What are the potential side effects of vitamin B-12 supplements. How much vitamin B-12 do you need daily. What foods are high in vitamin B-12. When should you consult a doctor about vitamin B-12 supplementation.

Understanding Vitamin B-12: Essential Nutrient for Health

Vitamin B-12, also known as cobalamin, is a crucial water-soluble vitamin that plays a vital role in various bodily functions. It is essential for the formation of red blood cells, DNA synthesis, and proper neurological function. While most people obtain sufficient amounts of vitamin B-12 through their diet, some individuals may require supplements to maintain optimal levels.

This comprehensive guide will explore the benefits, potential side effects, and dosage recommendations for vitamin B-12 supplements, as well as natural food sources and when to seek medical advice.

The Benefits of Vitamin B-12 Supplementation

Vitamin B-12 supplements can offer numerous health benefits, particularly for individuals who are deficient or at risk of deficiency. Some of the key advantages include:

• Improved energy levels and reduced fatigue
• Enhanced cognitive function and memory
• Support for healthy nerve function
• Promotion of cardiovascular health
• Assistance in the production of red blood cells
• Potential mood enhancement and reduction of depressive symptoms

Do vitamin B-12 supplements benefit everyone equally? While most healthy individuals obtain sufficient B-12 from their diet, certain groups may particularly benefit from supplementation. These include older adults, vegetarians and vegans, individuals with gastrointestinal disorders, and those taking certain medications that interfere with B-12 absorption.

Potential Side Effects of Vitamin B-12 Supplements

While vitamin B-12 is generally considered safe when taken as directed, some individuals may experience side effects, particularly when consuming high doses or using injectable forms. Common side effects of vitamin B-12 supplements include:

• Mild diarrhea
• Itching or skin rash
• Headache
• Dizziness
• Nausea and vomiting
• Sensation of swelling

Can vitamin B-12 supplements cause more serious side effects? In rare cases, high doses of vitamin B-12 or injectable forms may lead to more severe complications, such as:

• Pulmonary edema and congestive heart failure (early in treatment)
• Vein thrombosis
• Polycythemia vera (a rare, slow-growing blood cancer)

It’s important to note that these serious side effects are extremely uncommon and typically occur only with excessive doses or in individuals with pre-existing health conditions.

Allergic Reactions to Vitamin B-12

Although rare, some individuals may experience allergic reactions to vitamin B-12 supplements. These reactions can range from mild to severe and may include symptoms such as:

• Swelling of the face, tongue, and throat
• Difficulty swallowing or breathing
• Hives or itching
• Rapid heartbeat

If you experience any signs of an allergic reaction after taking vitamin B-12 supplements, seek immediate medical attention or call emergency services.

Recommended Dosage and Administration of Vitamin B-12

The appropriate dosage of vitamin B-12 varies depending on factors such as age, health status, and the reason for supplementation. According to the National Institutes of Health, the recommended dietary allowances (RDAs) for vitamin B-12 are as follows:

• 2.4 micrograms (mcg) daily for individuals aged 14 years or older
• 2.6 mcg daily for pregnant women
• 2.8 mcg daily for breastfeeding women

How much vitamin B-12 should older adults take? For individuals over the age of 50, it’s recommended to obtain the RDA through fortified foods or supplements containing 25 to 100 mcg of B-12, as absorption efficiency may decrease with age.

It’s essential to consult with a healthcare professional before starting any supplementation regimen, especially if you have underlying health conditions or are taking medications that may interact with vitamin B-12.

Forms of Vitamin B-12 Supplements

Vitamin B-12 supplements are available in various forms, including:

• Oral tablets or capsules
• Sublingual tablets or lozenges
• Nasal gels
• Injectable solutions (typically administered by healthcare professionals)

The choice of supplement form depends on individual needs, absorption capabilities, and healthcare provider recommendations.

Natural Food Sources of Vitamin B-12

While supplements can be beneficial for some individuals, obtaining nutrients from whole foods is generally preferable. Vitamin B-12 is naturally found in animal-based products and some fortified foods. Rich dietary sources of vitamin B-12 include:

• Eggs
• Cheese and other dairy products
• Fish and shellfish
• Liver and kidney
• Red meat
• Fortified breakfast cereals
• Nutritional yeast

Are there plant-based sources of vitamin B-12? While vitamin B-12 is primarily found in animal products, some plant-based foods are fortified with B-12, making them suitable for vegetarians and vegans. These may include certain non-dairy milk alternatives, meat substitutes, and fortified cereals.

