidiuretic Hormone Antagonists interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Do not share this medication with others.

Lab and/or medical tests (such as levels of sodium/potassium in the blood) should be done while you are taking this medication. Keep all medical and lab appointments.

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

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Fidelity Pills – KP.

RU

Komsomolskaya Pravda

Search results :00

Scientists are encouraging: a substance has been found that can be used to create a drug against adultery

As it turned out, as many as two issues of the “Man and Woman” column, which were devoted to scientific searches for the causes of going to the left and ways to stop them, did not cover the whole variety of topics (“Is there a cure for infidelity?”, “Coercion to fidelity”, see “KP” of September 6 and 13, 2008). Recently, new discoveries have arrived. And they testify: not only instincts and psychology are involved in adultery. But also chemistry. A substance has been discovered that averts fornication and generates a sense of fidelity to a single partner. Thanks to him, according to scientists, next to us there are people who can not change.

Cheating genes

The search for the chemical causes of infidelity began about seven years ago. And, as usual, from experiments on mice. Fortunately, among these animals there are two amazing populations – meadow voles and steppe voles. The males of the first are extremely lascivious, mating right and left. And those from the second, all their mouse life remain faithful to one female. Scientists decided to figure out why such a miracle happens. And they seem to have figured it out.

“Our study, in a relatively simple biological model, provides evidence that boosting the activity of just one gene profoundly changes the foundations of social behavior,” said Larry Young, a professor at Emory University in Georgia.

It turned out that the heads of faithful and unfaithful mice contain a different number of receptors that perceive the hormone vasopressin. It is produced by the brain in one area, and absorbed in another. This hormone, scientists have suggested, and generates a sense of attachment. Moreover, it creates a very pleasant feeling that one female is enough to satisfy sexual needs. The bold hypothesis was also reinforced by the fact that the faithful mice showed an excess of both the hormone itself and the receptors that perceive it.

To test, American neuroscientists transferred the gene responsible for vasopressin receptors from monogamous steppe voles to meadow lovers to go left. And a fantastic transformation happened: the Casanova mice became faithful “husbands” without exception. This is the magical power of chemistry.

People are like mice

Impressive results were obtained back in 2004. But since they belonged to “simple biological models”, they did not create confidence that they could be transferred to more complex ones – to people. Doubts were dispelled by recent research conducted at the Swedish Karolinska Institute under the direction of Professor Hass Walum. Scientists have discovered a striking similarity between people and their smaller brothers in terms of the chemical nature of adultery. It turned out that the human brain interacts with vasopressin in exactly the same way as the mouse. Faithful men found more of the hormone, and it was absorbed better. For cheaters, the opposite is true. And the reason is the same – the genetic difference of one from the other.

Conclusions: vasopressin has a serious claim to be the human hormone of fidelity. This is first. Secondly, not all men are cheaters. There is a breed of people in whom nature has beaten off the inclination to fornication, while retaining both the libido and the ability to receive sincere satisfaction from sexual intercourse with a single partner. Such, according to opinion polls, from a quarter to a third of the stronger sex.

Alas, it is still a mystery whether there is a genetic difference between women of easy sexual behavior and those who profess marital fidelity.

Prescribe me, doctor…

Vasopressin is a known hormone. News – its role in human relationships and in influencing social behavior. Naturally, the question arises: is it possible, on the basis of this hormone, to create a drug for the “treatment” of infidelity? Theoretically – yes, scientists answer. But more research is needed. After all, it is stupid to drink vasopressin or inject it dangerously. Like any hormone. Yes, and there are side effects – the most famous, for example, difficult urination (analogs of vasopressin are prescribed for patients with enuresis). Would a healthy husband in this sense want to make such a sacrifice? However, medical science does not stand still. Scientists will come up with something – synthetically harmless. And make humanity happy with fidelity pills.

Vladimir LAGOVSKY

SPECIALIST’S OPINION

Dilute with tenderness!

Natalya GRIDASOVA, psychoendocrinologist, doctor of the highest category:

– Vasopressin belongs to a group of hormones that are produced by a very important part of the brain – the pituitary gland, and is responsible for regulating the amount of fluids in the body. And disinhibited sexual behavior (simply – pathological infidelity) is often distinguished by people who have just the same function of the pituitary gland.

Of course, one cannot say directly, they say, inject your “walker” with vasopressin, and he will sit beside you like silk. But perhaps there is a rational grain in these studies. And the medicine “for infidelity” will act just on those men who run to the left not because of natural depravity or because the partner does not suit, but “due to illness.”

Vasopressin also affects the secretion of oxytocin, the hormone of tenderness, which is responsible for the emotional component of sexual relations and enhances attachment to a partner.

In large doses, vasopressin greatly increases pressure in tissues, including the brain, and this can be very dangerous for health.

Elena IONOVA.

BTW

Sleep well

Endocrinologists at the Faculty of Medicine of the University of Lübeck, led by Jan Born, discovered that inhaling an aerosol preparation containing vasopressin in the morning and evening has a hypnotic effect. But it also weakens memory.

In principle, an attractive combination of side effects: a faithful husband sleeps well, pees little and does not remember insults.

Maybe scientists are trying in vain? There is little demand for chastity pills. Slightly higher than on a baldness balm. It is strange, however… Although there are suspicions that in our sociological survey mainly traitors participated, for whom some kind of “non-leftist” is a threat to a lustful lifestyle. Like bromine for Casanova. Or do people really cope with adultery non-drug? Through love and willpower? And rely on natural feelings? Showing no interest even in a love potion?

Another interpretation is not ruled out. Logically sound. After all, if you restore a peppy and fresh look, become smart and slender teetotalers, then other problems – partner’s infidelity, baldness and insufficient attention of the opposite sex – will seem secondary and easily solved. This is what Faust thought when he sold his soul. Looks like we haven’t changed much since then?

Vladimir Lagovsky is waiting for your feedback on our website.

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