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What does penicillin vk 500mg treat. Penicillin VK 500mg: Uses, Dosage, Side Effects, and Interactions

What conditions does penicillin VK 500mg treat. How should penicillin VK 500mg be taken. What are the common side effects of penicillin VK 500mg. How does penicillin VK 500mg interact with other medications.

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Understanding Penicillin VK 500mg: A Powerful Antibiotic

Penicillin VK 500mg is a potent antibiotic medication used to treat various bacterial infections. As a member of the penicillin class of antibiotics, it plays a crucial role in combating harmful bacteria that cause illness. This article delves into the uses, dosage, side effects, and interactions of penicillin VK 500mg, providing valuable information for those prescribed this medication.

What Infections Does Penicillin VK 500mg Treat?

Penicillin VK 500mg is effective against a range of bacterial infections. These include:

  • Streptococcal upper respiratory tract infections
  • Scarlet fever
  • Erysipelas infections
  • Pneumococcal upper respiratory infections
  • Staphylococcal skin and soft tissue infections
  • Fusospirochetosis (infection of the oropharynx or middle part of the throat)

Additionally, penicillin VK 500mg is used in the prevention of rheumatic fever and chorea. It’s important to note that this antibiotic is ineffective against viral infections such as the common cold.

Dosage and Administration of Penicillin VK 500mg

The dosage of penicillin VK 500mg varies depending on the type and severity of the infection, as well as the patient’s age and overall health. For adults and children 12 years and older, typical dosages include:

  • For streptococcal infections: 125-250 mg taken every 6-8 hours for 10 days
  • For pneumococcal upper respiratory infections: 250-500 mg taken every 6 hours until the fever has subsided for at least 2 days

Is it safe for children under 12 to take penicillin VK 500mg? The safety and efficacy of this medication have not been confirmed for children under 12 years of age. Always consult a pediatrician for appropriate dosing in younger children.

How Does Penicillin VK 500mg Work?

Penicillin VK 500mg belongs to the antibiotic class of medications. Its mechanism of action involves inhibiting bacterial cell wall synthesis, which ultimately leads to the death of the bacteria. By stopping the multiplication of bacteria, penicillin VK 500mg effectively treats the infection and alleviates symptoms.

The Science Behind Penicillin’s Effectiveness

Penicillin VK 500mg targets the peptidoglycan layer of bacterial cell walls. This layer is crucial for maintaining the structural integrity of the bacteria. By interfering with the formation of this layer, penicillin VK 500mg causes the bacterial cells to become unstable and eventually burst, leading to their destruction.

Common Side Effects of Penicillin VK 500mg

While penicillin VK 500mg is generally well-tolerated, some patients may experience side effects. Common side effects include:

  • Nausea
  • Vomiting
  • Stomach upset
  • Diarrhea
  • Black hairy tongue

These side effects are usually mild and may resolve on their own within a few days to a couple of weeks. However, if they persist or worsen, it’s important to consult your healthcare provider.

Recognizing Serious Side Effects

While rare, serious side effects can occur with penicillin VK 500mg. These may include:

  • Allergic reactions (skin rash, flu-like symptoms, swelling of the throat, tongue, or mouth)
  • Severe diarrhea (bloody or watery, accompanied by fever and stomach cramps)

If you experience any of these serious side effects, seek immediate medical attention.

Interactions with Other Medications

Penicillin VK 500mg can interact with other medications, potentially altering their effectiveness or increasing the risk of side effects. Some potential interactions include:

  • Oral contraceptives: Penicillin may reduce the effectiveness of birth control pills
  • Probenecid: This medication can increase penicillin levels in the body
  • Methotrexate: Penicillin may increase the toxicity of this drug

To avoid potential interactions, always inform your healthcare provider about all medications, vitamins, and supplements you’re taking before starting penicillin VK 500mg.

Precautions and Considerations for Penicillin VK 500mg Use

Before taking penicillin VK 500mg, it’s crucial to consider certain factors to ensure safe and effective treatment:

Allergies and Sensitivities

Do you have a history of allergic reactions to penicillin or other antibiotics? Inform your healthcare provider about any known allergies, especially to antibiotics in the penicillin family. Cross-reactivity between different types of penicillins is common, and allergic reactions can be severe.

Pregnancy and Breastfeeding

Is penicillin VK 500mg safe during pregnancy or while breastfeeding? While penicillin is generally considered safe for use during pregnancy and breastfeeding, always consult your healthcare provider to weigh the potential risks and benefits in your specific situation.

Existing Medical Conditions

Certain medical conditions may affect the use of penicillin VK 500mg. These include:

  • Kidney disease
  • Asthma
  • Bleeding disorders
  • Mononucleosis

Discuss your medical history with your healthcare provider to ensure penicillin VK 500mg is appropriate for you.

Proper Storage and Disposal of Penicillin VK 500mg

To maintain the effectiveness and safety of penicillin VK 500mg, proper storage and disposal are essential:

Storage Guidelines

  • Store at room temperature, away from heat, moisture, and direct light
  • Keep the medication in its original container
  • Keep out of reach of children and pets

Disposal Instructions

How should you dispose of unused or expired penicillin VK 500mg? Do not flush medications down the toilet or pour them down the drain unless instructed to do so. Instead, use a medicine take-back program or follow local guidelines for safe disposal.