Interactions Between Vitamin B-12 and Other Substances

Certain medications and supplements can interfere with the absorption or effectiveness of vitamin B-12. It’s crucial to be aware of these potential interactions and discuss them with your healthcare provider. Some substances that may interact with vitamin B-12 include:

• Colchicine
• Metformin
• Proton pump inhibitors
• Vitamin C
• Chloramphenicol
• H2 blockers
• Aminosalicylic acid
• Folic acid supplements

How can you minimize potential interactions? If you’re taking any of these medications or supplements, your healthcare provider may recommend taking vitamin B-12 at a different time of day to ensure optimal absorption. For example, you might take vitamin B-12 in the morning and other medications in the evening.

Recognizing Vitamin B-12 Deficiency: Signs and Symptoms

Vitamin B-12 deficiency can lead to various health issues if left untreated. Recognizing the signs and symptoms of B-12 deficiency is crucial for early intervention. Common symptoms include:

• Fatigue and weakness
• Shortness of breath
• Dizziness
• Pale or jaundiced skin
• Smooth tongue
• Numbness or tingling in hands and feet
• Difficulty walking (balance problems)
• Mood changes or depression
• Memory problems

Who is at higher risk of vitamin B-12 deficiency? Certain groups are more susceptible to B-12 deficiency, including:

• Older adults
• Vegans and vegetarians
• Individuals with gastrointestinal disorders (e.g., Crohn’s disease, celiac disease)
• Those who have undergone weight loss surgery
• People taking certain medications (e.g., metformin, proton pump inhibitors)

If you suspect you may have a vitamin B-12 deficiency, consult your healthcare provider for proper diagnosis and treatment.

When to Consult a Healthcare Professional

While vitamin B-12 supplements are generally safe for most people, there are situations where professional medical advice is necessary. Consider consulting a healthcare provider in the following circumstances:

• Before starting any new supplement regimen
• If you experience persistent or severe side effects from B-12 supplements
• If you have a pre-existing medical condition or are taking medications that may interact with B-12
• If you’re pregnant or breastfeeding
• If you suspect you may have a B-12 deficiency
• If you’re considering B-12 injections

What questions should you ask your healthcare provider about vitamin B-12? When discussing B-12 supplementation with your doctor, consider asking:

• Is vitamin B-12 supplementation necessary for me?
• What is the appropriate dosage for my specific needs?
• Are there any potential interactions with my current medications?
• Should I consider dietary changes to increase my B-12 intake?
• How often should I have my B-12 levels checked?

By maintaining open communication with your healthcare provider, you can ensure that your vitamin B-12 supplementation is safe, effective, and tailored to your individual needs.

Monitoring Vitamin B-12 Levels: Testing and Follow-up

Regular monitoring of vitamin B-12 levels is essential for individuals who are at risk of deficiency or those taking supplements. Blood tests can accurately measure serum B-12 levels and help healthcare providers determine if supplementation is necessary or if adjustments to the current regimen are needed.

How often should vitamin B-12 levels be checked? The frequency of B-12 testing depends on individual factors such as age, health status, and risk of deficiency. Generally, adults over 50 and those with known risk factors may benefit from annual testing. Your healthcare provider can recommend an appropriate testing schedule based on your specific situation.

Types of Vitamin B-12 Tests

Several tests can be used to assess vitamin B-12 status:

• Serum B-12 test: Measures the amount of B-12 in the blood
• Methylmalonic acid (MMA) test: Can detect B-12 deficiency at the cellular level
• Holotranscobalamin (holoTC) test: Measures the active form of B-12 available for cell use
• Complete blood count (CBC): Can identify anemia associated with B-12 deficiency

Your healthcare provider will determine which test or combination of tests is most appropriate for assessing your vitamin B-12 status.

Alternative Approaches to Boosting Vitamin B-12 Levels

While supplements are a common method of addressing vitamin B-12 deficiency, there are alternative approaches to increasing B-12 levels naturally. These strategies can be particularly beneficial for individuals who prefer to avoid supplements or those looking to complement their supplementation regimen.

