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What is in diurex. Discover the Secrets of DIUREX: A Comprehensive Guide to Its Ingredients, Usage, and Potential Benefits

What are the active ingredients in DIUREX products? How should they be used? Can DIUREX help with water weight gain and bloating? Get the answers to these and other key questions about DIUREX.

The Crucial Components of DIUREX: Unveiling the Active Ingredients

DIUREX products, including DIUREX Max Water Caplets and DIUREX WATER PILLS, contain a range of active ingredients that work together to provide relief from temporary water weight gain, bloating, and other discomforts associated with the premenstrual and menstrual periods.

The key active ingredients in DIUREX Max Water Caplets are 50 mg of Pamabrom, a mild diuretic similar to caffeine but without the stimulating effects. In contrast, DIUREX WATER PILLS contain 162.5 mg of magnesium salicylate and 50 mg of caffeine as their active ingredients.

Dosage and Usage: Optimizing the Benefits of DIUREX

The recommended dosage for DIUREX Max Water Caplets is one caplet after breakfast with a full glass of water. This dose may be repeated after 6 hours, but should not exceed 4 caplets in a 24-hour period. It’s crucial to carefully read and follow the product’s Directions, Uses, and Warnings to ensure safe and effective use.

For DIUREX WATER PILLS, the recommended dosage is two pills every 4 to 6 hours, not to exceed eight pills per day. Again, it’s important to thoroughly review the product’s labeling and adhere to the instructions provided.

Exploring the Benefits: Does DIUREX Offer Relief for Water Weight and Bloating?

Yes, DIUREX products are designed to help relieve temporary water weight gain, bloating, and other discomforts associated with the premenstrual and menstrual periods. However, it’s important to note that DIUREX should not be used for purposes other than those indicated on the product package labeling without first consulting a healthcare professional.

It’s crucial to understand that DIUREX is not intended for continuous use. The product package labeling states that DIUREX should not be used for more than 10 consecutive days without consulting a doctor.

Compatibility and Precautions: Ensuring Safe Use of DIUREX

DIUREX products do not contain any sulfa drug ingredients, which is an important consideration for individuals with sulfa allergies.

However, it’s essential to consult with a healthcare provider before using DIUREX in conjunction with any prescription medications, as there may be potential interactions or contraindications. The safety and efficacy of DIUREX for purposes other than its intended use should also be discussed with a medical professional.

Addressing Specific Concerns: Can DIUREX Be Used by All?

DIUREX products are primarily designed to address water weight gain, bloating, and related discomforts associated with the premenstrual and menstrual periods. While some individuals may find DIUREX helpful for other water-related issues, such as swelling in the feet and ankles, it’s crucial to consult a healthcare provider before using the product for any purpose beyond its intended use.

It’s also important to note that DIUREX may not be suitable for individuals who no longer experience menstrual cycles, as the product is specifically formulated to address issues related to the premenstrual and menstrual periods. In such cases, it’s advisable to seek guidance from a healthcare professional.

Navigating the DIUREX Landscape: Answering Your Key Questions

Can DIUREX Max Water Caplets or DIUREX WATER PILLS help you lose weight? No, these products are not designed for weight loss. They are specifically formulated to provide relief from temporary water weight gain, bloating, and other discomforts associated with the premenstrual and menstrual periods.

Can DIUREX products “clean out your system”? No, DIUREX products are not intended to have a “cleansing” effect on the body. They are designed to address the specific issues of water weight gain and bloating related to the menstrual cycle.

Can men use DIUREX products? DIUREX products are primarily formulated to address issues related to the premenstrual and menstrual periods, so they may not be suitable for use by men. It’s recommended to consult a healthcare provider before using DIUREX for any purpose other than its intended use.

Empowering Your Health: Unlocking the Potential of DIUREX

By understanding the active ingredients, dosage, and intended uses of DIUREX products, you can make informed decisions about incorporating them into your health and wellness routine. Remember to always consult with a healthcare professional, especially if you have any underlying medical conditions or are taking other medications, to ensure the safe and effective use of DIUREX.

With this comprehensive guide, you’re equipped to navigate the world of DIUREX and explore the potential benefits it may offer for managing temporary water weight gain, bloating, and other discomforts associated with the premenstrual and menstrual periods.

DIUREX Max | Alva-Amco


What are DIUREX Max Water Caplets used for?

DIUREX Max Water Caplets help relieve temporary water weight gain, bloating and other discomforts associated with the premenstrual and menstrual periods.