Monitoring Your Progress on Penicillin VK 500mg

While taking penicillin VK 500mg, it’s important to monitor your progress and communicate with your healthcare provider:

Follow-up Appointments

Attend all scheduled follow-up appointments with your healthcare provider. These visits allow for assessment of your progress and any necessary adjustments to your treatment plan.

Tracking Symptoms

Keep a record of your symptoms and any side effects you experience. This information can be valuable for your healthcare provider in evaluating the effectiveness of the treatment.

Completing the Full Course

Why is it crucial to complete the full course of penicillin VK 500mg? Even if you start feeling better before finishing the prescribed course, it’s essential to take all the medication as directed. Stopping early can lead to the development of antibiotic-resistant bacteria.

Understanding Antibiotic Resistance and Penicillin VK 500mg

Antibiotic resistance is a growing concern in healthcare. To help prevent the development of resistant bacteria:

  • Only use penicillin VK 500mg when prescribed by a healthcare provider
  • Take the medication exactly as directed
  • Do not share your antibiotics with others
  • Do not save leftover antibiotics for future use

By using antibiotics responsibly, we can help preserve their effectiveness for future generations.

Alternative Treatments and Complementary Therapies

While penicillin VK 500mg is often the primary treatment for certain bacterial infections, there may be alternative or complementary approaches to consider:

Alternative Antibiotics

In cases of penicillin allergy or resistance, your healthcare provider may prescribe alternative antibiotics such as:

  • Macrolides (e.g., erythromycin, azithromycin)
  • Cephalosporins
  • Fluoroquinolones

Supportive Therapies

In addition to antibiotic treatment, supportive therapies can help manage symptoms and promote recovery:

  • Rest and adequate hydration
  • Over-the-counter pain relievers and fever reducers
  • Throat lozenges or gargling with salt water for sore throat
  • Humidifiers to ease respiratory symptoms

Probiotics

Can probiotics help prevent antibiotic-associated diarrhea? Some studies suggest that taking probiotics during and after antibiotic treatment may help reduce the risk of antibiotic-associated diarrhea. However, consult your healthcare provider before adding any supplements to your regimen.

The Future of Antibiotic Treatment

As antibiotic resistance continues to be a global health concern, researchers are exploring new approaches to treating bacterial infections:

Novel Antibiotic Development

Scientists are working on developing new classes of antibiotics that can overcome existing resistance mechanisms. These efforts aim to provide alternative treatment options for infections that no longer respond to current antibiotics.

Bacteriophage Therapy

Bacteriophages, viruses that infect and kill bacteria, are being studied as a potential alternative or complementary treatment to traditional antibiotics. This approach shows promise in targeting specific bacterial strains while minimizing damage to beneficial bacteria.

Personalized Medicine

Advances in genetic testing and diagnostic technologies may lead to more personalized antibiotic treatments. This approach could help healthcare providers select the most effective antibiotic for each patient based on their individual characteristics and the specific bacteria causing the infection.

Conclusion: The Importance of Responsible Antibiotic Use

Penicillin VK 500mg remains a valuable tool in the fight against bacterial infections. By understanding its uses, proper administration, potential side effects, and interactions, patients can make informed decisions about their treatment. Remember to always follow your healthcare provider’s instructions, complete the full course of antibiotics, and report any concerns or side effects promptly. With responsible use, we can help ensure the continued effectiveness of antibiotics like penicillin VK 500mg in treating bacterial infections and protecting public health.

Penicillin V | Side Effects, Dosage, Uses, and More

Highlights for penicillin V

  1. Penicillin V oral tablet is only available as a generic drug.
  2. Penicillin V also comes as an oral solution.
  3. Penicillin V oral tablet is used to treat certain infections caused by bacteria. It won’t work for infections caused by viruses, such as the common cold.

Penicillin V is a prescription drug that comes as an oral tablet and an oral solution.

Penicillin V oral tablet is only available as a generic drug.

Why it’s used

Penicillin V oral tablet is used to treat certain infections caused by bacteria. It won’t work to treat infections caused by viruses, such as the common cold. Bacterial infections this drug is used to treat include:

  • streptococcal upper respiratory tract infections, scarlet fever, and erysipelas infections
  • pneumococcal upper respiratory infections
  • staphylococcal skin and soft tissue infections
  • fusospirochetosis (infection of the oropharynx or middle part of the throat)
  • prevention of rheumatic fever and chorea

This drug may be used as part of a combination therapy. This means you may need to take it with other medications.

How it works

Penicillin V belongs to a class of drugs called antibiotics. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

Penicillin V works by stopping the bacteria from multiplying. This kills off the bacteria that are causing your infection.

Penicillin V oral tablet doesn’t cause drowsiness. However, it may cause other side effects.

More common side effects

The more common side effects of penicillin V can include:

  • nausea
  • vomiting
  • stomach upset
  • diarrhea
  • black hairy tongue

If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.

Serious side effects

Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

  • Allergic reaction. Symptoms can include:
    • skin rash with or without blisters
    • flu-like symptoms, such as a fever, feeling ill, or joint pain
    • swelling of your throat, tongue, or mouth
  • Diarrhea. Symptoms include:
    • bloody or watery diarrhea with or without stomach cramps and a fever

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.