Dietary Modifications

Incorporating more B-12-rich foods into your diet is an effective way to boost your intake. Consider the following dietary changes:

• Increase consumption of lean meats, poultry, and fish
• Include more dairy products and eggs in your meals
• Choose fortified cereals and plant-based milk alternatives
• Experiment with organ meats like liver (in moderation)
• Try nutritional yeast as a flavor enhancer in various dishes

Improving Absorption

Enhancing your body’s ability to absorb vitamin B-12 can help maximize the benefits of dietary sources. Consider these strategies:

• Consume B-12-rich foods with a source of intrinsic factor (naturally present in the stomach)
• Address any underlying gastrointestinal issues that may impair absorption
• Manage stress levels, as chronic stress can affect nutrient absorption
• Limit alcohol consumption, which can interfere with B-12 absorption

Can lifestyle changes impact vitamin B-12 levels? While diet is the primary factor in B-12 status, certain lifestyle modifications may support overall health and nutrient absorption:

• Regular exercise to improve circulation and nutrient delivery
• Adequate sleep to support overall health and metabolism
• Stress reduction techniques such as meditation or yoga
• Avoiding smoking, which can interfere with nutrient absorption

By combining these alternative approaches with appropriate supplementation (if necessary), you can optimize your vitamin B-12 levels and support overall health and well-being.

Vitamin B-12 Side Effects

Vitamin B-12 Side Effects

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Medically reviewed by Alan Carter, Pharm. D. — By Emily Cronkleton — Updated on February 15, 2023

Your doctor will give you the right dosage of vitamin B-12 supplement, especially if you will inject it. Taking too much can cause side effects like nausea, headache, dizziness, and in rarely, blood clots or cancer.

Everyone needs vitamin B-12, and most people get enough through their diet. However, it’s important to know what side effects occur when you take too much.

Vitamin B-12 is water-soluble and absorbed in the intestines. After it’s absorbed, it’s used to make DNA and red blood cells. Vitamin B-12 that isn’t being used is stored in the liver. But if you take supplements, you might ingest more than your body needs.

Oral vitamin B-12 is safe to take at recommended doses for healthy people.

Injectable vitamin B-12, which is used to treat significant deficiencies, can cause the following side effects:

• mild diarrhea
• itching
• skin rash
• headache
• dizziness
• nausea
• vomiting
• pulmonary edema and congestive heart failure early in treatment
• vein thrombosis
• sensation of swelling
• polycythemia vera (rare, slow growing blood cancer)

Vitamin B-12 can cause very rare but serious allergic reactions (anaphylaxis). This includes swelling of the face, tongue, and throat, and difficulty swallowing and breathing. If this occurs after you take vitamin B-12, call 911 or your local emergency services immediately.

Some agents are linked to reduced absorption or serum levels of vitamin B-12. You may need vitamin B-12 supplements if you take any of the following:

• colchicine
• metformin
• proton pump inhibitors
• vitamin C
• chloramphenicol
• h3 blockers
• aminosalicylic acid

Folic acid supplements may interfere with vitamin B-12. Be sure to tell your doctor if you take folic acid.

You may need to take vitamin B-12 separately from the above drugs and supplements — say, one in the morning and one at night — so you can get the full dose of vitamin B-12.

Don’t take vitamin B-12 supplements if you have sensitivities or allergies to vitamin B-12, cobalt, and any other ingredients. Vitamin B-12 is safe to take in recommended dosages if you’re pregnant or breastfeeding.

If you notice any adverse effects after you start taking vitamin B-12 supplements, you should discontinue use immediately. Seek medical attention if your symptoms get worse or are severe.

You can consult your doctor to establish an appropriate dose if it’s determined that you don’t get enough B-12 from food sources.

According to the National Institutes of Health, the recommended dietary amounts (RDAs) are as follows:

• 2.4 micrograms (mcg) daily for ages 14 years or older
• 2.6 mcg daily for pregnant women
• 2.8 mcg daily for breastfeeding women

If you’re over the age of 50, you should try to get your RDA by eating foods with B-12 or by taking a supplement containing 25 to 100 mcg of B-12.

Foods with vitamin B-12 include:

• eggs
• cheese
• fish
• shellfish
• liver
• kidney
• red meat

See your doctor if you have bothersome side effects that don’t go away once you stop taking the supplements. Avoid taking supplements if possible, and try to get B-12 from food sources.

If you develop any side effects from taking vitamin B-12, you can stop taking the supplement and the symptoms should subside.

After this, you’ll need to determine either an appropriate dose or how to get the vitamin B-12 you need from food sources. You can discuss this with your doctor.

Last medically reviewed on August 9, 2019

How we reviewed this article:

Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.

• Cyanocobalamin – cyanocobalamin injection. (2018).
  dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a66eb3c4-3e1d-4d49-b963-4fa2334cc9b6
• Vitamin B-12. (2017).
  mayoclinic.org/drugs-supplements-vitamin-b12/art-20363663
• Vitamin B12: Fact sheet for health professionals. (2018).
  ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/

Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available.