What are the active ingredients in DIUREX Max Water Caplets?

Each DIUREX Max Water Caplet contains 50 mg of Pamabrom.


What is pamabrom?

Pamabrom is a mild diuretic ingredient that is similar to caffeine. It has the water-relieving activity of caffeine, without the stimulation of caffeine.


What is the dosage for DIUREX Max Water Caplets?

The dosage for DIUREX Max Water Caplets is one caplet after breakfast with a full glass of water. Dose may be repeated after 6 hours, not to exceed 4 caplets in 24 hours. Be sure to read all product package label Directions, Uses and Warnings and follow them carefully.


Do DIUREX Max Water Caplets contain any sulfa drugs?

No, DIUREX Max Water Caplets do not contain sulfa drug ingredients.


Do DIUREX Max Water Caplets help you lose weight?

DIUREX Max Water Caplets help relieve temporary water weight gain, bloating and other discomforts associated with the premenstrual and menstrual periods. We recommend that you ask your doctor or pharmacist before using DIUREX for a purpose other than that indicated on the product package labeling and follow his or her advice.


Do DIUREX Max Water Caplets “clean out your system”?

DIUREX Max Water Caplets help relieve temporary water weight gain, bloating and other discomforts associated with the premenstrual and menstrual periods. We recommend that you ask your doctor or pharmacist before using DIUREX for a purpose other than that indicated on the product package labeling and follow his or her advice.


Can I use DIUREX Max Water Caplets continuously?

DIUREX Max Water Caplets help relieve temporary water weight gain, bloating and other discomforts associated with the premenstrual and menstrual periods. The product package labeling states that you should not use DIUREX for more than 10 consecutive days without consulting your doctor.


Can I use DIUREX Max Water Caplets to remove the swelling in my feet and ankles?

DIUREX Max Water Caplets help relieve temporary water weight gain, bloating and other discomforts associated with the premenstrual and menstrual periods. We recommend that you ask your doctor or pharmacist before using DIUREX for a purpose other than that indicated on or in the product package labeling and follow his or her advice.


Can I use DIUREX Max Water Caplets with my prescription medication(s)?

You should ask your doctor or pharmacist if you can take DIUREX Max Water Caplets while you are using other medications.


I don’t have a period any more. Can I still use DIUREX Max Water Caplets?

DIUREX Max Water Caplets help relieve temporary water weight gain, bloating and other discomforts associated with the premenstrual and menstrual periods. We recommend that you ask your doctor or pharmacist before using DIUREX for a purpose other than that indicated on the product package labeling and follow his or her advice.


Can a man use DIUREX Max Water Caplets?

DIUREX Max Water Caplets help relieve temporary water weight gain, bloating and other discomforts associated with the premenstrual and menstrual periods. We recommend that you ask your doctor or pharmacist before using DIUREX for a purpose other than that indicated on the product package labeling and follow his or her advice.

DIUREX Water Pills + Pain Relief


What are DIUREX WATER PILLS used for?

DIUREX WATER PILLS help relieve temporary water weight gain, bloating and other discomforts associated with the premenstrual and menstrual periods.


What are the active ingredients in DIUREX WATER PILLS?

Each DIUREX WATER PILL contains 162.5 mg of magnesium salicylate and 50 mg of caffeine.


What is the dosage for DIUREX WATER PILLS?

The dosage for DIUREX WATER PILLS is two pills every 4 to 6 hours, not to exceed eight pills per day. Be sure to read all label Directions, Uses and Warnings and follow them carefully.


Do DIUREX WATER PILLS contain any sulfa drugs?

No, DIUREX WATER PILLS do not contain sulfa drug ingredients.


Are there any side effects associated with DIUREX WATER PILLS?

Information regarding the side effects which may be associated with DIUREX WATER PILLS may be found in the Warnings and Directions sections of Drug Facts for DIUREX WATER PILLS. Drug Facts may be found on the back panel of the DIUREX WATER PILLS package or on this website.


Do DIUREX WATER PILLS help you lose weight?

DIUREX WATER PILLS help relieve temporary water weight gain, bloating and other discomforts associated with the premenstrual and menstrual periods. We recommend that you ask your doctor or pharmacist before using DIUREX for a purpose other than that indicated on the product package labeling and follow his or her advice.


Do DIUREX WATER PILLS “clean out your system”?

DIUREX WATER PILLS help relieve temporary water weight gain, bloating and other discomforts associated with the premenstrual and menstrual periods. We recommend that you ask your doctor or pharmacist before using DIUREX for a purpose other than that indicated on the product package labeling and follow his or her advice.