Penicillin V oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

To help prevent interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

This dosage information is for penicillin V oral tablet. All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:

  • your age
  • the condition being treated
  • the severity of your condition
  • other medical conditions you have
  • how you react to the first dose

Forms and strengths

Generic: Penicillin V

  • Form: Oral tablet
  • Strengths: 250 mg, 500 mg

Dosage for streptococcal infection

Adult dosage (ages 18 years and older)

  • Typical dosage: 125–250 mg taken every 6–8 hours for 10 days.

Child dosage (ages 12–17 years)

  • Typical dosage: 125–250 mg taken every 6–8 hours for 10 days.

Child dosage (ages 0–11 years)

It hasn’t been confirmed that this drug is safe and effective for use in people younger than 12 years.

Dosage for pneumococcal upper respiratory infection

Adult dosage (ages 18 years and older)

  • Typical dosage: 250–500 mg taken every 6 hours until you no longer have a fever for at least 2 days.

Child dosage (ages 12–17 years)

  • Typical dosage: 250–500 mg taken every 6 hours until you no longer have a fever for at least 2 days.

Child dosage (ages 0–11 years)

It hasn’t been confirmed that this drug is safe and effective for use in people younger than 12 years.

Dosage for staphylococcal skin or soft tissue infection

Adult dosage (ages 18 years and older)

  • Typical dosage: 250–500 mg taken every 6–8 hours.

Child dosage (ages 12–17 years)

  • Typical dosage: 250–500 mg taken every 6–8 hours.

Child dosage (ages 0–11 years)

It hasn’t been confirmed that this drug is safe and effective for use in people younger than 12 years.

Dosage for prevention of rheumatic fever or chorea or both

Adult dosage (ages 18 years and older)

  • Typical dosage: 125–250 mg taken two times per day.

Child dosage (ages 12–17 years)

  • Typical dosage: 125–250 mg taken two times per day.

Child dosage (ages 0–11 years)

It hasn’t been confirmed that this drug is safe and effective for use in people younger than 12 years.

Dosage for fusospirochetosis (oropharynx infection)

Adult dosage (ages 18 years and older)

  • Typical dosage: 250–500 mg taken every 6–8 hours.

Child dosage (ages 12–17 years)

  • Typical dosage: 250–500 mg taken every 6–8 hours.

Child dosage (ages 0–11 years)

It hasn’t been confirmed that this drug is safe and effective for use in people younger than 12 years.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always speak with your doctor or pharmacist about dosages that are right for you.

Penicillin V oral tablet is used for short-term treatment. It comes with serious risks if you don’t take it as prescribed.

If you stop taking the drug suddenly or don’t take it at all: Your infection may not get better or may get worse. Even if you’re starting to feel better, you should still finish all of your medication.

If you miss doses or don’t take the drug on schedule: Your medication may not work as well or may stop working completely. For this drug to work well, a certain amount needs to be in your body at all times.

If you take too much: You could have dangerous levels of this drug in your body. Symptoms of an overdose of this drug can include:

  • Diarrhea
  • Nausea
  • Oral infection. Symptoms can include:
    • creamy white lesions that look like cottage cheese
    • cotton mouth (dry mouth)
  • Vomiting
  • Blackened tongue

If you think you’ve taken too much of this drug, call your doctor or seek guidance from the American Association of Poison Control Centers at 1-800-222-1222 or through their online tool. But if your symptoms are severe, call 911 or go to the nearest emergency room right away.

What to do if you miss a dose: Take your dose as soon as you remember. But if you remember just a few hours before your next scheduled dose, take only one dose. Never try to catch up by taking two doses at once. This could result in dangerous side effects.

How to tell if the drug is working: Your symptoms and your infection should get better.

As with all medications, the costs of penicillin V can vary.

Keep these considerations in mind if your doctor prescribes penicillin V oral tablet for you.

General

Do not take this drug with food. Take it on an empty stomach, at least 1 hour before eating or 2 hours after eating.

You can cut or crush the tablet.

Storage

  • Store this drug at room temperature. Keep it between 68°F and 77°F (15°C and 30°C).
  • Keep the container tightly closed.
  • Don’t store this medication in moist or damp areas, such as bathrooms.

Refills

A prescription for this medication is refillable. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.

Travel

When traveling with your medication:

  • Always carry your medication with you. When flying, never put it into a checked bag. Keep it in your carry-on bag.
  • Don’t worry about airport X-ray machines. They can’t hurt your medication.
  • You may need to show airport staff the pharmacy label for your medication. Always carry the original prescription-labeled container with you.
  • Don’t put this medication in your car’s glove compartment or leave it in the car. Be sure to avoid doing this when the weather is very hot or very cold.

Clinical monitoring

Your doctor may do blood tests to check how well your kidneys are working. If your kidneys aren’t working well, your doctor may lower your dose of this drug.

There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other drug options that may work for you.