Current Version

Feb 15, 2023

Written By

Emily Cronkleton

Edited By

Frank Crooks

Aug 9, 2019

Medically Reviewed By

Alan Carter, PharmD

Share this article

Medically reviewed by Alan Carter, Pharm.D. — By Emily Cronkleton — Updated on February 15, 2023

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Vitamin B-12 Side Effects

Vitamin B-12 Side Effects

• Health Conditions
  • Featured
    • Breast Cancer
    • IBD
    • Migraine
    • Multiple Sclerosis (MS)
    • Rheumatoid Arthritis
    • Type 2 Diabetes
  • Articles
    • Acid Reflux
    • ADHD
    • Allergies
    • Alzheimer’s & Dementia
    • Bipolar Disorder
    • Cancer
    • Crohn’s Disease
    • Chronic Pain
    • Cold & Flu
    • COPD
    • Depression
    • Fibromyalgia
    • Heart Disease
    • High Cholesterol
    • HIV
    • Hypertension
    • IPF
    • Osteoarthritis
    • Psoriasis
    • Skin Disorders and Care
    • STDs
• Discover
  • Wellness Topics
    • Nutrition
    • Fitness
    • Skin Care
    • Sexual Health
    • Women’s Health
    • Mental Well-Being
    • Sleep
  • Product Reviews
    • Vitamins & Supplements
    • Sleep
    • Mental Health
    • Nutrition
    • At-Home Testing
    • CBD
    • Men’s Health
  • Original Series
    • Fresh Food Fast
    • Diagnosis Diaries
    • You’re Not Alone
    • Present Tense
  • Video Series
    • Youth in Focus
    • Healthy Harvest
    • No More Silence
    • Future of Health
• Plan
  • Health Challenges
    • Mindful Eating
    • Sugar Savvy
    • Move Your Body
    • Gut Health
    • Mood Foods
    • Align Your Spine
  • Find Care
    • Primary Care
    • Mental Health
    • OB-GYN
    • Dermatologists
    • Neurologists
    • Cardiologists
    • Orthopedists
  • Lifestyle Quizzes
    • Weight Management
    • Am I Depressed? A Quiz for Teens
    • Are You a Workaholic?
    • How Well Do You Sleep?
  • Tools & Resources
    • Health News
    • Find a Diet
    • Find Healthy Snacks
    • Drugs A-Z
    • Health A-Z
• Connect
  • • Breast Cancer
    • Inflammatory Bowel Disease
    • Psoriatic Arthritis
    • Migraine
    • Multiple Sclerosis
    • Psoriasis

Medically reviewed by Alan Carter, Pharm. D. — By Emily Cronkleton — Updated on February 15, 2023

Your doctor will give you the right dosage of vitamin B-12 supplement, especially if you will inject it. Taking too much can cause side effects like nausea, headache, dizziness, and in rarely, blood clots or cancer.

Everyone needs vitamin B-12, and most people get enough through their diet. However, it’s important to know what side effects occur when you take too much.

Vitamin B-12 is water-soluble and absorbed in the intestines. After it’s absorbed, it’s used to make DNA and red blood cells. Vitamin B-12 that isn’t being used is stored in the liver. But if you take supplements, you might ingest more than your body needs.

Oral vitamin B-12 is safe to take at recommended doses for healthy people.

Injectable vitamin B-12, which is used to treat significant deficiencies, can cause the following side effects:

• mild diarrhea
• itching
• skin rash
• headache
• dizziness
• nausea
• vomiting
• pulmonary edema and congestive heart failure early in treatment
• vein thrombosis
• sensation of swelling
• polycythemia vera (rare, slow growing blood cancer)

Vitamin B-12 can cause very rare but serious allergic reactions (anaphylaxis). This includes swelling of the face, tongue, and throat, and difficulty swallowing and breathing. If this occurs after you take vitamin B-12, call 911 or your local emergency services immediately.

Some agents are linked to reduced absorption or serum levels of vitamin B-12. You may need vitamin B-12 supplements if you take any of the following:

• colchicine
• metformin
• proton pump inhibitors
• vitamin C
• chloramphenicol
• h3 blockers
• aminosalicylic acid

Folic acid supplements may interfere with vitamin B-12. Be sure to tell your doctor if you take folic acid.

You may need to take vitamin B-12 separately from the above drugs and supplements — say, one in the morning and one at night — so you can get the full dose of vitamin B-12.