Can I use DIUREX WATER PILLS continuously?

DIUREX WATER PILLS help relieve temporary water weight gain, bloating and other discomforts associated with the premenstrual and menstrual periods. The product package labeling states that you should not use DIUREX for more than 10 consecutive days without consulting your doctor.


Can I use DIUREX WATER PILLS to remove the swelling in my feet and ankles?

DIUREX WATER PILLS help relieve temporary water weight gain, bloating and other discomforts associated with the premenstrual and menstrual periods. We recommend that you ask your doctor or pharmacist before using DIUREX for a purpose other than that indicated on or in the product package labeling and follow his or her advice.


Can I use DIUREX WATER PILLS with my prescription medications(s)?

You should ask your doctor or pharmacist if you can take DIUREX WATER PILLS while you are using other medications.


I don’t have a period any more. Can I still use DIUREX WATER PILLS?

DIUREX WATER PILLS help relieve temporary water weight gain, bloating and other discomforts associated with the premenstrual and menstrual periods. We recommend that you ask your doctor or pharmacist before using DIUREX for a purpose other than that indicated on the product package labeling and follow his or her advice.


Can a man use DIUREX WATER PILLS?

DIUREX WATER PILLS help relieve temporary water weight gain, bloating and other discomforts associated with the premenstrual and menstrual periods. We recommend that you ask your doctor or pharmacist before using DIUREX for a purpose other than that indicated on the product package labeling and follow his or her advice.


Will DIUREX WATER PILLS show up on a drug test?

We have not had reports of the active ingredients in DIUREX WATER PILLS showing up on a drug test. However, as indicated in or on the product package labeling, DIUREX WATER PILLS may turn your urine blue or blue-green, which may be an issue in a urine test.


Do DIUREX WATER PILLS make your urine blue?

As stated on or in the product package labeling, blue or blue-green tinted urine when using DIUREX WATER PILLS is a normal and temporary effect.

Diurex (Xipamide) – instructions for use, dosage, composition, analogues, side effects / Pillintrip

Page reviewed by pharmacist Olga Valerievna Fedorchenko Last update 2022-04-02

Top 20 medicines with the same ingredients: d – 1 A PharmaXipamid AbZXipamid StadaXipamid-ratiopharmAquaphorNeotriXipamid AAA-Pharma

Name of the drug

Description The name of the drug Diurex (Xipamide) is an automatic translation from the original language.
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Diurex (Xipamide)

Composition

Description Composition Diurex (Xipamide) is an automatic translation from the original language.
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Xipamide

Therapeutic indications

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For the treatment of hypertension, alone or as an adjunct to treatment with antihypertensive drugs.

For use as a diuretic.

Dosage and Administration

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1. Treatment of hypertension

Dosage:

Adults : 1 tablet (20 mg) per day as a single early morning dose. When using Diurex (Xipamide) in combination with other antihypertensive therapy, the same dose of 20 mg as a single early morning dose should be maintained.

Children : Dose not recommended.

Elderly : See Respect.

2. Use as a diuretic

Dosage :

Adults : At the initial stage of treatment, the usual dose is 2 tablets (40 mg) per day in a single early morning dose. Depending on the response of the patient, the dose may be reduced to 1 tablet per day when sufficient control of edema has been achieved. In resistant cases, higher doses may be used, up to 4 tablets per day (80 mg).

Children : Dose not recommended.

Elderly people : See “Respects”.

Contraindications

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Diurex (xipamide) is contraindicated in severe electrolyte deficiency, precoma associated with liver cirrhosis, severe renal failure, hypersensitivity to xipamide, untreated Addison’s disease, hypercalcemia, pre-existing hypovolemia, symptomatic hyperuricemia, pregnancy and lactation .

Special Warnings and Precautions

Description Special Warnings and Precautions Diurex (Xipamide) is an automatic translation from the original language.
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In patients with liver disease, therapy with thiazide diuretics and related substances may cause hepatic encephalopathy. In this case, treatment with Diurex (Xipamide) should be stopped immediately.

Some cases of photosensitivity have been reported with the use of thiazide diuretics.

If a photosensitivity reaction occurs during treatment, xipamide should be discontinued. If re-administration of treatment cannot be avoided, the skin area exposed to sunlight or artificial UVA should be protected.

Pseudo-Bartter may occur in case of chronic abuse of diuretics.