  • Serious allergic reaction warning: This drug can cause a severe allergic reaction. Symptoms include a skin rash with or without blisters, flu-like symptoms (such as a fever, feeling ill, or joint pain), or swelling of your throat, tongue, or mouth. If you have an allergic reaction, call your doctor or local poison control center right away. If your symptoms are severe, call 911 or go to the nearest emergency room. Don’t take this drug again if you’ve ever had an allergic reaction to it.
  • Severe diarrhea warning: This drug may cause diarrhea during and after your treatment with it. This diarrhea can be caused by an infection in your intestine called Clostridium difficile. Call your doctor right away if you have bloody or watery diarrhea with or without stomach cramps and a fever while you’re taking this drug.
  • Prescription completion warning: It’s important you finish all of your penicillin V prescription even if you’re feeling better. If you skip doses or don’t complete the full course of treatment, this drug won’t work as well. Also, the bacteria causing your infection may become resistant to treatment. Resistance means that it won’t respond to penicillin V or other antibiotics in the future.

Allergy warning

Penicillin V can cause a severe allergic reaction. Symptoms can include:

  • skin rash with or without blisters
  • flu-like symptoms, such as a fever, feeling ill, or joint pain
  • swelling of your throat, tongue, or mouth

If you have an allergic reaction, call your doctor or local poison control center right away. If your symptoms are severe, call 911 or go to the nearest emergency room.

Don’t take this drug again if you’ve ever had an allergic reaction to it or any other type of penicillin. Taking it again could be fatal (cause death).

If you have severe allergies, you have a higher risk of developing a severe allergic reaction to penicillin. This type of allergic reaction is called anaphylaxis. Symptoms can include throat swelling, trouble swallowing, wheezing, and trouble breathing.

Warnings for people with certain health conditions

For people with asthma: If you have asthma, you have a higher risk of developing a severe allergic reaction to penicillin. This type of allergic reaction is called anaphylaxis. Symptoms can include throat swelling, trouble swallowing, wheezing, and trouble breathing.

For people with kidney problems: If you have kidney problems or a history of kidney disease, you may not be able to clear this drug from your body well. This may increase the levels of penicillin V in your body and cause more side effects.

Warnings for other groups

For pregnant women: The Food and Drug Administration (FDA) hasn’t assigned a pregnancy category to penicillin V. It is not yet known if penicillin V is safe and effective for use in pregnant women. Tell your doctor if you’re pregnant or plan to become pregnant. Penicillin V should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

For women who are breastfeeding: Penicillin V may pass into breast milk and may cause side effects in a child who is breastfed. Talk to your doctor if you breastfeed your child. You may need to decide whether to stop breastfeeding or stop taking this medication.

For seniors: The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects.

For children: This drug hasn’t been studied in children. It shouldn’t be used in people younger than 12 years of age.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

Penicillin VK Oral Tablet 250 mg, 500 mg – Health Information Library

For treating bacterial infection.

Generic Name: Penicillin VK

Instructions

This medicine may be taken with or without food.

Keep the medicine at room temperature. Avoid heat and direct light.

If you forget to take a dose on time, take it as soon as you remember. If it is almost time for the next dose, do not take the missed dose. Return to your normal schedule. Do not take 2 doses at one time.

Tell your doctor and pharmacist about all your medicines. Include prescription and over-the-counter medicines, vitamins, and herbal medicines.

Tell your doctor if symptoms do not get better or if they get worse.

Keep using this medicine for the full number of days that it is prescribed. Do not stop the medicine even if you start to feel better.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Do not use the medication any more than instructed.

Please tell your doctor if you have moderate to severe diarrhea while on this medicine. Do not treat the diarrhea with over-the-counter diarrhea medicine.

Tell the doctor or pharmacist if you are pregnant, planning to be pregnant, or breastfeeding.

Do not start or stop any other medicines without first speaking to your doctor or pharmacist.

Do not share this medicine with anyone who has not been prescribed this medicine.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • diarrhea
  • nausea and vomiting
  • stomach upset or abdominal pain
  • yeast infection of mouth
  • vaginal itching or yeast infection

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • bleeding or bruising
  • severe, watery or bloody diarrhea
  • joint or muscle pain
  • unusual or unexplained tiredness or weakness

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.

IMPORTANT NOTE: This document tells you briefly how to take your medicine, but it does not tell you all there is to know about it. Your doctor or pharmacist may give you other documents about your medicine. Please talk to them if you have any questions. Always follow their advice.

There is a more complete description of this medicine available in English. Scan this code on your smartphone or tablet or use the web address below. You can also ask your pharmacist for a printout. If you have any questions, please ask your pharmacist.

The display and use of this drug information is subject to Terms of Use.

https://api.meducation.com/V2.0/fdbpem/2050

Copyright(c) 2023 First Databank, Inc.

Selected from data included with permission and copyright by First DataBank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

Conditions of Use: The information in this database is intended to supplement, not substitute for the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express Terms of Use.

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Health Information Library

Penicillin G sodium salt instructions for use: indications, contraindications, side effects – description Penicillin G sodium salt Powder for solution for injection (4179)

💊 Composition of the drug Penicillin G Sodium salt

✅ Use of the drug Penicillin G Sodium salt

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⚠️ The state registration of this drug has been canceled

Description of the active ingredients of the preparation

Penicillin G Sodium Salt
(Penicillin G sodium salt)

The scientific information provided is general and cannot be used to make decisions.
decisions about the use of a particular drug.