Don’t take vitamin B-12 supplements if you have sensitivities or allergies to vitamin B-12, cobalt, and any other ingredients. Vitamin B-12 is safe to take in recommended dosages if you’re pregnant or breastfeeding.

If you notice any adverse effects after you start taking vitamin B-12 supplements, you should discontinue use immediately. Seek medical attention if your symptoms get worse or are severe.

You can consult your doctor to establish an appropriate dose if it’s determined that you don’t get enough B-12 from food sources.

According to the National Institutes of Health, the recommended dietary amounts (RDAs) are as follows:

• 2.4 micrograms (mcg) daily for ages 14 years or older
• 2.6 mcg daily for pregnant women
• 2.8 mcg daily for breastfeeding women

If you’re over the age of 50, you should try to get your RDA by eating foods with B-12 or by taking a supplement containing 25 to 100 mcg of B-12.

Foods with vitamin B-12 include:

• eggs
• cheese
• fish
• shellfish
• liver
• kidney
• red meat

See your doctor if you have bothersome side effects that don’t go away once you stop taking the supplements. Avoid taking supplements if possible, and try to get B-12 from food sources.

If you develop any side effects from taking vitamin B-12, you can stop taking the supplement and the symptoms should subside.

After this, you’ll need to determine either an appropriate dose or how to get the vitamin B-12 you need from food sources. You can discuss this with your doctor.

Last medically reviewed on August 9, 2019

How we reviewed this article:

Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.

• Cyanocobalamin – cyanocobalamin injection. (2018).
  dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a66eb3c4-3e1d-4d49-b963-4fa2334cc9b6
• Vitamin B-12. (2017).
  mayoclinic.org/drugs-supplements-vitamin-b12/art-20363663
• Vitamin B12: Fact sheet for health professionals. (2018).
  ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/

Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available.

Current Version

Feb 15, 2023

Written By

Emily Cronkleton

Edited By

Frank Crooks

Aug 9, 2019

Medically Reviewed By

Alan Carter, PharmD

Share this article

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• Vitamin B12 Dosage: How Much Should You Take per Day?

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• Selenium Deficiency

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  Vitamin D is very important for your health, but it is possible to get too much. This article explores 6 signs and side effects of taking too much…

  READ MORE

Cyanocobalamin (Vitamin B12) – instructions for use, doses, side effects, reviews of the drug Cyanocobalamin (Vitamin B12) based on official instructions, approved by the manufacturer in 1998

Approval date: 07/31/1998

Contents

• Active substance
• ATX
• Pharmacological group
• Nosological classification (ICD-10)
• Composition and form of release
• pharmachologic effect
• pharmachologic effect
• Indications
• Contraindications
• Dosage and administration
• Side effects
• Interaction
• Precautionary measures
• Storage conditions
• Best before date
• Reviews

Active ingredient

Cyanocobalamin* (Cyanocobalamin*)

ATX

B03BA01 Cyanocobalamin

Pharmacological group

Stimulants of hematopoiesis

Vitamins and vitamin-like products

Nosological classification (ICD-10)

ICD-10 code list

• D50 Iron deficiency anemia
• D50. 0 Iron deficiency anemia secondary to blood loss (chronic)
• D51 Vitamin B12 deficiency anemia
• D52 Folate deficiency anemia
• D64 Other anemias
• E53 Deficiency of other B vitamins
• E53.8.0* Vitamin Bc deficiency
• E53. 8.1* Vitamin B12 deficiency
• G12.2 Motor neuron disease
• G35 Multiple sclerosis
• G50 Trigeminal nerve lesions
• G54.1 Lesions of the lumbosacral plexus
• G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
• G80 Cerebral palsy
• G95. 9 Disease of spinal cord, unspecified
• K73 Chronic hepatitis, not elsewhere classified
• K74 Fibrosis and cirrhosis of the liver
• M79.2 Neuralgia and neuritis, unspecified
• Q90 Down syndrome
• R68.8 Other specified general symptoms and signs

Composition and formulation

1 ml solution for injection contains cyanocobalamin (vitamin B ₁₂ ) 200 or 500 mcg; in ampoules of 1 ml, in a cardboard box 10 pcs.

Pharmacological action

Pharmacological action –

hematopoietic , stimulating cellular metabolism .

Participates in the transfer of methyl fragments, the formation of choline, methionine, creatine, nucleic acids, the maturation of erythrocytes, promotes the accumulation of compounds containing sulfhydryl groups in erythrocytes.