Patients with rare hereditary fructose intolerance, glucose-galactose malabsorption, or sucrose-isomaltose intolerance should not take Diurex (Xipamide).

As with all antihypertensive agents, caution should be exercised in patients with severe coronary or cerebral arteriosclerosis.

An increased risk of urinary retention may occur in patients with prostatic hypertrophy.

Precautions for use of the drug:

Water and electrolyte balance:

Plasma sodium:

Plasma sodium should be monitored prior to initiation of therapy and at regular intervals during treatment. In principle, hyponatremia can occur with any diuretic treatment, with very serious complications. Since a decrease in plasma sodium levels may initially pass asymptomatically, regular monitoring is necessary; elderly patients and patients with cirrhosis of the liver should be carefully monitored (cf. adverse effects and overdose).

Potassium level:

As with other diuretics, hypokalemia may occur during long-term therapy with xipamide. Serum electrolytes (particularly potassium, sodium, calcium), bicarbonate, creatinine, urea, uric acid, and blood sugar should be monitored regularly. Potassium replacement may be required, especially in elderly patients with insufficient potassium intake.

Decreased potassium levels to the point of hypokalemia is the main risk of treatment with thiazide diuretics and closely related drugs. The occurrence of hypokalemia (plasma potassium level <3.4 mmol/l) should be avoided, especially in case of greater fluid loss (e.g. due to vomiting, diarrhea or intense sweating) and in risk groups, i.e. in elderly and / or malnourished patients and / or patients receiving treatment with several drugs, as well as in patients with cirrhosis of the liver and the formation of edema or ascites, moreover, in patients with coronary heart disease and patients with heart failure. In this group of patients, hypokalemia will also increase the cardiotoxicity of cardiac glycosides and the risk of cardiac dysrhythmia.

Hypovolemia or dehydration, as well as severe electrolyte or acid-base disturbances, must be corrected. This may require a temporary discontinuation of xipamide treatment.

Individuals with congenital or iatrogenic acquired long QT intervals are also at high risk. The presence of hypokalemia and bradycardia will contribute to the occurrence of severe arrhythmias, in particular the possible lethal pointe de torsade (polymorphic ventricular tachycardia).

All of the above cases require frequent monitoring of potassium levels, starting the first monitoring within the first week after starting therapy. Hypokalemia must be corrected.

Plasma calcium level:

Treatment with thiazide diuretics and related drugs may result in a decrease in urinary calcium excretion and a slight transient increase in plasma calcium levels. It is possible that the apparent hypercalcemia was due to a previous unexplored hyperparatriosis.

Xipamide therapy should be discontinued pending a possible study of parathyroid function.

Blood sugar level:

Especially in diabetic patients with concomitant hypokalemia, blood sugar levels should be carefully monitored.

Uric acid level:

Patients with hyperuricemia may have an increased tendency to acute gouty arthritis.

Renal function and diuretics:

Thiazide and related substances are only effective in normal or at least mild renal impairment (serum creatinine <25 mg/l or <220 Î1⁄4mol/l in adults ). In elderly patients, this serum creatinine value should be adjusted according to the age, weight and sex of the respective patient.

Hypovolemia caused by loss of water and sodium associated with diuretics at the beginning of therapy leads to a decrease in glomerular filtration rate. This can cause an increase in blood urea nitrogen (BUN) and serum creatinine. This temporary functional renal insufficiency remains without sequelae in healthy renal individuals, but may exacerbate pre-existing renal insufficiency.

In the event of treatment-resistant electrolyte decompensation, therapy should be discontinued.

Effects on ability to drive and use machines

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Xipamide may cause dizziness and electrolyte disturbances which may affect the patient’s concentration or alertness and may affect the patient’s ability to drive or operate machinery safely. This is especially true for initiation of treatment or dose changes. When affected, patients should not drive or operate a car.

Side effects

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The following side effects may occur when using thiazide diuretics and related drugs, including xipamide. With regard to clinical and chemical parameters, most adverse effects are dose dependent.

Rarely, anaphylactoid reactions may occur.

Latent diabetes mellitus may appear. In patients with diabetes, glucose levels may be increased.

At high doses, the risk of thrombosis and embolism is increased, especially in previous existing venous disorders.

Adverse events are listed below by system organ class and frequency. Frequencies are defined as: very common (> 1/l0), common (> 1/100 and <1/10), uncommon (> 1/1000 and <1/100), rare (> 1/10000 and <1/1000 ) and very rare (<1/1000), including available data cannot be known from.