Renewal date: 2020.03.18

Marketing authorization holder:

BIOCHEMIE GmbH
(Austria)

ATX code:

J01CE01

(Benzylpenicillin)

Active substance:
benzylpenicillin
(benzylpenicillin)

Rec.INN

registered by WHO

Dosage form

Penicillin G Sodium Salt

Powder for preparation. solution for injections. 1 million units: fl. 100 pieces.

reg. No.: P N012660/01-2001
dated 07.02.01
– Cancellation of the State. registration

Release form, packaging and composition
drug Penicillin G Sodium salt

Vials (100) – cardboard boxes.

Clinical and pharmacological group:

Antibiotic of the penicillin group, destroyed by penicillinase

Pharmaco-therapeutic group:

Antibiotic, penicillin

Pharmacological action

Antibiotic of the biosynthetic penicillin group. It has a bactericidal effect by inhibiting the synthesis of the cell wall of microorganisms.

Active against Gram-positive bacteria: Staphylococcus spp., Streptococcus spp. (including Streptococcus pneumoniae), Corynebacterium diphtheriae, Bacillus anthracis; gram-negative bacteria: Neisseria gonorrhoeae, Neisseria meningitidis; anaerobic spore-forming rods; as well as Actinomyces spp. , Spirochaetaceae.

Penicillinase-producing strains of Staphylococcus spp. are resistant to benzylpenicillin. Decomposes in an acidic environment.

Novocaine salt of benzylpenicillin compared to potassium and sodium salts is characterized by a longer duration of action.

Pharmacokinetics

After intramuscular administration, it is rapidly absorbed from the injection site. Widely distributed in tissues and body fluids. Benzylpenicillin penetrates well through the placental barrier, the BBB during inflammation of the meninges.

T 1/2 – 30 min. Excreted with urine.

Indications of the active substances of the drug

Penicillin G Sodium Salt

Treatment of diseases caused by microorganisms sensitive to benzylpenicillin: lobar and focal pneumonia, pleural empyema, sepsis, septicemia, pyemia, acute and subacute septic endocarditis, meningitis, acute and chronic osteomyelitis, urinary and biliary tract infections, tonsillitis, purulent skin infections, soft tissues and mucous membranes, erysipelas, diphtheria, scarlet fever, anthrax, actinomycosis, treatment of pyoinflammatory diseases in obstetric and gynecological practice, ENT diseases, eye diseases, gonorrhea, blennorrhea, syphilis.

Open list of ICD-10 codes

A22 Anthrax
A36 Diphtheria
A38 Scarlet fever
A40 Streptococcal sepsis
A41 Other sepsis
A42 Actinomycosis
A46 erysipelas
A50 Congenital syphilis
A51 Early syphilis
A52 Late syphilis
A54 Gonococcal infection
A54. 3 Gonococcal eye infection
G00 Bacterial meningitis, not elsewhere classified
h20 Conjunctivitis
h25.0 Sclerite
h25.1 Episcleritis
h26 Keratitis
h30 Iridocyclitis
H66 Purulent and unspecified otitis media
I33 Acute and subacute endocarditis
J01 Acute sinusitis
J02 Acute pharyngitis
J03 Acute tonsillitis
J04 Acute laryngitis and tracheitis
J15 Bacterial pneumonia, not elsewhere classified
J20 Acute bronchitis
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
J32 Chronic sinusitis
J35. 0 Chronic tonsillitis
J37 Chronic laryngitis and laryngotracheitis
J42 Chronic bronchitis, unspecified
J86 Pyothorax (pleural empyema)
K81.0 Acute cholecystitis
K81.1 Chronic cholecystitis
K83.0 Cholangitis
L01 Impetigo
L02 Skin abscess, furuncle and carbuncle
L03 Phlegmon
L08. 0 Pyoderma
L08.8 Other specified local skin and subcutaneous tissue infections
M86 Osteomyelitis
N10 Acute tubulointerstitial nephritis (acute pyelonephritis)
N11 Chronic tubulointerstitial nephritis (chronic pyelonephritis)
N30 Cystitis
N34 Urethritis and urethral syndrome
N41 Inflammatory diseases of the prostate
N70 Salpingitis and oophoritis
N71 Inflammatory disease of the uterus, except for the cervix (including endometritis, myometritis, metritis, pyometra, uterine abscess)
N72 Inflammatory disease of the cervix (including cervicitis, endocervicitis, exocervicitis)
N73. 5 Female pelvic peritonitis, unspecified
T79.3 Post-traumatic wound infection, not elsewhere classified

Dosing regimen

The route of administration and dosing regimen of a particular drug depends on its form of release and other factors. The optimal dosage regimen is determined by the doctor. Compliance of the dosage form of a particular drug with indications for use and dosing regimen should be strictly observed.

Individual. Enter in / m, in / in, s / c, endolumbally.

When administered intramuscularly and intramuscularly to adults, the daily dose varies from 250,000 to 60 million units. The daily dose for children under the age of 1 year is 50,000-100,000 IU / kg, over 1 year – 50,000 IU / kg; if necessary, the daily dose can be increased to 200,000-300,000 IU / kg, according to vital indications – up to 500,000 IU / kg. Multiplicity of introduction 4-6 times / day.

Endolumbally administered depending on the disease and the severity of the course, adults – 5000-10,000 IU, children – 2000-5000 IU. The drug is diluted in sterile water for injection or in 0.9% sodium chloride solution at the rate of 1 thousand units / ml. Before injection (depending on the level of intracranial pressure), 5-10 ml of CSF is removed and added to the antibiotic solution in equal proportions.