Participates in the transfer of methyl fragments, the formation of choline, methionine, creatine, nucleic acids, the maturation of erythrocytes, promotes the accumulation of compounds containing sulfhydryl groups in erythrocytes.

Indications

Anemia (Addison-Birmer, alimentary macrocytic, iron deficiency,
posthemorrhagic, aplastic, caused by toxic substances and drugs), cirrhosis of the liver,
hepatitis, myelosis, polyneuritis, sciatica, trigeminal neuralgia, amyotrophic lateral sclerosis, children
cerebral palsy, multiple sclerosis, Down’s disease, skin diseases, peripheral nerve injuries.

Contraindications

Thromboembolism, angina.

Dosage and administration

Information for healthcare professionals only.
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S/C, IM, IV and intralumbar.

Addison-Birmer anemia – 100-200 mcg every other day; with Addison-Birmer anemia with symptoms of funicular myelosis and with macrocytic anemia with disorders of the nervous system – 500 mcg or more per injection (daily for the first week, and then with intervals between injections of up to 5-7 days). Simultaneously appoint folic acid. In the period of remission, in the absence of funicular myelosis phenomena, 100 mcg is administered for maintenance therapy 2 times a month, and in the presence of neurological phenomena, 200-400 mcg 2-4 times a month.

For iron deficiency and posthemorrhagic anemia – 30-100 mcg 2-3 times a week; with aplastic anemia (especially in children) – 100 mcg until the onset of clinical and hematological improvement; with alimentary anemia in children at an early age and in premature babies – 30 mcg / day for 15 days.

In diseases of the central nervous system and neurological diseases with pain syndrome, it is administered in increasing doses from 200 to 500 mcg per injection, and when the condition improves, 100 mcg/day; course – up to 2 weeks.

In traumatic lesions of the peripheral nerves – 200-400 mcg every other day for 40-45 days.

For hepatitis and liver cirrhosis, 30–60 mcg per day or 100 mcg every other day for 25–40 days.

With dystrophies in young children, Down’s disease and cerebral palsy – 15-30 mcg every other day.

In case of funicular myelosis, amyotrophic lateral sclerosis, multiple sclerosis, sometimes 15-30 mcg is injected into the spinal canal (gradually increasing the dose to 200-250 mcg).

Side effects

Excitation, pain in the heart, tachycardia, allergic reactions.

Interactions

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Incompatible (in one syringe) with thiamine bromide, riboflavin.

Precautions

In angina pectoris, use with caution and in lower doses.

Storage conditions

In a place protected from light.

Keep out of reach of children.

Expiry date

2 years.

Do not use after the expiry date which is stated on the pack.

tablets, instant, 5000 mcg

0.008 ‰

Analogs

Choice of description

instant tablets

5000 mcg

injection

0.2 mg/ml

All forms of release, dosages, registration certificates, drug manufacturers, drug characteristics

Product description Vitamin B12 (solution for injection, 0.2 mg/ml) based on the official instructions, approved by the manufacturer in 1998

Date approved: 07/31/1998

Contents

• Active substance
• ATX
• Pharmacological group
• Composition and form of release
• Dosage and administration
• Storage conditions
• Best before date
• Reviews

Active ingredient

Cyanocobalamin* (Cyanocobalamin*)

ATX

B03BA01 Cyanocobalamin

Pharmacological group

Stimulants of hematopoiesis

Vitamins and vitamin-like products

Composition and form of release

1 ampoule with 1 ml solution for injection contains cyanocobalamin 200 or 500 mcg; in a box of 10 pcs. , complete with an ampoule knife.

Dosage and administration

Information for healthcare professionals only.
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S/C, IM, IV and intralumbar. For Addison-Birmer anemia (in combination with folic acid)
– 100-200 mcg once a day, for 2 days; with Addison-Birmer anemia with symptoms
funicular myelosis and macrocytic anemia with disorders of the nervous system – 500 mcg and
more per injection (in the first week daily, and then at intervals between injections up to 5-7 days). During
remissions – 100 mcg 2 times a month (maintenance therapy), in the presence of neurological phenomena
(funicular myelosis) – 200-400 mcg 2-4 times a month. With iron deficiency and
posthemorrhagic anemia – 30-100 mcg 2-3 times a week; with aplastic anemia
(especially in children) – 100 mcg until the onset of clinical and hematological improvement; with alimentary
anemia in children at an early age and in premature babies – 30 mcg / day for 15 days.