Disorders of the blood and lymphatic system

Very rare: Thrombocytopenia, leukopenia, agranulocytosis, aplastic anemia (discontinuation of therapy)

Metabolic and nutritional disorders

Rare: Hyperlipidemia

Psychiatric disorders

General: Lethargy, restlessness, agitation

Nervous system disorders

Common: Headache, dizziness, dry mouth, fatigue, sweating

Visual disturbances

Rare: Minor visual disturbances, exacerbation of existing myopia (discontinuation of therapy)

Cardiac disorders

General: Palpitations

Vascular disorders

General: Orthostatic hypotension

Gastrointestinal disorders

Common: Upper abdominal discomfort, abdominal cramps, diarrhea, constipation

Rare: Hemorrhagic pancreatitis (discontinuation of therapy)

Hepatobiliary disorders

Rare: Acute cholecystitis in case of or pre-existing cholelithiasis (discontinuation of therapy)

Very rare: Jaundice (icterus)

Skin and subcutaneous tissue disorders

Uncommon: Photosensitive reactions

Rare: Allergic skin reactions (pruritus, erythema, urticaria) (discontinuation of therapy)

Musculoskeletal system and connective tissue

General : Muscle spasms/convulsions

Renal and urinary disorders

Very common: Hypokalemia which may become apparent with symptoms such as nausea, vomiting, ECG changes, glycoside hypersensitivity, arrhythmia or hypotension skeletal muscles.

General: Electrolyte and fluid disorders such as dehydration, hyponatremia, hypomagnesemia, hypochloremic alkalosis. Reversible increase in nitrogenous substances excreted in the urine (urea, creatinine), especially at the beginning of treatment. Elevated serum uric acid levels and triggering acute gouty arthritis in predisposed patients.

Very rare: Acute interstitial nephritis.

Therapy should be discontinued if:

– treatment-resistant electrolyte imbalance

– orthostatic regulatory disorders

– Hypersensitivity reactions

– Distinct gastrointestinal complaints

– Central nervous disorders

– Pancreatitis 9000 3

– changes in the blood (anemia, leukopenia, thrombocytopenia)

– acute cholecystitis

– occurrence of vasculitis

– exacerbation of existing myopia

Reporting suspected adverse reactions

Reporting suspected adverse reactions after drug approval is important. This allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are encouraged to report any suspected adverse reactions through the Yellow Card Scheme at:

www.mhra.gov.uk/yellowcard

Overdose

Description Overdose Diurex (Xipamide) is an automatic translation from the original language.
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There is no specific antidote for xipamide. Acute intoxications are manifested especially in violations of electrolytes and fluid balance (hyponatremia, hypokalemia). Clinical symptoms such as nausea, vomiting, drop in blood pressure, convulsions, dizziness, drowsiness, confusion, polyuria or oliguria and anuria (due to hypovolemia) may occur.

Emergency procedures: detoxification by administration of activated charcoal; subsequently restoration of the normal balance of water and electrolytes in a specialized center.

Gastric lavage or induced emesis may prevent further absorption. General measures should be aimed at maintaining blood pressure, restoring blood volume, and correcting electrolyte imbalances with appropriate intravenous infusion as needed.

Pharmacodynamics

Description Pharmacodynamics Diurex (Xipamide) is an automatic translation from the original language.
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Xipamide is an antihypertensive diuretic that can be characterized pharmacologically as neither a thiazide nor a specific loop diuretic. Although structurally similar to chlorthalidone, it has a markedly different pharmacological profile, with its primary diuretic effect acting on the distal nephron.

As a diuretic, xipamide has been shown to be as effective as frachsemide in terms of daily urine output, but has a more gradual and prolonged effect.

Pharmacokinetics

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After a single oral dose of 20 mg xipamide, peak plasma concentrations of up to 3 µg/ml occur within 1 hour. Absolute bioavailability after oral administration is about 73%.

Xipamide is closely bound to plasma protein and has a volume of distribution of about 10 liters. After oral or i.v. administration, apparent removal t½ is on the order of 5-8 hours. About 90% oral or i.v. the dose is excreted in the urine, with 50% of the dose excreted in the urine unchanged and another 30% as a 0-0 glucuronide.

Preclinical Safety Data Sheet

Description Preclinical Safety Data Sheet Diurex (Xipamide) is an automatic translation from the original language.
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Doesn’t matter.

Interaction

Description Interaction Diurex (Xipamide) is an automatic translation from the original language.
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