SC benzylpenicillin is used for chipping infiltrates (100,000-200,000 IU in 1 ml of 0.25%-0.5% novocaine solution).

Benzylpenicillin potassium salt is used only in / m and s / c, in the same doses as benzylpenicillin sodium salt.

Benzylpenicillin novocaine salt is used only in / m. The average therapeutic dose for adults: single – 300,000 IU, daily – 600,000 IU. Children under the age of 1 year – 50,000-100,000 U / kg / day, over 1 year – 50,000 U / kg / day. Multiplicity of introduction 3-4 times / day.

The duration of treatment with benzylpenicillin, depending on the form and severity of the course of the disease, can range from 7-10 days to 2 months or more.

Side effects

From the digestive system: diarrhea, nausea, vomiting.

Effects due to chemotherapeutic action: vaginal candidiasis, oral candidiasis.

From the side of the central nervous system: when using benzylpenicillin in high doses, especially with endolumbar administration, neurotoxic reactions may develop: nausea, vomiting, increased reflex excitability, symptoms of meningism, convulsions, coma.

Allergic reactions: fever, urticaria, skin rash, rash on mucous membranes, joint pain, eosinophilia, angioedema. Cases of anaphylactic shock with a fatal outcome are described.

Contraindications for use

Hypersensitivity to benzylpenicillin and other drugs from the group of penicillins and cephalosporins. Endolumbar administration is contraindicated in patients suffering from epilepsy.

Use during pregnancy and lactation

Use during pregnancy is possible only if the expected benefit to the mother outweighs the potential risk to the fetus.

If necessary, use during lactation should decide on the termination of breastfeeding.

Use in impaired renal function

Use with caution in patients with impaired renal function.

Use in children

May be used in children if indicated.

Special instructions

Use with caution in patients with impaired renal function, with heart failure, a predisposition to allergic reactions (especially with drug allergies), with hypersensitivity to cephalosporins (due to the possibility of cross-allergy).

If there is no effect after 3-5 days after the start of the application, it is necessary to switch to the use of other antibiotics or combination therapy.

In connection with the possibility of developing fungal superinfection, it is advisable to prescribe antifungal drugs during treatment with benzylpenicillin.

It must be taken into account that the use of benzylpenicillin in subtherapeutic doses or early termination of treatment often leads to the emergence of resistant strains of pathogens.

Drug interactions

Probenecid reduces the tubular secretion of benzylpenicillin, resulting in an increase in the concentration of the latter in the blood plasma, increasing the half-life.

When used simultaneously with antibiotics that have a bacteriostatic effect (tetracycline), the bactericidal effect of benzylpenicillin decreases.

Keep

If you want to place a link to the description of this drug – use this code

Penicillin G Sodium salt . Description of the drug in the reference book Vidal.

Penicillin-VK Solution – instructions for use, dosage, composition, analogues, side effects / Pillintrip

Page reviewed by pharmacist Oleinik Elizaveta Ivanovna Last updated 1969-12-31

Top 20 drugs with the same ingredients:

Penicillin V PotasiumPenicillin V PotassiumPc Pen VKPenicillin VPenicillin-VK SolutionPen-Vee KV-Cillin K

Drug name

Description Name of the drug Penicillin-VK Solution is an automatic translation from the original language.
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Penicillin-VK Solution

Therapeutic indications

Description Therapeutic indications Penicillin-VK Solution is an automatic translation from the original language.
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Indication is a term used to list a condition or symptom or illness for which a drug is prescribed or used by a patient. For example, acetaminophen or paracetamol is used by a patient for a fever, or a doctor prescribes it for a headache or body aches. Currently, fever, headache and body aches are signs of paracetamol. The patient must be aware of the indications of the drugs used for general conditions because they can be taken over the counter in the sense of a pharmacy without a doctor’s prescription.

Penicillin-VC solution tablets and penicillin-VC oral solution are indicated for the treatment of mild to moderate infections caused by penicillin G-susceptible organisms. Therapy should be guided by bacteriological studies (including sensitivity tests) and clinical response.

NOTE: Severe pneumonia, empyema, bacteremia, pericarditis, meningitis, and arthritis should not be treated with penicillin-VC solution during the acute phase. The indicated surgical procedures must be performed.

The following infections usually respond to an adequate dose of penicillin-VC solution.

Streptococcal infections (without bacteremia). Mild to moderate upper respiratory tract infections, scarlet fever and mild erysipelas.

NOTE. Streptococci in groups A, C, G, H, L and M are very sensitive to penicillin. Other groups, including group D (Enterococcus), are resistant.

Pneumococcal infections. Mild or moderately severe respiratory tract infections.

Staphylococcal infections – penicillin G-sensitive. Mild skin and soft tissue infections.

NOTE. Reports indicate an increase in penicillin G-resistant strains of staphylococci, highlighting the need for culture and susceptibility studies in the treatment of suspected staph infections.

Fusospirochetosis (Gingivitis and Vincent’s Pharyngitis) – Mild to moderate oropharyngeal infections usually respond to oral penicillin therapy.

NOTE. Necessary dental care should be provided for infections associated with gum tissue.

Medical conditions in which oral penicillin therapy is indicated as prophylaxis: For the prevention of relapse after rheumatic fever and/or chorea: prophylaxis with oral penicillin on an ongoing basis has proven effective in preventing relapse of these conditions.

Although no controlled studies of clinical efficacy have been conducted, Penicillin-VC Solution has been proposed by the American Heart Association and the American Dental Association for use as an oral regimen for the prevention of bacterial endocarditis in patients with congenital heart disease or rheumatic or other acquired valvular heart disease in undergoing dental procedures and surgeries. upper respiratory procedures.1

Oral penicillin should not be used in patients at particularly high risk of developing endocarditis (eg, those with prosthetic heart valves or surgically constructed systemic pulmonary bypasses). Penicillin-VK solution should not be used as adjunctive prophylaxis for genitourinary devices or surgery, lower gastrointestinal surgery, sigmoidoscopy and childbirth. Since it may happen that penicillin-resistant alpha-hemolytic streptococci may be detected when patients receive continuous oral penicillin for secondary prevention of rheumatic fever, prophylactic agents other than penicillin may be selected for these patients and given in addition to their prevention regimen for continuous rheumatic fever.

NOTE. When choosing antibiotics for the prevention of bacterial endocarditis, the physician or dentist should read the full joint statement of the American Heart Association and the American Dental Association

Reduce the development of drug-resistant bacteria and maintain the effectiveness of Penicillin-VK Solution Tablets, Penicillin-VK Oral Solution, and other antibacterial drugs, Penicillin-VB solution tablets and Penicillin-VB solution for oral solution should only be used to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered when selecting or changing antibiotic therapy. In the absence of such data, local epidemiology and patterns of susceptibility may contribute to the empirical choice of therapy.

Penicillin-VK solution is a slow antibiotic that fights bacteria in your body.

Penicillin-VC solution is used to treat many different types of infections, including strep and staph infections, pneumonia, rheumatic fever, and infections that affect the mouth or throat.

Penicillin-VC solution is also used to prevent heart valve infections in people with certain heart conditions who need dental work or surgery.

Penicillin-VC solution may also be used for purposes not listed in this medication guide.

Dosage and Administration

Description Dosage and Administration Penicillin-VK Solution is an automatic translation from the original language.
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The dosage of penicillin-VB solution tablets and penicillin-VB solution for oral solution should be determined according to the susceptibility of pathogens and the severity of the infection and adjusted according to the clinical response of the patient.

The usual dosage recommendations for adults and children 12 years of age and older are: 000 units) every 6-8 hours for 10 days.

Mild to moderate pneumococcal infections of the respiratory tract, including otitis media: 250 to 500 mg (400,000 to 800,000 units) every 6 hours until the patient has afebrated for at least 2 days.

Staphylococcal infections – mild skin and soft tissue infections (necessary culture and susceptibility tests): 250 to 500 mg (400,000 to 800,000 units) every 6 to 8 hours.

Fusospirochetosis (Vincent’s infection) of the oropharynx. Mild to moderate infections: 250 to 500 mg (400,000 to 800,000 units) every 6 to 8 hours.

For the prevention of relapse after rheumatic fever and/or chorea: 125 to 250 mg (200,000 to 400,000 units) twice a day on a continuous basis.

For the prevention of bacterial endocarditis1 in patients with congenital heart disease or rheumatic or other acquired valvular heart disease while undergoing dental or upper airway surgery: 2 grams of penicillin-VC solution (1 gram for children under 60 pounds). ) 1 hour before the procedure, followed by 1 gram (500 mg for children under 60 lbs.) 6 hours later.

Mixing Directions

Oral Solution

Do not add water until you refuse. When dosing, tap the bottle until all the powder starts loose, slowly add the total amount of water to reconstitute. After the bottle is partially filled, replace the cap and shake vigorously. Add the rest of the water and repeat shaking. After preparation, the solution must be stored in the refrigerator. Discard any unused portion after 14 days.

Contraindications

Description Contraindications Penicillin-VK Solution is an automatic translation from the original language.
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What is the most important information I should know about penicillin-VC solution?

Phenoxymethylpenicillin should not be given to patients allergic to penicillin and should be used with caution in patients with a history of cephalosporin allergy. Cases of cross sensitivity have been reported. Should not be given to neonatal children born to hypersensitive mothers. Not recommended for chronic, severe, or deep-seated infections such as subacute bacterial endocarditis, meningitis, or syphilis.

Special Warnings and Precautions

Description Special Warnings and Precautions Penicillin-VK Solution is an automatic translation from the original language.
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Use penicillin-VC solution as directed by your doctor. Check the label on the medication for exact dosing instructions.

  • Take penicillin-VC solution by mouth. A solution of penicillin-VC solution is best absorbed when taken on an empty stomach (1 hour before or 2 hours after a meal), but it can be taken with food.
  • Penicillin-VK Solution works best when taken at the same time each day.
  • Shake well before each use.
  • Use a measuring device marked for dosing medication. Ask your pharmacist for help if you are not sure how to measure your dose.
  • Throw away any unused medications after 14 days.
  • To completely clear the infection, take Penicillin-VK Solution for the full course of treatment. Keep taking even if you feel better after a few days.
  • Don’t miss a single dose. If you miss a dose of Penicillin-VC Solution, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and return to your regular dosing schedule. Do not take 2 doses at the same time.

Ask your doctor any questions about how to use Penicillin-VK Solution.

There are both specific and general uses of a drug or drug. A medicine can be used to prevent a disease, treat a disease for a period, or treat a disease. It can also be used to treat a specific symptom of a disease. The use of the drug depends on the form that the patient takes. It may be more useful in the form of an injection or sometimes in the form of a tablet. The drug may be used for a single alarm symptom or life-threatening condition. While some medications can be stopped after a few days, some medications must be continued for a long period of time to benefit from them.

Amoxicillin is used to treat a wide range of bacterial infections. This medicine is a penicillin antibiotic. It works by stopping the growth of bacteria.

This antibiotic only treats bacterial infections. This will not work for viral infections (such as colds, flu). Unnecessary use or misuse of any antibiotic can cause it to be less effective.

Amoxicillin is also used with other medicines to treat H. pylori stomach/intestinal ulcers and to prevent the ulcers from returning.

OTHER USES: This section contains uses of this drug that are not listed on the US approved occupational labeling for the drug but may be prescribed by your healthcare professional. Use this drug for the condition listed in this section only if it has been prescribed by your doctor.

This drug may also be used by people with certain heart problems (such as valvular heart disease) before medical/dental procedures (such as teeth/gum procedures) to prevent heart infection.

How to use penicillin-VC solution

Take this medicine by mouth with or without food as directed by your doctor, usually every 8 or 12 hours. Dosage is based on your medical condition and response to treatment.

Drink plenty of fluids while using this medicine unless your doctor tells you otherwise.

Antibiotics work best when the amount of medication in your body is kept constant. Therefore, take this drug at evenly spaced intervals. To help you remember, take it at the same time each day.

Continue taking this medicine until you have finished the full amount prescribed, even if the symptoms go away after a few days. Stopping the medication too early can allow the bacteria to continue to grow, which can lead to a return of the infection.

Tell your doctor if your condition persists or worsens.

Interaction with other drugs

Description Interaction with other drugs Penicillin-VK Solution is an automatic translation from the original language.
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What other drugs will affect penicillin-VC solution?

The effect of some medicines may change if you take other medicines or herbal products at the same time. This can increase your risk of serious side effects or cause your medications to not work properly. These drug interactions are possible but do not always occur. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medicines or by careful monitoring.

To help your doctor and pharmacist give you the best care, be sure to tell your doctor and pharmacist about all products you use (including prescription drugs, over-the-counter drugs, and herbal products) before starting treatment with this product. While using this product, do not start, stop, or change the dosage of any other medicines you are using without your doctor’s approval.

Some products that may interact with this drug include: live bacterial vaccines, methotrexate.

While most antibiotics are unlikely to affect hormonal birth control such as pills, patches, or rings, some antibiotics (such as rifampin, rifabutin) may reduce their effectiveness. This may lead to pregnancy. If you are using hormonal birth control, ask your doctor or pharmacist for more information.

Amoxicillin may cause false positive results with certain diabetic urine testing products (such as copper sulfate). This drug may also affect the results of certain lab tests. Make sure lab staff and your doctors know you are using this drug.

This document does not contain all possible drug interactions. Keep a list of all the products you use. Share this list with your doctor and pharmacist to reduce your risk of serious drug problems.

Side effects

Description Side effects Penicillin-VK Solution is an automatic translation from the original language.
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What are the possible side effects of the penicillin-VC solution?

Applies to penicillin-VC solution: capsule, solution powder, suspension powder, solution, suspension, syrup, tablet, suspension tablet, chewable tablet, extended release tablet

In addition to the desired effects, some undesirable effects the effects can be caused by a solution of penicillin-VC (the active ingredient contained in a solution of penicillin-VC). If any of these side effects occur, they may require medical attention.

Stop taking Penicillin-VK solution and get emergency help immediately if any of the following occur:

Less common:

  • Rapid or irregular breathing
  • fever
  • joint pain
  • lightheadedness or fainting (suddenly
  • puffiness or swelling around the face
  • red, scaly skin
  • shortness of breath
  • skin rash, urticaria, itching

Main side effects

You should consult your doctor immediately if any of these side effects occur while taking penicillin-VC solution:

Rare

  • Abdominal cramps e or stomach and pain (severe )
  • abdominal tenderness
  • convulsions (convulsions)
  • decreased amount of urine
  • diarrhea (watery and severe) that can also be bloody
  • mental depression
  • nausea and vomiting
  • injection site pain
  • sore throat and fever
  • unusual bleeding or bruising
  • yellow eyes or skin

90 081 Rare

  • Agitation or militancy
  • anxiety
  • confusion
  • fear of impending death
  • feeling, hearing or seeing things that are not real

Minor side effects

Some of the side effects that may occur with penicillin-VC solution may not require medical attention. As your body adjusts to the medication during treatment, these side effects may go away. Your health care provider can also tell you about ways to reduce or prevent some of these side effects. If any of the following side effects persist, are bothersome, or if you have any questions about them, check with your healthcare provider:

More common:

  • Diarrhea (mild)
  • Headache
  • pain in the mouth or tongue
  • vaginal itching and discharge
  • white patches in the mouth and/or tongue

Composition

Description The composition of Penicillin-VK Solution is an automatic translation from the original language.
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